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Search of human proteins with 4504705
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform
b [Homo sapiens]
(954 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform ... 1897 0.0
gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform ... 1791 0.0
gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isofor... 1769 0.0
gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isofor... 1750 0.0
gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105k... 672 0.0
gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105k... 672 0.0
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R... 120 8e-27
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 114 6e-25
gi|88703066 copine-like protein [Homo sapiens] 36 0.15
gi|25141328 copine 7 isoform a [Homo sapiens] 35 0.26
gi|7656993 copine 7 isoform b [Homo sapiens] 35 0.26
gi|25141323 copine V [Homo sapiens] 35 0.33
gi|45269137 mitofusin 1 [Homo sapiens] 34 0.57
gi|25121972 copine VIII [Homo sapiens] 34 0.74
gi|126116565 MYC binding protein 2 [Homo sapiens] 33 1.3
gi|34304360 nephrocystin 3 [Homo sapiens] 33 1.7
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 33 1.7
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 33 1.7
gi|18105056 vacuolar protein sorting 33A [Homo sapiens] 32 2.8
gi|189083768 mitofusin 2 [Homo sapiens] 32 2.8
gi|7662004 mitofusin 2 [Homo sapiens] 32 2.8
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom... 32 3.7
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom... 32 3.7
gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo... 30 8.2
gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo... 30 8.2
gi|5730102 transient receptor potential cation channel, subfamil... 30 8.2
gi|157676340 zinc finger protein 142 [Homo sapiens] 30 8.2
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 30 8.2
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 30 8.2
gi|16933559 protocadherin LKC precursor [Homo sapiens] 30 8.2
>gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform b
[Homo sapiens]
Length = 954
Score = 1897 bits (4915), Expect = 0.0
Identities = 954/954 (100%), Positives = 954/954 (100%)
Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTD 600
IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTD
Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTD 600
Query: 601 CVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHD 660
CVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHD
Sbjct: 601 CVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHD 660
Query: 661 DGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLP 720
DGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLP
Sbjct: 661 DGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLP 720
Query: 721 VITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQ 780
VITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQ
Sbjct: 721 VITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQ 780
Query: 781 EVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ 840
EVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ
Sbjct: 781 EVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ 840
Query: 841 AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTRE 900
AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTRE
Sbjct: 841 AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTRE 900
Query: 901 VVTQKNLSGLVPIRDLRLDPSLLCSIPLLALSPNLLIVWLFLSIAYLVTKLRCK 954
VVTQKNLSGLVPIRDLRLDPSLLCSIPLLALSPNLLIVWLFLSIAYLVTKLRCK
Sbjct: 901 VVTQKNLSGLVPIRDLRLDPSLLCSIPLLALSPNLLIVWLFLSIAYLVTKLRCK 954
>gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform a
[Homo sapiens]
Length = 938
Score = 1791 bits (4640), Expect = 0.0
Identities = 900/907 (99%), Positives = 901/907 (99%)
Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTD 600
IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTD
Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTD 600
Query: 601 CVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHD 660
CVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHD
Sbjct: 601 CVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHD 660
Query: 661 DGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLP 720
DGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLP
Sbjct: 661 DGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLP 720
Query: 721 VITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQ 780
VITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQ
Sbjct: 721 VITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQ 780
Query: 781 EVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ 840
EVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ
Sbjct: 781 EVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ 840
Query: 841 AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTRE 900
AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRS G R
Sbjct: 841 AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRR 900
Query: 901 VVTQKNL 907
T KN+
Sbjct: 901 ENTMKNV 907
>gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isoform d
[Homo sapiens]
Length = 977
Score = 1769 bits (4583), Expect = 0.0
Identities = 899/946 (95%), Positives = 900/946 (95%), Gaps = 39/946 (4%)
Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK--------------------------- 573
IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK
Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600
Query: 574 ------------DCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 621
CSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
Sbjct: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660
Query: 622 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 681
APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
Sbjct: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720
Query: 682 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 741
TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
Sbjct: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780
Query: 742 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 801
ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
Sbjct: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840
Query: 802 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 861
LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
Sbjct: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900
Query: 862 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907
RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRS G R T KN+
Sbjct: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNV 946
>gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isoform c
[Homo sapiens]
Length = 972
Score = 1750 bits (4533), Expect = 0.0
Identities = 894/946 (94%), Positives = 895/946 (94%), Gaps = 44/946 (4%)
Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
GAPAAHCQGFKSGGLRKKLHKFEETKKH TSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKH-----TSSGCQSIIYIPQDVVRAKEIIAQINT 415
Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 416 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 475
Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 476 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 535
Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK--------------------------- 573
IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK
Sbjct: 536 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 595
Query: 574 ------------DCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 621
CSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
Sbjct: 596 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 655
Query: 622 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 681
APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
Sbjct: 656 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 715
Query: 682 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 741
TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
Sbjct: 716 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 775
Query: 742 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 801
ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
Sbjct: 776 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 835
Query: 802 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 861
LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
Sbjct: 836 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 895
Query: 862 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907
RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRS G R T KN+
Sbjct: 896 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNV 941
>gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105kD
[Homo sapiens]
Length = 924
Score = 672 bits (1734), Expect = 0.0
Identities = 385/892 (43%), Positives = 555/892 (62%), Gaps = 59/892 (6%)
Query: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+
Sbjct: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95
Query: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
+ F + I + T++KL+VYDVKD+S T+ LG +F V +L
Sbjct: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155
Query: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
L+ + L L+LR+++ +V G I V +M E D + D + L + +
Sbjct: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214
Query: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+
Sbjct: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266
Query: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
+ + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF
Sbjct: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326
Query: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386
Query: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
+FE +++ +G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S
Sbjct: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439
Query: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
L+ +L +L++KT V +L+ +++ L ARP I K SP S+ EE
Sbjct: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497
Query: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGC 559
DQ +M G++S D+ EEEW++VW NV KSL CII VDKL++++ G
Sbjct: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDG----GS 549
Query: 560 EDVFPCAGSCTSKKDCSPPPEESSPG----EWSEALYPLLTTLTDCVAMMSDKAKKAMVF 615
E G+ +K+ P ++ P +W E LYPL+ TL DC+ + ++AK+++ F
Sbjct: 550 EG---SGGNNDGEKE--PSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTF 604
Query: 616 LLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQ 675
+L+Q+ A ++ L L RRD+VF Q L L+CGFIIKL+ L+D GFL+QL+T+GL+ Q
Sbjct: 605 VLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQ 664
Query: 676 FESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPL 735
+E LLSTY +E+ MLEDM++GI DL+ V FK+ +A S+ D+LPVITG R+ + V V L
Sbjct: 665 YEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSN---DVLPVITGRREHYVVEVKL 721
Query: 736 PGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYF 795
P +F++LP +I+ G LL V PVLFNVGINEQQTLAERFGD SLQE IN E+ L Y+
Sbjct: 722 PARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYY 781
Query: 796 EQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTS 855
+ F E +P D + + Q L LL L QN+ ++K KNV+I+W AA ICR+LNG+RFT
Sbjct: 782 KIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTC 841
Query: 856 CKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907
CKSAKDRT+MSVTLEQC IL+ EH + F +AL+CMR G R KN+
Sbjct: 842 CKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNI 893
>gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105kD
[Homo sapiens]
Length = 924
Score = 672 bits (1734), Expect = 0.0
Identities = 385/892 (43%), Positives = 555/892 (62%), Gaps = 59/892 (6%)
Query: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+
Sbjct: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95
Query: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
+ F + I + T++KL+VYDVKD+S T+ LG +F V +L
Sbjct: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155
Query: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
L+ + L L+LR+++ +V G I V +M E D + D + L + +
Sbjct: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214
Query: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+
Sbjct: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266
Query: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
+ + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF
Sbjct: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326
Query: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386
Query: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
+FE +++ +G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S
Sbjct: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439
Query: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
L+ +L +L++KT V +L+ +++ L ARP I K SP S+ EE
Sbjct: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497
Query: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGC 559
DQ +M G++S D+ EEEW++VW NV KSL CII VDKL++++ G
Sbjct: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDG----GS 549
Query: 560 EDVFPCAGSCTSKKDCSPPPEESSPG----EWSEALYPLLTTLTDCVAMMSDKAKKAMVF 615
E G+ +K+ P ++ P +W E LYPL+ TL DC+ + ++AK+++ F
Sbjct: 550 EG---SGGNNDGEKE--PSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTF 604
Query: 616 LLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQ 675
+L+Q+ A ++ L L RRD+VF Q L L+CGFIIKL+ L+D GFL+QL+T+GL+ Q
Sbjct: 605 VLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQ 664
Query: 676 FESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPL 735
+E LLSTY +E+ MLEDM++GI DL+ V FK+ +A S+ D+LPVITG R+ + V V L
Sbjct: 665 YEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSN---DVLPVITGRREHYVVEVKL 721
Query: 736 PGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYF 795
P +F++LP +I+ G LL V PVLFNVGINEQQTLAERFGD SLQE IN E+ L Y+
Sbjct: 722 PARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYY 781
Query: 796 EQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTS 855
+ F E +P D + + Q L LL L QN+ ++K KNV+I+W AA ICR+LNG+RFT
Sbjct: 782 KIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTC 841
Query: 856 CKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907
CKSAKDRT+MSVTLEQC IL+ EH + F +AL+CMR G R KN+
Sbjct: 842 CKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNI 893
>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
exchange factor 1 [Homo sapiens]
Length = 1659
Score = 120 bits (300), Expect = 8e-27
Identities = 101/352 (28%), Positives = 156/352 (44%), Gaps = 45/352 (12%)
Query: 595 LTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKL 654
+ TL D + + K ++ L++ T LQ RRD +FCQ L A +C F +L
Sbjct: 1289 IKTLVDNIQRYVEDGKNQLLLALLK------CTDTELQLRRDAIFCQALVAAVCTFSEQL 1342
Query: 655 RNCL----HDDG------------FLRQLYTIGLLAQFESLLS--TYGEELAMLEDMSLG 696
L +++G +L Q+ G+L +SLLS T EE MLED+ +
Sbjct: 1343 LAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVT 1402
Query: 697 IMDLRNVTFKVTQATSS--ASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLR 754
+ +L NVTF Q + A+ ++ I G+R V L F LP ++ G LR
Sbjct: 1403 LSELDNVTFSFKQLDENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLR 1462
Query: 755 VQPVLFNVGINEQQTLAERFGDTS--LQEVINVESLVRLNSYFEQFKEV-LPEDCLPRSR 811
+ LF + + L + LQ+ IN +SL ++ Y+ + + L LP
Sbjct: 1463 LHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKVQQYYRKLRAFYLERSNLPTDA 1522
Query: 812 SQTC------------LPELLRFLGQNVH----ARKNKNVDILWQAAEICRRLNGVRFTS 855
S T L EL R + VH A + ++ ++E+C RL +
Sbjct: 1523 STTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAGSVGAGLIPISSELCYRLGACQMVM 1582
Query: 856 CKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907
C + R+ +SV+LEQ IL HG+ P+ QA + MR G R + KNL
Sbjct: 1583 CGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNL 1634
Score = 32.7 bits (73), Expect = 1.7
Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 10/124 (8%)
Query: 232 MYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESL- 290
+Y + +T G +LE++ E + + ++ D+ V L LS ++
Sbjct: 856 VYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSSAIVTMP 915
Query: 291 ----RRQIVTQYQTI---ILTYQENLTDLHQYRGPSFKASSLKADKK--LEFVPTNLHIQ 341
R T+ ++I I YQE L P FK + L+ L+F PTN HI
Sbjct: 916 HFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHIN 975
Query: 342 RMRV 345
M V
Sbjct: 976 LMEV 979
>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
Length = 1606
Score = 114 bits (284), Expect = 6e-25
Identities = 190/854 (22%), Positives = 332/854 (38%), Gaps = 163/854 (19%)
Query: 175 EKSDQRPPVTRSVDTVNGRMVLPVDESLTEAL-GIRSKYASLRKDTLLKSVFGGAICRMY 233
+KS +PP + D + ++ +D+ T A+ + ++ SL D + G + Y
Sbjct: 769 QKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEY--GVV---Y 823
Query: 234 RFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARV---CELEELGELSPC---- 286
+ +T G ++E+M E + + ++ L + D V L L E+ P
Sbjct: 824 EYDSTAGIKCNVVEKMIEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQS 883
Query: 287 -WESLRRQIVTQYQTIILTYQENLTDLHQYRGPSFKASSLKADK--KLEFVPTNLHIQRM 343
+ +L + + I +Y++ L P+FK + K +F PTN H+ M
Sbjct: 884 KFSALCSERIEHLCQRISSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVM 943
Query: 344 R---------------VQDDGGSDQNYD--------------------IVTIGAPAAHCQ 368
VQ D ++D I T+ AP+
Sbjct: 944 EVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSL 1003
Query: 369 GFKSG-GLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEI-IAQINTLKTQVS 426
G + G GLR L + E+ T Q ++ Q ++ E+ + QI+ L + ++
Sbjct: 1004 GQQDGHGLRYLLKE--------EDLETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSIT 1055
Query: 427 YYAERLSRAAKDRSATGLERTLAILADKTRQLVTVC-------------DCKLLANSIHG 473
Y + +L R +++ G+ T + R VC D +S
Sbjct: 1056 Y-SPKLER----KTSEGIIPTDSDNEKGERNSKRVCFNVAGDEQEDSGHDTISNRDSYSD 1110
Query: 474 LNAARPDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLN 533
N+ R + IAS S S++ ++ D+ G S+++ +++
Sbjct: 1111 CNSNR-NSIASFTSICSSQCSSYFHSDEMDS------GDELPLSVRISHDKQD------K 1157
Query: 534 VDKSLECIIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKDCSPPPEESSP--------- 584
+ LE + +VD + L G+ F T + +E P
Sbjct: 1158 IHSCLEHLFSQVDSITNL--LKGQAVVRAFDQTKYLTPGRGLQEFQQEMEPKLSCPKRLR 1215
Query: 585 -----GEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVF 639
W+ L + TL + ++ K ++ L++ S Q RRD+VF
Sbjct: 1216 LHIKQDPWN--LPSSVRTLAQNIRKFVEEVKCRLLLALLEYSDS------ETQLRRDMVF 1267
Query: 640 CQTLTALICGFIIKLR---NCLHDDG-------------FLRQLYTIGLLAQFESLLS-T 682
CQTL A +C F +L N + D+ +L Q+ G+L F+SLLS
Sbjct: 1268 CQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQSLLSPN 1327
Query: 683 YGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVI---TGNRDGFNVRVPLPGPL 739
+E AMLED + + DL V+F + +P+ G+R V +
Sbjct: 1328 LTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVYFYIDSYH 1387
Query: 740 FDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEV---INVESLVRLNSYFE 796
F+ LP+ +++G ++ PVLF + + R + S++E IN SL ++ Y +
Sbjct: 1388 FEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYR-DNVSVEEFQAQINAASLEKVKQYNQ 1446
Query: 797 QFKEVLPE--DCLPRSRSQTC-----------LPELLRFLGQNVHARKN----------K 833
+ + + + P S S+ L EL R + + +++
Sbjct: 1447 KLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKRTAACANTACSAS 1506
Query: 834 NVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECM 893
V +L ++E+C RL C S R +SVTLEQ +IL HG+ P+ QA + M
Sbjct: 1507 GVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGLPPRYIMQATDVM 1566
Query: 894 RSIGTREVVTQKNL 907
R G R T KNL
Sbjct: 1567 RKQGARVQNTAKNL 1580
>gi|88703066 copine-like protein [Homo sapiens]
Length = 553
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/135 (20%), Positives = 53/135 (39%), Gaps = 4/135 (2%)
Query: 46 LEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQ 105
+E +++C L K + V + + W + +TE+I+ T NP F+ F
Sbjct: 16 IEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRK--FVL 73
Query: 106 DSLINQMTQVKLSVYDV--KDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRV 163
D + ++ VY+V K LG + +++ + R+ TL +
Sbjct: 74 DYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTLTGVPGKKC 133
Query: 164 GNITVIGWQMEEKSD 178
G I + ++ D
Sbjct: 134 GTILLTAEELSNCRD 148
>gi|25141328 copine 7 isoform a [Homo sapiens]
Length = 558
Score = 35.4 bits (80), Expect = 0.26
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Query: 36 GNIQDPDEPILEFSLACSELHTPSLDRKP--NSFVAVSVTTPPQAFWTKHAQTEIIEGTN 93
G + P +E L+C L LDR P S +V++ Q W + +TE++ +
Sbjct: 14 GGLPAPCASKVELRLSCRHL----LDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSL 69
Query: 94 NPIFLSSIAFFQDSLINQMTQVKLSVYD 121
+P+F S F D ++ +++ VYD
Sbjct: 70 HPVF--SKVFTVDYYFEEVQRLRFEVYD 95
>gi|7656993 copine 7 isoform b [Homo sapiens]
Length = 633
Score = 35.4 bits (80), Expect = 0.26
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Query: 36 GNIQDPDEPILEFSLACSELHTPSLDRKP--NSFVAVSVTTPPQAFWTKHAQTEIIEGTN 93
G + P +E L+C L LDR P S +V++ Q W + +TE++ +
Sbjct: 14 GGLPAPCASKVELRLSCRHL----LDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSL 69
Query: 94 NPIFLSSIAFFQDSLINQMTQVKLSVYD 121
+P+F S F D ++ +++ VYD
Sbjct: 70 HPVF--SKVFTVDYYFEEVQRLRFEVYD 95
>gi|25141323 copine V [Homo sapiens]
Length = 593
Score = 35.0 bits (79), Expect = 0.33
Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 33 SLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGT 92
SLAG+I +E +++C L + K + + W + +TE+I+ T
Sbjct: 15 SLAGSIPATK---VEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNT 71
Query: 93 NNPIFLSSIAFFQDSLINQMTQVKLSVYDVKDRS 126
NP F+ F D + ++ +YDV +S
Sbjct: 72 LNPDFVRK--FIVDYFFEEKQNLRFDLYDVDSKS 103
>gi|45269137 mitofusin 1 [Homo sapiens]
Length = 741
Score = 34.3 bits (77), Expect = 0.57
Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 374 GLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAE 430
G +L +F+ ++ FEEC + S ++ Q +RAK+I+A + + V+ AE
Sbjct: 309 GFHARLQEFQNFEQIFEECISQSAVKT--KFEQHTIRAKQILATVKNIMDSVNLAAE 363
>gi|25121972 copine VIII [Homo sapiens]
Length = 564
Score = 33.9 bits (76), Expect = 0.74
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 46 LEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQ 105
+E S++C L K + + V W + +TE+I+ T NP F+ F
Sbjct: 26 VEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRK--FIL 83
Query: 106 DSLINQMTQVKLSVYDVKDRS 126
D + ++ +YDV +S
Sbjct: 84 DYFFEERENLRFDLYDVDSKS 104
>gi|126116565 MYC binding protein 2 [Homo sapiens]
Length = 4640
Score = 33.1 bits (74), Expect = 1.3
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 24/137 (17%)
Query: 201 SLTEALGIRSKYASLRKDTLLKSVFGGAICRM-YRFPTTDGNHLRILEQMAESVLSLHVP 259
S+T G+ ++ S +K V G I ++ YR PT+DG+ + +Q +E V H+
Sbjct: 1313 SITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPV---HI- 1368
Query: 260 RQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPS 319
L+ AR +E C+ESL + + T++L +E L +G
Sbjct: 1369 -------LKRSFARTVSVE-------CFESLLSILHWSWTTLVLGVEE----LRGLKGFQ 1410
Query: 320 FKASSLKADKKLEFVPT 336
F A+ L + +L FV T
Sbjct: 1411 FTATLLDLE-RLRFVGT 1426
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 32.7 bits (73), Expect = 1.7
Identities = 26/116 (22%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 260 RQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPS 319
+ + K+L E+++A + + + E + +E R ++ Q++ T + + DL
Sbjct: 135 KTYQKILREKESALEAKYQAM-ERAATFEHDRDKVKRQFKIFRETKENEIQDL------- 186
Query: 320 FKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGL 375
L+A ++LE L Q ++V D G SD + + + A C+ + G L
Sbjct: 187 -----LRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWTGGAL 237
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/152 (26%), Positives = 56/152 (36%), Gaps = 14/152 (9%)
Query: 479 PDYIASKASPTSTEEEQVMLRNDQDTL-MARWTGRNSRSSLQVDWHEEEWEKVWLNVDKS 537
P + P E E+ L D T+ MA S+ +H+ E +KS
Sbjct: 966 PGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVE------EKS 1019
Query: 538 LECIIQRVDKLLQKERLHGEGCED-----VFPCAGSCTSKKDCSPPPEESSPGEWSEALY 592
Q D +R G G ED V P T +K+ PP S + EA
Sbjct: 1020 EPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQ--EAPV 1077
Query: 593 PLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPT 624
+ LT C + KA+VF +M+ PT
Sbjct: 1078 NIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPT 1109
>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
sapiens]
Length = 1866
Score = 32.7 bits (73), Expect = 1.7
Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 11/111 (9%)
Query: 249 MAESVLSLHVPRQFVKLLLEEDAARVCELE-ELGELSPCWESLRRQIVTQYQTIILTYQE 307
MAE+ LH+ R KL L ++ V + L +S CW I Q++T+I + +
Sbjct: 890 MAEAASQLHIAR---KLDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQ 946
Query: 308 NLTDLHQYRGPSFKASSLKADKKLEFVPTNLHI--QRMRVQDDGGSDQNYD 356
+ + +GP +A+ L D + +P+ L + +RMR+ G +++ +
Sbjct: 947 ---EPEEQKGPQERAAFL--DSLMLQMPSELPLSSRRMRLTHCGLQEKHLE 992
>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
Length = 596
Score = 32.0 bits (71), Expect = 2.8
Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Query: 807 LPRSRSQTCLPEL--LRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTA 864
+PR RS C L L LG +H R+ ++D++ ++ + F C D+T+
Sbjct: 114 VPR-RSLLCEQRLKDLGVLGSFIH-REEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTS 171
Query: 865 MSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNLSG----LVPIRD--LRL 918
+ + + LQ +G PQ+F + EC R + + ++ +G + P+ D L L
Sbjct: 172 LYHAAKGLMTLQALYGTIPQIFGKG-ECARQVANMMIRMKREFTGSQNSIFPVFDNLLLL 230
Query: 919 DPSLLCSIPL 928
D ++ PL
Sbjct: 231 DRNVDLLTPL 240
>gi|189083768 mitofusin 2 [Homo sapiens]
Length = 757
Score = 32.0 bits (71), Expect = 2.8
Identities = 36/165 (21%), Positives = 64/165 (38%), Gaps = 38/165 (23%)
Query: 305 YQENLTDLHQYRGPSFKASSL------KADKKLEFVPT----NLHIQRMRVQDDGGSDQN 354
Y E + H R SF L +A ++ FV N IQ+ + +GG
Sbjct: 269 YMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGG---- 324
Query: 355 YDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEI 414
G + G + ++ +F+ ++ FEEC + S ++ Q VRAK+I
Sbjct: 325 --------------GALAEGFQVRMFEFQNFERRFEECISQSAVKT--KFEQHTVRAKQI 368
Query: 415 IAQINTLKTQV-------SYYAERLSRAAKDRSATGLERTLAILA 452
+ + + Y E + +DR +++ L +LA
Sbjct: 369 AEAVRLIMDSLHMAAREQQVYCEEMREERQDR-LKFIDKQLELLA 412
>gi|7662004 mitofusin 2 [Homo sapiens]
Length = 757
Score = 32.0 bits (71), Expect = 2.8
Identities = 36/165 (21%), Positives = 64/165 (38%), Gaps = 38/165 (23%)
Query: 305 YQENLTDLHQYRGPSFKASSL------KADKKLEFVPT----NLHIQRMRVQDDGGSDQN 354
Y E + H R SF L +A ++ FV N IQ+ + +GG
Sbjct: 269 YMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGG---- 324
Query: 355 YDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEI 414
G + G + ++ +F+ ++ FEEC + S ++ Q VRAK+I
Sbjct: 325 --------------GALAEGFQVRMFEFQNFERRFEECISQSAVKT--KFEQHTVRAKQI 368
Query: 415 IAQINTLKTQV-------SYYAERLSRAAKDRSATGLERTLAILA 452
+ + + Y E + +DR +++ L +LA
Sbjct: 369 AEAVRLIMDSLHMAAREQQVYCEEMREERQDR-LKFIDKQLELLA 412
>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
sapiens]
Length = 1194
Score = 31.6 bits (70), Expect = 3.7
Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 17/141 (12%)
Query: 421 LKTQVSYYAERLSRAAKD-RSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP 479
++ Q++ +RL + R+ L+ +++L ++ RQLV+ + A+ I+ +
Sbjct: 105 IREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKR 164
Query: 480 DYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLE 539
Y A AS + EQ+ R S L +D+ EEE E V + + E
Sbjct: 165 SYSAGNAS----QLEQLS------------RARRSGGELYIDYEEEEMETVEQSTQRIKE 208
Query: 540 CIIQRVDKLLQKERLHGEGCE 560
D ++++ CE
Sbjct: 209 FRQLTADMQALEQKIQDSSCE 229
>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
sapiens]
Length = 1352
Score = 31.6 bits (70), Expect = 3.7
Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 17/141 (12%)
Query: 421 LKTQVSYYAERLSRAAKD-RSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP 479
++ Q++ +RL + R+ L+ +++L ++ RQLV+ + A+ I+ +
Sbjct: 263 IREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKR 322
Query: 480 DYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLE 539
Y A AS + EQ+ R S L +D+ EEE E V + + E
Sbjct: 323 SYSAGNAS----QLEQLS------------RARRSGGELYIDYEEEEMETVEQSTQRIKE 366
Query: 540 CIIQRVDKLLQKERLHGEGCE 560
D ++++ CE
Sbjct: 367 FRQLTADMQALEQKIQDSSCE 387
>gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo
sapiens]
Length = 1236
Score = 30.4 bits (67), Expect = 8.2
Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 22/143 (15%)
Query: 43 EPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIA 102
E +LE T + + F+ V+VT A KH Q + + +I
Sbjct: 880 EQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQ----------LVMEAIG 929
Query: 103 FFQDSLINQMTQVKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAES-- 160
D + + +K R+ T ++ G +VK LL + +HR+ + +R AE+
Sbjct: 930 KLSDDMRRH--------FRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARA 981
Query: 161 --DRVGNITVIGWQMEEKSDQRP 181
R + + + EE+ ++ P
Sbjct: 982 KRHRALSQAAVEEEEEEEEEEEP 1004
>gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo
sapiens]
Length = 1297
Score = 30.4 bits (67), Expect = 8.2
Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 22/143 (15%)
Query: 43 EPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIA 102
E +LE T + + F+ V+VT A KH Q + + +I
Sbjct: 941 EQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQ----------LVMEAIG 990
Query: 103 FFQDSLINQMTQVKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAES-- 160
D + + +K R+ T ++ G +VK LL + +HR+ + +R AE+
Sbjct: 991 KLSDDMRRH--------FRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARA 1042
Query: 161 --DRVGNITVIGWQMEEKSDQRP 181
R + + + EE+ ++ P
Sbjct: 1043 KRHRALSQAAVEEEEEEEEEEEP 1065
>gi|5730102 transient receptor potential cation channel, subfamily
C, member 6 [Homo sapiens]
Length = 931
Score = 30.4 bits (67), Expect = 8.2
Identities = 44/195 (22%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 329 KKLEFVPTNLHIQR--MRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETK 386
K+L P+ +Q+ D+ G+ ++D+ I AAHCQ ++ + L K +
Sbjct: 190 KRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPI-ILAAHCQEYEI--VHTLLRKGARIE 246
Query: 387 KHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLER 446
+ + C + C Q ++IN K S LS +A L
Sbjct: 247 RPHDYFCKCNDCNQ----KQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSN 302
Query: 447 TLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKASPT-STEEEQVMLRNDQDTL 505
LA+LA+ ++ N L+ D++ +TEE + +L D +TL
Sbjct: 303 ELAVLANIEKEF---------KNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVETL 353
Query: 506 MARWTGRNSRSSLQV 520
+ GR + S L++
Sbjct: 354 QSGDHGRPNLSRLKL 368
>gi|157676340 zinc finger protein 142 [Homo sapiens]
Length = 1687
Score = 30.4 bits (67), Expect = 8.2
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 42 DEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPP 76
+ P+LE ++ + PSL+ PN++V TTPP
Sbjct: 754 ENPLLEKPVSEPSTNPPSLEEAPNNWVGTFKTTPP 788
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 30.4 bits (67), Expect = 8.2
Identities = 46/197 (23%), Positives = 80/197 (40%), Gaps = 30/197 (15%)
Query: 376 RKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRA 435
R+ + + EE K+ +E S + I + Q+ R K++I Q +K+Q E+ R
Sbjct: 169 RQTILELEEEKRKHKEYMEKSD-EFICLLEQECERLKKLIDQ--EIKSQEEKEQEKEKRV 225
Query: 436 AKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGL--NAARPDYIASKASPTSTEE 493
+ ++ A++ +Q +T L I L NA + A EE
Sbjct: 226 TTLKEELTKLKSFALMVVDEQQRLTA-QLTLQRQKIQELTTNAKETHTKLALAEARVQEE 284
Query: 494 EQVMLR-------------NDQDTLMARWTGRNSRS----------SLQVDWHEEEWEKV 530
EQ R DQDT+MA+ T +S++ S Q+D EE +
Sbjct: 285 EQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQID-ELEETNRS 343
Query: 531 WLNVDKSLECIIQRVDK 547
++ L+ I +++ K
Sbjct: 344 LRKAEEELQDIKEKISK 360
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 30.4 bits (67), Expect = 8.2
Identities = 46/197 (23%), Positives = 80/197 (40%), Gaps = 30/197 (15%)
Query: 376 RKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRA 435
R+ + + EE K+ +E S + I + Q+ R K++I Q +K+Q E+ R
Sbjct: 169 RQTILELEEEKRKHKEYMEKSD-EFICLLEQECERLKKLIDQ--EIKSQEEKEQEKEKRV 225
Query: 436 AKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGL--NAARPDYIASKASPTSTEE 493
+ ++ A++ +Q +T L I L NA + A EE
Sbjct: 226 TTLKEELTKLKSFALMVVDEQQRLTA-QLTLQRQKIQELTTNAKETHTKLALAEARVQEE 284
Query: 494 EQVMLR-------------NDQDTLMARWTGRNSRS----------SLQVDWHEEEWEKV 530
EQ R DQDT+MA+ T +S++ S Q+D EE +
Sbjct: 285 EQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQID-ELEETNRS 343
Query: 531 WLNVDKSLECIIQRVDK 547
++ L+ I +++ K
Sbjct: 344 LRKAEEELQDIKEKISK 360
>gi|16933559 protocadherin LKC precursor [Homo sapiens]
Length = 1310
Score = 30.4 bits (67), Expect = 8.2
Identities = 25/99 (25%), Positives = 37/99 (37%), Gaps = 10/99 (10%)
Query: 413 EIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIH 472
E +N SY + K+ + A L TR V + D + I
Sbjct: 1033 EATTTLNLFTVDQSYRSRLQFSTPKEEVGANRQAINAALTQATRTTVYIVDIQ----DID 1088
Query: 473 GLNAARPD------YIASKASPTSTEEEQVMLRNDQDTL 505
ARP ++ S + +E VM+RNDQD+L
Sbjct: 1089 SAARARPHSYLDAYFVFPNGSALTLDELSVMIRNDQDSL 1127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,666,888
Number of Sequences: 37866
Number of extensions: 1501178
Number of successful extensions: 3993
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3960
Number of HSP's gapped (non-prelim): 36
length of query: 954
length of database: 18,247,518
effective HSP length: 112
effective length of query: 842
effective length of database: 14,006,526
effective search space: 11793494892
effective search space used: 11793494892
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.