Search of human proteins with 4505219

Search of human proteins with 4505219

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505219 matrix metalloproteinase 7 preproprotein [Homo
sapiens]
         (267 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]    555   e-158
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...   257   8e-69
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]    249   2e-66
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]   247   9e-66
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]   243   2e-64
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...   238   3e-63
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...   236   2e-62
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]    236   2e-62
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                225   3e-59
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]      224   5e-59
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]   204   7e-53
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]   197   6e-51
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   195   4e-50
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...   195   4e-50
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      189   2e-48
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]   182   3e-46
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...   180   1e-45
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...   180   1e-45
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...   180   1e-45
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...   158   4e-39
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot...   147   1e-35
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...   144   6e-35
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]   141   5e-34
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ...   133   1e-31
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi...   108   5e-24
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]       89   5e-18
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]           68   1e-11
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]           66   4e-11
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]           66   4e-11
gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ...    64   1e-10

>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score =  555 bits (1431), Expect = e-158
 Identities = 267/267 (100%), Positives = 267/267 (100%)

Query: 1   MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK 60
           MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
Sbjct: 1   MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK 60

Query: 61  EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL 120
           EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
Sbjct: 61  EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL 120

Query: 121 PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF 180
           PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
Sbjct: 121 PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF 180

Query: 181 APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD 240
           APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
Sbjct: 181 APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD 240

Query: 241 PQNFKLSQDDIKGIQKLYGKRSNSRKK 267
           PQNFKLSQDDIKGIQKLYGKRSNSRKK
Sbjct: 241 PQNFKLSQDDIKGIQKLYGKRSNSRKK 267


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score =  257 bits (656), Expect = 8e-69
 Identities = 121/234 (51%), Positives = 154/234 (65%), Gaps = 8/234 (3%)

Query: 35  AQDYLKRFY-------LYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRC 87
           AQ YL ++Y       + +   + +NS+  K+KE+Q FFGL +TG L+   + +++KPRC
Sbjct: 41  AQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRC 100

Query: 88  GVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKV 147
           GVPDVA Y LFP  PKW    +TYRI  YT  +  + VD+ V  AL  W   +PL F ++
Sbjct: 101 GVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRI 160

Query: 148 VWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGIN 207
             G ADIMI F  G HGDSYPFDGP  TLAHAFAPG GLGGD HFD  E+WT G++ G N
Sbjct: 161 NSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN-GFN 219

Query: 208 FLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKR 261
               A HE GH+LG+ HS+DP+A+MYPTY   +P  F L +DD+KGIQ LYG R
Sbjct: 220 LFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPR 273


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score =  249 bits (635), Expect = 2e-66
 Identities = 131/269 (48%), Positives = 169/269 (62%), Gaps = 10/269 (3%)

Query: 3   LTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETK------NANSLE 56
           L +L  +C+   S A PL   A G  +      Q YL+ +Y    + K      ++  + 
Sbjct: 4   LPILLLLCVAVCS-AYPLDGAARG-EDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVV 61

Query: 57  AKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSY 116
            K++EMQKF GL +TG L+S  +E+M+KPRCGVPDV  +  FP  PKW    +TYRIV+Y
Sbjct: 62  KKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNY 121

Query: 117 TRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTL 176
           T DLP   VD  V KAL +W +  PL F ++  G ADIMI FA   HGD YPFDGPGN L
Sbjct: 122 TPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVL 181

Query: 177 AHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTY 236
           AHA+APG G+ GDAHFD+DE+WT  ++ G N    A HE+GHSLG+ HS++  A+MYP Y
Sbjct: 182 AHAYAPGPGINGDAHFDDDEQWTKDTT-GTNLFLVAAHEIGHSLGLFHSANTEALMYPLY 240

Query: 237 GN-GDPQNFKLSQDDIKGIQKLYGKRSNS 264
            +  D   F+LSQDDI GIQ LYG   +S
Sbjct: 241 HSLTDLTRFRLSQDDINGIQSLYGPPPDS 269


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score =  247 bits (630), Expect = 9e-66
 Identities = 128/265 (48%), Positives = 170/265 (64%), Gaps = 9/265 (3%)

Query: 1   MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETK-----NANSL 55
           M L  L  +CL P   A PL   A    +   + AQ YL+++Y  + + K     ++N +
Sbjct: 2   MHLAFLVLLCL-PVCSAYPL-SGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLI 59

Query: 56  EAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVS 115
             K++ MQKF GL +TG L++  +E+M+KPRCGVPDV  +S FP  PKW    +TYRIV+
Sbjct: 60  VKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVN 119

Query: 116 YTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNT 175
           YT DLP   VD  + KAL +W +  PL F ++  G ADIMI FA   HGD Y FDGPG++
Sbjct: 120 YTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHS 179

Query: 176 LAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPT 235
           LAHA+ PG GL GD HFD+DE+WT+ +S G N    A HELGHSLG+ HS++  A+MYP 
Sbjct: 180 LAHAYPPGPGLYGDIHFDDDEKWTEDAS-GTNLFLVAAHELGHSLGLFHSANTEALMYPL 238

Query: 236 YGN-GDPQNFKLSQDDIKGIQKLYG 259
           Y +  +   F+LSQDD+ GIQ LYG
Sbjct: 239 YNSFTELAQFRLSQDDVNGIQSLYG 263


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score =  243 bits (619), Expect = 2e-64
 Identities = 120/250 (48%), Positives = 158/250 (63%), Gaps = 8/250 (3%)

Query: 17  ALPLPQ--EAGGMSELQWEQAQDYLKRFYLYDS-----ETKNANSLEAKLKEMQKFFGLP 69
           ALPLP   +   +SE   + A+ YL+ +Y   +     +   A+S+  +L+EMQ FFGL 
Sbjct: 19  ALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLE 78

Query: 70  ITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLV 129
           +TG L+   +++M+KPRCGVPDV EY++FP + KW+   +TYRIV+YT D+ H  V++  
Sbjct: 79  VTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAF 138

Query: 130 SKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGD 189
            KA  +W    PL+F ++  G ADIMI F    HGD YPFDGP   LAHAF PG   GGD
Sbjct: 139 KKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGD 198

Query: 190 AHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQD 249
           AHFD+DE WT  SS G N    A HE GHSLG+ HS DP A+M+P Y      +F L  D
Sbjct: 199 AHFDDDETWT-SSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDD 257

Query: 250 DIKGIQKLYG 259
           D++GIQ LYG
Sbjct: 258 DVQGIQSLYG 267


>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score =  238 bits (608), Expect = 3e-63
 Identities = 118/236 (50%), Positives = 151/236 (63%), Gaps = 8/236 (3%)

Query: 38  YLKRFYLYDSE----TK---NANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVP 90
           YL++FY  +      TK   + N ++ K++EMQ F GL +TG L++  +E+M  PRCGVP
Sbjct: 36  YLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVP 95

Query: 91  DVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWG 150
           DV  +   P  P W    +TYRI +YT D+    VD  + KA  +W    PL F K+  G
Sbjct: 96  DVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTG 155

Query: 151 TADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLY 210
            ADI++ FARGAHGD + FDG G  LAHAF PG+G+GGDAHFDEDE WT  S  G N   
Sbjct: 156 MADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG-GTNLFL 214

Query: 211 AATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRK 266
            A HE+GHSLG+GHSSDP AVM+PTY   D   F+LS DDI+GIQ LYG    +++
Sbjct: 215 TAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKENQR 270


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score =  236 bits (602), Expect = 2e-62
 Identities = 118/235 (50%), Positives = 156/235 (66%), Gaps = 11/235 (4%)

Query: 36  QDYLKRFYLYDSE------TKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGV 89
           Q YL+++Y   ++       +N+  +  KLK+MQ+FFGL +TG  ++  +++M++PRCGV
Sbjct: 35  QKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGV 94

Query: 90  PDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVW 149
           PDVA++ L   +P+W    +TYRI +YT DLP   VD  + KA  +W    PL F KV  
Sbjct: 95  PDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSE 154

Query: 150 GTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFL 209
           G ADIMI F RG H D+ PFDGPG  LAHAF PG G+GGDAHFDEDERWT+ +    N  
Sbjct: 155 GQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTN-NFREYNLH 213

Query: 210 YAATHELGHSLGMGHSSDPNAVMYPTYG-NGDPQNFKLSQDDIKGIQKLYGKRSN 263
             A HELGHSLG+ HS+D  A+MYP+Y  +GD Q   L+QDDI GIQ +YG+  N
Sbjct: 214 RVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQ---LAQDDIDGIQAIYGRSQN 265


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score =  236 bits (601), Expect = 2e-62
 Identities = 118/241 (48%), Positives = 148/241 (61%), Gaps = 7/241 (2%)

Query: 29  ELQWEQAQDYLKRFYL-----YDSETKNA-NSLEAKLKEMQKFFGLPITGMLNSRVIEIM 82
           E   +  QDYL++FY      Y S  KN  N +  KLKEMQ+FFGL +TG  N   +++M
Sbjct: 27  EKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMM 86

Query: 83  QKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPL 142
           +KPRCGVPD   + L P +PKW    +TYRI +YT  L    V+R +  A  +W    PL
Sbjct: 87  KKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPL 146

Query: 143 HFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGS 202
            F ++  G ADI I F +  HGD+ PFDGP   LAHAF PG G+GGDAHFD +E WT+ +
Sbjct: 147 IFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTN-T 205

Query: 203 SLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRS 262
           S   N    A HE GHSLG+ HSSDP A+MYP Y   +  N+ L QDDI GIQ +YG  S
Sbjct: 206 SANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSS 265

Query: 263 N 263
           N
Sbjct: 266 N 266


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score =  225 bits (574), Expect = 3e-59
 Identities = 121/267 (45%), Positives = 158/267 (59%), Gaps = 14/267 (5%)

Query: 1   MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSE------TKNANS 54
           M+  +L  +  +  S A PL +       +Q  QA  YL +FY  + E      +KN + 
Sbjct: 1   MKRLLLLFLFFITFSSAFPLVRMTENEENMQLAQA--YLNQFYSLEIEGNHLVQSKNRSL 58

Query: 55  LEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIV 114
           ++ K++EMQ FFGL +TG L+S  +EIM+ PRCGVPDV +Y      P W    +TYRI+
Sbjct: 59  IDDKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGY--TLPGWRKYNLTYRII 116

Query: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYP-FDGPG 173
           +YT D+    VD  + + L +W K  PL F K+  G ADIMI F    HG     FDGP 
Sbjct: 117 NYTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPL 176

Query: 174 NTLAHAFAPGTGLGGDAHFDEDERWT-DGSSLGINFLYAATHELGHSLGMGHSSDPNAVM 232
             L HAF PG GLGGD HFDEDE WT DG+  G N    A HE GH+LG+ HS+D  A+M
Sbjct: 177 GVLGHAFPPGPGLGGDTHFDEDENWTKDGA--GFNLFLVAAHEFGHALGLSHSNDQTALM 234

Query: 233 YPTYGNGDPQNFKLSQDDIKGIQKLYG 259
           +P Y + DP+ + LSQDDI GIQ +YG
Sbjct: 235 FPNYVSLDPRKYPLSQDDINGIQSIYG 261


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score =  224 bits (572), Expect = 5e-59
 Identities = 110/203 (54%), Positives = 139/203 (68%), Gaps = 5/203 (2%)

Query: 62  MQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLP 121
           MQ+FFGL +TG  ++  +++M++PRCGVPDVA++ L   +P+W    +TYRI +YT DLP
Sbjct: 1   MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP 60

Query: 122 HITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFA 181
              VD  + KA  +W    PL F KV  G ADIMI F RG H D+ PFDGPG  LAHAF 
Sbjct: 61  RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ 120

Query: 182 PGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYG-NGD 240
           PG G+GGDAHFDEDERWT+ +    N    A HELGHSLG+ HS+D  A+MYP+Y  +GD
Sbjct: 121 PGPGIGGDAHFDEDERWTN-NFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGD 179

Query: 241 PQNFKLSQDDIKGIQKLYGKRSN 263
            Q   L+QDDI GIQ +YG+  N
Sbjct: 180 VQ---LAQDDIDGIQAIYGRSQN 199


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score =  204 bits (519), Expect = 7e-53
 Identities = 120/291 (41%), Positives = 168/291 (57%), Gaps = 34/291 (11%)

Query: 3   LTVLCAVCLLPGSLALPLPQEAGG------MSELQWEQA------QDYLKRF-YL--YDS 47
           L +L A+C LPG+          G      ++  + ++A      Q++LK + YL  YDS
Sbjct: 37  LLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAPFAGQNWLKSYGYLLPYDS 96

Query: 48  ETK---NANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSP-- 102
                 +A +L++ +  MQ+F+G+P+TG+L+   IE M+KPRCGVPD    S    +   
Sbjct: 97  RASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRY 156

Query: 103 -----KWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGT------ 151
                KW  K +TY I +YT  +  +   + + +A ++W K  PL F +V +        
Sbjct: 157 ALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRK 216

Query: 152 -ADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSL--GINF 208
            ADIMI FA G HGDS PFDG G  LAHA+ PG G+GGD HFD DE WT G++   G + 
Sbjct: 217 EADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDL 276

Query: 209 LYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYG 259
              A HELGH+LG+ HSSDP+A+M P Y   +  NFKL QDD++GIQK+YG
Sbjct: 277 FLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYG 327


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score =  197 bits (502), Expect = 6e-51
 Identities = 114/279 (40%), Positives = 155/279 (55%), Gaps = 21/279 (7%)

Query: 2   RLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKE 61
           R  +L  + +L G L L +  E   +    W +   YL +   + S  ++A  L + L E
Sbjct: 26  RPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAE 85

Query: 62  MQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPN-----------SPKWTSKVVT 110
           MQ+F+G+P+TG+L+    E M++PRCGVPD     +  N             KW +  +T
Sbjct: 86  MQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLT 145

Query: 111 YRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGT--------ADIMIGFARGA 162
           + I +YT  L        V +A  +W +  PL F++V +          ADIM+ FA G 
Sbjct: 146 FSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGF 205

Query: 163 HGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSS--LGINFLYAATHELGHSL 220
           HGDS PFDG G  LAHA+ PG GLGGD HFD DE WT  S+   G N    A HELGH+L
Sbjct: 206 HGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHAL 265

Query: 221 GMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYG 259
           G+ HSS+PNA+M P Y   D  NFKL +DD++GIQ+LYG
Sbjct: 266 GLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYG 304


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  195 bits (495), Expect = 4e-50
 Identities = 104/212 (49%), Positives = 127/212 (59%), Gaps = 4/212 (1%)

Query: 3   LTVLCAV-CLLPGSLALPLP--QEAGGMS-ELQWEQAQDYLKRFYLYDSETKNANSLEAK 58
           L  LC + CLL  + A P P  +  G ++ +   E A  YL  FY    E+ N   L+  
Sbjct: 14  LRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDT 73

Query: 59  LKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTR 118
           LK+MQKFFGLP TG L+   IE M+KPRCG PDVA Y+ FP  PKW    +TYRI+ YT 
Sbjct: 74  LKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTP 133

Query: 119 DLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAH 178
           DL   TVD   ++A  +W    PL F ++  G ADIMI F R  HGD YPFDG    LAH
Sbjct: 134 DLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAH 193

Query: 179 AFAPGTGLGGDAHFDEDERWTDGSSLGINFLY 210
           AFAPGTG+GGD+HFD+DE WT G    +   Y
Sbjct: 194 AFAPGTGVGGDSHFDDDELWTLGEGQVVRVKY 225



 Score = 74.7 bits (182), Expect = 8e-14
 Identities = 40/98 (40%), Positives = 54/98 (55%), Gaps = 7/98 (7%)

Query: 167 YPFDGPGNTLAHAFAPGTGLGG-----DAHFDEDERWTDGSSLGINFLYAATHELGHSLG 221
           +PF   GN      + G   G       A++D+D +W      G +    A HE GH++G
Sbjct: 351 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 410

Query: 222 MGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYG 259
           + HS DP A+M P Y     +NF+LSQDDIKGIQ+LYG
Sbjct: 411 LEHSQDPGALMAPIYTY--TKNFRLSQDDIKGIQELYG 446


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  195 bits (495), Expect = 4e-50
 Identities = 101/264 (38%), Positives = 153/264 (57%), Gaps = 6/264 (2%)

Query: 1   MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK 60
           M+L +L     LP   A+P+P  A       W+  + Y  +F+L   E+      E + +
Sbjct: 1   MQLVILRVTIFLPWCFAVPVPPAADHKG---WDFVEGYFHQFFLTKKESPLLTQ-ETQTQ 56

Query: 61  EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL 120
            +Q+F     T +L+ ++  ++ +P CGVPD ++ S+ P   KW    +TYRI++Y  D+
Sbjct: 57  LLQQFHRNG-TDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDM 115

Query: 121 PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF 180
               V   +  A+++W    PL F++V  G ADI + F + AH D +PFDGPG  L HAF
Sbjct: 116 KPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAF 175

Query: 181 APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD 240
            P +G  G  HFD++E W+  S  G N    ATHE+GHSLG+ HS + +++MYPTY   D
Sbjct: 176 LPNSGNPGVVHFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHD 234

Query: 241 PQNFKLSQDDIKGIQKLYGKRSNS 264
           P+ F+LS DDI+ IQ LYG++ +S
Sbjct: 235 PRTFQLSADDIQRIQHLYGEKCSS 258


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  189 bits (481), Expect = 2e-48
 Identities = 92/173 (53%), Positives = 109/173 (63%)

Query: 38  YLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSL 97
           YL  FY    E+ N   L+  LK+MQKFFGLP TG L+   IE M+KPRCG PDVA Y+ 
Sbjct: 3   YLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF 62

Query: 98  FPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIG 157
           FP  PKW    +TYRI+ YT DL   TVD   ++A  +W    PL F ++  G ADIMI 
Sbjct: 63  FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN 122

Query: 158 FARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLY 210
           F R  HGD YPFDG    LAHAFAPGTG+GGD+HFD+DE WT G    +   Y
Sbjct: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKY 175



 Score = 74.7 bits (182), Expect = 8e-14
 Identities = 40/98 (40%), Positives = 54/98 (55%), Gaps = 7/98 (7%)

Query: 167 YPFDGPGNTLAHAFAPGTGLGG-----DAHFDEDERWTDGSSLGINFLYAATHELGHSLG 221
           +PF   GN      + G   G       A++D+D +W      G +    A HE GH++G
Sbjct: 301 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 360

Query: 222 MGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYG 259
           + HS DP A+M P Y     +NF+LSQDDIKGIQ+LYG
Sbjct: 361 LEHSQDPGALMAPIYTY--TKNFRLSQDDIKGIQELYG 396


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score =  182 bits (461), Expect = 3e-46
 Identities = 103/259 (39%), Positives = 136/259 (52%), Gaps = 19/259 (7%)

Query: 23  EAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIM 82
           ++   S   W Q   YL    L     ++  SL A +  MQKF+GL +TG  ++  ++ M
Sbjct: 29  QSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAM 88

Query: 83  QKPRCGVPDVAEYSLFPN---------SPKWTSKVVTYRIVSYTRDLPHITVDRLVSKAL 133
           ++PRCGVPD     +  N           KW    +T+ I +YT  +        + KA 
Sbjct: 89  RRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAF 148

Query: 134 NMWGKEIPLHFRKVVWG--------TADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTG 185
            +W    PL FR+V +          ADIMI FA G HGDS PFDG G  LAHA+ PG  
Sbjct: 149 RVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN 208

Query: 186 LGGDAHFDEDERWT--DGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQN 243
           +GGD HFD  E WT  +    G +    A HELGH+LG+ HSSDP+A+M P Y   D +N
Sbjct: 209 IGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTEN 268

Query: 244 FKLSQDDIKGIQKLYGKRS 262
           F L  DD +GIQ+LYG  S
Sbjct: 269 FVLPDDDRRGIQQLYGGES 287


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score =  180 bits (457), Expect = 1e-45
 Identities = 100/248 (40%), Positives = 137/248 (55%), Gaps = 22/248 (8%)

Query: 32  WEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPD 91
           W Q   YL       S  ++A ++++ L  MQ+F+G+ +TG ++   I+ M+KPRCGVPD
Sbjct: 46  WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105

Query: 92  VAE-----------YSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEI 140
                         Y+L     KW  K +TY I + T  +      + + +A ++W    
Sbjct: 106 QTRGSSKFHIRRKRYAL--TGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVT 163

Query: 141 PLHFRKVVWGT-------ADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFD 193
           PL F +V +          DI I FA G HGDS PFDG G  LAHA+ PG G+GGD HFD
Sbjct: 164 PLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFD 223

Query: 194 EDERWTDGSSL--GINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDI 251
            DE WT G+    G +    A HELGH+LG+ HS+DP A+M P Y   +  NFKL  DD+
Sbjct: 224 SDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDL 283

Query: 252 KGIQKLYG 259
           +GIQK+YG
Sbjct: 284 QGIQKIYG 291


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score =  180 bits (457), Expect = 1e-45
 Identities = 100/248 (40%), Positives = 137/248 (55%), Gaps = 22/248 (8%)

Query: 32  WEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPD 91
           W Q   YL       S  ++A ++++ L  MQ+F+G+ +TG ++   I+ M+KPRCGVPD
Sbjct: 46  WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105

Query: 92  VAE-----------YSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEI 140
                         Y+L     KW  K +TY I + T  +      + + +A ++W    
Sbjct: 106 QTRGSSKFHIRRKRYAL--TGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVT 163

Query: 141 PLHFRKVVWGT-------ADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFD 193
           PL F +V +          DI I FA G HGDS PFDG G  LAHA+ PG G+GGD HFD
Sbjct: 164 PLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFD 223

Query: 194 EDERWTDGSSL--GINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDI 251
            DE WT G+    G +    A HELGH+LG+ HS+DP A+M P Y   +  NFKL  DD+
Sbjct: 224 SDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDL 283

Query: 252 KGIQKLYG 259
           +GIQK+YG
Sbjct: 284 QGIQKIYG 291


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score =  180 bits (457), Expect = 1e-45
 Identities = 112/280 (40%), Positives = 151/280 (53%), Gaps = 23/280 (8%)

Query: 1   MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK 60
           +RL  L  + L P + A P P        + W     YL   +   ++ ++   L   +K
Sbjct: 5   LRLLALLLLLLAPPARA-PKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIK 63

Query: 61  EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVA----------EYSLFPNSPKWTSKVVT 110
            MQ+F GLP TG ++   +  M+KPRC +PDV            Y+L  +   W  + +T
Sbjct: 64  VMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYAL--SGSVWKKRTLT 121

Query: 111 YRIVSYTRD--LPHITVDRLVSKALNMWGKEIPLHFRKV---VWGTADIMIGFARGAHGD 165
           +R+ S+ +   L   TV  L+S AL  WG E  L F +V        DI+I FAR  H D
Sbjct: 122 WRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQD 181

Query: 166 SYPFDGPGNTLAHAFAPGT-GLGGDAHFDEDERWTDGS--SLGINFLYAATHELGHSLGM 222
           SYPFDG G TLAHAF PG   + GD HFD++E WT GS    G +    A HE GH+LG+
Sbjct: 182 SYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGL 241

Query: 223 GHSSDPNAVMYPTYGN--GDPQNFKLSQDDIKGIQKLYGK 260
           GHSS PN++M P Y    GDP  ++LSQDD  G+Q+LYGK
Sbjct: 242 GHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGK 281


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score =  158 bits (400), Expect = 4e-39
 Identities = 90/258 (34%), Positives = 134/258 (51%), Gaps = 13/258 (5%)

Query: 19  PLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRV 78
           P P+       ++W     YL        + +    L   +  MQ+F GL  TG+L+   
Sbjct: 42  PAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEAT 101

Query: 79  IEIMQKPRCGVPDVAEYSLF------PNSPKWTSKVVTYRIVSYTRDLP--HITVDRLVS 130
           + +M+ PRC +PD+   +        P   KW  + +++R+ ++ RD P  H TV  L+ 
Sbjct: 102 LALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMY 161

Query: 131 KALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPG-TGLGGD 189
            AL +W    PL+F +V    ADI I F++  H D YPFDGPG T+AHAF PG     GD
Sbjct: 162 YALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGD 221

Query: 190 AHFDEDERWTDGSS--LGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGN--GDPQNFK 245
            HFD+DE WT  SS   G++    A HE GH++G+ H +  +++M P Y    GDP  + 
Sbjct: 222 THFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYG 281

Query: 246 LSQDDIKGIQKLYGKRSN 263
           L  +D   + +LYG R +
Sbjct: 282 LPYEDKVRVWQLYGVRES 299


>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
           [Homo sapiens]
          Length = 508

 Score =  147 bits (370), Expect = 1e-35
 Identities = 89/237 (37%), Positives = 126/237 (53%), Gaps = 18/237 (7%)

Query: 37  DYLKRFYLYDSETKNANSLEAK-----LKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPD 91
           DYL ++       + +N+ + +     L+  Q+   LP++G L+      M++PRCG+ D
Sbjct: 30  DYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89

Query: 92  -----VAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRK 146
                  +Y L     +W  K +T+RI++    LP  T    + +A   W    PL F++
Sbjct: 90  PFNQKTLKYLLLG---RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQE 146

Query: 147 VVWGTADIMIGF-ARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLG 205
           V  G ADI + F  R +   S  FDGPG  LAHA  P  G     HFDEDE WT+G+  G
Sbjct: 147 VQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELG---SVHFDEDEFWTEGTYRG 203

Query: 206 INFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRS 262
           +N    A HE+GH+LG+GHS    A+M P Y  G   +FKL  DD+ GIQ LYGK+S
Sbjct: 204 VNLRIIAAHEVGHALGLGHSRYSQALMAPVY-EGYRPHFKLHPDDVAGIQALYGKKS 259


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score =  144 bits (364), Expect = 6e-35
 Identities = 81/187 (43%), Positives = 102/187 (54%), Gaps = 10/187 (5%)

Query: 82  MQKPRCGVPDVAEYSLFPNSPK--------WTSKVVTYRIVSYTRDLPHITVDRLVSKAL 133
           ++ PRCGVPD ++     N  K        W    +TYRI+ +   L    V + +++AL
Sbjct: 75  LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEAL 134

Query: 134 NMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFD 193
            +W    PL F +V  G ADIMI FAR  HGD  PFDGPG  LAHAF P T   GD HFD
Sbjct: 135 KVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFD 194

Query: 194 EDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKG 253
            DE WT G   G + L  A HE GH LG+ H++   A+M   Y    P    LS DD +G
Sbjct: 195 YDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRYP--LSLSPDDCRG 252

Query: 254 IQKLYGK 260
           +Q LYG+
Sbjct: 253 VQHLYGQ 259


>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score =  141 bits (356), Expect = 5e-34
 Identities = 73/172 (42%), Positives = 99/172 (57%), Gaps = 2/172 (1%)

Query: 35  AQDYLKRF-YLYDSETKN-ANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDV 92
           A++YL R+ Y   +E +  + SL   L  +QK   LP TG L+S  ++ M+ PRCGVPD+
Sbjct: 45  AEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDL 104

Query: 93  AEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTA 152
             +  F    KW    +TY I +Y+ DLP   +D   ++A  +W    PL F +V    A
Sbjct: 105 GRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDA 164

Query: 153 DIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSL 204
           DI+I F    HGD YPFDG    LAHAF PG G+ GDAHFD+DE W+ G  +
Sbjct: 165 DIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGV 216



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 38/102 (37%), Positives = 52/102 (50%), Gaps = 11/102 (10%)

Query: 167 YPFDGPGNTLAHAFAPGTGLGG-----DAHFDEDERWTDGSSLGINFLYAATHELGHSLG 221
           +PF   G   +   + G G G       ++FD D++W      G +    A HE GH+LG
Sbjct: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALG 408

Query: 222 MGHSSDPNAVMYPTY--GNGDPQNFKLSQDDIKGIQKLYGKR 261
           + HSS P A+MYP Y    G P    L +DD+ GI+ LYG R
Sbjct: 409 LDHSSVPEALMYPMYRFTEGPP----LHKDDVNGIRHLYGPR 446


>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
           [Homo sapiens]
          Length = 520

 Score =  133 bits (335), Expect = 1e-31
 Identities = 90/268 (33%), Positives = 130/268 (48%), Gaps = 34/268 (12%)

Query: 21  PQEAGGMSELQWEQAQDYLKRF-YLYDSETKNANSLEAK--LKEMQKFFGLPITGMLNSR 77
           P E GG  EL+ ++A+ +L+++ YL +   K   S      ++  Q    LP++G+L+  
Sbjct: 24  PAERGGQ-ELR-KEAEAFLEKYGYLNEQVPKAPTSTRFSDAIRAFQWVSQLPVSGVLDRA 81

Query: 78  VIEIMQKPRCGVPDVAEYSLFPN----------------------SPKWTSKVVTYRIVS 115
            +  M +PRCGV D   Y+ +                          KW  + ++YR+V+
Sbjct: 82  TLRQMTRPRCGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVN 141

Query: 116 YTRDLPHITVDRLVSKALNMWGKEIPLHFRKV-VWGTADIMIGFARGAHGDSY--PFDGP 172
           +   LP   V   V  A  +W     L F +    G ADI + F +G H D     FDGP
Sbjct: 142 WPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGP 201

Query: 173 GNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVM 232
           G  LAHAF P  G   +AHFD+DERW+     G N      HE+GH+LG+ HS  P A+M
Sbjct: 202 GGALAHAFLPRRG---EAHFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALM 258

Query: 233 YPTYGNGDPQNFKLSQDDIKGIQKLYGK 260
            P Y     ++  LS DD+  +Q LYGK
Sbjct: 259 APYYKRLG-RDALLSWDDVLAVQSLYGK 285


>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
           sapiens]
          Length = 569

 Score =  108 bits (270), Expect = 5e-24
 Identities = 80/261 (30%), Positives = 117/261 (44%), Gaps = 50/261 (19%)

Query: 48  ETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDV--------------- 92
           ET    +L   ++  Q+   LP +G L++  +  M +PRCGVPD+               
Sbjct: 78  ETPKGAALAEAVRRFQRANALPASGELDAATLAAMNRPRCGVPDMRPPPPSAPPSPPGPP 137

Query: 93  --AEYSLFPNSP--------------------KWTSKVVTYRIVSYTRDLPHITVD--RL 128
             A     P +P                     ++ + +++R++           D  R+
Sbjct: 138 PRARSRRSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRTLSWRLLGEALSSQLSVADQRRI 197

Query: 129 VSKALNMWGKEIPLHFRKVV---WGTADIMIGFARGAH-GDSYPFDGPGNTLAHAFAPGT 184
           V+ A  MW +  PL FR+ +       DI +GF RG H G    FDG G   AHA+  G 
Sbjct: 198 VALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHAWRLG- 256

Query: 185 GLGGDAHFDEDERWTDGSS-LGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQN 243
               D HFD+DE +T  +S  GI+ L  A HE+GH LG+ H+    ++M P Y   +P  
Sbjct: 257 ----DIHFDDDEHFTPPTSDTGISLLKVAVHEIGHVLGLPHTYRTGSIMQPNYIPQEPA- 311

Query: 244 FKLSQDDIKGIQKLYGKRSNS 264
           F+L   D K IQKLYG    S
Sbjct: 312 FELDWSDRKAIQKLYGSCEGS 332


>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
          Length = 390

 Score = 88.6 bits (218), Expect = 5e-18
 Identities = 67/188 (35%), Positives = 96/188 (51%), Gaps = 25/188 (13%)

Query: 90  PDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL--PHITVDRLVSKALNMWGKEIPLHFRKV 147
           P    Y+L P   +W    +TYRI+S+ R+L  P  T  R ++ A  MW    P  FR+V
Sbjct: 74  PRRRRYTLTPARLRWDHFNLTYRILSFPRNLLSPRET-RRALAAAFRMWSDVSPFSFREV 132

Query: 148 V-WGTADIMIGFARGAHGDS------YPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTD 200
                +D+ IGF    H D       + FDGP   LAHAF P  G     HFD+ E W  
Sbjct: 133 APEQPSDLRIGFYPINHTDCLVSALHHCFDGPTGELAHAFFPPHG---GIHFDDSEYWVL 189

Query: 201 GSSL-----GI---NFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFK-LSQDDI 251
           G +      G+   + ++ A HE+GH+LG+ HS    A+M+    N   + +K LSQD++
Sbjct: 190 GPTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQHGRALMHL---NATLRGWKALSQDEL 246

Query: 252 KGIQKLYG 259
            G+ +LYG
Sbjct: 247 WGLHRLYG 254


>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 1/86 (1%)

Query: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAH-GDSYPFDGPG 173
           +Y  +LP   VDR   KA  +W K   L F +      DI++ F   A   D+ PF G  
Sbjct: 28  NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87

Query: 174 NTLAHAFAPGTGLGGDAHFDEDERWT 199
             LAHAF PG G+GGD HFD DE  T
Sbjct: 88  GCLAHAFPPGPGIGGDVHFDNDETRT 113


>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 358

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAH-GDSYPFDGPG 173
           +Y  +LP   VDR   KA  +W     L F +      DI++ F   A   D+ PF G  
Sbjct: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 247

Query: 174 NTLAHAFAPGTGLGGDAHFDEDERWT 199
             LAHAF PG G+GGD HFD DE  T
Sbjct: 248 GCLAHAFPPGPGIGGDVHFDNDETRT 273


>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAH-GDSYPFDGPG 173
           +Y  +LP   VDR   KA  +W     L F +      DI++ F   A   D+ PF G  
Sbjct: 28  NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87

Query: 174 NTLAHAFAPGTGLGGDAHFDEDERWT 199
             LAHAF PG G+GGD HFD DE  T
Sbjct: 88  GCLAHAFPPGPGIGGDVHFDNDETRT 113


>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
           sapiens]
          Length = 183

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 14/148 (9%)

Query: 37  DYLKRFYLYDSETKNANSLEAK-----LKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPD 91
           DYL ++       + +N+ + +     L+  Q+   LP++G L+      M++PRCG+ D
Sbjct: 30  DYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89

Query: 92  -----VAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRK 146
                  +Y L     +W  K +T+RI++    LP  T    + +A   W    PL F++
Sbjct: 90  PFNQKTLKYLLLG---RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQE 146

Query: 147 VVWGTADIMIGF-ARGAHGDSYPFDGPG 173
           V  G ADI + F  R +   S  FDGPG
Sbjct: 147 VQAGAADIRLSFHGRQSSYCSNTFDGPG 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,112,281
Number of Sequences: 37866
Number of extensions: 504761
Number of successful extensions: 1163
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1045
Number of HSP's gapped (non-prelim): 60
length of query: 267
length of database: 18,247,518
effective HSP length: 100
effective length of query: 167
effective length of database: 14,460,918
effective search space: 2414973306
effective search space used: 2414973306
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.