Guide to the Human Genome
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Search of human proteins with 4507285

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507285 syntaxin 10 [Homo sapiens]
         (249 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507285 syntaxin 10 [Homo sapiens]                                 485   e-137
gi|5032131 syntaxin 6 [Homo sapiens]                                  303   1e-82
gi|4759188 syntaxin 8 [Homo sapiens]                                   52   5e-07
gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A [...    46   3e-05
gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B [...    44   1e-04
gi|4759184 syntaxin 3 [Homo sapiens]                                   44   2e-04
gi|194353964 coiled-coil domain containing 157 [Homo sapiens]          39   0.004
gi|47778943 syntaxin 16 isoform a [Homo sapiens]                       38   0.007
gi|198041692 syntaxin 16 isoform d [Homo sapiens]                      38   0.007
gi|198041688 syntaxin 16 isoform c [Homo sapiens]                      38   0.007
gi|34447229 syntaxin 16 isoform b [Homo sapiens]                       38   0.007
gi|16262452 cingulin [Homo sapiens]                                    38   0.009
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  36   0.027
gi|33188443 microfilament and actin filament cross-linker protei...    35   0.047
gi|33188445 microfilament and actin filament cross-linker protei...    35   0.047
gi|226495417 coiled-coil domain containing 102A [Homo sapiens]         35   0.080
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    35   0.080
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    35   0.080
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    35   0.080
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    35   0.080
gi|112420968 coiled-coil domain containing 158 [Homo sapiens]          34   0.10 
gi|16418379 syntaxin 1B [Homo sapiens]                                 34   0.14 
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       34   0.14 
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       34   0.14 
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        34   0.14 
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        34   0.14 
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    33   0.18 
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    33   0.18 
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                          33   0.18 
gi|221219020 NYD-SP11 protein [Homo sapiens]                           33   0.23 

>gi|4507285 syntaxin 10 [Homo sapiens]
          Length = 249

 Score =  485 bits (1249), Expect = e-137
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD 60
           MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD
Sbjct: 1   MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD 60

Query: 61  LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR 120
           LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR
Sbjct: 61  LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR 120

Query: 121 EILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHM 180
           EILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHM
Sbjct: 121 EILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHM 180

Query: 181 SGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLL 240
           SGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLL
Sbjct: 181 SGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLL 240

Query: 241 LVLILLFSL 249
           LVLILLFSL
Sbjct: 241 LVLILLFSL 249


>gi|5032131 syntaxin 6 [Homo sapiens]
          Length = 255

 Score =  303 bits (775), Expect = 1e-82
 Identities = 155/255 (60%), Positives = 192/255 (75%), Gaps = 6/255 (2%)

Query: 1   MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD 60
           MS+EDPFFVV+GEVQKAVNTA+GL+QRW ELLQ+ +   REE+DWTTNELRN LRSIEWD
Sbjct: 1   MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD 60

Query: 61  LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR 120
           LEDL+ETI IVEANP KF L A +L  RK F+   R+ V++MKD M + +  A  ER NR
Sbjct: 61  LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR 120

Query: 121 EILAGKPAAQKSPSDL------LDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSI 174
           + L G   +Q   +        LD     A S +IEEQQA QQLI+++QD+QLE+VSGSI
Sbjct: 121 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI 180

Query: 175 QVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAV 234
            VLK+MS R+G EL+EQ +ML+ F+ E++ TQSR+D V++KLAKVSHMTSDRRQWCAIA+
Sbjct: 181 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI 240

Query: 235 LVGVLLLVLILLFSL 249
           L  VLL+VLIL   L
Sbjct: 241 LFAVLLVVLILFLVL 255


>gi|4759188 syntaxin 8 [Homo sapiens]
          Length = 236

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 56/239 (23%), Positives = 103/239 (43%), Gaps = 30/239 (12%)

Query: 25  YQRWCELLQESAAVGREELDWTTNELRNGLRS------IEWDLEDLEETIGIVE------ 72
           Y   C++ QE A    E++       R G ++      I   L++L+E I +++      
Sbjct: 10  YDSTCQIAQEIA----EKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRA 65

Query: 73  ANPGKFKLPAGDLQERKV--FVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQ 130
            +  +     GD ++  +   V R R  +   K+    P  +       R  L  + A +
Sbjct: 66  VSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLI-------RSSLMSEEAKR 118

Query: 131 KSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDE 190
            +P+  L            +E +  QQ I+ EQD  L+ +S  I   K M   +G ELDE
Sbjct: 119 GAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDE 178

Query: 191 QGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLFSL 249
           Q  ++D  A  +++T  ++    R++  V     DR+      ++V +LLLV I++ ++
Sbjct: 179 QNEIIDDLANLVENTDEKLRNETRRVNMV-----DRKSASCGMIMVILLLLVAIVVVAV 232


>gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A
           [Homo sapiens]
          Length = 206

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 15/136 (11%)

Query: 95  MREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQ- 153
           M+EA + +KD  +      F+   N+  L    A +K+  +  D    S  +R ++E++ 
Sbjct: 71  MKEAEKNLKD--LGKCCGLFICPCNK--LKSSDAYKKAWGNNQDGVVASQPARVVDEREQ 126

Query: 154 ----------ATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMD 203
                      T     +E D+ LE VSG I  L+HM+  +G E+D Q   +D   ++ D
Sbjct: 127 MAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKAD 186

Query: 204 HTQSRMDGVLRKLAKV 219
             ++R+D   ++  K+
Sbjct: 187 SNKTRIDEANQRATKM 202


>gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B
           [Homo sapiens]
          Length = 206

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 11/108 (10%)

Query: 123 LAGKPAAQKSPSDLLDASAVSATSRYIEEQQ-----------ATQQLIMDEQDQQLEMVS 171
           L    A +K+  +  D    S  +R ++E++            T     +E D+ LE VS
Sbjct: 95  LKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVS 154

Query: 172 GSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKV 219
           G I  L+HM+  +G E+D Q   +D   ++ D  ++R+D   ++  K+
Sbjct: 155 GIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKM 202


>gi|4759184 syntaxin 3 [Homo sapiens]
          Length = 289

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/219 (22%), Positives = 100/219 (45%), Gaps = 17/219 (7%)

Query: 40  REELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERM-REA 98
           +++L+  T E++    ++   L+ +E+ I   E         + DL+ RK     + R+ 
Sbjct: 74  KDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRS------SADLRIRKSQHSVLSRKF 127

Query: 99  VQEMKDHMVSPTAVAFLERNNREI-----LAGKPAAQKSPSDLLDASAVSATSRYIEEQQ 153
           V+ M  +  +   V F ER+   I     + GK    +   ++L++   +  +  I + Q
Sbjct: 128 VEVMTKY--NEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQ 185

Query: 154 ATQQLIMDEQDQQLEMV--SGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDG 211
            ++Q + + + +  ++V    SI+ L  M   +   ++ QG MLD     + HT   ++ 
Sbjct: 186 ISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEK 245

Query: 212 VLRKLAK-VSHMTSDRRQWCAIAVLVGVLLLVLILLFSL 249
              +  K V + +  R++   I VLV VLL +L L+  L
Sbjct: 246 ARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGL 284


>gi|194353964 coiled-coil domain containing 157 [Homo sapiens]
          Length = 752

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 38/186 (20%), Positives = 86/186 (46%), Gaps = 14/186 (7%)

Query: 12  GEVQKAVNTARGLYQRWCELLQESAAV---GREELDWTTNELRNGLRSIEWDLEDLEETI 68
           G++++A+   +G  +R  E  ++  +     +++L   T++L+  + ++E +L+   E+ 
Sbjct: 312 GKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATLERELKQQREST 371

Query: 69  GIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPA 128
             VEA   + +         +  V+++ E VQ+++  +     V  LE   +++      
Sbjct: 372 QAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQV--QLLVGRLEGAGQQVCWASTE 429

Query: 129 AQKSPSDLLDASAVSATSRYIEEQQATQQLIM---DEQDQQLEMVSGSIQVLKHMSGRVG 185
             K      + + V +  R+ E  QA Q+ ++   D  DQ+ E + GS+   +    RV 
Sbjct: 430 LDK------EKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVE 483

Query: 186 EELDEQ 191
           E+L  +
Sbjct: 484 EQLQSE 489


>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
          Length = 325

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 18/89 (20%), Positives = 48/89 (53%)

Query: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
           L+++E+++++  +  SI  L  +   +G  + EQG +LD     ++ +  + +  L++L 
Sbjct: 231 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 290

Query: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
           K        R+   I +L  ++++++++L
Sbjct: 291 KAEQYQKKNRKMLVILILFVIIIVLIVVL 319


>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
          Length = 308

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 18/89 (20%), Positives = 48/89 (53%)

Query: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
           L+++E+++++  +  SI  L  +   +G  + EQG +LD     ++ +  + +  L++L 
Sbjct: 214 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 273

Query: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
           K        R+   I +L  ++++++++L
Sbjct: 274 KAEQYQKKNRKMLVILILFVIIIVLIVVL 302


>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
          Length = 321

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 18/89 (20%), Positives = 48/89 (53%)

Query: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
           L+++E+++++  +  SI  L  +   +G  + EQG +LD     ++ +  + +  L++L 
Sbjct: 227 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 286

Query: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
           K        R+   I +L  ++++++++L
Sbjct: 287 KAEQYQKKNRKMLVILILFVIIIVLIVVL 315


>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
          Length = 304

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 18/89 (20%), Positives = 48/89 (53%)

Query: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
           L+++E+++++  +  SI  L  +   +G  + EQG +LD     ++ +  + +  L++L 
Sbjct: 210 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 269

Query: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
           K        R+   I +L  ++++++++L
Sbjct: 270 KAEQYQKKNRKMLVILILFVIIIVLIVVL 298


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 37.7 bits (86), Expect = 0.009
 Identities = 47/214 (21%), Positives = 88/214 (41%), Gaps = 15/214 (7%)

Query: 9   VVRGEVQKAVNTARGLYQRWCELLQESA------AVGREELDWTTNELRNGLRSIEWDLE 62
           V+  E QK     RGL +   E  +E+          +E+L  T  EL       E   E
Sbjct: 542 VLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEE 601

Query: 63  DLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREI 122
           +L E I +++    + +  AGD ++ +V  + +    +E+K+           ER ++E+
Sbjct: 602 ELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQA--------ERQSQEV 653

Query: 123 LAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSG 182
            AG+   ++    L      +   R +EEQ    Q  + +  Q  E  S +  V +  + 
Sbjct: 654 -AGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEAT 712

Query: 183 RVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKL 216
            +G+        L    +E D  + R+ G+ ++L
Sbjct: 713 VLGQRRAAVETTLRETQEENDEFRRRILGLEQQL 746


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 36.2 bits (82), Expect = 0.027
 Identities = 31/159 (19%), Positives = 70/159 (44%), Gaps = 11/159 (6%)

Query: 60   DLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNN 119
            +L+ L++ I + E N          L+E +V ++  R  ++++K  + S       ++  
Sbjct: 1546 ELQKLQKDIEMAERNEDHHLQV---LKESEVLLQAKRAELEKLKSQVTS-------QQQE 1595

Query: 120  REILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKH 179
              +L  +   +K    LL  S V A +  ++E     +  + E+   +  V   ++ L  
Sbjct: 1596 MAVLDRQLGHKKEELHLLQGSMVQAKAD-LQEALRLGETEVTEKCNHIREVKSLLEELSF 1654

Query: 180  MSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAK 218
              G +  ++ E+   L    QE++  +  +  VLR+++K
Sbjct: 1655 QKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSK 1693



 Score = 32.3 bits (72), Expect = 0.40
 Identities = 40/204 (19%), Positives = 86/204 (42%), Gaps = 29/204 (14%)

Query: 41   EELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQ 100
            E+L+    +L+  L  +  D   L   I  ++            LQE++  V  ++E + 
Sbjct: 1825 EKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQ----------LQEKREAVNSLQEELA 1874

Query: 101  EMKDHM-VSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLI 159
             ++DH+ ++   +    ++   +L+ +   QK  S+   A+      +  E +Q   Q++
Sbjct: 1875 NVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEW--ANRFEDCQKEEETKQQQLQVL 1932

Query: 160  MDE-QDQQLEMVSGSIQVLKHMSGRVGEE---------LDEQGIMLDAFAQEMDHTQSRM 209
             +E ++ +L++V   +   +    R  EE         L EQ   L+   +E+   +S++
Sbjct: 1933 QNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLE---KELTDQKSKL 1989

Query: 210  DGVLRKLAKVSHMT---SDRRQWC 230
            D VL K+           +  +WC
Sbjct: 1990 DQVLSKVLAAEERVRTLQEEERWC 2013


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 35.4 bits (80), Expect = 0.047
 Identities = 37/184 (20%), Positives = 77/184 (41%), Gaps = 27/184 (14%)

Query: 55   RSIEWDLEDLEETIGIVEAN-PGK--FKLPAGDLQERKVFVERMREAVQEMKDHMVSPTA 111
            +S++  LE L ++IG VE N  GK    L +G +QE      ++++ +   K        
Sbjct: 2550 QSVQESLESLLQSIGEVEQNLEGKQVSSLSSGVIQEALATNMKLKQDIARQKSS------ 2603

Query: 112  VAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVS 171
               LE     +      A  + + +L       + R+  EQ   QQ    E++  L+ + 
Sbjct: 2604 ---LEATREMVTRFMETADSTTAAVLQGKLAEVSQRF--EQLCLQQ---QEKESSLKKLL 2655

Query: 172  GSIQVLKHMSGRVGEELDEQGIMLDA----------FAQEMDHTQSRMDGVLRKLAKVSH 221
               ++ +H+SG++ + ++ +  ML +          F Q++      M+     L  + H
Sbjct: 2656 PQAEMFEHLSGKLQQFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEH 2715

Query: 222  MTSD 225
            + ++
Sbjct: 2716 LVTE 2719


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 35.4 bits (80), Expect = 0.047
 Identities = 37/184 (20%), Positives = 77/184 (41%), Gaps = 27/184 (14%)

Query: 55   RSIEWDLEDLEETIGIVEAN-PGK--FKLPAGDLQERKVFVERMREAVQEMKDHMVSPTA 111
            +S++  LE L ++IG VE N  GK    L +G +QE      ++++ +   K        
Sbjct: 2048 QSVQESLESLLQSIGEVEQNLEGKQVSSLSSGVIQEALATNMKLKQDIARQKSS------ 2101

Query: 112  VAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVS 171
               LE     +      A  + + +L       + R+  EQ   QQ    E++  L+ + 
Sbjct: 2102 ---LEATREMVTRFMETADSTTAAVLQGKLAEVSQRF--EQLCLQQ---QEKESSLKKLL 2153

Query: 172  GSIQVLKHMSGRVGEELDEQGIMLDA----------FAQEMDHTQSRMDGVLRKLAKVSH 221
               ++ +H+SG++ + ++ +  ML +          F Q++      M+     L  + H
Sbjct: 2154 PQAEMFEHLSGKLQQFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEH 2213

Query: 222  MTSD 225
            + ++
Sbjct: 2214 LVTE 2217


>gi|226495417 coiled-coil domain containing 102A [Homo sapiens]
          Length = 550

 Score = 34.7 bits (78), Expect = 0.080
 Identities = 40/182 (21%), Positives = 74/182 (40%), Gaps = 17/182 (9%)

Query: 40  REELDWTTNELRNGLRSI------EWDLEDLEET--IGIVEANPGKFKLPAGDLQERKVF 91
           R  +D    ELR  +  +      EW   +  ET  +G+   N  K +   GDL+E    
Sbjct: 333 RSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENK-KLRAQVGDLEE--AL 389

Query: 92  VERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSA-TSRYIE 150
             R R+    +   + +  A  F    N+E+   K    K      +  A  A  +R +E
Sbjct: 390 ARRRRQTASALDCDLRASQAALF--EKNKELADLKHVHGKLKKQFQEKVAELAHANRRVE 447

Query: 151 EQQATQQ---LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQS 207
           + +A  +   L ++E  ++L      +    + + ++   LDEQ    +    +++H QS
Sbjct: 448 QHEAEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQS 507

Query: 208 RM 209
           R+
Sbjct: 508 RL 509


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 34.7 bits (78), Expect = 0.080
 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 24/187 (12%)

Query: 30   ELLQESAAVGREELDWTTNELRNGLRSIEWDLEDL----EETIGIVEANPGKFKLPAGD- 84
            EL  +SA  GREE      +L+  ++  + +LED     +E     + N  K K    D 
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689

Query: 85   --LQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAV 142
              LQE     ER R+     K+ +    A +         L+G+ A Q     L   + +
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASS---------LSGRNALQDEKRRL--EARI 1738

Query: 143  SATSRYIEEQQATQQLIMD---EQDQQLEMVSGSIQVLKHMSGR---VGEELDEQGIMLD 196
            +     +EE+Q   + + D   +  QQ E +S  +   +  + +     ++L+ Q   L 
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798

Query: 197  AFAQEMD 203
            +   EM+
Sbjct: 1799 SKLHEME 1805



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 52/238 (21%), Positives = 96/238 (40%), Gaps = 28/238 (11%)

Query: 10   VRGEVQKAVNTARGLYQRWCELLQESAAVG---REELDWTTNELRNGLRSIEWDLEDLEE 66
            V G+ ++ V   +   +   + LQ   + G   R EL+   ++L+N + S+   L + E 
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301

Query: 67   TIGIVEANPGKFKLPAGDLQE-------RKVFV-------ERMREAVQEMKDHMVSPTAV 112
                +  +         D QE       +K+ V       E  R ++Q+  D  +   A 
Sbjct: 1302 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME--AK 1359

Query: 113  AFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSG 172
              LER+   +      ++K   D   AS V A    +EE +   Q  ++   QQ E  + 
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDF--ASTVEA----LEEGKKRFQKEIENLTQQYEEKAA 1413

Query: 173  SIQVLKHMSGRVGEELDEQGIMLD---AFAQEMDHTQSRMDGVLRKLAKVSHMTSDRR 227
            +   L+    R+ +ELD+  + LD        ++  Q + D +L +   +S   +D R
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 34.7 bits (78), Expect = 0.080
 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 24/187 (12%)

Query: 30   ELLQESAAVGREELDWTTNELRNGLRSIEWDLEDL----EETIGIVEANPGKFKLPAGD- 84
            EL  +SA  GREE      +L+  ++  + +LED     +E     + N  K K    D 
Sbjct: 1637 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1696

Query: 85   --LQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAV 142
              LQE     ER R+     K+ +    A +         L+G+ A Q     L   + +
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASS---------LSGRNALQDEKRRL--EARI 1745

Query: 143  SATSRYIEEQQATQQLIMD---EQDQQLEMVSGSIQVLKHMSGR---VGEELDEQGIMLD 196
            +     +EE+Q   + + D   +  QQ E +S  +   +  + +     ++L+ Q   L 
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805

Query: 197  AFAQEMD 203
            +   EM+
Sbjct: 1806 SKLHEME 1812



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 52/238 (21%), Positives = 96/238 (40%), Gaps = 28/238 (11%)

Query: 10   VRGEVQKAVNTARGLYQRWCELLQESAAVG---REELDWTTNELRNGLRSIEWDLEDLEE 66
            V G+ ++ V   +   +   + LQ   + G   R EL+   ++L+N + S+   L + E 
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1308

Query: 67   TIGIVEANPGKFKLPAGDLQE-------RKVFV-------ERMREAVQEMKDHMVSPTAV 112
                +  +         D QE       +K+ V       E  R ++Q+  D  +   A 
Sbjct: 1309 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME--AK 1366

Query: 113  AFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSG 172
              LER+   +      ++K   D   AS V A    +EE +   Q  ++   QQ E  + 
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDF--ASTVEA----LEEGKKRFQKEIENLTQQYEEKAA 1420

Query: 173  SIQVLKHMSGRVGEELDEQGIMLD---AFAQEMDHTQSRMDGVLRKLAKVSHMTSDRR 227
            +   L+    R+ +ELD+  + LD        ++  Q + D +L +   +S   +D R
Sbjct: 1421 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1478


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 34.7 bits (78), Expect = 0.080
 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 24/187 (12%)

Query: 30   ELLQESAAVGREELDWTTNELRNGLRSIEWDLEDL----EETIGIVEANPGKFKLPAGD- 84
            EL  +SA  GREE      +L+  ++  + +LED     +E     + N  K K    D 
Sbjct: 1637 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1696

Query: 85   --LQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAV 142
              LQE     ER R+     K+ +    A +         L+G+ A Q     L   + +
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASS---------LSGRNALQDEKRRL--EARI 1745

Query: 143  SATSRYIEEQQATQQLIMD---EQDQQLEMVSGSIQVLKHMSGR---VGEELDEQGIMLD 196
            +     +EE+Q   + + D   +  QQ E +S  +   +  + +     ++L+ Q   L 
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805

Query: 197  AFAQEMD 203
            +   EM+
Sbjct: 1806 SKLHEME 1812



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 52/238 (21%), Positives = 96/238 (40%), Gaps = 28/238 (11%)

Query: 10   VRGEVQKAVNTARGLYQRWCELLQESAAVG---REELDWTTNELRNGLRSIEWDLEDLEE 66
            V G+ ++ V   +   +   + LQ   + G   R EL+   ++L+N + S+   L + E 
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1308

Query: 67   TIGIVEANPGKFKLPAGDLQE-------RKVFV-------ERMREAVQEMKDHMVSPTAV 112
                +  +         D QE       +K+ V       E  R ++Q+  D  +   A 
Sbjct: 1309 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME--AK 1366

Query: 113  AFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSG 172
              LER+   +      ++K   D   AS V A    +EE +   Q  ++   QQ E  + 
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDF--ASTVEA----LEEGKKRFQKEIENLTQQYEEKAA 1420

Query: 173  SIQVLKHMSGRVGEELDEQGIMLD---AFAQEMDHTQSRMDGVLRKLAKVSHMTSDRR 227
            +   L+    R+ +ELD+  + LD        ++  Q + D +L +   +S   +D R
Sbjct: 1421 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1478


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 34.7 bits (78), Expect = 0.080
 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 24/187 (12%)

Query: 30   ELLQESAAVGREELDWTTNELRNGLRSIEWDLEDL----EETIGIVEANPGKFKLPAGD- 84
            EL  +SA  GREE      +L+  ++  + +LED     +E     + N  K K    D 
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689

Query: 85   --LQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAV 142
              LQE     ER R+     K+ +    A +         L+G+ A Q     L   + +
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASS---------LSGRNALQDEKRRL--EARI 1738

Query: 143  SATSRYIEEQQATQQLIMD---EQDQQLEMVSGSIQVLKHMSGR---VGEELDEQGIMLD 196
            +     +EE+Q   + + D   +  QQ E +S  +   +  + +     ++L+ Q   L 
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798

Query: 197  AFAQEMD 203
            +   EM+
Sbjct: 1799 SKLHEME 1805



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 52/238 (21%), Positives = 96/238 (40%), Gaps = 28/238 (11%)

Query: 10   VRGEVQKAVNTARGLYQRWCELLQESAAVG---REELDWTTNELRNGLRSIEWDLEDLEE 66
            V G+ ++ V   +   +   + LQ   + G   R EL+   ++L+N + S+   L + E 
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301

Query: 67   TIGIVEANPGKFKLPAGDLQE-------RKVFV-------ERMREAVQEMKDHMVSPTAV 112
                +  +         D QE       +K+ V       E  R ++Q+  D  +   A 
Sbjct: 1302 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME--AK 1359

Query: 113  AFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSG 172
              LER+   +      ++K   D   AS V A    +EE +   Q  ++   QQ E  + 
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDF--ASTVEA----LEEGKKRFQKEIENLTQQYEEKAA 1413

Query: 173  SIQVLKHMSGRVGEELDEQGIMLD---AFAQEMDHTQSRMDGVLRKLAKVSHMTSDRR 227
            +   L+    R+ +ELD+  + LD        ++  Q + D +L +   +S   +D R
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471


>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
          Length = 1113

 Score = 34.3 bits (77), Expect = 0.10
 Identities = 28/161 (17%), Positives = 74/161 (45%), Gaps = 6/161 (3%)

Query: 30  ELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQE-- 87
           E+L+ +     EE++ TTN+L+  L+S + +LE    T+  +E + G     A  +Q+  
Sbjct: 677 EVLKRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI 736

Query: 88  --RKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLL--DASAVS 143
             ++  ++ ++  +Q +++ M +        +  +  L+ + +   +  + +  +   + 
Sbjct: 737 TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLR 796

Query: 144 ATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRV 184
           +  R ++E+    ++ +D+   Q       IQ  +  S R+
Sbjct: 797 SQERRLKEKVTNMEVALDKASLQFAECQDIIQRQEQESVRL 837


>gi|16418379 syntaxin 1B [Homo sapiens]
          Length = 288

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 43/206 (20%), Positives = 95/206 (46%), Gaps = 19/206 (9%)

Query: 46  TTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERM-REAVQEMKD 104
           T N++R+ L++IE  +E  E                + DL+ RK     + R+ V+ M +
Sbjct: 84  TANKVRSKLKAIEQSIEQEEG-----------LNRSSADLRIRKTQHSTLSRKFVEVMTE 132

Query: 105 HMVSPTAVA--FLERNNREI-LAGKPAAQKSPSDLLDASAVSATSRYIE-EQQATQQLIM 160
           +  + +       +R  R++ + G+    +   D+L++  ++  +  I+ + Q T+Q + 
Sbjct: 133 YNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALN 192

Query: 161 DEQDQQLEMVS--GSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAK 218
           + + +  E++    SI+ L  M   +   ++ QG M+D     ++H+   ++  +    K
Sbjct: 193 EIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKK 252

Query: 219 -VSHMTSDRRQWCAIAVLVGVLLLVL 243
            V + +  RR+   I +   VL +VL
Sbjct: 253 AVKYQSKARRKKIMIIICCVVLGVVL 278


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 17/184 (9%)

Query: 26  QRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDL 85
           Q W   +QE  A  +  L     E +  L + E  +E++ +T   +E       L     
Sbjct: 125 QEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIE----MATLDKEMA 180

Query: 86  QERKVFVERMREAVQEMKDHMVSPTAV--AFLERNNREILAGK---PAAQKSPSDLLDAS 140
           +ER   +++  EA++E  D + +   +  A +E    +  A        ++  + L DA 
Sbjct: 181 EERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL 240

Query: 141 AVSATSRYIEEQQATQ-QLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFA 199
                    E+Q+  + Q +M++++Q+LE       V++    R+ EEL +    +D   
Sbjct: 241 VRMRDLSSSEKQEHVKLQKLMEKKNQELE-------VVRQQRERLQEELSQAESTIDELK 293

Query: 200 QEMD 203
           +++D
Sbjct: 294 EQVD 297


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 17/184 (9%)

Query: 26  QRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDL 85
           Q W   +QE  A  +  L     E +  L + E  +E++ +T   +E       L     
Sbjct: 239 QEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIE----MATLDKEMA 294

Query: 86  QERKVFVERMREAVQEMKDHMVSPTAV--AFLERNNREILAGK---PAAQKSPSDLLDAS 140
           +ER   +++  EA++E  D + +   +  A +E    +  A        ++  + L DA 
Sbjct: 295 EERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL 354

Query: 141 AVSATSRYIEEQQATQ-QLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFA 199
                    E+Q+  + Q +M++++Q+LE       V++    R+ EEL +    +D   
Sbjct: 355 VRMRDLSSSEKQEHVKLQKLMEKKNQELE-------VVRQQRERLQEELSQAESTIDELK 407

Query: 200 QEMD 203
           +++D
Sbjct: 408 EQVD 411


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 17/184 (9%)

Query: 26  QRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDL 85
           Q W   +QE  A  +  L     E +  L + E  +E++ +T   +E       L     
Sbjct: 125 QEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIE----MATLDKEMA 180

Query: 86  QERKVFVERMREAVQEMKDHMVSPTAV--AFLERNNREILAGK---PAAQKSPSDLLDAS 140
           +ER   +++  EA++E  D + +   +  A +E    +  A        ++  + L DA 
Sbjct: 181 EERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL 240

Query: 141 AVSATSRYIEEQQATQ-QLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFA 199
                    E+Q+  + Q +M++++Q+LE       V++    R+ EEL +    +D   
Sbjct: 241 VRMRDLSSSEKQEHVKLQKLMEKKNQELE-------VVRQQRERLQEELSQAESTIDELK 293

Query: 200 QEMD 203
           +++D
Sbjct: 294 EQVD 297


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 17/184 (9%)

Query: 26  QRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDL 85
           Q W   +QE  A  +  L     E +  L + E  +E++ +T   +E       L     
Sbjct: 259 QEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIE----MATLDKEMA 314

Query: 86  QERKVFVERMREAVQEMKDHMVSPTAV--AFLERNNREILAGK---PAAQKSPSDLLDAS 140
           +ER   +++  EA++E  D + +   +  A +E    +  A        ++  + L DA 
Sbjct: 315 EERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL 374

Query: 141 AVSATSRYIEEQQATQ-QLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFA 199
                    E+Q+  + Q +M++++Q+LE       V++    R+ EEL +    +D   
Sbjct: 375 VRMRDLSSSEKQEHVKLQKLMEKKNQELE-------VVRQQRERLQEELSQAESTIDELK 427

Query: 200 QEMD 203
           +++D
Sbjct: 428 EQVD 431


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 17/154 (11%)

Query: 40  REELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAV 99
           +E+ D    E +  + + + DL+DL+E + +++          GDL E++  +  ++E  
Sbjct: 633 KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQ----------GDLSEKEASLLDLKEHA 682

Query: 100 QEM------KDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQ 153
             +      KD  +    +A LE+   E L  +   +K+    L+A A    S  I+  +
Sbjct: 683 SSLASSGLKKDSRLKTLEIA-LEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLE 741

Query: 154 ATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEE 187
                  DE  +    V   +++LK +     ++
Sbjct: 742 REITRYKDESSKAQAEVDRLLEILKEVENEKNDK 775


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 17/154 (11%)

Query: 40  REELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAV 99
           +E+ D    E +  + + + DL+DL+E + +++          GDL E++  +  ++E  
Sbjct: 605 KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQ----------GDLSEKEASLLDLKEHA 654

Query: 100 QEM------KDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQ 153
             +      KD  +    +A LE+   E L  +   +K+    L+A A    S  I+  +
Sbjct: 655 SSLASSGLKKDSRLKTLEIA-LEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLE 713

Query: 154 ATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEE 187
                  DE  +    V   +++LK +     ++
Sbjct: 714 REITRYKDESSKAQAEVDRLLEILKEVENEKNDK 747


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 44/203 (21%), Positives = 88/203 (43%), Gaps = 13/203 (6%)

Query: 46  TTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDH 105
           T N++R+ L+SIE  +E  EE +    A+    K     L  +  FVE M E      D+
Sbjct: 85  TANKVRSKLKSIEQSIEQ-EEGLNRSSADLRIRKTQHSTLSRK--FVEVMSEYNATQSDY 141

Query: 106 MVSPTAVAFLERNNREI-LAGKPAAQKSPSDLLDASAVSA-TSRYIEEQQATQQLIMDEQ 163
                      R  R++ + G+    +   D+L++   +   S  I +   ++Q + + +
Sbjct: 142 RERCKG-----RIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIE 196

Query: 164 DQQLEMVS--GSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAK-VS 220
            +  E++    SI+ L  M   +   ++ QG M+D     ++H    ++  +    K V 
Sbjct: 197 TRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVK 256

Query: 221 HMTSDRRQWCAIAVLVGVLLLVL 243
           + +  RR+   I +   +L +V+
Sbjct: 257 YQSKARRKKIMIIICCVILGIVI 279


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 33.1 bits (74), Expect = 0.23
 Identities = 19/77 (24%), Positives = 31/77 (40%)

Query: 41   EELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQ 100
            + LDW   EL   L  +EWD+E+L      +    GK       L E +  +   RE + 
Sbjct: 1705 QNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLS 1764

Query: 101  EMKDHMVSPTAVAFLER 117
            E +  +     +   E+
Sbjct: 1765 EEETKLAQEEELLIQEK 1781


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,320,566
Number of Sequences: 37866
Number of extensions: 352157
Number of successful extensions: 1503
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 1393
Number of HSP's gapped (non-prelim): 203
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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