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Search of human proteins with 4507347
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507347 TBP-associated factor 2 [Homo sapiens]
(1199 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507347 TBP-associated factor 2 [Homo sapiens] 2451 0.0
gi|21361684 G patch domain containing 1 [Homo sapiens] 49 4e-05
gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] 48 6e-05
gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 45 4e-04
gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 45 4e-04
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 44 7e-04
gi|11225260 DNA topoisomerase I [Homo sapiens] 44 0.001
gi|134288896 hypothetical protein LOC143684 [Homo sapiens] 43 0.002
gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 43 0.002
gi|94818891 type 1 tumor necrosis factor receptor shedding amino... 43 0.002
gi|94818901 type 1 tumor necrosis factor receptor shedding amino... 43 0.002
gi|17978466 cyclin T1 [Homo sapiens] 43 0.002
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 43 0.002
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 42 0.004
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 42 0.004
gi|122937233 discs, large (Drosophila) homolog-associated protei... 42 0.004
gi|132814467 glutamyl aminopeptidase [Homo sapiens] 42 0.005
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 42 0.005
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] 41 0.006
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] 41 0.006
gi|32698730 nuclear fragile X mental retardation protein interac... 40 0.010
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 40 0.013
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 40 0.013
gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens] 39 0.023
gi|153252201 solute carrier family 39 (zinc transporter), member... 39 0.030
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 39 0.039
gi|149408126 nemo like kinase [Homo sapiens] 38 0.051
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 38 0.051
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 38 0.051
gi|13236559 hypothetical protein LOC79169 [Homo sapiens] 38 0.051
>gi|4507347 TBP-associated factor 2 [Homo sapiens]
Length = 1199
Score = 2451 bits (6352), Expect = 0.0
Identities = 1199/1199 (100%), Positives = 1199/1199 (100%)
Query: 1 MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANL 60
MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANL
Sbjct: 1 MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANL 60
Query: 61 NRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPD 120
NRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPD
Sbjct: 61 NRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPD 120
Query: 121 AGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLHFVVPSVEGSMAERGAHVFSC 180
AGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLHFVVPSVEGSMAERGAHVFSC
Sbjct: 121 AGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLHFVVPSVEGSMAERGAHVFSC 180
Query: 181 GYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTI 240
GYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTI
Sbjct: 181 GYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTI 240
Query: 241 PTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYP 300
PTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYP
Sbjct: 241 PTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYP 300
Query: 301 YSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFIS 360
YSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFIS
Sbjct: 301 YSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFIS 360
Query: 361 RMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLHPIFGG 420
RMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLHPIFGG
Sbjct: 361 RMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLHPIFGG 420
Query: 421 GKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLA 480
GKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLA
Sbjct: 421 GKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLA 480
Query: 481 STASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRK 540
STASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRK
Sbjct: 481 STASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRK 540
Query: 541 RNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNK 600
RNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNK
Sbjct: 541 RNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNK 600
Query: 601 KKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVV 660
KKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVV
Sbjct: 601 KKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVV 660
Query: 661 AQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMK 720
AQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMK
Sbjct: 661 AQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMK 720
Query: 721 SLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIK 780
SLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIK
Sbjct: 721 SLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIK 780
Query: 781 YNDNRKNKFSDNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNME 840
YNDNRKNKFSDNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNME
Sbjct: 781 YNDNRKNKFSDNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNME 840
Query: 841 KLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIRIAALEAVVDYTKV 900
KLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIRIAALEAVVDYTKV
Sbjct: 841 KLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIRIAALEAVVDYTKV 900
Query: 901 DRSYEELQWLLNMIQNDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSG 960
DRSYEELQWLLNMIQNDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSG
Sbjct: 901 DRSYEELQWLLNMIQNDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSG 960
Query: 961 TSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVAGNQEA 1020
TSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVAGNQEA
Sbjct: 961 TSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVAGNQEA 1020
Query: 1021 ANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPAS 1080
ANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPAS
Sbjct: 1021 ANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPAS 1080
Query: 1081 SRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTA 1140
SRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTA
Sbjct: 1081 SRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTA 1140
Query: 1141 SKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSLSD 1199
SKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSLSD
Sbjct: 1141 SKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSLSD 1199
>gi|21361684 G patch domain containing 1 [Homo sapiens]
Length = 931
Score = 48.5 bits (114), Expect = 4e-05
Identities = 56/180 (31%), Positives = 72/180 (40%), Gaps = 18/180 (10%)
Query: 1021 ANNPSSHPQLVGFQNPFSSSQDEE----EIDMDTVHDSQAFISHHLNMLERPSTPGLSKY 1076
A S P + F+ F+SS DE+ E + D QA S N T
Sbjct: 742 AEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG-SGEANFQSSQDT---DLG 797
Query: 1077 RPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTK 1136
+S AL+P S P K Q R+ G P+ P A L V K
Sbjct: 798 ETSSVAHALVPAPQEPPPSFPIQKMQID---EREEFGPRLPPV---FCPNARQTLEVPQK 851
Query: 1137 ESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPS 1196
E K+ D H +KK+KK KH+ KHKH K+K+K+P SS S S S S
Sbjct: 852 EKH-KKNKDKHKAKKEHRRKKEKKKKHR---KHKHKGKQKNKKPEKSSSSESSDSSDSQS 907
>gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]
Length = 919
Score = 47.8 bits (112), Expect = 6e-05
Identities = 83/401 (20%), Positives = 148/401 (36%), Gaps = 58/401 (14%)
Query: 190 FPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETV-YTHDMRKKTFHYMLTIPTAASNIS 248
FPC D + T+ + V VA+SN ++++ Y D + T + ++
Sbjct: 188 FPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVA 247
Query: 249 LAIGPFEILVDPYMHEVTHFCLPQLLPLLK-----HTTSYLHEVFEFYEEILTCRYPYSC 303
+G ++ + V C+ P+ K + FY++ YP
Sbjct: 248 FVVGEYDFVETRSKDGV---CVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPK 304
Query: 304 FKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIID---ETPLTRRCLA----QSLAQQFFG 356
+ A + AA A + +A++ID +R+ +A LA Q+FG
Sbjct: 305 IDLI----AIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFG 360
Query: 357 CFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIK-EELDKIVAYELKTGGVLLH 415
++ W+ W+ +G + +I L + F EY W + D A EL
Sbjct: 361 NLVTMEWWTHLWLNEGFASWIEYLCVDHCF--PEYDIWTQFVSADYTRAQELDA------ 412
Query: 416 PIFGGGKEKDNPASH-LHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFN 474
DN SH + S+ HP + + + K V+R++ + I + + N
Sbjct: 413 --------LDN--SHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMN 462
Query: 475 KLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGS 534
L+ KFQ Q +T +S+ N SGK I ++ W Q G Y
Sbjct: 463 MYLT--------KFQ-----QKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVE 509
Query: 535 FAFNRKRNVLELEIKQ-----DYTSPGTQKYVGPLKVTVQE 570
+L L K+ Y +++ P+ ++ E
Sbjct: 510 AEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSE 550
>gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 45.1 bits (105), Expect = 4e-04
Identities = 49/216 (22%), Positives = 91/216 (42%), Gaps = 28/216 (12%)
Query: 187 RFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------GDLVETVYTHDMRKKTF-- 234
R FPC D + ++ ++ +A+SN G L+E + ++ T+
Sbjct: 205 RMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLV 264
Query: 235 HYMLTIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEI 294
Y++ + S + + I P TH+ L L LL +FYE+
Sbjct: 265 AYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLL-----------DFYEKY 313
Query: 295 LTCRYPYSCFKTVFI-DEAYVEVAAYASMSIFSTNLLH---SAMIIDETPLTRRCLAQSL 350
YP S + I D A + + ++ T+LL ++ D+ +TR +A L
Sbjct: 314 FDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTR-VIAHEL 372
Query: 351 AQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTF 386
A Q+FG ++ W+D W+ +G + Y+ + + T+
Sbjct: 373 AHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATY 408
>gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 45.1 bits (105), Expect = 4e-04
Identities = 49/216 (22%), Positives = 91/216 (42%), Gaps = 28/216 (12%)
Query: 187 RFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------GDLVETVYTHDMRKKTF-- 234
R FPC D + ++ ++ +A+SN G L+E + ++ T+
Sbjct: 205 RMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLV 264
Query: 235 HYMLTIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEI 294
Y++ + S + + I P TH+ L L LL +FYE+
Sbjct: 265 AYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLL-----------DFYEKY 313
Query: 295 LTCRYPYSCFKTVFI-DEAYVEVAAYASMSIFSTNLLH---SAMIIDETPLTRRCLAQSL 350
YP S + I D A + + ++ T+LL ++ D+ +TR +A L
Sbjct: 314 FDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTR-VIAHEL 372
Query: 351 AQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTF 386
A Q+FG ++ W+D W+ +G + Y+ + + T+
Sbjct: 373 AHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATY 408
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 44.3 bits (103), Expect = 7e-04
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 16/60 (26%)
Query: 1135 TKESTASKHSDHH---HHHHHEHKKKK--------KKHKHKHKHKHKHDSKE----KDKE 1179
+++ + +KHS H H H +HKK K KKHKHKHKHK KH KE DKE
Sbjct: 32 SEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHK-KHKRKEIIDASDKE 90
Score = 43.9 bits (102), Expect = 0.001
Identities = 22/44 (50%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Query: 1137 ESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKE-KDKE 1179
E D + H HKKKK KH+ KHK KHKH S+E KDK+
Sbjct: 26 EENGEVSEDQSQNKHSRHKKKKHKHRSKHK-KHKHSSEEDKDKK 68
Score = 38.1 bits (87), Expect = 0.051
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 14/66 (21%)
Query: 1127 ASAPLSVFTKESTASKHSDHHHHHHHEHKKKKK-----KHKH--------KHKHKHKHDS 1173
A++ S+ + S+ + H H+ KK K KHKH KHKHKHKH
Sbjct: 18 ANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKH-K 76
Query: 1174 KEKDKE 1179
K K KE
Sbjct: 77 KHKRKE 82
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/44 (45%), Positives = 24/44 (54%)
Query: 1136 KESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKE 1179
KE K + H + EHK +KKHK K K KHK S EK K+
Sbjct: 36 KEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKD 79
Score = 42.7 bits (99), Expect = 0.002
Identities = 19/41 (46%), Positives = 24/41 (58%), Gaps = 3/41 (7%)
Query: 1142 KHSDHH---HHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKE 1179
KH D H H H EHKK+K + K KH + DS++K KE
Sbjct: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKE 63
Score = 41.2 bits (95), Expect = 0.006
Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query: 1136 KESTASKHSDHHHHHHHEHKKKKKKHKHK------HKHKHKHDSKEKDKE 1179
K+ SKHS+ H + K+K+K KHK HK KHK KEK KE
Sbjct: 42 KDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKE 91
Score = 33.1 bits (74), Expect = 1.6
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 1144 SDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDK 1178
+D + H+HK K K +H+HK K +EK K
Sbjct: 14 ADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSK 48
Score = 31.6 bits (70), Expect = 4.7
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 1136 KESTASKHSDHHHHHHHE-HKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSP 1186
KE +KH D H + HK + K+ + + K + D+K K ++ FSSP
Sbjct: 62 KEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSP 113
>gi|134288896 hypothetical protein LOC143684 [Homo sapiens]
Length = 339
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 13/90 (14%)
Query: 1114 KEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHEHKKKKKK------------H 1161
KEQ S H +S+ S+ K+ KH HHHHHHH H K
Sbjct: 143 KEQRKSLGSSHSNSSSS-SLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNLSPEEEQGLW 201
Query: 1162 KHKHKHKHKHDSKEKDKEPFTFSSPASGRS 1191
K HK ++ K+P S P++G S
Sbjct: 202 KQSHKSSATIQNETPKKKPKLESKPSNGDS 231
>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
Length = 908
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 8/64 (12%)
Query: 1143 HSDHHHHHHHEHKKKKKKHKHKHKHKHK--------HDSKEKDKEPFTFSSPASGRSIRS 1194
H HHHHHHH H+ + + H H H+ +S D E ++S A+ S
Sbjct: 340 HHHHHHHHHHHHRAQPPQQSHHPPHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFG 399
Query: 1195 PSLS 1198
SLS
Sbjct: 400 SSLS 403
>gi|94818891 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform b [Homo sapiens]
Length = 941
Score = 42.7 bits (99), Expect = 0.002
Identities = 40/202 (19%), Positives = 87/202 (43%), Gaps = 14/202 (6%)
Query: 185 STRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAA 244
+ R FPC D + ++ ++ + +A+SN LV++V + + H+ +T+ +
Sbjct: 186 AARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED-HFDVTVKMST 244
Query: 245 SNISLAIGPFEIL--VDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYS 302
++ I FE + + +V+ + +P + + + EFYE+ + YP
Sbjct: 245 YLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLP 304
Query: 303 CFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRC-------LAQSLAQQFF 355
I + + A + + T SA++ D + +A LA Q+F
Sbjct: 305 KQDLAAIPD--FQSGAMENWGL--TTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
Query: 356 GCFISRMSWSDEWVLKGISGYI 377
G ++ W+D W+ +G + ++
Sbjct: 361 GNLVTMEWWNDLWLNEGFAKFM 382
>gi|94818901 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform a [Homo sapiens]
Length = 948
Score = 42.7 bits (99), Expect = 0.002
Identities = 40/202 (19%), Positives = 87/202 (43%), Gaps = 14/202 (6%)
Query: 185 STRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAA 244
+ R FPC D + ++ ++ + +A+SN LV++V + + H+ +T+ +
Sbjct: 186 AARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED-HFDVTVKMST 244
Query: 245 SNISLAIGPFEIL--VDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYS 302
++ I FE + + +V+ + +P + + + EFYE+ + YP
Sbjct: 245 YLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLP 304
Query: 303 CFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRC-------LAQSLAQQFF 355
I + + A + + T SA++ D + +A LA Q+F
Sbjct: 305 KQDLAAIPD--FQSGAMENWGL--TTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
Query: 356 GCFISRMSWSDEWVLKGISGYI 377
G ++ W+D W+ +G + ++
Sbjct: 361 GNLVTMEWWNDLWLNEGFAKFM 382
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/185 (24%), Positives = 68/185 (36%), Gaps = 58/185 (31%)
Query: 1043 EEEIDMDTVHDSQAFISHH-----------LNMLERPSTPGLSKYRPASSRSAL---IPQ 1088
E + + +Q +SHH + E P P L K + ++AL IP
Sbjct: 411 EANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEK----ADKTALKMRIPV 466
Query: 1089 HSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHH- 1147
AG D ++KP E+ + + +H AA SV + + +H + H
Sbjct: 467 --AGGDKAASSKP-------------EEIKMRIKVHAAADKHNSVEDSVTKSREHKEKHK 511
Query: 1148 -----HHHHHEHKKKKKKHKHKHKHKH-------------KHDSKEKDKEPFTFSSPASG 1189
HHHHH H H HKH H KH S+ + T+S +S
Sbjct: 512 THPSNHHHHHNH------HSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSF 565
Query: 1190 RSIRS 1194
S S
Sbjct: 566 SSSSS 570
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 42.7 bits (99), Expect = 0.002
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 1130 PLSVFTKESTASKHSDHHHHHHHEHK---KKKKKHKHKHKHKHKHDSKEKDKEPF 1181
P V TK + + HHHHH H H+ K +K + KHK KH + EKD+ F
Sbjct: 1267 PQIVCTKPRRSHRMRRHHHHHQHHHQHHHHKSRKERRKHK-KHPTEDWEKDEGNF 1320
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 42.0 bits (97), Expect = 0.004
Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 13/98 (13%)
Query: 1096 TPTTKPQWSLELARKGTGKEQAPLEMSM--HPAASAPLSVFTKESTASKHSDHHHHHHHE 1153
+P + Q+ L GT +AP ++++ HP V +++ H + HHHH
Sbjct: 546 SPQVRQQFPAPLGWSGT---EAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHH 602
Query: 1154 HKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRS 1191
H H H H H + P ++SP + S
Sbjct: 603 H--------HHHHHHHGQQALGNRTRPRVYNSPTNSSS 632
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 42.0 bits (97), Expect = 0.004
Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 13/98 (13%)
Query: 1096 TPTTKPQWSLELARKGTGKEQAPLEMSM--HPAASAPLSVFTKESTASKHSDHHHHHHHE 1153
+P + Q+ L GT +AP ++++ HP V +++ H + HHHH
Sbjct: 555 SPQVRQQFPAPLGWSGT---EAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHH 611
Query: 1154 HKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRS 1191
H H H H H + P ++SP + S
Sbjct: 612 H--------HHHHHHHGQQALGNRTRPRVYNSPTNSSS 641
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 42.0 bits (97), Expect = 0.004
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 8/37 (21%)
Query: 1143 HSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKE 1179
H+ HHHHHHH H H H+ +H SK KD++
Sbjct: 220 HTSHHHHHHHHH--------HHHQSRHGKRSKSKDRK 248
Score = 37.7 bits (86), Expect = 0.066
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 1139 TASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSK 1174
T+ H HHHHHHH+ + K+ K +H +K
Sbjct: 221 TSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAK 256
Score = 37.4 bits (85), Expect = 0.086
Identities = 15/42 (35%), Positives = 20/42 (47%)
Query: 1144 SDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSS 1185
S HHHHHHH H + + K K D + + K +SS
Sbjct: 222 SHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSS 263
Score = 32.7 bits (73), Expect = 2.1
Identities = 12/31 (38%), Positives = 15/31 (48%)
Query: 1143 HSDHHHHHHHEHKKKKKKHKHKHKHKHKHDS 1173
H HHHHH H K+ K K +H+ S
Sbjct: 227 HHHHHHHHQSRHGKRSKSKDRKGDGRHQAKS 257
>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
Length = 957
Score = 41.6 bits (96), Expect = 0.005
Identities = 37/192 (19%), Positives = 78/192 (40%), Gaps = 6/192 (3%)
Query: 190 FPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAASNISL 249
FPC D ++ T+ + T A+SN + + D +T + ++P + +
Sbjct: 231 FPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTT-FEKSVPMSTYLVCF 289
Query: 250 AIGPFEIL--VDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSCFKTV 307
A+ F+ + + +T + P+ ++ + VF+++EE Y +
Sbjct: 290 AVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKI 349
Query: 308 FI-DEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTR--RCLAQSLAQQFFGCFISRMSW 364
I D + + ++ TNLL+ + R +A L Q+FG ++ W
Sbjct: 350 AIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWW 409
Query: 365 SDEWVLKGISGY 376
D W+ +G + +
Sbjct: 410 EDLWLNEGFASF 421
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 41.6 bits (96), Expect = 0.005
Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 7/55 (12%)
Query: 1117 APLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKH 1171
AP+ HP +P++ S + HHHHH H H + H H H H H
Sbjct: 253 APMHSHHHPHQLSPMA-------PSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH 300
>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
Length = 1025
Score = 41.2 bits (95), Expect = 0.006
Identities = 38/206 (18%), Positives = 84/206 (40%), Gaps = 5/206 (2%)
Query: 185 STRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAA 244
+ R FPC D + T+ ++ D A+SN +V D + + ++ +
Sbjct: 298 AARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQD-EFSESVKMST 356
Query: 245 SNISLAIGPFEILV-DPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSC 303
++ +G + L D V+ + +P+ + + + ++ EF++ +YP
Sbjct: 357 YLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKK 416
Query: 304 FKTVFIDEAYVEVAAYASMSIFSTNLL---HSAMIIDETPLTRRCLAQSLAQQFFGCFIS 360
V I + + F L + + + L + +A LA Q+FG ++
Sbjct: 417 LDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVT 476
Query: 361 RMSWSDEWVLKGISGYIYGLWMKKTF 386
W+D W+ +G + ++ ++K F
Sbjct: 477 MKWWNDLWLNEGFATFMEYFSLEKIF 502
>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
Length = 1011
Score = 41.2 bits (95), Expect = 0.006
Identities = 38/206 (18%), Positives = 84/206 (40%), Gaps = 5/206 (2%)
Query: 185 STRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAA 244
+ R FPC D + T+ ++ D A+SN +V D + + ++ +
Sbjct: 284 AARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQD-EFSESVKMST 342
Query: 245 SNISLAIGPFEILV-DPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSC 303
++ +G + L D V+ + +P+ + + + ++ EF++ +YP
Sbjct: 343 YLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKK 402
Query: 304 FKTVFIDEAYVEVAAYASMSIFSTNLL---HSAMIIDETPLTRRCLAQSLAQQFFGCFIS 360
V I + + F L + + + L + +A LA Q+FG ++
Sbjct: 403 LDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVT 462
Query: 361 RMSWSDEWVLKGISGYIYGLWMKKTF 386
W+D W+ +G + ++ ++K F
Sbjct: 463 MKWWNDLWLNEGFATFMEYFSLEKIF 488
>gi|32698730 nuclear fragile X mental retardation protein interacting
protein 2 [Homo sapiens]
Length = 695
Score = 40.4 bits (93), Expect = 0.010
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 1143 HSDHHHHHHHEHKKKKKKHKHKH----KHKHKHDSKEKDKEPFTF 1183
H HHH HHH +++++ H H H H H H ++P +
Sbjct: 13 HHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQY 57
Score = 32.3 bits (72), Expect = 2.8
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 16/48 (33%)
Query: 1145 DHHHHHHHEH-------------KKKKKKHKHKHKH---KHKHDSKEK 1176
+HHHHHHH+ K + K KH+ KH +H+ K+K
Sbjct: 44 NHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETPKKK 91
Score = 31.2 bits (69), Expect = 6.2
Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 11/46 (23%)
Query: 1146 HHHHHHHEHKKKKKKHKH-----------KHKHKHKHDSKEKDKEP 1180
H+HHHHH H++ + +H KH+ KH ++ + P
Sbjct: 43 HNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETP 88
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 40.0 bits (92), Expect = 0.013
Identities = 17/34 (50%), Positives = 20/34 (58%)
Query: 1137 ESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHK 1170
+ + S S H HHE +KKK K K KHK KHK
Sbjct: 213 DQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHK 246
Score = 35.4 bits (80), Expect = 0.33
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 1138 STASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSL 1197
S +S HS HH E KK K+K KHK KHK + + T ++ + S + S+
Sbjct: 217 SDSSSHSQDKHHEK-EKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSI 275
Query: 1198 S 1198
S
Sbjct: 276 S 276
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 40.0 bits (92), Expect = 0.013
Identities = 17/34 (50%), Positives = 20/34 (58%)
Query: 1137 ESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHK 1170
+ + S S H HHE +KKK K K KHK KHK
Sbjct: 213 DQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHK 246
Score = 35.4 bits (80), Expect = 0.33
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 1138 STASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSL 1197
S +S HS HH E KK K+K KHK KHK + + T ++ + S + S+
Sbjct: 217 SDSSSHSQDKHHEK-EKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSI 275
Query: 1198 S 1198
S
Sbjct: 276 S 276
>gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]
Length = 356
Score = 39.3 bits (90), Expect = 0.023
Identities = 22/39 (56%), Positives = 24/39 (61%), Gaps = 4/39 (10%)
Query: 1149 HHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPA 1187
H H HKKK KKHK KHK KH +E+D P T SPA
Sbjct: 31 HGHGVHKKKHKKHKKKHKKKH---HQEEDAGP-TQPSPA 65
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 38.9 bits (89), Expect = 0.030
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 10/53 (18%)
Query: 1138 STASKHSDHHHHHHHEHKKKKKKHKHKH-----KHKHK-----HDSKEKDKEP 1180
S +HSDH HH HEH H H + K+K K HDS K+P
Sbjct: 106 SDHERHSDHEHHSDHEHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDP 158
Score = 37.4 bits (85), Expect = 0.086
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 1143 HSDHHHHHHHEHKKKKKKHK-HKHKHKHKHDS 1173
H DH HH HEH ++H H+H H+H S
Sbjct: 93 HHDHDHHSDHEHHSDHERHSDHEHHSDHEHHS 124
Score = 36.2 bits (82), Expect = 0.19
Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 1143 HSDHHHHHHHEHKKKKKKHK-HKHKHKHKHDSKEKDK 1178
HSDH H HEH + H H H H H + K+K
Sbjct: 105 HSDHERHSDHEHHSDHEHHSDHDHHSHHNHAASGKNK 141
Score = 34.7 bits (78), Expect = 0.56
Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 1143 HSDHHHHHHHEHKKKKKKHK-HKHKHKHKHDS 1173
HSDH HH HE + H H+H H H S
Sbjct: 99 HSDHEHHSDHERHSDHEHHSDHEHHSDHDHHS 130
Score = 32.7 bits (73), Expect = 2.1
Identities = 12/36 (33%), Positives = 18/36 (50%)
Query: 1144 SDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKE 1179
SD HHHH++ H H++ H H H + +E
Sbjct: 551 SDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREE 586
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 38.5 bits (88), Expect = 0.039
Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 14/83 (16%)
Query: 1097 PTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHEHKK 1156
P KP L+L K G E L S H + S SDH H E KK
Sbjct: 23 PLEKP---LKLVLKVGGSEVTELSGSGHDS-----------SYYDDRSDHERERHKEKKK 68
Query: 1157 KKKKHKHKHKHKHKHDSKEKDKE 1179
KKKK K KH + +++ +E
Sbjct: 69 KKKKKSEKEKHLDDEERRKRKEE 91
>gi|149408126 nemo like kinase [Homo sapiens]
Length = 527
Score = 38.1 bits (87), Expect = 0.051
Identities = 15/45 (33%), Positives = 20/45 (44%)
Query: 1127 ASAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKH 1171
A+A + T++ + HHHHHHH H H H H H
Sbjct: 8 ANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHH 52
Score = 36.2 bits (82), Expect = 0.19
Identities = 14/34 (41%), Positives = 15/34 (44%)
Query: 1138 STASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKH 1171
S A+ HHHHHH H H H H H H
Sbjct: 21 SAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLH 54
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 38.1 bits (87), Expect = 0.051
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 11/63 (17%)
Query: 1128 SAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKH-----------KHKHKHKHDSKEK 1176
S+ S + + K H +HKK KK KH KHKHK K K K
Sbjct: 1681 SSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1740
Query: 1177 DKE 1179
DKE
Sbjct: 1741 DKE 1743
Score = 37.0 bits (84), Expect = 0.11
Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 13/94 (13%)
Query: 1095 STPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHE- 1153
S+P+ P S +G + S A S K+ KH H H H+
Sbjct: 1660 SSPSVSPSRS----HSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
Query: 1154 --------HKKKKKKHKHKHKHKHKHDSKEKDKE 1179
K +K KHK K K+K KEK+K+
Sbjct: 1716 HAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
Score = 35.8 bits (81), Expect = 0.25
Identities = 35/135 (25%), Positives = 49/135 (36%), Gaps = 35/135 (25%)
Query: 1053 DSQAFISHHLNMLERPSTPGLSKYRPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGT 1112
D+ A + ++ + S+P +S R S + HS+ S S + +K
Sbjct: 1644 DTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAE------SQDSKKKKK 1697
Query: 1113 GKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHH----------HHHEHKKKK-KKH 1161
KE+ K KH H H H+HKKKK KK+
Sbjct: 1698 KKEKK------------------KHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN 1739
Query: 1162 KHKHKHKHKHDSKEK 1176
K K K K K D K K
Sbjct: 1740 KDKEKEKEKDDQKVK 1754
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 38.1 bits (87), Expect = 0.051
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 11/63 (17%)
Query: 1128 SAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKH-----------KHKHKHKHDSKEK 1176
S+ S + + K H +HKK KK KH KHKHK K K K
Sbjct: 1715 SSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1774
Query: 1177 DKE 1179
DKE
Sbjct: 1775 DKE 1777
Score = 37.0 bits (84), Expect = 0.11
Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 13/94 (13%)
Query: 1095 STPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHE- 1153
S+P+ P S +G + S A S K+ KH H H H+
Sbjct: 1694 SSPSVSPSRS----HSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1749
Query: 1154 --------HKKKKKKHKHKHKHKHKHDSKEKDKE 1179
K +K KHK K K+K KEK+K+
Sbjct: 1750 HAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1783
Score = 35.8 bits (81), Expect = 0.25
Identities = 35/135 (25%), Positives = 49/135 (36%), Gaps = 35/135 (25%)
Query: 1053 DSQAFISHHLNMLERPSTPGLSKYRPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGT 1112
D+ A + ++ + S+P +S R S + HS+ S S + +K
Sbjct: 1678 DTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAE------SQDSKKKKK 1731
Query: 1113 GKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHH----------HHHEHKKKK-KKH 1161
KE+ K KH H H H+HKKKK KK+
Sbjct: 1732 KKEKK------------------KHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN 1773
Query: 1162 KHKHKHKHKHDSKEK 1176
K K K K K D K K
Sbjct: 1774 KDKEKEKEKDDQKVK 1788
>gi|13236559 hypothetical protein LOC79169 [Homo sapiens]
Length = 263
Score = 38.1 bits (87), Expect = 0.051
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 14/68 (20%)
Query: 1126 AASAPLSVFTKESTAS--------------KHSDHHHHHHHEHKKKKKKHKHKHKHKHKH 1171
AA LSVFT S + D H+K KK+ K K K KHK
Sbjct: 140 AAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKK 199
Query: 1172 DSKEKDKE 1179
+ K+KDKE
Sbjct: 200 EKKKKDKE 207
Score = 34.3 bits (77), Expect = 0.73
Identities = 17/39 (43%), Positives = 20/39 (51%)
Query: 1150 HHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPAS 1188
H K+KKKK K KHK + K KE + SSP S
Sbjct: 182 HRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTS 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,760,083
Number of Sequences: 37866
Number of extensions: 2120343
Number of successful extensions: 10457
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 7765
Number of HSP's gapped (non-prelim): 1446
length of query: 1199
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1085
effective length of database: 13,930,794
effective search space: 15114911490
effective search space used: 15114911490
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.