Guide to the Human Genome
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Search of human proteins with 4504431

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504431 high mobility group AT-hook 2 isoform a [Homo
sapiens]
         (109 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504431 high mobility group AT-hook 2 isoform a [Homo sapiens]     224   2e-59
gi|62912482 high mobility group AT-hook 2 isoform b [Homo sapiens]    175   8e-45
gi|22208979 high mobility group AT-hook 1 isoform b [Homo sapiens]     85   1e-17
gi|22208973 high mobility group AT-hook 1 isoform b [Homo sapiens]     85   1e-17
gi|4504433 high mobility group AT-hook 1 isoform b [Homo sapiens]      85   1e-17
gi|22208975 high mobility group AT-hook 1 isoform b [Homo sapiens]     85   1e-17
gi|22208971 high mobility group AT-hook 1 isoform a [Homo sapiens]     83   4e-17
gi|22208967 high mobility group AT-hook 1 isoform a [Homo sapiens]     83   4e-17
gi|239753198 PREDICTED: hypothetical protein [Homo sapiens]            76   5e-15
gi|239747772 PREDICTED: hypothetical protein [Homo sapiens]            76   5e-15
gi|239741638 PREDICTED: hypothetical protein [Homo sapiens]            76   5e-15
gi|155029552 hypothetical protein LOC388115 [Homo sapiens]             45   2e-05
gi|145199237 transcription elongation factor B polypeptide 3 bin...    42   8e-05
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     42   1e-04
gi|209413756 synapsin III isoform IIIg [Homo sapiens]                  42   1e-04
gi|209413752 synapsin III isoform IIIa [Homo sapiens]                  42   1e-04
gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]     41   2e-04
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...    40   3e-04
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo...    40   3e-04
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...    40   3e-04
gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]            40   3e-04
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       40   3e-04
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       40   3e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    40   4e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     40   4e-04
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            40   5e-04
gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3 [...    40   5e-04
gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]            40   5e-04
gi|45580707 heparan sulfate 6-O-sulfotransferase 3 [Homo sapiens]      40   5e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    40   5e-04

>gi|4504431 high mobility group AT-hook 2 isoform a [Homo sapiens]
          Length = 109

 Score =  224 bits (570), Expect = 2e-59
 Identities = 109/109 (100%), Positives = 109/109 (100%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60
           MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP
Sbjct: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60

Query: 61  SKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
           SKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED
Sbjct: 61  SKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109


>gi|62912482 high mobility group AT-hook 2 isoform b [Homo sapiens]
          Length = 106

 Score =  175 bits (443), Expect = 8e-45
 Identities = 85/105 (80%), Positives = 92/105 (87%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60
           MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP
Sbjct: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60

Query: 61  SKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQES 105
           SKAAQKKAEATGEKRPRGRPRKW   + +    ++ +   S++ S
Sbjct: 61  SKAAQKKAEATGEKRPRGRPRKWDNLLPRTSSKKKTSLGNSTKRS 105


>gi|22208979 high mobility group AT-hook 1 isoform b [Homo sapiens]
          Length = 96

 Score = 85.1 bits (209), Expect = 1e-17
 Identities = 51/110 (46%), Positives = 66/110 (60%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQ-QEPTGEPSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +EP+  P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQEKDGT---EKRGRGRPRKQPPKEPSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K   +K   T  ++PRGRP+K           ++E EE  SQES+EE+
Sbjct: 58  AAKT--RKTTTTPGRKPRGRPKK----------LEKEEEEGISQESSEEE 95


>gi|22208973 high mobility group AT-hook 1 isoform b [Homo sapiens]
          Length = 96

 Score = 85.1 bits (209), Expect = 1e-17
 Identities = 51/110 (46%), Positives = 66/110 (60%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQ-QEPTGEPSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +EP+  P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQEKDGT---EKRGRGRPRKQPPKEPSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K   +K   T  ++PRGRP+K           ++E EE  SQES+EE+
Sbjct: 58  AAKT--RKTTTTPGRKPRGRPKK----------LEKEEEEGISQESSEEE 95


>gi|4504433 high mobility group AT-hook 1 isoform b [Homo sapiens]
          Length = 96

 Score = 85.1 bits (209), Expect = 1e-17
 Identities = 51/110 (46%), Positives = 66/110 (60%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQ-QEPTGEPSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +EP+  P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQEKDGT---EKRGRGRPRKQPPKEPSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K   +K   T  ++PRGRP+K           ++E EE  SQES+EE+
Sbjct: 58  AAKT--RKTTTTPGRKPRGRPKK----------LEKEEEEGISQESSEEE 95


>gi|22208975 high mobility group AT-hook 1 isoform b [Homo sapiens]
          Length = 96

 Score = 85.1 bits (209), Expect = 1e-17
 Identities = 51/110 (46%), Positives = 66/110 (60%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQ-QEPTGEPSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +EP+  P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQEKDGT---EKRGRGRPRKQPPKEPSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K   +K   T  ++PRGRP+K           ++E EE  SQES+EE+
Sbjct: 58  AAKT--RKTTTTPGRKPRGRPKK----------LEKEEEEGISQESSEEE 95


>gi|22208971 high mobility group AT-hook 1 isoform a [Homo sapiens]
          Length = 107

 Score = 83.2 bits (204), Expect = 4e-17
 Identities = 52/121 (42%), Positives = 67/121 (55%), Gaps = 27/121 (22%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQ------------QQEPTGEPSPKRP 48
           MS     + QP  S Q +      +KRGRGRPRKQ            Q+EP+  P+PKRP
Sbjct: 1   MSESSSKSSQPLASKQEKDGT---EKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRP 57

Query: 49  RGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEE 108
           RGRPKGSKNK  +K   +K   T  ++PRGRP+K           ++E EE  SQES+EE
Sbjct: 58  RGRPKGSKNKGAAKT--RKTTTTPGRKPRGRPKK----------LEKEEEEGISQESSEE 105

Query: 109 D 109
           +
Sbjct: 106 E 106


>gi|22208967 high mobility group AT-hook 1 isoform a [Homo sapiens]
          Length = 107

 Score = 83.2 bits (204), Expect = 4e-17
 Identities = 52/121 (42%), Positives = 67/121 (55%), Gaps = 27/121 (22%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQ------------QQEPTGEPSPKRP 48
           MS     + QP  S Q +      +KRGRGRPRKQ            Q+EP+  P+PKRP
Sbjct: 1   MSESSSKSSQPLASKQEKDGT---EKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRP 57

Query: 49  RGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEE 108
           RGRPKGSKNK  +K   +K   T  ++PRGRP+K           ++E EE  SQES+EE
Sbjct: 58  RGRPKGSKNKGAAKT--RKTTTTPGRKPRGRPKK----------LEKEEEEGISQESSEE 105

Query: 109 D 109
           +
Sbjct: 106 E 106


>gi|239753198 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 104

 Score = 76.3 bits (186), Expect = 5e-15
 Identities = 48/110 (43%), Positives = 62/110 (56%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGE-PSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +   E P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQKKDGT---EKRGRGRPRKQPPKELSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K    K   T  ++PRGRP+K           ++E E+  SQES+ E+
Sbjct: 58  AAKTG--KTTTTLGRKPRGRPKK----------LEKEEEKGISQESSLEE 95


>gi|239747772 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 104

 Score = 76.3 bits (186), Expect = 5e-15
 Identities = 48/110 (43%), Positives = 62/110 (56%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGE-PSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +   E P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQKKDGT---EKRGRGRPRKQPPKELSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K    K   T  ++PRGRP+K           ++E E+  SQES+ E+
Sbjct: 58  AAKTG--KTTTTLGRKPRGRPKK----------LEKEEEKGISQESSLEE 95


>gi|239741638 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 104

 Score = 76.3 bits (186), Expect = 5e-15
 Identities = 48/110 (43%), Positives = 62/110 (56%), Gaps = 16/110 (14%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGE-PSPKRPRGRPKGSKNKS 59
           MS     + QP  S Q +      +KRGRGRPRKQ  +   E P+PKRPRGRPKGSKNK 
Sbjct: 1   MSESSSKSSQPLASKQKKDGT---EKRGRGRPRKQPPKELSEVPTPKRPRGRPKGSKNKG 57

Query: 60  PSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
            +K    K   T  ++PRGRP+K           ++E E+  SQES+ E+
Sbjct: 58  AAKTG--KTTTTLGRKPRGRPKK----------LEKEEEKGISQESSLEE 95


>gi|155029552 hypothetical protein LOC388115 [Homo sapiens]
          Length = 534

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 10  QPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAE 69
           Q  +  +G+  A A  +RG   PR  Q+    +P P  P G+ +G +   PS A    ++
Sbjct: 274 QDCSQLRGEGPARAGSRRG---PRSHQKL---QPPPLLPDGKGRGGQASRPSVAPATGSK 327

Query: 70  ATGEKRPRGRPRKW----PQQVVQKKPAQEETEETSSQE 104
           A G++R  GR R+W     ++ ++ +   + T ET S+E
Sbjct: 328 ARGKERLTGRARRWDMKEDKEELEGQEGSQSTRETPSEE 366



 Score = 26.2 bits (56), Expect = 6.0
 Identities = 24/98 (24%), Positives = 35/98 (35%), Gaps = 18/98 (18%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGE------------PSPKRP 48
           +S  G G   P  S       P  Q+     P   +Q+P G             P P+R 
Sbjct: 422 LSLGGAGIPGPRESGCVLGLRPGAQESPVSWPEGSKQQPLGWSNHQAELEVQTCPEPQRG 481

Query: 49  RGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQ 86
            G P+  +++S    AQ+         PR RP +   Q
Sbjct: 482 AGLPEPGEDRSGKSGAQQGL------APRSRPTRGGSQ 513


>gi|145199237 transcription elongation factor B polypeptide 3
           binding protein 1 [Homo sapiens]
          Length = 1221

 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 33/134 (24%)

Query: 9   GQPSTSAQGQPAAPA----------PQKRGRGRPRKQQQEPTGEP---SPKRPRGRPKGS 55
           G+P     G P AP+           + +GRGRP ++ +     P   SP+R   RP+G+
Sbjct: 374 GKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPVEKPRADKKGPQASSPRRKAERPEGT 433

Query: 56  KNK-------------SPSKAAQKKAEATGEKRP---RG--RPRKWPQQVVQKKPAQE-- 95
           K K              P + A++ +  +G+ RP   RG  RP + P +   K P+ +  
Sbjct: 434 KKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAGRGPPRPLQLPDRKSTKAPSGKLV 493

Query: 96  ETEETSSQESAEED 109
           E +  S  E A +D
Sbjct: 494 ERKARSLDEGASQD 507



 Score = 27.7 bits (60), Expect = 2.1
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 10/84 (11%)

Query: 8   AGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEP---TGEPSPKRPRGRPK------GSKNK 58
           A +P  + +   +A      G+GRP +  + P   +G+  P   RG P+          K
Sbjct: 427 AERPEGTKKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAGRGPPRPLQLPDRKSTK 486

Query: 59  SPS-KAAQKKAEATGEKRPRGRPR 81
           +PS K  ++KA +  E   +  P+
Sbjct: 487 APSGKLVERKARSLDEGASQDAPK 510


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 23  APQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRK 82
           A + R   R R++++  +G  SPK+PR  PK   ++SPS    KK +   + + R R  +
Sbjct: 333 ARRSRSASRERRRRRSRSGTRSPKKPRS-PKRKLSRSPSPRRHKKEKKKDKDKERSRDER 391

Query: 83  WPQQVVQKKPAQEETEETSSQESAEE 108
                 +KK   +E +     ES ++
Sbjct: 392 ERSTSKKKKSKDKEKDRERKSESDKD 417



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 24/108 (22%), Positives = 47/108 (43%), Gaps = 2/108 (1%)

Query: 3   ARGEGAGQPSTS-AQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPS 61
           +R  G    STS  + +      +KR +  P+          + +  R R   S  +SP 
Sbjct: 297 SRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK 356

Query: 62  KAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
           K    K + +    PR R +K  ++   K+ +++E E ++S++   +D
Sbjct: 357 KPRSPKRKLSRSPSPR-RHKKEKKKDKDKERSRDERERSTSKKKKSKD 403


>gi|209413756 synapsin III isoform IIIg [Homo sapiens]
          Length = 579

 Score = 41.6 bits (96), Expect = 1e-04
 Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 7   GAGQPSTSAQGQPA-APAPQKRGRGRPRKQQQEPTGE---------PSPKRPRGRP---K 53
           G  QP    QG P  A +PQ +  G P +Q+  P G+         P  +R  G P   +
Sbjct: 429 GQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSR 488

Query: 54  GSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQ-KKPAQEETEETSSQ 103
            S   SP++A++  A    + RP  + R   QQ  + KKPA        SQ
Sbjct: 489 ASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 539



 Score = 28.9 bits (63), Expect = 0.93
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 9/80 (11%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60
           +S    G+     S  G   A  P+   +GR   QQ E + +P+P  P        NKS 
Sbjct: 486 LSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPH------LNKSQ 539

Query: 61  SKAAQKKAEATGEKRPRGRP 80
           S      + +T +   RG P
Sbjct: 540 SLT---NSLSTSDTSQRGTP 556


>gi|209413752 synapsin III isoform IIIa [Homo sapiens]
          Length = 580

 Score = 41.6 bits (96), Expect = 1e-04
 Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 7   GAGQPSTSAQGQPA-APAPQKRGRGRPRKQQQEPTGE---------PSPKRPRGRP---K 53
           G  QP    QG P  A +PQ +  G P +Q+  P G+         P  +R  G P   +
Sbjct: 430 GQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSR 489

Query: 54  GSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQ-KKPAQEETEETSSQ 103
            S   SP++A++  A    + RP  + R   QQ  + KKPA        SQ
Sbjct: 490 ASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 540



 Score = 28.9 bits (63), Expect = 0.93
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 9/80 (11%)

Query: 1   MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60
           +S    G+     S  G   A  P+   +GR   QQ E + +P+P  P        NKS 
Sbjct: 487 LSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPH------LNKSQ 540

Query: 61  SKAAQKKAEATGEKRPRGRP 80
           S      + +T +   RG P
Sbjct: 541 SLT---NSLSTSDTSQRGTP 557


>gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]
          Length = 1537

 Score = 40.8 bits (94), Expect = 2e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 17/93 (18%)

Query: 8   AGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKK 67
           A  P+   +G+ A PA      G     ++E  G  + K+P          SPSKA +KK
Sbjct: 353 AATPTKGPEGKVAGPADAPMDSGA----EEEKAGAATVKKP----------SPSKARKKK 398

Query: 68  AEATGEK---RPRGRPRKWPQQVVQKKPAQEET 97
               G K   R RGRP+K      ++KP + +T
Sbjct: 399 LNKKGRKMAGRKRGRPKKMNTANPERKPKKNQT 431



 Score = 27.7 bits (60), Expect = 2.1
 Identities = 16/63 (25%), Positives = 26/63 (41%)

Query: 8   AGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKK 67
           A   S + + +  A   +K    + RK++    G     R RGRPK     +P +  +K 
Sbjct: 370 APMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKN 429

Query: 68  AEA 70
             A
Sbjct: 430 QTA 432


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 6/99 (6%)

Query: 16  QGQPAAPA---PQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATG 72
           +G+PAA     P+ RGR +  KQ      +   +  + + KG + K P K  +K  E   
Sbjct: 180 RGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQK 239

Query: 73  EK-RPRGRP--RKWPQQVVQKKPAQEETEETSSQESAEE 108
           E+ +PR  P  ++  ++V  K+    +T  TS+ +S EE
Sbjct: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEE 278



 Score = 28.9 bits (63), Expect = 0.93
 Identities = 23/111 (20%), Positives = 42/111 (37%), Gaps = 12/111 (10%)

Query: 9   GQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKA 68
           GQ     + QP      ++   +PRK+  +  G+   +  R     +   S S + ++  
Sbjct: 221 GQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGD 280

Query: 69  EATGEKRPRGRPR------------KWPQQVVQKKPAQEETEETSSQESAE 107
           +  GEK+ +G               +  ++   +K  QEE  ET  Q   E
Sbjct: 281 DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDE 331


>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 6/99 (6%)

Query: 16  QGQPAAPA---PQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATG 72
           +G+PAA     P+ RGR +  KQ      +   +  + + KG + K P K  +K  E   
Sbjct: 180 RGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQK 239

Query: 73  EK-RPRGRP--RKWPQQVVQKKPAQEETEETSSQESAEE 108
           E+ +PR  P  ++  ++V  K+    +T  TS+ +S EE
Sbjct: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEE 278



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/107 (20%), Positives = 41/107 (38%), Gaps = 12/107 (11%)

Query: 9   GQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKA 68
           GQ     + QP      ++   +PRK+  +  G+   +  R     +   S S + ++  
Sbjct: 221 GQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGD 280

Query: 69  EATGEKRPRGRPR------------KWPQQVVQKKPAQEETEETSSQ 103
           +  GEK+ +G               +  ++   +K  QEE  ET  Q
Sbjct: 281 DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 6/99 (6%)

Query: 16  QGQPAAPA---PQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATG 72
           +G+PAA     P+ RGR +  KQ      +   +  + + KG + K P K  +K  E   
Sbjct: 180 RGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQK 239

Query: 73  EK-RPRGRP--RKWPQQVVQKKPAQEETEETSSQESAEE 108
           E+ +PR  P  ++  ++V  K+    +T  TS+ +S EE
Sbjct: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEE 278



 Score = 28.9 bits (63), Expect = 0.93
 Identities = 23/111 (20%), Positives = 42/111 (37%), Gaps = 12/111 (10%)

Query: 9   GQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKA 68
           GQ     + QP      ++   +PRK+  +  G+   +  R     +   S S + ++  
Sbjct: 221 GQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGD 280

Query: 69  EATGEKRPRGRPR------------KWPQQVVQKKPAQEETEETSSQESAE 107
           +  GEK+ +G               +  ++   +K  QEE  ET  Q   E
Sbjct: 281 DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDE 331


>gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 381

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 10/82 (12%)

Query: 3   ARGEGAGQPSTSAQGQPAA-----PAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKN 57
           +RG G    +T  Q  PAA     P P +R RG PR    EP   P P     RP  +  
Sbjct: 273 SRGSGRAATTTRPQTTPAAASPDLPQPAERSRGEPR--PAEPRAPPRPPPAARRPPPATA 330

Query: 58  KSPSKAAQKKAEATGEKRPRGR 79
            SP +A    +  T E+ PR R
Sbjct: 331 PSPRRAG---SPPTREEEPRPR 349



 Score = 33.1 bits (74), Expect = 0.049
 Identities = 15/57 (26%), Positives = 27/57 (47%)

Query: 10  QPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQK 66
           QP+  ++G+P    P+   R  P  ++  P   PSP+R    P   +   P ++A +
Sbjct: 298 QPAERSRGEPRPAEPRAPPRPPPAARRPPPATAPSPRRAGSPPTREEEPRPRRSAAR 354



 Score = 30.0 bits (66), Expect = 0.42
 Identities = 14/40 (35%), Positives = 21/40 (52%)

Query: 10  QPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPR 49
           +P  +A+  P A AP  R  G P  +++EP    S  RP+
Sbjct: 317 RPPPAARRPPPATAPSPRRAGSPPTREEEPRPRRSAARPQ 356


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 25/128 (19%)

Query: 1   MSARGEGAGQP-------STSAQGQPAAPA-PQKRGRGRPRK---------QQQEPTGEP 43
           +S  G  AG P        TSA  QPA+ A P  +G+GR  +             P   P
Sbjct: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552

Query: 44  SPKRPRGRPKGSKNKSPSKAAQKKAEAT--GEKRPRGRPRKWP------QQVVQKKPAQE 95
           SP+R  G P+ ++  S S  A  KA     G ++ +G P+K P      +Q  Q  P   
Sbjct: 553 SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612

Query: 96  ETEETSSQ 103
               T+ Q
Sbjct: 613 TGPPTTQQ 620



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 3   ARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNK-SPS 61
           +R    G  +  A   PA+P+PQ++  G P+  +Q     P+P +  G P G + +  P 
Sbjct: 533 SRPVAGGPGAPPAARPPASPSPQRQA-GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591

Query: 62  KAAQKKAEATGEKRPRGR-PRKWPQQVVQKKPA 93
           +     A  T +    G  PR  P    Q +P+
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS 624



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 7/79 (8%)

Query: 8   AGQPSTSA---QGQPAAPAPQKRGRGRPRKQQQEPTGEPSPK---RPRGRPKGSKNKSPS 61
           AG P+      QG P  P P  + +G P +Q+  P G+        P G P   +  SP+
Sbjct: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512

Query: 62  KAAQKKA-EATGEKRPRGR 79
            A Q+ A +A    + +GR
Sbjct: 513 SAPQQPASQAAPPTQGQGR 531



 Score = 29.6 bits (65), Expect = 0.54
 Identities = 22/74 (29%), Positives = 28/74 (37%), Gaps = 7/74 (9%)

Query: 9   GQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKA 68
           G    + Q   A P P+    G P  QQ  P+G      P GRPK    + PS+     A
Sbjct: 596 GPAGPTRQASQAGPVPRT---GPPTTQQPRPSGPG----PAGRPKPQLAQKPSQDVPPPA 648

Query: 69  EATGEKRPRGRPRK 82
            A     P  +  K
Sbjct: 649 TAAAGGPPHPQLNK 662



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 23/102 (22%), Positives = 36/102 (35%), Gaps = 9/102 (8%)

Query: 11  PSTSAQGQPAAPAPQKRGR-------GRPRKQQQEPTGEPSPKRPRGRPKGSK-NKSPSK 62
           P   + GQ  +P     GR       G P +Q+  P G P    P  + +G    + P  
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487

Query: 63  AAQKKAEATGEKRPRGRPRKWPQQV-VQKKPAQEETEETSSQ 103
             Q+     G       P++ P      ++PA +    T  Q
Sbjct: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/51 (27%), Positives = 23/51 (45%)

Query: 11  PSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPS 61
           P T+ Q +P+ P P  R + +  ++  +    P+     G P    NKS S
Sbjct: 615 PPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQS 665


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 25/128 (19%)

Query: 1   MSARGEGAGQP-------STSAQGQPAAPA-PQKRGRGRPRK---------QQQEPTGEP 43
           +S  G  AG P        TSA  QPA+ A P  +G+GR  +             P   P
Sbjct: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552

Query: 44  SPKRPRGRPKGSKNKSPSKAAQKKAEAT--GEKRPRGRPRKWP------QQVVQKKPAQE 95
           SP+R  G P+ ++  S S  A  KA     G ++ +G P+K P      +Q  Q  P   
Sbjct: 553 SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612

Query: 96  ETEETSSQ 103
               T+ Q
Sbjct: 613 TGPPTTQQ 620



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 3   ARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNK-SPS 61
           +R    G  +  A   PA+P+PQ++  G P+  +Q     P+P +  G P G + +  P 
Sbjct: 533 SRPVAGGPGAPPAARPPASPSPQRQA-GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591

Query: 62  KAAQKKAEATGEKRPRGR-PRKWPQQVVQKKPA 93
           +     A  T +    G  PR  P    Q +P+
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS 624



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 7/79 (8%)

Query: 8   AGQPSTSA---QGQPAAPAPQKRGRGRPRKQQQEPTGEPSPK---RPRGRPKGSKNKSPS 61
           AG P+      QG P  P P  + +G P +Q+  P G+        P G P   +  SP+
Sbjct: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512

Query: 62  KAAQKKA-EATGEKRPRGR 79
            A Q+ A +A    + +GR
Sbjct: 513 SAPQQPASQAAPPTQGQGR 531



 Score = 31.2 bits (69), Expect = 0.19
 Identities = 23/78 (29%), Positives = 30/78 (38%), Gaps = 7/78 (8%)

Query: 9   GQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKA 68
           G    + Q   A P P+    G P  QQ  P+G      P GRPK    + PS+     A
Sbjct: 596 GPAGPTRQASQAGPVPRT---GPPTTQQPRPSGPG----PAGRPKPQLAQKPSQDVPPPA 648

Query: 69  EATGEKRPRGRPRKWPQQ 86
            A     P  + +  P Q
Sbjct: 649 TAAAGGPPHPQLKASPAQ 666



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 23/102 (22%), Positives = 36/102 (35%), Gaps = 9/102 (8%)

Query: 11  PSTSAQGQPAAPAPQKRGR-------GRPRKQQQEPTGEPSPKRPRGRPKGSK-NKSPSK 62
           P   + GQ  +P     GR       G P +Q+  P G P    P  + +G    + P  
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487

Query: 63  AAQKKAEATGEKRPRGRPRKWPQQV-VQKKPAQEETEETSSQ 103
             Q+     G       P++ P      ++PA +    T  Q
Sbjct: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529



 Score = 26.6 bits (57), Expect = 4.6
 Identities = 13/53 (24%), Positives = 24/53 (45%)

Query: 11  PSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKA 63
           P T+ Q +P+ P P  R + +  ++  +    P+     G P      SP++A
Sbjct: 615 PPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQA 667


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
          potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 1  MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP 60
          M ARG G G+P  S     A PAP       P   QQ+P   P P  P G P  +  + P
Sbjct: 1  MDARG-GGGRPGESPG---ATPAPGPPPPPPPAPPQQQPPPPPPPAPPPG-PGPAPPQHP 55

Query: 61 SKAAQKKAEATGEKRPRGRPR 81
           +A     EA  E  PRGR R
Sbjct: 56 PRAEALPPEAADEGGPRGRLR 76



 Score = 27.7 bits (60), Expect = 2.1
 Identities = 22/87 (25%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 14  SAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQK------- 66
           S+ G+P  P      +G P  +      + SP  P G  +G K     + A         
Sbjct: 80  SSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPG 139

Query: 67  KAEATG--EKRPRGRPRKWPQQVVQKK 91
            AE  G  E  P G PR      +Q++
Sbjct: 140 PAEEAGSEEAGPAGEPRGSQASFMQRQ 166


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 9/94 (9%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRG-RPKGSKNKSP 60
           S  G+  G P          P P  + +G P +   +P G P P +P+G  P+G K++SP
Sbjct: 52  SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 111

Query: 61  SKAAQKKA--------EATGEKRPRGRPRKWPQQ 86
                K          +  G   P G+P+  P Q
Sbjct: 112 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 10/95 (10%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPS 61
           S  G+  G P          P P  + +G P +   +P G P P +P+G P    NKS S
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS 172

Query: 62  KAA----------QKKAEATGEKRPRGRPRKWPQQ 86
             +          Q   +  G   P G+P+  P Q
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 10/95 (10%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPS 61
           S  G+  G P          P P  + +G P +   +P G P P +P+G P    NKS S
Sbjct: 175 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234

Query: 62  KAA----------QKKAEATGEKRPRGRPRKWPQQ 86
             +          Q   +  G   P G+P+  P Q
Sbjct: 235 ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269



 Score = 38.5 bits (88), Expect = 0.001
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 11/85 (12%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPS 61
           S  G+  G P          P P  + +G P +   +P G P P +P+G P    +KS S
Sbjct: 299 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 358

Query: 62  KAAQKKAEATGEKRPRGRPRKWPQQ 86
                       + P G+P+  PQQ
Sbjct: 359 -----------ARSPPGKPQGPPQQ 372



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 22/105 (20%)

Query: 4   RGEGAGQPSTSAQGQPAAPAPQK------------RGRGRPRKQQQEPTGEPSPKRPRGR 51
           +G+   Q + S  G+P  P PQ             + +G P +   +P G P P +P+G 
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 286

Query: 52  PK--GSKNKS----PSK----AAQKKAEATGEKRPRGRPRKWPQQ 86
           P   GSK++S    P K      Q   +  G   P G+P+  P Q
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 11/89 (12%)

Query: 4   RGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPS------PKRPRGRPKGSKN 57
           +G+   + S S  G+P  P PQ    G   +    P G+P         +P+G P   K 
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQG---GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 221

Query: 58  KSPSKAAQKKAEATGEKRPRGRPRKWPQQ 86
           + P      K+++   + P G+P+  P Q
Sbjct: 222 QGPPPQGDNKSQSA--RSPPGKPQGPPPQ 248



 Score = 33.5 bits (75), Expect = 0.038
 Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 5   GEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPK-RPRGRPKGSKNK----- 58
           G   G P          P+P  + +G P +   +P G P P  +P+G P    NK     
Sbjct: 34  GNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 93

Query: 59  SPSKAAQKKAEATGEKRPRGRPRK 82
            P K      +    + PR  P K
Sbjct: 94  PPGKPQGPPPQGDKSRSPRSPPGK 117



 Score = 32.7 bits (73), Expect = 0.064
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 7/77 (9%)

Query: 6   EGAGQPS--TSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKA 63
           +G  QP       G+P  P PQ    G  + Q   P G+P    P+G  K    +SP   
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQ----GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK 365

Query: 64  AQKKAEATGEKRPRGRP 80
            Q   +  G   P+G P
Sbjct: 366 PQGPPQQEG-NNPQGPP 381



 Score = 32.3 bits (72), Expect = 0.084
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 10/92 (10%)

Query: 5   GEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPK-RPRGRPKGSKNK----- 58
           G+  G P        +A +P  + +G P +   +P G P P  +P+G P    NK     
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278

Query: 59  SPSK----AAQKKAEATGEKRPRGRPRKWPQQ 86
            P K      Q  +++   + P G+P+  P Q
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 5/74 (6%)

Query: 17  GQPAAPAPQKRGRGRP-RKQQQEPTGEPSPK--RPRGRPKGSKNKSPSKAAQKKAEATGE 73
           G+P  P PQ   + R  R    +P G P  +   P+G P  +        A    +  G 
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402

Query: 74  KRPR--GRPRKWPQ 85
            RP   GRP + PQ
Sbjct: 403 PRPPQGGRPSRPPQ 416



 Score = 29.6 bits (65), Expect = 0.54
 Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 25/93 (26%)

Query: 17  GQPAAPAPQ----KRGRGRPRKQQ-------QEPTGEPSP------------KRPRGRPK 53
           G+P  P PQ    +  R  P K Q        +P G P P             +P+G P 
Sbjct: 96  GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 155

Query: 54  GSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQ 86
             K + P      K+ ++  + P G+P+  P Q
Sbjct: 156 PGKPQGPPPQGDNKSRSS--RSPPGKPQGPPPQ 186



 Score = 29.6 bits (65), Expect = 0.54
 Identities = 15/61 (24%), Positives = 27/61 (44%), Gaps = 5/61 (8%)

Query: 5   GEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEP-----SPKRPRGRPKGSKNKS 59
           G+  G P        +A +P  + +G P+++   P G P     +P++P+  P G     
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402

Query: 60  P 60
           P
Sbjct: 403 P 403



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 25/102 (24%), Positives = 39/102 (38%), Gaps = 14/102 (13%)

Query: 6   EGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEP--------TGEPSPKRPRGRPKGSKN 57
           +G   P    QG P     + +G   P K Q  P        +    P +P+G P+   N
Sbjct: 316 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375

Query: 58  K-----SPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQ 94
                  P+    ++ +A    +P+G PR  PQ     +P Q
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQGGRPSRPPQ 416


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 4   RGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKA 63
           +   AG  S     +      ++RG GR + + Q P    + K P  +P+G  +K P + 
Sbjct: 372 KASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRR-AQKAPAAKPRGGGSKKPRRR 430

Query: 64  AQKKAEATGEKRPRG---RPRKWPQQVVQK 90
             K A++ G K   G   +PR+  Q+  QK
Sbjct: 431 GPKAAKSRGGKSRSGGGKKPRRRGQKARQK 460



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 13/105 (12%)

Query: 9   GQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKA 68
           GQ + +A  +  A   + RGR +PR+Q      +P+    + R  GSK++   KA    A
Sbjct: 503 GQKAEAAGEKATAAGAKSRGRKQPRRQ------KPAVAGAKSRVGGSKSRQRQKAVAAGA 556

Query: 69  EA---TGEKRPRG----RPRKWPQQVVQKKPAQEETEETSSQESA 106
            +    G K+ RG    +PR+W Q     K      ++   Q++A
Sbjct: 557 TSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAA 601



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 10/114 (8%)

Query: 4   RGEGAGQPSTSAQGQPAAPAPQKR---GRGRPRKQQQEPTGEPSPKRPRGRPK-----GS 55
           +  GAG       G+  A A   +   GRGR  +++ +       K+PR R +     GS
Sbjct: 91  KAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGS 150

Query: 56  KNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED 109
           KN+     AQK A A G K   G   +       K  + ++     ++   +ED
Sbjct: 151 KNRGAG--AQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDED 202



 Score = 33.1 bits (74), Expect = 0.049
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 4   RGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSP--KRPRGRPKGSKNKSPS 61
           +   AG  +  A  Q AA A   + +G  + Q+    G  S   K+PR R   S+     
Sbjct: 144 KSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDK 203

Query: 62  KAAQKKAEATGEKRPRGRPRK 82
           K  Q++A++   K   GR +K
Sbjct: 204 KGRQREAKSRFGKTRGGRRKK 224



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 4   RGEGAGQPSTSAQGQPA--APAPQKRGRG--RPRKQQQEPTGEPSPKRPRG---RPKGSK 56
           RG+G  +P      + A  APA + RG G  +PR++  +       K   G   +P+   
Sbjct: 395 RGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRG 454

Query: 57  NKSPSKAAQKKAEATGEKRPRGRPR 81
            K+  KAA+  AE+ G+K+ +GR +
Sbjct: 455 QKARQKAAEAGAESRGDKK-QGRQK 478



 Score = 30.0 bits (66), Expect = 0.42
 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 3   ARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRP-RGRPKGSKNKSPS 61
           A   G+ +P   AQ + AA   + RG G  +            ++P +    G+K++S  
Sbjct: 130 AAATGSKKPRWRAQ-KSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGK 188

Query: 62  KAAQKKAEATGEKRPRGRPRK 82
           K  ++ A++ G++  +GR R+
Sbjct: 189 KPRRRGAKSRGDEDKKGRQRE 209



 Score = 26.6 bits (57), Expect = 4.6
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 5   GEGAGQPSTSAQGQPAAPAPQKRG-RGRPRKQQQEPTGEPSP----KRPRGRPKGSKNKS 59
           G+ A +   +  G  +   P +RG +     ++   TG  S     K+PR +   +    
Sbjct: 613 GKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSE 672

Query: 60  PSKAAQKKAEATGEKRPRGRPRK 82
            S AA    EA   K+PR R  K
Sbjct: 673 SSAAAAVGQEAEARKKPRRRRAK 695


>gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3
           [Homo sapiens]
          Length = 471

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 12/92 (13%)

Query: 10  QPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAE 69
           QP     G PA P P +R +  P + ++ P   P P+ P   P+G+            A 
Sbjct: 40  QPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGA------------AA 87

Query: 70  ATGEKRPRGRPRKWPQQVVQKKPAQEETEETS 101
              E    G PR+  ++  + +P  E  E  S
Sbjct: 88  PEEEDEEPGDPREGEEEEEEDEPDPEAPENGS 119


>gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 33/108 (30%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 6   EGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAA- 64
           EGA  P  +  G  AAP P    RG      + P+    P         S  ++P   A 
Sbjct: 71  EGARGPRAARGGARAAPMPSSAPRGPTEPALRRPSSAERPLAQAPSSSASVGRAPGAMAS 130

Query: 65  -QKKAEATGEKRPR-GRPRKWPQQV-VQKKPAQEETEETSSQESAEED 109
             + +EATG+ R R GRPR+    V  ++K  +   E  S+Q    ED
Sbjct: 131 PSRSSEATGKPRGRDGRPRREEDDVPPEEKRLRLLLEGGSAQPQDGED 178


>gi|45580707 heparan sulfate 6-O-sulfotransferase 3 [Homo sapiens]
          Length = 471

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 12/92 (13%)

Query: 10  QPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAE 69
           QP     G PA P P +R +  P + ++ P   P P+ P   P+G+            A 
Sbjct: 40  QPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGA------------AA 87

Query: 70  ATGEKRPRGRPRKWPQQVVQKKPAQEETEETS 101
              E    G PR+  ++  + +P  E  E  S
Sbjct: 88  PEEEDEEPGDPREGEEEEEEDEPDPEAPENGS 119


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 9/94 (9%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRG-RPKGSKNKSP 60
           S  G+  G P          P P  + +G P +    P G P P +P+G  P+G K++SP
Sbjct: 92  SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151

Query: 61  SKAAQKKA--------EATGEKRPRGRPRKWPQQ 86
                K          +  G   P G+P+  P Q
Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 11/85 (12%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPS 61
           S  G+  G P          P P  + +G P +   +P G P P +P+G P    +KS S
Sbjct: 214 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQS 273

Query: 62  KAAQKKAEATGEKRPRGRPRKWPQQ 86
                       + P G+P+  PQQ
Sbjct: 274 -----------ARSPPGKPQGPPQQ 287



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 9/94 (9%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRG-RPKGSKNKS- 59
           S  G+  G P          P P  + +G P +  ++P G P P +P+G  P+G K++S 
Sbjct: 153 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS 212

Query: 60  ---PSK----AAQKKAEATGEKRPRGRPRKWPQQ 86
              P K      Q   +  G   P G+P+  P Q
Sbjct: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246



 Score = 33.9 bits (76), Expect = 0.029
 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 18/94 (19%)

Query: 2   SARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRG-RPKGSKNKSP 60
           S +G    Q      G+P  P PQ   +         P G P P +P+G  P+G K++SP
Sbjct: 40  SPQGGNKPQGPPPPPGKPQGPPPQGGNK---------PQGPPPPGKPQGPPPQGDKSRSP 90

Query: 61  SKAAQKKA--------EATGEKRPRGRPRKWPQQ 86
                K          +  G   P G+P+  P Q
Sbjct: 91  RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 124



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 11/83 (13%)

Query: 5   GEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAA 64
           G+  G P+       +A +P  + +G P+++   P G P P        G   + P   A
Sbjct: 258 GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA-------GGNPQQPQ--A 308

Query: 65  QKKAEATGEKRPR--GRPRKWPQ 85
               +  G  RP   GRP + PQ
Sbjct: 309 PPAGQPQGPPRPPQGGRPSRPPQ 331



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 16/73 (21%)

Query: 3   ARGEGAGQPSTSAQGQPAAPAPQKRGR----------GRPRKQQQEPTGEPSPKRPRGRP 52
           A+G    Q + S  G+P  P PQ+ G           G P++ Q  P G+P     +G P
Sbjct: 265 AQGGSKSQSARSPPGKPQGP-PQQEGNNPQGPPPPAGGNPQQPQAPPAGQP-----QGPP 318

Query: 53  KGSKNKSPSKAAQ 65
           +  +   PS+  Q
Sbjct: 319 RPPQGGRPSRPPQ 331



 Score = 29.6 bits (65), Expect = 0.54
 Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 26/93 (27%)

Query: 17  GQPAAPAPQ----KRGRGRPRKQQ-------QEPTGEPSP------------KRPRGRPK 53
           G+P  P PQ    +  R  P K Q        +P G P P            K+P+G P 
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP 195

Query: 54  GSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQ 86
             K + P     K   +   + P G+P+  P Q
Sbjct: 196 PGKPQGPPPQGDK---SRSSQSPPGKPQGPPPQ 225



 Score = 28.9 bits (63), Expect = 0.93
 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 26/93 (27%)

Query: 17  GQPAAPAPQ----KRGRGRPRKQQ-------QEPTGEPSP------------KRPRGRPK 53
           G+P  P PQ    +  R  P K Q        +P G P P             RP+G P 
Sbjct: 75  GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134

Query: 54  GSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQ 86
             K + P     K   +   + P G+P+  P Q
Sbjct: 135 PGKPQGPPPQGDK---SRSPRSPPGKPQGPPPQ 164



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 13/71 (18%)

Query: 17 GQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNK-----SPSKAAQKKAEAT 71
          G P  P+PQ  G  +P    Q P   P P +P+G P    NK      P K      +  
Sbjct: 34 GNPQGPSPQ--GGNKP----QGPP--PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85

Query: 72 GEKRPRGRPRK 82
            + PR  P K
Sbjct: 86 KSRSPRSPPGK 96


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.298    0.118    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,665,191
Number of Sequences: 37866
Number of extensions: 403983
Number of successful extensions: 6497
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 552
Number of HSP's successfully gapped in prelim test: 869
Number of HSP's that attempted gapping in prelim test: 3643
Number of HSP's gapped (non-prelim): 3150
length of query: 109
length of database: 18,247,518
effective HSP length: 79
effective length of query: 30
effective length of database: 15,256,104
effective search space: 457683120
effective search space used: 457683120
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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