Guide to the Human Genome
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Search of human proteins with 4504205

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504205 general transcription factor IIIC, polypeptide 2,
beta 110kDa [Homo sapiens]
         (911 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|78482617 general transcription factor IIIC, polypeptide 2, be...  1893   0.0  
gi|4504205 general transcription factor IIIC, polypeptide 2, bet...  1893   0.0  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    51   6e-06
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    48   5e-05
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H...    47   8e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     47   8e-05
gi|148727255 microtubule associated serine/threonine kinase fami...    46   1e-04
gi|110349719 titin isoform N2-A [Homo sapiens]                         45   2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        45   2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             45   2e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          45   3e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          45   3e-04
gi|119943102 CREB binding protein isoform b [Homo sapiens]             45   4e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens]             45   4e-04
gi|4507703 tumor suppressing subtransferable candidate 1 [Homo s...    45   4e-04
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                44   5e-04
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  44   7e-04
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              43   0.001
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              43   0.001
gi|210032580 SET domain containing 1B [Homo sapiens]                   43   0.001
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]       43   0.002
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    43   0.002
gi|91208420 bassoon protein [Homo sapiens]                             42   0.002
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     42   0.003
gi|118402582 cell division cycle 20 [Homo sapiens]                     42   0.003
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              42   0.003
gi|164419758 bromodomain containing 2 [Homo sapiens]                   42   0.003
gi|4826806 bromodomain containing 2 [Homo sapiens]                     42   0.003
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    42   0.003

>gi|78482617 general transcription factor IIIC, polypeptide 2, beta
           110kDa [Homo sapiens]
          Length = 911

 Score = 1893 bits (4904), Expect = 0.0
 Identities = 911/911 (100%), Positives = 911/911 (100%)

Query: 1   MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60
           MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF
Sbjct: 1   MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60

Query: 61  EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120
           EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP
Sbjct: 61  EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120

Query: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180
           SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG
Sbjct: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180

Query: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240
           ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD
Sbjct: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240

Query: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
           GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP
Sbjct: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300

Query: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360
           NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV
Sbjct: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360

Query: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420
           QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS
Sbjct: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420

Query: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480
           PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA
Sbjct: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480

Query: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540
           WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT
Sbjct: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540

Query: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600
           LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS
Sbjct: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600

Query: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660
           LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE
Sbjct: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660

Query: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720
           LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI
Sbjct: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720

Query: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780
           AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN
Sbjct: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780

Query: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840
           PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV
Sbjct: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840

Query: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900
           RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF
Sbjct: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900

Query: 901 SPTSHRLLPTP 911
           SPTSHRLLPTP
Sbjct: 901 SPTSHRLLPTP 911


>gi|4504205 general transcription factor IIIC, polypeptide 2, beta
           110kDa [Homo sapiens]
          Length = 911

 Score = 1893 bits (4904), Expect = 0.0
 Identities = 911/911 (100%), Positives = 911/911 (100%)

Query: 1   MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60
           MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF
Sbjct: 1   MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGF 60

Query: 61  EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120
           EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP
Sbjct: 61  EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPP 120

Query: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180
           SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG
Sbjct: 121 SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSG 180

Query: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240
           ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD
Sbjct: 181 ERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVD 240

Query: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
           GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP
Sbjct: 241 GAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300

Query: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360
           NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV
Sbjct: 301 NHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSV 360

Query: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420
           QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS
Sbjct: 361 QREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSS 420

Query: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480
           PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA
Sbjct: 421 PDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGA 480

Query: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540
           WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT
Sbjct: 481 WELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVAT 540

Query: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600
           LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS
Sbjct: 541 LQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGS 600

Query: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660
           LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE
Sbjct: 601 LKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTE 660

Query: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720
           LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI
Sbjct: 661 LAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTI 720

Query: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780
           AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN
Sbjct: 721 AAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPN 780

Query: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840
           PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV
Sbjct: 781 PPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKV 840

Query: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900
           RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF
Sbjct: 841 RFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGF 900

Query: 901 SPTSHRLLPTP 911
           SPTSHRLLPTP
Sbjct: 901 SPTSHRLLPTP 911


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 88/343 (25%), Positives = 124/343 (36%), Gaps = 65/343 (18%)

Query: 58  PGFEDSPDQRRLPPEQESLSRLEQPDLSS-----EMSKVSKPRASKPGRKRGGRTRKGP- 111
           P FE+SP    L P  E L     P+ S      E S +S P    P       +R  P 
Sbjct: 547 PPFEESP----LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602

Query: 112 --KRPQQPNPPSAPLVP-------GLLDQSNPLSTPMPKKRGRKSKAE---LLLLKLSKD 159
             + P  P P  +PL P           + +P+S P P++       E   L  L +   
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSR 661

Query: 160 LDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALP---APVSCP--- 213
           L  P  +SP  PP + E+P+   P           L    E+  T+ P   +P S P   
Sbjct: 662 LSPPPEESPLSPPPE-ESPTSPPPEASR-------LSPPPEDSPTSPPPEDSPASPPPED 713

Query: 214 --------EGPKVSSPTKPK---KIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEG 262
                   E P +  P +P+   +   P   P  EE   +PR E+  L  +AE+   S  
Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773

Query: 263 PSESSSEPEPVVPRSTPRGSTSG-KQKPHCRGMAPNGLPNHIM-APVWKCL-------HL 313
           P E      P  P  +P+        +P    ++P     H+   P   CL       HL
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833

Query: 314 TKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSP 356
           +    E   S        P   + HL  ELE  P  P+ EK P
Sbjct: 834 SPQSEEPCLS--------PRPEESHLSPELEKPPLSPRPEKPP 868



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 72/269 (26%), Positives = 92/269 (34%), Gaps = 30/269 (11%)

Query: 13  EAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSP--DQRRLP 70
           EA P+G   V   P      QL+   + EM       E  L  P      SP  +  RL 
Sbjct: 415 EAKPLGKAGVQLEP------QLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLS 468

Query: 71  PEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLD 130
           P  E L     P    E   +S+P    P       +    + P  P P S+P  P  L+
Sbjct: 469 PPPEELPASPLP----EALHLSRPLEESP------LSPPPEESPLSPPPESSPFSP--LE 516

Query: 131 QSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQV 190
           +S PLS P         +  L     +  L  P  +SP  PP + E P+   P       
Sbjct: 517 ES-PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE-ELPTSPPPEASR--- 571

Query: 191 ALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFL 250
               L    EE S   P P   P  P   +        +    P  EE   +P  E   L
Sbjct: 572 ----LSPPPEE-SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626

Query: 251 QVEAEDVEESEGPSESSSEPEPVVPRSTP 279
               ED   S  P ES   P P V R +P
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSP 655



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 74/283 (26%), Positives = 105/283 (37%), Gaps = 45/283 (15%)

Query: 39  SSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
           +S ++       MS P         P+  RL P    +SRL  P    E S +S P    
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP-LPVVSRLSPPP---EESPLSPPPEES 678

Query: 99  PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
           P       +R  P  P + +P S P       + +P S P           E  LL L +
Sbjct: 679 PTSPPPEASRLSP--PPEDSPTSPP------PEDSPASPPPEDSLMSLPLEESPLLPLPE 730

Query: 159 DLDR-PESQSPK---RPPEDFETPSGERPRRRAAQVALLYLQELAEE--LSTALPAPVSC 212
           +    P S+ P    RP E   +P  E P          +L   AEE  LS     P  C
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEP----------HLSPQAEEPHLSPQPEEPCLC 780

Query: 213 --PEGPKVSSPTK-------PKKIR------QPAACPGGEEVDGAPRDEDFFLQVEAEDV 257
             PE P +S   +       P+++       +P   P  EE   +P+ E+  L  ++E+ 
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840

Query: 258 EESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
             S  P ES   PE   P  +PR     ++   C   AP  LP
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC--PAPEELP 881



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 60/258 (23%), Positives = 87/258 (33%), Gaps = 28/258 (10%)

Query: 48   SVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGR------ 101
            S E+  P   P  E  P++    P  E L     P   S    + +P  S+PG       
Sbjct: 852  SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911

Query: 102  ------KRGGRTRKGPK--RPQQPNPPSAPLV----PGLLDQSNPLSTPMPKKRGRKSKA 149
                     G     P+   P    PP +P++    P  L     L  P   K     ++
Sbjct: 912  PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPES 971

Query: 150  ELLLLKLSKDLDRPESQS---PKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTAL 206
             L    L   +  P   +   P+  P     PS   P   A+ + +  L      L    
Sbjct: 972  PLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031

Query: 207  PAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSES 266
              P + P   + S P  P  +  P + P G+ V     DE    ++E E V E E P   
Sbjct: 1032 LVPQNSPPS-QCSPPALPLSVPSPLS-PIGKVV--GVSDEAELHEMETEKVSEPECP--- 1084

Query: 267  SSEPEPVVPRSTPRGSTS 284
            + EP    P  +P G  S
Sbjct: 1085 ALEPSATSPLPSPMGDLS 1102



 Score = 33.9 bits (76), Expect = 0.71
 Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 4/106 (3%)

Query: 34   LDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSK 93
            LD+   +            L TP    +   +++ LP  Q+     + PD++ E S+  +
Sbjct: 1782 LDLSRKALFAVGVGRPSFGLGTPKAKGDGGSERKELPTSQKGD---DGPDIADEESRGLE 1838

Query: 94   PRASKPGRKRGG-RTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTP 138
             +A  PG + GG +    P  P++P  P   ++   LD+ +    P
Sbjct: 1839 GKADTPGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRISTEELP 1884


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 53/198 (26%), Positives = 80/198 (40%), Gaps = 32/198 (16%)

Query: 16  PVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMS-----LPTPLPGF--EDSPDQRR 68
           PV +MT V  P  +++   D   S E    +   +          P  GF  +D P    
Sbjct: 566 PVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGG-- 623

Query: 69  LPPEQESLSRLEQPDLSSEMSKVSKPRASK-PGRKRGGRTRKGPKRPQQPNPPSAPLVPG 127
              + + L+R        E  K  + +A K P   +  + +K PK P+ P  P  P  P 
Sbjct: 624 --VDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPK 681

Query: 128 LLDQSNPLSTPMPKKRGRKS------KAELLLLKLSK---------DLDRPESQSPKRPP 172
             ++    +TP PK   + S      +A  L  K++K         DLD+    SP  PP
Sbjct: 682 --EKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSP--PP 737

Query: 173 EDFETPSGERPRRRAAQV 190
           E+ E P G + RR + QV
Sbjct: 738 EEDEDP-GVQKRRSSRQV 754


>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
            sapiens]
          Length = 1447

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 65/279 (23%), Positives = 109/279 (39%), Gaps = 33/279 (11%)

Query: 36   VKTSSEMTSAEASVEMSLPTPL---PGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVS 92
            + + S   S E+  +  LP      P    S  +  LPPE +S     +P  ++ +  V+
Sbjct: 1076 IMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVN 1135

Query: 93   KP--RASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSN---------PLSTPMP- 140
            KP   A K  + +  R           NP S   + G LD S           +S+P+P 
Sbjct: 1136 KPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPG 1195

Query: 141  KKRGRKSKAELLLLKLSKDLDRPES----QSPKRPPEDF------ETPSG-ERPRRRAAQ 189
            KK  ++  ++L+  +L K   R ++    Q  K   +D       + P G +R R+R   
Sbjct: 1196 KKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHT 1255

Query: 190  VALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFF 249
             +    Q+  EE    L   +   E  + S P K K+ R P    G     G P++E   
Sbjct: 1256 ASESDEQQWPEE--KRLKEDILENEDEQNSPPKKGKRGRPPKPLGG-----GTPKEEPTM 1308

Query: 250  LQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQK 288
               +    ++S  P+    E E     +T + S S + +
Sbjct: 1309 KTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHR 1347


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 55/262 (20%), Positives = 102/262 (38%), Gaps = 29/262 (11%)

Query: 45  AEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRG 104
           AEA   +      P    SP++ + P ++E+ S   +   S E  +   P  +K   K  
Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS--PEKAKSPEKEEAKSPEKAKSPVKAE 673

Query: 105 GRTRKGPKRP--QQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKS--------KAELLLL 154
            ++ +  K P   +   P     P   +  +P     P K   KS        K E    
Sbjct: 674 AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733

Query: 155 KLSKDLDRPESQSPKRP--PE-----DFETPSGERPRRRAAQVALLYLQELAEELSTALP 207
           + +K   + E++SP++   PE     D ++P  + P +  A+       +  E+  + + 
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA---DKFPEKAKSPVK 790

Query: 208 APVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESS 267
             V  PE  K  SP K          P  EEV    ++E+     + ++V+  E P ++ 
Sbjct: 791 EEVKSPE--KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE-----KPQEVKVKEPPKKAE 843

Query: 268 SEPEPVVPRSTPRGSTSGKQKP 289
            E  P  P++  +  +  ++ P
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAP 865



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 48/213 (22%), Positives = 83/213 (38%), Gaps = 35/213 (16%)

Query: 64  PDQRRLPPEQESLSRLEQPDLS-SEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSA 122
           P +    PE+E+ S +++   S +E     K  A  P   +     K P + +  +PP A
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564

Query: 123 PL-----VPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFET 177
                       +  +P     P K   KS AE    + +K   + E++S    P + ++
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS----PAEAKS 620

Query: 178 PSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPK-KIRQPAACPGG 236
           P  E  +                      PA V  PE  K  SPTK + K  + A  P  
Sbjct: 621 PVKEEAKS---------------------PAEVKSPE--KAKSPTKEEAKSPEKAKSPEK 657

Query: 237 EEVDGAPRDEDFFLQVEAEDVEESEGPSESSSE 269
           EE   +P      ++ EA+  E+++ P ++ ++
Sbjct: 658 EEAK-SPEKAKSPVKAEAKSPEKAKSPVKAEAK 689



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 51/235 (21%), Positives = 89/235 (37%), Gaps = 19/235 (8%)

Query: 74  ESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSN 133
           E ++  E+ +   E  K  +    +   + G    K P   +  +P      P   +  +
Sbjct: 468 EEVTEEEEKEAKEEEGK-EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526

Query: 134 PLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALL 193
           P     P+K   KS AE   +K  +    P  +  K PPE  ++P  E  +  A   +  
Sbjct: 527 PAEAKSPEKEEAKSPAE---VKSPEKAKSPAKEEAKSPPE-AKSPEKEEAKSPAEVKSPE 582

Query: 194 YLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE 253
             +  A+E + + PA    PE  K  SP K ++ + PA          +P  E+     E
Sbjct: 583 KAKSPAKEEAKS-PAEAKSPE--KAKSPVK-EEAKSPAEAK-------SPVKEEAKSPAE 631

Query: 254 AEDVEESEGPS-ESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPV 307
            +  E+++ P+ E +  PE           +  K K   +  A +  P    +PV
Sbjct: 632 VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS--PEKAKSPV 684



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 52/263 (19%), Positives = 98/263 (37%), Gaps = 35/263 (13%)

Query: 46  EASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGG 105
           EA       +P+     SP++ + P + ++L  ++ P+  +   + ++  A K   K   
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD-VKSPEAKTPAKEEARSPADKFPEKAKS 787

Query: 106 RTRKGPKRPQQPNPP-----SAPL--VPGLLDQSNPLS---------TPMPKKRGRKSKA 149
             ++  K P++   P      AP   +P   +  +P+             P K+  + KA
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847

Query: 150 ELLLL----KLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTA 205
                    K SK  + P+ ++PK   E+ + P+ E+P+    +      +E AE+    
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK----KEEAEDKKKV 903

Query: 206 LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSE 265
                  P   +V    KPK+  + A     +E D A   E       ++  E+ E   E
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAK----KEPDDAKAKE------PSKPAEKKEAAPE 953

Query: 266 SSSEPEPVVPRSTPRGSTSGKQK 288
                E    +   +  T  K K
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAK 976


>gi|148727255 microtubule associated serine/threonine kinase family
            member 4 isoform a [Homo sapiens]
          Length = 2434

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 66/288 (22%), Positives = 100/288 (34%), Gaps = 50/288 (17%)

Query: 43   TSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPD--LSSEMSKVSKPRASKPG 100
            T+  +S     P P+    +S   +  P       + + PD  LSS+   V   +  +P 
Sbjct: 1980 TAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGATKGKEPA 2039

Query: 101  RKR-GGRTRKGPKRPQQPNPPSAPLVPGLLDQSN------------PLST--------PM 139
             +  GG +R+G K   +  P   P  PG  ++++            PL T        P 
Sbjct: 2040 TQSLGGSSREG-KGHSKSGPDVFPATPGSQNKASDGIGQGEGGPSVPLHTDRAPLDAKPQ 2098

Query: 140  PKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELA 199
            P   GR     L +L+    L RP    P  P +   +  GE+            L    
Sbjct: 2099 PTSGGRP----LEVLEKPVHLPRPGHPGPSEPADQKLSAVGEKQT----------LSPKH 2144

Query: 200  EELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVE- 258
             + ST    P  C +     +   P    QPAA       +G    E  +   E + +E 
Sbjct: 2145 PKPSTVKDCPTLCKQTDNRQTDKSPS---QPAANTD-RRAEGKKCTEALYAPAEGDKLEA 2200

Query: 259  -----ESEGPSESSSEPEPVVPRSTP--RGSTSGKQKPHCRGMAPNGL 299
                  SE   + +  P   V +  P  RG   G QKP      PNG+
Sbjct: 2201 GLSFVHSENRLKGAERPAAGVGKGFPEARGKGPGPQKPPTEADKPNGM 2248



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 48/182 (26%), Positives = 71/182 (39%), Gaps = 30/182 (16%)

Query: 14   AGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFE----DSPDQRRL 69
            +GP  + T + SP            S++  S    V  S+P  LP       D+   R L
Sbjct: 1622 SGPQASKTELPSP-----------ESAQSPSPSGDVRASVPPVLPSSSGKKNDTTSAREL 1670

Query: 70   PPEQESLSR---LEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVP 126
             P    +++   LE   L       + P  S P  +   R RKGP     P   S    P
Sbjct: 1671 SPSSLKMNKSYLLEPWFLPPSRGLQNSPAVSLPDPEFK-RDRKGP----HPTARS----P 1721

Query: 127  GLLDQSNPLSTP--MPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPR 184
            G + +SNP       PK +   +  +LL   L ++L  P+   P+ P     +PS E+P 
Sbjct: 1722 GTVMESNPQQREGSSPKHQDHTTDPKLLTC-LGQNLHSPDLARPRCPLPPEASPSREKPG 1780

Query: 185  RR 186
             R
Sbjct: 1781 LR 1782



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 49/216 (22%), Positives = 77/216 (35%), Gaps = 29/216 (13%)

Query: 82   PDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPK 141
            PD  ++   + K  A  PG K   +   G  RP  P   S+    G+     P    + K
Sbjct: 1834 PDFYTQTQAMEKAWA--PGGKTNHKDGPGEARPP-PRDNSSLHSAGI-----PCEKELGK 1885

Query: 142  -KRGRKSKAELLLLKLSKDLDRPESQSPKRPPE--DFETPSGERPRRRAAQVALLYLQEL 198
             +RG + K E LL + S      ES+  ++       +    + P R+         Q L
Sbjct: 1886 VRRGVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKE--------QPL 1937

Query: 199  AEELSTALPAPV-----SCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE 253
                S+  P P+     S P   +  S       R+P A P   E   +P+D    +   
Sbjct: 1938 QRHPSSIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAKPSTAEPSSSPQDPPKPVAAH 1997

Query: 254  AEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKP 289
            +E       P      P+P  P++     +   QKP
Sbjct: 1998 SESSSHKPRPG-----PDPGPPKTKHPDRSLSSQKP 2028


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 60/234 (25%), Positives = 93/234 (39%), Gaps = 50/234 (21%)

Query: 64    PDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAP 123
             P++ R+PP              +++ +V  P+   P +K      K P+ P    PP  P
Sbjct: 10485 PEEPRVPP--------------TKVPEVLPPKEVVPEKKVPVPPAKKPEAP----PPKVP 10526

Query: 124   LVPGLLDQSNPLSTPMPKKRG-------RKSKAELLLLKLSKDLDRPESQSPKRPPEDFE 176
               P  +     +  P PKK            KA +   K+ + +  P+ +SP  PPE  E
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP-PKPESP--PPEVPE 10583

Query: 177   TPSGERPRRRAA-------QVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKI-- 227
              P    P ++         +V  + + E  +E+      PV  P+ P+V  PTK  ++  
Sbjct: 10584 APKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP-PTKVPEVPK 10642

Query: 228   ------RQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVP 275
                   + P A P   E   +P  E F    E E+V   E P+E   EPEP  P
Sbjct: 10643 VAVPEKKVPEAIPPKPE---SPPPEVF---EEPEEVALEEPPAEVVEEPEPAAP 10690



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 65/287 (22%), Positives = 109/287 (37%), Gaps = 44/287 (15%)

Query: 23    VDSPGQEVLNQLDV-KTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQ 81
             V  P +EV   + V +   E+   E + E  + T +  +    ++  +  E+E ++  E 
Sbjct: 9883  VPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV 9942

Query: 82    ----PDLSSEMSKVSKPRASKP---GRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNP 134
                 P    E+ +   P   KP    +K+     K P+ P++P      L+P   ++  P
Sbjct: 9943  VPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK-EKPPP 10001

Query: 135   LSTP-MPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP-----SGERPRRRAA 188
                P +PKK   + K  + + K  +       + PK+P  + + P       E P  +  
Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061

Query: 189   QVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEV--------- 239
             +V    + E  E+  T +P  V  P  PKV  P K + +  P A P  EEV         
Sbjct: 10062 EVPKKLIPE--EKKPTPVPKKVEAPP-PKV--PKKREPVPVPVALPQEEEVLFEEEIVPE 10116

Query: 240   ---------------DGAPRDEDFFLQVEAEDVEESEGPSESSSEPE 271
                            +  P +E+   + E    EE E P E    PE
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE 10163



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 46/222 (20%), Positives = 83/222 (37%), Gaps = 23/222 (10%)

Query: 28    QEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFED--------SPDQRRLPPEQESLSRL 79
             +EVL + ++    E+   E  V       LP  E+         P++  +PPE+E +   
Sbjct: 10105 EEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEE 10164

Query: 80    EQPDLSSEMSKVSKPRASKPG------RKRGGRTRKGPKRPQQPNPPSAPLVPGLLD--- 130
             E+     E+    KP+   P       +K   +    PK+ + P P   P VP  ++   
Sbjct: 10165 EEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP-PAKVPEVPKKVEEKR 10223

Query: 131   -----QSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRR 185
                  +   L   + ++   +  +E  + +    ++  E  +P R PE  +    E P  
Sbjct: 10224 IILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTP 10283

Query: 186   RAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKI 227
                +V     +   +     +P PV   E P    P  PKK+
Sbjct: 10284 VPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKV 10325



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 52/244 (21%), Positives = 88/244 (36%), Gaps = 34/244 (13%)

Query: 58    PGFEDSPDQRR-LPPEQESLSRLEQPDLSSEMSKV---------SKPRASKPGRKRGGRT 107
             P  E +P++ + +P  +E    +  P +  E  K+          KP A  P      + 
Sbjct: 10812 PEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871

Query: 108   RKGPKRPQQPNPPSAPLVPGLLDQSNPL-------STPMPKKRGRKSKAELLLLKLSKDL 160
              + PK   +P PP  P  P   D    +          +P+K     K EL  LK+    
Sbjct: 10872 IEKPKLKPRPPPP--PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGE 10929

Query: 161   DRPESQSPKRPPEDFE-----TPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEG 215
              +     P+R PE  E     +   +RP     +V    L+++ +      P P    E 
Sbjct: 10930 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 10989

Query: 216   PKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVP 275
                +   + +KI +P   P   E+  A       + + A + +        + +P PV P
Sbjct: 10990 EVPTVTKRERKIPEPTKVP---EIKPA-------IPLPAPEPKPKPEAEVKTIKPPPVEP 11039

Query: 276   RSTP 279
               TP
Sbjct: 11040 EPTP 11043



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 51/220 (23%), Positives = 83/220 (37%), Gaps = 33/220 (15%)

Query: 50    EMSLPTPLPGFEDSPDQRRLP-PEQESLSR-----LEQPDLSSEMSKVSKPRASKPGRKR 103
             E  +P  +P   +SP       PE+ +L       +E+P+ ++       P+   P +K 
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKA 10706

Query: 104   GGRTRKGPKRP--QQPNPPS-------APLVPGLLDQSNPLSTP------MPKKR-GRKS 147
                  K P+ P  + P  P         PLV     ++ P   P      +P+K+     
Sbjct: 10707 PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766

Query: 148   KAELLLLKLSKDLDRPESQS------PKR----PPEDFETPSGERPRRRAAQVALLYLQE 197
             K E+   K+ +   +P  +       P+R    PPE +E P    P    A      +  
Sbjct: 10767 KPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP- 10825

Query: 198   LAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGE 237
             +AEE    +P P    E  K+    K   I++P A P  E
Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKE 10865


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 56/189 (29%), Positives = 64/189 (33%), Gaps = 27/189 (14%)

Query: 61  EDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPK-------- 112
           E SP  RR P     L R     LSS  + +S P  S P  +   R    P         
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 269

Query: 113 --RPQQPNPPSAPLVPGLLD-QSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPK 169
             RP Q  PP     P L    S+PL+TP P      S    L     + L  P    P 
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL-----QTLPSP----PA 320

Query: 170 RPPEDFETPSGERPRRRAAQVALLY--LQELAEELSTALPA----PVSCPEGPKVSSPTK 223
            PP    T  G  P  +A    L    L  LA     A PA    P+  P  P  S P  
Sbjct: 321 TPPSQATTSLGS-PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379

Query: 224 PKKIRQPAA 232
           P     P A
Sbjct: 380 PLATPSPQA 388



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 66/279 (23%), Positives = 90/279 (32%), Gaps = 62/279 (22%)

Query: 39  SSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
           +S   S  A+     P PL      P Q   PP Q   +    P     +  +  P AS 
Sbjct: 448 ASPPMSPSATPPPQAPPPLAA---PPLQLAKPPPQAPPALATPP-----LQALPSPPASF 499

Query: 99  PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
           PG+     +   P  P    PP AP V        P S P                    
Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA------------------- 540

Query: 159 DLDRPESQSPKRPPEDFETPSGERPRRRAAQV------------ALLYLQELAEELSTAL 206
               P  Q+P+RPP      S   PR   A              + L   +LA   S+A 
Sbjct: 541 ---SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597

Query: 207 PAPV------SCPEGPKVSSPTKPKKI---------RQPAACPGGEEVDGAPRDEDFFLQ 251
             P       S PEG   +SP    ++         R PA         GAP        
Sbjct: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657

Query: 252 VEAED----VEESEGPSESSSEPEPVVPRSTPRGSTSGK 286
             + D    + E+EGP  ++  P  + P  +P G++ GK
Sbjct: 658 PGSADGLCTIYETEGPESATPAPGALDPGPSP-GTSGGK 695


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 38/293 (12%)

Query: 34   LDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLP--------PEQESLSRLEQPDLS 85
            LD+K  S  +S  +S E+S          S      P        P +E  S    P++ 
Sbjct: 1369 LDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMK 1428

Query: 86   SEMSKVSKPRA---SKPGRKRGGRTRK----GPKRPQQPNPPSAPLVPGLLDQSNPL--- 135
              + +    R+   S PG + G  T          P   + P  P        S+P    
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKA 1488

Query: 136  --STPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALL 193
               TP P+ R   S  EL    L+   +R  S+S         TP G+R R  ++Q   +
Sbjct: 1489 LPQTPRPRSRS-PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547

Query: 194  YLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDG----APRDEDFF 249
                  +E S +  +P S     K  +P     +RQ +      EVD     +PR     
Sbjct: 1548 KPSASPQERSESDSSPDS---KAKTRTP-----LRQRSRSGSSPEVDSKSRLSPRRSRSG 1599

Query: 250  LQVEAED----VEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNG 298
               E +D       ++  S+SS EP+   PR+ PR S SG      RG +P G
Sbjct: 1600 SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG-RGPSPEG 1651



 Score = 37.4 bits (85), Expect = 0.064
 Identities = 57/259 (22%), Positives = 93/259 (35%), Gaps = 24/259 (9%)

Query: 45   AEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRG 104
            ++A   +SL   L G    P Q+   P + S S   QP   S         +S P  K+ 
Sbjct: 767  SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQK 826

Query: 105  GRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPM-------PKKRGRKSKAELLLLKLS 157
             +T    ++    + P   +  G   +   +++P        P++R     +    LK S
Sbjct: 827  SKTPS--RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK-S 883

Query: 158  KDLDRPESQSPKRPPEDFETPSGERPRRRAA---QVALLYLQELAEELSTALPAPVSCPE 214
            +   R        P     TP  + P R ++   +V  +          ++ P+P     
Sbjct: 884  RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP----- 938

Query: 215  GPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSS---EPE 271
              +V+S T P++ R  + C    E    PR            V+    P +S S    P 
Sbjct: 939  -SRVTSRTTPRRSRSVSPC-SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996

Query: 272  PVVPRSTPRG-STSGKQKP 289
            P V   TP G S SG + P
Sbjct: 997  PKVKAQTPPGPSLSGSKSP 1015



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 14/162 (8%)

Query: 38   TSSEMTSAEASVEMSL---PTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKP 94
            + SE +S     E++L   P+P P  +++  + R PPE     R  +   SS  S  S  
Sbjct: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR-PPEPTPAKRKRRSSSSSSSSSSSSS 2619

Query: 95   RASKPGRKRGGRTRKGPKRPQQPNPPSA---PLVPG---LLDQSNPLSTPMPKKRGRKSK 148
             +S         +          +  S+   P  PG   L   ++P   P  ++R R  +
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR 2679

Query: 149  AELLLLKLSKDLDRPESQ----SPKRPPEDFETPSGERPRRR 186
              +  L+ S+ L     +    SP+  P D ++ S ER  RR
Sbjct: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 48/242 (19%), Positives = 86/242 (35%), Gaps = 35/242 (14%)

Query: 54  PTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKR 113
           P P     +S   R   P+Q+   + +     SE S   + R  K  +K+  R+    K+
Sbjct: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRER-KKSSKKKKHRSESESKK 226

Query: 114 PQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPE 173
            +  +P                 TP  K++ +  K +    +       P+S+   R   
Sbjct: 227 RKHRSP-----------------TPKSKRKSKDKKRK----RSRSTTPAPKSRRAHRSTS 265

Query: 174 DFETPSGERPRRRAAQVALLYLQELAEELSTAL----PAPVSCPEGPKVSSPTKP--KKI 227
                S +  R R+   A       A+  +TAL    P+P S   G   +  ++P     
Sbjct: 266 ADSASSSDTSRSRSRSAA-------AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST 318

Query: 228 RQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQ 287
           ++P++     +   +P ++    + E      S  P  SS+ PEP  P         G  
Sbjct: 319 QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378

Query: 288 KP 289
           +P
Sbjct: 379 QP 380



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 57/269 (21%), Positives = 86/269 (31%), Gaps = 30/269 (11%)

Query: 38   TSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKV----SK 93
            + S MTS  A      P+P      +P Q  LPP Q+   R   P   S+ S+     + 
Sbjct: 2415 SQSRMTSERA------PSPSSRMGQAPSQSLLPPAQDQ-PRSPVPSAFSDQSRCLIAQTT 2467

Query: 94   PRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGL--LDQSNPLSTPMPKKRGRKSKAEL 151
            P A       G                S P  PG+   D   P     P   G +  + L
Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVP-APGVPHSDVGEP-----PASTGAQQPSAL 2521

Query: 152  LLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTAL---PA 208
              L+ +K+     S S         + S        +  +      L  +   AL   P+
Sbjct: 2522 AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS 2581

Query: 209  PVSCP-----EG-PKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEG 262
            P   P     EG P   +P K K+    ++         +           +     S  
Sbjct: 2582 PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641

Query: 263  PSESSSEPEPVV--PRSTPRGSTSGKQKP 289
             S SSS P P    P++ P+ ++  K  P
Sbjct: 2642 SSSSSSSPSPAKPGPQALPKPASPKKPPP 2670


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 57/261 (21%), Positives = 96/261 (36%), Gaps = 37/261 (14%)

Query: 38   TSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRAS 97
            +++ +TS+ A      PTP+     +P    +      L+    P L+S ++  S P  +
Sbjct: 1824 SAAAITSSSAPASAPAPTPILASVSTPASVTI------LASASIPILASALASTSAPTPA 1877

Query: 98   KPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLS 157
                         P  P      S PL P       P  TP+               +  
Sbjct: 1878 PAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTH 1937

Query: 158  KDLDRP---ESQSPKRPPEDFETPSG---------------ERPRRRAAQVALLYLQELA 199
            K +  P    SQS K+PP     PS                + P+      A L+  ++A
Sbjct: 1938 KPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVA 1997

Query: 200  -----EELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEA 254
                  ++S  L  P+S P+ P VS+  KP  +    + P  E   GA   ++  L++  
Sbjct: 1998 PPAVLNDISKKL-GPISPPQPPSVSAWNKP--LTSFGSAPSSE---GAKNGQESGLEIGT 2051

Query: 255  EDVEESEGPSESSSEPEPVVP 275
            + ++    P+ + +E E VVP
Sbjct: 2052 DTIQFG-APASNGNENE-VVP 2070



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 61/264 (23%), Positives = 107/264 (40%), Gaps = 27/264 (10%)

Query: 32   NQLDVKTSSEMT--SAEASVEMSLPTPL----PGFEDSPDQRRL--PPEQESLSRLEQPD 83
            NQL+    ++    S+EA V+  L   +    P   D+ +Q      P+Q++LS  ++  
Sbjct: 852  NQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEER 911

Query: 84   LSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTP--MPK 141
            +S+  S+ S+ R+   G      T+K  ++  +P+     +    +D   P+  P   PK
Sbjct: 912  ISAVESQPSRKRSVSHG---SNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPK 968

Query: 142  KRGR-KSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAE 200
            K G  +S       K+ K   + E++   RP  +      +RP RR+  +    L+++ E
Sbjct: 969  KEGFIRSSEGPKPEKVYKS--KSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKE 1026

Query: 201  ELSTALPAPVSCPEGPKVSSPTKPKKIRQ----PAACPGGEEVDGAPRDEDFFLQVEAED 256
            E            E        KP+K  +    P   P        P+     +Q EAE 
Sbjct: 1027 EREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEK 1086

Query: 257  VEESE------GPSESSSEP-EPV 273
               +E       PS+ + +P EPV
Sbjct: 1087 FPSTETATLAQKPSQDTEKPLEPV 1110



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 16/111 (14%)

Query: 94   PRASKPGRKRGGRTRKGPKRPQ-QPNPPSAPLVPGLLD-QSNPLSTPMPKKR-GRKSKAE 150
            P+     R RGG  R+G + P  +P+ PS    P   D Q NP  + +PK   G   +  
Sbjct: 1335 PKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRH 1394

Query: 151  LLLLKLSKDL-------------DRPESQSPKRPPEDFETPSGERPRRRAA 188
               + ++ D              +RP  Q P RPP   + P   R R R A
Sbjct: 1395 EQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREA 1445



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 24/106 (22%)

Query: 95   RASKPGRKRGGR--TRKGPK----RPQQPNPPSAPLVPGLLDQSNPLSTP---MPKKRGR 145
            R S  GR RGGR  TR  P+    +P+  + PS PL      ++   S+    +PK+R +
Sbjct: 1201 RGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQ 1260

Query: 146  K---------------SKAELLLLKLSKDLDRPESQSPKRPPEDFE 176
            +                K  L   KL K  +RPE++ P +P   F+
Sbjct: 1261 RGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFK 1306


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 66/278 (23%), Positives = 104/278 (37%), Gaps = 31/278 (11%)

Query: 21   TVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSP-DQRRLPPEQESLSRL 79
            T  D P  +V +Q + KT+  + +  A    S P    G + SP D + +P        +
Sbjct: 774  TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT--GEKVSPFDSKAIPRPASDSKII 831

Query: 80   EQPDLSSEMS--KVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQS----- 132
              P  SSE    K   P   K   K+  +T+  PK   +P P  +P  PG    +     
Sbjct: 832  SHPGPSSESKGQKQVDPVQKKEEPKKA-QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890

Query: 133  NPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVAL 192
             P  +P P+++ R+       L L    D P+SQ    P    ET +G     +      
Sbjct: 891  TPQQSPKPQEQSRR-----FSLNLGSITDAPKSQ----PTTPQETVTG-----KLFGFGA 936

Query: 193  LYLQELAEELSTA-LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQ 251
                + +  +STA  P P S   GP       P   + P +    +    AP      + 
Sbjct: 937  SIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIP 995

Query: 252  VEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKP 289
            V+    +E++ P+    EP+     +  R  T  K  P
Sbjct: 996  VK----KETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 59/262 (22%), Positives = 89/262 (33%), Gaps = 37/262 (14%)

Query: 54  PTPLPGFEDSPDQR---RLPPEQESLSRLEQ-----PDLSSEMSKVSKPRASKPGRKRGG 105
           P   PG    P Q      PP Q++ S         P   ++   V K  A +PG  +  
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411

Query: 106 RTRKGPKRP--QQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRP 163
             + G  +P  QQP   S    PG      P+  P P K   +               +P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469

Query: 164 ESQ--SPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSP 221
            SQ   P +PP     P+   P++  +       +  +++  +  P P     GP   SP
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSA------KPPSQQPGSTKPPPQQ--PGPAKPSP 521

Query: 222 TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRG 281
            +P   + P+  PG  +                   ++S  P   +   +P+ P   P  
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSP------AKPSAQQSTKPVSQTGSGKPLQP---PTV 572

Query: 282 STSGKQKPHCRGMAPNGLPNHI 303
           S S KQ P        GLP  I
Sbjct: 573 SPSAKQPP------SQGLPKTI 588



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 18/135 (13%)

Query: 43  TSAEASVEMSLPTPLPGFEDSPDQR----RLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
           TSA+ +     P+ LPG    P Q+    + PP+Q            S      +P ++K
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----------GSAKPPSQQPGSTK 508

Query: 99  PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
           P  ++ G  +  P++P    PPS    PG    S    +P  K   ++S   +      K
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQPSP-AKPSAQQSTKPVSQTGSGK 565

Query: 159 DLDRPE-SQSPKRPP 172
            L  P  S S K+PP
Sbjct: 566 PLQPPTVSPSAKQPP 580



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 63/290 (21%), Positives = 102/290 (35%), Gaps = 64/290 (22%)

Query: 48  SVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRT 107
           SV+ SLP+P       P   + P +Q    +             S+P  +KP  +  G T
Sbjct: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK-------------SQPGPAKPPAQPSGLT 339

Query: 108 RKGPKRPQQPN----------PPSAPLVPG------------LLDQSNPLSTPMPKKRGR 145
           +   ++P              PP+ PL P               +Q  P +   P   G+
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399

Query: 146 -------KSKAELLLLKLSKDL-DRPESQSPKRPPEDFETP-----SGERPRRRAAQVAL 192
                   +K     +   K L  +P  QSP + P   +TP      G+ P ++A     
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459

Query: 193 LYLQELAEELSTALPAPVSCP---EGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFF 249
              Q    +  + LP P   P    GP    P +P   + P+  PG  +    P  +   
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK---PPPQQPGP 516

Query: 250 LQVEAEDVEESEGPSE-------SSSEPEPVVP---RSTPRGSTSGKQKP 289
            +   +    ++ PS+       S+ +P P  P   +ST   S +G  KP
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 57   LPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQ 116
            LP  EDS ++  L  E+E L   E+     E+ +  +  +SK  +K     R   +R + 
Sbjct: 1767 LPTIEDSSEEEELREEEELLKEQEK---QREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823

Query: 117  PNPPS 121
              PPS
Sbjct: 1824 KTPPS 1828


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 66/278 (23%), Positives = 104/278 (37%), Gaps = 31/278 (11%)

Query: 21   TVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSP-DQRRLPPEQESLSRL 79
            T  D P  +V +Q + KT+  + +  A    S P    G + SP D + +P        +
Sbjct: 774  TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT--GEKVSPFDSKAIPRPASDSKII 831

Query: 80   EQPDLSSEMS--KVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQS----- 132
              P  SSE    K   P   K   K+  +T+  PK   +P P  +P  PG    +     
Sbjct: 832  SHPGPSSESKGQKQVDPVQKKEEPKKA-QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890

Query: 133  NPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVAL 192
             P  +P P+++ R+       L L    D P+SQ    P    ET +G     +      
Sbjct: 891  TPQQSPKPQEQSRR-----FSLNLGSITDAPKSQ----PTTPQETVTG-----KLFGFGA 936

Query: 193  LYLQELAEELSTA-LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQ 251
                + +  +STA  P P S   GP       P   + P +    +    AP      + 
Sbjct: 937  SIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIP 995

Query: 252  VEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKP 289
            V+    +E++ P+    EP+     +  R  T  K  P
Sbjct: 996  VK----KETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 59/262 (22%), Positives = 89/262 (33%), Gaps = 37/262 (14%)

Query: 54  PTPLPGFEDSPDQR---RLPPEQESLSRLEQ-----PDLSSEMSKVSKPRASKPGRKRGG 105
           P   PG    P Q      PP Q++ S         P   ++   V K  A +PG  +  
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411

Query: 106 RTRKGPKRP--QQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRP 163
             + G  +P  QQP   S    PG      P+  P P K   +               +P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469

Query: 164 ESQ--SPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSP 221
            SQ   P +PP     P+   P++  +       +  +++  +  P P     GP   SP
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSA------KPPSQQPGSTKPPPQQ--PGPAKPSP 521

Query: 222 TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRG 281
            +P   + P+  PG  +                   ++S  P   +   +P+ P   P  
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSP------AKPSAQQSTKPVSQTGSGKPLQP---PTV 572

Query: 282 STSGKQKPHCRGMAPNGLPNHI 303
           S S KQ P        GLP  I
Sbjct: 573 SPSAKQPP------SQGLPKTI 588



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 18/135 (13%)

Query: 43  TSAEASVEMSLPTPLPGFEDSPDQR----RLPPEQESLSRLEQPDLSSEMSKVSKPRASK 98
           TSA+ +     P+ LPG    P Q+    + PP+Q            S      +P ++K
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----------GSAKPPSQQPGSTK 508

Query: 99  PGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSK 158
           P  ++ G  +  P++P    PPS    PG    S    +P  K   ++S   +      K
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQPSP-AKPSAQQSTKPVSQTGSGK 565

Query: 159 DLDRPE-SQSPKRPP 172
            L  P  S S K+PP
Sbjct: 566 PLQPPTVSPSAKQPP 580



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 63/290 (21%), Positives = 102/290 (35%), Gaps = 64/290 (22%)

Query: 48  SVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRT 107
           SV+ SLP+P       P   + P +Q    +             S+P  +KP  +  G T
Sbjct: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK-------------SQPGPAKPPAQPSGLT 339

Query: 108 RKGPKRPQQPN----------PPSAPLVPG------------LLDQSNPLSTPMPKKRGR 145
           +   ++P              PP+ PL P               +Q  P +   P   G+
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399

Query: 146 -------KSKAELLLLKLSKDL-DRPESQSPKRPPEDFETP-----SGERPRRRAAQVAL 192
                   +K     +   K L  +P  QSP + P   +TP      G+ P ++A     
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459

Query: 193 LYLQELAEELSTALPAPVSCP---EGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFF 249
              Q    +  + LP P   P    GP    P +P   + P+  PG  +    P  +   
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK---PPPQQPGP 516

Query: 250 LQVEAEDVEESEGPSE-------SSSEPEPVVP---RSTPRGSTSGKQKP 289
            +   +    ++ PS+       S+ +P P  P   +ST   S +G  KP
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 57   LPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQ 116
            LP  EDS ++  L  E+E L   E+     E+ +  +  +SK  +K     R   +R + 
Sbjct: 1767 LPTIEDSSEEEELREEEELLKEQEK---QREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823

Query: 117  PNPPS 121
              PPS
Sbjct: 1824 KTPPS 1828


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 55/233 (23%), Positives = 81/233 (34%), Gaps = 23/233 (9%)

Query: 52   SLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGP 111
            +LP PL        Q   PP  +S      P  S+     S    + PG           
Sbjct: 790  ALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT--------- 840

Query: 112  KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP 171
              P QP  P+ P  P       P  TP       ++++   +   ++    P+ Q+P +P
Sbjct: 841  --PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP 898

Query: 172  PEDFETP--SGERPRRRAAQVALLYLQELAEELSTALPAPVSCPE--------GPKVSSP 221
            P    TP  S ++P    AQ     L + A  +   +P P S           GP V   
Sbjct: 899  P-SVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVL 957

Query: 222  TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE-AEDVEESEGPSESSSEPEPV 273
                + +     P   E  G PR E     ++ A  V+E    +E  SEP  V
Sbjct: 958  EMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEV 1010



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 48/197 (24%), Positives = 70/197 (35%), Gaps = 35/197 (17%)

Query: 72   EQESLSRLEQPDLS----SEMSKVSKPRASKPGRKRG--GRTRKGPKRPQQPNPPSAPLV 125
            +Q+   RL+Q  L     + M+  + P+ S P       G   + P  PQ P PP+ P  
Sbjct: 1814 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-- 1871

Query: 126  PGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP----SGE 181
                 Q +P+S       G  S A       +    +P SQ P  PP     P    +  
Sbjct: 1872 -----QPSPVSM---SPAGFPSVAR-TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAAR 1922

Query: 182  RPRRRAAQVALLYLQELAEEL-----------STALPAPVSCPEGPKVSSPTKPKKIR-- 228
            +  R A Q   LY   +   +           S   P  ++ P   +VS P  P      
Sbjct: 1923 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ 1982

Query: 229  -QPAACPGGEEVDGAPR 244
             Q A  P  + + G PR
Sbjct: 1983 WQQAPLPQQQPMPGLPR 1999



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 718  GTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSG 777
            G   A  + G+ IA  L +   +P  V+ P  +  P + +     Q  P  P H S  +G
Sbjct: 2285 GQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPS-PHHVSPQTG 2343

Query: 778  VPNPPKARTYTETVNHHYL 796
             P+P  A T   +++  +L
Sbjct: 2344 SPHPGLAVTMASSIDQGHL 2362


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 55/233 (23%), Positives = 81/233 (34%), Gaps = 23/233 (9%)

Query: 52   SLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGP 111
            +LP PL        Q   PP  +S      P  S+     S    + PG           
Sbjct: 828  ALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT--------- 878

Query: 112  KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP 171
              P QP  P+ P  P       P  TP       ++++   +   ++    P+ Q+P +P
Sbjct: 879  --PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP 936

Query: 172  PEDFETP--SGERPRRRAAQVALLYLQELAEELSTALPAPVSCPE--------GPKVSSP 221
            P    TP  S ++P    AQ     L + A  +   +P P S           GP V   
Sbjct: 937  P-SVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVL 995

Query: 222  TKPKKIRQPAACPGGEEVDGAPRDEDFFLQVE-AEDVEESEGPSESSSEPEPV 273
                + +     P   E  G PR E     ++ A  V+E    +E  SEP  V
Sbjct: 996  EMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEV 1048



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 48/197 (24%), Positives = 70/197 (35%), Gaps = 35/197 (17%)

Query: 72   EQESLSRLEQPDLS----SEMSKVSKPRASKPGRKRG--GRTRKGPKRPQQPNPPSAPLV 125
            +Q+   RL+Q  L     + M+  + P+ S P       G   + P  PQ P PP+ P  
Sbjct: 1852 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-- 1909

Query: 126  PGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP----SGE 181
                 Q +P+S       G  S A       +    +P SQ P  PP     P    +  
Sbjct: 1910 -----QPSPVSM---SPAGFPSVAR-TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAAR 1960

Query: 182  RPRRRAAQVALLYLQELAEEL-----------STALPAPVSCPEGPKVSSPTKPKKIR-- 228
            +  R A Q   LY   +   +           S   P  ++ P   +VS P  P      
Sbjct: 1961 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ 2020

Query: 229  -QPAACPGGEEVDGAPR 244
             Q A  P  + + G PR
Sbjct: 2021 WQQAPLPQQQPMPGLPR 2037



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 718  GTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSG 777
            G   A  + G+ IA  L +   +P  V+ P  +  P + +     Q  P  P H S  +G
Sbjct: 2323 GQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPS-PHHVSPQTG 2381

Query: 778  VPNPPKARTYTETVNHHYL 796
             P+P  A T   +++  +L
Sbjct: 2382 SPHPGLAVTMASSIDQGHL 2400


>gi|4507703 tumor suppressing subtransferable candidate 1 [Homo
           sapiens]
          Length = 387

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 2/58 (3%)

Query: 611 AHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYN 668
           AH Q VR L +     ++L S G D K+KFWD R   EP+ +++    +   W + YN
Sbjct: 226 AHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEE--HSHWVWNVRYN 281


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 26/201 (12%)

Query: 40  SEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKP 99
           S + S  +    S P+ LP  +  P+  + PPE    S L  P    E      P  S  
Sbjct: 623 SSLQSPVSICSSSTPSSLP--QSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPE 680

Query: 100 GRKRGGRTRKGPKRPQQP----------NPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKA 149
               G  +    + PQ P          + P +P  P   D  +PL  P    +G   ++
Sbjct: 681 SAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSP--PEWEDSLSPLHFPQFPPQGEDFQS 738

Query: 150 ELL----LLKLSKDLDRPES--QSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELS 203
            L     +   S  L  P+S  +SP+ PPE       +RP      V+  +   LA  L 
Sbjct: 739 SLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRP------VSSFFSYTLASLLQ 792

Query: 204 TALPAPVSCPEGPKVSSPTKP 224
           ++  +P S PEGP  S    P
Sbjct: 793 SSHESPQSPPEGPAQSPLQSP 813



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 5/123 (4%)

Query: 53  LPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPK 112
           +P+ L    +SP     P  ++S S L+ P  S E      P  S   R  G  +    +
Sbjct: 11  MPSLLQSSSESPQS--CPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEGEDSSDPLQ 68

Query: 113 RPQQPNPPSAPL-VPGLLDQSNPLSTPMPKKRGR-KSKAELLLLKLSKDLDRPES-QSPK 169
           RP +     +PL +P    + +   +P+   +   + K  L  L++S+     E  QSP 
Sbjct: 69  RPPEGKDSQSPLQIPQSSPEGDDTQSPLQNSQSSPEGKDSLSPLEISQSPPEGEDVQSPL 128

Query: 170 RPP 172
           + P
Sbjct: 129 QNP 131


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 80/339 (23%), Positives = 120/339 (35%), Gaps = 54/339 (15%)

Query: 9    VALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRR 68
            V L  A P G +    SP Q + + L V++ +   S   S  M++P+P  G+  SP    
Sbjct: 962  VPLPSANPPGPLK---SP-QVLGSSLSVRSPTGSPSRLKSPSMAVPSP--GWVASPKTAM 1015

Query: 69   LPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQP---NPPSAPLV 125
              P    +S+ +QP L+   S       +    ++G     GP+        NPPS  + 
Sbjct: 1016 PSP---GVSQNKQPPLNMNSS------TTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMN 1066

Query: 126  PGLLDQSNPLSTP----------------MPKKRGRKSKAELLLLKLSKDLDRPESQSPK 169
            P L   S+P  TP                MP        A   +     +L       P 
Sbjct: 1067 PSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPP 1126

Query: 170  RPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCP---EGPKVSSPTKPKK 226
             PP     P G  P    +Q + ++L   A +    +  P   P   E P    P+    
Sbjct: 1127 PPP-----PQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPL 1181

Query: 227  IRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPR-STPRGSTS- 284
                   P  +   G P++         + +    GP  SSS+  P  PR   P G+ + 
Sbjct: 1182 GSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAP 1241

Query: 285  --------GKQKPHCRGMA--PNGLPNHIMAPVWKCLHL 313
                    G Q+ +  GMA  P  LPN    P+    HL
Sbjct: 1242 TGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHL 1280


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 73/340 (21%), Positives = 109/340 (32%), Gaps = 65/340 (19%)

Query: 16  PVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPE--- 72
           PVG  +++     +  +QLD +       A   V+ +        ED  D      E   
Sbjct: 300 PVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHR 359

Query: 73  -QESLSRLEQPDLSSEMSKVSKPRASKPGRK-------RGGRTRKGPKRPQQP------- 117
             +S S  E+P   ++  K + P +  P  K       R   T  GP  P+ P       
Sbjct: 360 DSQSASGEERPP-EADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRG 418

Query: 118 ---------------NPPSAPLVPGLLDQ---------SNPLSTPMPKKRGRKSKAELLL 153
                           PP  P  P   D+         S+ +S  + + R R+ + E   
Sbjct: 419 PAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEE--- 475

Query: 154 LKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCP 213
            ++ ++     ++  KR  E F  P        AA  A          +   LPAP   P
Sbjct: 476 RRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAP---P 532

Query: 214 EGPKVSSPTKPKKIRQPAACPGGEEV-------------DGAPRDEDFFLQVEAEDVEES 260
             P  S+PT   +  +PA  P  +                G           EA  VE  
Sbjct: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ 592

Query: 261 EGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLP 300
               E    PE V P +TP      K +P   G+ P   P
Sbjct: 593 LPSKEGPEPPEEVPPPTTP---PVPKVEPKGDGIGPTRQP 629



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 9/131 (6%)

Query: 13  EAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPT---PLPGFEDSPDQRRL 69
           EA PV    +    G E   ++   T+  +   E   +   PT   P  G      Q+ L
Sbjct: 585 EASPV-EPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSL 643

Query: 70  PP-----EQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPL 124
           PP     +QE L + +Q     +  + S P    P       T      PQ P PP   L
Sbjct: 644 PPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKAL 703

Query: 125 VPGLLDQSNPL 135
            PG L +  P+
Sbjct: 704 YPGALGRPPPM 714



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 57/254 (22%), Positives = 82/254 (32%), Gaps = 45/254 (17%)

Query: 50   EMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRK 109
            ++ L  P PG   SP   R                ++   +V  PR     R RGG    
Sbjct: 1134 QVPLAPPPPGAPPSPAPARF---------------TARGGRVFTPRGVPSRRGRGGG--- 1175

Query: 110  GPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPK 169
              + P Q  P  +P    L  +  P     P K   K K  L+   LS     P ++   
Sbjct: 1176 --RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEK--LIPGPLS-----PVARGGS 1226

Query: 170  RPPEDFETPSGERPRRR-----AAQVALLYLQELAEELSTA-----------LPAPVSCP 213
                +     GERPRRR       Q      + L +E   A           LPA    P
Sbjct: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP 1286

Query: 214  EGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPV 273
            E    +    P   R  A  P     +    +E++    E+ D        + +  P  +
Sbjct: 1287 EEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLL 1346

Query: 274  VPRS--TPRGSTSG 285
             P++  TP G   G
Sbjct: 1347 TPKAVGTPGGGGGG 1360


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 51/255 (20%), Positives = 99/255 (38%), Gaps = 26/255 (10%)

Query: 66   QRRLPPEQESLSR--LEQPDLS-SEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSA 122
            +++ PP ++  S+  L  PD   + + +  +P    PG +       GPK P+  N P  
Sbjct: 915  KKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL--PGEQGINLDNSGPKLPEFSNRP-- 970

Query: 123  PLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGER 182
            P  P    +  PL    P+     +       +  +   +P+    ++PP   +  S ++
Sbjct: 971  PGYPSQPVEQRPLQQMPPQLMQHVAPPP----QPPQQQPQPQLPQQQQPPPPSQPQSQQQ 1026

Query: 183  PRRRAAQVALLYLQELAEELSTALPAPVSCPEGP-KVSSPTKPKK----------IRQPA 231
             +++   + +L +Q+  + +   +   V  P GP    S   P +          ++ PA
Sbjct: 1027 QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPA 1086

Query: 232  ACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHC 291
            + P   +    P   +  L   +  +   E P   SS P   +         SG + P  
Sbjct: 1087 SVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSP---LAEMASLPEASGSEAPSV 1143

Query: 292  RGMAPNGLPNHIMAP 306
             G  PN +P+H++ P
Sbjct: 1144 PG-GPNNMPSHVVLP 1157



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 37/161 (22%), Positives = 59/161 (36%), Gaps = 26/161 (16%)

Query: 64   PDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAP 123
            P Q++ PP  +  S+ +Q      M  +   +  K  R             Q  +PP  P
Sbjct: 1010 PQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVS---------QNVHPPRGP 1060

Query: 124  LVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERP 183
            L        NP S  MP ++   S +  +++ L      P S   +R P    TP G   
Sbjct: 1061 L--------NPDSQRMPMQQ---SGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109

Query: 184  RRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKP 224
            R+      ++Y +      S+ L    S PE     +P+ P
Sbjct: 1110 RK------MVYQESPQNPSSSPLAEMASLPEASGSEAPSVP 1144


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 50/187 (26%), Positives = 69/187 (36%), Gaps = 29/187 (15%)

Query: 13   EAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPE 72
            EA        VDS G E   ++D++T  E  + E    M    PLP   + P   R PPE
Sbjct: 1172 EAALAPGAPAVDSLGME--EEVDIET--EAVAPEERPSMLDEPPLPVGVEEPADSREPPE 1227

Query: 73   QESLSR----LEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKR------------PQQ 116
            +  LS+    L  P+  ++  +   P + +   +        P              P+ 
Sbjct: 1228 EPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRP 1287

Query: 117  PNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFE 176
            P PPS P  P   D S+P   P P           L   L+K      SQS +  P    
Sbjct: 1288 PRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAK------SQSTETVP---A 1338

Query: 177  TPSGERP 183
            TP GE P
Sbjct: 1339 TPGGEPP 1345



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 47/181 (25%), Positives = 63/181 (34%), Gaps = 41/181 (22%)

Query: 53   LPTPL----PGFEDSPDQ-RRLPPEQESLSR-LEQPDLSSEMSK---------------- 90
            LP PL    P  +  P + RR PP   SL   L +P   + + +                
Sbjct: 1461 LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520

Query: 91   VSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAP-------LVPGLLDQSNPLSTPMPKKR 143
               PR      +  G     P  P QP PP  P       L    LD   P     P  R
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580

Query: 144  GRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGE----------RPRRRAAQVALL 193
            GR    E   ++L+K    P  + PK+  ED   P+G           RPR    ++ +L
Sbjct: 1581 GRDEVTE-EYMELAKSRG-PWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTIL 1638

Query: 194  Y 194
            Y
Sbjct: 1639 Y 1639


>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
          Length = 669

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 66/291 (22%), Positives = 100/291 (34%), Gaps = 60/291 (20%)

Query: 36  VKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQE--SLSRLEQPDLSSEMSKVSK 93
           +++  +  S +A  + S P P        D  + PP+ E   L +  QP+LS    K   
Sbjct: 9   MESHQDFRSIKAKFQASQPEP-------SDLPKKPPKPEFGKLKKFSQPELSEHPKKAPL 61

Query: 94  PR----ASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSN----PLSTPMPKKRGR 145
           P     + KP         K P  P+  + P  P  P + D       P  T +PKK   
Sbjct: 62  PEFGAVSLKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKK--- 118

Query: 146 KSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTA 205
              ++L L  LSK    P+  +   P +  +   GE P                  L  +
Sbjct: 119 --PSKLELSDLSKKF--PQLGATPFPRKPLQPEVGEAP------------------LKAS 156

Query: 206 LPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSE 265
           LP P     G     P +P ++  PA  P   +    PR      Q EA +        E
Sbjct: 157 LPEP-----GAPARKPLQPDELSHPARPPSEPKSGAFPRK---LWQPEAGEATPRSPQPE 208

Query: 266 SSSEPEP-------VVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWK 309
            S+ P+        V P+  P+    G  K   + +           P+WK
Sbjct: 209 LSTFPKKPAQPEFNVYPKKPPQPQVGGLPK---KSVPQPEFSEAAQTPLWK 256



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 58/225 (25%), Positives = 77/225 (34%), Gaps = 54/225 (24%)

Query: 56  PLPGFEDSPDQRRLPPEQESLSRLEQP----DLSSEMSKVSKPRASKPGRKRGGRTRKGP 111
           P P   D P ++  PPE   L +   P    DL  + SK+     SK   + G      P
Sbjct: 84  PPPEVTDLP-KKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPF--P 140

Query: 112 KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP 171
           ++P QP    APL   L +   P   P                     L   E   P RP
Sbjct: 141 RKPLQPEVGEAPLKASLPEPGAPARKP---------------------LQPDELSHPARP 179

Query: 172 PEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQP- 230
           P   E  SG  PR+       L+  E  E          + P  P+    T PKK  QP 
Sbjct: 180 PS--EPKSGAFPRK-------LWQPEAGE----------ATPRSPQPELSTFPKKPAQPE 220

Query: 231 ----AACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPE 271
                  P   +V G P+      Q E  +  ++      SSEP+
Sbjct: 221 FNVYPKKPPQPQVGGLPKKS--VPQPEFSEAAQTPLWKPQSSEPK 263


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 22/137 (16%)

Query: 56  PLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASK----PGRKRGGRTRKGP 111
           P+P  ++SP   +LP         E    S   +K ++P+A      P  +     R+ P
Sbjct: 320 PIPNVQNSPIPAKLP---------EPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRP 370

Query: 112 KRPQ-QPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLL--------LKLSKDLDR 162
           K  Q QPNP   P+ P L  +      P P+  G  ++  LL            S+ L +
Sbjct: 371 KAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQ 430

Query: 163 PESQSPKRPPEDFETPS 179
            +++ P+ PP   +TPS
Sbjct: 431 TQAKQPQAPPTPQQTPS 447


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 53/205 (25%), Positives = 78/205 (38%), Gaps = 32/205 (15%)

Query: 93  KPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLST---PMPKKRGRKSKA 149
           +P    P R  G    K  K PQ    PS PL      +++PLST   P+P K   ++K 
Sbjct: 538 QPPVGAPHRASGTSPLK-QKGPQGLGQPSGPLPA----KASPLSTKASPLPSKASPQAK- 591

Query: 150 ELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAP 209
                             P R  E  +TPS  + ++         + +   E +T  PA 
Sbjct: 592 ------------------PLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPE-TTPTPAT 632

Query: 210 VSCPEGPKVSSPTKPKKIRQPAACPGGEEVD--GAPRDEDFFLQVEA--EDVEESEGPSE 265
                G + + P  P     P A  GGE  D  G P  +D     ++  +    S+G S 
Sbjct: 633 PKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISS 692

Query: 266 SSSEPEPVVPRSTPRGSTSGKQKPH 290
           S SE   VV +   +  ++G   PH
Sbjct: 693 SQSEITGVVQQEVEQLDSAGVTGPH 717


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 61/284 (21%), Positives = 103/284 (36%), Gaps = 45/284 (15%)

Query: 41   EMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPG 100
            E +S +    +    P PG   S  +  + PE +S   L +P   SE  + ++P+A KP 
Sbjct: 1721 EGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSE--EANEPKAEKPD 1778

Query: 101  RKRGGR---TRKGPKRPQQPNPPSAPL---VPGLLDQSNP-----------------LST 137
                      +K    P+   P S  L    P       P                 +  
Sbjct: 1779 ATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEK 1838

Query: 138  PMPKKRGRKSKAEL-----------LLLKLSKDLDRPESQSPKRPPEDFETPSGERP--R 184
            P+ +K  R  + +L            LL+L  + ++    + K    D E P    P  R
Sbjct: 1839 PVTRKSERIDREKLKRSNSPRGEAQKLLELKMEAEKITRTASKNSAADLEHPEPSLPLSR 1898

Query: 185  RRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPR 244
             R   V  +Y      E  + +  PV   E P+V+     +++++ AA P        P+
Sbjct: 1899 TRRRNVRSVYATMGDHENRSPVKEPV---EQPRVTRKRLERELQEAAAVPTTPRRGRPPK 1955

Query: 245  DEDFFLQVEAEDVEESEGPSESSSEPEP-VVPRSTPRGSTSGKQ 287
                  + + E+  E++ P+E+   PE    PRS    +  G Q
Sbjct: 1956 TR---RRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQ 1996


>gi|118402582 cell division cycle 20 [Homo sapiens]
          Length = 499

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)

Query: 538 VATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLS 597
           VA   V ++       CG    L W P    +HLA+G  + +V  W    ++P       
Sbjct: 297 VAEHHVATLSGHSQEVCG----LRWAPDG--RHLASGGNDNLVNVW---PSAP------- 340

Query: 598 DGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAG--SDRKIKFWDL 643
            G     P Q F  H  AV+ + WC   S+ L + G  SDR I+ W++
Sbjct: 341 -GEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNV 387


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 79/325 (24%), Positives = 120/325 (36%), Gaps = 55/325 (16%)

Query: 26   PGQEVLNQLDVKTSSEMTSAEASVEMSLPTP-LPGFED--SPDQRRLPPEQESL-----S 77
            P Q+V+   +  TSS+  +A     ++ P P +PG E+  SP   +L     SL      
Sbjct: 806  PPQKVVAHTEFTTSSDSETANG---IAKPDPVMPGGEEKASPFGIKLRRTNYSLRFNCDQ 862

Query: 78   RLEQPDLSSEMSKVSKPRASKP--GRKRGGRT------RKGPKRPQQ-----------PN 118
            + EQ       S      A  P  G  RG +       + GP  PQ+             
Sbjct: 863  QAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAE 922

Query: 119  PPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETP 178
            P S+  VP       P S+  P     K+  ++ L +      +P SQ+P   P      
Sbjct: 923  PSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQTPPASP------ 976

Query: 179  SGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEE 238
                     ++++  YL EL   LS     P   PE  + S   +    R+P + PG EE
Sbjct: 977  --------LSKLSRPYLVEL---LSRRAGRPD--PEPSEPSKEDQESSDRRPPSPPGPEE 1023

Query: 239  VDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNG 298
              G  RDE    + EA + + +  P  ++ + +P       R      Q  H    +   
Sbjct: 1024 RKGQKRDE----EEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLT 1079

Query: 299  LPNHIMAPVWKCLHLTKD--FREQK 321
                   P+W  L L K   FREQ+
Sbjct: 1080 EKVETAQPLWITLALQKQKGFREQQ 1104


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 7/128 (5%)

Query: 120 PSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPS 179
           P  PL PG L    P+ST MP    + S         S+     E +  +   E+ E+ S
Sbjct: 454 PDEPLEPGPL----PVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509

Query: 180 GERPRRRAAQVALL--YLQELAEELSTALPAPVSCPEGPKVSSPTKPK-KIRQPAACPGG 236
            +    RA ++A L   L+ + E+L+     P+S P+  +     K K K  +     G 
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569

Query: 237 EEVDGAPR 244
           +E D  PR
Sbjct: 570 DEDDKGPR 577



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 72/307 (23%), Positives = 112/307 (36%), Gaps = 59/307 (19%)

Query: 37  KTSSEMTSAEASVEMSLPTPLPGFE-----------DSPDQR--RLPPEQESLSRLEQPD 83
           K+SSE +S E+S E S        E           DS ++R  RL   QE L  + +  
Sbjct: 475 KSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQL 534

Query: 84  LSSEMSKVSKPRASKP--------------GRKRGGRTRKGPKRPQQPNPP--------- 120
            +     +SKP+  +               GR       KGP+ P+ P P          
Sbjct: 535 AALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSG 594

Query: 121 --SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLD--RPESQSPKRPPE-DF 175
             SA L P     S    T +PKK  + +   L     S++ +  RP S   KR    D 
Sbjct: 595 GGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDI 654

Query: 176 ETPSGERPRR-------RAAQVALLYLQELAEELSTALPAPVSCPEGPKVS----SPTKP 224
               GE+  R       R   +     +E+  +  T  P+ +   E   +S     P KP
Sbjct: 655 NKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKP 714

Query: 225 KKIRQPA-------ACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRS 277
             I++P        A     E++   +D    L    +  +++   +ESSS  +  V R 
Sbjct: 715 YTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRL 774

Query: 278 TPRGSTS 284
           +   S+S
Sbjct: 775 SASSSSS 781


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 7/128 (5%)

Query: 120 PSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPS 179
           P  PL PG L    P+ST MP    + S         S+     E +  +   E+ E+ S
Sbjct: 454 PDEPLEPGPL----PVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509

Query: 180 GERPRRRAAQVALL--YLQELAEELSTALPAPVSCPEGPKVSSPTKPK-KIRQPAACPGG 236
            +    RA ++A L   L+ + E+L+     P+S P+  +     K K K  +     G 
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569

Query: 237 EEVDGAPR 244
           +E D  PR
Sbjct: 570 DEDDKGPR 577



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 72/307 (23%), Positives = 112/307 (36%), Gaps = 59/307 (19%)

Query: 37  KTSSEMTSAEASVEMSLPTPLPGFE-----------DSPDQR--RLPPEQESLSRLEQPD 83
           K+SSE +S E+S E S        E           DS ++R  RL   QE L  + +  
Sbjct: 475 KSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQL 534

Query: 84  LSSEMSKVSKPRASKP--------------GRKRGGRTRKGPKRPQQPNPP--------- 120
            +     +SKP+  +               GR       KGP+ P+ P P          
Sbjct: 535 AALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSG 594

Query: 121 --SAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLD--RPESQSPKRPPE-DF 175
             SA L P     S    T +PKK  + +   L     S++ +  RP S   KR    D 
Sbjct: 595 GGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDI 654

Query: 176 ETPSGERPRR-------RAAQVALLYLQELAEELSTALPAPVSCPEGPKVS----SPTKP 224
               GE+  R       R   +     +E+  +  T  P+ +   E   +S     P KP
Sbjct: 655 NKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKP 714

Query: 225 KKIRQPA-------ACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRS 277
             I++P        A     E++   +D    L    +  +++   +ESSS  +  V R 
Sbjct: 715 YTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRL 774

Query: 278 TPRGSTS 284
           +   S+S
Sbjct: 775 SASSSSS 781


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 53/254 (20%), Positives = 95/254 (37%), Gaps = 24/254 (9%)

Query: 38  TSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRAS 97
           +SS  +S+ +S   S  +       S       P +      E+P   S+ S+  K    
Sbjct: 163 SSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP---SKDSREHKSAFK 219

Query: 98  KPGRKRGGRTRKGPKRPQQPNP-PSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKL 156
           +P R     +++  K+P++  P     +VP +         P P  +  K  + LL +  
Sbjct: 220 EPSRDHNKSSKESSKKPKENKPLKEEKIVPKM-----AFKEPKPMSKEPKPDSNLLTITS 274

Query: 157 SKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGP 216
            +D   P     KRPP         + R++++  AL       +  S+A P  ++C    
Sbjct: 275 GQDKKAPS----KRPPISDSEELSAKKRKKSSSEALF------KSFSSAPPLILTCSADK 324

Query: 217 KV---SSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPV 273
           K     S  K  K++  +     ++    P D+   +     DVEE+      S +P P 
Sbjct: 325 KQIKDKSHVKMGKVKIESETSEKKKSTLPPFDD--IVDPNDSDVEENISSKSDSEQPSPA 382

Query: 274 VPRSTPRGSTSGKQ 287
              S+   S +  Q
Sbjct: 383 SSSSSSSSSFTPSQ 396


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,175,119
Number of Sequences: 37866
Number of extensions: 2495205
Number of successful extensions: 12981
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 573
Number of HSP's that attempted gapping in prelim test: 11460
Number of HSP's gapped (non-prelim): 1996
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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