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Search of human proteins with 4503537
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503537 eukaryotic translation initiation factor 4E binding
protein 3 [Homo sapiens]
(100 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503537 eukaryotic translation initiation factor 4E binding p... 214 2e-56
gi|4758260 eukaryotic translation initiation factor 4E binding p... 113 4e-26
gi|4758258 eukaryotic translation initiation factor 4E binding p... 101 1e-22
gi|224465238 hypothetical protein LOC283999 [Homo sapiens] 30 0.31
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 30 0.41
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 30 0.41
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 30 0.41
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 30 0.41
gi|94536830 DMRT-like family C2 [Homo sapiens] 30 0.54
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 29 0.70
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 29 0.70
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 29 0.70
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 29 0.70
gi|7657307 LIM domains containing 1 [Homo sapiens] 29 0.92
gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo... 29 0.92
gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbe... 29 0.92
gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalp... 29 0.92
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 28 1.2
gi|210032580 SET domain containing 1B [Homo sapiens] 28 1.2
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 28 1.6
gi|151301215 widely-interspaced zinc finger motifs [Homo sapiens] 28 2.0
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 27 2.7
gi|24041029 nitric oxide synthase 2A [Homo sapiens] 27 3.5
gi|31542265 tribbles 3 [Homo sapiens] 27 3.5
gi|149944516 tet oncogene family member 3 [Homo sapiens] 27 3.5
gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosi... 27 3.5
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 27 3.5
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 27 3.5
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 27 3.5
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 27 3.5
>gi|4503537 eukaryotic translation initiation factor 4E binding
protein 3 [Homo sapiens]
Length = 100
Score = 214 bits (544), Expect = 2e-56
Identities = 100/100 (100%), Positives = 100/100 (100%)
Query: 1 MSTSTSCPIPGGRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCC 60
MSTSTSCPIPGGRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCC
Sbjct: 1 MSTSTSCPIPGGRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCC 60
Query: 61 LPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQFEMDI 100
LPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQFEMDI
Sbjct: 61 LPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQFEMDI 100
>gi|4758260 eukaryotic translation initiation factor 4E binding
protein 2 [Homo sapiens]
Length = 120
Score = 113 bits (282), Expect = 4e-26
Identities = 55/92 (59%), Positives = 67/92 (72%), Gaps = 6/92 (6%)
Query: 15 QLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTPPT-- 72
QLP Y TTPGGTL++TTPGGTRIIYDRKFLL+ +NSP+A+TPPC LP IPGVT+P T
Sbjct: 29 QLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQTPPCHLPNIPGVTSPGTLI 88
Query: 73 ----APLSKLEELKEQETEEEIPDDAQFEMDI 100
++ L L + + + DDAQFEMDI
Sbjct: 89 EDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI 120
>gi|4758258 eukaryotic translation initiation factor 4E binding
protein 1 [Homo sapiens]
Length = 118
Score = 101 bits (252), Expect = 1e-22
Identities = 50/88 (56%), Positives = 62/88 (70%), Gaps = 4/88 (4%)
Query: 17 PDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTP----PT 72
P YSTTPGGTL++TTPGGTRIIYDRKFL+EC+NSP+ +TPP LP IPGVT+P P
Sbjct: 31 PGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVTKTPPRDLPTIPGVTSPSSDEPP 90
Query: 73 APLSKLEELKEQETEEEIPDDAQFEMDI 100
S+ E + +++QFEMDI
Sbjct: 91 MEASQSHLRNSPEDKRAGGEESQFEMDI 118
>gi|224465238 hypothetical protein LOC283999 [Homo sapiens]
Length = 394
Score = 30.4 bits (67), Expect = 0.31
Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 14/80 (17%)
Query: 4 STSCPIPGGRDQLPDCYSTTPGGTLYATTPGGTR--------IIYDRKFLLECKNSPIAR 55
STS P P GR Q P GG TPGG R + R + P+ R
Sbjct: 104 STSSPFPQGRAQRPQ-----RGGVDLPATPGGPRGQCAGRSGDVLRRAGRRRARPPPVPR 158
Query: 56 TPPCCLPQIP-GVTTPPTAP 74
P P+ P G TP +P
Sbjct: 159 LPAPRAPRRPRGPATPDPSP 178
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 30.0 bits (66), Expect = 0.41
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 61 LPQIPGVTTPPTAPLSKLEELKEQETEEE 89
LP P VTTPP A S E+ + +E EE+
Sbjct: 689 LPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 717
>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
sapiens]
Length = 1336
Score = 30.0 bits (66), Expect = 0.41
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 61 LPQIPGVTTPPTAPLSKLEELKEQETEEE 89
LP P VTTPP A S E+ + +E EE+
Sbjct: 274 LPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 30.0 bits (66), Expect = 0.41
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 61 LPQIPGVTTPPTAPLSKLEELKEQETEEE 89
LP P VTTPP A S E+ + +E EE+
Sbjct: 454 LPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 30.0 bits (66), Expect = 0.41
Identities = 20/75 (26%), Positives = 28/75 (37%), Gaps = 14/75 (18%)
Query: 16 LPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTPPTAPL 75
L C +TTPG L+ P SP + P +P TPPT
Sbjct: 357 LLSCPTTTPGLPLFTPAPSTA--------------SPTTQPPTLSIPNPSRSYTPPTPTT 402
Query: 76 SKLEELKEQETEEEI 90
SKL + + + E +
Sbjct: 403 SKLPTIPDWDGRERV 417
>gi|94536830 DMRT-like family C2 [Homo sapiens]
Length = 367
Score = 29.6 bits (65), Expect = 0.54
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 4 STSCPIPGGRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQ 63
+T +P G++ + T G L A TP G + SP++ TP P
Sbjct: 117 TTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPW 176
Query: 64 IPGVTTPP--TAPLSKLEELKEQETEEEIPDDAQFE 97
+PG PP + P + L QE +P F+
Sbjct: 177 VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFD 212
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 29.3 bits (64), Expect = 0.70
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 30 ATTPGGTRIIYDRKFLLECKNSPIARTPPCCL---PQIPGVTTPPTAPLSKLEELKEQET 86
A P R + +R + + +NSP+A++ P P IP + P PLS+ ++
Sbjct: 514 ADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVE 573
Query: 87 EEEIP 91
+E P
Sbjct: 574 PQEGP 578
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 29.3 bits (64), Expect = 0.70
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 30 ATTPGGTRIIYDRKFLLECKNSPIARTPPCCL---PQIPGVTTPPTAPLSKLEELKEQET 86
A P R + +R + + +NSP+A++ P P IP + P PLS+ ++
Sbjct: 514 ADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVE 573
Query: 87 EEEIP 91
+E P
Sbjct: 574 PQEGP 578
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 29.3 bits (64), Expect = 0.70
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 30 ATTPGGTRIIYDRKFLLECKNSPIARTPPCCL---PQIPGVTTPPTAPLSKLEELKEQET 86
A P R + +R + + +NSP+A++ P P IP + P PLS+ ++
Sbjct: 514 ADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVE 573
Query: 87 EEEIP 91
+E P
Sbjct: 574 PQEGP 578
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 29.3 bits (64), Expect = 0.70
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 30 ATTPGGTRIIYDRKFLLECKNSPIARTPPCCL---PQIPGVTTPPTAPLSKLEELKEQET 86
A P R + +R + + +NSP+A++ P P IP + P PLS+ ++
Sbjct: 514 ADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVE 573
Query: 87 EEEIP 91
+E P
Sbjct: 574 PQEGP 578
>gi|7657307 LIM domains containing 1 [Homo sapiens]
Length = 676
Score = 28.9 bits (63), Expect = 0.92
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Query: 45 LLECKNSPIARTPPCCLPQIPGVTTPPTAPLSKLEELKEQETEE 88
LL+ +SP R P C P +PG P+A KLE L ++ E
Sbjct: 418 LLDSPSSPRVRLP--CQPLVPGPELRPSAAELKLEALTQRLERE 459
>gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo
sapiens]
Length = 292
Score = 28.9 bits (63), Expect = 0.92
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 66 GVTTPPTAPLSK-LEELKEQETEEEIPDDAQFEMD 99
GV PP P+ + EE KE E E+E DD+ E D
Sbjct: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKD 47
>gi|17402871 BRCA2 and CDKN1A-interacting protein isoform
BCCIPbeta [Homo sapiens]
Length = 314
Score = 28.9 bits (63), Expect = 0.92
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 66 GVTTPPTAPLSK-LEELKEQETEEEIPDDAQFEMD 99
GV PP P+ + EE KE E E+E DD+ E D
Sbjct: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKD 47
>gi|7706581 BRCA2 and CDKN1A-interacting protein isoform
BCCIPalpha [Homo sapiens]
Length = 322
Score = 28.9 bits (63), Expect = 0.92
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 66 GVTTPPTAPLSK-LEELKEQETEEEIPDDAQFEMD 99
GV PP P+ + EE KE E E+E DD+ E D
Sbjct: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKD 47
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 28.5 bits (62), Expect = 1.2
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 57 PPCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQ 95
PP P PG+T AP + +E+ K+ E E+E P Q
Sbjct: 1035 PPASPPPTPGITRKEEAPENVVEK-KDLELEKEAPSPFQ 1072
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 28.5 bits (62), Expect = 1.2
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 42 RKFLLECKNSPIARTPPCCLPQIPGVTTPPTAPLSKL--EELKEQETEEEIP 91
R L+ +N+ I PP PQ P PP +KL +EL Q E IP
Sbjct: 1525 RTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIP 1576
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/28 (42%), Positives = 16/28 (57%)
Query: 54 ARTPPCCLPQIPGVTTPPTAPLSKLEEL 81
ARTP C +PG PP + L L++L
Sbjct: 293 ARTPACPTRDLPGPQAPPPSGLQGLDDL 320
>gi|151301215 widely-interspaced zinc finger motifs [Homo sapiens]
Length = 794
Score = 27.7 bits (60), Expect = 2.0
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 5/73 (6%)
Query: 24 PGGTLYATTPGGTRIIYDRKFLLECKNSPI-----ARTPPCCLPQIPGVTTPPTAPLSKL 78
PG +L A +P I K L SP+ A PP PG+ P K
Sbjct: 262 PGSSLEARSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFPGLAAPSLPKKLKP 321
Query: 79 EELKEQETEEEIP 91
E+++ + E +P
Sbjct: 322 EQIRVEIKREMLP 334
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 27.3 bits (59), Expect = 2.7
Identities = 11/31 (35%), Positives = 17/31 (54%)
Query: 56 TPPCCLPQIPGVTTPPTAPLSKLEELKEQET 86
+P C PQ G +PP + + LK++ET
Sbjct: 248 SPECASPQFEGPLSPPPINYNGIFSLKQEET 278
>gi|24041029 nitric oxide synthase 2A [Homo sapiens]
Length = 1153
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 6/38 (15%)
Query: 55 RTPPCCLPQ----IPGVTTPPTAPLSKLEELKEQETEE 88
R PPC L Q +TTPPT L L++L + TEE
Sbjct: 818 RLPPCSLSQALTYFLDITTPPTQLL--LQKLAQVATEE 853
>gi|31542265 tribbles 3 [Homo sapiens]
Length = 358
Score = 26.9 bits (58), Expect = 3.5
Identities = 13/34 (38%), Positives = 17/34 (50%), Gaps = 5/34 (14%)
Query: 41 DRKFLLECKNSPIARTPPCCLPQIPGVTTPPTAP 74
+R ++ P R PPC LP +PPTAP
Sbjct: 28 ERPVQKRARSGPQPRLPPCLLP-----LSPPTAP 56
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 26.9 bits (58), Expect = 3.5
Identities = 10/33 (30%), Positives = 20/33 (60%)
Query: 62 PQIPGVTTPPTAPLSKLEELKEQETEEEIPDDA 94
P PG PP++P+ +L + +E ++++P A
Sbjct: 419 PSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPA 451
>gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 1 [Homo sapiens]
Length = 775
Score = 26.9 bits (58), Expect = 3.5
Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 58 PCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQFEM 98
P P+ P + T P+ L L + Q +EE+ +D FE+
Sbjct: 131 PIAAPE-PELKTDPSLDLHSLSSAETQPAQEELREDPDFEI 170
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 46 LECKNSPIAR--TPPCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQ 95
+EC+ P + PP PQ P VT P A S+ E E E P +A+
Sbjct: 183 MECRGGPQPQHSQPP---PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAE 231
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 46 LECKNSPIAR--TPPCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQ 95
+EC+ P + PP PQ P VT P A S+ E E E P +A+
Sbjct: 183 MECRGGPQPQHSQPP---PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAE 231
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 46 LECKNSPIAR--TPPCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQ 95
+EC+ P + PP PQ P VT P A S+ E E E P +A+
Sbjct: 183 MECRGGPQPQHSQPP---PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAE 231
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 51 SPIARTPPCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQFE 97
SP+ PPC P IPG P P K E +K E E ++ FE
Sbjct: 513 SPVG-PPPCPSPTIPG---PLPTPSRKQEIIKTTEQLIEAVNNGDFE 555
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,709,746
Number of Sequences: 37866
Number of extensions: 321322
Number of successful extensions: 1256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 1193
Number of HSP's gapped (non-prelim): 118
length of query: 100
length of database: 18,247,518
effective HSP length: 71
effective length of query: 29
effective length of database: 15,559,032
effective search space: 451211928
effective search space used: 451211928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.