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Search of human proteins with 4506263
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
sapiens]
(386 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo s... 779 0.0
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom... 250 2e-66
gi|28466969 prostaglandin D2 receptor [Homo sapiens] 224 1e-58
gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens] 183 2e-46
gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [H... 132 4e-31
gi|4507381 thromboxane A2 receptor [Homo sapiens] 130 2e-30
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 128 1e-29
gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H... 128 1e-29
gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 128 1e-29
gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [H... 128 1e-29
gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [H... 128 1e-29
gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [H... 128 1e-29
gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 128 1e-29
gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [H... 128 1e-29
gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4 [... 128 1e-29
gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens] 114 2e-25
gi|4506261 prostaglandin F receptor isoform a precursor [Homo sa... 110 2e-24
gi|88758606 prostaglandin F receptor isoform b precursor [Homo s... 82 6e-16
gi|149944554 somatostatin receptor 4 [Homo sapiens] 59 6e-09
gi|188497623 neuromedin U receptor 1 [Homo sapiens] 57 2e-08
gi|4557865 somatostatin receptor 5 [Homo sapiens] 56 6e-08
gi|4885299 G protein-coupled receptor 15 [Homo sapiens] 56 6e-08
gi|9506747 G protein-coupled receptor 27 [Homo sapiens] 55 8e-08
gi|4503907 galanin receptor 3 [Homo sapiens] 55 1e-07
gi|9789897 leukotriene B4 receptor 2 [Homo sapiens] 54 2e-07
gi|89353783 coagulation factor II (thrombin) receptor-like 3 pre... 54 2e-07
gi|5730019 peropsin [Homo sapiens] 54 2e-07
gi|167000885 galanin receptor 1 [Homo sapiens] 52 9e-07
gi|55953085 G protein-coupled receptor 120 [Homo sapiens] 52 9e-07
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens] 52 1e-06
>gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
sapiens]
Length = 386
Score = 779 bits (2011), Expect = 0.0
Identities = 386/386 (100%), Positives = 386/386 (100%)
Query: 1 MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD 60
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
Sbjct: 1 MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD 60
Query: 61 LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA 120
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
Sbjct: 61 LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA 120
Query: 121 LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG 180
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
Sbjct: 121 LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG 180
Query: 181 GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL 240
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
Sbjct: 181 GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL 240
Query: 241 LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF 300
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
Sbjct: 241 LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF 300
Query: 301 QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL 360
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
Sbjct: 301 QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL 360
Query: 361 PPTQQSSGSAVGTSSKAEASVACSLC 386
PPTQQSSGSAVGTSSKAEASVACSLC
Sbjct: 361 PPTQQSSGSAVGTSSKAEASVACSLC 386
>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
sapiens]
Length = 358
Score = 250 bits (638), Expect = 2e-66
Identities = 149/331 (45%), Positives = 194/331 (58%), Gaps = 31/331 (9%)
Query: 2 ADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGIL----------SARRPARPSAFAV 51
++ C ++ PA S++MF AGV+GN +AL +L SA R + S F V
Sbjct: 10 SEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHV 69
Query: 52 LVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILF 111
LVT L TDLLGT +SP V +YARN +L+ LA A C FAFAMTFF LA+ML+LF
Sbjct: 70 LVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTFFSLATMLMLF 128
Query: 112 AMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCF 171
AMA+ER L++ HPY Y + LP IYA +LFC+LPLL GQ+ QYCPG+WCF
Sbjct: 129 AMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCF 188
Query: 172 LRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQ-------GSL 224
+R G A+ YA L+ LL+ ++ CN SV L+L RM+R+ +R + G
Sbjct: 189 IR-----HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRG 243
Query: 225 GP-RPRTGE-----DEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAF 278
GP R GE +E DHLILLA+MT+ AVCSLP TI F S E DL A
Sbjct: 244 GPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTI--FAYMNETSSRKEKWDLQAL 301
Query: 279 RFYAFNPILDPWVFILFRKAVFQRLKLWVCC 309
RF + N I+DPWVF + R V + ++ +CC
Sbjct: 302 RFLSINSIIDPWVFAILRPPVLRLMRSVLCC 332
>gi|28466969 prostaglandin D2 receptor [Homo sapiens]
Length = 359
Score = 224 bits (571), Expect = 1e-58
Identities = 139/325 (42%), Positives = 186/325 (57%), Gaps = 28/325 (8%)
Query: 5 CRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILS-------ARRPARP--SAFAVLVTG 55
C+N T V ++F G++GN LALG+L+ +RRP RP S F +LV G
Sbjct: 8 CQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCG 67
Query: 56 LAATDLLGTSFLSPAVFVAYARNSSLLGLARG-GPALCDAFAFAMTFFGLASMLILFAMA 114
L TDLLG LSP V AYA+N SL LA +LC AFAF M+FFGL+S L L AMA
Sbjct: 68 LTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMA 127
Query: 115 VERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM 174
+E L+L HP+ Y + R L P + AF + FCALP +G G+ QYCPG+WCF++M
Sbjct: 128 LECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQM 187
Query: 175 RWAQPGGA--AFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGS-----LGPR 227
+ + +S+ Y+ L+ALLV A LCN +L M+R+ +RH S PR
Sbjct: 188 VHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPR 247
Query: 228 PRTGE------DEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAP-----DSSSEMGDLL 276
E +E+DHL+LLALMTV+ +CSLP+ R + A +S E DL
Sbjct: 248 ADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLR 307
Query: 277 AFRFYAFNPILDPWVFILFRKAVFQ 301
A RF + I+DPW+FI+FR VF+
Sbjct: 308 ALRFLSVISIVDPWIFIIFRSPVFR 332
>gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens]
Length = 488
Score = 183 bits (465), Expect = 2e-46
Identities = 119/327 (36%), Positives = 165/327 (50%), Gaps = 43/327 (13%)
Query: 22 LMFVAGVVGNGLALGIL-SARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSS 80
+MF+ GVVGN +A+ +L +R+ + + F LV GLA TDLLGT +SP Y +
Sbjct: 26 VMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMK--- 82
Query: 81 LLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLAL 140
G GG LC+ F + FF L+ + I+ AM+VER LA++H Y Y+ R A L L
Sbjct: 83 --GQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTL 140
Query: 141 PAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIF 200
A+YA VLFCALP +GLG + P +WCF+ AA+S YAG + L+ A
Sbjct: 141 FAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATV 200
Query: 201 LCNGSVTLSLCRMYRQQKR---------------------HQGSLGPRPRTGE------- 232
LCN V +L RM+RQ R H + PR +
Sbjct: 201 LCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSF 260
Query: 233 -----DEVDHLILLALMTVVMAVCSLPLTIRCF-TQAVAPDSSSEMG---DLLAFRFYAF 283
E+ +ILL ++V+ +CS+PL +R F Q P E+ DL A R +
Sbjct: 261 RRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASV 320
Query: 284 NPILDPWVFILFRKAVFQRLKLWVCCL 310
NPILDPW++IL RK V + + CL
Sbjct: 321 NPILDPWIYILLRKTVLSKAIEKIKCL 347
>gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [Homo
sapiens]
Length = 393
Score = 132 bits (333), Expect = 4e-31
Identities = 108/352 (30%), Positives = 153/352 (43%), Gaps = 43/352 (12%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQRLKLWVCCLCLGP-----AHGDSQTPLSQLASGRRDP 333
LDPWV++L RK + ++ C +GP H Q P + +S R+P
Sbjct: 341 LDPWVYLLLRKILLRKF-----CQEMGPDGRCFCHAWRQVPRTWCSSHDREP 387
>gi|4507381 thromboxane A2 receptor [Homo sapiens]
Length = 343
Score = 130 bits (327), Expect = 2e-30
Identities = 100/293 (34%), Positives = 144/293 (49%), Gaps = 21/293 (7%)
Query: 25 VAGVVGNGLALGILSARRPARP---SAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSL 81
V G+ N LAL +L+ R S+F + GL TD LG V +A
Sbjct: 36 VVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEW 95
Query: 82 LGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALP 141
+ G LC M FFGL+ +L+ AMA ER L ++ P+ + R A +
Sbjct: 96 HAVDPGC-RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVG 154
Query: 142 AIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFL 201
++A + LPLLG+G++ PGSWCFL + A+ G AF L ++ L L V FL
Sbjct: 155 LVWAAALALGLLPLLGVGRYTVQYPGSWCFLTL-GAESGDVAFGLLFSMLGGLSVGLSFL 213
Query: 202 CNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPL------ 255
N +LC +Y Q+ Q RPR + EV+ + L + VV +VC LPL
Sbjct: 214 LNTVSVATLCHVYHGQEAAQ----QRPR--DSEVEMMAQLLGIMVVASVCWLPLLVFIAQ 267
Query: 256 TIRCFTQAVAP----DSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLK 304
T+ A++P ++E L+ R +N ILDPWV+ILFR+AV +RL+
Sbjct: 268 TVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQ 320
>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
sapiens]
Length = 402
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo
sapiens]
Length = 388
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [Homo
sapiens]
Length = 418
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [Homo
sapiens]
Length = 365
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [Homo
sapiens]
Length = 374
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [Homo
sapiens]
Length = 425
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4
[Homo sapiens]
Length = 390
Score = 128 bits (321), Expect = 1e-29
Identities = 99/316 (31%), Positives = 140/316 (44%), Gaps = 33/316 (10%)
Query: 13 GSVGPATSTLMFVAGVVGNGLALGILSA----RRPARPSAFAVLVTGLAATDLLGTSFLS 68
GSV A M + G VGN LA+ ++S R R +F + + LA TDL+G +
Sbjct: 48 GSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTT 107
Query: 69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYA 128
P V V Y + G LC F MT FGL+S+ I AMAVER LA+ P+ YA
Sbjct: 108 PVVIVVYLSKQRWEHIDPSG-RLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYA 166
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRM-----------RWA 177
R R L ++ + F LP+LG+GQ+ PG+WCF+ W
Sbjct: 167 SHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNW- 225
Query: 178 QPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDH 237
G F+ A+A L L + F CN + +L R + S + G +
Sbjct: 226 --GNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQS---SAQWGRITTET 280
Query: 238 LILLALMTVVMAVCSLPLTI----RCFTQAVAPDSSSEMGD-------LLAFRFYAFNPI 286
I L + V++VC PL I F Q + L+A R + N I
Sbjct: 281 AIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQI 340
Query: 287 LDPWVFILFRKAVFQR 302
LDPWV++L RK + ++
Sbjct: 341 LDPWVYLLLRKILLRK 356
>gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens]
Length = 402
Score = 114 bits (284), Expect = 2e-25
Identities = 106/337 (31%), Positives = 147/337 (43%), Gaps = 60/337 (17%)
Query: 17 PATSTLMFVAGVVGNGLALGILSA-----RRPARPSAFAVLVTGLAATDLLGTSFLSPAV 71
PA G V N LAL +L+ RR + F + V L ATDL G V
Sbjct: 36 PALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALV 95
Query: 72 FVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLD 131
Y G A G A C M FFGL +L+ MAVERC+ ++ P L+A
Sbjct: 96 LRLYTA-----GRAPAGGA-CHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARV 149
Query: 132 GPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSL----- 186
ARLAL A+ A + LPL +G+++ PG+WCF+ + PGG +L
Sbjct: 150 SVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGL--GPPGGWRQALLAGLF 207
Query: 187 AYAGLVALLVAAIFLCNGSVTLSLCRM-YRQQ------------KRHQGSLGPRP----- 228
A GLVALL A + CN L+L R +R++ +R G+ GPR
Sbjct: 208 ASLGLVALLAALV--CNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASS 265
Query: 229 ---------------------RTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPD 267
R +V+ + L + VV +C P+ +
Sbjct: 266 ASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWS 325
Query: 268 SSSEMGDL-LAFRFYAFNPILDPWVFILFRKAVFQRL 303
S+S L LA R ++N ILDPWV+IL R+AV ++L
Sbjct: 326 STSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQL 362
>gi|4506261 prostaglandin F receptor isoform a precursor [Homo
sapiens]
Length = 359
Score = 110 bits (275), Expect = 2e-24
Identities = 80/294 (27%), Positives = 130/294 (44%), Gaps = 21/294 (7%)
Query: 20 STLMFVAGVVGNGLALGILSAR----RPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAY 75
S + G++ N LA+ IL R ++F +L +GL TD G Y
Sbjct: 33 SVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVY 92
Query: 76 ARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRC 135
A + + + LC F M F GL +L+ MA+ERC+ ++ P ++ +
Sbjct: 93 ASDKEWIRFDQSN-VLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKH 151
Query: 136 ARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSL---AYAGLV 192
++ L + F V LP+LG ++ +WCF + F L ++ GL+
Sbjct: 152 VKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLL 211
Query: 193 ALLVAAIFLCNGSVTLSLCRM-YRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVC 251
AL V+ LCN ++L R+ ++ Q+ QG ++ +I L + V +C
Sbjct: 212 ALGVS--LLCNAITGITLLRVKFKSQQHRQGR--------SHHLEMVIQLLAIMCVSCIC 261
Query: 252 SLPLTIRCFTQAVAPDSSSEMGD--LLAFRFYAFNPILDPWVFILFRKAVFQRL 303
P + + + S E + L A R +N ILDPWV+IL RKAV + L
Sbjct: 262 WSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNL 315
>gi|88758606 prostaglandin F receptor isoform b precursor [Homo
sapiens]
Length = 297
Score = 82.4 bits (202), Expect = 6e-16
Identities = 61/243 (25%), Positives = 104/243 (42%), Gaps = 19/243 (7%)
Query: 20 STLMFVAGVVGNGLALGILSAR----RPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAY 75
S + G++ N LA+ IL R ++F +L +GL TD G Y
Sbjct: 33 SVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVY 92
Query: 76 ARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRC 135
A + + + LC F M F GL +L+ MA+ERC+ ++ P ++ +
Sbjct: 93 ASDKEWIRFDQSN-VLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKH 151
Query: 136 ARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSL---AYAGLV 192
++ L + F V LP+LG ++ +WCF + F L ++ GL+
Sbjct: 152 VKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLL 211
Query: 193 ALLVAAIFLCNGSVTLSLCRM-YRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVC 251
AL V+ LCN ++L R+ ++ Q+ QG ++ +I L + V +C
Sbjct: 212 ALGVS--LLCNAITGITLLRVKFKSQQHRQGR--------SHHLEMVIQLLAIMCVSCIC 261
Query: 252 SLP 254
P
Sbjct: 262 WSP 264
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 59.3 bits (142), Expect = 6e-09
Identities = 89/348 (25%), Positives = 137/348 (39%), Gaps = 38/348 (10%)
Query: 22 LMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSL 81
L+ + G+VGN L + ++ R +A + + LA D L F+ FVA +S+
Sbjct: 56 LVCLVGLVGNALVIFVI-LRYAKMKTATNIYLLNLAVADEL---FMLSVPFVA---SSAA 108
Query: 82 LGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALP 141
L G LC A S+ L ++V+R +A+ HP A P A+L
Sbjct: 109 LRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINL 168
Query: 142 AIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALL--VAAI 199
++ L LP+ + G ++W P +A + Y L+ L V AI
Sbjct: 169 GVW-LASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAI 227
Query: 200 FLCN----GSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPL 255
LC G + R QQ+R E ++ L+L ++ VV +C +P
Sbjct: 228 GLCYLLIVGKMRAVALRAGWQQRRR----------SEKKITRLVL--MVVVVFVLCWMPF 275
Query: 256 TIRCFTQAVAPDSSSEMGDLLAFRFYA---FNPILDPWVFILFRKAVFQRLKLWVCCLCL 312
+ + + + YA NPIL ++ FR+ FQR+ CCL
Sbjct: 276 YVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRR-FFQRVLCLRCCLLE 334
Query: 313 GPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEG-QVEP 359
G A G + PL A+ A + G C PL E Q EP
Sbjct: 335 G-AGGAEEEPLDYYAT------ALKSKGGAGCMCPPLPCQQEALQPEP 375
>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
Length = 426
Score = 57.4 bits (137), Expect = 2e-08
Identities = 108/389 (27%), Positives = 151/389 (38%), Gaps = 69/389 (17%)
Query: 18 ATSTLMFVAGVVGNGL-ALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYA 76
AT L+FV G VGNGL L IL + P+ + + LA +DLL P
Sbjct: 65 ATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLF--SLAVSDLLVLLVGLPLELYEMW 122
Query: 77 RNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCA 136
N L L GG C LAS+L + A++VER +A+ HP +
Sbjct: 123 HNYPFL-LGVGG---CYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHV 178
Query: 137 RLALPAIYAFCVLFCALPLLGL-GQHQQYCPGSWCFLRMRWAQPGGAAFSL----AYAGL 191
R L A++ +L C+LP L G Q + P R P A L A +
Sbjct: 179 RRVLGAVWGLAML-CSLPNTSLHGIRQLHVP-------CRGPVPDSAVCMLVRPRALYNM 230
Query: 192 VALLVAAIFLCNGSVTLSL------CRMYR------QQKRHQGSLGPRPR---------T 230
V A +F C +S+ R+ R Q+ + +GS R R
Sbjct: 231 VVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDR 290
Query: 231 GEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFR---------FY 281
G +V +L ++ VV +C P +V S G LAF+ FY
Sbjct: 291 GRRQVTK--MLFVLVVVFGICWAPFHADRVMWSVV--SQWTDGLHLAFQHVHVISGIFFY 346
Query: 282 ---AFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSA 338
A NP+L + FR+ + L L CC L P H S LS++ +G +
Sbjct: 347 LGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRPRH--SSHSLSRMTTG-----STLC 399
Query: 339 PVGKEGSCVPLSAWGEGQVEPLPPTQQSS 367
VG GS V A +G P QQ +
Sbjct: 400 DVGSLGSWVHPLAGNDG-----PEAQQET 423
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 55.8 bits (133), Expect = 6e-08
Identities = 87/322 (27%), Positives = 137/322 (42%), Gaps = 44/322 (13%)
Query: 12 RGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAV 71
R + P L+ AG+ GN L + ++ R + + + LA D+L ++
Sbjct: 39 RAVLVPVLYLLVCAAGLGGNTLVIYVV-LRFAKMKTVTNIYILNLAVADVL---YMLGLP 94
Query: 72 FVAYARNSSLLGLARGGPALCDAFAFAMTFFGL---ASMLILFAMAVERCLALSHPYLYA 128
F+A +S GP LC MT G+ S+ L M+V+R LA+ HP A
Sbjct: 95 FLATQNAASFWPF---GPVLC---RLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSA 148
Query: 129 QLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGG--AAFSL 186
+ PR A+LA A + L +LPLL Q+ G C W +P G A +
Sbjct: 149 RWRRPRVAKLASAAAWVLS-LCMSLPLLVFADVQE---GGTC--NASWPEPVGLWGAVFI 202
Query: 187 AYAGLVALLVAAIFLCNGSVTLSLCRMYRQQK-RHQG-SLGPRPRTGEDEVDHLILLALM 244
Y ++ + +C LC + K R G +G R E +V ++L+ ++
Sbjct: 203 IYTAVLGFFAPLLVIC-------LCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVL 255
Query: 245 TVVMAVCSLP-LTIRCFTQAVA-PDSSSEMG-----DLLAFRFYAFNPILDPWVFILFRK 297
V A C LP T+ AVA P + G +L++ NP+L ++ FR+
Sbjct: 256 --VFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQ 313
Query: 298 AVFQRLKLWVCCLCLGPAHGDS 319
+ FQ+ V CL G D+
Sbjct: 314 S-FQK----VLCLRKGSGAKDA 330
>gi|4885299 G protein-coupled receptor 15 [Homo sapiens]
Length = 360
Score = 55.8 bits (133), Expect = 6e-08
Identities = 68/309 (22%), Positives = 125/309 (40%), Gaps = 41/309 (13%)
Query: 17 PATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYA 76
P T +F+ GV+GN + +G L + P + + LAA+D F+ +
Sbjct: 37 PVFYTAVFLTGVLGNLVLMGALHFK-PGSRRLIDIFIINLAASD-----FIFLVTLPLWV 90
Query: 77 RNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCA 136
+ LGL R G LC ++ ++ S+L+L M+V+R LA+ P + + CA
Sbjct: 91 DKEASLGLWRTGSFLCKGSSYMISVNMHCSVLLLTCMSVDRYLAIVWPVVSRKFRRTDCA 150
Query: 137 RLALPAIYAFCVLFCALPL-----LGLGQHQQYCPGSWCF-LRMRWAQPGGAAFSLAYAG 190
+ +I+ F LP L L + YC +++ W + +L +
Sbjct: 151 YVVCASIW-FISCLLGLPTLLSRELTLIDDKPYCAEKKATPIKLIW-----SLVALIFTF 204
Query: 191 LVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAV 250
V LL +I C + LC Y+Q +H L + ++ ++ V
Sbjct: 205 FVPLL--SIVTCYCCIARKLCAHYQQSGKHNKKL----------KKSIKIIFIVVAAFLV 252
Query: 251 CSLPLTIRCFTQAVA--------PDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQR 302
LP F V+ P + ++G ++ N ++P+++ +F + +
Sbjct: 253 SWLPFNTFKFLAIVSGLRQEHYLPSAILQLGMEVSGPLAFANSCVNPFIYYIFDSYIRRA 312
Query: 303 LKLWVCCLC 311
+ V CLC
Sbjct: 313 I---VHCLC 318
>gi|9506747 G protein-coupled receptor 27 [Homo sapiens]
Length = 375
Score = 55.5 bits (132), Expect = 8e-08
Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 9/185 (4%)
Query: 18 ATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYAR 77
AT +L+ + GN L +L R + A L+ L D L PAV +A R
Sbjct: 23 ATLSLLLCVSLAGNVL-FALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARR 81
Query: 78 NSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQ-LDGPRCA 136
++ G A G C AF F + +L + V R LA++H YA+ L G CA
Sbjct: 82 AAAAAG-APPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCA 140
Query: 137 RLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLV 196
+ + A +A + P+L G + P C L R P GA +L + L+A++V
Sbjct: 141 AMLVCAAWALALAAAFPPVLDGGGDDEDAP---CALEQR---PDGAPGALGFLLLLAVVV 194
Query: 197 AAIFL 201
A L
Sbjct: 195 GATHL 199
>gi|4503907 galanin receptor 3 [Homo sapiens]
Length = 368
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/208 (28%), Positives = 82/208 (39%), Gaps = 26/208 (12%)
Query: 13 GSVG----PATSTLMFVAGVVGNGLALGILSARRPAR----PSAFAVLVTGLAATDLLGT 64
GSVG P L+F+ G VGNGL L +L P+ S + + LA DL
Sbjct: 13 GSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFI 72
Query: 65 SFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHP 124
P Y ++ L G +C A + AS L A++V+R LA+ HP
Sbjct: 73 LCCVPFQATIYTLDAWLFGAL-----VCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHP 127
Query: 125 YLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQ----QYCPGSWCFLRMRWAQPG 180
L PR AR A+ ++ LF A L G + + C +W R R
Sbjct: 128 LRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVA 187
Query: 181 G---------AAFSLAYAGLVALLVAAI 199
A SLAY + L AA+
Sbjct: 188 TFAAGYLLPVAVVSLAYGRTLRFLWAAV 215
>gi|9789897 leukotriene B4 receptor 2 [Homo sapiens]
Length = 389
Score = 54.3 bits (129), Expect = 2e-07
Identities = 47/143 (32%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 14 SVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAV-LVTGLAATDLLGTSFLSPAVF 72
+ G A L + G+ GNG + L+ RPAR A LV LA D G L +F
Sbjct: 52 ATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALAD--GAVLLLTPLF 109
Query: 73 VAY-ARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLD 131
VA+ R + LG A C A + AS+L+ ++++RCLA++ P+L +L
Sbjct: 110 VAFLTRQAWPLGQAG-----CKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLR 164
Query: 132 GPRCARLALPAIYAFCVLFCALP 154
P AR L A++ L A+P
Sbjct: 165 SPALARRLLLAVW-LAALLLAVP 186
>gi|89353783 coagulation factor II (thrombin) receptor-like 3
precursor [Homo sapiens]
Length = 385
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/157 (34%), Positives = 74/157 (47%), Gaps = 12/157 (7%)
Query: 1 MADSCRNLT--YVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAA 58
+ DS R L +V + PA L+ V G+ NGLAL +L+ + P PS +L+ LAA
Sbjct: 63 LPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPS--TMLLMNLAA 120
Query: 59 TDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERC 118
DLL L P +AY G A C A+ S+L+L A++++R
Sbjct: 121 ADLLLALALPPR--IAYHLRGQRWPF---GEAACRLATAALYGHMYGSVLLLAAVSLDRY 175
Query: 119 LALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPL 155
LAL HP L G RLAL A ++ AL L
Sbjct: 176 LALVHPLRARALRG---RRLALGLCMAAWLMAAALAL 209
>gi|5730019 peropsin [Homo sapiens]
Length = 337
Score = 53.9 bits (128), Expect = 2e-07
Identities = 67/296 (22%), Positives = 127/296 (42%), Gaps = 25/296 (8%)
Query: 20 STLMFVAG---VVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYA 76
+T + +AG ++ N + LGI + R A+++ LA TD+ G S + + A
Sbjct: 29 ATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIIN-LAVTDI-GVSSIGYPMSAA-- 84
Query: 77 RNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCA 136
S L G + G A C +A FFG+AS+ +L +AV+R L + P + ++
Sbjct: 85 --SDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYI 142
Query: 137 RLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALL- 195
L L A + + + +P++G + G+ C + R ++++ + ++
Sbjct: 143 GLILGA-WINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVP 201
Query: 196 VAAIFLCNGSVTLSLCRMYRQQKRHQGS--LGPRPRTGEDEVDHLILLALMTVVMAVCSL 253
+ +F C VTLS+ K H S R D++D + +M + V
Sbjct: 202 LTVMFYCYYHVTLSI-------KHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWS 254
Query: 254 PLTIRCFTQAVA-PDSSSEMGDLLAFRFYAFNPILDPWVFIL----FRKAVFQRLK 304
P +I C + P ++A F + +P ++++ FR+A+ K
Sbjct: 255 PYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFK 310
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 52.0 bits (123), Expect = 9e-07
Identities = 66/290 (22%), Positives = 115/290 (39%), Gaps = 19/290 (6%)
Query: 22 LMFVAGVVGNGLALGILSARRPARP-SAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSS 80
L+F GV+GN L + +L+ +P +P S + + L+ DL F P YA +
Sbjct: 42 LIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTW 101
Query: 81 LLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLAL 140
+L G +C + T L S+ L AM+V+R +A+ H + L R A L +
Sbjct: 102 VL-----GAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGV 156
Query: 141 PAIYAFCVLFCALPLLGLG------QHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVAL 194
I+A + + G +Q +C W R + A + + L+ L
Sbjct: 157 GCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAY---VVCTFVFGYLLPL 213
Query: 195 LVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLP 254
L+ I C V L + + + S + +T + + +++ + + + L
Sbjct: 214 LL--ICFCYAKVLNHLHKKLKNMSKK--SEASKKKTAQTVLVVVVVFGISWLPHHIIHLW 269
Query: 255 LTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLK 304
F A LA+ + NPI+ ++ FRKA Q K
Sbjct: 270 AEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFK 319
>gi|55953085 G protein-coupled receptor 120 [Homo sapiens]
Length = 377
Score = 52.0 bits (123), Expect = 9e-07
Identities = 55/208 (26%), Positives = 87/208 (41%), Gaps = 24/208 (11%)
Query: 11 VRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPA 70
V +V L+F ++GN AL +++ RR R A A LV L DLL S + P
Sbjct: 38 VLAAVETTVLVLIFAVSLLGNVCALVLVARRR--RRGATACLVLNLFCADLLFISAI-PL 94
Query: 71 VFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQL 130
V + LLG P C + MT G ++L L A+++ER + + H +
Sbjct: 95 VLAVRWTEAWLLG-----PVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRG 149
Query: 131 DGPRCARLALPAIYAF--------CVLFCALP--LLGLGQHQQYCPGSWCFLRMRWAQPG 180
G R + L I+ + CV F +P L G Q C W + PG
Sbjct: 150 PGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTI------PG 203
Query: 181 GAAFSLAYAGLVALLVAAIFLCNGSVTL 208
++ +++ L L+ + + + S L
Sbjct: 204 EISWDVSFVTLNFLVPGLVIVISYSKIL 231
>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
Length = 371
Score = 51.6 bits (122), Expect = 1e-06
Identities = 83/339 (24%), Positives = 127/339 (37%), Gaps = 43/339 (12%)
Query: 18 ATSTLMFVAGVVGNGLALGILSAR-RPARPSAFAVLVTGLAATDLLGTSF--LSPAVFVA 74
A +++FVA + NGL L L+ R R + V + L DL F L + A
Sbjct: 42 ALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKA 101
Query: 75 YARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYL-YAQLDGP 133
R RG ALC A + AS ++ AM ++R A+ P L Y G
Sbjct: 102 TDR-------FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGA 154
Query: 134 RCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGS-----W-CFLRMRWAQPGGAAFSLA 187
R L A +AF +L +LP L + + GS W CF A+P G +
Sbjct: 155 HWNRPVLVA-WAFSLLL-SLPQLFIFAQRNVEGGSGVTDCWACF-----AEPWGRRTYVT 207
Query: 188 YAGLVALLVAAIFLCNGSVTL------------SLCRMYRQQKRHQGSLGPRPRTGEDEV 235
+ L+ + + + V + S R++ R GS G
Sbjct: 208 WIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVA 267
Query: 236 DHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYA-FNPILDPWVFIL 294
+ + ++ VV +C P + A P++ E + A N +PW++
Sbjct: 268 KTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYAS 327
Query: 295 FRKAVFQRLKLWVCCL------CLGPAHGDSQTPLSQLA 327
F +V L+ +CC LGP T S LA
Sbjct: 328 FSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLA 366
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,697,503
Number of Sequences: 37866
Number of extensions: 727059
Number of successful extensions: 3319
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 3076
Number of HSP's gapped (non-prelim): 402
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.