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Search of human proteins with 4506259
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo
sapiens]
(488 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens] 959 0.0
gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo s... 183 3e-46
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom... 173 3e-43
gi|28466969 prostaglandin D2 receptor [Homo sapiens] 160 2e-39
gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [H... 137 2e-32
gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H... 130 3e-30
gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 130 3e-30
gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 130 3e-30
gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [H... 130 3e-30
gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4 [... 130 3e-30
gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens] 130 3e-30
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 130 4e-30
gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [H... 130 4e-30
gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [H... 130 4e-30
gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [H... 130 4e-30
gi|4507381 thromboxane A2 receptor [Homo sapiens] 115 9e-26
gi|4506261 prostaglandin F receptor isoform a precursor [Homo sa... 90 4e-18
gi|113420725 PREDICTED: similar to hCG2039164 [Homo sapiens] 86 6e-17
gi|169184233 PREDICTED: similar to hCG2039164 [Homo sapiens] 85 2e-16
gi|169178703 PREDICTED: similar to hCG2039164 [Homo sapiens] 84 2e-16
gi|239752566 PREDICTED: similar to hCG2039164 [Homo sapiens] 84 2e-16
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 79 1e-14
gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo sa... 73 5e-13
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 70 3e-12
gi|16876435 G protein-coupled receptor 101 [Homo sapiens] 68 2e-11
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 67 3e-11
gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens] 67 4e-11
gi|88758606 prostaglandin F receptor isoform b precursor [Homo s... 66 8e-11
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 65 1e-10
gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens] 64 2e-10
>gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens]
Length = 488
Score = 959 bits (2478), Expect = 0.0
Identities = 488/488 (100%), Positives = 488/488 (100%)
Query: 1 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG 60
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
Sbjct: 1 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG 60
Query: 61 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA 120
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
Sbjct: 61 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA 120
Query: 121 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA 180
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
Sbjct: 121 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA 180
Query: 181 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG 240
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
Sbjct: 181 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG 240
Query: 241 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP 300
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
Sbjct: 241 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP 300
Query: 301 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG 360
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
Sbjct: 301 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG 360
Query: 361 QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG 420
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
Sbjct: 361 QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG 420
Query: 421 MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET 480
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
Sbjct: 421 MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET 480
Query: 481 LNLSEKCI 488
LNLSEKCI
Sbjct: 481 LNLSEKCI 488
>gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
sapiens]
Length = 386
Score = 183 bits (465), Expect = 3e-46
Identities = 119/327 (36%), Positives = 165/327 (50%), Gaps = 43/327 (13%)
Query: 26 VMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMK--- 82
+MF+ GVVGN +A+ +L +R+ + + F LV GLA TDLLGT +SP Y +
Sbjct: 22 LMFVAGVVGNGLALGIL-SARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSS 80
Query: 83 --GQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTL 140
G GG LC+ F + FF L+ + I+ AM+VER LA++H Y Y+ R A L L
Sbjct: 81 LLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLAL 140
Query: 141 FAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATV 200
A+YA VLFCALP +GLG + P +WCF+ AA+S YAG + L+ A
Sbjct: 141 PAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIF 200
Query: 201 LCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSF 260
LCN V +L RM+RQ R H + PR +
Sbjct: 201 LCNGSVTLSLCRMYRQQKR---------------------HQGSLGPRPRTGE------- 232
Query: 261 RRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASV 320
E+ +ILL ++V+ +CS+PL +R F Q P E+ DL A R +
Sbjct: 233 -----DEVDHLILLALMTVVMAVCSLPLTIRCF-TQAVAPDSSSEMG---DLLAFRFYAF 283
Query: 321 NPILDPWIYILLRKTVLSKAIEKIKCL 347
NPILDPW++IL RK V + + CL
Sbjct: 284 NPILDPWVFILFRKAVFQRLKLWVCCL 310
>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
sapiens]
Length = 358
Score = 173 bits (439), Expect = 3e-43
Identities = 121/362 (33%), Positives = 180/362 (49%), Gaps = 49/362 (13%)
Query: 23 IPAVMFIFGVVGNLVAIVVL---------CKSRKEQKETTFYTLVCGLAVTDLLGTLLVS 73
I +VMF GV+GNL+A+ +L C + + + F+ LV L TDLLGT L+S
Sbjct: 27 ISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLIS 86
Query: 74 PVTIATYMKGQW-----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYS 128
PV +A+Y + Q P + C Y F + FFSL+ + ++ AM++ERYL+I H YFY
Sbjct: 87 PVVLASYARNQTLVALAPESRA-CTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQ 145
Query: 129 HYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMY 188
V + L +YA ++LFC+LP + G P TWCFI AY +Y
Sbjct: 146 RRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIR-----HGRTAYLQLY 200
Query: 189 AGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPAL 248
A LI++ + CN V L+RMHR+ RR+ G + + RG P A
Sbjct: 201 ATLLLLLIVSVLACNFSVILNLIRMHRR-SRRSRCG--------PSLGSGRGGPGA---- 247
Query: 249 PRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSK 308
RRR R E +ILL ++ +CS+P + ++N + S +E
Sbjct: 248 -------RRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMN---ETSSRKE--- 294
Query: 309 NPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQR 368
DLQA+R S+N I+DPW++ +LR VL + + + C CRI ++ + CS
Sbjct: 295 KWDLQALRFLSINSIIDPWVFAILRPPVL-RLMRSVLC--CRISLRTQDATQTSCSTQSD 351
Query: 369 TS 370
S
Sbjct: 352 AS 353
>gi|28466969 prostaglandin D2 receptor [Homo sapiens]
Length = 359
Score = 160 bits (406), Expect = 2e-39
Identities = 120/390 (30%), Positives = 182/390 (46%), Gaps = 48/390 (12%)
Query: 1 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKS------RKEQKE--T 52
M +P + S ++ NS V + V+F G++GNL+A+ +L +S R+ + +
Sbjct: 1 MKSPFYRCQNTTSVEKGNSAV-MGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPS 59
Query: 53 TFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQW-----PG-GQPLCEYSTFILLFFSLSG 106
FY LVCGL VTDLLG L+SPV +A Y + + P LC+ F + FF LS
Sbjct: 60 VFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSS 119
Query: 107 LSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYP 166
+ AM++E +L++ H +FY ++ RL L V A ++ FCALP MG G P
Sbjct: 120 TLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCP 179
Query: 167 DTWCFIDWT--TNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLG 224
TWCFI + YS +Y+ + L+LATVLCN+ L MHR+ R
Sbjct: 180 GTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSC 239
Query: 225 TEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLIC 284
T A + G A+ L E+ ++LL +++ +C
Sbjct: 240 TRD-----CAEPRADGREASPQPL-----------------EELDHLLLLALMTVLFTMC 277
Query: 285 SIPLVVRVFVNQLYQPSLEREVSKN-PDLQAIRIASVNPILDPWIYILLRKTVLSKAIEK 343
S+P++ R + + S+ DL+A+R SV I+DPWI+I+ R V K
Sbjct: 278 SLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHK 337
Query: 344 IKCLFCRIGGSRRERSGQHCSDSQRTSSAM 373
I R R CS+S S++
Sbjct: 338 IFI--------RPLRYRSRCSNSTNMESSL 359
>gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [Homo
sapiens]
Length = 418
Score = 137 bits (346), Expect = 2e-32
Identities = 113/375 (30%), Positives = 172/375 (45%), Gaps = 65/375 (17%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIK-----CLFCRIG 352
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K + K L C +
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQLICSLQ 374
Query: 353 GSRRERSGQHCSDSQ 367
S+ +R+ HC Q
Sbjct: 375 NSQIQRATAHCGQVQ 389
>gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo
sapiens]
Length = 388
Score = 130 bits (327), Expect = 3e-30
Identities = 107/357 (29%), Positives = 164/357 (45%), Gaps = 68/357 (19%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGS 354
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K FC++ +
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK--------FCQVANA 363
>gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 130 bits (327), Expect = 3e-30
Identities = 108/354 (30%), Positives = 163/354 (46%), Gaps = 68/354 (19%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRI 351
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K FC+I
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK--------FCQI 360
>gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 130 bits (327), Expect = 3e-30
Identities = 108/354 (30%), Positives = 163/354 (46%), Gaps = 68/354 (19%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRI 351
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K FC+I
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK--------FCQI 360
>gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [Homo
sapiens]
Length = 393
Score = 130 bits (327), Expect = 3e-30
Identities = 105/347 (30%), Positives = 162/347 (46%), Gaps = 60/347 (17%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKI 344
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K +++
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEM 361
>gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4
[Homo sapiens]
Length = 390
Score = 130 bits (327), Expect = 3e-30
Identities = 108/354 (30%), Positives = 163/354 (46%), Gaps = 68/354 (19%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRI 351
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K FC+I
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK--------FCQI 360
>gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens]
Length = 402
Score = 130 bits (327), Expect = 3e-30
Identities = 107/355 (30%), Positives = 165/355 (46%), Gaps = 25/355 (7%)
Query: 2 STPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKS----RKEQKETTFYTL 57
+ P V +++++ P + +P G V NL+A+ +L ++ R+ + TF
Sbjct: 19 AAPWVPNTSAVPPS--GASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLF 76
Query: 58 VCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVER 117
V L TDL G ++ + + Y G+ P G C + ++FF L L + C M+VER
Sbjct: 77 VASLLATDLAGHVIPGALVLRLYTAGRAPAGGA-CHFLGGCMVFFGLCPLLLGCGMAVER 135
Query: 118 YLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID-WTT 176
+ + ++ V A L L AV A + LP +G LQYP TWCFI
Sbjct: 136 CVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPP 195
Query: 177 NVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMH-RQFMRR--TSLGTEQH----- 228
A + ++A +LA ++CN L ALLR R+ RR + G +
Sbjct: 196 GGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGA 255
Query: 229 HAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPL 288
H +AS +S A++ R S RR +++MV L+ +V IC P+
Sbjct: 256 HGPRSASASSASSIASASTF--FGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPM 313
Query: 289 VVRV--FVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAI 341
+V V V SL+R P A+R+AS N ILDPW+YILLR+ VL + +
Sbjct: 314 LVLVALAVGGWSSTSLQR-----PLFLAVRLASWNQILDPWVYILLRQAVLRQLL 363
>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
sapiens]
Length = 402
Score = 130 bits (326), Expect = 4e-30
Identities = 105/342 (30%), Positives = 159/342 (46%), Gaps = 60/342 (17%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSK 339
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK 356
>gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [Homo
sapiens]
Length = 365
Score = 130 bits (326), Expect = 4e-30
Identities = 105/342 (30%), Positives = 159/342 (46%), Gaps = 60/342 (17%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSK 339
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK 356
>gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [Homo
sapiens]
Length = 374
Score = 130 bits (326), Expect = 4e-30
Identities = 105/342 (30%), Positives = 159/342 (46%), Gaps = 60/342 (17%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSK 339
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK 356
>gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [Homo
sapiens]
Length = 425
Score = 130 bits (326), Expect = 4e-30
Identities = 105/342 (30%), Positives = 159/342 (46%), Gaps = 60/342 (17%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKS--RKEQKETTFYTLVCG-LAVTDLLGTLLVSPVTI 77
V P M + G VGN +A++++ +S R+E K + L G LA+TDL+G LL +PV I
Sbjct: 52 VAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVI 111
Query: 78 ATYM-KGQW----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVD 132
Y+ K +W P G+ LC + + F LS L I AM+VER LAI ++Y+ ++
Sbjct: 112 VVYLSKQRWEHIDPSGR-LCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMK 170
Query: 133 KRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID----WTTNVTAHAAYSYMY 188
R L V+ + + F LP +G+G +Q+P TWCFI ++H + +
Sbjct: 171 TRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFF 230
Query: 189 AGFSSFL----ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAA 244
A +FL + T CN+ AL+ R A A+ S A G
Sbjct: 231 ASAFAFLGLLALTVTFSCNLATIKALVSRCRA------------KATASQSSAQWGRITT 278
Query: 245 SPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL-- 302
A I L+ V+ +C PL++ + Q S+
Sbjct: 279 ETA------------------------IQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEH 314
Query: 303 -----EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSK 339
E++ N L A+R+AS+N ILDPW+Y+LLRK +L K
Sbjct: 315 CKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRK 356
>gi|4507381 thromboxane A2 receptor [Homo sapiens]
Length = 343
Score = 115 bits (288), Expect = 9e-26
Identities = 89/345 (25%), Positives = 152/345 (44%), Gaps = 54/345 (15%)
Query: 8 SSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKET--TFYTLVCGLAVTD 65
++ +L RL + A + G+ NL+A+ VL +R+ T +F T +CGL +TD
Sbjct: 15 TNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTD 74
Query: 66 LLGTLLVSPVTIATYMK-GQWPGGQP---LCEYSTFILLFFSLSGLSIICAMSVERYLAI 121
LG L+ + ++ + +W P LC + +++FF LS L + AM+ ERYL I
Sbjct: 75 FLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGI 134
Query: 122 NHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAH 181
+ +R A T+ V+A+ + LP +G+G +QYP +WCF+ +
Sbjct: 135 TRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAE-SGD 193
Query: 182 AAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGH 241
A+ +++ + + L N + L + +H AA
Sbjct: 194 VAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV--------------YHGQEAAQ------ 233
Query: 242 PAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP- 300
+R +E++M+ L+ +V +C +PL+V + L P
Sbjct: 234 -------------------QRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPP 274
Query: 301 ------SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSK 339
L R K L +R+A+ N ILDPW+YIL R+ VL +
Sbjct: 275 AMSPAGQLSRTTEKEL-LIYLRVATWNQILDPWVYILFRRAVLRR 318
>gi|4506261 prostaglandin F receptor isoform a precursor [Homo
sapiens]
Length = 359
Score = 90.1 bits (222), Expect = 4e-18
Identities = 89/350 (25%), Positives = 144/350 (41%), Gaps = 73/350 (20%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKSR---KEQKETTFYTLVCGLAVTDLLGTLLVSPVTI 77
V + G++ N +AI +L K+ +++ + +F L GL +TD G L+ + +
Sbjct: 30 VFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAV 89
Query: 78 ATYMKGQ----WPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYS----- 128
Y + + LC ++F L L + M++ER + + F+S
Sbjct: 90 FVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITS 149
Query: 129 HYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFI------DWTTNVTAHA 182
+V L+G+ LFAV+ + LP +G ++Q TWCF DW
Sbjct: 150 KHVKMMLSGVCLFAVFIA-----LLPILGHRDYKIQASRTWCFYNTEDIKDWEDRF---- 200
Query: 183 AYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHP 242
Y +++ + ++LCN + LLR+ ++QH R H
Sbjct: 201 -YLLLFSFLGLLALGVSLLCNAITGITLLRV--------KFKSQQHR-------QGRSH- 243
Query: 243 AASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIP-LVVRVFVNQLYQPS 301
++MVI L+A V IC P LV + S
Sbjct: 244 ------------------------HLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHS 279
Query: 302 LEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRI 351
LE + L A+R+A+ N ILDPW+YILLRK VL K + K+ C +
Sbjct: 280 LE---TCETTLFALRMATWNQILDPWVYILLRKAVL-KNLYKLASQCCGV 325
>gi|113420725 PREDICTED: similar to hCG2039164 [Homo sapiens]
Length = 239
Score = 86.3 bits (212), Expect = 6e-17
Identities = 48/55 (87%), Positives = 48/55 (87%), Gaps = 1/55 (1%)
Query: 29 IFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKG 83
IFGVVGNLVAIVVLCKSRKEQKETTFYT V LA TDLL TLLVS VTIA YMKG
Sbjct: 185 IFGVVGNLVAIVVLCKSRKEQKETTFYT-VMRLAATDLLFTLLVSQVTIAMYMKG 238
>gi|169184233 PREDICTED: similar to hCG2039164 [Homo sapiens]
Length = 239
Score = 84.7 bits (208), Expect = 2e-16
Identities = 47/55 (85%), Positives = 47/55 (85%), Gaps = 1/55 (1%)
Query: 29 IFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKG 83
IFGVVGNLVAIVVLCKSRKEQKETTFYT V L TDLL TLLVS VTIA YMKG
Sbjct: 185 IFGVVGNLVAIVVLCKSRKEQKETTFYT-VMRLVATDLLFTLLVSQVTIAMYMKG 238
>gi|169178703 PREDICTED: similar to hCG2039164 [Homo sapiens]
Length = 239
Score = 84.3 bits (207), Expect = 2e-16
Identities = 47/55 (85%), Positives = 47/55 (85%), Gaps = 1/55 (1%)
Query: 29 IFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKG 83
IFGVVGNLVAIVVLCKS KEQKETTFYT V LA TDLL TLLVS VTIA YMKG
Sbjct: 185 IFGVVGNLVAIVVLCKSHKEQKETTFYT-VMWLAATDLLFTLLVSQVTIAMYMKG 238
>gi|239752566 PREDICTED: similar to hCG2039164 [Homo sapiens]
Length = 239
Score = 84.3 bits (207), Expect = 2e-16
Identities = 47/55 (85%), Positives = 47/55 (85%), Gaps = 1/55 (1%)
Query: 29 IFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKG 83
IFGVVGNLVAIVVLCKS KEQKETTFYT V LA TDLL TLLVS VTIA YMKG
Sbjct: 185 IFGVVGNLVAIVVLCKSHKEQKETTFYT-VMRLAATDLLFTLLVSQVTIAMYMKG 238
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 78.6 bits (192), Expect = 1e-14
Identities = 82/372 (22%), Positives = 147/372 (39%), Gaps = 40/372 (10%)
Query: 4 PGVNSSASLSPD----RLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVC 59
P SS S P R S + +F +VGN++ I+ + +R + T ++ +
Sbjct: 28 PNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYF--IV 85
Query: 60 GLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYL 119
LA+ DLL + V P + A + G W G+ C+ + + + + +CA+S++RY+
Sbjct: 86 NLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYI 145
Query: 120 AINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVT 179
+ ++ Y V +R A L L +V+ + + P +G D C + T
Sbjct: 146 GVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLG-WKEPAPNDDKECGV---TEEP 201
Query: 180 AHAAYSYMYAGFSSFLILATVLCNV----------LVCGALLRMHRQFMRRTSLGTEQHH 229
+A +S + + + ++ + C V L G + M + ++ H
Sbjct: 202 FYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFH 261
Query: 230 AAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLV 289
+S ++GH S +L F R + + G + M IL C +P
Sbjct: 262 EDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFIL----------CWLPFF 311
Query: 290 VRVFVNQLYQPSLEREVSKNPDL---QAIRIASVNPILDPWIYILLRKTVLSKAIEKIKC 346
+ + + L+ K PD + N L+P IY K +A +I
Sbjct: 312 IALPLGSLF------STLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKE-FKRAFVRILG 364
Query: 347 LFCRIGGSRRER 358
CR G RR R
Sbjct: 365 CQCRGRGRRRRR 376
>gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo
sapiens]
Length = 471
Score = 73.2 bits (178), Expect = 5e-13
Identities = 79/344 (22%), Positives = 147/344 (42%), Gaps = 32/344 (9%)
Query: 18 NSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTI 77
N + AV+ I + GN++ I+ + +K Q T ++ + LA+ D+L LV PV++
Sbjct: 75 NWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLM--SLAIADMLLGFLVMPVSM 132
Query: 78 ATYMKG-QWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLA 136
T + G +WP LC ++ + FS + + +CA+S++RY+AI + +S + + A
Sbjct: 133 LTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKA 192
Query: 137 GLTLFAVYASNV-LFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFL 195
L + AV+ +V + +P GL + + C + V + F SF
Sbjct: 193 FLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFV--------LIGSFVSFF 244
Query: 196 ILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGH-PAASPALPRL--- 251
I T++ + + LGT A +AS P +S + +L
Sbjct: 245 IPLTIMVITYFLTIKSLQKEATLCVSDLGTR-------AKLASFSFLPQSSLSSEKLFQR 297
Query: 252 ------SDFRRRRSFRRIAGAEIQMVILLIATSL-VVLICSIPLVVRVFVNQLYQPSLER 304
+ RR+ + I+ + +L I L VV+ C P + + + + S
Sbjct: 298 SIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWC--PFFITNIMAVICKESCNE 355
Query: 305 EVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLF 348
+V + I ++ ++P +Y L KT S I+C +
Sbjct: 356 DVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQY 399
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 70.5 bits (171), Expect = 3e-12
Identities = 86/377 (22%), Positives = 152/377 (40%), Gaps = 39/377 (10%)
Query: 22 TIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYM 81
T+ ++ + G++GNL I C+SR + + + LAV+D L + +PV + +
Sbjct: 75 TVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMF--IINLAVSDFLMSFTQAPVFFTSSL 132
Query: 82 KGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLF 141
QW G+ CE+ F F +S + + A++++RYL I KR A L
Sbjct: 133 YKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLL 192
Query: 142 AVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFL-ILATV 200
V+ + + P G + + T C D+ + A AY+ + F FL +L +
Sbjct: 193 GVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIII 252
Query: 201 LCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSF 260
C + + A+ R A A +G+ S ++R+R
Sbjct: 253 YCYIFIFRAIRETGR---------------ALQTFGACKGNGE--------SLWQRQRLQ 289
Query: 261 RRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASV 320
A+I ++++L L VL + V + Y L +S P + IA
Sbjct: 290 SECKMAKIMLLVIL----LFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAV----IAKA 341
Query: 321 NPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSF 380
+ I +P IY + + + CL +G SRR S + S S ++ H+ +
Sbjct: 342 SAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRR-HSRPYPSYRSTHRSTLTSHTSNL 400
Query: 381 ----ISRELKEISSTSQ 393
I R + + S S+
Sbjct: 401 SWISIRRRQESLGSESE 417
>gi|16876435 G protein-coupled receptor 101 [Homo sapiens]
Length = 508
Score = 68.2 bits (165), Expect = 2e-11
Identities = 53/196 (27%), Positives = 84/196 (42%), Gaps = 11/196 (5%)
Query: 22 TIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYM 81
T+ + VGN+V +VL RK Q + L VTDLL LV+P +AT +
Sbjct: 36 TVLVIFLAASFVGNIVLALVL--QRKPQLLQVTNRFIFNLLVTDLLQISLVAPWVVATSV 93
Query: 82 KGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLF 141
WP C + F+ + ++ I +SV+RYL+I H Y + +R L L+
Sbjct: 94 PLFWPLNSHFCTALVSLTHLFAFASVNTIVVVSVDRYLSIIHPLSYPSKMTQRRGYLLLY 153
Query: 142 AVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVL 201
+ +L P G G + + C + W A+ SY SF+++ ++
Sbjct: 154 GTWIVAILQSTPPLYGWGQAAFDERNALCSMIW------GASPSYTILSVVSFIVIPLIV 207
Query: 202 ---CNVLVCGALLRMH 214
C +V A R H
Sbjct: 208 MIACYSVVFCAARRQH 223
>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
Length = 529
Score = 67.4 bits (163), Expect = 3e-11
Identities = 89/380 (23%), Positives = 159/380 (41%), Gaps = 33/380 (8%)
Query: 26 VMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQW 85
V+ IF +GNLV +V L K K T V L +++ L ++LV P + + ++ +W
Sbjct: 36 VITIFVCLGNLVIVVTLYK--KSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREW 93
Query: 86 PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYA 145
G C +S + L S + + + ++++RY A+ + Y + A + L ++
Sbjct: 94 IFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWL 153
Query: 146 SNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVL 205
+++ C P G S C W + A+ ++ FL++ L
Sbjct: 154 HSLIGCLPPLFGWSSVEFDEFKWMCVAAWHRE-PGYTAFWQIWCALFPFLVM-------L 205
Query: 206 VC-GALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIA 264
VC G + R+ R R+ GT A + ++ S RR +F+ +
Sbjct: 206 VCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTS-----SSGSRRNAFQGVV 260
Query: 265 GAEIQMVILLIATSLVVL----ICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASV 320
+ Q L+ T LVVL + P +V + L+ S VS + + A ++
Sbjct: 261 YSANQCKALI--TILVVLGAFMVTWGPYMVVIASEALWGKS---SVSPSLETWATWLSFA 315
Query: 321 NPILDPWIYILLRKTVLSKAIEKIKCL---FCRIGGSRRERSGQHCSDSQR-TSSAMSGH 376
+ + P IY L KTV + + C + R +R+R+ + S S R T +S H
Sbjct: 316 SAVCHPLIYGLWNKTVRKELLG--MCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPH 373
Query: 377 SRSFIS--RELKEISSTSQT 394
+ ++ + L SST T
Sbjct: 374 LTALMAGGQPLGHSSSTGDT 393
>gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens]
Length = 360
Score = 67.0 bits (162), Expect = 4e-11
Identities = 47/155 (30%), Positives = 78/155 (50%), Gaps = 5/155 (3%)
Query: 25 AVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQ 84
+++F+FG++GN V ++VL K ++ + T Y L LA++DLL + S Y Q
Sbjct: 47 SLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLL--NLAISDLL--FVFSLPFWGYYAADQ 102
Query: 85 WPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVY 144
W G LC+ +++ L SG+ + MS++RYLAI HA F +T A +
Sbjct: 103 WVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATW 162
Query: 145 ASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVT 179
S +F +LP + + T+C ++ N T
Sbjct: 163 -SVAVFASLPGFLFSTCYTERNHTYCKTKYSLNST 196
>gi|88758606 prostaglandin F receptor isoform b precursor [Homo
sapiens]
Length = 297
Score = 65.9 bits (159), Expect = 8e-11
Identities = 53/220 (24%), Positives = 94/220 (42%), Gaps = 34/220 (15%)
Query: 21 VTIPAVMFIFGVVGNLVAIVVLCKSR---KEQKETTFYTLVCGLAVTDLLGTLLVSPVTI 77
V + G++ N +AI +L K+ +++ + +F L GL +TD G L+ + +
Sbjct: 30 VFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAV 89
Query: 78 ATYMKGQ----WPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYS----- 128
Y + + LC ++F L L + M++ER + + F+S
Sbjct: 90 FVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITS 149
Query: 129 HYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFI------DWTTNVTAHA 182
+V L+G+ LFAV+ + LP +G ++Q TWCF DW
Sbjct: 150 KHVKMMLSGVCLFAVFIA-----LLPILGHRDYKIQASRTWCFYNTEDIKDWEDRF---- 200
Query: 183 AYSYMYAGFSSFLILATVLCNVLVCGALLRM------HRQ 216
Y +++ + ++LCN + LLR+ HRQ
Sbjct: 201 -YLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQ 239
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 65.1 bits (157), Expect = 1e-10
Identities = 34/105 (32%), Positives = 63/105 (60%), Gaps = 4/105 (3%)
Query: 25 AVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKG- 83
+++FI G+VGNL+A+VV+ ++RK+ TT Y+ L ++D+L T + P IA Y G
Sbjct: 39 SLVFIIGLVGNLLALVVIVQNRKKINSTTLYS--TNLVISDILFTTAL-PTRIAYYAMGF 95
Query: 84 QWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYS 128
W G LC + + + +G++ + +S++R++A+ H Y+
Sbjct: 96 DWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYN 140
>gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
Length = 462
Score = 64.3 bits (155), Expect = 2e-10
Identities = 67/259 (25%), Positives = 110/259 (42%), Gaps = 25/259 (9%)
Query: 27 MFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWP 86
+ +F VVGN++ ++ + SR + + + LA D+L LV P ++A + W
Sbjct: 61 LIVFTVVGNVLVVIAVLTSRALRAPQNLFLV--SLASADILVATLVMPFSLANELMAYWY 118
Query: 87 GGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYAS 146
GQ C + + F S + +CA+S++RY ++ A Y+ R T+ AV+
Sbjct: 119 FGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLI 178
Query: 147 NVLFCALPNMGLGSSRLQYPDTWCFIDWTTN-VTAHAAYSYMYAGFSSFLILATVLCNVL 205
+ + P + L + PD + N T + S + + F+ LI+ V +
Sbjct: 179 SAVISFPPLVSL----YRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIY 234
Query: 206 VCGALLRMHRQFMRRTSLG------TEQHHAAAAASVASRGHPAASPA------LPRLSD 253
A LR +R +G T ++ AAA GH A PA ++
Sbjct: 235 RV-AKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAE 293
Query: 254 FRRRRSF-----RRIAGAE 267
RRRR RR AGAE
Sbjct: 294 RRRRRGALRRGGRRRAGAE 312
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,503,590
Number of Sequences: 37866
Number of extensions: 728034
Number of successful extensions: 3411
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 231
Number of HSP's that attempted gapping in prelim test: 2902
Number of HSP's gapped (non-prelim): 588
length of query: 488
length of database: 18,247,518
effective HSP length: 106
effective length of query: 382
effective length of database: 14,233,722
effective search space: 5437281804
effective search space used: 5437281804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.