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Search of human proteins with 4506575
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506575 retinal outer segment membrane protein 1 [Homo
sapiens]
(351 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506575 retinal outer segment membrane protein 1 [Homo sapiens] 720 0.0
gi|118572596 peripherin 2 [Homo sapiens] 233 1e-61
gi|119120834 tetraspanin 10 [Homo sapiens] 53 5e-07
gi|87159824 CD151 antigen [Homo sapiens] 50 2e-06
gi|87159822 CD151 antigen [Homo sapiens] 50 2e-06
gi|21237751 CD151 antigen [Homo sapiens] 50 2e-06
gi|21237748 CD151 antigen [Homo sapiens] 50 2e-06
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ... 49 5e-06
gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo... 49 9e-06
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens] 40 0.003
gi|30425534 tetraspanin 33 [Homo sapiens] 39 0.007
gi|122937466 tetraspanin 11 [Homo sapiens] 35 0.077
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens] 34 0.22
gi|5729941 tetraspanin 9 [Homo sapiens] 33 0.29
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens] 33 0.29
gi|239756268 PREDICTED: hypothetical protein XP_002344877 [Homo ... 33 0.50
gi|239745177 PREDICTED: hypothetical protein XP_002343381 [Homo ... 33 0.50
gi|239755121 PREDICTED: hypothetical protein [Homo sapiens] 32 1.1
gi|239749649 PREDICTED: hypothetical protein [Homo sapiens] 32 1.1
gi|239743922 PREDICTED: hypothetical protein XP_002342991 [Homo ... 32 1.1
gi|68800005 tetraspanin 4 isoform a [Homo sapiens] 32 1.1
gi|4507543 tetraspanin 4 isoform a [Homo sapiens] 32 1.1
gi|68800018 tetraspanin 4 isoform a [Homo sapiens] 32 1.1
gi|68800024 tetraspanin 4 isoform a [Homo sapiens] 32 1.1
gi|68800011 tetraspanin 4 isoform a [Homo sapiens] 32 1.1
gi|68799997 tetraspanin 4 isoform a [Homo sapiens] 32 1.1
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens] 31 1.5
gi|61966713 DDB1 and CUL4 associated factor 12-like 2 [Homo sapi... 31 1.9
gi|198041678 solute carrier family 12 (potassium-chloride transp... 31 1.9
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 31 1.9
>gi|4506575 retinal outer segment membrane protein 1 [Homo sapiens]
Length = 351
Score = 720 bits (1858), Expect = 0.0
Identities = 351/351 (100%), Positives = 351/351 (100%)
Query: 1 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFP 60
MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFP
Sbjct: 1 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFP 60
Query: 61 VLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALG 120
VLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALG
Sbjct: 61 VLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALG 120
Query: 121 LALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
LALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV
Sbjct: 121 LALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
Query: 181 QWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFD 240
QWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFD
Sbjct: 181 QWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFD 240
Query: 241 PRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVI 300
PRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVI
Sbjct: 241 PRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVI 300
Query: 301 DAGGETQGYLFPSGLKDMLKTAWLQGGVACRPAPEEAPPGEAPPKEDLSEA 351
DAGGETQGYLFPSGLKDMLKTAWLQGGVACRPAPEEAPPGEAPPKEDLSEA
Sbjct: 301 DAGGETQGYLFPSGLKDMLKTAWLQGGVACRPAPEEAPPGEAPPKEDLSEA 351
>gi|118572596 peripherin 2 [Homo sapiens]
Length = 346
Score = 233 bits (595), Expect = 1e-61
Identities = 123/334 (36%), Positives = 193/334 (57%), Gaps = 7/334 (2%)
Query: 14 RIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVA 73
R++LAQGLWL++W LAG +I L ++LR + S + +P + + G ++
Sbjct: 13 RVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIELRKRSDVMNNS-ESHFVPNSLIGMGVLS 71
Query: 74 LGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEAL 133
+ +L+ A Y W+ L P L L +VAL L L GSL+ L
Sbjct: 72 CVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALCCFL-LRGSLENTL 130
Query: 134 EEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDR 193
+GL + +Y+DT+ PG C K+ +D LQ+ + CCG +G++DWF +QW+S+RYLD +
Sbjct: 131 GQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSK 190
Query: 194 DVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFDPRQPNQNLWAQGC 253
+V DRI+SNV+G YL DGVPFSCCNP SPRPC+Q +++++ AH +D + NLW +GC
Sbjct: 191 EVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGC 250
Query: 254 HEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVIDAGGETQGYLFPS 313
LL + L ++G + + +L + + +GLRYLQT+L+G+ ++ E+QG+L
Sbjct: 251 RAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESQGWLLER 310
Query: 314 GLKDMLKTAWLQG----GVACRPAPEEAPPGEAP 343
+ + K A+L+ G + E A G+AP
Sbjct: 311 SVPETWK-AFLESVKKLGKGNQVEAEGADAGQAP 343
>gi|119120834 tetraspanin 10 [Homo sapiens]
Length = 355
Score = 52.8 bits (125), Expect = 5e-07
Identities = 65/227 (28%), Positives = 96/227 (42%), Gaps = 43/227 (18%)
Query: 74 LGTGLVGVGASRASLNAALYPPWRGVLGPL-----LVAGTAGGG----GLLVVALGLALA 124
LG L G+ S SL G LG L L+ G +GG L VA L +A
Sbjct: 122 LGLALGGLVVSAVSL--------AGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVA 173
Query: 125 LPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVS 184
L G L ++LE L A+AHY+D + L+D++QL CCG Y+DW Q +
Sbjct: 174 LWGPLQDSLEHTLRVAIAHYQDDP-----DLRFLLDQVQLGLRCCGAASYQDW--QQNLY 226
Query: 185 SRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCC-NPHSPRPCLQNRLSDSYAHPLFDPRQ 243
PG + + +P SCC +P + ++ + D
Sbjct: 227 FNCSSPGVQACS---------------LPASCCIDPREDGASVNDQC--GFGVLRLDADA 269
Query: 244 PNQNLWAQGCHEVLLEHLQ-DLAGTLGSMLAVTFLLQALVLLGLRYL 289
+ ++ +GC L L+ +LA + G +AV L A +LL R L
Sbjct: 270 AQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLL 316
>gi|87159824 CD151 antigen [Homo sapiens]
Length = 253
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 20/183 (10%)
Query: 24 LSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVGVGA 83
L+ L +A G+ L + L GT+LA + + AG V + TG++G A
Sbjct: 29 LAGLAVMAVGIWTLALKSDYISLLASGTYLATA-------YILVVAGTVVMVTGVLGCCA 81
Query: 84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTALAH 143
+ L + +L L L ++A LA A L+ L+E L +
Sbjct: 82 TFKERRNLLRLYFILLLIIFL---------LEIIAGILAYAYYQQLNTELKENLKDTMT- 131
Query: 144 YKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNV 203
K PGH VD+LQ +HCCG + +DW +W+ S+ + G R V D V
Sbjct: 132 -KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQ--EAGGRVVPDSCCKTV 188
Query: 204 EGL 206
L
Sbjct: 189 VAL 191
>gi|87159822 CD151 antigen [Homo sapiens]
Length = 253
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 20/183 (10%)
Query: 24 LSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVGVGA 83
L+ L +A G+ L + L GT+LA + + AG V + TG++G A
Sbjct: 29 LAGLAVMAVGIWTLALKSDYISLLASGTYLATA-------YILVVAGTVVMVTGVLGCCA 81
Query: 84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTALAH 143
+ L + +L L L ++A LA A L+ L+E L +
Sbjct: 82 TFKERRNLLRLYFILLLIIFL---------LEIIAGILAYAYYQQLNTELKENLKDTMT- 131
Query: 144 YKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNV 203
K PGH VD+LQ +HCCG + +DW +W+ S+ + G R V D V
Sbjct: 132 -KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQ--EAGGRVVPDSCCKTV 188
Query: 204 EGL 206
L
Sbjct: 189 VAL 191
>gi|21237751 CD151 antigen [Homo sapiens]
Length = 253
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 20/183 (10%)
Query: 24 LSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVGVGA 83
L+ L +A G+ L + L GT+LA + + AG V + TG++G A
Sbjct: 29 LAGLAVMAVGIWTLALKSDYISLLASGTYLATA-------YILVVAGTVVMVTGVLGCCA 81
Query: 84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTALAH 143
+ L + +L L L ++A LA A L+ L+E L +
Sbjct: 82 TFKERRNLLRLYFILLLIIFL---------LEIIAGILAYAYYQQLNTELKENLKDTMT- 131
Query: 144 YKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNV 203
K PGH VD+LQ +HCCG + +DW +W+ S+ + G R V D V
Sbjct: 132 -KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQ--EAGGRVVPDSCCKTV 188
Query: 204 EGL 206
L
Sbjct: 189 VAL 191
>gi|21237748 CD151 antigen [Homo sapiens]
Length = 253
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 20/183 (10%)
Query: 24 LSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVGVGA 83
L+ L +A G+ L + L GT+LA + + AG V + TG++G A
Sbjct: 29 LAGLAVMAVGIWTLALKSDYISLLASGTYLATA-------YILVVAGTVVMVTGVLGCCA 81
Query: 84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTALAH 143
+ L + +L L L ++A LA A L+ L+E L +
Sbjct: 82 TFKERRNLLRLYFILLLIIFL---------LEIIAGILAYAYYQQLNTELKENLKDTMT- 131
Query: 144 YKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNV 203
K PGH VD+LQ +HCCG + +DW +W+ S+ + G R V D V
Sbjct: 132 -KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQ--EAGGRVVPDSCCKTV 188
Query: 204 EGL 206
L
Sbjct: 189 VAL 191
>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
sapiens]
Length = 253
Score = 49.3 bits (116), Expect = 5e-06
Identities = 50/220 (22%), Positives = 81/220 (36%), Gaps = 50/220 (22%)
Query: 67 LAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALP 126
+A GA+ GL+G A+ L V+ LLV T VV + L
Sbjct: 58 IAVGALLFIIGLIGCCATIRESRCGLAT---FVIILLLVFVTE------VVVVVLGYVYR 108
Query: 127 GSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSR 186
++ ++ + Y T A R +D +Q + HCCG H Y DW W
Sbjct: 109 AKVENEVDRSIQKVYKTYNGTNPDA---ASRAIDYVQRQLHCCGIHNYSDWENTDWFKET 165
Query: 187 YLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFDPRQPNQ 246
VP SCC + + + S AHP
Sbjct: 166 ---------------------KNQSVPLSCCRETA------SNCNGSLAHP--------S 190
Query: 247 NLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGL 286
+L+A+GC ++++ LQ++ + ++ A+ LLG+
Sbjct: 191 DLYAEGCEALVVKKLQEI---MMHVIWAALAFAAIQLLGM 227
>gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo
sapiens]
Length = 228
Score = 48.5 bits (114), Expect = 9e-06
Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 38/132 (28%)
Query: 155 AKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPF 214
A R +D +Q + HCCG H Y DW W VP
Sbjct: 109 ASRAIDYVQRQLHCCGIHNYSDWENTDWFKET---------------------KNQSVPL 147
Query: 215 SCCNPHSPRPCLQNRLSDSYAHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAV 274
SCC + + + S AHP +L+A+GC ++++ LQ++ + ++
Sbjct: 148 SCCRETA------SNCNGSLAHP--------SDLYAEGCEALVVKKLQEI---MMHVIWA 190
Query: 275 TFLLQALVLLGL 286
A+ LLG+
Sbjct: 191 ALAFAAIQLLGM 202
>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
Length = 294
Score = 40.0 bits (92), Expect = 0.003
Identities = 50/201 (24%), Positives = 78/201 (38%), Gaps = 42/201 (20%)
Query: 21 LWLLSWLLALAGGVILLCSGHLLVQLRHLGT----FLAPSCQFPVLPQAALAAGAVALGT 76
L + S + L G ++L + V+ + T FLAP+ +L G V
Sbjct: 24 LIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAIILILL-------GVVMFMV 76
Query: 77 GLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEG 136
+GV AS N L + +LG L+ GG VVAL L++ + G
Sbjct: 77 SFIGVLASLRD-NLYLLQAFMYILGICLIMELIGG----VVALTFRNQTIDFLNDNIRRG 131
Query: 137 LVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVA 196
+ +Y D + K ++D +Q ++ CCG Y+DW Q+ P
Sbjct: 132 IEN---YYDDLDF------KNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGP------ 176
Query: 197 DRIQSNVEGLYLTDGVPFSCC 217
L GVP++CC
Sbjct: 177 -----------LACGVPYTCC 186
>gi|30425534 tetraspanin 33 [Homo sapiens]
Length = 283
Score = 38.9 bits (89), Expect = 0.007
Identities = 31/139 (22%), Positives = 56/139 (40%), Gaps = 22/139 (15%)
Query: 133 LEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGD 192
+ E + A+ HY+D + L+D Q ++ CCG YKDW + + +P
Sbjct: 126 VSEIINNAIVHYRDD-----LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSR 180
Query: 193 RDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFDPRQPNQNLWAQG 252
+ VP+SCC P +P + N + FD + ++ ++ G
Sbjct: 181 ERCS---------------VPYSCCLP-TPDQAVINTMC-GQGMQAFDYLEASKVIYTNG 223
Query: 253 CHEVLLEHLQDLAGTLGSM 271
C + L+ + LG +
Sbjct: 224 CIDKLVNWIHSNLFLLGGV 242
>gi|122937466 tetraspanin 11 [Homo sapiens]
Length = 253
Score = 35.4 bits (80), Expect = 0.077
Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Query: 21 LWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVG 80
L++ ++ + G +L LV+ + LA S F + AG + + TG +G
Sbjct: 20 LFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASST-FAASAYILIFAGVLVMVTGFLG 78
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
GA L + +L LV AG LA L + L++ L
Sbjct: 79 FGAILWERKGCLSTYFCLLLVIFLVELVAGV---------LAHVYYQRLSDELKQHLNRT 129
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDW 177
LA ++ PG Q VD LQ + CCG + DW
Sbjct: 130 LA--ENYGQPGATQITASVDRLQQDFKCCGSNSSADW 164
>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
Length = 1235
Score = 33.9 bits (76), Expect = 0.22
Identities = 32/73 (43%), Positives = 36/73 (49%), Gaps = 14/73 (19%)
Query: 67 LAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGG--------GLLVVA 118
L A +AL GLVG+GAS L AL+ P L LL GTA G GL+ V
Sbjct: 985 LQAALLALEVGLVGLGASYLLLCTALHLP--SSLFLLLAQGTALGAVLGLSWRRGLMGVP 1042
Query: 119 LGLA----LALPG 127
LGL LA PG
Sbjct: 1043 LGLGAAWLLAWPG 1055
>gi|5729941 tetraspanin 9 [Homo sapiens]
Length = 239
Score = 33.5 bits (75), Expect = 0.29
Identities = 59/248 (23%), Positives = 94/248 (37%), Gaps = 61/248 (24%)
Query: 50 GTFLAPSCQFPVLPQAAL--AAGAVALGTGLVG-VGASRASLNAALYPPWRGVLGPLLVA 106
G F S FP L A L A G + + TG +G +GA + N L + VL +L+A
Sbjct: 39 GNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKE--NKCLLLSFFIVLLVILLA 96
Query: 107 GTAGGGGLLVVALGLALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRY 166
LL++ + + + L+EGL L ++ + V K + +Q
Sbjct: 97 ELI----LLILFFVYMDKVNENAKKDLKEGL---LLYHTENNVG----LKNAWNIIQAEM 145
Query: 167 HCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCL 226
CCG Y DW+ V G+ V DR CC +S + C
Sbjct: 146 RCCGVTDYTDWYPVL---------GENTVPDR-----------------CCMENS-QGCG 178
Query: 227 QNRLSDSYAHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGL 286
+N + LW GC+E + D LG++ ++Q +LG+
Sbjct: 179 RNATTP---------------LWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQ---ILGM 220
Query: 287 RYLQTALE 294
+ T +
Sbjct: 221 AFSMTLFQ 228
>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
Length = 270
Score = 33.5 bits (75), Expect = 0.29
Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 23/144 (15%)
Query: 156 KRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTD---GV 212
+ L+D LQ CCG +G +DW D+ + N G + GV
Sbjct: 141 QNLIDSLQKANQCCGAYGPEDW----------------DL--NVYFNCSGASYSREKCGV 182
Query: 213 PFSCCNPHSPRPCLQNRLSDSYAHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSML 272
PFSCC P + + + Y + + +++++ +GC + L L + +
Sbjct: 183 PFSCCVPDPAQKVVNTQC--GYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVF 240
Query: 273 AVTFLLQALVLLGLRYLQTALEGL 296
LLQ + R L + +E +
Sbjct: 241 IAISLLQIFGIFLARTLISDIEAV 264
>gi|239756268 PREDICTED: hypothetical protein XP_002344877 [Homo
sapiens]
Length = 252
Score = 32.7 bits (73), Expect = 0.50
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 60 PVLPQAALAAGAVALGTGLVGVG-----ASR--ASLNAALYPPWRGVLGPLLVAGTAGGG 112
P P A AAG LG+G +G+G A+R A+ A PPW+G G G GG
Sbjct: 168 PRAPPPAPAAGQRGLGSGALGLGRREKLAARPAATPRRASRPPWQGCRG---ARGLGGGR 224
Query: 113 GLL 115
G L
Sbjct: 225 GPL 227
>gi|239745177 PREDICTED: hypothetical protein XP_002343381 [Homo
sapiens]
Length = 252
Score = 32.7 bits (73), Expect = 0.50
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 60 PVLPQAALAAGAVALGTGLVGVG-----ASR--ASLNAALYPPWRGVLGPLLVAGTAGGG 112
P P A AAG LG+G +G+G A+R A+ A PPW+G G G GG
Sbjct: 168 PRAPPPAPAAGQRGLGSGALGLGRREKLAARPAATPRRASRPPWQGCRG---ARGLGGGR 224
Query: 113 GLL 115
G L
Sbjct: 225 GPL 227
>gi|239755121 PREDICTED: hypothetical protein [Homo sapiens]
Length = 339
Score = 31.6 bits (70), Expect = 1.1
Identities = 31/104 (29%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 65 AALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALA 124
A L A A LVG+G + + PW +G GGGG V ALG L
Sbjct: 127 AVLRAPTDAEAQALVGLGTPQTH---QAHLPWPRAVGAAPGGLPVGGGGGQVEALGRVLV 183
Query: 125 ---LPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLR 165
L G+ D+ + G L D V H Q V+++ R
Sbjct: 184 EEQLVGARDDQTKHGQQAPL----DRTVQQHAQGAHQVEDVAAR 223
>gi|239749649 PREDICTED: hypothetical protein [Homo sapiens]
Length = 339
Score = 31.6 bits (70), Expect = 1.1
Identities = 31/104 (29%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 65 AALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALA 124
A L A A LVG+G + + PW +G GGGG V ALG L
Sbjct: 127 AVLRAPTDAEAQALVGLGTPQTH---QAHLPWPRAVGAAPGGLPVGGGGGQVEALGRVLV 183
Query: 125 ---LPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLR 165
L G+ D+ + G L D V H Q V+++ R
Sbjct: 184 EEQLVGARDDQTKHGQQAPL----DRTVQQHAQGAHQVEDVAAR 223
>gi|239743922 PREDICTED: hypothetical protein XP_002342991 [Homo
sapiens]
Length = 339
Score = 31.6 bits (70), Expect = 1.1
Identities = 31/104 (29%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 65 AALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALA 124
A L A A LVG+G + + PW +G GGGG V ALG L
Sbjct: 127 AVLRAPTDAEAQALVGLGTPQTH---QAHLPWPRAVGAAPGGLPVGGGGGQVEALGRVLV 183
Query: 125 ---LPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLR 165
L G+ D+ + G L D V H Q V+++ R
Sbjct: 184 EEQLVGARDDQTKHGQQAPL----DRTVQQHAQGAHQVEDVAAR 223
>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 23 LLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALA--AGAVALGTGLVG 80
LL WL GG +L G L + G+F S FP L A L GA + G VG
Sbjct: 18 LLFWL----GGCGVLGVGIWLAATQ--GSFATLSSSFPSLSAANLLIITGAFVMAIGFVG 71
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
+ L + +L L+ T +A+ L A +D ++ L
Sbjct: 72 CLGAIKENKCLLLTFFLLLLLVFLLEAT--------IAI-LFFAYTDKIDRYAQQDLKKG 122
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
L Y G A ++ Q + CCG Y DWF V
Sbjct: 123 LHLYGTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFEV 159
>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 23 LLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALA--AGAVALGTGLVG 80
LL WL GG +L G L + G+F S FP L A L GA + G VG
Sbjct: 18 LLFWL----GGCGVLGVGIWLAATQ--GSFATLSSSFPSLSAANLLIITGAFVMAIGFVG 71
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
+ L + +L L+ T +A+ L A +D ++ L
Sbjct: 72 CLGAIKENKCLLLTFFLLLLLVFLLEAT--------IAI-LFFAYTDKIDRYAQQDLKKG 122
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
L Y G A ++ Q + CCG Y DWF V
Sbjct: 123 LHLYGTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFEV 159
>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 23 LLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALA--AGAVALGTGLVG 80
LL WL GG +L G L + G+F S FP L A L GA + G VG
Sbjct: 18 LLFWL----GGCGVLGVGIWLAATQ--GSFATLSSSFPSLSAANLLIITGAFVMAIGFVG 71
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
+ L + +L L+ T +A+ L A +D ++ L
Sbjct: 72 CLGAIKENKCLLLTFFLLLLLVFLLEAT--------IAI-LFFAYTDKIDRYAQQDLKKG 122
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
L Y G A ++ Q + CCG Y DWF V
Sbjct: 123 LHLYGTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFEV 159
>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 23 LLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALA--AGAVALGTGLVG 80
LL WL GG +L G L + G+F S FP L A L GA + G VG
Sbjct: 18 LLFWL----GGCGVLGVGIWLAATQ--GSFATLSSSFPSLSAANLLIITGAFVMAIGFVG 71
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
+ L + +L L+ T +A+ L A +D ++ L
Sbjct: 72 CLGAIKENKCLLLTFFLLLLLVFLLEAT--------IAI-LFFAYTDKIDRYAQQDLKKG 122
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
L Y G A ++ Q + CCG Y DWF V
Sbjct: 123 LHLYGTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFEV 159
>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 23 LLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALA--AGAVALGTGLVG 80
LL WL GG +L G L + G+F S FP L A L GA + G VG
Sbjct: 18 LLFWL----GGCGVLGVGIWLAATQ--GSFATLSSSFPSLSAANLLIITGAFVMAIGFVG 71
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
+ L + +L L+ T +A+ L A +D ++ L
Sbjct: 72 CLGAIKENKCLLLTFFLLLLLVFLLEAT--------IAI-LFFAYTDKIDRYAQQDLKKG 122
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
L Y G A ++ Q + CCG Y DWF V
Sbjct: 123 LHLYGTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFEV 159
>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 23 LLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALA--AGAVALGTGLVG 80
LL WL GG +L G L + G+F S FP L A L GA + G VG
Sbjct: 18 LLFWL----GGCGVLGVGIWLAATQ--GSFATLSSSFPSLSAANLLIITGAFVMAIGFVG 71
Query: 81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALGLALALPGSLDEALEEGLVTA 140
+ L + +L L+ T +A+ L A +D ++ L
Sbjct: 72 CLGAIKENKCLLLTFFLLLLLVFLLEAT--------IAI-LFFAYTDKIDRYAQQDLKKG 122
Query: 141 LAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 180
L Y G A ++ Q + CCG Y DWF V
Sbjct: 123 LHLYGTQGNVGLTNAWSII---QTDFRCCGVSNYTDWFEV 159
>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
Length = 245
Score = 31.2 bits (69), Expect = 1.5
Identities = 11/28 (39%), Positives = 16/28 (57%)
Query: 159 VDELQLRYHCCGRHGYKDWFGVQWVSSR 186
VD++Q HCCG Y+DW + S +
Sbjct: 144 VDKIQNTLHCCGVTDYRDWTDTNYYSEK 171
>gi|61966713 DDB1 and CUL4 associated factor 12-like 2 [Homo
sapiens]
Length = 463
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Query: 168 CCG-RHGYKDW-FGVQWVSSRYLDPGDRD 194
C G RHG+KDW F V W+S G RD
Sbjct: 186 CLGDRHGHKDWIFAVAWLSDTVAVSGSRD 214
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 30.8 bits (68), Expect = 1.9
Identities = 31/133 (23%), Positives = 52/133 (39%), Gaps = 19/133 (14%)
Query: 24 LSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVGVGA 83
L+W++ +AG + C F+ SC A++ A+A G+V G
Sbjct: 143 LTWVVGIAGIMESFCM-----------VFICCSCTM----LTAISMSAIATN-GVVPAGG 186
Query: 84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLV---VALGLALALPGSLDEALEEGLVTA 140
S ++ +L P + G +G GT G + + + + LA P E+ A
Sbjct: 187 SYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASGEA 246
Query: 141 LAHYKDTEVPGHC 153
A + V G C
Sbjct: 247 AAMLNNMRVYGTC 259
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 30.8 bits (68), Expect = 1.9
Identities = 31/133 (23%), Positives = 52/133 (39%), Gaps = 19/133 (14%)
Query: 24 LSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVGVGA 83
L+W++ +AG + C F+ SC A++ A+A G+V G
Sbjct: 120 LTWVVGIAGIMESFCM-----------VFICCSCTM----LTAISMSAIATN-GVVPAGG 163
Query: 84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLV---VALGLALALPGSLDEALEEGLVTA 140
S ++ +L P + G +G GT G + + + + LA P E+ A
Sbjct: 164 SYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASGEA 223
Query: 141 LAHYKDTEVPGHC 153
A + V G C
Sbjct: 224 AAMLNNMRVYGTC 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.141 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,487,715
Number of Sequences: 37866
Number of extensions: 753763
Number of successful extensions: 2575
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 2535
Number of HSP's gapped (non-prelim): 67
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.