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Search of human proteins with 4505881
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505881 plasminogen [Homo sapiens]
(810 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505881 plasminogen [Homo sapiens] 1766 0.0
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 1078 0.0
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 487 e-137
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 473 e-133
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 462 e-130
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ... 308 1e-83
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 248 2e-65
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 248 2e-65
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s... 233 4e-61
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s... 223 6e-58
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 211 2e-54
gi|4504383 HGF activator preproprotein [Homo sapiens] 208 1e-53
gi|33695155 hepsin [Homo sapiens] 197 4e-50
gi|4504481 hepsin [Homo sapiens] 197 4e-50
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 192 8e-49
gi|13994276 marapsin [Homo sapiens] 191 2e-48
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 190 5e-48
gi|117956391 protease, serine, 33 [Homo sapiens] 189 9e-48
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 185 1e-46
gi|74048573 plasminogen-like B1 [Homo sapiens] 185 2e-46
gi|4505883 plasminogen-like B2 [Homo sapiens] 185 2e-46
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 181 3e-45
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 181 3e-45
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 180 5e-45
gi|110815798 ovochymase 1 [Homo sapiens] 180 5e-45
gi|4503137 chymotrypsin-like [Homo sapiens] 179 9e-45
gi|223942069 enterokinase precursor [Homo sapiens] 177 5e-44
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 177 5e-44
gi|118498341 chymotrypsin B1 [Homo sapiens] 176 6e-44
gi|11415040 matriptase [Homo sapiens] 174 2e-43
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 1766 bits (4574), Expect = 0.0
Identities = 810/810 (100%), Positives = 810/810 (100%)
Query: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT 60
MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
Sbjct: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT 60
Query: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN 120
CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
Sbjct: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN 120
Query: 121 GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE 180
GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
Sbjct: 121 GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE 180
Query: 181 CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE 240
CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE
Sbjct: 181 CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE 240
Query: 241 LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS 300
LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS
Sbjct: 241 LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS 300
Query: 301 AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE 360
AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE
Sbjct: 301 AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE 360
Query: 361 QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG 420
QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG
Sbjct: 361 QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG 420
Query: 421 LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED 480
LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED
Sbjct: 421 LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED 480
Query: 481 CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG 540
CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG
Sbjct: 481 CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG 540
Query: 541 PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT 600
PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT
Sbjct: 541 PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT 600
Query: 601 RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE 660
RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE
Sbjct: 601 RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE 660
Query: 661 PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ 720
PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ
Sbjct: 661 PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ 720
Query: 721 LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW 780
LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW
Sbjct: 721 LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW 780
Query: 781 GLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810
GLGCARPNKPGVYVRVSRFVTWIEGVMRNN
Sbjct: 781 GLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 1078 bits (2789), Expect = 0.0
Identities = 501/785 (63%), Positives = 576/785 (73%), Gaps = 79/785 (10%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E+ + +C G+G++YRG+ S T G TCQ WSS +PH + + +P+ GL NYCRN
Sbjct: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECE-------------------------------- 182
PD + + PWCYT DP R++YC++ +C
Sbjct: 1326 PDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTG 1384
Query: 183 -EECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
++C G++Y G +S T++G CQ+W S +PH H IP +PN L +NYCRNPD E+
Sbjct: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
Query: 242 RPWCFTTDPNKRWELCDIPRC--------TTP---------------PPSSGPTYQ-CLK 277
RPWC+T DP+ RWE C++ RC TTP PP P Q C
Sbjct: 1445 RPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYH 1504
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G +YRG + TV+G TCQ WS+ PH H RTPEN+P L ENYCRNPD + PWC+T
Sbjct: 1505 GDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCYT 1564
Query: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385
T+ VRWEYC + C + PV S E + AP E TPVV+ CYHG+GQSY
Sbjct: 1565 TDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSY 1624
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQSWSSMTPHRHQ+TPENYPN GLTMNYCRNPDAD GPWCFT DPS+R
Sbjct: 1625 RGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMDPSIR 1684
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDW 505
WEYCNL +CS TE +VVAPP V+ +P + PSE+DCMFGNGKGYRGK+ATTVTGTPCQ+W
Sbjct: 1685 WEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEW 1744
Query: 506 AAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSF 565
AAQEPHRHS F P TN AGLEKNYCRNPDGD+ GPWCYT NPRKL+DYCD+P CA+ SF
Sbjct: 1745 AAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASSSF 1804
Query: 566 DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLE 625
DCGKPQVEPKKCPG +VGGCVAHPHSWPWQVSLRTRFG HFCGGTLISPEWVLTAAHCL+
Sbjct: 1805 DCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLK 1864
Query: 626 KSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPAC 685
KS RPSSYKVILGAHQEVNLE HVQEIEVSRLFLEPT+ DIALLKLS PAVITDKV+PAC
Sbjct: 1865 KSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKVMPAC 1924
Query: 686 LPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELC 745
LPSP+Y+V RTEC+ITGWGETQGTFG GLLKEAQL VIEN+VCN Y++ +C
Sbjct: 1925 LPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKY---------IC 1975
Query: 746 AGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEG 805
A HLA GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVY RVSRFVTWIEG
Sbjct: 1976 AEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEG 2035
Query: 806 VMRNN 810
+MRNN
Sbjct: 2036 MMRNN 2040
Score = 536 bits (1381), Expect = e-152
Identities = 251/538 (46%), Positives = 325/538 (60%), Gaps = 74/538 (13%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E+ + +C G+G++YRG+ S T G TCQ WSS +PH + + +P+ GL NYCRN
Sbjct: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECE-------------------------EECMHCS 189
PD + PWCYT DP R++YC++ +C ++C H
Sbjct: 1220 PDAE-ISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
Query: 190 GENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTD 249
G++Y G S T++G CQ+W S +PH H +PN L +NYCRNPD E+RPWC+T D
Sbjct: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
Query: 250 PNKRWELCDIPRC--------TTP----------PPSSGPT------YQCLKGTGENYRG 285
P+ RWE C++ +C TTP P PT C +G G++YRG
Sbjct: 1339 PSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRG 1398
Query: 286 NVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWE 345
++ T++G TCQ WS+ TPH H R P +P L NYCRNPD + PWC+T + VRWE
Sbjct: 1399 TLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWE 1458
Query: 346 YCKIPSC---DSSPVSTEQLAPT---------APPELTPVVQDCYHGDGQSYRGTSSTTT 393
YC + C +SS ++T +AP APPE +PVVQDCYHGDG+SYRG SSTT
Sbjct: 1459 YCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTV 1518
Query: 394 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453
TG+ CQSWSSM PH HQ+TPENYPNAGLT NYCRNPD+ K PWC+TTDP VRWEYCNL +
Sbjct: 1519 TGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCYTTDPCVRWEYCNLTQ 1578
Query: 454 CSGTEASVVAPPPVVLLPDVE----------TPSEEDCMFGNGKGYRGKRATTVTGTPCQ 503
CS TE+ V+ P VV +P +E TP C GNG+ YRG +TTVTG CQ
Sbjct: 1579 CSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQ 1638
Query: 504 DWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA 561
W++ PHRH TPE P GL NYCRNPD D GPWC+T +P ++YC++ +C+
Sbjct: 1639 SWSSMTPHRHQ-RTPENYPNDGLTMNYCRNPDADT-GPWCFTMDPSIRWEYCNLTRCS 1694
Score = 526 bits (1354), Expect = e-149
Identities = 256/576 (44%), Positives = 334/576 (57%), Gaps = 90/576 (15%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E++ + EC GNG++Y+GT T G TCQ WSS +PH +PA +P+ GL +NYCRN
Sbjct: 932 EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD PWCYTTDP R++YC++ C +
Sbjct: 992 PD-PVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
+C + G++Y G S T++G CQAW S +PH H P +PN L +NYCRNPD E+
Sbjct: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
Query: 242 RPWCFTTDPNKRWELCDIPRC------------TTPPPSS------GPTYQ------CLK 277
RPWC+T DP+ RWE C++ +C P PS+ PT Q C
Sbjct: 1111 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYH 1170
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++YRG+ + TV+G TCQ WS+ TPH H RT E +P L NYCRNPD + +PWC+T
Sbjct: 1171 GDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYT 1230
Query: 338 TNSQVRWEYCKIPSC---DSSPVSTEQ-LAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT 393
+ VRWEYC + C +SS ++T ++ AP E +P VQDCYHGDGQSYRG+ STT
Sbjct: 1231 MDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTV 1290
Query: 394 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453
TG+ CQSWSSMTPH HQ+T E YPN GLT NYCRNPDA+ PWC+T DPSVRWEYCNL +
Sbjct: 1291 TGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQ 1350
Query: 454 CSGTEASVVAPPPVVLLPDVETPSEE----------DCMFGNGKGYRGKRATTVTGTPCQ 503
C E++++ P VV +P E PSEE DC G+G+ YRG +TT+TG CQ
Sbjct: 1351 CPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQ 1410
Query: 504 DWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQC--- 560
W++ PH H P P AGL +NYCRNPD ++ PWCYT +P ++YC++ +C
Sbjct: 1411 SWSSMTPHWHRRI-PLYYPNAGLTRNYCRNPDAEI-RPWCYTMDPSVRWEYCNLTRCPVT 1468
Query: 561 -----------AAPSFDCGKPQVEPKKCPGRVVGGC 585
PS + Q P+K P VV C
Sbjct: 1469 ESSVLTTPTVAPVPSTEAPSEQAPPEKSP--VVQDC 1502
Score = 515 bits (1327), Expect = e-146
Identities = 246/540 (45%), Positives = 317/540 (58%), Gaps = 74/540 (13%)
Query: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
L E+ + +C G++YRGT S T G TCQ WSS +PH+ +P +P+ GL NYC
Sbjct: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
Query: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILEC------------------------------- 181
RNPD + + PWCYT DP R++YC++ +C
Sbjct: 1104 RNPDAEIR-PWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
Query: 182 --EEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDR 239
++C H G++Y G S T++G CQ+W S +PH H +PN L +NYCRNPD
Sbjct: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
Query: 240 ELRPWCFTTDPNKRWELCDIPRCTT---------------PPPSSGPTYQ-CLKGTGENY 283
E+ PWC+T DPN RWE C++ +C P PT Q C G G++Y
Sbjct: 1223 EISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSY 1282
Query: 284 RGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVR 343
RG+ + TV+G TCQ WS+ TPH H RT E +P L NYCRNPD + PWC+T + VR
Sbjct: 1283 RGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVR 1342
Query: 344 WEYCKIPSC---DSSPVSTEQLAPT---------APPELTPVVQDCYHGDGQSYRGTSST 391
WEYC + C +S+ ++T + P AP E + VQDCY GDGQSYRGT ST
Sbjct: 1343 WEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLST 1402
Query: 392 TTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNL 451
T TG+ CQSWSSMTPH H++ P YPNAGLT NYCRNPDA+ PWC+T DPSVRWEYCNL
Sbjct: 1403 TITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNL 1462
Query: 452 KKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRATTVTGTP 501
+C TE+SV+ P V +P E PSE +DC G+G+ YRG +TTVTG
Sbjct: 1463 TRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRT 1522
Query: 502 CQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA 561
CQ W++ PH H TPE P AGL +NYCRNPD PWCYTT+P ++YC++ QC+
Sbjct: 1523 CQSWSSMIPHWHQ-RTPENYPNAGLTENYCRNPDSG-KQPWCYTTDPCVRWEYCNLTQCS 1580
Score = 514 bits (1325), Expect = e-146
Identities = 256/560 (45%), Positives = 324/560 (57%), Gaps = 83/560 (14%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E++ + EC GNG++YRGT S T G TCQ WSS +PH +P +P+ GL NYCRN
Sbjct: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD P+CYT DP R++YC++ +C +
Sbjct: 194 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
EC H +G++Y G S T++G CQAW S +PH+H P +PN L NYCRNPD
Sbjct: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
Query: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277
P+C+T DP RWE C++ +C+ TP PS PT Q C
Sbjct: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++YRG + TV+G TCQ WS+ TPH+H+RTPE +P L NYCRNPD AP+C+T
Sbjct: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
Query: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385
+ VRWEYC + C + PV S E + AP E P VQ+CYHG+GQSY
Sbjct: 433 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 492
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA P+C+T DP VR
Sbjct: 493 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 552
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495
WEYCNL +CS E + VAPP V +P +E PSE ++C GNG+ YRG +T
Sbjct: 553 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 612
Query: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555
TVTG CQ W++ PH HS TPE P AGL NYCRNPD V P+CYT +P ++YC
Sbjct: 613 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 670
Query: 556 DVPQCA-APSFDCGKPQVEP 574
++ QC+ A P V P
Sbjct: 671 NLTQCSDAEGTAVAPPTVTP 690
Score = 514 bits (1325), Expect = e-146
Identities = 256/560 (45%), Positives = 324/560 (57%), Gaps = 83/560 (14%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E++ + EC GNG++YRGT S T G TCQ WSS +PH +P +P+ GL NYCRN
Sbjct: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD P+CYT DP R++YC++ +C +
Sbjct: 308 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
EC H +G++Y G S T++G CQAW S +PH+H P +PN L NYCRNPD
Sbjct: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
Query: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277
P+C+T DP RWE C++ +C+ TP PS PT Q C
Sbjct: 427 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 486
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++YRG + TV+G TCQ WS+ TPH+H+RTPE +P L NYCRNPD AP+C+T
Sbjct: 487 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 546
Query: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385
+ VRWEYC + C + PV S E + AP E P VQ+CYHG+GQSY
Sbjct: 547 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 606
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA P+C+T DP VR
Sbjct: 607 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 666
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495
WEYCNL +CS E + VAPP V +P +E PSE ++C GNG+ YRG +T
Sbjct: 667 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 726
Query: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555
TVTG CQ W++ PH HS TPE P AGL NYCRNPD V P+CYT +P ++YC
Sbjct: 727 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 784
Query: 556 DVPQCA-APSFDCGKPQVEP 574
++ QC+ A P V P
Sbjct: 785 NLTQCSDAEGTAVAPPTVTP 804
Score = 514 bits (1324), Expect = e-145
Identities = 252/546 (46%), Positives = 320/546 (58%), Gaps = 82/546 (15%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E++ + EC GNG++YRGT S T G TCQ WSS +PH +P +P+ GL NYCRN
Sbjct: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD P+CYT DP R++YC++ +C +
Sbjct: 422 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
EC H +G++Y G S T++G CQAW S +PH+H P +PN L NYCRNPD
Sbjct: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
Query: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277
P+C+T DP RWE C++ +C+ TP PS PT Q C
Sbjct: 541 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++YRG + TV+G TCQ WS+ TPH+H+RTPE +P L NYCRNPD AP+C+T
Sbjct: 601 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
Query: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385
+ VRWEYC + C + PV S E + AP E P VQ+CYHG+GQSY
Sbjct: 661 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 720
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA P+C+T DP VR
Sbjct: 721 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 780
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495
WEYCNL +CS E + VAPP V +P +E PSE ++C GNG+ YRG +T
Sbjct: 781 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 840
Query: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555
TVTG CQ W++ PH HS TPE P AGL NYCRNPD V P+CYT +P ++YC
Sbjct: 841 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPD-PVAAPYCYTRDPSVRWEYC 898
Query: 556 DVPQCA 561
++ QC+
Sbjct: 899 NLTQCS 904
Score = 514 bits (1323), Expect = e-145
Identities = 259/587 (44%), Positives = 331/587 (56%), Gaps = 98/587 (16%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E++ + EC GNG++YRGT S T G TCQ WSS +PH +P +P+ GL NYCRN
Sbjct: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD P+CYT DP R++YC++ +C +
Sbjct: 536 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
EC H +G++Y G S T++G CQAW S +PH+H P +PN L NYCRNPD
Sbjct: 595 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
Query: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277
P+C+T DP RWE C++ +C+ TP PS PT Q C
Sbjct: 655 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 714
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++YRG + TV+G TCQ WS+ TPH+H+RTPE +P L NYCRNPD AP+C+T
Sbjct: 715 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 774
Query: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385
+ VRWEYC + C + PV S E + AP E P VQ+CYHG+GQSY
Sbjct: 775 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 834
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPD P+C+T DPSVR
Sbjct: 835 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVR 894
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495
WEYCNL +CS E + VAPP + +P +E PSE ++C GNG+ Y+G
Sbjct: 895 WEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFI 954
Query: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555
TVTG CQ W++ PH HS TP P AGL KNYCRNPD V PWCYTT+P ++YC
Sbjct: 955 TVTGRTCQAWSSMTPHSHS-RTPAYYPNAGLIKNYCRNPD-PVAAPWCYTTDPSVRWEYC 1012
Query: 556 DVPQCA--------------APSFDCGKPQVEPKKCPGRVVGGCVAH 588
++ +C+ APS + Q ++ PG V C H
Sbjct: 1013 NLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG--VQDCYYH 1057
Score = 510 bits (1313), Expect = e-144
Identities = 253/560 (45%), Positives = 323/560 (57%), Gaps = 83/560 (14%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E+ + +C G+G++YRGT S T G TCQ WSS +PH+ + +P+ GL NYCRN
Sbjct: 20 EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD P+CYT DP R++YC++ +C +
Sbjct: 80 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
EC H +G++Y G S T++G CQAW S +PH+H P +PN L NYCRNPD
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277
P+C+T DP RWE C++ +C+ TP PS PT Q C
Sbjct: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++YRG + TV+G TCQ WS+ TPH+H+RTPE +P L NYCRNPD AP+C+T
Sbjct: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
Query: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385
+ VRWEYC + C + PV S E + AP E P VQ+CYHG+GQSY
Sbjct: 319 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 378
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA P+C+T DP VR
Sbjct: 379 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 438
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495
WEYCNL +CS E + VAPP V +P +E PSE ++C GNG+ YRG +T
Sbjct: 439 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 498
Query: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555
TVTG CQ W++ PH HS TPE P AGL NYCRNPD V P+CYT +P ++YC
Sbjct: 499 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 556
Query: 556 DVPQCA-APSFDCGKPQVEP 574
++ QC+ A P V P
Sbjct: 557 NLTQCSDAEGTAVAPPTVTP 576
Score = 508 bits (1308), Expect = e-144
Identities = 249/545 (45%), Positives = 317/545 (58%), Gaps = 82/545 (15%)
Query: 95 EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154
E++ + EC GNG++YRGT S T G TCQ WSS +PH +P +P+ GL NYCRN
Sbjct: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
Query: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183
PD P+CYT DP R++YC++ +C +
Sbjct: 764 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
Query: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241
EC H +G++Y G S T++G CQAW S +PH+H P +PN L NYCRNPD
Sbjct: 823 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
Query: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277
P+C+T DP+ RWE C++ +C+ TP PS PT Q C
Sbjct: 883 APYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYH 942
Query: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337
G G++Y+G +TV+G TCQ WS+ TPH+H+RTP +P L +NYCRNPD APWC+T
Sbjct: 943 GNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYT 1002
Query: 338 TNSQVRWEYCKIPSCDSSP------------VSTEQLAPTAPPELTPVVQDCYHGDGQSY 385
T+ VRWEYC + C + S E A E TP VQDCY+ GQSY
Sbjct: 1003 TDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSY 1062
Query: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445
RGT STT TG+ CQ+WSSMTPH+H +TPENYPNAGLT NYCRNPDA+ PWC+T DPSVR
Sbjct: 1063 RGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVR 1122
Query: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEE----------DCMFGNGKGYRGKRAT 495
WEYCNL +C TE+SV+A VV P E SEE DC G+G+ YRG +T
Sbjct: 1123 WEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFST 1182
Query: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555
TVTG CQ W++ PH H T E P GL +NYCRNPD ++ PWCYT +P ++YC
Sbjct: 1183 TVTGRTCQSWSSMTPHWHQ-RTTEYYPNGGLTRNYCRNPDAEI-SPWCYTMDPNVRWEYC 1240
Query: 556 DVPQC 560
++ QC
Sbjct: 1241 NLTQC 1245
Score = 357 bits (917), Expect = 2e-98
Identities = 172/332 (51%), Positives = 208/332 (62%), Gaps = 25/332 (7%)
Query: 266 PPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCR 325
P S C G G++YRG + TV+G TCQ WS+ TPH HNRT EN+P L NYCR
Sbjct: 19 PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
Query: 326 NPDGKRAPWCHTTNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPV 373
NPD AP+C+T + VRWEYC + C + PV S E + AP E P
Sbjct: 79 NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433
VQ+CYHG+GQSYRGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 434 GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMF 483
P+C+T DP VRWEYCNL +CS E + VAPP V +P +E PSE ++C
Sbjct: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
Query: 484 GNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWC 543
GNG+ YRG +TTVTG CQ W++ PH HS TPE P AGL NYCRNPD V P+C
Sbjct: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYC 316
Query: 544 YTTNPRKLYDYCDVPQCA-APSFDCGKPQVEP 574
YT +P ++YC++ QC+ A P V P
Sbjct: 317 YTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 348
Score = 265 bits (677), Expect = 1e-70
Identities = 125/221 (56%), Positives = 150/221 (67%), Gaps = 13/221 (5%)
Query: 365 TAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMN 424
+A PE + VVQDCYHGDGQSYRGT STT TG+ CQ+WSSMTPH+H +T ENYPNAGL MN
Sbjct: 16 SAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMN 75
Query: 425 YCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE------ 478
YCRNPDA P+C+T DP VRWEYCNL +CS E + VAPP V +P +E PSE
Sbjct: 76 YCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQ 135
Query: 479 ----EDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 534
++C GNG+ YRG +TTVTG CQ W++ PH HS TPE P AGL NYCRNP
Sbjct: 136 RPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNP 194
Query: 535 DGDVGGPWCYTTNPRKLYDYCDVPQCA-APSFDCGKPQVEP 574
D V P+CYT +P ++YC++ QC+ A P V P
Sbjct: 195 DA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 234
Score = 34.3 bits (77), Expect = 0.48
Identities = 17/20 (85%), Positives = 17/20 (85%)
Query: 1 MEHKEVVLLLLLFLKSGQGE 20
MEHKEVVLLLLLFLKS E
Sbjct: 1 MEHKEVVLLLLLFLKSAAPE 20
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 487 bits (1253), Expect = e-137
Identities = 261/661 (39%), Positives = 354/661 (53%), Gaps = 67/661 (10%)
Query: 171 KRYDYCDILECEE---ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNK 227
+R CD+ + ++ C+ +G Y G ++ T+ GL CQAW + P+ H Y P+
Sbjct: 107 RRSGRCDLFQKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RN 164
Query: 228 NLKKNYCRNPDRELR-PWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGN 286
L++N+CRNPD + PWC+TTDP R++ C I C C+ GE YRG
Sbjct: 165 GLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAA--------CVWCNGEEYRGA 216
Query: 287 VAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEY 346
V T SG CQ W Q PH H P F + LD+NYCRNPDG PWC+TT+ Q+ E+
Sbjct: 217 VDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREF 276
Query: 347 CKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTP 406
C +P C S A P C+ G G+ YRGT++TTT G CQ W + P
Sbjct: 277 CDLPRCGSE----------AQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIP 326
Query: 407 HRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYC-NLKKCSGTEASVVAPP 465
H+H+ TPE Y L N+CRNPD + PWCFT P +R +C +++C+ V P
Sbjct: 327 HQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRCTDD----VRP- 381
Query: 466 PVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAG 525
+DC G G+ YRG + T G CQ W+A+ PH+ FT + P A
Sbjct: 382 -------------QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQ-FTFTSEPHAQ 427
Query: 526 LEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA---APSF----------DCGK--P 570
LE+N+CRNPDGD GPWCYT +PR +DYC + +CA PS CGK
Sbjct: 428 LEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQVQFEKCGKRVD 487
Query: 571 QVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRP 630
+++ ++ RVVGG HP + PW VSLR R G HFCGG+L+ +W+LTA C P
Sbjct: 488 RLDQRRSKLRVVGG---HPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMP 544
Query: 631 -SSYKVILGA--HQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLP 687
+ Y+V LG + EP +Q + V+++ P+ + LLKL + +V CLP
Sbjct: 545 LTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVALICLP 604
Query: 688 SPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAG 747
YVV T+C I GWGET+GT +L A L VI N+ CN GRV+ +E+C
Sbjct: 605 PEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKH--RGRVRESEMCTE 662
Query: 748 HLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
L +C+GD GGPL CF + ++L+G+ CAR P V+ RVS FV WI VM
Sbjct: 663 GLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 722
Query: 808 R 808
R
Sbjct: 723 R 723
Score = 406 bits (1043), Expect = e-113
Identities = 201/463 (43%), Positives = 256/463 (55%), Gaps = 33/463 (7%)
Query: 17 GQGEPLDDYVNTQGASLFSVTKK------QLGAGSIEECAAKCEEDEEFTCRAFQYHSKE 70
GQ PL+D+ +G L + Q EECA +C CRAF Y+
Sbjct: 32 GQRSPLNDFQVLRGTELQHLLHAVVPGPWQEDVADAEECAGRC--GPLMDCRAFHYNVSS 89
Query: 71 QQCVIMAENRKS--SIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWS 128
C ++ + S + + R LF+KK Y+ C NG YRGTM+ T G+ CQ WS
Sbjct: 90 HGCQLLPWTQHSPHTRLRRSGRCDLFQKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWS 149
Query: 129 STSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEE-CMH 187
P+ +++P GLEEN+CRNPD DP GPWCYTTDP R+ C I C E C+
Sbjct: 150 HKFPNDHKYTPTLR--NGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVW 207
Query: 188 CSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFT 247
C+GE Y G + +T SG ECQ WD Q PH H + P KF ++ L NYCRNPD RPWC+T
Sbjct: 208 CNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYT 267
Query: 248 TDPNKRWELCDIPRC--TTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPH 305
TDP E CD+PRC P T C +G GE YRG T +G CQ W AQ PH
Sbjct: 268 TDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPH 327
Query: 306 THNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYC-KIPSCDSSPVSTEQLAP 364
H TPE + CK+L EN+CRNPDG APWC T +R +C +I C T+ + P
Sbjct: 328 QHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRC------TDDVRP 381
Query: 365 TAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMN 424
QDCYHG G+ YRGT S T G +CQ WS+ TPH+ Q T + P+A L N
Sbjct: 382 ----------QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEEN 431
Query: 425 YCRNPDADK-GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPP 466
+CRNPD D GPWC+T DP ++YC L++C+ + + PP
Sbjct: 432 FCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPP 474
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 473 bits (1218), Expect = e-133
Identities = 248/633 (39%), Positives = 341/633 (53%), Gaps = 50/633 (7%)
Query: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
C+ G +Y G +S T SG++CQ W S PH H ++PS + K+L++NYCRNP E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 188 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 239
Query: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLA 363
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C + ++ +
Sbjct: 240 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDV- 298
Query: 364 PTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM 423
P E T +C G G+ YRGT +T G CQ W S PH H TPEN+ L
Sbjct: 299 ---PLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRE 351
Query: 424 NYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMF 483
NYCRNPD + PWCFTTDP++R YC+ +P+ + +DC
Sbjct: 352 NYCRNPDGSESPWCFTTDPNIRVGYCSQ------------------IPNCDMSHGQDCYR 393
Query: 484 GNGKGYRGKRATTVTGTPCQDWAA--QEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGP 541
GNGK Y G + T +G C W ++ HRH + P+ + L +NYCRNPD D GP
Sbjct: 394 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK---LNENYCRNPDDDAHGP 450
Query: 542 WCYTTNPRKLYDYCDVPQCAAPS----FDCGKPQVEPKKCPG-RVVGGCVAHPHSWPWQV 596
WCYT NP +DYC + +C + + P + K RVV G + W V
Sbjct: 451 WCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIG-WMV 509
Query: 597 SLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNL--EPHVQEIEV 654
SLR R H CGG+LI WVLTA C S Y+ LG H E Q + V
Sbjct: 510 SLRYR-NKHICGGSLIKESWVLTARQCFP-SRDLKDYEAWLGIHDVHGRGDEKCKQVLNV 567
Query: 655 SRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAG 714
S+L P D+ L+KL+ PAV+ D V LP+ + ++T C + GWG T G
Sbjct: 568 SQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDG 627
Query: 715 LLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYIL 774
LL+ A L ++ N+ C+++ + +E+CAG G+ C+GD GGPLVC + ++
Sbjct: 628 LLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMV 687
Query: 775 QGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
GV G GCA PN+PG++VRV+ + WI ++
Sbjct: 688 LGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 720
Score = 395 bits (1016), Expect = e-110
Identities = 187/431 (43%), Positives = 255/431 (59%), Gaps = 31/431 (7%)
Query: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
Query: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH F P+++ + L+ENYC
Sbjct: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177
Query: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 178 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 237
Query: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRC--TTPPPSS 269
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T +
Sbjct: 238 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTD 297
Query: 270 GP--TYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNP 327
P T +C++G GE YRG V +G CQ W +Q PH H+ TPENF CK+L ENYCRNP
Sbjct: 298 VPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNP 357
Query: 328 DGKRAPWCHTTNSQVRWEYC-KIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYR 386
DG +PWC TT+ +R YC +IP+CD S QDCY G+G++Y
Sbjct: 358 DGSESPWCFTTDPNIRVGYCSQIPNCDMSH-----------------GQDCYRGNGKNYM 400
Query: 387 GTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVR 445
G S T +G C W H+ + L NYCRNPD D GPWC+T +P +
Sbjct: 401 GNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIP 460
Query: 446 WEYCNLKKCSG 456
W+YC + +C G
Sbjct: 461 WDYCPISRCEG 471
Score = 102 bits (255), Expect = 1e-21
Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 16/129 (12%)
Query: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
+C+ G G+ Y+G + T +G CQ W++ PH HS F P + L++NYCRNP G+ G
Sbjct: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEEG 185
Query: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 186 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 236
Query: 594 WQVSLRTRF 602
Q R +F
Sbjct: 237 HQTPHRHKF 245
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 462 bits (1190), Expect = e-130
Identities = 247/633 (39%), Positives = 337/633 (53%), Gaps = 55/633 (8%)
Query: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
C+ G +Y G +S T SG++CQ W S PH H Y K+L++NYCRNP E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSY-----RGKDLQENYCRNPRGEEGGP 182
Query: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 183 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 234
Query: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLA 363
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C + ++ +
Sbjct: 235 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDV- 293
Query: 364 PTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM 423
P E T +C G G+ YRGT +T G CQ W S PH H TPEN+ L
Sbjct: 294 ---PLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRE 346
Query: 424 NYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMF 483
NYCRNPD + PWCFTTDP++R YC+ +P+ + +DC
Sbjct: 347 NYCRNPDGSESPWCFTTDPNIRVGYCSQ------------------IPNCDMSHGQDCYR 388
Query: 484 GNGKGYRGKRATTVTGTPCQDWAA--QEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGP 541
GNGK Y G + T +G C W ++ HRH + P+ + L +NYCRNPD D GP
Sbjct: 389 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK---LNENYCRNPDDDAHGP 445
Query: 542 WCYTTNPRKLYDYCDVPQCAAPS----FDCGKPQVEPKKCPG-RVVGGCVAHPHSWPWQV 596
WCYT NP +DYC + +C + + P + K RVV G + W V
Sbjct: 446 WCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIG-WMV 504
Query: 597 SLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNL--EPHVQEIEV 654
SLR R H CGG+LI WVLTA C S Y+ LG H E Q + V
Sbjct: 505 SLRYR-NKHICGGSLIKESWVLTARQCFP-SRDLKDYEAWLGIHDVHGRGDEKCKQVLNV 562
Query: 655 SRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAG 714
S+L P D+ L+KL+ PAV+ D V LP+ + ++T C + GWG T G
Sbjct: 563 SQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDG 622
Query: 715 LLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYIL 774
LL+ A L ++ N+ C+++ + +E+CAG G+ C+GD GGPLVC + ++
Sbjct: 623 LLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMV 682
Query: 775 QGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
GV G GCA PN+PG++VRV+ + WI ++
Sbjct: 683 LGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
Score = 385 bits (989), Expect = e-107
Identities = 185/431 (42%), Positives = 251/431 (58%), Gaps = 36/431 (8%)
Query: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
Query: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH + + L+ENYC
Sbjct: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENYC 172
Query: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 173 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 232
Query: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRC--TTPPPSS 269
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T +
Sbjct: 233 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTD 292
Query: 270 GP--TYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNP 327
P T +C++G GE YRG V +G CQ W +Q PH H+ TPENF CK+L ENYCRNP
Sbjct: 293 VPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNP 352
Query: 328 DGKRAPWCHTTNSQVRWEYC-KIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYR 386
DG +PWC TT+ +R YC +IP+CD S QDCY G+G++Y
Sbjct: 353 DGSESPWCFTTDPNIRVGYCSQIPNCDMSH-----------------GQDCYRGNGKNYM 395
Query: 387 GTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVR 445
G S T +G C W H+ + L NYCRNPD D GPWC+T +P +
Sbjct: 396 GNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIP 455
Query: 446 WEYCNLKKCSG 456
W+YC + +C G
Sbjct: 456 WDYCPISRCEG 466
Score = 97.1 bits (240), Expect = 6e-20
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
+C+ G G+ Y+G + T +G CQ W++ PH HS + L++NYCRNP G+ G
Sbjct: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKD------LQENYCRNPRGEEG 180
Query: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 231
Query: 594 WQVSLRTRF 602
Q R +F
Sbjct: 232 HQTPHRHKF 240
>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
sapiens]
Length = 299
Score = 308 bits (790), Expect = 1e-83
Identities = 162/309 (52%), Positives = 187/309 (60%), Gaps = 44/309 (14%)
Query: 530 YCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHP 589
YCRNPDGD+ GPWCY NPRKL+DYCD+P CA+ SFDCGKPQVEPKKCP +VGGCVAHP
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPRSIVGGCVAHP 66
Query: 590 HSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHV 649
HSWPWQVSL T + A L P+ S V + N H+
Sbjct: 67 HSWPWQVSLTT--------------SKAVPAQRAL--GPQASKKPVEVTESLNHNFSVHI 110
Query: 650 QEIEVSRLFLEPTRKDIALLKLS-----------SPAVITDKVIPACLPSPNYVVADRTE 698
+ + + +A+ KL + +T P P +VA R+
Sbjct: 111 ASQYALTIIIPISLTPLAVGKLKLLMSQFRFLRGAGCSLTHLHSPRHAPPARCLVARRSF 170
Query: 699 CFIT------GWGETQGT-----------FGAGLLKEAQLPVIENKVCNRYEFLNGRVQS 741
W G+ G ++ QL VIENKVCNRYE+LNGR++S
Sbjct: 171 LHAAPSRLGLSWALEPGSGKSLFYAAHVPLGLAFSRKPQLLVIENKVCNRYEYLNGRIKS 230
Query: 742 TELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVT 801
TELCA HLAGGTDSC+GDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVT
Sbjct: 231 TELCARHLAGGTDSCKGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVT 290
Query: 802 WIEGVMRNN 810
WIEGVMRNN
Sbjct: 291 WIEGVMRNN 299
Score = 57.8 bits (138), Expect = 4e-08
Identities = 22/46 (47%), Positives = 25/46 (54%)
Query: 151 YCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGK 196
YCRNPD D GPWCY +P K +DYCDI C C + K
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASSSFDCGKPQVEPK 52
Score = 45.4 bits (106), Expect = 2e-04
Identities = 16/33 (48%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
Query: 233 YCRNPDRELR-PWCFTTDPNKRWELCDIPRCTT 264
YCRNPD ++ PWC+ +P K ++ CDIP C +
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCAS 39
Score = 45.1 bits (105), Expect = 3e-04
Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 YCRNPDGK-RAPWCHTTNSQVRWEYCKIPSCDSS 355
YCRNPDG PWC+ N + ++YC IP C SS
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40
Score = 43.9 bits (102), Expect = 6e-04
Identities = 15/34 (44%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 425 YCRNPDAD-KGPWCFTTDPSVRWEYCNLKKCSGT 457
YCRNPD D GPWC+ +P ++YC++ C+ +
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 248 bits (632), Expect = 2e-65
Identities = 168/465 (36%), Positives = 221/465 (47%), Gaps = 63/465 (13%)
Query: 377 CYHGDGQSYRGTSSTTTTGKKCQSWSSMT----PHRHQKTPENYPNAGLTMNYCRNPDAD 432
CY G SYRGT ST +G +C +W+S P+ ++ G NYCRNPD D
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLG-NHNYCRNPDRD 185
Query: 433 KGPWCFTTDPS-VRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRG 491
PWC+ E+C+ CS DC FGNG YRG
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACS--------------------EGNSDCYFGNGSAYRG 225
Query: 492 KRATTVTGTPCQDWAAQEPHRHSIFTPETNPRA---GLEK-NYCRNPDGDVGGPWCYTTN 547
+ T +G C W + ++T + NP A GL K NYCRNPDGD PWC+
Sbjct: 226 THSLTESGASCLPWNSMILIG-KVYTAQ-NPSAQALGLGKHNYCRNPDGDAK-PWCHVLK 282
Query: 548 PRKL-YDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSL----RTRF 602
R+L ++YCDVP C+ CG Q + R+ GG A S PWQ ++ R
Sbjct: 283 NRRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAIFAKHRRSP 336
Query: 603 GMHF-CGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFL-- 659
G F CGG LIS W+L+AAHC ++ P VILG V Q+ EV + +
Sbjct: 337 GERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHK 396
Query: 660 ----EPTRKDIALLKLSSP----AVITDKVIPACLPSPNYVVADRTECFITGWG--ETQG 709
+ DIALL+L S A + V CLP + + D TEC ++G+G E
Sbjct: 397 EFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALS 456
Query: 710 TFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGT------DSCQGDSGGP 763
F + LKEA + + + C LN V LCAG G D+CQGDSGGP
Sbjct: 457 PFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGP 516
Query: 764 LVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMR 808
LVC + L G+ SWGLGC + + PGVY +V+ ++ WI MR
Sbjct: 517 LVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 561
Score = 116 bits (290), Expect = 1e-25
Identities = 69/195 (35%), Positives = 89/195 (45%), Gaps = 16/195 (8%)
Query: 169 PEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDS----QSPHAHGYIPSKF 224
PE C ++ C G +Y G S SG EC W+S Q P++ G P
Sbjct: 111 PEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAI 169
Query: 225 PNKNLKKNYCRNPDRELRPWCFTTDPNK-RWELCDIPRCTTPPPSSGPTYQCLKGTGENY 283
NYCRNPDR+ +PWC+ K E C P C S C G G Y
Sbjct: 170 RLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPAC------SEGNSDCYFGNGSAY 223
Query: 284 RGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNL---DENYCRNPDGKRAPWCHT-TN 339
RG ++T SG +C W++ T +N + L NYCRNPDG PWCH N
Sbjct: 224 RGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKN 283
Query: 340 SQVRWEYCKIPSCDS 354
++ WEYC +PSC +
Sbjct: 284 RRLTWEYCDVPSCST 298
Score = 113 bits (283), Expect = 6e-25
Identities = 64/190 (33%), Positives = 88/190 (46%), Gaps = 28/190 (14%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWS----AQTPHTHNRTPENFPCKNLDENYCRNPDGK 330
C + G +YRG + SG C +W+ AQ P++ R P+ + NYCRNPD
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRD 185
Query: 331 RAPWCHTTNS-QVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTS 389
PWC+ + + E+C P+C DCY G+G +YRGT
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEGN------------------SDCYFGNGSAYRGTH 227
Query: 390 STTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM---NYCRNPDADKGPWCFT-TDPSVR 445
S T +G C W+SM T +N L + NYCRNPD D PWC + +
Sbjct: 228 SLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLT 287
Query: 446 WEYCNLKKCS 455
WEYC++ CS
Sbjct: 288 WEYCDVPSCS 297
Score = 107 bits (268), Expect = 3e-23
Identities = 77/238 (32%), Positives = 105/238 (44%), Gaps = 30/238 (12%)
Query: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTS----PHRPRFSPATHPSEGLEENYCRNPDND 158
C G +YRGT S ++G C W+S++ P+ R A G NYCRNPD D
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLG-NHNYCRNPDRD 185
Query: 159 PQGPWCYTTDPEK-RYDYCDILECEE---ECMHCSGENYDGKISKTMSGLECQAWDSQSP 214
+ PWCY K ++C C E +C +G Y G S T SG C W+S
Sbjct: 186 SK-PWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMIL 244
Query: 215 HAHGYIPSKFPNKNL---KKNYCRNPDRELRPWCFTTDPNKR--WELCDIPRCTT--PPP 267
Y + L K NYCRNPD + +PWC N+R WE CD+P C+T
Sbjct: 245 IGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVL-KNRRLTWEYCDVPSCSTCGLRQ 303
Query: 268 SSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTP-ENFPCKNLDENYC 324
S P ++ +G + ++ H W A H R+P E F C + + C
Sbjct: 304 YSQPQFR--------IKGGLFADIASHP---WQAAIFAKHRRSPGERFLCGGILISSC 350
Score = 63.2 bits (152), Expect = 1e-09
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Query: 101 SECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGL---EENYCRNPDN 157
S+C GNG YRGT S T++G +C W+S ++ ++ L + NYCRNPD
Sbjct: 213 SDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG 272
Query: 158 DPQGPWCYTTDPEK-RYDYCDILEC 181
D + PWC+ + ++YCD+ C
Sbjct: 273 DAK-PWCHVLKNRRLTWEYCDVPSC 296
Score = 54.7 bits (130), Expect = 3e-07
Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 474 ETPSEEDCMFGNGKGYRGKRATTVTGTPCQDW----AAQEPHRHSIFTPETNPRAGL-EK 528
E + C G YRG +T +G C +W AQ+P +S P+ R GL
Sbjct: 120 EIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKP--YSGRRPDA-IRLGLGNH 176
Query: 529 NYCRNPDGDVGGPWCYTTNPRKL-YDYCDVPQCAAPSFDC 567
NYCRNPD D PWCY K ++C P C+ + DC
Sbjct: 177 NYCRNPDRD-SKPWCYVFKAGKYSSEFCSTPACSEGNSDC 215
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 248 bits (632), Expect = 2e-65
Identities = 168/465 (36%), Positives = 221/465 (47%), Gaps = 63/465 (13%)
Query: 377 CYHGDGQSYRGTSSTTTTGKKCQSWSSMT----PHRHQKTPENYPNAGLTMNYCRNPDAD 432
CY G SYRGT ST +G +C +W+S P+ ++ G NYCRNPD D
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLG-NHNYCRNPDRD 139
Query: 433 KGPWCFTTDPS-VRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRG 491
PWC+ E+C+ CS DC FGNG YRG
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACS--------------------EGNSDCYFGNGSAYRG 179
Query: 492 KRATTVTGTPCQDWAAQEPHRHSIFTPETNPRA---GLEK-NYCRNPDGDVGGPWCYTTN 547
+ T +G C W + ++T + NP A GL K NYCRNPDGD PWC+
Sbjct: 180 THSLTESGASCLPWNSMILIG-KVYTAQ-NPSAQALGLGKHNYCRNPDGDAK-PWCHVLK 236
Query: 548 PRKL-YDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSL----RTRF 602
R+L ++YCDVP C+ CG Q + R+ GG A S PWQ ++ R
Sbjct: 237 NRRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAIFAKHRRSP 290
Query: 603 GMHF-CGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFL-- 659
G F CGG LIS W+L+AAHC ++ P VILG V Q+ EV + +
Sbjct: 291 GERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHK 350
Query: 660 ----EPTRKDIALLKLSSP----AVITDKVIPACLPSPNYVVADRTECFITGWG--ETQG 709
+ DIALL+L S A + V CLP + + D TEC ++G+G E
Sbjct: 351 EFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALS 410
Query: 710 TFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGT------DSCQGDSGGP 763
F + LKEA + + + C LN V LCAG G D+CQGDSGGP
Sbjct: 411 PFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGP 470
Query: 764 LVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMR 808
LVC + L G+ SWGLGC + + PGVY +V+ ++ WI MR
Sbjct: 471 LVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 515
Score = 118 bits (295), Expect = 3e-26
Identities = 78/233 (33%), Positives = 100/233 (42%), Gaps = 23/233 (9%)
Query: 136 RFSPATHPSEGLEENYCRNPDNDPQGPWCYTTD-----PEKRYDYCDILECEEECMHCSG 190
RF +G E C N Q Y +D PE C ++ C G
Sbjct: 29 RFRRGARSYQGCSEPRCFNGGTCQQA--LYFSDFVCQCPEGFAGKCCEIDTRATCYEDQG 86
Query: 191 ENYDGKISKTMSGLECQAWDS----QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCF 246
+Y G S SG EC W+S Q P++ G P NYCRNPDR+ +PWC+
Sbjct: 87 ISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRDSKPWCY 145
Query: 247 TTDPNK-RWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPH 305
K E C P C S C G G YRG ++T SG +C W++
Sbjct: 146 VFKAGKYSSEFCSTPAC------SEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 199
Query: 306 THNRTPENFPCKNL---DENYCRNPDGKRAPWCHT-TNSQVRWEYCKIPSCDS 354
T +N + L NYCRNPDG PWCH N ++ WEYC +PSC +
Sbjct: 200 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST 252
Score = 113 bits (283), Expect = 6e-25
Identities = 64/190 (33%), Positives = 88/190 (46%), Gaps = 28/190 (14%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWS----AQTPHTHNRTPENFPCKNLDENYCRNPDGK 330
C + G +YRG + SG C +W+ AQ P++ R P+ + NYCRNPD
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRD 139
Query: 331 RAPWCHTTNS-QVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTS 389
PWC+ + + E+C P+C DCY G+G +YRGT
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEGN------------------SDCYFGNGSAYRGTH 181
Query: 390 STTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM---NYCRNPDADKGPWCFT-TDPSVR 445
S T +G C W+SM T +N L + NYCRNPD D PWC + +
Sbjct: 182 SLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLT 241
Query: 446 WEYCNLKKCS 455
WEYC++ CS
Sbjct: 242 WEYCDVPSCS 251
Score = 107 bits (268), Expect = 3e-23
Identities = 77/238 (32%), Positives = 105/238 (44%), Gaps = 30/238 (12%)
Query: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTS----PHRPRFSPATHPSEGLEENYCRNPDND 158
C G +YRGT S ++G C W+S++ P+ R A G NYCRNPD D
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLG-NHNYCRNPDRD 139
Query: 159 PQGPWCYTTDPEK-RYDYCDILECEE---ECMHCSGENYDGKISKTMSGLECQAWDSQSP 214
+ PWCY K ++C C E +C +G Y G S T SG C W+S
Sbjct: 140 SK-PWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMIL 198
Query: 215 HAHGYIPSKFPNKNL---KKNYCRNPDRELRPWCFTTDPNKR--WELCDIPRCTT--PPP 267
Y + L K NYCRNPD + +PWC N+R WE CD+P C+T
Sbjct: 199 IGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVL-KNRRLTWEYCDVPSCSTCGLRQ 257
Query: 268 SSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTP-ENFPCKNLDENYC 324
S P ++ +G + ++ H W A H R+P E F C + + C
Sbjct: 258 YSQPQFR--------IKGGLFADIASHP---WQAAIFAKHRRSPGERFLCGGILISSC 304
Score = 63.2 bits (152), Expect = 1e-09
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Query: 101 SECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGL---EENYCRNPDN 157
S+C GNG YRGT S T++G +C W+S ++ ++ L + NYCRNPD
Sbjct: 167 SDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG 226
Query: 158 DPQGPWCYTTDPEK-RYDYCDILEC 181
D + PWC+ + ++YCD+ C
Sbjct: 227 DAK-PWCHVLKNRRLTWEYCDVPSC 250
Score = 54.7 bits (130), Expect = 3e-07
Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 474 ETPSEEDCMFGNGKGYRGKRATTVTGTPCQDW----AAQEPHRHSIFTPETNPRAGL-EK 528
E + C G YRG +T +G C +W AQ+P +S P+ R GL
Sbjct: 74 EIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKP--YSGRRPDA-IRLGLGNH 130
Query: 529 NYCRNPDGDVGGPWCYTTNPRKL-YDYCDVPQCAAPSFDC 567
NYCRNPD D PWCY K ++C P C+ + DC
Sbjct: 131 NYCRNPDRD-SKPWCYVFKAGKYSSEFCSTPACSEGNSDC 169
>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
Length = 290
Score = 233 bits (595), Expect = 4e-61
Identities = 105/233 (45%), Positives = 148/233 (63%), Gaps = 8/233 (3%)
Query: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
Query: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH F P+++ + L+ENYC
Sbjct: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177
Query: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 178 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 237
Query: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTT 264
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T
Sbjct: 238 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
Score = 189 bits (481), Expect = 7e-48
Identities = 80/171 (46%), Positives = 109/171 (63%), Gaps = 9/171 (5%)
Query: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
C+ G +Y G +S T SG++CQ W S PH H ++PS + K+L++NYCRNP E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 188 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 239
Query: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDS 354
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C++
Sbjct: 240 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
Score = 184 bits (466), Expect = 4e-46
Identities = 81/181 (44%), Positives = 103/181 (56%), Gaps = 21/181 (11%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRA-P 333
C+ G G +Y+G V++T SG CQ WS+ PH H+ P ++ K+L ENYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 334 WCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT 393
WC T+N +VR+E C IP C +C +G+SYRG T
Sbjct: 188 WCFTSNPEVRYEVCDIPQCSEV--------------------ECMTCNGESYRGLMDHTE 227
Query: 394 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453
+GK CQ W TPHRH+ PE YP+ G NYCRNPD PWC+T DP RWEYC +K
Sbjct: 228 SGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKT 287
Query: 454 C 454
C
Sbjct: 288 C 288
Score = 170 bits (431), Expect = 4e-42
Identities = 82/188 (43%), Positives = 105/188 (55%), Gaps = 25/188 (13%)
Query: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433
+++C G G+SY+GT S T +G KCQ WSSM PH H P +Y L NYCRNP ++
Sbjct: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
Query: 434 -GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGK 492
GPWCFT++P VR+E C++ +C SE +CM NG+ YRG
Sbjct: 185 GGPWCFTSNPEVRYEVCDIPQC----------------------SEVECMTCNGESYRGL 222
Query: 493 RATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLY 552
T +G CQ W Q PHRH F PE P G + NYCRNPDG PWCYT +P +
Sbjct: 223 MDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQ-PRPWCYTLDPHTRW 280
Query: 553 DYCDVPQC 560
+YC + C
Sbjct: 281 EYCAIKTC 288
Score = 102 bits (255), Expect = 1e-21
Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 16/129 (12%)
Query: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
+C+ G G+ Y+G + T +G CQ W++ PH HS F P + L++NYCRNP G+ G
Sbjct: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEEG 185
Query: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 186 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 236
Query: 594 WQVSLRTRF 602
Q R +F
Sbjct: 237 HQTPHRHKF 245
>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
Length = 285
Score = 223 bits (568), Expect = 6e-58
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 13/233 (5%)
Query: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
Query: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH + + L+ENYC
Sbjct: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENYC 172
Query: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 173 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 232
Query: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTT 264
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T
Sbjct: 233 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
Score = 179 bits (453), Expect = 1e-44
Identities = 79/171 (46%), Positives = 105/171 (61%), Gaps = 14/171 (8%)
Query: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
C+ G +Y G +S T SG++CQ W S PH H Y K+L++NYCRNP E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSY-----RGKDLQENYCRNPRGEEGGP 182
Query: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 183 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 234
Query: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDS 354
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C++
Sbjct: 235 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
Score = 176 bits (446), Expect = 8e-44
Identities = 80/181 (44%), Positives = 101/181 (55%), Gaps = 26/181 (14%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRA-P 333
C+ G G +Y+G V++T SG CQ WS+ PH H+ + K+L ENYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEEGGP 182
Query: 334 WCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT 393
WC T+N +VR+E C IP C +C +G+SYRG T
Sbjct: 183 WCFTSNPEVRYEVCDIPQCSEV--------------------ECMTCNGESYRGLMDHTE 222
Query: 394 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453
+GK CQ W TPHRH+ PE YP+ G NYCRNPD PWC+T DP RWEYC +K
Sbjct: 223 SGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKT 282
Query: 454 C 454
C
Sbjct: 283 C 283
Score = 163 bits (412), Expect = 7e-40
Identities = 81/188 (43%), Positives = 104/188 (55%), Gaps = 30/188 (15%)
Query: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433
+++C G G+SY+GT S T +G KCQ WSSM PH H +Y L NYCRNP ++
Sbjct: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEE 179
Query: 434 -GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGK 492
GPWCFT++P VR+E C++ +C SE +CM NG+ YRG
Sbjct: 180 GGPWCFTSNPEVRYEVCDIPQC----------------------SEVECMTCNGESYRGL 217
Query: 493 RATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLY 552
T +G CQ W Q PHRH F PE P G + NYCRNPDG PWCYT +P +
Sbjct: 218 MDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQ-PRPWCYTLDPHTRW 275
Query: 553 DYCDVPQC 560
+YC + C
Sbjct: 276 EYCAIKTC 283
Score = 97.1 bits (240), Expect = 6e-20
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
+C+ G G+ Y+G + T +G CQ W++ PH HS + L++NYCRNP G+ G
Sbjct: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKD------LQENYCRNPRGEEG 180
Query: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 231
Query: 594 WQVSLRTRF 602
Q R +F
Sbjct: 232 HQTPHRHKF 240
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 211 bits (537), Expect = 2e-54
Identities = 131/373 (35%), Positives = 189/373 (50%), Gaps = 50/373 (13%)
Query: 479 EDCMFGNGKGYRGKRATTVTGTPCQDWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDG 536
+DC G+G YRGK TV C W + +++F + E N+CRNPD
Sbjct: 192 DDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDA 251
Query: 537 DVGGPWCY--TTNPRKLYDYCDVPQCAA-----------------PSFD-CGKPQVEPKK 576
D PWC+ TN + ++YCDV C+A P FD CGK ++ +K
Sbjct: 252 DEK-PWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERK 310
Query: 577 CPGRVVGGCVAHPHSWPWQVSLRTRFGM-------HFCGGTLISPEWVLTAAHCLEKSPR 629
R+ GG + PWQ SL++ + HFCGG LI P WVLTAAHC + R
Sbjct: 311 IK-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTR 369
Query: 630 PSSYKVILGAHQEVNLEPHVQEIEVSRLFL--------EPTRKDIALLKLSSP----AVI 677
KV+LG E H Q V ++F E DIALLKL A+
Sbjct: 370 --HLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALE 427
Query: 678 TDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNG 737
+ V CLP ++ +EC I+GWG T+ G+ L +A++ +I N +CN + +
Sbjct: 428 SKYVKTVCLPDGSF--PSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDH 485
Query: 738 RVQSTELCAGHLAG-GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRV 796
+ + +CAG+L G D+CQGDSGGPL C + Y + G+ SWGL C + +PGVY +V
Sbjct: 486 MIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RPGVYTQV 543
Query: 797 SRFVTWIEGVMRN 809
++F+ WI+ +++
Sbjct: 544 TKFLNWIKATIKS 556
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 7/111 (6%)
Query: 376 DCYHGDGQSYRGTSSTTTTGKKCQSWSS--MTPHRHQKTPENYPNAGL-TMNYCRNPDAD 432
DCY GDG SYRG + T C W+S + + E+ G+ N+CRNPDAD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 433 KGPWCF--TTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDC 481
+ PWCF T+ V+WEYC++ CS + + P P + P + C
Sbjct: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTE--PSTKLPGFDSC 301
Score = 78.6 bits (192), Expect = 2e-14
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQT--PHTHNRTPENFPCKNLDE-NYCRNPDGKR 331
C G G +YRG + TV+ H C +W++ +N E+ + E N+CRNPD
Sbjct: 194 CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADE 253
Query: 332 APWCH--TTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDC 377
PWC TN +V+WEYC + +C + V+ + +PT P P C
Sbjct: 254 KPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSC 301
Score = 60.8 bits (146), Expect = 5e-09
Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 6/88 (6%)
Query: 102 ECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSE--GL-EENYCRNPDND 158
+C G+G +YRG M++T N C W+S + ++ +E G+ E N+CRNPD D
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 159 PQGPWCY--TTDPEKRYDYCDILECEEE 184
+ PWC+ T+ + +++YCD+ C +
Sbjct: 253 -EKPWCFIKVTNDKVKWEYCDVSACSAQ 279
Score = 58.5 bits (140), Expect = 2e-08
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 10/123 (8%)
Query: 175 YCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQ---SPHAHGYIPSKFPNKNLKK 231
+C+I ++C G +Y GK+++T++ C W+S + + ++ + +
Sbjct: 186 FCEI--GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEH 243
Query: 232 NYCRNPDRELRPWCF--TTDPNKRWELCDIPRCTTPP---PSSGPTYQCLKGTGENYRGN 286
N+CRNPD + +PWCF T+ +WE CD+ C+ P PT K G + G
Sbjct: 244 NFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGK 303
Query: 287 VAV 289
+
Sbjct: 304 TEI 306
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 208 bits (530), Expect = 1e-53
Identities = 165/575 (28%), Positives = 238/575 (41%), Gaps = 86/575 (14%)
Query: 300 SAQTPHTHNRTPENFPCK------NLDENYCRNPDGKRAPWCHTTNSQVR---WEYCKIP 350
S+ +P T + PC+ + C + WC TT++ R W YC
Sbjct: 92 SSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYC--- 148
Query: 351 SCDSSPVSTEQLAPTAPPELTPVVQD-CYHG-------DGQSYRGTSSTTTTGKKCQSWS 402
+++P P P L P C +G D QSY + TGK C +
Sbjct: 149 -VEATP------PPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEK 201
Query: 403 SMTPHRHQKTPENYPNAGLTMNYCRNPDADKG-PWCFTT-------DPSVRWEYCNLKKC 454
R++ A + + + G WC T P + C+L
Sbjct: 202 CFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLIVA 261
Query: 455 SGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAA----QEP 510
+GT P L ++E +E C GNG GYRG +T+ +G C W + QE
Sbjct: 262 TGTTVCACPPGFAGRLCNIEP--DERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQEL 319
Query: 511 HRHSIFTPETNPRAGLEKN-YCRNPDGDVGGPWCYTTNPRKL-YDYCDVPQC-------- 560
H S+ GL + YCRNPD D PWCY L ++YC + C
Sbjct: 320 HVDSVGAAAL---LGLGPHAYCRNPDNDER-PWCYVVKDSALSWEYCRLEACESLTRVQL 375
Query: 561 -----------AAPSFD-CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCG 608
A+P CG+ + R++GG + P S PW ++ G FC
Sbjct: 376 SPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGDSFCA 433
Query: 609 GTLISPEWVLTAAHCLEKSPRPSSYKVILGAH---------QEVNLEPHVQEIEVSRLFL 659
G+L+ WV++AAHC SP S V+LG H Q +E ++ S
Sbjct: 434 GSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYS--VF 491
Query: 660 EPTRKDIALLKLSSP----AVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG--A 713
P+ D+ L++L A + V P CLP P +C I GWG +
Sbjct: 492 NPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYS 551
Query: 714 GLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYI 773
L+EA +P++ + C+ E + LCAG+ +D+CQGDSGGPL C +
Sbjct: 552 SSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAY 611
Query: 774 LQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMR 808
L G+ SWG GC R +KPGVY RV+ +V WI +R
Sbjct: 612 LYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646
Score = 67.4 bits (163), Expect = 5e-11
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 16/130 (12%)
Query: 262 CTTPPPSSG------PTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFP 315
C PP +G P +C G G YRG + + SG +C W++ +
Sbjct: 267 CACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGA 326
Query: 316 CKNL---DENYCRNPDGKRAPWCHTT-NSQVRWEYCKIPSCDSSPVSTEQLAP----TAP 367
L YCRNPD PWC+ +S + WEYC++ +C+S ++ QL+P T P
Sbjct: 327 AALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACES--LTRVQLSPDLLATLP 384
Query: 368 PELTPVVQDC 377
+P Q C
Sbjct: 385 EPASPGRQAC 394
Score = 58.2 bits (139), Expect = 3e-08
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 179 LECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKN---YCR 235
+E +E C +G Y G S + SGL C AW+S + ++ S L YCR
Sbjct: 280 IEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCR 339
Query: 236 NPDRELRPWCFTT-DPNKRWELCDIPRC 262
NPD + RPWC+ D WE C + C
Sbjct: 340 NPDNDERPWCYVVKDSALSWEYCRLEAC 367
Score = 57.8 bits (138), Expect = 4e-08
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGL---EENYCRNPDNDP 159
C GNG YRG S + +G++C W+S ++ + + L YCRNPDND
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDND- 344
Query: 160 QGPWCYTT-DPEKRYDYCDILECE 182
+ PWCY D ++YC + CE
Sbjct: 345 ERPWCYVVKDSALSWEYCRLEACE 368
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 197 bits (500), Expect = 4e-50
Identities = 125/330 (37%), Positives = 173/330 (52%), Gaps = 37/330 (11%)
Query: 497 VTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCD 556
V G C++ HS T G +C + G +T ++ CD
Sbjct: 85 VAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDE-----GRLPHTQRLLEVISVCD 139
Query: 557 VPQ---CAAPSFDCGKPQVEPKKCP-GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLI 612
P+ AA DCG+ +K P R+VGG WPWQVSLR G H CGG+L+
Sbjct: 140 CPRGRFLAAICQDCGR-----RKLPVDRIVGGRDTSLGRWPWQVSLRYD-GAHLCGGSLL 193
Query: 613 SPEWVLTAAHCLEKSPRP-SSYKVILGAHQEVNLEPHVQEIEVSRL--------FLEPTR 663
S +WVLTAAHC + R S ++V GA + + PH ++ V + F +P
Sbjct: 194 SGDWVLTAAHCFPERNRVLSRWRVFAGAVAQAS--PHGLQLGVQAVVYHGGYLPFRDPNS 251
Query: 664 K----DIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG--AGLLK 717
+ DIAL+ LSSP +T+ + P CLP+ + D C +TGWG TQ +G AG+L+
Sbjct: 252 EENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQ 310
Query: 718 EAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEK----DKYI 773
EA++P+I N VCN +F +++ CAG+ GG D+CQGDSGGP VC + ++
Sbjct: 311 EARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWR 370
Query: 774 LQGVTSWGLGCARPNKPGVYVRVSRFVTWI 803
L G+ SWG GCA KPGVY +VS F WI
Sbjct: 371 LCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 197 bits (500), Expect = 4e-50
Identities = 125/330 (37%), Positives = 173/330 (52%), Gaps = 37/330 (11%)
Query: 497 VTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCD 556
V G C++ HS T G +C + G +T ++ CD
Sbjct: 85 VAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDE-----GRLPHTQRLLEVISVCD 139
Query: 557 VPQ---CAAPSFDCGKPQVEPKKCP-GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLI 612
P+ AA DCG+ +K P R+VGG WPWQVSLR G H CGG+L+
Sbjct: 140 CPRGRFLAAICQDCGR-----RKLPVDRIVGGRDTSLGRWPWQVSLRYD-GAHLCGGSLL 193
Query: 613 SPEWVLTAAHCLEKSPRP-SSYKVILGAHQEVNLEPHVQEIEVSRL--------FLEPTR 663
S +WVLTAAHC + R S ++V GA + + PH ++ V + F +P
Sbjct: 194 SGDWVLTAAHCFPERNRVLSRWRVFAGAVAQAS--PHGLQLGVQAVVYHGGYLPFRDPNS 251
Query: 664 K----DIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG--AGLLK 717
+ DIAL+ LSSP +T+ + P CLP+ + D C +TGWG TQ +G AG+L+
Sbjct: 252 EENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQ 310
Query: 718 EAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEK----DKYI 773
EA++P+I N VCN +F +++ CAG+ GG D+CQGDSGGP VC + ++
Sbjct: 311 EARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWR 370
Query: 774 LQGVTSWGLGCARPNKPGVYVRVSRFVTWI 803
L G+ SWG GCA KPGVY +VS F WI
Sbjct: 371 LCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 192 bits (489), Expect = 8e-49
Identities = 99/237 (41%), Positives = 141/237 (59%), Gaps = 7/237 (2%)
Query: 580 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 639
R+VGG ++ WPWQ SL+ + G H CGG++I+P W++TAAHC+ P S+ + +G
Sbjct: 216 RIVGGNMSLLSQWPWQASLQFQ-GYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGL 274
Query: 640 HQEVN--LEPHVQEIEVSRLFLEPTR--KDIALLKLSSPAVITDKVIPACLPSPNYVVAD 695
++ H+ E V +P R DIAL+KL+ P + + P CLP+ D
Sbjct: 275 VSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPD 334
Query: 696 RTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGT 753
C+ +GWG T+ G + +L A +P+I NK+CN + G + + LCAG+L GG
Sbjct: 335 GKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGV 394
Query: 754 DSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810
DSCQGDSGGPLVC E+ + L G TS+G+GCA NKPGVY RV+ F+ WI M +
Sbjct: 395 DSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERD 451
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 191 bits (485), Expect = 2e-48
Identities = 101/269 (37%), Positives = 148/269 (55%), Gaps = 22/269 (8%)
Query: 555 CDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISP 614
C Q A + CG+P++ R+VGG WPWQVS++ R G HFCGG+LI+
Sbjct: 14 CFGSQRAKAATACGRPRML-----NRMVGGQDTQEGEWPWQVSIQ-RNGSHFCGGSLIAE 67
Query: 615 EWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIAL 668
+WVLTAAHC + S Y+V+LGA Q V PH V ++ P + D+AL
Sbjct: 68 QWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVAL 127
Query: 669 LKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWG---ETQGTFGAGLLKEAQLPVIE 725
++L +P T+ ++P CLP P+ + C++TGWG E +L++ +P+I+
Sbjct: 128 VELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIID 187
Query: 726 NKVCN-------RYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVT 778
CN + + +++ LCAG G D+C+GDSGGPLVC ++ GV
Sbjct: 188 TPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVI 247
Query: 779 SWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
SWG GCAR N+PGVY+RV+ WI ++
Sbjct: 248 SWGEGCARQNRPGVYIRVTAHHNWIHRII 276
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 190 bits (482), Expect = 5e-48
Identities = 107/249 (42%), Positives = 141/249 (56%), Gaps = 21/249 (8%)
Query: 567 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK 626
CG+PQV GR+VGG A +WPWQ SLR R +H CGG+L+SP+WVLTAAHC
Sbjct: 26 CGRPQVSD--AGGRIVGGHAAPAGAWPWQASLRLR-RVHVCGGSLLSPQWVLTAAHCFSG 82
Query: 627 SPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP-----TRKDIALLKLSSPAVITDKV 681
S S Y+V LG E+ L PH + L P T DIAL++LS P ++ ++
Sbjct: 83 SLNSSDYQVHLG-ELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRI 141
Query: 682 IPACLPSPNYVVADRTECFITGWGETQGTFGAGL-----LKEAQLPVIENKVCNR-YEFL 735
+P CLP + C++TGWG T+ G L L+E ++ V++ + C R Y
Sbjct: 142 LPVCLPEASDDFCPGIRCWVTGWGYTRE--GEPLPPPYSLREVKVSVVDTETCRRDYPGP 199
Query: 736 NGRV-QSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYV 794
G + Q LCA G D+CQ DSGGPLVC ++ G+ SWG GC RPN+PGVY
Sbjct: 200 GGSILQPDMLCA---RGPGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYT 256
Query: 795 RVSRFVTWI 803
RV +V WI
Sbjct: 257 RVPAYVNWI 265
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 189 bits (480), Expect = 9e-48
Identities = 100/256 (39%), Positives = 142/256 (55%), Gaps = 26/256 (10%)
Query: 567 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK 626
CG+P++ R+VGG WPWQ S++ R G H CGG+LI+P+WVLTAAHC +
Sbjct: 28 CGQPRMS-----SRIVGGRDGRDGEWPWQASIQHR-GAHVCGGSLIAPQWVLTAAHCFPR 81
Query: 627 SPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDK 680
P+ Y+V LGA + + P + V R+ L P R D+ALL+L P ++ +
Sbjct: 82 RALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSAR 141
Query: 681 VIPACLPSPNYVVADRTECFITGWGETQGTFGAGL-----LKEAQLPVIENKVCNRYEFL 735
V P CLP P T C +TGWG + G L L+ ++P+++++ C+ +
Sbjct: 142 VQPVCLPVPGARPPPGTPCRVTGWGSLRP--GVPLPEWRPLQGVRVPLLDSRTCDGLYHV 199
Query: 736 NGRVQSTE-------LCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPN 788
V E LCAG+ G D+CQGDSGGPL C + ++L GV SWG GCA PN
Sbjct: 200 GADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPN 259
Query: 789 KPGVYVRVSRFVTWIE 804
+PGVY V+ + WI+
Sbjct: 260 RPGVYTSVATYSPWIQ 275
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 185 bits (470), Expect = 1e-46
Identities = 103/239 (43%), Positives = 137/239 (57%), Gaps = 10/239 (4%)
Query: 579 GRVVGGCVAHPHSWPWQVSLRTRFGM-HFCGGTLISPEWVLTAAHC--LEKSPRPSSYKV 635
GR+VGG +A WPWQVSL FG H CGGTLI +WVLTAAHC + + +KV
Sbjct: 324 GRIVGGALASDSKWPWQVSLH--FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKV 381
Query: 636 ILGA---HQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYV 692
G HQ + I S E DIAL++LS P ++ + PACLP
Sbjct: 382 YAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQT 441
Query: 693 VADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLA 750
+ C+ITG+G+T+ T + L+E Q+ +I+ K CN Y + + +CAG L
Sbjct: 442 FSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLR 501
Query: 751 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRN 809
GG DSCQGDSGGPLVC + +++ L GVTSWG GC + NKPGVY +V+ + WI M +
Sbjct: 502 GGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560
>gi|74048573 plasminogen-like B1 [Homo sapiens]
Length = 96
Score = 185 bits (469), Expect = 2e-46
Identities = 92/96 (95%), Positives = 93/96 (96%)
Query: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT 60
MEHKEVVLLLLLFLKSGQGEPLDDYVNTQG SLFSVTKKQLGAGS EECAAKCEED+EFT
Sbjct: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGPSLFSVTKKQLGAGSREECAAKCEEDKEFT 60
Query: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEK 96
CRAFQYHSKEQQCVIMAENRKSSIIIRMRD VLFEK
Sbjct: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDAVLFEK 96
>gi|4505883 plasminogen-like B2 [Homo sapiens]
Length = 96
Score = 185 bits (469), Expect = 2e-46
Identities = 92/96 (95%), Positives = 93/96 (96%)
Query: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT 60
MEHKEVVLLLLLFLKSGQGEPLDDYVNTQG SLFSVTKKQLGAGS EECAAKCEED+EFT
Sbjct: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGPSLFSVTKKQLGAGSREECAAKCEEDKEFT 60
Query: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEK 96
CRAFQYHSKEQQCVIMAENRKSSIIIRMRD VLFEK
Sbjct: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDAVLFEK 96
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 181 bits (458), Expect = 3e-45
Identities = 127/361 (35%), Positives = 170/361 (47%), Gaps = 35/361 (9%)
Query: 474 ETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNP-RAGLEK-NYC 531
E + C GNG YRGK +T G PC W + + + ++ + GL K NYC
Sbjct: 46 EIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYC 105
Query: 532 RNPDGDVGGPWCYT-TNPRKLYDYCDVPQCA---APS-------FDCGKPQVEPKKCPGR 580
RNPD PWCY + L C V CA PS F CG+ + P+ +
Sbjct: 106 RNPDNR-RRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRF---K 161
Query: 581 VVGGCVAHPHSWPWQVSL--RTRFGM--HFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 636
++GG + PW ++ R R G + CGG+LISP WV++A HC P+ Y V
Sbjct: 162 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVY 221
Query: 637 LGAHQEVNLEPHVQEIEVSRLFLEPT--------RKDIALLKLSSP----AVITDKVIPA 684
LG + + + EV L L DIALLK+ S A + +
Sbjct: 222 LGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTI 281
Query: 685 CLPSPNYVVADRTECFITGWGETQGT--FGAGLLKEAQLPVIENKVCNRYEFLNGRVQST 742
CLPS T C ITG+G+ T LK + +I ++ C + + V +
Sbjct: 282 CLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTK 341
Query: 743 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTW 802
LCA TDSCQGDSGGPLVC + + L G+ SWG GCA +KPGVY RVS F+ W
Sbjct: 342 MLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPW 401
Query: 803 I 803
I
Sbjct: 402 I 402
Score = 57.8 bits (138), Expect = 4e-08
Identities = 28/67 (41%), Positives = 38/67 (56%), Gaps = 7/67 (10%)
Query: 377 CYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM-----NYCRNPDA 431
CY G+G YRG +ST T G+ C W+S T Q+T + + L + NYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATV--LQQTYHAHRSDALQLGLGKHNYCRNPDN 110
Query: 432 DKGPWCF 438
+ PWC+
Sbjct: 111 RRRPWCY 117
Score = 53.9 bits (128), Expect = 6e-07
Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 14/101 (13%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWSA-----QTPHTHNRTPENFPCKNLDENYCRNPDG 329
C +G G YRG + G C W++ QT H H NYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGK--HNYCRNPDN 110
Query: 330 KRAPWCHT-TNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPE 369
+R PWC+ + + C + C + P++PPE
Sbjct: 111 RRRPWCYVQVGLKPLVQECMVHDC------ADGKKPSSPPE 145
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 8/68 (11%)
Query: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLE-----ENYCRNPDN 157
C GNG YRG S G C W+S + + + H S+ L+ NYCRNPDN
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYH--AHRSDALQLGLGKHNYCRNPDN 110
Query: 158 DPQGPWCY 165
+ PWCY
Sbjct: 111 -RRRPWCY 117
Score = 48.9 bits (115), Expect = 2e-05
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
Query: 175 YCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNL---KK 231
+C+I + + C +G Y GK S G C W+S + Y + L K
Sbjct: 44 HCEI-DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKH 102
Query: 232 NYCRNPDRELRPWCF 246
NYCRNPD RPWC+
Sbjct: 103 NYCRNPDNRRRPWCY 117
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 181 bits (458), Expect = 3e-45
Identities = 127/361 (35%), Positives = 170/361 (47%), Gaps = 35/361 (9%)
Query: 474 ETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNP-RAGLEK-NYC 531
E + C GNG YRGK +T G PC W + + + ++ + GL K NYC
Sbjct: 63 EIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYC 122
Query: 532 RNPDGDVGGPWCYT-TNPRKLYDYCDVPQCA---APS-------FDCGKPQVEPKKCPGR 580
RNPD PWCY + L C V CA PS F CG+ + P+ +
Sbjct: 123 RNPDNR-RRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRF---K 178
Query: 581 VVGGCVAHPHSWPWQVSL--RTRFGM--HFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 636
++GG + PW ++ R R G + CGG+LISP WV++A HC P+ Y V
Sbjct: 179 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVY 238
Query: 637 LGAHQEVNLEPHVQEIEVSRLFLEPT--------RKDIALLKLSSP----AVITDKVIPA 684
LG + + + EV L L DIALLK+ S A + +
Sbjct: 239 LGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTI 298
Query: 685 CLPSPNYVVADRTECFITGWGETQGT--FGAGLLKEAQLPVIENKVCNRYEFLNGRVQST 742
CLPS T C ITG+G+ T LK + +I ++ C + + V +
Sbjct: 299 CLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTK 358
Query: 743 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTW 802
LCA TDSCQGDSGGPLVC + + L G+ SWG GCA +KPGVY RVS F+ W
Sbjct: 359 MLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPW 418
Query: 803 I 803
I
Sbjct: 419 I 419
Score = 57.8 bits (138), Expect = 4e-08
Identities = 28/67 (41%), Positives = 38/67 (56%), Gaps = 7/67 (10%)
Query: 377 CYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM-----NYCRNPDA 431
CY G+G YRG +ST T G+ C W+S T Q+T + + L + NYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATV--LQQTYHAHRSDALQLGLGKHNYCRNPDN 127
Query: 432 DKGPWCF 438
+ PWC+
Sbjct: 128 RRRPWCY 134
Score = 53.9 bits (128), Expect = 6e-07
Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 14/101 (13%)
Query: 275 CLKGTGENYRGNVAVTVSGHTCQHWSA-----QTPHTHNRTPENFPCKNLDENYCRNPDG 329
C +G G YRG + G C W++ QT H H NYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGK--HNYCRNPDN 127
Query: 330 KRAPWCHT-TNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPE 369
+R PWC+ + + C + C + P++PPE
Sbjct: 128 RRRPWCYVQVGLKPLVQECMVHDC------ADGKKPSSPPE 162
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 8/68 (11%)
Query: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLE-----ENYCRNPDN 157
C GNG YRG S G C W+S + + + H S+ L+ NYCRNPDN
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYH--AHRSDALQLGLGKHNYCRNPDN 127
Query: 158 DPQGPWCY 165
+ PWCY
Sbjct: 128 -RRRPWCY 134
Score = 48.9 bits (115), Expect = 2e-05
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
Query: 175 YCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNL---KK 231
+C+I + + C +G Y GK S G C W+S + Y + L K
Sbjct: 61 HCEI-DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKH 119
Query: 232 NYCRNPDRELRPWCF 246
NYCRNPD RPWC+
Sbjct: 120 NYCRNPDNRRRPWCY 134
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 180 bits (456), Expect = 5e-45
Identities = 98/266 (36%), Positives = 143/266 (53%), Gaps = 20/266 (7%)
Query: 563 PSFDCGKPQVEPKKCP--------GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISP 614
P +C QV +C R+VGG P WPWQ S+ F H CGG++++P
Sbjct: 192 PRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGF-RHTCGGSVLAP 250
Query: 615 EWVLTAAHCLE--KSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRK------DI 666
WV+TAAHC+ + R SS++V G + PH Q V R+ P D+
Sbjct: 251 RWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPH-QGALVERIIPHPLYSAQNHDYDV 309
Query: 667 ALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQG--TFGAGLLKEAQLPVI 724
ALL+L + +D V CLP+ + C+++GWG T T+ + +L++ +P+
Sbjct: 310 ALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLF 369
Query: 725 ENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGC 784
++CN +G + LCAG+L G D+CQGDSGGPLVC + D + L GV SWG GC
Sbjct: 370 STQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGC 429
Query: 785 ARPNKPGVYVRVSRFVTWIEGVMRNN 810
A PN PGVY +V+ F+ WI +++
Sbjct: 430 AEPNHPGVYAKVAEFLDWIHDTAQDS 455
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 180 bits (456), Expect = 5e-45
Identities = 100/250 (40%), Positives = 135/250 (54%), Gaps = 14/250 (5%)
Query: 567 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK 626
CG P P+ R+ GG A PH WPWQV LR G + CGG +I+P W+LTAAHC++
Sbjct: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRF-LGDYQCGGAIINPVWILTAAHCVQL 619
Query: 627 SPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTR-------KDIALLKLSSPAVITD 679
P S+ +I G H NL+ +++ ++ + DIAL++LSSP
Sbjct: 620 KNNPLSWTIIAGDHDR-NLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNS 678
Query: 680 KVIPACLPSPNYVVADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKVCNR--YEFLN 736
V P CLP + C +TGWG G A L++ Q+ V+E +VC Y
Sbjct: 679 VVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHP 738
Query: 737 GRVQSTELCAGHLAGGT-DSCQGDSGGPLVC-FEKDKYILQGVTSWGLGCARPNKPGVYV 794
G + +CAG A G D CQGDSGGPLVC E ++L G+ SWG GC +P KPGV+
Sbjct: 739 GGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFA 798
Query: 795 RVSRFVTWIE 804
RV F+ WI+
Sbjct: 799 RVMIFLDWIQ 808
Score = 121 bits (304), Expect = 2e-27
Identities = 85/237 (35%), Positives = 121/237 (51%), Gaps = 30/237 (12%)
Query: 593 PWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK--SPRPSSYKVILGAHQEVNLEPHVQ 650
PWQVSL++ HFCGG+LI + V+TAAHCL+ + + V G + + Q
Sbjct: 59 PWQVSLKSD-EHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQ 117
Query: 651 EIEVSRLFLEPTRK-------DIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITG 703
I VS++ P DIALL L + V P CLP + V C +G
Sbjct: 118 NIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSG 177
Query: 704 WGETQGTFG-AGLLKEAQLPVIENKVCNRY-EFLN----GRVQSTELCAGHLAGGTDSCQ 757
WG+ T + +L+E +LP+++++ CN + +N GR T LCAG G D+CQ
Sbjct: 178 WGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGR---TMLCAGFPDWGMDACQ 234
Query: 758 GDSGGPLVCFEKDK-YILQGVTSWGLGCARPNKP----------GVYVRVSRFVTWI 803
GDSGGPLVC +IL G+TSW GCA + P G++ +VS + +I
Sbjct: 235 GDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 179 bits (454), Expect = 9e-45
Identities = 100/256 (39%), Positives = 136/256 (53%), Gaps = 16/256 (6%)
Query: 564 SFDCGKPQVEPK-KCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAH 622
S+ CG P ++P R+V G A SWPWQVSL+ G HFCGG+LIS WV+TAAH
Sbjct: 16 SWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAH 75
Query: 623 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAV 676
C + P + V+LG + + +Q + VSR P+ D+ LLKL+SPA
Sbjct: 76 C---NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQ 132
Query: 677 ITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGA--GLLKEAQLPVIENKVCNRYEF 734
T ++ P CL S N + + C TGWG G L++ LP++ C +Y
Sbjct: 133 YTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQY-- 190
Query: 735 LNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYV 794
+ + +CAG G SCQGDSGGPLVC + + ++L G+ SWG P VY
Sbjct: 191 WGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYT 248
Query: 795 RVSRFVTWIEGVMRNN 810
RVS+F TWI V+ N
Sbjct: 249 RVSKFSTWINQVIAYN 264
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 177 bits (448), Expect = 5e-44
Identities = 110/284 (38%), Positives = 152/284 (53%), Gaps = 20/284 (7%)
Query: 534 PDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWP 593
PDG + T + + L D QC S CGK P ++VGG A +WP
Sbjct: 745 PDGHL----ILTPSQQCLQDSLIRLQCNHKS--CGKKLAAQDITP-KIVGGSNAKEGAWP 797
Query: 594 WQVSLRTRFGMHFCGGTLISPEWVLTAAHCLE-KSPRPSSYKVILGAHQEVNL-EPHVQE 651
W V L G CG +L+S +W+++AAHC+ ++ PS + ILG H + NL P
Sbjct: 798 WVVGLYYG-GRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVP 856
Query: 652 IEVSRLFLEP----TRKD--IALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWG 705
+ + + P RKD IA++ L TD + P CLP N V C I GWG
Sbjct: 857 RLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWG 916
Query: 706 ET--QGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGP 763
QGT A +L+EA +P++ N+ C + + + +CAG+ GG DSCQGDSGGP
Sbjct: 917 TVVYQGTT-ANILQEADVPLLSNERCQQ-QMPEYNITENMICAGYEEGGIDSCQGDSGGP 974
Query: 764 LVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
L+C E +++ L GVTS+G CA PN+PGVY RVSRF WI+ +
Sbjct: 975 LMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFL 1018
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 177 bits (448), Expect = 5e-44
Identities = 89/251 (35%), Positives = 138/251 (54%), Gaps = 13/251 (5%)
Query: 566 DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVLTAAH 622
DCG ++ R++GG A +WPW VSL+ ++G +H CGGTL+ WVLTAAH
Sbjct: 63 DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAH 122
Query: 623 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAV 676
C + + P + ++G + PH ++I++ + + P DIAL L
Sbjct: 123 CTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVR 182
Query: 677 ITDKVIPACLPSPNYVVAD-RTECFITGWGETQGTFGA-GLLKEAQLPVIENKVCNRYEF 734
D + P CLP + + D T+CFI+GWG T+ A +L++A++ I ++CN
Sbjct: 183 YNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERS 242
Query: 735 LNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCF--EKDKYILQGVTSWGLGCARPNKPGV 792
G + +T CAG G D+C+GDSGGPL+C+ E ++ + G+TS+G GC R PGV
Sbjct: 243 YGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGV 302
Query: 793 YVRVSRFVTWI 803
Y+ S + W+
Sbjct: 303 YIGPSFYQKWL 313
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 176 bits (447), Expect = 6e-44
Identities = 97/256 (37%), Positives = 142/256 (55%), Gaps = 17/256 (6%)
Query: 564 SFDCGKPQVEPKKCP-GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAH 622
+F CG P + P R+V G A P SWPWQVSL+ + G HFCGG+LIS +WV+TAAH
Sbjct: 16 AFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAH 75
Query: 623 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAV 676
C + +S V+ G + + E ++Q ++++++F P DI LLKL++PA
Sbjct: 76 CGVR----TSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPAR 131
Query: 677 ITDKVIPACLPSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEF 734
+ V CLPS + T C TGWG+T+ L++A LP++ N C +
Sbjct: 132 FSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKK--S 189
Query: 735 LNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYV 794
R+ +CAG A G SC GDSGGPLVC + + L G+ SWG + PGVY
Sbjct: 190 WGRRITDVMICAG--ASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYA 247
Query: 795 RVSRFVTWIEGVMRNN 810
RV++ + W++ ++ N
Sbjct: 248 RVTKLIPWVQKILAAN 263
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 174 bits (442), Expect = 2e-43
Identities = 102/239 (42%), Positives = 129/239 (53%), Gaps = 16/239 (6%)
Query: 580 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCL-----EKSPRPSSYK 634
RVVGG A WPWQVSL H CG +LISP W+++AAHC + P+ +
Sbjct: 614 RVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWT 673
Query: 635 VILGAH-QEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLSSPAVITDKVIPACLP 687
LG H Q P VQE + R+ P DIALL+L PA + V P CLP
Sbjct: 674 AFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLP 733
Query: 688 SPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCA 746
++V ++TGWG TQ G GA +L++ ++ VI C L ++ +C
Sbjct: 734 DASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCE--NLLPQQITPRMMCV 791
Query: 747 GHLAGGTDSCQGDSGGPLVCFEKDKYILQ-GVTSWGLGCARPNKPGVYVRVSRFVTWIE 804
G L+GG DSCQGDSGGPL E D I Q GV SWG GCA+ NKPGVY R+ F WI+
Sbjct: 792 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIK 850
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,288,285
Number of Sequences: 37866
Number of extensions: 2226180
Number of successful extensions: 6126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 4773
Number of HSP's gapped (non-prelim): 383
length of query: 810
length of database: 18,247,518
effective HSP length: 110
effective length of query: 700
effective length of database: 14,082,258
effective search space: 9857580600
effective search space used: 9857580600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.