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Search of human proteins with 4504205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504205 general transcription factor IIIC, polypeptide 2,
beta 110kDa [Homo sapiens]
(911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|78482617 general transcription factor IIIC, polypeptide 2, be... 1893 0.0
gi|4504205 general transcription factor IIIC, polypeptide 2, bet... 1893 0.0
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 51 6e-06
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 48 5e-05
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 47 8e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 8e-05
gi|148727255 microtubule associated serine/threonine kinase fami... 46 1e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 45 2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 45 2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 2e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 45 3e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 45 3e-04
gi|119943102 CREB binding protein isoform b [Homo sapiens] 45 4e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens] 45 4e-04
gi|4507703 tumor suppressing subtransferable candidate 1 [Homo s... 45 4e-04
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 44 5e-04
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 44 7e-04
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 43 0.001
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 43 0.001
gi|210032580 SET domain containing 1B [Homo sapiens] 43 0.001
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 43 0.002
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 43 0.002
gi|91208420 bassoon protein [Homo sapiens] 42 0.002
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 42 0.003
gi|118402582 cell division cycle 20 [Homo sapiens] 42 0.003
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 42 0.003
gi|164419758 bromodomain containing 2 [Homo sapiens] 42 0.003
gi|4826806 bromodomain containing 2 [Homo sapiens] 42 0.003
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 42 0.003
>gi|78482617 general transcription factor IIIC, polypeptide 2, beta
110kDa [Homo sapiens]
Length = 911
Score = 1893 bits (4904), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60
MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF
Sbjct: 1 MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60
Query: 61 EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120
EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP
Sbjct: 61 EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120
Query: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180
SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG
Sbjct: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180
Query: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240
ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD
Sbjct: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240
Query: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP
Sbjct: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
Query: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360
NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV
Sbjct: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360
Query: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420
QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS
Sbjct: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420
Query: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480
PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA
Sbjct: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480
Query: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540
WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT
Sbjct: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540
Query: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600
LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS
Sbjct: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600
Query: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660
LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE
Sbjct: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660
Query: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720
LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI
Sbjct: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720
Query: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780
AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN
Sbjct: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780
Query: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840
PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV
Sbjct: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840
Query: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900
RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF
Sbjct: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900
Query: 901 SPTSHRLLPTP 911
SPTSHRLLPTP
Sbjct: 901 SPTSHRLLPTP 911
>gi|4504205 general transcription factor IIIC, polypeptide 2, beta
110kDa [Homo sapiens]
Length = 911
Score = 1893 bits (4904), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60
MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF
Sbjct: 1 MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60
Query: 61 EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120
EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP
Sbjct: 61 EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120
Query: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180
SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG
Sbjct: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180
Query: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240
ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD
Sbjct: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240
Query: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP
Sbjct: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
Query: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360
NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV
Sbjct: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360
Query: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420
QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS
Sbjct: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420
Query: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480
PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA
Sbjct: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480
Query: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540
WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT
Sbjct: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540
Query: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600
LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS
Sbjct: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600
Query: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660
LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE
Sbjct: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660
Query: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720
LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI
Sbjct: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720
Query: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780
AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN
Sbjct: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780
Query: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840
PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV
Sbjct: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840
Query: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900
RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF
Sbjct: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900
Query: 901 SPTSHRLLPTP 911
SPTSHRLLPTP
Sbjct: 901 SPTSHRLLPTP 911
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 50.8 bits (120), Expect = 6e-06
Identities = 88/343 (25%), Positives = 124/343 (36%), Gaps = 65/343 (18%)
Query: 58 PGFEDSPDQRRLPPEQESLSRLEQPDLSS-----EMSKVSKPRASKPGRKRGGRTRKGP- 111
P FE+SP L P E L P+ S E S +S P P +R P
Sbjct: 547 PPFEESP----LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 112 --KRPQQPNPPSAPLVP-------GLLDQSNPLSTPMPKKRGRKSKAE---LLLLKLSKD 159
+ P P P +PL P + +P+S P P++ E L L +
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSR 661
Query: 160 LDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALP---APVSCP--- 213
L P +SP PP + E+P+ P L E+ T+ P +P S P
Sbjct: 662 LSPPPEESPLSPPPE-ESPTSPPPEASR-------LSPPPEDSPTSPPPEDSPASPPPED 713
Query: 214 --------EGPKVSSPTKPK---KIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEG 262
E P + P +P+ + P P EE +PR E+ L +AE+ S
Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773
Query: 263 PSESSSEPEPVVPRSTPRGSTSG-KQKPHCRGMAPNGLPNHIM-APVWKCL-------HL 313
P E P P +P+ +P ++P H+ P CL HL
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833
Query: 314 TKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSP 356
+ E S P + HL ELE P P+ EK P
Sbjct: 834 SPQSEEPCLS--------PRPEESHLSPELEKPPLSPRPEKPP 868
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/269 (26%), Positives = 92/269 (34%), Gaps = 30/269 (11%)
Query: 13 EAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSP--DQRRLP 70
EA P+G V P QL+ + EM E L P SP + RL
Sbjct: 415 EAKPLGKAGVQLEP------QLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLS 468
Query: 71 PEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLD 130
P E L P E +S+P P + + P P P S+P P L+
Sbjct: 469 PPPEELPASPLP----EALHLSRPLEESP------LSPPPEESPLSPPPESSPFSP--LE 516
Query: 131 QSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQV 190
+S PLS P + L + L P +SP PP + E P+ P
Sbjct: 517 ES-PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE-ELPTSPPPEASR--- 571
Query: 191 ALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFL 250
L EE S P P P P + + P EE +P E L
Sbjct: 572 ----LSPPPEE-SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
Query: 251 QVEAEDVEESEGPSESSSEPEPVVPRSTP 279
ED S P ES P P V R +P
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSP 655
Score = 45.1 bits (105), Expect = 3e-04
Identities = 74/283 (26%), Positives = 105/283 (37%), Gaps = 45/283 (15%)
Query: 39 SSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
+S ++ MS P P+ RL P +SRL P E S +S P
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP-LPVVSRLSPPP---EESPLSPPPEES 678
Query: 99 PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
P +R P P + +P S P + +P S P E LL L +
Sbjct: 679 PTSPPPEASRLSP--PPEDSPTSPP------PEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 159 DLDR-PESQSPK---RPPEDFETPSGERPRRRAAQVALLYLQELAEE--LSTALPAPVSC 212
+ P S+ P RP E +P E P +L AEE LS P C
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEP----------HLSPQAEEPHLSPQPEEPCLC 780
Query: 213 --PEGPKVSSPTK-------PKKIR------QPAACPGGEEVDGAPRDEDFFLQVEAEDV 257
PE P +S + P+++ +P P EE +P+ E+ L ++E+
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 258 EESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
S P ES PE P +PR ++ C AP LP
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC--PAPEELP 881
Score = 36.2 bits (82), Expect = 0.14
Identities = 60/258 (23%), Positives = 87/258 (33%), Gaps = 28/258 (10%)
Query: 48 SVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGR------ 101
S E+ P P E P++ P E L P S + +P S+PG
Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911
Query: 102 ------KRGGRTRKGPK--RPQQPNPPSAPLV----PGLLDQSNPLSTPMPKKRGRKSKA 149
G P+ P PP +P++ P L L P K ++
Sbjct: 912 PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPES 971
Query: 150 ELLLLKLSKDLDRPESQS---PKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTAL 206
L L + P + P+ P PS P A+ + + L L
Sbjct: 972 PLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031
Query: 207 PAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSES 266
P + P + S P P + P + P G+ V DE ++E E V E E P
Sbjct: 1032 LVPQNSPPS-QCSPPALPLSVPSPLS-PIGKVV--GVSDEAELHEMETEKVSEPECP--- 1084
Query: 267 SSEPEPVVPRSTPRGSTS 284
+ EP P +P G S
Sbjct: 1085 ALEPSATSPLPSPMGDLS 1102
Score = 33.9 bits (76), Expect = 0.71
Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 4/106 (3%)
Query: 34 LDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSK 93
LD+ + L TP + +++ LP Q+ + PD++ E S+ +
Sbjct: 1782 LDLSRKALFAVGVGRPSFGLGTPKAKGDGGSERKELPTSQKGD---DGPDIADEESRGLE 1838
Query: 94 PRASKPGRKRGG-RTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTP 138
+A PG + GG + P P++P P ++ LD+ + P
Sbjct: 1839 GKADTPGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRISTEELP 1884
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 47.8 bits (112), Expect = 5e-05
Identities = 53/198 (26%), Positives = 80/198 (40%), Gaps = 32/198 (16%)
Query: 16 PVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMS-----LPTPLPGF--EDSPDQRR 68
PV +MT V P +++ D S E + + P GF +D P
Sbjct: 566 PVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGG-- 623
Query: 69 LPPEQESLSRLEQPDLSSEMSKVSKPRASK-PGRKRGGRTRKGPKRPQQPNPPSAPLVPG 127
+ + L+R E K + +A K P + + +K PK P+ P P P P
Sbjct: 624 --VDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPK 681
Query: 128 LLDQSNPLSTPMPKKRGRKS------KAELLLLKLSK---------DLDRPESQSPKRPP 172
++ +TP PK + S +A L K++K DLD+ SP PP
Sbjct: 682 --EKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSP--PP 737
Query: 173 EDFETPSGERPRRRAAQV 190
E+ E P G + RR + QV
Sbjct: 738 EEDEDP-GVQKRRSSRQV 754
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 47.0 bits (110), Expect = 8e-05
Identities = 65/279 (23%), Positives = 109/279 (39%), Gaps = 33/279 (11%)
Query: 36 VKTSSEMTSAEASVEMSLPTPL---PGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVS 92
+ + S S E+ + LP P S + LPPE +S +P ++ + V+
Sbjct: 1076 IMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVN 1135
Query: 93 KP--RASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSN---------PLSTPMP- 140
KP A K + + R NP S + G LD S +S+P+P
Sbjct: 1136 KPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPG 1195
Query: 141 KKRGRKSKAELLLLKLSKDLDRPES----QSPKRPPEDF------ETPSG-ERPRRRAAQ 189
KK ++ ++L+ +L K R ++ Q K +D + P G +R R+R
Sbjct: 1196 KKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHT 1255
Query: 190 VALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFF 249
+ Q+ EE L + E + S P K K+ R P G G P++E
Sbjct: 1256 ASESDEQQWPEE--KRLKEDILENEDEQNSPPKKGKRGRPPKPLGG-----GTPKEEPTM 1308
Query: 250 LQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQK 288
+ ++S P+ E E +T + S S + +
Sbjct: 1309 KTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHR 1347
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/262 (20%), Positives = 102/262 (38%), Gaps = 29/262 (11%)
Query: 45 AEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRG 104
AEA + P SP++ + P ++E+ S + S E + P +K K
Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS--PEKAKSPEKEEAKSPEKAKSPVKAE 673
Query: 105 GRTRKGPKRP--QQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKS--------KAELLLL 154
++ + K P + P P + +P P K KS K E
Sbjct: 674 AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733
Query: 155 KLSKDLDRPESQSPKRP--PE-----DFETPSGERPRRRAAQVALLYLQELAEELSTALP 207
+ +K + E++SP++ PE D ++P + P + A+ + E+ + +
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA---DKFPEKAKSPVK 790
Query: 208 APVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESS 267
V PE K SP K P EEV ++E+ + ++V+ E P ++
Sbjct: 791 EEVKSPE--KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE-----KPQEVKVKEPPKKAE 843
Query: 268 SEPEPVVPRSTPRGSTSGKQKP 289
E P P++ + + ++ P
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAP 865
Score = 39.7 bits (91), Expect = 0.013
Identities = 48/213 (22%), Positives = 83/213 (38%), Gaps = 35/213 (16%)
Query: 64 PDQRRLPPEQESLSRLEQPDLS-SEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSA 122
P + PE+E+ S +++ S +E K A P + K P + + +PP A
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 123 PL-----VPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFET 177
+ +P P K KS AE + +K + E++S P + ++
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS----PAEAKS 620
Query: 178 PSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPK-KIRQPAACPGG 236
P E + PA V PE K SPTK + K + A P
Sbjct: 621 PVKEEAKS---------------------PAEVKSPE--KAKSPTKEEAKSPEKAKSPEK 657
Query: 237 EEVDGAPRDEDFFLQVEAEDVEESEGPSESSSE 269
EE +P ++ EA+ E+++ P ++ ++
Sbjct: 658 EEAK-SPEKAKSPVKAEAKSPEKAKSPVKAEAK 689
Score = 37.0 bits (84), Expect = 0.084
Identities = 51/235 (21%), Positives = 89/235 (37%), Gaps = 19/235 (8%)
Query: 74 ESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSN 133
E ++ E+ + E K + + + G K P + +P P + +
Sbjct: 468 EEVTEEEEKEAKEEEGK-EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 134 PLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALL 193
P P+K KS AE +K + P + K PPE ++P E + A +
Sbjct: 527 PAEAKSPEKEEAKSPAE---VKSPEKAKSPAKEEAKSPPE-AKSPEKEEAKSPAEVKSPE 582
Query: 194 YLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE 253
+ A+E + + PA PE K SP K ++ + PA +P E+ E
Sbjct: 583 KAKSPAKEEAKS-PAEAKSPE--KAKSPVK-EEAKSPAEAK-------SPVKEEAKSPAE 631
Query: 254 AEDVEESEGPS-ESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPV 307
+ E+++ P+ E + PE + K K + A + P +PV
Sbjct: 632 VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS--PEKAKSPV 684
Score = 37.0 bits (84), Expect = 0.084
Identities = 52/263 (19%), Positives = 98/263 (37%), Gaps = 35/263 (13%)
Query: 46 EASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGG 105
EA +P+ SP++ + P + ++L ++ P+ + + ++ A K K
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD-VKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 106 RTRKGPKRPQQPNPP-----SAPL--VPGLLDQSNPLS---------TPMPKKRGRKSKA 149
++ K P++ P AP +P + +P+ P K+ + KA
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 150 ELLLL----KLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTA 205
K SK + P+ ++PK E+ + P+ E+P+ + +E AE+
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK----KEEAEDKKKV 903
Query: 206 LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSE 265
P +V KPK+ + A +E D A E ++ E+ E E
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAK----KEPDDAKAKE------PSKPAEKKEAAPE 953
Query: 266 SSSEPEPVVPRSTPRGSTSGKQK 288
E + + T K K
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAK 976
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 46.2 bits (108), Expect = 1e-04
Identities = 66/288 (22%), Positives = 100/288 (34%), Gaps = 50/288 (17%)
Query: 43 TSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPD--LSSEMSKVSKPRASKPG 100
T+ +S P P+ +S + P + + PD LSS+ V + +P
Sbjct: 1980 TAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGATKGKEPA 2039
Query: 101 RKR-GGRTRKGPKRPQQPNPPSAPLVPGLLDQSN------------PLST--------PM 139
+ GG +R+G K + P P PG ++++ PL T P
Sbjct: 2040 TQSLGGSSREG-KGHSKSGPDVFPATPGSQNKASDGIGQGEGGPSVPLHTDRAPLDAKPQ 2098
Query: 140 PKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELA 199
P GR L +L+ L RP P P + + GE+ L
Sbjct: 2099 PTSGGRP----LEVLEKPVHLPRPGHPGPSEPADQKLSAVGEKQT----------LSPKH 2144
Query: 200 EELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVE- 258
+ ST P C + + P QPAA +G E + E + +E
Sbjct: 2145 PKPSTVKDCPTLCKQTDNRQTDKSPS---QPAANTD-RRAEGKKCTEALYAPAEGDKLEA 2200
Query: 259 -----ESEGPSESSSEPEPVVPRSTP--RGSTSGKQKPHCRGMAPNGL 299
SE + + P V + P RG G QKP PNG+
Sbjct: 2201 GLSFVHSENRLKGAERPAAGVGKGFPEARGKGPGPQKPPTEADKPNGM 2248
Score = 36.2 bits (82), Expect = 0.14
Identities = 48/182 (26%), Positives = 71/182 (39%), Gaps = 30/182 (16%)
Query: 14 AGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFE----DSPDQRRL 69
+GP + T + SP S++ S V S+P LP D+ R L
Sbjct: 1622 SGPQASKTELPSP-----------ESAQSPSPSGDVRASVPPVLPSSSGKKNDTTSAREL 1670
Query: 70 PPEQESLSR---LEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVP 126
P +++ LE L + P S P + R RKGP P S P
Sbjct: 1671 SPSSLKMNKSYLLEPWFLPPSRGLQNSPAVSLPDPEFK-RDRKGP----HPTARS----P 1721
Query: 127 GLLDQSNPLSTP--MPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPR 184
G + +SNP PK + + +LL L ++L P+ P+ P +PS E+P
Sbjct: 1722 GTVMESNPQQREGSSPKHQDHTTDPKLLTC-LGQNLHSPDLARPRCPLPPEASPSREKPG 1780
Query: 185 RR 186
R
Sbjct: 1781 LR 1782
Score = 31.2 bits (69), Expect = 4.6
Identities = 49/216 (22%), Positives = 77/216 (35%), Gaps = 29/216 (13%)
Query: 82 PDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPK 141
PD ++ + K A PG K + G RP P S+ G+ P + K
Sbjct: 1834 PDFYTQTQAMEKAWA--PGGKTNHKDGPGEARPP-PRDNSSLHSAGI-----PCEKELGK 1885
Query: 142 -KRGRKSKAELLLLKLSKDLDRPESQSPKRPPE--DFETPSGERPRRRAAQVALLYLQEL 198
+RG + K E LL + S ES+ ++ + + P R+ Q L
Sbjct: 1886 VRRGVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKE--------QPL 1937
Query: 199 AEELSTALPAPV-----SCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE 253
S+ P P+ S P + S R+P A P E +P+D +
Sbjct: 1938 QRHPSSIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAKPSTAEPSSSPQDPPKPVAAH 1997
Query: 254 AEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKP 289
+E P P+P P++ + QKP
Sbjct: 1998 SESSSHKPRPG-----PDPGPPKTKHPDRSLSSQKP 2028
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.4 bits (106), Expect = 2e-04
Identities = 60/234 (25%), Positives = 93/234 (39%), Gaps = 50/234 (21%)
Query: 64 PDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAP 123
P++ R+PP +++ +V P+ P +K K P+ P PP P
Sbjct: 10485 PEEPRVPP--------------TKVPEVLPPKEVVPEKKVPVPPAKKPEAP----PPKVP 10526
Query: 124 LVPGLLDQSNPLSTPMPKKRG-------RKSKAELLLLKLSKDLDRPESQSPKRPPEDFE 176
P + + P PKK KA + K+ + + P+ +SP PPE E
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP-PKPESP--PPEVPE 10583
Query: 177 TPSGERPRRRAA-------QVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKI-- 227
P P ++ +V + + E +E+ PV P+ P+V PTK ++
Sbjct: 10584 APKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP-PTKVPEVPK 10642
Query: 228 ------RQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVP 275
+ P A P E +P E F E E+V E P+E EPEP P
Sbjct: 10643 VAVPEKKVPEAIPPKPE---SPPPEVF---EEPEEVALEEPPAEVVEEPEPAAP 10690
Score = 41.2 bits (95), Expect = 0.004
Identities = 65/287 (22%), Positives = 109/287 (37%), Gaps = 44/287 (15%)
Query: 23 VDSPGQEVLNQLDV-KTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQ 81
V P +EV + V + E+ E + E + T + + ++ + E+E ++ E
Sbjct: 9883 VPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV 9942
Query: 82 ----PDLSSEMSKVSKPRASKP---GRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNP 134
P E+ + P KP +K+ K P+ P++P L+P ++ P
Sbjct: 9943 VPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK-EKPPP 10001
Query: 135 LSTP-MPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP-----SGERPRRRAA 188
P +PKK + K + + K + + PK+P + + P E P +
Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 189 QVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEV--------- 239
+V + E E+ T +P V P PKV P K + + P A P EEV
Sbjct: 10062 EVPKKLIPE--EKKPTPVPKKVEAPP-PKV--PKKREPVPVPVALPQEEEVLFEEEIVPE 10116
Query: 240 ---------------DGAPRDEDFFLQVEAEDVEESEGPSESSSEPE 271
+ P +E+ + E EE E P E PE
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE 10163
Score = 37.0 bits (84), Expect = 0.084
Identities = 46/222 (20%), Positives = 83/222 (37%), Gaps = 23/222 (10%)
Query: 28 QEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFED--------SPDQRRLPPEQESLSRL 79
+EVL + ++ E+ E V LP E+ P++ +PPE+E +
Sbjct: 10105 EEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEE 10164
Query: 80 EQPDLSSEMSKVSKPRASKPG------RKRGGRTRKGPKRPQQPNPPSAPLVPGLLD--- 130
E+ E+ KP+ P +K + PK+ + P P P VP ++
Sbjct: 10165 EEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP-PAKVPEVPKKVEEKR 10223
Query: 131 -----QSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRR 185
+ L + ++ + +E + + ++ E +P R PE + E P
Sbjct: 10224 IILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTP 10283
Query: 186 RAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKI 227
+V + + +P PV E P P PKK+
Sbjct: 10284 VPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKV 10325
Score = 37.0 bits (84), Expect = 0.084
Identities = 52/244 (21%), Positives = 88/244 (36%), Gaps = 34/244 (13%)
Query: 58 PGFEDSPDQRR-LPPEQESLSRLEQPDLSSEMSKV---------SKPRASKPGRKRGGRT 107
P E +P++ + +P +E + P + E K+ KP A P +
Sbjct: 10812 PEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871
Query: 108 RKGPKRPQQPNPPSAPLVPGLLDQSNPL-------STPMPKKRGRKSKAELLLLKLSKDL 160
+ PK +P PP P P D + +P+K K EL LK+
Sbjct: 10872 IEKPKLKPRPPPP--PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGE 10929
Query: 161 DRPESQSPKRPPEDFE-----TPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEG 215
+ P+R PE E + +RP +V L+++ + P P E
Sbjct: 10930 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 10989
Query: 216 PKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVP 275
+ + +KI +P P E+ A + + A + + + +P PV P
Sbjct: 10990 EVPTVTKRERKIPEPTKVP---EIKPA-------IPLPAPEPKPKPEAEVKTIKPPPVEP 11039
Query: 276 RSTP 279
TP
Sbjct: 11040 EPTP 11043
Score = 32.0 bits (71), Expect = 2.7
Identities = 51/220 (23%), Positives = 83/220 (37%), Gaps = 33/220 (15%)
Query: 50 EMSLPTPLPGFEDSPDQRRLP-PEQESLSR-----LEQPDLSSEMSKVSKPRASKPGRKR 103
E +P +P +SP PE+ +L +E+P+ ++ P+ P +K
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKA 10706
Query: 104 GGRTRKGPKRP--QQPNPPS-------APLVPGLLDQSNPLSTP------MPKKR-GRKS 147
K P+ P + P P PLV ++ P P +P+K+
Sbjct: 10707 PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766
Query: 148 KAELLLLKLSKDLDRPESQS------PKR----PPEDFETPSGERPRRRAAQVALLYLQE 197
K E+ K+ + +P + P+R PPE +E P P A +
Sbjct: 10767 KPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP- 10825
Query: 198 LAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGE 237
+AEE +P P E K+ K I++P A P E
Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKE 10865
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/189 (29%), Positives = 64/189 (33%), Gaps = 27/189 (14%)
Query: 61 EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPK-------- 112
E SP RR P L R LSS + +S P S P + R P
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 269
Query: 113 --RPQQPNPPSAPLVPGLLD-QSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPK 169
RP Q PP P L S+PL+TP P S L + L P P
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL-----QTLPSP----PA 320
Query: 170 RPPEDFETPSGERPRRRAAQVALLY--LQELAEELSTALPA----PVSCPEGPKVSSPTK 223
PP T G P +A L L LA A PA P+ P P S P
Sbjct: 321 TPPSQATTSLGS-PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379
Query: 224 PKKIRQPAA 232
P P A
Sbjct: 380 PLATPSPQA 388
Score = 32.0 bits (71), Expect = 2.7
Identities = 66/279 (23%), Positives = 90/279 (32%), Gaps = 62/279 (22%)
Query: 39 SSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
+S S A+ P PL P Q PP Q + P + + P AS
Sbjct: 448 ASPPMSPSATPPPQAPPPLAA---PPLQLAKPPPQAPPALATPP-----LQALPSPPASF 499
Query: 99 PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
PG+ + P P PP AP V P S P
Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA------------------- 540
Query: 159 DLDRPESQSPKRPPEDFETPSGERPRRRAAQV------------ALLYLQELAEELSTAL 206
P Q+P+RPP S PR A + L +LA S+A
Sbjct: 541 ---SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 207 PAPV------SCPEGPKVSSPTKPKKI---------RQPAACPGGEEVDGAPRDEDFFLQ 251
P S PEG +SP ++ R PA GAP
Sbjct: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657
Query: 252 VEAED----VEESEGPSESSSEPEPVVPRSTPRGSTSGK 286
+ D + E+EGP ++ P + P +P G++ GK
Sbjct: 658 PGSADGLCTIYETEGPESATPAPGALDPGPSP-GTSGGK 695
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 38/293 (12%)
Query: 34 LDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLP--------PEQESLSRLEQPDLS 85
LD+K S +S +S E+S S P P +E S P++
Sbjct: 1369 LDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMK 1428
Query: 86 SEMSKVSKPRA---SKPGRKRGGRTRK----GPKRPQQPNPPSAPLVPGLLDQSNPL--- 135
+ + R+ S PG + G T P + P P S+P
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKA 1488
Query: 136 --STPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALL 193
TP P+ R S EL L+ +R S+S TP G+R R ++Q +
Sbjct: 1489 LPQTPRPRSRS-PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 194 YLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDG----APRDEDFF 249
+E S + +P S K +P +RQ + EVD +PR
Sbjct: 1548 KPSASPQERSESDSSPDS---KAKTRTP-----LRQRSRSGSSPEVDSKSRLSPRRSRSG 1599
Query: 250 LQVEAED----VEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNG 298
E +D ++ S+SS EP+ PR+ PR S SG RG +P G
Sbjct: 1600 SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG-RGPSPEG 1651
Score = 37.4 bits (85), Expect = 0.064
Identities = 57/259 (22%), Positives = 93/259 (35%), Gaps = 24/259 (9%)
Query: 45 AEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRG 104
++A +SL L G P Q+ P + S S QP S +S P K+
Sbjct: 767 SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQK 826
Query: 105 GRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPM-------PKKRGRKSKAELLLLKLS 157
+T ++ + P + G + +++P P++R + LK S
Sbjct: 827 SKTPS--RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK-S 883
Query: 158 KDLDRPESQSPKRPPEDFETPSGERPRRRAA---QVALLYLQELAEELSTALPAPVSCPE 214
+ R P TP + P R ++ +V + ++ P+P
Sbjct: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP----- 938
Query: 215 GPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSS---EPE 271
+V+S T P++ R + C E PR V+ P +S S P
Sbjct: 939 -SRVTSRTTPRRSRSVSPC-SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
Query: 272 PVVPRSTPRG-STSGKQKP 289
P V TP G S SG + P
Sbjct: 997 PKVKAQTPPGPSLSGSKSP 1015
Score = 36.6 bits (83), Expect = 0.11
Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 14/162 (8%)
Query: 38 TSSEMTSAEASVEMSL---PTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKP 94
+ SE +S E++L P+P P +++ + R PPE R + SS S S
Sbjct: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR-PPEPTPAKRKRRSSSSSSSSSSSSS 2619
Query: 95 RASKPGRKRGGRTRKGPKRPQQPNPPSA---PLVPG---LLDQSNPLSTPMPKKRGRKSK 148
+S + + S+ P PG L ++P P ++R R +
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR 2679
Query: 149 AELLLLKLSKDLDRPESQ----SPKRPPEDFETPSGERPRRR 186
+ L+ S+ L + SP+ P D ++ S ER RR
Sbjct: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
Score = 33.5 bits (75), Expect = 0.93
Identities = 48/242 (19%), Positives = 86/242 (35%), Gaps = 35/242 (14%)
Query: 54 PTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKR 113
P P +S R P+Q+ + + SE S + R K +K+ R+ K+
Sbjct: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRER-KKSSKKKKHRSESESKK 226
Query: 114 PQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPE 173
+ +P TP K++ + K + + P+S+ R
Sbjct: 227 RKHRSP-----------------TPKSKRKSKDKKRK----RSRSTTPAPKSRRAHRSTS 265
Query: 174 DFETPSGERPRRRAAQVALLYLQELAEELSTAL----PAPVSCPEGPKVSSPTKP--KKI 227
S + R R+ A A+ +TAL P+P S G + ++P
Sbjct: 266 ADSASSSDTSRSRSRSAA-------AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST 318
Query: 228 RQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQ 287
++P++ + +P ++ + E S P SS+ PEP P G
Sbjct: 319 QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378
Query: 288 KP 289
+P
Sbjct: 379 QP 380
Score = 30.8 bits (68), Expect = 6.0
Identities = 57/269 (21%), Positives = 86/269 (31%), Gaps = 30/269 (11%)
Query: 38 TSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKV----SK 93
+ S MTS A P+P +P Q LPP Q+ R P S+ S+ +
Sbjct: 2415 SQSRMTSERA------PSPSSRMGQAPSQSLLPPAQDQ-PRSPVPSAFSDQSRCLIAQTT 2467
Query: 94 PRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGL--LDQSNPLSTPMPKKRGRKSKAEL 151
P A G S P PG+ D P P G + + L
Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVP-APGVPHSDVGEP-----PASTGAQQPSAL 2521
Query: 152 LLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTAL---PA 208
L+ +K+ S S + S + + L + AL P+
Sbjct: 2522 AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS 2581
Query: 209 PVSCP-----EG-PKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEG 262
P P EG P +P K K+ ++ + + S
Sbjct: 2582 PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
Query: 263 PSESSSEPEPVV--PRSTPRGSTSGKQKP 289
S SSS P P P++ P+ ++ K P
Sbjct: 2642 SSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/261 (21%), Positives = 96/261 (36%), Gaps = 37/261 (14%)
Query: 38 TSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRAS 97
+++ +TS+ A PTP+ +P + L+ P L+S ++ S P +
Sbjct: 1824 SAAAITSSSAPASAPAPTPILASVSTPASVTI------LASASIPILASALASTSAPTPA 1877
Query: 98 KPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLS 157
P P S PL P P TP+ +
Sbjct: 1878 PAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTH 1937
Query: 158 KDLDRP---ESQSPKRPPEDFETPSG---------------ERPRRRAAQVALLYLQELA 199
K + P SQS K+PP PS + P+ A L+ ++A
Sbjct: 1938 KPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVA 1997
Query: 200 -----EELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEA 254
++S L P+S P+ P VS+ KP + + P E GA ++ L++
Sbjct: 1998 PPAVLNDISKKL-GPISPPQPPSVSAWNKP--LTSFGSAPSSE---GAKNGQESGLEIGT 2051
Query: 255 EDVEESEGPSESSSEPEPVVP 275
+ ++ P+ + +E E VVP
Sbjct: 2052 DTIQFG-APASNGNENE-VVP 2070
Score = 39.3 bits (90), Expect = 0.017
Identities = 61/264 (23%), Positives = 107/264 (40%), Gaps = 27/264 (10%)
Query: 32 NQLDVKTSSEMT--SAEASVEMSLPTPL----PGFEDSPDQRRL--PPEQESLSRLEQPD 83
NQL+ ++ S+EA V+ L + P D+ +Q P+Q++LS ++
Sbjct: 852 NQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEER 911
Query: 84 LSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTP--MPK 141
+S+ S+ S+ R+ G T+K ++ +P+ + +D P+ P PK
Sbjct: 912 ISAVESQPSRKRSVSHG---SNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPK 968
Query: 142 KRGR-KSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAE 200
K G +S K+ K + E++ RP + +RP RR+ + L+++ E
Sbjct: 969 KEGFIRSSEGPKPEKVYKS--KSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKE 1026
Query: 201 ELSTALPAPVSCPEGPKVSSPTKPKKIRQ----PAACPGGEEVDGAPRDEDFFLQVEAED 256
E E KP+K + P P P+ +Q EAE
Sbjct: 1027 EREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEK 1086
Query: 257 VEESE------GPSESSSEP-EPV 273
+E PS+ + +P EPV
Sbjct: 1087 FPSTETATLAQKPSQDTEKPLEPV 1110
Score = 38.1 bits (87), Expect = 0.038
Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 16/111 (14%)
Query: 94 PRASKPGRKRGGRTRKGPKRPQ-QPNPPSAPLVPGLLD-QSNPLSTPMPKKR-GRKSKAE 150
P+ R RGG R+G + P +P+ PS P D Q NP + +PK G +
Sbjct: 1335 PKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRH 1394
Query: 151 LLLLKLSKDL-------------DRPESQSPKRPPEDFETPSGERPRRRAA 188
+ ++ D +RP Q P RPP + P R R R A
Sbjct: 1395 EQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREA 1445
Score = 31.2 bits (69), Expect = 4.6
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 24/106 (22%)
Query: 95 RASKPGRKRGGR--TRKGPK----RPQQPNPPSAPLVPGLLDQSNPLSTP---MPKKRGR 145
R S GR RGGR TR P+ +P+ + PS PL ++ S+ +PK+R +
Sbjct: 1201 RGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQ 1260
Query: 146 K---------------SKAELLLLKLSKDLDRPESQSPKRPPEDFE 176
+ K L KL K +RPE++ P +P F+
Sbjct: 1261 RGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFK 1306
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.1 bits (105), Expect = 3e-04
Identities = 66/278 (23%), Positives = 104/278 (37%), Gaps = 31/278 (11%)
Query: 21 TVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSP-DQRRLPPEQESLSRL 79
T D P +V +Q + KT+ + + A S P G + SP D + +P +
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT--GEKVSPFDSKAIPRPASDSKII 831
Query: 80 EQPDLSSEMS--KVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQS----- 132
P SSE K P K K+ +T+ PK +P P +P PG +
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKA-QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
Query: 133 NPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVAL 192
P +P P+++ R+ L L D P+SQ P ET +G +
Sbjct: 891 TPQQSPKPQEQSRR-----FSLNLGSITDAPKSQ----PTTPQETVTG-----KLFGFGA 936
Query: 193 LYLQELAEELSTA-LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQ 251
+ + +STA P P S GP P + P + + AP +
Sbjct: 937 SIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIP 995
Query: 252 VEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKP 289
V+ +E++ P+ EP+ + R T K P
Sbjct: 996 VK----KETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 37.7 bits (86), Expect = 0.049
Identities = 59/262 (22%), Positives = 89/262 (33%), Gaps = 37/262 (14%)
Query: 54 PTPLPGFEDSPDQR---RLPPEQESLSRLEQ-----PDLSSEMSKVSKPRASKPGRKRGG 105
P PG P Q PP Q++ S P ++ V K A +PG +
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 106 RTRKGPKRP--QQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRP 163
+ G +P QQP S PG P+ P P K + +P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 164 ESQ--SPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSP 221
SQ P +PP P+ P++ + + +++ + P P GP SP
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSA------KPPSQQPGSTKPPPQQ--PGPAKPSP 521
Query: 222 TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRG 281
+P + P+ PG + ++S P + +P+ P P
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSP------AKPSAQQSTKPVSQTGSGKPLQP---PTV 572
Query: 282 STSGKQKPHCRGMAPNGLPNHI 303
S S KQ P GLP I
Sbjct: 573 SPSAKQPP------SQGLPKTI 588
Score = 35.0 bits (79), Expect = 0.32
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 18/135 (13%)
Query: 43 TSAEASVEMSLPTPLPGFEDSPDQR----RLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
TSA+ + P+ LPG P Q+ + PP+Q S +P ++K
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----------GSAKPPSQQPGSTK 508
Query: 99 PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
P ++ G + P++P PPS PG S +P K ++S + K
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQPSP-AKPSAQQSTKPVSQTGSGK 565
Query: 159 DLDRPE-SQSPKRPP 172
L P S S K+PP
Sbjct: 566 PLQPPTVSPSAKQPP 580
Score = 34.7 bits (78), Expect = 0.42
Identities = 63/290 (21%), Positives = 102/290 (35%), Gaps = 64/290 (22%)
Query: 48 SVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRT 107
SV+ SLP+P P + P +Q + S+P +KP + G T
Sbjct: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK-------------SQPGPAKPPAQPSGLT 339
Query: 108 RKGPKRPQQPN----------PPSAPLVPG------------LLDQSNPLSTPMPKKRGR 145
+ ++P PP+ PL P +Q P + P G+
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 146 -------KSKAELLLLKLSKDL-DRPESQSPKRPPEDFETP-----SGERPRRRAAQVAL 192
+K + K L +P QSP + P +TP G+ P ++A
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 193 LYLQELAEELSTALPAPVSCP---EGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFF 249
Q + + LP P P GP P +P + P+ PG + P +
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK---PPPQQPGP 516
Query: 250 LQVEAEDVEESEGPSE-------SSSEPEPVVP---RSTPRGSTSGKQKP 289
+ + ++ PS+ S+ +P P P +ST S +G KP
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566
Score = 31.2 bits (69), Expect = 4.6
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 57 LPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQ 116
LP EDS ++ L E+E L E+ E+ + + +SK +K R +R +
Sbjct: 1767 LPTIEDSSEEEELREEEELLKEQEK---QREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823
Query: 117 PNPPS 121
PPS
Sbjct: 1824 KTPPS 1828
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.1 bits (105), Expect = 3e-04
Identities = 66/278 (23%), Positives = 104/278 (37%), Gaps = 31/278 (11%)
Query: 21 TVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSP-DQRRLPPEQESLSRL 79
T D P +V +Q + KT+ + + A S P G + SP D + +P +
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT--GEKVSPFDSKAIPRPASDSKII 831
Query: 80 EQPDLSSEMS--KVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQS----- 132
P SSE K P K K+ +T+ PK +P P +P PG +
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKA-QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
Query: 133 NPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVAL 192
P +P P+++ R+ L L D P+SQ P ET +G +
Sbjct: 891 TPQQSPKPQEQSRR-----FSLNLGSITDAPKSQ----PTTPQETVTG-----KLFGFGA 936
Query: 193 LYLQELAEELSTA-LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQ 251
+ + +STA P P S GP P + P + + AP +
Sbjct: 937 SIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIP 995
Query: 252 VEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKP 289
V+ +E++ P+ EP+ + R T K P
Sbjct: 996 VK----KETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 37.7 bits (86), Expect = 0.049
Identities = 59/262 (22%), Positives = 89/262 (33%), Gaps = 37/262 (14%)
Query: 54 PTPLPGFEDSPDQR---RLPPEQESLSRLEQ-----PDLSSEMSKVSKPRASKPGRKRGG 105
P PG P Q PP Q++ S P ++ V K A +PG +
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 106 RTRKGPKRP--QQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRP 163
+ G +P QQP S PG P+ P P K + +P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 164 ESQ--SPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSP 221
SQ P +PP P+ P++ + + +++ + P P GP SP
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSA------KPPSQQPGSTKPPPQQ--PGPAKPSP 521
Query: 222 TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRG 281
+P + P+ PG + ++S P + +P+ P P
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSP------AKPSAQQSTKPVSQTGSGKPLQP---PTV 572
Query: 282 STSGKQKPHCRGMAPNGLPNHI 303
S S KQ P GLP I
Sbjct: 573 SPSAKQPP------SQGLPKTI 588
Score = 35.0 bits (79), Expect = 0.32
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 18/135 (13%)
Query: 43 TSAEASVEMSLPTPLPGFEDSPDQR----RLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
TSA+ + P+ LPG P Q+ + PP+Q S +P ++K
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----------GSAKPPSQQPGSTK 508
Query: 99 PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
P ++ G + P++P PPS PG S +P K ++S + K
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQPSP-AKPSAQQSTKPVSQTGSGK 565
Query: 159 DLDRPE-SQSPKRPP 172
L P S S K+PP
Sbjct: 566 PLQPPTVSPSAKQPP 580
Score = 34.7 bits (78), Expect = 0.42
Identities = 63/290 (21%), Positives = 102/290 (35%), Gaps = 64/290 (22%)
Query: 48 SVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRT 107
SV+ SLP+P P + P +Q + S+P +KP + G T
Sbjct: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK-------------SQPGPAKPPAQPSGLT 339
Query: 108 RKGPKRPQQPN----------PPSAPLVPG------------LLDQSNPLSTPMPKKRGR 145
+ ++P PP+ PL P +Q P + P G+
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 146 -------KSKAELLLLKLSKDL-DRPESQSPKRPPEDFETP-----SGERPRRRAAQVAL 192
+K + K L +P QSP + P +TP G+ P ++A
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 193 LYLQELAEELSTALPAPVSCP---EGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFF 249
Q + + LP P P GP P +P + P+ PG + P +
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK---PPPQQPGP 516
Query: 250 LQVEAEDVEESEGPSE-------SSSEPEPVVP---RSTPRGSTSGKQKP 289
+ + ++ PS+ S+ +P P P +ST S +G KP
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566
Score = 31.2 bits (69), Expect = 4.6
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 57 LPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQ 116
LP EDS ++ L E+E L E+ E+ + + +SK +K R +R +
Sbjct: 1767 LPTIEDSSEEEELREEEELLKEQEK---QREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823
Query: 117 PNPPS 121
PPS
Sbjct: 1824 KTPPS 1828
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 44.7 bits (104), Expect = 4e-04
Identities = 55/233 (23%), Positives = 81/233 (34%), Gaps = 23/233 (9%)
Query: 52 SLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGP 111
+LP PL Q PP +S P S+ S + PG
Sbjct: 790 ALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT--------- 840
Query: 112 KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP 171
P QP P+ P P P TP ++++ + ++ P+ Q+P +P
Sbjct: 841 --PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP 898
Query: 172 PEDFETP--SGERPRRRAAQVALLYLQELAEELSTALPAPVSCPE--------GPKVSSP 221
P TP S ++P AQ L + A + +P P S GP V
Sbjct: 899 P-SVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVL 957
Query: 222 TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE-AEDVEESEGPSESSSEPEPV 273
+ + P E G PR E ++ A V+E +E SEP V
Sbjct: 958 EMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEV 1010
Score = 32.0 bits (71), Expect = 2.7
Identities = 48/197 (24%), Positives = 70/197 (35%), Gaps = 35/197 (17%)
Query: 72 EQESLSRLEQPDLS----SEMSKVSKPRASKPGRKRG--GRTRKGPKRPQQPNPPSAPLV 125
+Q+ RL+Q L + M+ + P+ S P G + P PQ P PP+ P
Sbjct: 1814 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-- 1871
Query: 126 PGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP----SGE 181
Q +P+S G S A + +P SQ P PP P +
Sbjct: 1872 -----QPSPVSM---SPAGFPSVAR-TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAAR 1922
Query: 182 RPRRRAAQVALLYLQELAEEL-----------STALPAPVSCPEGPKVSSPTKPKKIR-- 228
+ R A Q LY + + S P ++ P +VS P P
Sbjct: 1923 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ 1982
Query: 229 -QPAACPGGEEVDGAPR 244
Q A P + + G PR
Sbjct: 1983 WQQAPLPQQQPMPGLPR 1999
Score = 31.6 bits (70), Expect = 3.5
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 718 GTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSG 777
G A + G+ IA L + +P V+ P + P + + Q P P H S +G
Sbjct: 2285 GQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPS-PHHVSPQTG 2343
Query: 778 VPNPPKARTYTETVNHHYL 796
P+P A T +++ +L
Sbjct: 2344 SPHPGLAVTMASSIDQGHL 2362
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 44.7 bits (104), Expect = 4e-04
Identities = 55/233 (23%), Positives = 81/233 (34%), Gaps = 23/233 (9%)
Query: 52 SLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGP 111
+LP PL Q PP +S P S+ S + PG
Sbjct: 828 ALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT--------- 878
Query: 112 KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP 171
P QP P+ P P P TP ++++ + ++ P+ Q+P +P
Sbjct: 879 --PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP 936
Query: 172 PEDFETP--SGERPRRRAAQVALLYLQELAEELSTALPAPVSCPE--------GPKVSSP 221
P TP S ++P AQ L + A + +P P S GP V
Sbjct: 937 P-SVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVL 995
Query: 222 TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE-AEDVEESEGPSESSSEPEPV 273
+ + P E G PR E ++ A V+E +E SEP V
Sbjct: 996 EMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEV 1048
Score = 32.0 bits (71), Expect = 2.7
Identities = 48/197 (24%), Positives = 70/197 (35%), Gaps = 35/197 (17%)
Query: 72 EQESLSRLEQPDLS----SEMSKVSKPRASKPGRKRG--GRTRKGPKRPQQPNPPSAPLV 125
+Q+ RL+Q L + M+ + P+ S P G + P PQ P PP+ P
Sbjct: 1852 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-- 1909
Query: 126 PGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP----SGE 181
Q +P+S G S A + +P SQ P PP P +
Sbjct: 1910 -----QPSPVSM---SPAGFPSVAR-TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAAR 1960
Query: 182 RPRRRAAQVALLYLQELAEEL-----------STALPAPVSCPEGPKVSSPTKPKKIR-- 228
+ R A Q LY + + S P ++ P +VS P P
Sbjct: 1961 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ 2020
Query: 229 -QPAACPGGEEVDGAPR 244
Q A P + + G PR
Sbjct: 2021 WQQAPLPQQQPMPGLPR 2037
Score = 31.6 bits (70), Expect = 3.5
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 718 GTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSG 777
G A + G+ IA L + +P V+ P + P + + Q P P H S +G
Sbjct: 2323 GQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPS-PHHVSPQTG 2381
Query: 778 VPNPPKARTYTETVNHHYL 796
P+P A T +++ +L
Sbjct: 2382 SPHPGLAVTMASSIDQGHL 2400
>gi|4507703 tumor suppressing subtransferable candidate 1 [Homo
sapiens]
Length = 387
Score = 44.7 bits (104), Expect = 4e-04
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 611 AHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYN 668
AH Q VR L + ++L S G D K+KFWD R EP+ +++ + W + YN
Sbjct: 226 AHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEE--HSHWVWNVRYN 281
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 44.3 bits (103), Expect = 5e-04
Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 26/201 (12%)
Query: 40 SEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKP 99
S + S + S P+ LP + P+ + PPE S L P E P S
Sbjct: 623 SSLQSPVSICSSSTPSSLP--QSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPE 680
Query: 100 GRKRGGRTRKGPKRPQQP----------NPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKA 149
G + + PQ P + P +P P D +PL P +G ++
Sbjct: 681 SAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSP--PEWEDSLSPLHFPQFPPQGEDFQS 738
Query: 150 ELL----LLKLSKDLDRPES--QSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELS 203
L + S L P+S +SP+ PPE +RP V+ + LA L
Sbjct: 739 SLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRP------VSSFFSYTLASLLQ 792
Query: 204 TALPAPVSCPEGPKVSSPTKP 224
++ +P S PEGP S P
Sbjct: 793 SSHESPQSPPEGPAQSPLQSP 813
Score = 31.2 bits (69), Expect = 4.6
Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 5/123 (4%)
Query: 53 LPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPK 112
+P+ L +SP P ++S S L+ P S E P S R G + +
Sbjct: 11 MPSLLQSSSESPQS--CPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEGEDSSDPLQ 68
Query: 113 RPQQPNPPSAPL-VPGLLDQSNPLSTPMPKKRGR-KSKAELLLLKLSKDLDRPES-QSPK 169
RP + +PL +P + + +P+ + + K L L++S+ E QSP
Sbjct: 69 RPPEGKDSQSPLQIPQSSPEGDDTQSPLQNSQSSPEGKDSLSPLEISQSPPEGEDVQSPL 128
Query: 170 RPP 172
+ P
Sbjct: 129 QNP 131
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 43.9 bits (102), Expect = 7e-04
Identities = 80/339 (23%), Positives = 120/339 (35%), Gaps = 54/339 (15%)
Query: 9 VALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRR 68
V L A P G + SP Q + + L V++ + S S M++P+P G+ SP
Sbjct: 962 VPLPSANPPGPLK---SP-QVLGSSLSVRSPTGSPSRLKSPSMAVPSP--GWVASPKTAM 1015
Query: 69 LPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQP---NPPSAPLV 125
P +S+ +QP L+ S + ++G GP+ NPPS +
Sbjct: 1016 PSP---GVSQNKQPPLNMNSS------TTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMN 1066
Query: 126 PGLLDQSNPLSTP----------------MPKKRGRKSKAELLLLKLSKDLDRPESQSPK 169
P L S+P TP MP A + +L P
Sbjct: 1067 PSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPP 1126
Query: 170 RPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCP---EGPKVSSPTKPKK 226
PP P G P +Q + ++L A + + P P E P P+
Sbjct: 1127 PPP-----PQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPL 1181
Query: 227 IRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPR-STPRGSTS- 284
P + G P++ + + GP SSS+ P PR P G+ +
Sbjct: 1182 GSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAP 1241
Query: 285 --------GKQKPHCRGMA--PNGLPNHIMAPVWKCLHL 313
G Q+ + GMA P LPN P+ HL
Sbjct: 1242 TGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHL 1280
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 43.1 bits (100), Expect = 0.001
Identities = 73/340 (21%), Positives = 109/340 (32%), Gaps = 65/340 (19%)
Query: 16 PVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPE--- 72
PVG +++ + +QLD + A V+ + ED D E
Sbjct: 300 PVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHR 359
Query: 73 -QESLSRLEQPDLSSEMSKVSKPRASKPGRK-------RGGRTRKGPKRPQQP------- 117
+S S E+P ++ K + P + P K R T GP P+ P
Sbjct: 360 DSQSASGEERPP-EADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRG 418
Query: 118 ---------------NPPSAPLVPGLLDQ---------SNPLSTPMPKKRGRKSKAELLL 153
PP P P D+ S+ +S + + R R+ + E
Sbjct: 419 PAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEE--- 475
Query: 154 LKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCP 213
++ ++ ++ KR E F P AA A + LPAP P
Sbjct: 476 RRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAP---P 532
Query: 214 EGPKVSSPTKPKKIRQPAACPGGEEV-------------DGAPRDEDFFLQVEAEDVEES 260
P S+PT + +PA P + G EA VE
Sbjct: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ 592
Query: 261 EGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
E PE V P +TP K +P G+ P P
Sbjct: 593 LPSKEGPEPPEEVPPPTTP---PVPKVEPKGDGIGPTRQP 629
Score = 32.0 bits (71), Expect = 2.7
Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 9/131 (6%)
Query: 13 EAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPT---PLPGFEDSPDQRRL 69
EA PV + G E ++ T+ + E + PT P G Q+ L
Sbjct: 585 EASPV-EPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSL 643
Query: 70 PP-----EQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPL 124
PP +QE L + +Q + + S P P T PQ P PP L
Sbjct: 644 PPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKAL 703
Query: 125 VPGLLDQSNPL 135
PG L + P+
Sbjct: 704 YPGALGRPPPM 714
Score = 30.8 bits (68), Expect = 6.0
Identities = 57/254 (22%), Positives = 82/254 (32%), Gaps = 45/254 (17%)
Query: 50 EMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRK 109
++ L P PG SP R ++ +V PR R RGG
Sbjct: 1134 QVPLAPPPPGAPPSPAPARF---------------TARGGRVFTPRGVPSRRGRGGG--- 1175
Query: 110 GPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPK 169
+ P Q P +P L + P P K K K L+ LS P ++
Sbjct: 1176 --RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEK--LIPGPLS-----PVARGGS 1226
Query: 170 RPPEDFETPSGERPRRR-----AAQVALLYLQELAEELSTA-----------LPAPVSCP 213
+ GERPRRR Q + L +E A LPA P
Sbjct: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP 1286
Query: 214 EGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPV 273
E + P R A P + +E++ E+ D + + P +
Sbjct: 1287 EEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLL 1346
Query: 274 VPRS--TPRGSTSG 285
P++ TP G G
Sbjct: 1347 TPKAVGTPGGGGGG 1360
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/255 (20%), Positives = 99/255 (38%), Gaps = 26/255 (10%)
Query: 66 QRRLPPEQESLSR--LEQPDLS-SEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSA 122
+++ PP ++ S+ L PD + + + +P PG + GPK P+ N P
Sbjct: 915 KKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL--PGEQGINLDNSGPKLPEFSNRP-- 970
Query: 123 PLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGER 182
P P + PL P+ + + + +P+ ++PP + S ++
Sbjct: 971 PGYPSQPVEQRPLQQMPPQLMQHVAPPP----QPPQQQPQPQLPQQQQPPPPSQPQSQQQ 1026
Query: 183 PRRRAAQVALLYLQELAEELSTALPAPVSCPEGP-KVSSPTKPKK----------IRQPA 231
+++ + +L +Q+ + + + V P GP S P + ++ PA
Sbjct: 1027 QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPA 1086
Query: 232 ACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHC 291
+ P + P + L + + E P SS P + SG + P
Sbjct: 1087 SVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSP---LAEMASLPEASGSEAPSV 1143
Query: 292 RGMAPNGLPNHIMAP 306
G PN +P+H++ P
Sbjct: 1144 PG-GPNNMPSHVVLP 1157
Score = 33.1 bits (74), Expect = 1.2
Identities = 37/161 (22%), Positives = 59/161 (36%), Gaps = 26/161 (16%)
Query: 64 PDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAP 123
P Q++ PP + S+ +Q M + + K R Q +PP P
Sbjct: 1010 PQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVS---------QNVHPPRGP 1060
Query: 124 LVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERP 183
L NP S MP ++ S + +++ L P S +R P TP G
Sbjct: 1061 L--------NPDSQRMPMQQ---SGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109
Query: 184 RRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKP 224
R+ ++Y + S+ L S PE +P+ P
Sbjct: 1110 RK------MVYQESPQNPSSSPLAEMASLPEASGSEAPSVP 1144
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/187 (26%), Positives = 69/187 (36%), Gaps = 29/187 (15%)
Query: 13 EAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPE 72
EA VDS G E ++D++T E + E M PLP + P R PPE
Sbjct: 1172 EAALAPGAPAVDSLGME--EEVDIET--EAVAPEERPSMLDEPPLPVGVEEPADSREPPE 1227
Query: 73 QESLSR----LEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKR------------PQQ 116
+ LS+ L P+ ++ + P + + + P P+
Sbjct: 1228 EPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRP 1287
Query: 117 PNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFE 176
P PPS P P D S+P P P L L+K SQS + P
Sbjct: 1288 PRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAK------SQSTETVP---A 1338
Query: 177 TPSGERP 183
TP GE P
Sbjct: 1339 TPGGEPP 1345
Score = 32.0 bits (71), Expect = 2.7
Identities = 47/181 (25%), Positives = 63/181 (34%), Gaps = 41/181 (22%)
Query: 53 LPTPL----PGFEDSPDQ-RRLPPEQESLSR-LEQPDLSSEMSK---------------- 90
LP PL P + P + RR PP SL L +P + + +
Sbjct: 1461 LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520
Query: 91 VSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAP-------LVPGLLDQSNPLSTPMPKKR 143
PR + G P P QP PP P L LD P P R
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580
Query: 144 GRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGE----------RPRRRAAQVALL 193
GR E ++L+K P + PK+ ED P+G RPR ++ +L
Sbjct: 1581 GRDEVTE-EYMELAKSRG-PWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTIL 1638
Query: 194 Y 194
Y
Sbjct: 1639 Y 1639
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 42.7 bits (99), Expect = 0.002
Identities = 66/291 (22%), Positives = 100/291 (34%), Gaps = 60/291 (20%)
Query: 36 VKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQE--SLSRLEQPDLSSEMSKVSK 93
+++ + S +A + S P P D + PP+ E L + QP+LS K
Sbjct: 9 MESHQDFRSIKAKFQASQPEP-------SDLPKKPPKPEFGKLKKFSQPELSEHPKKAPL 61
Query: 94 PR----ASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSN----PLSTPMPKKRGR 145
P + KP K P P+ + P P P + D P T +PKK
Sbjct: 62 PEFGAVSLKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKK--- 118
Query: 146 KSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTA 205
++L L LSK P+ + P + + GE P L +
Sbjct: 119 --PSKLELSDLSKKF--PQLGATPFPRKPLQPEVGEAP------------------LKAS 156
Query: 206 LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSE 265
LP P G P +P ++ PA P + PR Q EA + E
Sbjct: 157 LPEP-----GAPARKPLQPDELSHPARPPSEPKSGAFPRK---LWQPEAGEATPRSPQPE 208
Query: 266 SSSEPEP-------VVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWK 309
S+ P+ V P+ P+ G K + + P+WK
Sbjct: 209 LSTFPKKPAQPEFNVYPKKPPQPQVGGLPK---KSVPQPEFSEAAQTPLWK 256
Score = 35.8 bits (81), Expect = 0.19
Identities = 58/225 (25%), Positives = 77/225 (34%), Gaps = 54/225 (24%)
Query: 56 PLPGFEDSPDQRRLPPEQESLSRLEQP----DLSSEMSKVSKPRASKPGRKRGGRTRKGP 111
P P D P ++ PPE L + P DL + SK+ SK + G P
Sbjct: 84 PPPEVTDLP-KKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPF--P 140
Query: 112 KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP 171
++P QP APL L + P P L E P RP
Sbjct: 141 RKPLQPEVGEAPLKASLPEPGAPARKP---------------------LQPDELSHPARP 179
Query: 172 PEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQP- 230
P E SG PR+ L+ E E + P P+ T PKK QP
Sbjct: 180 PS--EPKSGAFPRK-------LWQPEAGE----------ATPRSPQPELSTFPKKPAQPE 220
Query: 231 ----AACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPE 271
P +V G P+ Q E + ++ SSEP+
Sbjct: 221 FNVYPKKPPQPQVGGLPKKS--VPQPEFSEAAQTPLWKPQSSEPK 263
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 22/137 (16%)
Query: 56 PLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASK----PGRKRGGRTRKGP 111
P+P ++SP +LP E S +K ++P+A P + R+ P
Sbjct: 320 PIPNVQNSPIPAKLP---------EPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRP 370
Query: 112 KRPQ-QPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLL--------LKLSKDLDR 162
K Q QPNP P+ P L + P P+ G ++ LL S+ L +
Sbjct: 371 KAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQ 430
Query: 163 PESQSPKRPPEDFETPS 179
+++ P+ PP +TPS
Sbjct: 431 TQAKQPQAPPTPQQTPS 447
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/205 (25%), Positives = 78/205 (38%), Gaps = 32/205 (15%)
Query: 93 KPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLST---PMPKKRGRKSKA 149
+P P R G K K PQ PS PL +++PLST P+P K ++K
Sbjct: 538 QPPVGAPHRASGTSPLK-QKGPQGLGQPSGPLPA----KASPLSTKASPLPSKASPQAK- 591
Query: 150 ELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAP 209
P R E +TPS + ++ + + E +T PA
Sbjct: 592 ------------------PLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPE-TTPTPAT 632
Query: 210 VSCPEGPKVSSPTKPKKIRQPAACPGGEEVD--GAPRDEDFFLQVEA--EDVEESEGPSE 265
G + + P P P A GGE D G P +D ++ + S+G S
Sbjct: 633 PKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISS 692
Query: 266 SSSEPEPVVPRSTPRGSTSGKQKPH 290
S SE VV + + ++G PH
Sbjct: 693 SQSEITGVVQQEVEQLDSAGVTGPH 717
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/284 (21%), Positives = 103/284 (36%), Gaps = 45/284 (15%)
Query: 41 EMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPG 100
E +S + + P PG S + + PE +S L +P SE + ++P+A KP
Sbjct: 1721 EGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSE--EANEPKAEKPD 1778
Query: 101 RKRGGR---TRKGPKRPQQPNPPSAPL---VPGLLDQSNP-----------------LST 137
+K P+ P S L P P +
Sbjct: 1779 ATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEK 1838
Query: 138 PMPKKRGRKSKAEL-----------LLLKLSKDLDRPESQSPKRPPEDFETPSGERP--R 184
P+ +K R + +L LL+L + ++ + K D E P P R
Sbjct: 1839 PVTRKSERIDREKLKRSNSPRGEAQKLLELKMEAEKITRTASKNSAADLEHPEPSLPLSR 1898
Query: 185 RRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPR 244
R V +Y E + + PV E P+V+ +++++ AA P P+
Sbjct: 1899 TRRRNVRSVYATMGDHENRSPVKEPV---EQPRVTRKRLERELQEAAAVPTTPRRGRPPK 1955
Query: 245 DEDFFLQVEAEDVEESEGPSESSSEPEP-VVPRSTPRGSTSGKQ 287
+ + E+ E++ P+E+ PE PRS + G Q
Sbjct: 1956 TR---RRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQ 1996
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 42.0 bits (97), Expect = 0.003
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 538 VATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLS 597
VA V ++ CG L W P +HLA+G + +V W ++P
Sbjct: 297 VAEHHVATLSGHSQEVCG----LRWAPDG--RHLASGGNDNLVNVW---PSAP------- 340
Query: 598 DGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAG--SDRKIKFWDL 643
G P Q F H AV+ + WC S+ L + G SDR I+ W++
Sbjct: 341 -GEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNV 387
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 42.0 bits (97), Expect = 0.003
Identities = 79/325 (24%), Positives = 120/325 (36%), Gaps = 55/325 (16%)
Query: 26 PGQEVLNQLDVKTSSEMTSAEASVEMSLPTP-LPGFED--SPDQRRLPPEQESL-----S 77
P Q+V+ + TSS+ +A ++ P P +PG E+ SP +L SL
Sbjct: 806 PPQKVVAHTEFTTSSDSETANG---IAKPDPVMPGGEEKASPFGIKLRRTNYSLRFNCDQ 862
Query: 78 RLEQPDLSSEMSKVSKPRASKP--GRKRGGRT------RKGPKRPQQ-----------PN 118
+ EQ S A P G RG + + GP PQ+
Sbjct: 863 QAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAE 922
Query: 119 PPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP 178
P S+ VP P S+ P K+ ++ L + +P SQ+P P
Sbjct: 923 PSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQTPPASP------ 976
Query: 179 SGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEE 238
++++ YL EL LS P PE + S + R+P + PG EE
Sbjct: 977 --------LSKLSRPYLVEL---LSRRAGRPD--PEPSEPSKEDQESSDRRPPSPPGPEE 1023
Query: 239 VDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNG 298
G RDE + EA + + + P ++ + +P R Q H +
Sbjct: 1024 RKGQKRDE----EEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLT 1079
Query: 299 LPNHIMAPVWKCLHLTKD--FREQK 321
P+W L L K FREQ+
Sbjct: 1080 EKVETAQPLWITLALQKQKGFREQQ 1104
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 7/128 (5%)
Query: 120 PSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPS 179
P PL PG L P+ST MP + S S+ E + + E+ E+ S
Sbjct: 454 PDEPLEPGPL----PVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509
Query: 180 GERPRRRAAQVALL--YLQELAEELSTALPAPVSCPEGPKVSSPTKPK-KIRQPAACPGG 236
+ RA ++A L L+ + E+L+ P+S P+ + K K K + G
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569
Query: 237 EEVDGAPR 244
+E D PR
Sbjct: 570 DEDDKGPR 577
Score = 35.4 bits (80), Expect = 0.24
Identities = 72/307 (23%), Positives = 112/307 (36%), Gaps = 59/307 (19%)
Query: 37 KTSSEMTSAEASVEMSLPTPLPGFE-----------DSPDQR--RLPPEQESLSRLEQPD 83
K+SSE +S E+S E S E DS ++R RL QE L + +
Sbjct: 475 KSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQL 534
Query: 84 LSSEMSKVSKPRASKP--------------GRKRGGRTRKGPKRPQQPNPP--------- 120
+ +SKP+ + GR KGP+ P+ P P
Sbjct: 535 AALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSG 594
Query: 121 --SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLD--RPESQSPKRPPE-DF 175
SA L P S T +PKK + + L S++ + RP S KR D
Sbjct: 595 GGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDI 654
Query: 176 ETPSGERPRR-------RAAQVALLYLQELAEELSTALPAPVSCPEGPKVS----SPTKP 224
GE+ R R + +E+ + T P+ + E +S P KP
Sbjct: 655 NKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKP 714
Query: 225 KKIRQPA-------ACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRS 277
I++P A E++ +D L + +++ +ESSS + V R
Sbjct: 715 YTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRL 774
Query: 278 TPRGSTS 284
+ S+S
Sbjct: 775 SASSSSS 781
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 7/128 (5%)
Query: 120 PSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPS 179
P PL PG L P+ST MP + S S+ E + + E+ E+ S
Sbjct: 454 PDEPLEPGPL----PVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509
Query: 180 GERPRRRAAQVALL--YLQELAEELSTALPAPVSCPEGPKVSSPTKPK-KIRQPAACPGG 236
+ RA ++A L L+ + E+L+ P+S P+ + K K K + G
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569
Query: 237 EEVDGAPR 244
+E D PR
Sbjct: 570 DEDDKGPR 577
Score = 35.4 bits (80), Expect = 0.24
Identities = 72/307 (23%), Positives = 112/307 (36%), Gaps = 59/307 (19%)
Query: 37 KTSSEMTSAEASVEMSLPTPLPGFE-----------DSPDQR--RLPPEQESLSRLEQPD 83
K+SSE +S E+S E S E DS ++R RL QE L + +
Sbjct: 475 KSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQL 534
Query: 84 LSSEMSKVSKPRASKP--------------GRKRGGRTRKGPKRPQQPNPP--------- 120
+ +SKP+ + GR KGP+ P+ P P
Sbjct: 535 AALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSG 594
Query: 121 --SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLD--RPESQSPKRPPE-DF 175
SA L P S T +PKK + + L S++ + RP S KR D
Sbjct: 595 GGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDI 654
Query: 176 ETPSGERPRR-------RAAQVALLYLQELAEELSTALPAPVSCPEGPKVS----SPTKP 224
GE+ R R + +E+ + T P+ + E +S P KP
Sbjct: 655 NKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKP 714
Query: 225 KKIRQPA-------ACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRS 277
I++P A E++ +D L + +++ +ESSS + V R
Sbjct: 715 YTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRL 774
Query: 278 TPRGSTS 284
+ S+S
Sbjct: 775 SASSSSS 781
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/254 (20%), Positives = 95/254 (37%), Gaps = 24/254 (9%)
Query: 38 TSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRAS 97
+SS +S+ +S S + S P + E+P S+ S+ K
Sbjct: 163 SSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP---SKDSREHKSAFK 219
Query: 98 KPGRKRGGRTRKGPKRPQQPNP-PSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKL 156
+P R +++ K+P++ P +VP + P P + K + LL +
Sbjct: 220 EPSRDHNKSSKESSKKPKENKPLKEEKIVPKM-----AFKEPKPMSKEPKPDSNLLTITS 274
Query: 157 SKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGP 216
+D P KRPP + R++++ AL + S+A P ++C
Sbjct: 275 GQDKKAPS----KRPPISDSEELSAKKRKKSSSEALF------KSFSSAPPLILTCSADK 324
Query: 217 KV---SSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPV 273
K S K K++ + ++ P D+ + DVEE+ S +P P
Sbjct: 325 KQIKDKSHVKMGKVKIESETSEKKKSTLPPFDD--IVDPNDSDVEENISSKSDSEQPSPA 382
Query: 274 VPRSTPRGSTSGKQ 287
S+ S + Q
Sbjct: 383 SSSSSSSSSFTPSQ 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,175,119
Number of Sequences: 37866
Number of extensions: 2495205
Number of successful extensions: 12981
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 573
Number of HSP's that attempted gapping in prelim test: 11460
Number of HSP's gapped (non-prelim): 1996
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.