Guide to the Human Genome
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Name: THPO Sequence: fasta or formatted (353aa) NCBI GI: 4507493
Description:

thrombopoietin precursor

Referenced in:

Platelets and Megakaryocytes
Hematopoiesis and Erythrocytes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         18           2
 C cysteine            1.1          4           1
 D aspartate           2.5          9           1
 E glutamate           3.1         11           2
 F phenylalanine       2.3          8           1
 G glycine             7.9         28           2
 H histidine           2.5          9           1
 I isoleucine          1.7          6           1
 K lysine              2.0          7           1
 L leucine            19.3         68           3
 M methionine          1.4          5           1
 N asparagine          2.8         10           1
 P proline            11.3         40           2
 Q glutamine           5.4         19           2
 R arginine            5.7         20           2
 S serine              9.1         32           2
 T threonine          10.2         36           2
 V valine              4.8         17           2
 W tryptophan          0.6          2           1
 Y tyrosine            1.1          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thrombopoietin precursor 
RICH2                 0.032   Rho GTPase-activating protein RICH2 
RBM12                 0.029   RNA binding motif protein 12 
RBM12                 0.029   RNA binding motif protein 12 
ACR                   0.028   acrosin precursor 
LOC645529             0.026   PREDICTED: similar to Putative acrosin-like proteas...
UBAP2L                0.025   ubiquitin associated protein 2-like isoform a [Homo...
UBAP2L                0.025   ubiquitin associated protein 2-like isoform b [Homo...
HOXA3                 0.023   homeobox A3 isoform a 
HOXA3                 0.023   homeobox A3 isoform a 
HTT                   0.022   huntingtin 
FIP1L1                0.022   FIP1 like 1 isoform 1 
WASF2                 0.022   WAS protein family, member 2 
SETD1B                0.022   SET domain containing 1B 
FLJ22184              0.021   PREDICTED: hypothetical protein FLJ22184 
FLJ22184              0.021   PREDICTED: hypothetical protein LOC80164 
FIP1L1                0.021   FIP1 like 1 isoform 2 
PIAS3                 0.021   protein inhibitor of activated STAT, 3 
CPSF6                 0.021   cleavage and polyadenylation specific factor 6, 68 ...
NCCRP1                0.021   non-specific cytotoxic cell receptor protein 1 homol...
MAPK1IP1L             0.021   MAPK-interacting and spindle-stabilizing protein [Ho...
MUC2                  0.021   mucin 2 precursor 
LOC100128719          0.021   PREDICTED: hypothetical protein, partial 
LOC100128719          0.021   PREDICTED: hypothetical protein, partial 
WASL                  0.019   Wiskott-Aldrich syndrome gene-like protein 
PRRT2                 0.019   proline-rich transmembrane protein 2 
PHLDB1                0.019   pleckstrin homology-like domain, family B, member 1...
PHLDB1                0.019   pleckstrin homology-like domain, family B, member 1...
PHLDB1                0.019   pleckstrin homology-like domain, family B, member 1 ...
LOC284297             0.019   hypothetical protein LOC284297 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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