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Search of human proteins with 4505213
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505213 matrix metalloproteinase 19 isoform rasi-1
preproprotein [Homo sapiens]
(508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot... 1068 0.0
gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ... 360 2e-99
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 267 1e-71
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens] 256 3e-68
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ... 256 4e-68
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 252 6e-67
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens] 250 2e-66
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap... 244 2e-64
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi... 241 1e-63
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi... 231 2e-60
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens] 230 3e-60
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens] 221 1e-57
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens] 216 4e-56
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H... 210 2e-54
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi... 207 2e-53
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens] 204 2e-52
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 203 3e-52
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi... 193 4e-49
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 183 4e-46
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein... 164 2e-40
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi... 158 1e-38
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 151 2e-36
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 151 2e-36
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens] 147 3e-35
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi... 134 2e-31
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 112 1e-24
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens] 105 7e-23
gi|11321561 hemopexin precursor [Homo sapiens] 69 1e-11
gi|88853069 vitronectin precursor [Homo sapiens] 63 6e-10
gi|73808271 matrix metalloproteinase 28 isoform 3 [Homo sapiens] 51 3e-06
>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
[Homo sapiens]
Length = 508
Score = 1068 bits (2761), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60
MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
Sbjct: 1 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60
Query: 61 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120
QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
Sbjct: 61 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120
Query: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA 180
PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA
Sbjct: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA 180
Query: 181 DIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH 240
DIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH
Sbjct: 181 DIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH 240
Query: 241 FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP 300
FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP
Sbjct: 241 FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP 300
Query: 301 RGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRY 360
RGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRY
Sbjct: 301 RGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRY 360
Query: 361 INFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKG 420
INFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKG
Sbjct: 361 INFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKG 420
Query: 421 LFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCRPRTIDTT 480
LFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCRPRTIDTT
Sbjct: 421 LFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCRPRTIDTT 480
Query: 481 PSGGNTTPSGTGITLDTTLSATETTFEY 508
PSGGNTTPSGTGITLDTTLSATETTFEY
Sbjct: 481 PSGGNTTPSGTGITLDTTLSATETTFEY 508
>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
sapiens]
Length = 183
Score = 360 bits (924), Expect = 2e-99
Identities = 175/175 (100%), Positives = 175/175 (100%)
Query: 1 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60
MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
Sbjct: 1 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60
Query: 61 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120
QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
Sbjct: 61 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120
Query: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGR 175
PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGR
Sbjct: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGR 175
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 267 bits (683), Expect = 1e-71
Identities = 178/507 (35%), Positives = 252/507 (49%), Gaps = 60/507 (11%)
Query: 24 AEVAPVDYLSQYGYLQK-PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQ 82
A A ++L YGYL S + + A+ Q+ +PV+G LD T M++
Sbjct: 77 APFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKK 136
Query: 83 PRCGLED----PFNQKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWS 137
PRCG+ D ++ +Y L G +WR+KH+T+ I N + R A+RQAF W
Sbjct: 137 PRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQ 196
Query: 138 NVAPLTFQEV-------QAGAADIRL----SFHGRQSSYCSNTFDGPGRVLAHADIPEL- 185
V PLTF+EV ADI + FHG S+ FDG G LAHA P
Sbjct: 197 KVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGD-----SSPFDGEGGFLAHAYFPGPG 251
Query: 186 --GSVHFDEDEFWTEG--TYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH- 240
G HFD DE WT G + G +L ++A HE+GHALGL HS A+MAP Y+ H
Sbjct: 252 IGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHN 311
Query: 241 FKLHPDDVAGIQALYGKKS------------PVIR-----DEEEEETELPTVPPV---PT 280
FKL DD+ GIQ +YG + PV R + + E P PP+ P+
Sbjct: 312 FKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPS 371
Query: 281 EPSPMPDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDS--GPGPLFRVSALWEGLPGNLD 338
P P+ C + + L RG+ + FK + W + ++ G ++ W+GLP +D
Sbjct: 372 TPGTKPNICDGNFNTVALF-RGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARID 430
Query: 339 AAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRV-----EPNLDAALYWPLNQKVF 393
AA +++ FFKGDK W + + PG+P L + +D AL W K +
Sbjct: 431 AAYERADGRFV-FFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTY 489
Query: 394 LFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDG-RVYFFKGKVYWRL- 451
FKG YW++ E R YPKPI ++ G+P P A ++G YF+KG+ YW+
Sbjct: 490 FFKGERYWRYSEERRATDPGYPKPIT-VWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFD 548
Query: 452 NQQLRVEKGYPRNISHNWMHCRPRTID 478
NQ+L VE GYPRNI +WM C + ++
Sbjct: 549 NQKLSVEPGYPRNILRDWMGCNQKEVE 575
>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
Length = 582
Score = 256 bits (655), Expect = 3e-68
Identities = 176/517 (34%), Positives = 254/517 (49%), Gaps = 59/517 (11%)
Query: 11 LLPMTVSGRVLGL------AEVAPVDYLSQYGYLQK-PLEGSNNFKPEDITEALRAFQEA 63
LLP+ G L + +P +L QYGYL L P+ ++ A+ A Q+
Sbjct: 12 LLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKF 71
Query: 64 SELPVSGQLDDATRARMRQPRCGLEDPF------NQKTLKYLLLG-RWRKKHLTFRILNL 116
L V+G+ D T MR+PRCG+ D F N + +Y + G +W+ +TF I N
Sbjct: 72 YGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNY 131
Query: 117 PSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAG--------AADIRL----SFHGRQSS 164
+ + A+R+AF+ W + PL F+EV ADI + FHG
Sbjct: 132 TPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGD--- 188
Query: 165 YCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWT--EGTYRGVNLRIIAAHEVGHALG 219
S FDG G LAHA P G HFD E WT G ++ ++A HE+GHALG
Sbjct: 189 --STPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALG 246
Query: 220 LGHSRYSQALMAPVYEGY-RPHFKLHPDDVAGIQALYGKKS--PVIRDEEEEETELPTVP 276
L HS A+MAP Y+ +F L DD GIQ LYG +S P + T P+VP
Sbjct: 247 LEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSVP 306
Query: 277 PVPTEPSPMPDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSG--PGPLFRVSALWEGLP 334
P P+ P+ C D + + RG+ + FK + W V ++ G + W GLP
Sbjct: 307 DKPKNPTYGPNICDGNFDTVAM-LRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLP 365
Query: 335 GNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRV-----EPNLDAALYWPLN 389
+++ A Y + FFKGDK W + + PG+PK + + +DAAL+W N
Sbjct: 366 ASINTA-YERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPN 424
Query: 390 QKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAA-MSWQDGRVYFFKGKVY 448
K + F+G+ Y++++E R S YPK IK ++ G+P P + M + YF+KG Y
Sbjct: 425 GKTYFFRGNKYYRFNEELRAVDSEYPKNIK-VWEGIPESPRGSFMGSDEVFTYFYKGNKY 483
Query: 449 WRL-NQQLRVEKGYPRNISHNWMHCRPRTIDTTPSGG 484
W+ NQ+L+VE GYP++ +WM C PSGG
Sbjct: 484 WKFNNQKLKVEPGYPKSALRDWMGC--------PSGG 512
>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
[Homo sapiens]
Length = 520
Score = 256 bits (653), Expect = 4e-68
Identities = 167/458 (36%), Positives = 240/458 (52%), Gaps = 41/458 (8%)
Query: 31 YLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDP 90
+L +YGYL + + + ++A+RAFQ S+LPVSG LD AT +M +PRCG+ D
Sbjct: 39 FLEKYGYLNEQVPKAPT--STRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTDT 96
Query: 91 FN-------------------QKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALR 130
+ ++ ++ G +W K+HL++R++N P LP R A+R
Sbjct: 97 NSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPAVRGAVR 156
Query: 131 QAFQDWSNVAPLTFQEVQA-GAADIRLSF-HGRQSSYCSNTFDGPGRVLAHADIPELGSV 188
AFQ WSNV+ L F E A G ADIRL+F G + N FDGPG LAHA +P G
Sbjct: 157 AAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRRGEA 216
Query: 189 HFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPDDV 248
HFD+DE W+ RG NL ++ AHE+GH LGL HS +ALMAP Y+ L DDV
Sbjct: 217 HFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGRDALLSWDDV 276
Query: 249 AGIQALYGKK---SPVIRDEEEEETELPT---VPPVPTEPSPM-PDPCSSELDAMMLGPR 301
+Q+LYGK S ++ + T+ T P P P C S DA+ + +
Sbjct: 277 LAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYCHSSFDAITVDRQ 336
Query: 302 GKTYAFKGDYVWTVSDSG----PGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKV 357
+ Y FKG + W V+ G P PL W GLP N++AA S +FFKG +
Sbjct: 337 QQLYIFKGSHFWEVAADGNVSEPRPL---QERWVGLPPNIEAAAVSLNDGDFYFFKGGRC 393
Query: 358 WRYINFKMSPGFPK--KLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYP 415
WR+ K G P+ + + + DAAL++P +++ LFKG+ Y+ YP
Sbjct: 394 WRFRGPKPVWGLPQLCRAGGLPRHPDAALFFPPLRRLILFKGARYYVLARGGLQVEPYYP 453
Query: 416 KPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQ 453
+ ++ + G+P + S A+ DG + FF+ YWRL+Q
Sbjct: 454 RSLQD-WGGIPEEVSGALPRPDGSIIFFRDDRYWRLDQ 490
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 252 bits (643), Expect = 6e-67
Identities = 179/528 (33%), Positives = 268/528 (50%), Gaps = 65/528 (12%)
Query: 31 YLSQYGYLQKPLEGSNNFKP-EDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
+L +YGYL + + E + AL A Q+ + ++G++D T M++PRCG+ D
Sbjct: 46 WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105
Query: 90 P------FNQKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPL 142
F+ + +Y L G +W+ KH+T+ I N+ + R A+R+AF W NV PL
Sbjct: 106 QTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPL 165
Query: 143 TFQEV-----QAGAADIRLS------FHGRQSSYCSNTFDGPGRVLAHADIPEL---GSV 188
TF+EV + G D+ ++ FHG S+ FDG G LAHA P G
Sbjct: 166 TFEEVPYSELENGKRDVDITIIFASGFHGD-----SSPFDGEGGFLAHAYFPGPGIGGDT 220
Query: 189 HFDEDEFWTEG--TYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYR-PHFKLHP 245
HFD DE WT G + G +L ++A HE+GHALGL HS A+MAP Y+ +FKL
Sbjct: 221 HFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPN 280
Query: 246 DDVAGIQALYG---KKSPVIR--------------DEEEEETELPTVPPV--PTEPSPMP 286
DD+ GIQ +YG K P R D + + P PP P+ P P
Sbjct: 281 DDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKP 340
Query: 287 DPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSG--PGPLFRVSALWEGLPGNLDAAVYSP 344
+ C + + + R + + FK + W V ++ G +++ W GLP ++D AVY
Sbjct: 341 NICDGNFNTLAI-LRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSID-AVYEN 398
Query: 345 RTQWIHFFKGDKVWRYINFKMSPGFPKKL----NRVEPN-LDAALYWPLNQKVFLFKGSG 399
FFKG+K W + + + PG+P L + + P+ +D+A++W K + FKG
Sbjct: 399 SDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDR 458
Query: 400 YWQWDELARTDFSSYPKPIKGLFTGVPNQPSAA-MSWQDGRVYFFKGKVYWRLNQQ-LRV 457
YW++ E +T YPKPI ++ G+P P A + ++G YF+KGK YW+ N Q L+V
Sbjct: 459 YWRYSEEMKTMDPGYPKPIT-VWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKV 517
Query: 458 EKGYPRNISHNWMHCRPRTIDTTPSGGNTTPSGTGIT--LDTTLSATE 503
E GYPR+I ++M C T G++ P I LD T S +
Sbjct: 518 EPGYPRSILKDFMGCDGPT--DRVKEGHSPPDDVDIVIKLDNTASTVK 563
>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
Length = 669
Score = 250 bits (639), Expect = 2e-66
Identities = 180/530 (33%), Positives = 251/530 (47%), Gaps = 98/530 (18%)
Query: 24 AEVAPVDYLSQYGYLQKPLEGSNNFKPEDI-TEALRAFQEASELPVSGQLDDATRARMRQ 82
AEV ++L YGYL +P + + I AL Q +PV+G LD+ T+ M++
Sbjct: 49 AEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKR 108
Query: 83 PRCGLEDPFN--------QKTLKYLLLGR-WRKKHLTFRILNLPSTLPPHTARAALRQAF 133
PRCG+ D F ++ +Y L GR W HLTF I N L + + A+R+AF
Sbjct: 109 PRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAF 168
Query: 134 QDWSNVAPLTFQEVQAGAADIRL--------------SFHGRQSSYCSNTFDGPGRVLAH 179
+ W PL FQEV DIRL FHG S+ FDG G LAH
Sbjct: 169 RVWEQATPLVFQEVPY--EDIRLRRQKEADIMVLFASGFHGD-----SSPFDGTGGFLAH 221
Query: 180 ADIPELG---SVHFDEDEFWTEGT--YRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVY 234
A P G HFD DE WT + G NL ++A HE+GHALGL HS A+MAP Y
Sbjct: 222 AYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFY 281
Query: 235 EGYR-PHFKLHPDDVAGIQALYGKKSPVIRDEEEEETE-LPTV-----------PPVPTE 281
+ +FKL DD+ GIQ LYG D + + T+ LPTV PP P +
Sbjct: 282 QWKDVDNFKLPEDDLRGIQQLYGTP-----DGQPQPTQPLPTVTPRRPGRPDHRPPRPPQ 336
Query: 282 PSPM--------------------------PDPCSSELDAMMLGPRGKTYAFKGDYVWTV 315
P P P+ C + D + + RG+ + FKG + W V
Sbjct: 337 PPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAM-LRGEMFVFKGRWFWRV 395
Query: 316 S-----DSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFP 370
D+ P P + W GLPG++ AA Y + FFKGD+ W + + PG+P
Sbjct: 396 RHNRVLDNYPMP---IGHFWRGLPGDISAA-YERQDGRFVFFKGDRYWLFREANLEPGYP 451
Query: 371 KKLNRV-----EPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGV 425
+ L +D A++W F F+ YW+++E + YPKPI ++ G+
Sbjct: 452 QPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPI-SVWQGI 510
Query: 426 PNQPSAAMSWQDGR-VYFFKGKVYWRL-NQQLRVEKGYPRNISHNWMHCR 473
P P A D YF+KG YW+ N++LR+E GYP++I ++M C+
Sbjct: 511 PASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQ 560
Score = 57.4 bits (137), Expect = 3e-08
Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 388 LNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKV 447
L ++F+FKG W W +YP PI + G+P SAA QDGR FFKG
Sbjct: 380 LRGEMFVFKGR--WFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDR 437
Query: 448 YWRLNQQLRVEKGYPRNISHNWMHCRPRTIDT 479
YW L ++ +E GYP+ ++ + IDT
Sbjct: 438 YW-LFREANLEPGYPQPLTSYGLGIPYDRIDT 468
>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
Length = 603
Score = 244 bits (622), Expect = 2e-64
Identities = 164/496 (33%), Positives = 249/496 (50%), Gaps = 41/496 (8%)
Query: 29 VDYLSQYGYLQK--PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCG 86
V++LS++GYL P G + E++++A+ A Q+ L +G LD+AT A M+ PRC
Sbjct: 53 VEWLSRFGYLPPADPTTGQLQTQ-EELSKAITAMQQFGGLEATGILDEATLALMKTPRCS 111
Query: 87 LED----PFNQKTLKYLLLGRWRKKHLTFRILNLP--STLPPHTARAALRQAFQDWSNVA 140
L D ++ + +W K++L++R+ P S L T RA + A + WS++A
Sbjct: 112 LPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIA 171
Query: 141 PLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIP----ELGSVHFDEDEFW 196
PL F EV AADI++ F + FDGPG +AHA P G HFD+DE W
Sbjct: 172 PLNFHEVAGSAADIQIDF-SKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAW 230
Query: 197 T--EGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYE---GYRPHFKLHPDDVAGI 251
T G++L +A HE GHA+GL H + ++M P Y+ G + L +D +
Sbjct: 231 TFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRV 290
Query: 252 QALYGKKSPVIRDEEEEETELPTVPPVPTEPSP----MPDPCSSELDAMMLGPRGKTYAF 307
LYG + V + EE L PP +P +P CS+ DA + RG+ + F
Sbjct: 291 WQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDA-VAQIRGEAFFF 349
Query: 308 KGDYVWTVS------DSGPGPLFRVSALWEGLPGNLDA--AVYSPRTQW-IHFFKGDKVW 358
KG Y W ++ P + R W GLP +LD+ AVY + I FFKGD+ W
Sbjct: 350 KGKYFWRLTRDRHLVSLQPAQMHR---FWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYW 406
Query: 359 RYINFKMSPGFPKKLNRVE---PNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYP 415
+ + + G+P+ ++ +DAA W N + + FK YW++D+ R YP
Sbjct: 407 VFKDNNVEEGYPRPVSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYP 466
Query: 416 KPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWR-LNQQLRVEKGYPRNISHNWMHCRP 474
L+ GVP+ AM W DG YFF+G+ YW+ L+ +L V GYP++ + +W+ C
Sbjct: 467 AQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGD 525
Query: 475 RTIDTTPSGGNTTPSG 490
D + + G G
Sbjct: 526 SQADGSVAAGVDAAEG 541
>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
sapiens]
Length = 562
Score = 241 bits (615), Expect = 1e-63
Identities = 171/496 (34%), Positives = 237/496 (47%), Gaps = 46/496 (9%)
Query: 29 VDYLSQYGYLQKPLEGSNNFK-PEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGL 87
VD+L++YGYL P + PE + +A++ Q + LP +G++D T A MR+PRC L
Sbjct: 33 VDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSL 92
Query: 88 EDPFN-----QKTLKYLLLGR-WRKKHLTFRILNLP--STLPPHTARAALRQAFQDWSNV 139
D ++ +Y L G W+K+ LT+R+ + P S L T R + A W
Sbjct: 93 PDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGME 152
Query: 140 APLTFQEV---QAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA----DIPELGSVHFDE 192
+ LTF EV Q DI + F R S FDG G LAHA + P G HFD+
Sbjct: 153 SGLTFHEVDSPQGQEPDILIDF-ARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDD 211
Query: 193 DEFWTEGTY--RGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYE---GYRPHFKLHPDD 247
+E WT G+ G +L +A HE GHALGLGHS ++M P Y+ G ++L DD
Sbjct: 212 EETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDD 271
Query: 248 VAGIQALYGK--KSPVIRDEEEEETELPTVPPVPT-EPS-PMPDPCSSELDAMMLGPRGK 303
G+Q LYGK ++P + + P P PT PS P+PD C DA + RG+
Sbjct: 272 RDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDA-IANIRGE 330
Query: 304 TYAFKGDYVWTVSDSG----PGPLFRVSALWEGLPGN---LDAAVYSPRTQWIHFFKGDK 356
T+ FKG + W + SG P P R+ WEGLP + AA R I F G +
Sbjct: 331 TFFFKGPWFWRLQPSGQLVSPRPA-RLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQ 389
Query: 357 VWRYINFKMSPGFPKKLNRVEP---NLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSS 413
W + + ++ G P +DA WP N K +L +G YW++DE A
Sbjct: 390 FWVFQDRQLEGGARPLTELGLPPGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPG 449
Query: 414 YPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRL-NQQLRVEKGYPRNISHNWMHC 472
YP+ + L+ G P P G YFFKG YWR ++ E P+ + NW+ C
Sbjct: 450 YPRDL-SLWEGAPPSPDDVTVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDC 508
Query: 473 RPRTIDTTPSGGNTTP 488
PS G P
Sbjct: 509 ------PAPSSGPRAP 518
>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
sapiens]
Length = 488
Score = 231 bits (588), Expect = 2e-60
Identities = 148/411 (36%), Positives = 209/411 (50%), Gaps = 23/411 (5%)
Query: 80 MRQPRCGLEDPF------NQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAF 133
+R PRCG+ DP N++ L GRW K LT+RIL P L R + +A
Sbjct: 75 LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEAL 134
Query: 134 QDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPEL---GSVHF 190
+ WS+V PLTF EV G ADI + F R FDGPG +LAHA P+ G VHF
Sbjct: 135 KVWSDVTPLTFTEVHEGRADIMIDF-ARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHF 193
Query: 191 DEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPDDVAG 250
D DE WT G +G +L +AAHE GH LGL H+ ++ALM+ Y +R L PDD G
Sbjct: 194 DYDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYT-FRYPLSLSPDDCRG 252
Query: 251 IQALYGKKSPVIRDEEE---EETELPTVPPVPTEPSPMPDPCSSELDAMMLGPRGKTYAF 307
+Q LYG+ P + + + T P EP PD C + DA+ RG+ + F
Sbjct: 253 VQHLYGQPWPTVTSRTPALGPQAGIDTNEIAPLEPDAPPDACEASFDAVST-IRGELFFF 311
Query: 308 KGDYVWTV--SDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFK- 364
K +VW + PG S W+GLP +DAA + I FF+G + W Y K
Sbjct: 312 KAGFVWRLRGGQLQPGYPALASRHWQGLPSPVDAA-FEDAQGHIWFFQGAQYWVYDGEKP 370
Query: 365 -MSPGFPKKLNRVEPNLDAALYW-PLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLF 422
+ P +L V + AAL W P K++ F+G YW++ R S P+ +
Sbjct: 371 VLGPAPLTELGLVRFPVHAALVWGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPRRATD-W 429
Query: 423 TGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQ-QLRVEKGYPRNISHNWMHC 472
GVP++ AA DG YF +G++YW+ + +++ +G+PR + ++ C
Sbjct: 430 RGVPSEIDAAFQDADGYAYFLRGRLYWKFDPVKVKALEGFPRLVGPDFFGC 480
>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
Length = 476
Score = 230 bits (586), Expect = 3e-60
Identities = 156/456 (34%), Positives = 229/456 (50%), Gaps = 30/456 (6%)
Query: 31 YLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDP 90
YL +Y L+K ++ I + ++ Q+ L V+G+LD T MR+PRCG+ D
Sbjct: 37 YLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDV 96
Query: 91 FNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAG 150
+ + + +WRK HLT+RI+N LP +A+ +A + W V PLTF + G
Sbjct: 97 GHFSSFPGM--PKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEG 154
Query: 151 AADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPE---LGSVHFDEDEFWTEGTYRGVNLR 207
ADI +SF ++ +FDGPG LAHA P G +HFD+DE WTE G NL
Sbjct: 155 EADIMISFAVKEHG-DFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDA-SGTNLF 212
Query: 208 IIAAHEVGHALGLGHSRYSQALMAPVYEGYR--PHFKLHPDDVAGIQALYGKKSPVIRDE 265
++AAHE+GH+LGL HS ++ALM P+Y + F+L DDV GIQ+LYG
Sbjct: 213 LVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYG--------P 264
Query: 266 EEEETELPTVP--PVPTEPSPMPDPCSSELDAMMLGP-RGKTYAFKGDYVWTVSDSGPGP 322
TE P VP VP+ S MP C L + RG+ FK Y W S P P
Sbjct: 265 PPASTEEPLVPTKSVPS-GSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEP 323
Query: 323 LFR-VSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRVE---- 377
F +SA W LP LDAA + FKG++ W ++ G+P+ ++ +
Sbjct: 324 EFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPT 383
Query: 378 -PNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQ 436
+DAA+ +K + F YW++DE +++ +P+ I F GV + A +
Sbjct: 384 IRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQ-A 442
Query: 437 DGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHC 472
G YFF G + + R+ + S++W+HC
Sbjct: 443 FGFFYFFSGSSQFEFDPNARMVTHILK--SNSWLHC 476
>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
Length = 477
Score = 221 bits (563), Expect = 1e-57
Identities = 154/455 (33%), Positives = 224/455 (49%), Gaps = 27/455 (5%)
Query: 31 YLSQYGYLQKPLEGSNNFKPED-ITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
YL Y L+K ++ K + + +R Q+ L V+G+LD T MR+PRCG+ D
Sbjct: 37 YLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPD 96
Query: 90 PFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQA 149
+ +T + +WRK HLT+RI+N LP +A+ +A + W V PLTF +
Sbjct: 97 VGHFRTFPGI--PKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYE 154
Query: 150 GAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPE---LGSVHFDEDEFWTEGTYRGVNL 206
G ADI +SF R+ FDGPG VLAHA P G HFD+DE WT+ T G NL
Sbjct: 155 GEADIMISFAVREHG-DFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDT-TGTNL 212
Query: 207 RIIAAHEVGHALGLGHSRYSQALMAPVYEGYR--PHFKLHPDDVAGIQALYGKKSPVIRD 264
++AAHE+GH+LGL HS ++ALM P+Y F+L DD+ GIQ+LYG
Sbjct: 213 FLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGP------P 266
Query: 265 EEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP-RGKTYAFKGDYVWTVSDSGPGP- 322
+ ET L PVP EP P C L + RG+ FK + W S P
Sbjct: 267 PDSPETPLVPTEPVPPEPG-TPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPE 325
Query: 323 LFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRV-----E 377
L +S+ W LP +DAA + FKG++ W ++ G+P+ ++ +
Sbjct: 326 LHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTV 385
Query: 378 PNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQD 437
+DAA+ K + F YW++DE + +PK I F G+ ++ A +
Sbjct: 386 RKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFE-EF 444
Query: 438 GRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHC 472
G YFF G +L +K S++W++C
Sbjct: 445 GFFYFFTGSS--QLEFDPNAKKVTHTLKSNSWLNC 477
>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
Length = 471
Score = 216 bits (550), Expect = 4e-56
Identities = 145/407 (35%), Positives = 205/407 (50%), Gaps = 34/407 (8%)
Query: 53 ITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFR 112
+TE LR Q L V+G+LDD T M++PRCG+ D L +W K +LT+R
Sbjct: 64 MTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTL--KWSKMNLTYR 121
Query: 113 ILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDG 172
I+N + A ++AF+ WS+V PL F + G ADI +SF G + FDG
Sbjct: 122 IVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISF-GIKEHGDFYPFDG 180
Query: 173 PGRVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQAL 229
P +LAHA P G HFD+DE WT + +G NL ++AAHE GH+LGL HS+ AL
Sbjct: 181 PSGLLAHAFPPGPNYGGDAHFDDDETWTSSS-KGYNLFLVAAHEFGHSLGLDHSKDPGAL 239
Query: 230 MAPVYE-GYRPHFKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDP 288
M P+Y + HF L DDV GIQ+LYG DE+ P P P PD
Sbjct: 240 MFPIYTYTGKSHFMLPDDDVQGIQSLYGP-----GDED----------PNPKHPK-TPDK 283
Query: 289 C--SSELDAMMLGPRGKTYAFKGDYVWTV-SDSGPGPLFRVSALWEGLPGNLDAAVYSPR 345
C S LDA + RG+T FK + W + LF + W LP +DAA P
Sbjct: 284 CDPSLSLDA-ITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPS 342
Query: 346 TQWIHFFKGDKVWRYINFKMSPGFPKKLNRV-----EPNLDAALYWPLNQKVFLFKGSGY 400
I F+G K W + + G+PKK++ + + AA+++ K LF G+
Sbjct: 343 HDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQV 402
Query: 401 WQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKV 447
W++D+ YP+ I+ F G+ ++ A ++G +YFF G +
Sbjct: 403 WRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYE-KNGYIYFFNGPI 448
Score = 39.7 bits (91), Expect = 0.007
Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 24/201 (11%)
Query: 284 PMPDPCSSELDAMMLGPR-GKTYAFKGDYVWTVSDSGPGPLFRVSALWEGL--------- 333
P P A GP G F D WT S G LF V+A G
Sbjct: 177 PFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYN-LFLVAAHEFGHSLGLDHSKD 235
Query: 334 PGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPG-------FPKKLNRVEPNLDAALYW 386
PG L +Y+ T HF D + I PG PK ++ +P+L
Sbjct: 236 PGALMFPIYT-YTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAIT 294
Query: 387 PLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQD-GRVYFFKG 445
L + +FK +W+ L + K + +PN+ AA ++ F+G
Sbjct: 295 SLRGETMIFKDRFFWR---LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRG 351
Query: 446 KVYWRLNQQLRVEKGYPRNIS 466
+ +W LN + +GYP+ IS
Sbjct: 352 RKFWALN-GYDILEGYPKKIS 371
>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
sapiens]
Length = 469
Score = 210 bits (535), Expect = 2e-54
Identities = 160/461 (34%), Positives = 225/461 (48%), Gaps = 48/461 (10%)
Query: 31 YLSQYGYLQ---KPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGL 87
YL +Y L+ + +E N P + E L+ QE L V+G+ D T M+QPRCG+
Sbjct: 37 YLEKYYNLKNDGRQVEKRRNSGP--VVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGV 94
Query: 88 EDPFNQKTLKYLLLG---RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTF 144
D +++L RW + HLT+RI N LP A+ +AFQ WSNV PLTF
Sbjct: 95 PD-----VAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTF 149
Query: 145 QEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWTEGTY 201
+V G ADI +SF R ++ FDGPG LAHA P G HFDEDE WT +
Sbjct: 150 TKVSEGQADIMISF-VRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWT-NNF 207
Query: 202 RGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGKKSPV 261
R NL +AAHE+GH+LGL HS ALM P Y + +L DD+ GIQA+YG+
Sbjct: 208 REYNLHRVAAHELGHSLGLSHSTDIGALMYPSYT-FSGDVQLAQDDIDGIQAIYGR---- 262
Query: 262 IRDEEEEETELPTVPPVPTEPSPMPDPCSSEL--DAMMLGPRGKTYAFKGDYVWTVSDSG 319
++ P P P P C S+L DA+ RG+ FK + +
Sbjct: 263 --------SQNPVQPIGPQTPK----ACDSKLTFDAITT-IRGEVMFFKDRFYMRTNPFY 309
Query: 320 PG-PLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKL----- 373
P L +S W LP L+AA + FFKG+K W + G+PK +
Sbjct: 310 PEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFG 369
Query: 374 -NRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAA 432
R ++DAAL K + F + YW++DE R+ YPK I F G+ ++ A
Sbjct: 370 FPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAV 429
Query: 433 MSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCR 473
+DG YFF G ++ + + ++ +++W +CR
Sbjct: 430 F-MKDGFFYFFHGTRQYKFDP--KTKRILTLQKANSWFNCR 467
>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
Length = 470
Score = 207 bits (527), Expect = 2e-53
Identities = 147/429 (34%), Positives = 217/429 (50%), Gaps = 31/429 (7%)
Query: 55 EALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRIL 114
E ++ Q L V+GQLD +T M PRCG+ D + + + + WRK ++T+RI
Sbjct: 62 EKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPV--WRKHYITYRIN 119
Query: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
N + A+R+AFQ WSNV PL F ++ G ADI + F R + + FDG G
Sbjct: 120 NYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVF-ARGAHGDFHAFDGKG 178
Query: 175 RVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMA 231
+LAHA P G HFDEDEFWT + G NL + A HE+GH+LGLGHS +A+M
Sbjct: 179 GILAHAFGPGSGIGGDAHFDEDEFWTTHS-GGTNLFLTAVHEIGHSLGLGHSSDPKAVMF 237
Query: 232 PVYEGYRPH-FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCS 290
P Y+ + F+L DD+ GIQ+LYG + +E LP P +EP+ + DP
Sbjct: 238 PTYKYVDINTFRLSADDIRGIQSLYG--------DPKENQRLPN--PDNSEPA-LCDPNL 286
Query: 291 SELDAMMLGPRGKTYAFKGDYVW-TVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWI 349
S +G K + FK + W VS+ + +S+LW LP ++AA +
Sbjct: 287 SFDAVTTVG--NKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQV 344
Query: 350 HFFKGDKVWRYINFKMSPGFPKKLNRVE-PN----LDAALYWPLNQKVFLFKGSGYWQWD 404
FK DK W N + P +PK ++ PN +DAA++ P + + F + YW++D
Sbjct: 345 FLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYD 404
Query: 405 ELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQL-RVEKGYPR 463
E + YPK I F G+ + A ++ YFF+G + + L R+ K
Sbjct: 405 ERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLK- 463
Query: 464 NISHNWMHC 472
S++W C
Sbjct: 464 --SNSWFGC 470
>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
Length = 403
Score = 204 bits (518), Expect = 2e-52
Identities = 151/428 (35%), Positives = 210/428 (49%), Gaps = 43/428 (10%)
Query: 61 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLG---RWRKKHLTFRILNLP 117
QE L V+G+ D T M+QPRCG+ D +++L RW + HLT+RI N
Sbjct: 2 QEFFGLKVTGKPDAETLKVMKQPRCGVPD-----VAQFVLTEGNPRWEQTHLTYRIENYT 56
Query: 118 STLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVL 177
LP A+ +AFQ WSNV PLTF +V G ADI +SF R ++ FDGPG L
Sbjct: 57 PDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISF-VRGDHRDNSPFDGPGGNL 115
Query: 178 AHADIPEL---GSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVY 234
AHA P G HFDEDE WT +R NL +AAHE+GH+LGL HS ALM P Y
Sbjct: 116 AHAFQPGPGIGGDAHFDEDERWT-NNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY 174
Query: 235 EGYRPHFKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSEL- 293
+ +L DD+ GIQA+YG+ ++ P P P P C S+L
Sbjct: 175 T-FSGDVQLAQDDIDGIQAIYGR------------SQNPVQPIGPQTPK----ACDSKLT 217
Query: 294 -DAMMLGPRGKTYAFKGDYVWTVSDSGPG-PLFRVSALWEGLPGNLDAAVYSPRTQWIHF 351
DA+ RG+ FK + + P L +S W LP L+AA + F
Sbjct: 218 FDAITT-IRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRF 276
Query: 352 FKGDKVWRYINFKMSPGFPKKL------NRVEPNLDAALYWPLNQKVFLFKGSGYWQWDE 405
FKG+K W + G+PK + R ++DAAL K + F + YW++DE
Sbjct: 277 FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDE 336
Query: 406 LARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNI 465
R+ YPK I F G+ ++ A +DG YFF G ++ + + ++
Sbjct: 337 YKRSMDPGYPKMIAHDFPGIGHKVDAVF-MKDGFFYFFHGTRQYKFDP--KTKRILTLQK 393
Query: 466 SHNWMHCR 473
+++W +CR
Sbjct: 394 ANSWFNCR 401
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 203 bits (516), Expect = 3e-52
Identities = 157/482 (32%), Positives = 238/482 (49%), Gaps = 54/482 (11%)
Query: 11 LLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPED---ITEALRAFQEASELP 67
L+ MT + + LA+ YL+Q+ L+ +EG++ + ++ I + +R Q L
Sbjct: 20 LVRMTENEENMQLAQA----YLNQFYSLE--IEGNHLVQSKNRSLIDDKIREMQAFFGLT 73
Query: 68 VSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARA 127
V+G+LD T M+ PRCG+ D Y L G WRK +LT+RI+N P ARA
Sbjct: 74 VTGKLDSNTLEIMKTPRCGVPDVGQYG---YTLPG-WRKYNLTYRIIN----YTPDMARA 125
Query: 128 ALRQAFQD----WSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIP 183
A+ +A Q+ WS V PL F ++ G ADI ++F R C FDGP VL HA P
Sbjct: 126 AVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPLGVLGHAFPP 185
Query: 184 EL---GSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH 240
G HFDEDE WT+ G NL ++AAHE GHALGL HS ALM P Y P
Sbjct: 186 GPGLGGDTHFDEDENWTKDG-AGFNLFLVAAHEFGHALGLSHSNDQTALMFPNYVSLDPR 244
Query: 241 -FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSEL--DAMM 297
+ L DD+ GIQ++YG LP P P EP+ +P C +L DA+
Sbjct: 245 KYPLSQDDINGIQSIYG--------------GLPKEPAKPKEPT-IPHACDPDLTFDAIT 289
Query: 298 LGPRGKTYAFKGDYVWTV-SDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDK 356
R + FKG ++W + D +++ W LP +L AA +PR + I FK +
Sbjct: 290 TF-RREVMFFKGRHLWRIYYDITDVEFELIASFWPSLPADLQAAYENPRDK-ILVFKDEN 347
Query: 357 VWRYINFKMSPGFPKKLNRV-----EPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDF 411
W + + P +PK ++ + +DAA+ +K + F G W++DE+ +T
Sbjct: 348 FWMIRGYAVLPDYPKSIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTMD 407
Query: 412 SSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMH 471
+P+ + F G+ + AA ++ G +F +G + + + + R ++ W
Sbjct: 408 KGFPQRVVKHFPGISIRVDAAFQYK-GFFFFSRGSKQFEYDIKTKNITRIMR--TNTWFQ 464
Query: 472 CR 473
C+
Sbjct: 465 CK 466
>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
Length = 483
Score = 193 bits (490), Expect = 4e-49
Identities = 147/409 (35%), Positives = 196/409 (47%), Gaps = 42/409 (10%)
Query: 57 LRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLG--RWRKKHLTFRIL 114
++ Q L V+G+LD T +++PRCG+ D N + L G +W+K LT+RI
Sbjct: 72 IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYR----LFPGEPKWKKNTLTYRIS 127
Query: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
++ A+ A Q WS+ PL+F + +G ADI +SF S FDGP
Sbjct: 128 KYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGD-SYPFDGPR 186
Query: 175 RVLAHADIPELG---SVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMA 231
LAHA P G HFD E WT GT G NL +AAHE GHALGL HS ALM
Sbjct: 187 GTLAHAFAPGEGLGGDTHFDNAEKWTMGT-NGFNLFTVAAHEFGHALGLAHSTDPSALMY 245
Query: 232 PVYEGYRPH-FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPC- 289
P Y+ P+ F L DDV GIQALYG + + PT+P P +PD C
Sbjct: 246 PTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGK--------PTLPHAPHHKPSIPDLCD 297
Query: 290 -SSELDAM-MLGPRGKTYAFKGDYVWTVS---DSGPGPLFRVSALWEGLPGNLDAAVYSP 344
SS DA+ MLG + FK W +G P +++ + L N+DAA
Sbjct: 298 SSSSFDAVTMLGK--ELLLFKDRIFWRRQVHLRTGIRPS-TITSSFPQLMSNVDAAYEVA 354
Query: 345 RTQWIHFFKGDKVWRYINFKMSP--------GFPKKLNRVEPNLDAALYWPLNQKVFLFK 396
+FFKG W F+M GFP+ + ++ DAA+Y QK F
Sbjct: 355 ERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQI----DAAVYLREPQKTLFFV 410
Query: 397 GSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKG 445
G Y+ +DE R YPK + F+GV Q AA+ +G +YFF G
Sbjct: 411 GDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVE-LNGYIYFFSG 458
Score = 30.4 bits (67), Expect = 4.0
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 388 LNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQD-GRVYFFKGK 446
L +++ LFK +W+ RT P I F + + AA + G YFFKG
Sbjct: 308 LGKELLLFKDRIFWRRQVHLRTGIR--PSTITSSFPQLMSNVDAAYEVAERGTAYFFKGP 365
Query: 447 VYW 449
YW
Sbjct: 366 HYW 368
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 183 bits (464), Expect = 4e-46
Identities = 144/469 (30%), Positives = 213/469 (45%), Gaps = 63/469 (13%)
Query: 30 DYLSQYGYL-QKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLE 88
DYL ++ L + + I E L+ Q L V+G+ ++ T M++PRCG+
Sbjct: 35 DYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVP 94
Query: 89 D-------PFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAP 141
D P N K W + +LT+RI N L A++ AF+ WS +P
Sbjct: 95 DSGGFMLTPGNPK---------WERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASP 145
Query: 142 LTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWTE 198
L F + G ADI ++F+ R ++ FDGP +LAHA P G HFD +E WT
Sbjct: 146 LIFTRISQGEADINIAFYQRDHG-DNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWT- 203
Query: 199 GTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYR--PHFKLHPDDVAGIQALYG 256
T NL ++AAHE GH+LGL HS ALM P Y +R ++ L DD+ GIQA+YG
Sbjct: 204 NTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNY-AFRETSNYSLPQDDIDGIQAIYG 262
Query: 257 KKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSEL--DAMMLGPRGKTYAFKGDYVWT 314
L + P PT PS P PC L DA+ RG+ FK Y W
Sbjct: 263 ---------------LSSNPIQPTGPS-TPKPCDPSLTFDAITT-LRGEILFFKDRYFWR 305
Query: 315 VSDS-GPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKL 373
+ +S W LP + AA I FKG++ W + + G+PK +
Sbjct: 306 RHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDI 365
Query: 374 NRV-----EPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQ 428
+ +DAA+++ K + F +W++D + YPK I G F G+ ++
Sbjct: 366 SNYGFPSSVQAIDAAVFY--RSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESK 423
Query: 429 PSAAMSWQDGRVYFFKGKVYWRLN----QQLRVEKGYPRNISHNWMHCR 473
A Q+ + F G Y+ + + RV +G + W++CR
Sbjct: 424 VDAVFQ-QEHFFHVFSGPRYYAFDLIAQRVTRVARG------NKWLNCR 465
>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
[Homo sapiens]
Length = 457
Score = 164 bits (415), Expect = 2e-40
Identities = 122/372 (32%), Positives = 183/372 (49%), Gaps = 53/372 (14%)
Query: 31 YLSQYGYLQKPLEGSNNFKP-EDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
+L +YGYL + + E + AL A Q+ + ++G++D T M++PRCG+ D
Sbjct: 46 WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105
Query: 90 P------FNQKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPL 142
F+ + +Y L G +W+ KH+T+ I N+ + R A+R+AF W NV PL
Sbjct: 106 QTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPL 165
Query: 143 TFQEV-----QAGAADIRLS------FHGRQSSYCSNTFDGPGRVLAHADIPEL---GSV 188
TF+EV + G D+ ++ FHG S+ FDG G LAHA P G
Sbjct: 166 TFEEVPYSELENGKRDVDITIIFASGFHGD-----SSPFDGEGGFLAHAYFPGPGIGGDT 220
Query: 189 HFDEDEFWTEG--TYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYR-PHFKLHP 245
HFD DE WT G + G +L ++A HE+GHALGL HS A+MAP Y+ +FKL
Sbjct: 221 HFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPN 280
Query: 246 DDVAGIQALYG---KKSPVIR--------------DEEEEETELPTVPPV--PTEPSPMP 286
DD+ GIQ +YG K P R D + + P PP P+ P P
Sbjct: 281 DDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKP 340
Query: 287 DPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSG--PGPLFRVSALWEGLPGNLDAAVYSP 344
+ C + + + R + + FK + W V ++ G +++ W GLP ++DA +
Sbjct: 341 NICDGNFNTLAI-LRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENS 399
Query: 345 RTQWIHF-FKGD 355
++ F KGD
Sbjct: 400 DGNFVFFKVKGD 411
Score = 30.4 bits (67), Expect = 4.0
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 2/59 (3%)
Query: 388 LNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGK 446
L +++F+FK W W YP I + G+P A DG FFK K
Sbjct: 353 LRREMFVFKDQ--WFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSDGNFVFFKVK 409
>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
sapiens]
Length = 569
Score = 158 bits (400), Expect = 1e-38
Identities = 148/502 (29%), Positives = 215/502 (42%), Gaps = 109/502 (21%)
Query: 31 YLSQYGYL-------QKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQP 83
+LS+YG+ P K + EA+R FQ A+ LP SG+LD AT A M +P
Sbjct: 56 FLSRYGWSGVWAAWGPSPEGPPETPKGAALAEAVRRFQRANALPASGELDAATLAAMNRP 115
Query: 84 RCGLED---------------PFNQKTLKY----LLLGR--WR--------------KKH 108
RCG+ D P ++ + L L R W+ K+
Sbjct: 116 RCGVPDMRPPPPSAPPSPPGPPPRARSRRSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRT 175
Query: 109 LTFRILN--LPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAG---AADIRLSFHGRQS 163
L++R+L L S L R + AF+ WS V PL F+E A A DI+L F +
Sbjct: 176 LSWRLLGEALSSQLSVADQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRH 235
Query: 164 SYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTY-RGVNLRIIAAHEVGHALGLGH 222
C FDG G+ AHA LG +HFD+DE +T T G++L +A HE+GH LGL H
Sbjct: 236 LGCPRAFDGSGQEFAHAW--RLGDIHFDDDEHFTPPTSDTGISLLKVAVHEIGHVLGLPH 293
Query: 223 SRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGK-------KSPVIRDEEEEETELPTV 275
+ + ++M P Y P F+L D IQ LYG IR E + E+
Sbjct: 294 TYRTGSIMQPNYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMV- 352
Query: 276 PPVPTEPSPMPDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSGP----GPLFRVSALWE 331
R TY F+ + W + G ++ W
Sbjct: 353 -------------------------RFSTYFFRNSWYWLYENRNNRTRYGDPIQILTGWP 387
Query: 332 GLP-GNLDAAV--YSPRTQWIHFFKGDKVWRYINFK--------MSPGFPKKLNRVEPN- 379
G+P N+DA V ++ + +FF+G++ WRY + K +PK ++ P
Sbjct: 388 GIPTHNIDAFVHIWTWKRDERYFFQGNQYWRYDSDKDQALTEDEQGKSYPKLISEGFPGI 447
Query: 380 ---LDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGV--PNQP----- 429
LD A Y + ++ FK S + +D +SYPK I +F V N P
Sbjct: 448 PSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKRITEVFPAVIPQNHPFRNID 507
Query: 430 SAAMSWQDGRVYFFKGKVYWRL 451
SA S+ ++FFKG YW++
Sbjct: 508 SAYYSYAYNSIFFFKGNAYWKV 529
Score = 30.8 bits (68), Expect = 3.0
Identities = 13/29 (44%), Positives = 18/29 (62%)
Query: 336 NLDAAVYSPRTQWIHFFKGDKVWRYINFK 364
N+D+A YS I FFKG+ W+ +N K
Sbjct: 505 NIDSAYYSYAYNSIFFFKGNAYWKVVNDK 533
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 151 bits (381), Expect = 2e-36
Identities = 99/297 (33%), Positives = 153/297 (51%), Gaps = 25/297 (8%)
Query: 187 SVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPD 246
+ ++D+D W +G +L ++AAHE GHA+GL HS+ ALMAP+Y Y +F+L D
Sbjct: 328 TANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYT-YTKNFRLSQD 386
Query: 247 DVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP-RGKTY 305
D+ GIQ LYG SP + +L T P PT P+ C ++ + RG+ +
Sbjct: 387 DIKGIQELYG-ASP--------DIDLGT-GPTPTLGPVTPEICKQDIVFDGIAQIRGEIF 436
Query: 306 AFKGDYVW---TVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYIN 362
FK ++W T D GPL V+ W LP +DA +P+ + FF G++ W Y
Sbjct: 437 FFKDRFIWRTVTPRDKPMGPLL-VATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSA 495
Query: 363 FKMSPGFPKKLNRV-----EPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKP 417
+ G+PK L + +DAA W N+K ++F G +W+++E+ + +PK
Sbjct: 496 STLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKL 555
Query: 418 IKGLFTGVPNQPSAAMSWQ-DGRVYFFKGKVYWRL-NQQLRVEKGYPRNISHNWMHC 472
I + +P+ A + Q G YFFKG Y +L NQ L+ K +I +W+ C
Sbjct: 556 IADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--GSIKSDWLGC 610
Score = 98.6 bits (244), Expect = 1e-20
Identities = 64/170 (37%), Positives = 84/170 (49%), Gaps = 9/170 (5%)
Query: 41 PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLL 100
P E N F +D L+ Q+ LP +G LD T MR+PRCG D N +
Sbjct: 11 PKESCNLFVLKD---TLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF--FPR 65
Query: 101 LGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHG 160
+W K +T+RI+ L P T A +AFQ WS+V PL F + G ADI ++F G
Sbjct: 66 KPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-G 124
Query: 161 RQSSYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLR 207
R FDG +LAHA P G HFD+DE WT G + V ++
Sbjct: 125 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVK 174
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 151 bits (381), Expect = 2e-36
Identities = 99/297 (33%), Positives = 153/297 (51%), Gaps = 25/297 (8%)
Query: 187 SVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPD 246
+ ++D+D W +G +L ++AAHE GHA+GL HS+ ALMAP+Y Y +F+L D
Sbjct: 378 TANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYT-YTKNFRLSQD 436
Query: 247 DVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP-RGKTY 305
D+ GIQ LYG SP + +L T P PT P+ C ++ + RG+ +
Sbjct: 437 DIKGIQELYG-ASP--------DIDLGT-GPTPTLGPVTPEICKQDIVFDGIAQIRGEIF 486
Query: 306 AFKGDYVW---TVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYIN 362
FK ++W T D GPL V+ W LP +DA +P+ + FF G++ W Y
Sbjct: 487 FFKDRFIWRTVTPRDKPMGPLL-VATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSA 545
Query: 363 FKMSPGFPKKLNRV-----EPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKP 417
+ G+PK L + +DAA W N+K ++F G +W+++E+ + +PK
Sbjct: 546 STLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKL 605
Query: 418 IKGLFTGVPNQPSAAMSWQ-DGRVYFFKGKVYWRL-NQQLRVEKGYPRNISHNWMHC 472
I + +P+ A + Q G YFFKG Y +L NQ L+ K +I +W+ C
Sbjct: 606 IADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--GSIKSDWLGC 660
Score = 98.6 bits (244), Expect = 1e-20
Identities = 64/170 (37%), Positives = 84/170 (49%), Gaps = 9/170 (5%)
Query: 41 PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLL 100
P E N F +D L+ Q+ LP +G LD T MR+PRCG D N +
Sbjct: 61 PKESCNLFVLKD---TLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF--FPR 115
Query: 101 LGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHG 160
+W K +T+RI+ L P T A +AFQ WS+V PL F + G ADI ++F G
Sbjct: 116 KPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-G 174
Query: 161 RQSSYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLR 207
R FDG +LAHA P G HFD+DE WT G + V ++
Sbjct: 175 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVK 224
>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
Length = 267
Score = 147 bits (370), Expect = 3e-35
Identities = 89/237 (37%), Positives = 126/237 (53%), Gaps = 18/237 (7%)
Query: 30 DYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
DYL ++ + +N+ + + L+ Q+ LP++G L+ M++PRCG+ D
Sbjct: 37 DYLKRFYLYDSETKNANSLEAK-----LKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPD 91
Query: 90 PFNQKTLKYLLLG---RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQE 146
+Y L +W K +T+RI++ LP T + +A W PL F++
Sbjct: 92 -----VAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRK 146
Query: 147 VQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELG---SVHFDEDEFWTEGTYRG 203
V G ADI + F R + S FDGPG LAHA P G HFDEDE WT+G+ G
Sbjct: 147 VVWGTADIMIGF-ARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLG 205
Query: 204 VNLRIIAAHEVGHALGLGHSRYSQALMAPVY-EGYRPHFKLHPDDVAGIQALYGKKS 259
+N A HE+GH+LG+GHS A+M P Y G +FKL DD+ GIQ LYGK+S
Sbjct: 206 INFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRS 262
>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
sapiens]
Length = 261
Score = 134 bits (337), Expect = 2e-31
Identities = 79/193 (40%), Positives = 111/193 (57%), Gaps = 12/193 (6%)
Query: 72 LDDATRARMRQPRCGLEDPFNQKTLKYLLLGR--WRKKHLTFRILNLPSTLPPHTARAAL 129
LD A + QP CG+ D + + GR W K LT+RI+N P + P + ++
Sbjct: 69 LDMQMHALLHQPHCGVPDGSDTS----ISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSI 124
Query: 130 RQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELGS-- 187
A WSNV PL FQ+VQ G ADI++SF + + FDGPG +L HA +P G+
Sbjct: 125 YNAVSIWSNVTPLIFQQVQNGDADIKVSF-WQWAHEDGWPFDGPGGILGHAFLPNSGNPG 183
Query: 188 -VHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH-FKLHP 245
VHFD++E W+ + G NL ++A HE+GH+LGL HS ++M P Y + P F+L
Sbjct: 184 VVHFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSA 242
Query: 246 DDVAGIQALYGKK 258
DD+ IQ LYG+K
Sbjct: 243 DDIQRIQHLYGEK 255
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 112 bits (279), Expect = 1e-24
Identities = 93/344 (27%), Positives = 146/344 (42%), Gaps = 56/344 (16%)
Query: 157 SFHGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGH 216
+F G++ S C++ G GR+ + +FD D+ W +G +L ++AAHE GH
Sbjct: 352 TFLGKEYSTCTSEGRGDGRLWCAT------TSNFDSDKKWGFCPDQGYSLFLVAAHEFGH 405
Query: 217 ALGLGHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGKK------------------ 258
ALGL HS +ALM P+Y + LH DDV GI+ LYG +
Sbjct: 406 ALGLDHSSVPEALMYPMYR-FTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAP 464
Query: 259 ------SPVIRDEEEEETELPTVPPV--PTEP-------------SPMPDPCSSELDAMM 297
P E T PT PP PT P SP+ D C+ + +
Sbjct: 465 PTVCPTGPPTVHPSERPTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAI 524
Query: 298 LGPRGKTYAFKGDYVWTVSD---SGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKG 354
+ Y FK W S+ S P F ++ W LP LD+ ++ + FF G
Sbjct: 525 AEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSG 584
Query: 355 DKVWRYINFKMSPGFPKKLNRVEPNLDAALYWPLNQ----KVFLFKGSGYWQWDELARTD 410
+VW Y + P++L+++ D A + K+ LF G W++D A+
Sbjct: 585 RQVWVYTGASVLG--PRRLDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMV 642
Query: 411 FSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQ 454
+ +F GVP +++ + YF + + YWR++ +
Sbjct: 643 DPRSASEVDRMFPGVPLDTHDVFQYRE-KAYFCQDRFYWRVSSR 685
Score = 89.7 bits (221), Expect = 6e-18
Identities = 63/174 (36%), Positives = 86/174 (49%), Gaps = 11/174 (6%)
Query: 30 DYLSQYGYLQ-KPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLE 88
+YL +YGY + + G + + + AL Q+ LP +G+LD AT MR PRCG+
Sbjct: 47 EYLYRYGYTRVAEMRGES----KSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVP 102
Query: 89 DPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQ 148
D +T + L +W ++T+ I N LP A +AF WS V PLTF V
Sbjct: 103 DLGRFQTFEGDL--KWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVY 160
Query: 149 AGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPE---LGSVHFDEDEFWTEG 199
+ ADI + F G FDG +LAHA P G HFD+DE W+ G
Sbjct: 161 SRDADIVIQF-GVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLG 213
>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
Length = 390
Score = 105 bits (263), Expect = 7e-23
Identities = 68/169 (40%), Positives = 96/169 (56%), Gaps = 16/169 (9%)
Query: 103 RWRKKHLTFRILNLP-STLPPHTARAALRQAFQDWSNVAPLTFQEVQAGA-ADIRLSFHG 160
RW +LT+RIL+ P + L P R AL AF+ WS+V+P +F+EV +D+R+ F+
Sbjct: 87 RWDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYP 146
Query: 161 RQSSYC-----SNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYR-----GV---NLR 207
+ C + FDGP LAHA P G +HFD+ E+W G R GV +L
Sbjct: 147 INHTDCLVSALHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTDLV 206
Query: 208 IIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYG 256
+AAHE+GHALGL HS++ +ALM + R L D++ G+ LYG
Sbjct: 207 HVAAHEIGHALGLMHSQHGRALM-HLNATLRGWKALSQDELWGLHRLYG 254
>gi|11321561 hemopexin precursor [Homo sapiens]
Length = 462
Score = 68.9 bits (167), Expect = 1e-11
Identities = 68/225 (30%), Positives = 92/225 (40%), Gaps = 33/225 (14%)
Query: 280 TEPSP-MPDPCSS--ELDAMMLGPRGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGN 336
T+P P + + CS DA L G FKG++VW S +S W+ P
Sbjct: 40 TKPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWK---SHKWDRELISERWKNFPSP 96
Query: 337 LDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRVEPN----LDAALYWPLN--- 389
+DAA + KGDKVW Y K G+PK L P LDAA+
Sbjct: 97 VDAAFRQGHNS-VFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQ 155
Query: 390 -QKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVY 448
+ V F+G W WD LA P G S+A+ W GR Y F+G +
Sbjct: 156 AEGVLFFQGDREWFWD-LATGTMKERSWPAVG-------NCSSALRWL-GRYYCFQGNQF 206
Query: 449 WRLNQ-QLRVEKGYPRNISHNWMHCRPRTIDTTPSGGNTTPSGTG 492
R + + V YPR++ +M C P G+ +GTG
Sbjct: 207 LRFDPVRGEVPPRYPRDVRDYFMPC--------PGRGHGHRNGTG 243
Score = 39.7 bits (91), Expect = 0.007
Identities = 33/140 (23%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Query: 293 LDAMMLGPRGKTYAFKGDYVWTVSDSGPG-PLFRVSALWEGLPGNLDAAVYSPRTQWIHF 351
L A+ G TYAF G + W + S G + ++ W P +DAA + ++
Sbjct: 263 LSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSAVDAAF--SWEEKLYL 320
Query: 352 FKGDKVWRYI---NFKMSPGFPKKLNR--------VEPNLDAALYWPLNQKVFLFKGSGY 400
+G +V+ ++ + + G+PK+L + + ++DAA P + ++ + G
Sbjct: 321 VQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSVDAAFICPGSSRLHIMAGRRL 380
Query: 401 WQWDEL---ARTDFSSYPKP 417
W W +L A+ ++ P P
Sbjct: 381 W-WLDLKSGAQATWTELPWP 399
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 63.2 bits (152), Expect = 6e-10
Identities = 64/258 (24%), Positives = 110/258 (42%), Gaps = 47/258 (18%)
Query: 257 KKSPVIRDEEEE-------------ETELPTVPPVPTEPSPMPDPCSSE-LDAMMLGPRG 302
+++PV++ EEE ++ T+ P +P + CS + DA G
Sbjct: 111 EQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNG 170
Query: 303 KTYAFKGDYVWTVSDSG--PGPLFRVSALWEGLPGNLDAAVYSPRTQW-IHFFKGDKVWR 359
+AF+G Y + + + PG + +W G+ G +DAA Q + FKG + WR
Sbjct: 171 SLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWR 229
Query: 360 YINFKMSPGFPKKL----NRVEPNLDAALYWPLN-----QKVFLFKGSGYWQWDELARTD 410
+ + + P +P+ + + + N+DAAL P + ++V+ FKG YW++
Sbjct: 230 FEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY------Q 283
Query: 411 FSSYP--KPIKGLFTGVPNQPSAAM---SWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNI 465
F P + +G + A M SW+D F G+ Q P+ I
Sbjct: 284 FQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQ--------PQFI 335
Query: 466 SHNWMHCRPRTIDTTPSG 483
S +W H P +D +G
Sbjct: 336 SRDW-HGVPGQVDAAMAG 352
Score = 34.3 bits (77), Expect = 0.28
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 4/37 (10%)
Query: 440 VYFFKGKVYWRLNQQLR----VEKGYPRNISHNWMHC 472
V+FF G Y+R+N + R V+ YPR+I+ W+ C
Sbjct: 436 VFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGC 472
>gi|73808271 matrix metalloproteinase 28 isoform 3 [Homo sapiens]
Length = 130
Score = 50.8 bits (120), Expect = 3e-06
Identities = 26/59 (44%), Positives = 38/59 (64%), Gaps = 2/59 (3%)
Query: 31 YLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
+L +YGYL + + + ++A+RAFQ S+LPVSG LD AT +M +PRCG+ D
Sbjct: 39 FLEKYGYLNEQVPKAPT--STRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTD 95
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,012,338
Number of Sequences: 37866
Number of extensions: 1206924
Number of successful extensions: 5510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 4989
Number of HSP's gapped (non-prelim): 212
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.