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Search of human proteins with 4503993
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503993 growth hormone receptor precursor [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503993 growth hormone receptor precursor [Homo sapiens] 1316 0.0
gi|4506107 prolactin receptor [Homo sapiens] 160 4e-39
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 56 9e-08
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 44 3e-04
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 44 3e-04
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 42 0.002
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 42 0.002
gi|4885491 myeloproliferative leukemia virus oncogene precursor ... 39 0.019
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 39 0.019
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 38 0.025
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 38 0.025
gi|110349719 titin isoform N2-A [Homo sapiens] 37 0.043
gi|110349717 titin isoform novex-2 [Homo sapiens] 37 0.043
gi|110349713 titin isoform novex-1 [Homo sapiens] 37 0.043
gi|110349715 titin isoform N2-B [Homo sapiens] 37 0.043
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 37 0.056
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 37 0.056
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 37 0.056
gi|119220552 sidekick 1 [Homo sapiens] 35 0.21
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 35 0.28
gi|22212918 ciliary neurotrophic factor receptor preproprotein [... 34 0.36
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H... 34 0.36
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 34 0.36
gi|166362732 ELK1 protein [Homo sapiens] 33 0.62
gi|166362730 ELK1 protein [Homo sapiens] 33 0.62
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi... 33 0.80
gi|102469034 janus kinase 1 [Homo sapiens] 33 1.1
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 33 1.1
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 33 1.1
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 33 1.1
>gi|4503993 growth hormone receptor precursor [Homo sapiens]
Length = 638
Score = 1316 bits (3405), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE 60
MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
Sbjct: 1 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE 60
Query: 61 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS 120
RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
Sbjct: 61 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS 120
Query: 121 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN 180
IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
Sbjct: 121 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN 180
Query: 181 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY 240
ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
Sbjct: 181 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY 240
Query: 241 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP 300
GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
Sbjct: 241 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP 300
Query: 301 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES 360
VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES
Sbjct: 301 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES 360
Query: 361 DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE 420
DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE
Sbjct: 361 DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE 420
Query: 421 ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS 480
ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS
Sbjct: 421 ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS 480
Query: 481 LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA 540
LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA
Sbjct: 481 LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA 540
Query: 541 KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI 600
KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI
Sbjct: 541 KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI 600
Query: 601 VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP 638
VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
Sbjct: 601 VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP 638
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 160 bits (404), Expect = 4e-39
Identities = 115/357 (32%), Positives = 175/357 (49%), Gaps = 37/357 (10%)
Query: 50 EPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGE 109
+P+ KCRSP +ETF+C W GT G + Y+ +E ECPDY++ G
Sbjct: 30 KPEIFKCRSPNKETFTCWWRP----GTD--GGLPTNYSLTYHREGETLMHECPDYITGGP 83
Query: 110 NSCYFNSSFTSIWIPY--CIKLTSNGGT--VDEKCFSVDEIVQPDPPIALNWTLLNVSLT 165
NSC+F +TS+W Y + T+ G+ DE V IVQPDPP+ L +
Sbjct: 84 NSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDR 143
Query: 166 GIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKE 225
+ + ++W P D++ GW L YE++ K +W++ T + SL ++
Sbjct: 144 KPY--LWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQK 201
Query: 226 YEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLI-IIFGIFGLTVMLFV 284
Y V+VR K + G + +S ++ +P S FT + W+ + ++ + L ++ V
Sbjct: 202 YLVQVRCKP-DHGYWSAWSPATFIQIP--SDFTMNDTTV--WISVAVLSAVICLIIVWAV 256
Query: 285 FLFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVE 344
L K + I PPVP PKIKG D LL++GK EE+ + L D + P +D VE
Sbjct: 257 AL--KGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD-FPPTSDYEDLLVE 313
Query: 345 FIELDIDEPDEKTEESDTDRLLSSDHEKSHSNLGVK------DGDSGRTSCCEPDIL 395
++E+D E D+ L S H K H + G+K D DSGR SC P +L
Sbjct: 314 YLEVDDSE----------DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL 360
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 56.2 bits (134), Expect = 9e-08
Identities = 46/216 (21%), Positives = 95/216 (43%), Gaps = 22/216 (10%)
Query: 49 KEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAG 108
++P C S + +C WT H T + Y+ + W + C +Y + G
Sbjct: 136 EKPVNISCWSKNMKDLTCRWTPGAHGETF----LHTNYSLKYKLRWYGQDNTCEEYHTVG 191
Query: 109 ENSCYFNSSFTSIWIPY--CIKLTSNGGTVDEKCFSVD--EIVQPDPPIALNWTLLNVSL 164
+SC+ +++ PY ++ T+ G+ ++D ++V DPP ++ + +
Sbjct: 192 PHSCHIPKDL-ALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVG--- 247
Query: 165 TGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT-TSVPVYSLKVD 223
G+ + VRW +P ++ +Y+++Y+ + WK++D + TS + LK
Sbjct: 248 -GLEDQLSVRWVSP--PALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPG 304
Query: 224 KEYEVRVRSK------QRNSGNYGEFSEVLYVTLPQ 253
Y V+VR + +G + E+S + P+
Sbjct: 305 TVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPR 340
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 44.3 bits (103), Expect = 3e-04
Identities = 58/271 (21%), Positives = 111/271 (40%), Gaps = 36/271 (13%)
Query: 45 TNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDY 104
T ++ E +++ RS + + C W GT Q F R WT+E +E
Sbjct: 135 TTNTTEDNYSRLRSYQ-VSLHCTWLV----GTDAPEDTQYFLYYRYGS-WTEECQEYSKD 188
Query: 105 VSAGENSCYFNSSFTSI----WIPYCIKLTSNGGTVD--EKCFSVDEIVQPDPPIALNWT 158
+C+F +F W+ + +S + ++ F++ I Q +PP
Sbjct: 189 TLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPP------ 242
Query: 159 LLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVY 218
LNV+ + ++WE P +A + + ++ + K N + L T+ +
Sbjct: 243 -LNVTAEIEGTRLSIQWEKPVSA-----FPIHCFDYEVKIHNTRNGYLQIEKLMTNAFIS 296
Query: 219 SLKVDKEYEVRVR----SKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFG 274
+ +Y+V+VR S R +G + E+S+ +YV + W +I+I
Sbjct: 297 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLR-------EWFVIVIMA 349
Query: 275 IFGLTVMLFVFLFSKQQRIKMLILPPVPVPK 305
++L + L K + + + PP+P PK
Sbjct: 350 TICF-ILLILSLICKICHLWIKLFPPIPAPK 379
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 44.3 bits (103), Expect = 3e-04
Identities = 58/271 (21%), Positives = 111/271 (40%), Gaps = 36/271 (13%)
Query: 45 TNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDY 104
T ++ E +++ RS + + C W GT Q F R WT+E +E
Sbjct: 135 TTNTTEDNYSRLRSYQ-VSLHCTWLV----GTDAPEDTQYFLYYRYGS-WTEECQEYSKD 188
Query: 105 VSAGENSCYFNSSFTSI----WIPYCIKLTSNGGTVD--EKCFSVDEIVQPDPPIALNWT 158
+C+F +F W+ + +S + ++ F++ I Q +PP
Sbjct: 189 TLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPP------ 242
Query: 159 LLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVY 218
LNV+ + ++WE P +A + + ++ + K N + L T+ +
Sbjct: 243 -LNVTAEIEGTRLSIQWEKPVSA-----FPIHCFDYEVKIHNTRNGYLQIEKLMTNAFIS 296
Query: 219 SLKVDKEYEVRVR----SKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFG 274
+ +Y+V+VR S R +G + E+S+ +YV + W +I+I
Sbjct: 297 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLR-------EWFVIVIMA 349
Query: 275 IFGLTVMLFVFLFSKQQRIKMLILPPVPVPK 305
++L + L K + + + PP+P PK
Sbjct: 350 TICF-ILLILSLICKICHLWIKLFPPIPAPK 379
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/244 (22%), Positives = 92/244 (37%), Gaps = 34/244 (13%)
Query: 5 QLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETF 64
QLLL L L S SG + A L+ P ++ +S+ P
Sbjct: 4 QLLLALVLWASCPPCSGRKGPPAALTL---------PRVQCRASRYPI----------AV 44
Query: 65 SCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIP 124
C WT + + P+ T R C SC P
Sbjct: 45 DCSWT--LPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTS-TSCTITDVQLFSMAP 101
Query: 125 YCIKLTSN---GGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNA 181
Y + +T+ G + F + I++PDPP + + L +QV+WE P +
Sbjct: 102 YVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPL------AERQLQVQWEPPGSW 155
Query: 182 DIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYG 241
+ + L+Y ++YK ++ + PI TS + +++ Y V+V ++ +YG
Sbjct: 156 PFPEIFS-LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLT--DYG 212
Query: 242 EFSE 245
E S+
Sbjct: 213 ELSD 216
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 12/116 (10%)
Query: 142 SVDEIVQPD------PPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ 195
S+DEI+ D PP + V++ G H+ + V W+ D+ G++V Y
Sbjct: 1639 SLDEIIPNDLKKSDLPPQHAPRNITVVAVEGCHSFVIVDWDKATPGDVVTGYLV--YSAS 1696
Query: 196 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFS-EVLYVT 250
Y++ KW + T +P+ +LK + Y +V++ +N YG S V +VT
Sbjct: 1697 YEDFIRNKWSTQASSV-THLPIENLKPNTRYYFKVQA--QNPHGYGPISPSVSFVT 1749
>gi|4885491 myeloproliferative leukemia virus oncogene precursor
[Homo sapiens]
Length = 635
Score = 38.5 bits (88), Expect = 0.019
Identities = 53/268 (19%), Positives = 106/268 (39%), Gaps = 44/268 (16%)
Query: 55 KCRSPERETFSCHWTDEVH--------HGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVS 106
+C + + + +C W + H H P + N +E E K P +
Sbjct: 290 QCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYPIWENCEE---EEKTNPGLQT 346
Query: 107 AGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKC---FSVDEIVQPDPPIALNWTLLNVS 163
+ C+F S SI I +++T+ GTV F + + V+ P L+W ++
Sbjct: 347 PQFSRCHFKSRNDSI-IHILVEVTTAPGTVHSYLGSPFWIHQAVRLPTP-NLHWREIS-- 402
Query: 164 LTGIHADIQVRWEAPRNADIQKGWMVLE--YELQYKEVNETKWKMMDPILTTSVPVYSLK 221
+++ W+ P + W E Y+L+Y WK+++P L L+
Sbjct: 403 ----SGHLELEWQHPSS------WAAQETCYQLRYTGEGHQDWKVLEPPLGARGGTLELR 452
Query: 222 VDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLII--IFGIFGLT 279
Y +++R++ G +S T + + T W+ ++ + + GL+
Sbjct: 453 PRSRYRLQLRARLNGPTYQGPWSSWSDPTRVETATETA-------WISLVTALHLVLGLS 505
Query: 280 VMLFVFLFSKQ-----QRIKMLILPPVP 302
+L + L Q +R++ + P +P
Sbjct: 506 AVLGLLLLRWQFPAHYRRLRHALWPSLP 533
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 38.5 bits (88), Expect = 0.019
Identities = 43/180 (23%), Positives = 70/180 (38%), Gaps = 22/180 (12%)
Query: 32 APWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNT 91
A W L S+ +P+ C R+ +C W+ K Q YT + T
Sbjct: 38 ALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPG-----KETSYTQ--YTVKRT 90
Query: 92 QEWTQEWKECPDYVSAGENSCYFNSSFTSIWIP--YCIKLTSNGGTVDEKC----FSVDE 145
+ ++ C S EN + I IP Y I++ + G K + ++
Sbjct: 91 YAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLEN 150
Query: 146 IVQPDPPIALNWTLLNVS-LTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKW 204
I + +PP + V + GI IQ+ W P A + L+Y L+++ VN T W
Sbjct: 151 IAKTEPP-----KIFRVKPVLGIKRMIQIEWIKPELAPVSSD---LKYTLRFRTVNSTSW 202
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 38.1 bits (87), Expect = 0.025
Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 28/207 (13%)
Query: 49 KEPKFTKCRSPERETFSCHWTD--EVHHGTKNLGPIQLFYTRRNTQEW-TQEWKECPDYV 105
++PK C E + C W E H T +T ++ EW T ++ +C
Sbjct: 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETN--------FTLKS--EWATHKFADCKAKR 176
Query: 106 SAGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEI--VQPDPPIALNWTLLNVS 163
+ S+ + I ++ + G V + D + V+P+PP L+ + +
Sbjct: 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEE 235
Query: 164 LTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT----TSVPVYS 219
L+ I +++ W P + ++L+Y +QY+ + + W + P T +S V
Sbjct: 236 LSSI---LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
Query: 220 LKVDKEYEVRVR-SKQRNSGNYGEFSE 245
LK EY R+R K+ G + ++SE
Sbjct: 289 LKPFTEYVFRIRCMKEDGKGYWSDWSE 315
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 38.1 bits (87), Expect = 0.025
Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 28/207 (13%)
Query: 49 KEPKFTKCRSPERETFSCHWTD--EVHHGTKNLGPIQLFYTRRNTQEW-TQEWKECPDYV 105
++PK C E + C W E H T +T ++ EW T ++ +C
Sbjct: 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETN--------FTLKS--EWATHKFADCKAKR 176
Query: 106 SAGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEI--VQPDPPIALNWTLLNVS 163
+ S+ + I ++ + G V + D + V+P+PP L+ + +
Sbjct: 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEE 235
Query: 164 LTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT----TSVPVYS 219
L+ I +++ W P + ++L+Y +QY+ + + W + P T +S V
Sbjct: 236 LSSI---LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
Query: 220 LKVDKEYEVRVR-SKQRNSGNYGEFSE 245
LK EY R+R K+ G + ++SE
Sbjct: 289 LKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Score = 36.6 bits (83), Expect = 0.073
Identities = 60/238 (25%), Positives = 96/238 (40%), Gaps = 30/238 (12%)
Query: 182 DIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYG 241
D+Q G+ + Y + Y+ + + + T + SL D Y VR+ + G G
Sbjct: 545 DVQNGF-IRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
Query: 242 -EFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFV-FLFSKQQRIKMLILP 299
EF+ T P+ +Q E +++ + F LT +L V F F+K+ IK I P
Sbjct: 604 PEFT----FTTPKFAQGEIEA------IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWP 653
Query: 300 PVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEE 359
VP P I N+ K + +SD ++ + ++I+ D+K
Sbjct: 654 NVPDPSKSHIAQWSPHTPPRHNFNS--------KDQMYSDGNFTDVSVVEIEANDKKPFP 705
Query: 360 SDTDRLLSSDHEK----SHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQ 413
D L EK HS+ G+ G S S P I +D N+ + TS Q
Sbjct: 706 EDLKSLDLFKKEKINTEGHSS-GI--GGSSCMSSSRPSISSSD--ENESSQNTSSTVQ 758
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 37.4 bits (85), Expect = 0.043
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 167 IHAD-IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMM-DPILTTSVPVYSLKVDK 224
I AD + + W+ P + G + Y ++ +E ++T WKM+ + T+ V +L D
Sbjct: 27669 IKADSVILSWDVPED---NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 27725
Query: 225 EYEVRVRSKQR 235
EY+ RVR++ R
Sbjct: 27726 EYQFRVRAENR 27736
Score = 34.7 bits (78), Expect = 0.28
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP-ILTTSVPVYSLKVDKEYEVR 229
I + W P + G + Y ++ KE T W ++ + TS+ + L EY+ R
Sbjct: 25504 ITISWNPP---EYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 25560
Query: 230 VRSKQR-NSGNYGEFSEVL 247
V ++ R +Y E S V+
Sbjct: 25561 VCAENRYGKSSYSESSAVV 25579
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 168 HADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMD--PILTTSVPVYSLKVDKE 225
H + + W P+ G + Y L++KE N WK + PI V L E
Sbjct: 20189 HDSVSLTWTDPKKTG---GSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 20245
Query: 226 YEVRV 230
YE RV
Sbjct: 20246 YEFRV 20250
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 173 VRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPIL--TTSVPVYSLKVDKEYEVRV 230
V W+ P N G V+ Y L+YKE + W + IL T + V L YE RV
Sbjct: 25605 VTWQVPVN---DGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRV 25661
Score = 29.6 bits (65), Expect = 8.9
Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 10/105 (9%)
Query: 136 VDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ 195
VDE PDPP + W + I + W+ P+N G + Y ++
Sbjct: 13575 VDEPVNMSTPATVPDPPENVKWRDRTAN------SIFLTWDPPKN---DGGSRIKGYIVE 13625
Query: 196 YKEVNETKWKMM-DPILTTSVPVYSLKVDKEYEVRVRSKQRNSGN 239
KW +P+ T + V L+ K Y RV++ R +
Sbjct: 13626 RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS 13670
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 37.4 bits (85), Expect = 0.043
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 167 IHAD-IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMM-DPILTTSVPVYSLKVDK 224
I AD + + W+ P + G + Y ++ +E ++T WKM+ + T+ V +L D
Sbjct: 21364 IKADSVILSWDVPED---NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21420
Query: 225 EYEVRVRSKQR 235
EY+ RVR++ R
Sbjct: 21421 EYQFRVRAENR 21431
Score = 34.7 bits (78), Expect = 0.28
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP-ILTTSVPVYSLKVDKEYEVR 229
I + W P + G + Y ++ KE T W ++ + TS+ + L EY+ R
Sbjct: 19199 ITISWNPP---EYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19255
Query: 230 VRSKQR-NSGNYGEFSEVL 247
V ++ R +Y E S V+
Sbjct: 19256 VCAENRYGKSSYSESSAVV 19274
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 168 HADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMD--PILTTSVPVYSLKVDKE 225
H + + W P+ G + Y L++KE N WK + PI V L E
Sbjct: 13884 HDSVSLTWTDPKKTG---GSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 13940
Query: 226 YEVRV 230
YE RV
Sbjct: 13941 YEFRV 13945
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 173 VRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPIL--TTSVPVYSLKVDKEYEVRV 230
V W+ P N G V+ Y L+YKE + W + IL T + V L YE RV
Sbjct: 19300 VTWQVPVN---DGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRV 19356
Score = 29.6 bits (65), Expect = 8.9
Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 10/105 (9%)
Query: 136 VDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ 195
VDE PDPP + W + I + W+ P+N G + Y ++
Sbjct: 7270 VDEPVNMSTPATVPDPPENVKWRDRTAN------SIFLTWDPPKN---DGGSRIKGYIVE 7320
Query: 196 YKEVNETKWKMM-DPILTTSVPVYSLKVDKEYEVRVRSKQRNSGN 239
KW +P+ T + V L+ K Y RV++ R +
Sbjct: 7321 RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS 7365
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 37.4 bits (85), Expect = 0.043
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 167 IHAD-IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMM-DPILTTSVPVYSLKVDK 224
I AD + + W+ P + G + Y ++ +E ++T WKM+ + T+ V +L D
Sbjct: 21297 IKADSVILSWDVPED---NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21353
Query: 225 EYEVRVRSKQR 235
EY+ RVR++ R
Sbjct: 21354 EYQFRVRAENR 21364
Score = 34.7 bits (78), Expect = 0.28
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP-ILTTSVPVYSLKVDKEYEVR 229
I + W P + G + Y ++ KE T W ++ + TS+ + L EY+ R
Sbjct: 19132 ITISWNPP---EYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19188
Query: 230 VRSKQR-NSGNYGEFSEVL 247
V ++ R +Y E S V+
Sbjct: 19189 VCAENRYGKSSYSESSAVV 19207
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 168 HADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMD--PILTTSVPVYSLKVDKE 225
H + + W P+ G + Y L++KE N WK + PI V L E
Sbjct: 13817 HDSVSLTWTDPKKTG---GSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 13873
Query: 226 YEVRV 230
YE RV
Sbjct: 13874 YEFRV 13878
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 173 VRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPIL--TTSVPVYSLKVDKEYEVRV 230
V W+ P N G V+ Y L+YKE + W + IL T + V L YE RV
Sbjct: 19233 VTWQVPVN---DGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRV 19289
Score = 29.6 bits (65), Expect = 8.9
Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 10/105 (9%)
Query: 136 VDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ 195
VDE PDPP + W + I + W+ P+N G + Y ++
Sbjct: 7203 VDEPVNMSTPATVPDPPENVKWRDRTAN------SIFLTWDPPKN---DGGSRIKGYIVE 7253
Query: 196 YKEVNETKWKMM-DPILTTSVPVYSLKVDKEYEVRVRSKQRNSGN 239
KW +P+ T + V L+ K Y RV++ R +
Sbjct: 7254 RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS 7298
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 37.4 bits (85), Expect = 0.043
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 167 IHAD-IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMM-DPILTTSVPVYSLKVDK 224
I AD + + W+ P + G + Y ++ +E ++T WKM+ + T+ V +L D
Sbjct: 21172 IKADSVILSWDVPED---NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21228
Query: 225 EYEVRVRSKQR 235
EY+ RVR++ R
Sbjct: 21229 EYQFRVRAENR 21239
Score = 34.7 bits (78), Expect = 0.28
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP-ILTTSVPVYSLKVDKEYEVR 229
I + W P + G + Y ++ KE T W ++ + TS+ + L EY+ R
Sbjct: 19007 ITISWNPP---EYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19063
Query: 230 VRSKQR-NSGNYGEFSEVL 247
V ++ R +Y E S V+
Sbjct: 19064 VCAENRYGKSSYSESSAVV 19082
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 168 HADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMD--PILTTSVPVYSLKVDKE 225
H + + W P+ G + Y L++KE N WK + PI V L E
Sbjct: 13692 HDSVSLTWTDPKKTG---GSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 13748
Query: 226 YEVRV 230
YE RV
Sbjct: 13749 YEFRV 13753
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 173 VRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPIL--TTSVPVYSLKVDKEYEVRV 230
V W+ P N G V+ Y L+YKE + W + IL T + V L YE RV
Sbjct: 19108 VTWQVPVN---DGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRV 19164
Score = 29.6 bits (65), Expect = 8.9
Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 10/105 (9%)
Query: 136 VDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ 195
VDE PDPP + W + I + W+ P+N G + Y ++
Sbjct: 7078 VDEPVNMSTPATVPDPPENVKWRDRTAN------SIFLTWDPPKN---DGGSRIKGYIVE 7128
Query: 196 YKEVNETKWKMM-DPILTTSVPVYSLKVDKEYEVRVRSKQRNSGN 239
KW +P+ T + V L+ K Y RV++ R +
Sbjct: 7129 RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS 7173
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 37.0 bits (84), Expect = 0.056
Identities = 38/163 (23%), Positives = 61/163 (37%), Gaps = 18/163 (11%)
Query: 56 CRSPERETFSCHWTDEVHHG------TKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGE 109
C++ + E FSC W+ G T L + T W CP G
Sbjct: 120 CQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPW-PCPQ-DPLGA 177
Query: 110 NSCYFNSSFTSIWIPYCIKLTS---NGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTG 166
C + + W Y I +T G + S+ I++PDPP L S+ G
Sbjct: 178 ARCVVHGA--EFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVE----SVPG 231
Query: 167 IHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP 209
++ W P + Q ++ L++ LQY+ W ++P
Sbjct: 232 YPRRLRASWTYPASWPCQPHFL-LKFRLQYRPAQHPAWSTVEP 273
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 37.0 bits (84), Expect = 0.056
Identities = 38/163 (23%), Positives = 61/163 (37%), Gaps = 18/163 (11%)
Query: 56 CRSPERETFSCHWTDEVHHG------TKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGE 109
C++ + E FSC W+ G T L + T W CP G
Sbjct: 120 CQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPW-PCPQ-DPLGA 177
Query: 110 NSCYFNSSFTSIWIPYCIKLTS---NGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTG 166
C + + W Y I +T G + S+ I++PDPP L S+ G
Sbjct: 178 ARCVVHGA--EFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVE----SVPG 231
Query: 167 IHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP 209
++ W P + Q ++ L++ LQY+ W ++P
Sbjct: 232 YPRRLRASWTYPASWPCQPHFL-LKFRLQYRPAQHPAWSTVEP 273
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 37.0 bits (84), Expect = 0.056
Identities = 38/163 (23%), Positives = 61/163 (37%), Gaps = 18/163 (11%)
Query: 56 CRSPERETFSCHWTDEVHHG------TKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGE 109
C++ + E FSC W+ G T L + T W CP G
Sbjct: 120 CQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPW-PCPQ-DPLGA 177
Query: 110 NSCYFNSSFTSIWIPYCIKLTS---NGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTG 166
C + + W Y I +T G + S+ I++PDPP L S+ G
Sbjct: 178 ARCVVHGA--EFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVE----SVPG 231
Query: 167 IHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDP 209
++ W P + Q ++ L++ LQY+ W ++P
Sbjct: 232 YPRRLRASWTYPASWPCQPHFL-LKFRLQYRPAQHPAWSTVEP 273
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 35.0 bits (79), Expect = 0.21
Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 16/129 (12%)
Query: 161 NVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSL 220
+V +T +++ ++W + D Y ++ + +E W M + S Y+L
Sbjct: 1908 DVLVTKSASELTLQWTEGHSGDTP----TTGYVIEARPSDEGLWDMFVKDIPRSATSYTL 1963
Query: 221 KVDK-----EYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGI 275
+DK YE RV + N YGE S Q+ E FY W +++ +
Sbjct: 1964 SLDKLRQGVTYEFRVVAV--NEAGYGEPSNPSTAVSAQV-----EAPFYEEWWFLLVMAL 2016
Query: 276 FGLTVMLFV 284
L V+L V
Sbjct: 2017 SSLIVILLV 2025
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 34.7 bits (78), Expect = 0.28
Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 14/102 (13%)
Query: 302 PVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESD 361
PV ++ IDPD + G+LE T+ A+ DS +F S D V +E D +T+ +
Sbjct: 199 PVASLRAIDPDEGEAGRLE--YTMDALFDSRSNQFFSLDP-VTGAVTTAEELDRETKSTH 255
Query: 362 TDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNAND 403
R+ + DH G R++ IL TD N +D
Sbjct: 256 VFRVTAQDH-----------GMPRRSALATLTILVTDTNDHD 286
>gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
Length = 372
Score = 34.3 bits (77), Expect = 0.36
Identities = 32/148 (21%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 109 ENSCYFNSSFTSIWIPYCIKLT-SNGGTVDEKCFSVDE--IVQPDPPIALNWTLLNVSLT 165
+N C+ I Y + ++ SN + + DE IV+PDPP NV
Sbjct: 161 KNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPE-------NVVAR 213
Query: 166 GIHAD---IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKV 222
+ ++ ++V W+ P + + L++ L+Y+ + +W+ ++ T+ +
Sbjct: 214 PVPSNPRRLEVTWQTPSTWPDPESFP-LKFFLRYRPLILDQWQHVELSDGTAHTITDAYA 272
Query: 223 DKEYEVRVRSKQRNSGNYGEFSEVLYVT 250
KEY ++V +K G + ++S + T
Sbjct: 273 GKEYIIQVAAKDNEIGTWSDWSVAAHAT 300
>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
sapiens]
Length = 372
Score = 34.3 bits (77), Expect = 0.36
Identities = 32/148 (21%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 109 ENSCYFNSSFTSIWIPYCIKLT-SNGGTVDEKCFSVDE--IVQPDPPIALNWTLLNVSLT 165
+N C+ I Y + ++ SN + + DE IV+PDPP NV
Sbjct: 161 KNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPE-------NVVAR 213
Query: 166 GIHAD---IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKV 222
+ ++ ++V W+ P + + L++ L+Y+ + +W+ ++ T+ +
Sbjct: 214 PVPSNPRRLEVTWQTPSTWPDPESFP-LKFFLRYRPLILDQWQHVELSDGTAHTITDAYA 272
Query: 223 DKEYEVRVRSKQRNSGNYGEFSEVLYVT 250
KEY ++V +K G + ++S + T
Sbjct: 273 GKEYIIQVAAKDNEIGTWSDWSVAAHAT 300
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 34.3 bits (77), Expect = 0.36
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Query: 188 MVLEYELQY--KEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSE 245
++LEYE++Y K+ NE ++++ + + L Y VR+ R + YG+FSE
Sbjct: 470 VILEYEVKYYEKDQNERSYRIVRTA-ARNTDIKGLNPLTSYVFHVRA--RTAAGYGDFSE 526
Query: 246 VLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIK 294
L VT + + LL+ + G L V+L ++R K
Sbjct: 527 PLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSK 575
>gi|166362732 ELK1 protein [Homo sapiens]
Length = 428
Score = 33.5 bits (75), Expect = 0.62
Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 8/156 (5%)
Query: 347 ELDIDEPDEKTEESDTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHE 406
E+ ++ P E+ E + +R + K+ + ++G R +++T A
Sbjct: 247 EVKVEGPKEELEVAG-ERGFVPETTKAEPEVPPQEGVPARLPAV---VMDTAGQAGGHAA 302
Query: 407 GTSEVAQPQRLKGEADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAES 466
+ E++QPQ+ + DL + P + P + S +QA P P T
Sbjct: 303 SSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQA----PGPALTPSLLP 358
Query: 467 THQAAHIQLSNPSSLSNIDFYAQVSDITPAGSVVLS 502
TH + L+ S +I F++ +S I P LS
Sbjct: 359 THTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLS 394
>gi|166362730 ELK1 protein [Homo sapiens]
Length = 428
Score = 33.5 bits (75), Expect = 0.62
Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 8/156 (5%)
Query: 347 ELDIDEPDEKTEESDTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHE 406
E+ ++ P E+ E + +R + K+ + ++G R +++T A
Sbjct: 247 EVKVEGPKEELEVAG-ERGFVPETTKAEPEVPPQEGVPARLPAV---VMDTAGQAGGHAA 302
Query: 407 GTSEVAQPQRLKGEADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAES 466
+ E++QPQ+ + DL + P + P + S +QA P P T
Sbjct: 303 SSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQA----PGPALTPSLLP 358
Query: 467 THQAAHIQLSNPSSLSNIDFYAQVSDITPAGSVVLS 502
TH + L+ S +I F++ +S I P LS
Sbjct: 359 THTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLS 394
>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
sapiens]
Length = 371
Score = 33.1 bits (74), Expect = 0.80
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 16/144 (11%)
Query: 190 LEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYE--VRVRSKQRNSGNYGEFSEVL 247
L YE+QY+ +T+W+ T +V + L +K Y VRV++ + G S+
Sbjct: 146 LLYEVQYRSPFDTEWQSKQEN-TCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWS 204
Query: 248 YVTLPQMSQF--TCEEDFYFP------WLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILP 299
VT Q + C E P ++LI I + +L + L+ K R+K ++P
Sbjct: 205 EVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLW-KLWRVKKFLIP 263
Query: 300 PVPVPKIKGIDPDL--LKEGKLEE 321
VP P K I P L + +G +E
Sbjct: 264 SVPDP--KSIFPGLFEIHQGNFQE 285
>gi|102469034 janus kinase 1 [Homo sapiens]
Length = 1154
Score = 32.7 bits (73), Expect = 1.1
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 445 QPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSSLSNIDFYAQVSDITPAGSVVLSPG 504
+P+V+ EK K + L + E+ H+ + +N ++ +++ I SVV
Sbjct: 328 KPNVVSVEKEKNK-LKRKKLENKHKKDEEKNKIREEWNNFSYFPEITHIVIKESVVSINK 386
Query: 505 QKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADAKK--CIPVAPHIKVES 554
Q NK + H E +S L+D + ADA C VAP + V +
Sbjct: 387 QDNKKMELKLSSHEEALSFVS---LVDGYFRLTADAHHYLCTDVAPPLIVHN 435
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 7/85 (8%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT--TSVPVYSLKVDKEYEV 228
+Q+ W+ P A+ + ++ +Y L Y+++N M I+ T++ + LK D Y+V
Sbjct: 935 VQLSWQPPVLAE--RNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDV 992
Query: 229 RVRSKQRNSGNYGEFS-EVLYVTLP 252
+VR+ S G +S V + TLP
Sbjct: 993 KVRA--HTSKGPGPYSPSVQFRTLP 1015
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 7/85 (8%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT--TSVPVYSLKVDKEYEV 228
+Q+ W+ P A+ + ++ +Y L Y+++N M I+ T++ + LK D Y+V
Sbjct: 922 VQLSWQPPVLAE--RNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDV 979
Query: 229 RVRSKQRNSGNYGEFS-EVLYVTLP 252
+VR+ S G +S V + TLP
Sbjct: 980 KVRA--HTSKGPGPYSPSVQFRTLP 1002
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 7/85 (8%)
Query: 171 IQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT--TSVPVYSLKVDKEYEV 228
+Q+ W+ P A+ + ++ +Y L Y+++N M I+ T++ + LK D Y+V
Sbjct: 926 VQLSWQPPVLAE--RNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDV 983
Query: 229 RVRSKQRNSGNYGEFS-EVLYVTLP 252
+VR+ S G +S V + TLP
Sbjct: 984 KVRA--HTSKGPGPYSPSVQFRTLP 1006
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,868,272
Number of Sequences: 37866
Number of extensions: 1319165
Number of successful extensions: 3939
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 3825
Number of HSP's gapped (non-prelim): 177
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.