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Search of human proteins with 4503351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b
[Homo sapiens]
(1616 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 3312 0.0
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 3298 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 80 2e-14
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 74 1e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 74 1e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 73 2e-12
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 72 3e-12
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 72 4e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 71 7e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 71 1e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 70 1e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 69 3e-11
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 68 8e-11
gi|148746195 trichohyalin [Homo sapiens] 67 1e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 67 1e-10
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 66 2e-10
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 65 4e-10
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 65 4e-10
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 65 4e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 65 4e-10
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 65 5e-10
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 65 5e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 65 7e-10
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 64 9e-10
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 64 2e-09
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 64 2e-09
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 64 2e-09
gi|157266334 tubby like protein 1 [Homo sapiens] 64 2e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 63 3e-09
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 62 3e-09
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 3312 bits (8587), Expect = 0.0
Identities = 1616/1616 (100%), Positives = 1616/1616 (100%)
Query: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
Sbjct: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
Query: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV
Sbjct: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
Query: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP 180
GMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP
Sbjct: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP 180
Query: 181 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK 240
QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK
Sbjct: 181 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK 240
Query: 241 EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE 300
EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE
Sbjct: 241 EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE 300
Query: 301 EKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYL 360
EKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYL
Sbjct: 301 EKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYL 360
Query: 361 DDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLC 420
DDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLC
Sbjct: 361 DDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLC 420
Query: 421 PIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFS 480
PIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFS
Sbjct: 421 PIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFS 480
Query: 481 TSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGL 540
TSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGL
Sbjct: 481 TSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGL 540
Query: 541 NLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQAR 600
NLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQAR
Sbjct: 541 NLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQAR 600
Query: 601 RQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQ 660
RQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQ
Sbjct: 601 RQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQ 660
Query: 661 QPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQ 720
QPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQ
Sbjct: 661 QPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQ 720
Query: 721 GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVT 780
GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVT
Sbjct: 721 GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVT 780
Query: 781 ALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPS 840
ALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPS
Sbjct: 781 ALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPS 840
Query: 841 ENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLA 900
ENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLA
Sbjct: 841 ENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLA 900
Query: 901 EMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPR 960
EMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPR
Sbjct: 901 EMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPR 960
Query: 961 KEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNK 1020
KEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNK
Sbjct: 961 KEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNK 1020
Query: 1021 FYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGP 1080
FYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGP
Sbjct: 1021 FYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGP 1080
Query: 1081 NRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLR 1140
NRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLR
Sbjct: 1081 NRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLR 1140
Query: 1141 TLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMA 1200
TLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMA
Sbjct: 1141 TLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMA 1200
Query: 1201 GETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRP 1260
GETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRP
Sbjct: 1201 GETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRP 1260
Query: 1261 RFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAP 1320
RFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAP
Sbjct: 1261 RFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAP 1320
Query: 1321 GEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNG 1380
GEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNG
Sbjct: 1321 GEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNG 1380
Query: 1381 ASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLP 1440
ASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLP
Sbjct: 1381 ASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLP 1440
Query: 1441 NIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCL 1500
NIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCL
Sbjct: 1441 NIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCL 1500
Query: 1501 PHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFP 1560
PHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFP
Sbjct: 1501 PHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFP 1560
Query: 1561 DTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIKEEEAAKD 1616
DTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIKEEEAAKD
Sbjct: 1561 DTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIKEEEAAKD 1616
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 3298 bits (8552), Expect = 0.0
Identities = 1615/1632 (98%), Positives = 1615/1632 (98%), Gaps = 16/1632 (0%)
Query: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
Sbjct: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
Query: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV
Sbjct: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
Query: 121 GMADANSPPKPLSKPRTPRRSKSDGEAK----------------PEPSPSPRITRKSTRQ 164
GMADANSPPKPLSKPRTPRRSKSDGEAK EPSPSPRITRKSTRQ
Sbjct: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ 180
Query: 165 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 224
TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER
Sbjct: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 240
Query: 225 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 284
AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK
Sbjct: 241 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300
Query: 285 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 344
KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM
Sbjct: 301 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 360
Query: 345 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ 404
NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ
Sbjct: 361 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ 420
Query: 405 HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW 464
HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW
Sbjct: 421 HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW 480
Query: 465 WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY 524
WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY
Sbjct: 481 WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY 540
Query: 525 EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL 584
EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL
Sbjct: 541 EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL 600
Query: 585 IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK 644
IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK
Sbjct: 601 IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK 660
Query: 645 ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE 704
ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE
Sbjct: 661 ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE 720
Query: 705 VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS 764
VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS
Sbjct: 721 VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS 780
Query: 765 VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ 824
VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ
Sbjct: 781 VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ 840
Query: 825 LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP 884
LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP
Sbjct: 841 LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP 900
Query: 885 TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE 944
TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE
Sbjct: 901 TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE 960
Query: 945 AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK 1004
AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK
Sbjct: 961 AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK 1020
Query: 1005 SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY 1064
SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY
Sbjct: 1021 SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY 1080
Query: 1065 GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA 1124
GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA
Sbjct: 1081 GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA 1140
Query: 1125 CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS 1184
CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS
Sbjct: 1141 CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS 1200
Query: 1185 TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK 1244
TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK
Sbjct: 1201 TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK 1260
Query: 1245 NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY 1304
NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY
Sbjct: 1261 NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY 1320
Query: 1305 GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT 1364
GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT
Sbjct: 1321 GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT 1380
Query: 1365 ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR 1424
ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR
Sbjct: 1381 ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR 1440
Query: 1425 MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA 1484
MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA
Sbjct: 1441 MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA 1500
Query: 1485 CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ 1544
CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ
Sbjct: 1501 CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ 1560
Query: 1545 HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA 1604
HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA
Sbjct: 1561 HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA 1620
Query: 1605 SAKIKEEEAAKD 1616
SAKIKEEEAAKD
Sbjct: 1621 SAKIKEEEAAKD 1632
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 80.1 bits (196), Expect = 2e-14
Identities = 82/330 (24%), Positives = 141/330 (42%), Gaps = 20/330 (6%)
Query: 27 RLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE--LSEEGYLAKVKS 84
++K E+ + EK KE + + + +T++ ++ + E K KEE EEG +
Sbjct: 437 KVKSEEKIKVVEKS-EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE 495
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARS--EARRVGMADANSPPKPLSKPRTPRRSK 142
++ A + E + +A+S EA+ +A SP + S + +K
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555
Query: 143 SDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAK---RKPQEESERAKSDESIKEEDKD 199
+ ++ PE + KS + + AK PAK + P E K+ +KEE K
Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 200 QDEKRRRVTSRERVARPLPAEEPERAKSGTRTE----KEEERDEKEEKRLRSQTKEPTPK 255
E + V +E P + PE+AKS T+ E ++ + EKEE + + K P
Sbjct: 615 PAEAKSPV--KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 256 Q-KLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDE 314
+ K E+ +A ++ E K+E K P+ + + E K PEK + +E
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK---SPEKAKSPVKEEAKSPEKAKSPVKEE 729
Query: 315 KDEDEKEEKRRKTTPKEPTE-KKMARAKTV 343
EK + K K P + K +AKT+
Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Score = 77.0 bits (188), Expect = 1e-13
Identities = 77/301 (25%), Positives = 119/301 (39%), Gaps = 32/301 (10%)
Query: 65 ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD 124
ET + +E+ E +V K+ E G E G E E + +
Sbjct: 453 ETVIVEEQTEETQVTEEVTEEEEKEAKEEEG----KEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKP---EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQ 181
A SP K P +KS EAK E + SP + + + AK P + K
Sbjct: 509 AASPEKEAKSP-VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567
Query: 182 EESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK----EEER 237
E+ E AKS +K +K + ++E P A+ PE+AKS + E E +
Sbjct: 568 EKEE-AKSPAEVKSPEKAKSP------AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS 620
Query: 238 DEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRS-------QP 290
KEE + ++ K P +K K EA++ +A E + K +K +S P
Sbjct: 621 PVKEEAKSPAEVKSP---EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677
Query: 291 KDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK---MARAKTVMNSK 347
+ + + E K PEK + +E EK + K K P + K AKT +K
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK 737
Query: 348 T 348
+
Sbjct: 738 S 738
Score = 71.6 bits (174), Expect = 6e-12
Identities = 63/228 (27%), Positives = 105/228 (46%), Gaps = 24/228 (10%)
Query: 124 DANSPPKPLS----KPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRK 179
+A SP K S + ++P ++KS +A+ + SP + ++ + AK P K +
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK---SPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 180 PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
+ E+AKS +KEE K ++ + V +E P A+ PE+AK+ E +
Sbjct: 716 AKSP-EKAKSP--VKEEAKTPEKAKSPV--KEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD---------EKKHRSQP 290
KEE R + K +KEE +A ED EK+ K +P
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830
Query: 291 KDLAAKRRPEEKEPEK--VNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+++ K P++ E EK P+ ++EK + +KEE +K PK E+K
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPK-TEEKKDSKKEEAPKKEAPKPKVEEK 877
Score = 68.9 bits (167), Expect = 4e-11
Identities = 64/262 (24%), Positives = 110/262 (41%), Gaps = 26/262 (9%)
Query: 131 PLSKPRTPRRSKSDGEAKPEPSPSP--RITRKSTRQTTITSHFAKGPAKRKPQEESERAK 188
P +K ++S + PE + SP + + + AK P K P++E ++
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS- 822
Query: 189 SDESIKEEDKDQDEKRR---RVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRL 245
+KEE+K Q+ K + + E+ EE + +K +KE + + EEK+
Sbjct: 823 ---PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879
Query: 246 RSQTKEPTPKQKLKEE----------PDREARAGVQADEDEDGDEKDEKKHRSQPKDLAA 295
+ K K + K+E P++EA A V+ ED EK E + +P D A
Sbjct: 880 PAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA-KKEPDDAKA 938
Query: 296 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQ 355
K + E ++ P+ +D KEEK +K K TE K ++ + PK +
Sbjct: 939 KEPSKPAEKKEAAPE-----KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA-E 992
Query: 356 CGQYLDDPDLKYGQHPPDAVDE 377
+ D K + P A ++
Sbjct: 993 KAEKSSSTDQKDSKPPEKATED 1014
Score = 65.5 bits (158), Expect = 4e-10
Identities = 73/259 (28%), Positives = 112/259 (43%), Gaps = 32/259 (12%)
Query: 102 EVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKP---EPSPSPRIT 158
EV + + A+ EA+ A+A SP K +K +KS EAK E + SP
Sbjct: 577 EVKSPEKAKSPAKEEAK--SPAEAKSPEK--AKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 159 RKSTRQTTITSHFAKGPAKRKPQEESERAKSDES----IKEEDKDQDEKRRRVT----SR 210
+ + + T AK P K K E+ E AKS E +K E K ++ + V S
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEE-AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP 691
Query: 211 ERVARPLP--AEEPERAKSGTRTE-KEEERDE---KEEKRLRSQTKEPTPKQKLKEEPDR 264
E+ P+ A+ PE+AKS + E K E+ + KEE + + K P +
Sbjct: 692 EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE--------- 742
Query: 265 EARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 324
EA++ +A E D K ++ R P +K PEK + +E EK +
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP 802
Query: 325 RKTTPKEPTEKKMARAKTV 343
K K P EK++ + + V
Sbjct: 803 LKEDAKAP-EKEIPKKEEV 820
Score = 65.1 bits (157), Expect = 5e-10
Identities = 62/250 (24%), Positives = 107/250 (42%), Gaps = 18/250 (7%)
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHF 171
+A+S A A SP K +K +P +KS +AK SP + +
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAK--SPAEAKSPEKAK---SPVKEEAKSPAEAKSPVKEE 625
Query: 172 AKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE--EPERAKSGT 229
AK PA+ K E+++ +E+ K +K + ++ S E+ P+ AE PE+AKS
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEA-KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Query: 230 RTEKEEERDEKEEKRLRSQTKEPTP-KQKLKEEPDREARAGVQADEDEDGDEKDEKKHRS 288
+ E + EK + ++ + K P K +KEE +A E+ EK + +
Sbjct: 685 KAEAKSP--EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Query: 289 QPKDLAAKRRPEE------KEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 342
+ K + PE+ K PE P + + +K ++ K+ KE K +AK+
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV-KSPEKAKS 801
Query: 343 VMNSKTHPPK 352
+ P+
Sbjct: 802 PLKEDAKAPE 811
Score = 62.0 bits (149), Expect = 4e-09
Identities = 100/436 (22%), Positives = 155/436 (35%), Gaps = 101/436 (23%)
Query: 6 APARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLE 65
+PA+ + P+ + +K+ + K VKE+ E E E
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Query: 66 TKLRKEELSEEGYLAKVKSLLNKDLSLE-NGAHAYNREVNGRLENGNQARSEARRVGMA- 123
K ++ S E AK + E V ++ +A+S + +
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 124 ---------DANSPPKPLS----KPRTPRRSKSD--GEAK-PEPSPSPRITR----KSTR 163
+A SP K S + +TP ++KS EAK PE + SP + KS
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765
Query: 164 QTTITSHFAKGPAKRKPQEES----ERAKSDESIKEEDK-DQDEKRRRVTSRERVARPLP 218
T A+ PA + P++ E KS E K K D + + +E V P+
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 219 AEE-PERAKSGTRTEKEEER--------DEKEEKRLRSQTKEPTPKQKLKEE-------- 261
EE P+ K +K EE +EK++ + K+ PK K++E+
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 262 --------------------PDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEE 301
P++EA A V+ ED EK E + +P D AK +
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA-KKEPDDAKAKEPSKP 944
Query: 302 KEPEKVNPQISDEKDEDEK--EEKRR---------KTTPKEP------------------ 332
E ++ P+ D K+E K EEK + KT KEP
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Query: 333 -------TEKKMARAK 341
TE K A+ K
Sbjct: 1005 SKPPEKATEDKAAKGK 1020
Score = 59.3 bits (142), Expect = 3e-08
Identities = 70/326 (21%), Positives = 126/326 (38%), Gaps = 56/326 (17%)
Query: 33 RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSL 92
+DSL + + +L H+ + + L+ +LR + L + + LLN ++L
Sbjct: 339 KDSLERQ---RSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMAL 395
Query: 93 ENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPR-TPRRSKSDGEAKPEP 151
+ AY + + G E R+G P P S P P+ K +
Sbjct: 396 DIEIAAYRKLLEG----------EECRIGFG-----PIPFSLPEGLPKIPSVSTHIKVKS 440
Query: 152 SPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRE 211
++ KS ++T I +E++E + E + EE++ + ++
Sbjct: 441 EEKIKVVEKSEKETVIV------------EEQTEETQVTEEVTEEEEKEAKE-------- 480
Query: 212 RVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ 271
EE + + G E+EE +EE + + +P+++ K EA++ +
Sbjct: 481 --------EEGKEEEGG---EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 272 ADEDEDGDEKDEKKHRS-----QPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 326
A E + K + +S P AK PE K PEK + E EK + K
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 327 TTPKEPTE-KKMARAKTVMNSKTHPP 351
K P E K +AK+ + + P
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSP 615
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 73.9 bits (180), Expect = 1e-12
Identities = 61/271 (22%), Positives = 117/271 (43%), Gaps = 30/271 (11%)
Query: 96 AHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSP 155
+H+ + + + + RS +R+ + SP K SK R R+S+S ++ +
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK----- 376
Query: 156 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 215
RK TR+ K ++ ++E ER K E KE K++D + R RE+
Sbjct: 377 ---RKDTREKIKEKERVK---EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430
Query: 216 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADED 275
E E+ R +++E+ +KE++R + ++KE K+K K++ R A
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK-KDKKSRTPPRSYNASRR 489
Query: 276 EDGDEKDEKKHRSQPKDLAAK-----------------RRPEEKEPEKVNPQISDEKDED 318
++ ++ RS+ + + R ++K+ EK IS E+ E
Sbjct: 490 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS-ERRER 548
Query: 319 EKEEKRRKTTPKEPTEKKMARAKTVMNSKTH 349
E+ RK++ ++K+ + T + K H
Sbjct: 549 ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 579
Score = 66.2 bits (160), Expect = 2e-10
Identities = 55/223 (24%), Positives = 101/223 (45%), Gaps = 25/223 (11%)
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEES 184
A P S R RS+S +K S RK ++ + + +++K + S
Sbjct: 292 AIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 351
Query: 185 E-----RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
+ R+KS E K + +R+ +RE++ +E ER K R ++ E E
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRK-DTREKI------KEKERVKEKDREKEREREKE 404
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
+E+++ R + K+ + + E DRE D+++D + + EK+H K +
Sbjct: 405 REKEKERGKNKD----RDKEREKDRE------KDKEKDREREREKEHEKDRDKEKEKEQD 454
Query: 300 EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 342
+EKE EK S E DE K++K+ +T P+ + +R+ +
Sbjct: 455 KEKEREK---DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Score = 63.5 bits (153), Expect = 2e-09
Identities = 49/226 (21%), Positives = 97/226 (42%), Gaps = 8/226 (3%)
Query: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP 180
G ++ + S R+ RS S ++ + S S +R R + + + K
Sbjct: 298 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 357
Query: 181 QEES-ERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
+ +S ER KS DK +D R ++ +ERV +E ER K EKE+ER +
Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREKEREREKE---REKEKERGK 413
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
+++ + K+K +E + + E E +K++++ + + K++ KR+
Sbjct: 414 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 300 EEKE---PEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 342
++K P N E+ +R +++ + P K + K+
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 519
Score = 50.1 bits (118), Expect = 2e-05
Identities = 51/224 (22%), Positives = 90/224 (40%), Gaps = 18/224 (8%)
Query: 120 VGMADANSPPKPLS------KPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAK 173
V AD NS P+ L+ R + + S+ P +P+ K + + +
Sbjct: 227 VEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEE--VMKRVRE 284
Query: 174 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 233
+ E E KS+E + + R +S+ R +R++S R+
Sbjct: 285 AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRR-------KRSQSKHRSRS 337
Query: 234 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDL 293
+++ R RS K P K+ E + D+ +D EK ++K R + KD
Sbjct: 338 HNRSRSRQKDRRRS--KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 395
Query: 294 AAKR-RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+R R +E+E EK + D E EK+ ++ K +E +K
Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Score = 42.4 bits (98), Expect = 0.004
Identities = 49/221 (22%), Positives = 97/221 (43%), Gaps = 9/221 (4%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R + KD E++ EKE KEK ++ E + + K R+ E +E + K
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSD 144
+ + ++E++ + + ++R+ R +A+ + S+ R RRS+S
Sbjct: 449 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY---NASRRSRSSSRERRRRRSRSS 505
Query: 145 GEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEE-SERAKSDE--SIKEEDKDQD 201
+ P S I RKS+R + S K + K ++ SER + + S+++ D+D
Sbjct: 506 SRS---PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 562
Query: 202 EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEE 242
K + + + +EP+ + S +K+ R E+ +
Sbjct: 563 GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 41.2 bits (95), Expect = 0.008
Identities = 45/199 (22%), Positives = 70/199 (35%), Gaps = 26/199 (13%)
Query: 130 KPLSKPRTPRRSKS---DGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 186
K K R R K D + + E R+ R I K R P
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486
Query: 187 AKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR 246
++ S E + +R R +SR + R+ S K++++ EKE
Sbjct: 487 SRRSRSSSRERR---RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE----- 538
Query: 247 SQTKEPTPKQKLKEEPDREARAGV-QADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPE 305
+ + E +RE + ++ D DG EK EK S K + KEP+
Sbjct: 539 --------RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTS------LKEKEHNKEPD 584
Query: 306 KVNPQISDEKDEDEKEEKR 324
+ D+KD EE +
Sbjct: 585 SSVSKEVDDKDAPRTEENK 603
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 73.9 bits (180), Expect = 1e-12
Identities = 61/271 (22%), Positives = 117/271 (43%), Gaps = 30/271 (11%)
Query: 96 AHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSP 155
+H+ + + + + RS +R+ + SP K SK R R+S+S ++ +
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK----- 260
Query: 156 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 215
RK TR+ K ++ ++E ER K E KE K++D + R RE+
Sbjct: 261 ---RKDTREKIKEKERVK---EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314
Query: 216 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADED 275
E E+ R +++E+ +KE++R + ++KE K+K K++ R A
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK-KDKKSRTPPRSYNASRR 373
Query: 276 EDGDEKDEKKHRSQPKDLAAK-----------------RRPEEKEPEKVNPQISDEKDED 318
++ ++ RS+ + + R ++K+ EK IS E+ E
Sbjct: 374 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS-ERRER 432
Query: 319 EKEEKRRKTTPKEPTEKKMARAKTVMNSKTH 349
E+ RK++ ++K+ + T + K H
Sbjct: 433 ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 463
Score = 66.2 bits (160), Expect = 2e-10
Identities = 55/223 (24%), Positives = 101/223 (45%), Gaps = 25/223 (11%)
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEES 184
A P S R RS+S +K S RK ++ + + +++K + S
Sbjct: 176 AIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 235
Query: 185 E-----RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
+ R+KS E K + +R+ +RE++ +E ER K R ++ E E
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRK-DTREKI------KEKERVKEKDREKEREREKE 288
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
+E+++ R + K+ + + E DRE D+++D + + EK+H K +
Sbjct: 289 REKEKERGKNKD----RDKEREKDRE------KDKEKDREREREKEHEKDRDKEKEKEQD 338
Query: 300 EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 342
+EKE EK S E DE K++K+ +T P+ + +R+ +
Sbjct: 339 KEKEREK---DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Score = 63.5 bits (153), Expect = 2e-09
Identities = 49/226 (21%), Positives = 97/226 (42%), Gaps = 8/226 (3%)
Query: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP 180
G ++ + S R+ RS S ++ + S S +R R + + + K
Sbjct: 182 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 241
Query: 181 QEES-ERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
+ +S ER KS DK +D R ++ +ERV +E ER K EKE+ER +
Sbjct: 242 RSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREKEREREKE---REKEKERGK 297
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
+++ + K+K +E + + E E +K++++ + + K++ KR+
Sbjct: 298 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 300 EEKE---PEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 342
++K P N E+ +R +++ + P K + K+
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 403
Score = 50.1 bits (118), Expect = 2e-05
Identities = 51/224 (22%), Positives = 90/224 (40%), Gaps = 18/224 (8%)
Query: 120 VGMADANSPPKPLS------KPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAK 173
V AD NS P+ L+ R + + S+ P +P+ K + + +
Sbjct: 111 VEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEE--VMKRVRE 168
Query: 174 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 233
+ E E KS+E + + R +S+ R +R++S R+
Sbjct: 169 AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRR-------KRSQSKHRSRS 221
Query: 234 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDL 293
+++ R RS K P K+ E + D+ +D EK ++K R + KD
Sbjct: 222 HNRSRSRQKDRRRS--KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 279
Query: 294 AAKR-RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+R R +E+E EK + D E EK+ ++ K +E +K
Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Score = 42.4 bits (98), Expect = 0.004
Identities = 49/221 (22%), Positives = 97/221 (43%), Gaps = 9/221 (4%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R + KD E++ EKE KEK ++ E + + K R+ E +E + K
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSD 144
+ + ++E++ + + ++R+ R +A+ + S+ R RRS+S
Sbjct: 333 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY---NASRRSRSSSRERRRRRSRSS 389
Query: 145 GEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEE-SERAKSDE--SIKEEDKDQD 201
+ P S I RKS+R + S K + K ++ SER + + S+++ D+D
Sbjct: 390 SRS---PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 446
Query: 202 EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEE 242
K + + + +EP+ + S +K+ R E+ +
Sbjct: 447 GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 41.2 bits (95), Expect = 0.008
Identities = 45/199 (22%), Positives = 70/199 (35%), Gaps = 26/199 (13%)
Query: 130 KPLSKPRTPRRSKS---DGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 186
K K R R K D + + E R+ R I K R P
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370
Query: 187 AKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR 246
++ S E + +R R +SR + R+ S K++++ EKE
Sbjct: 371 SRRSRSSSRERR---RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE----- 422
Query: 247 SQTKEPTPKQKLKEEPDREARAGV-QADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPE 305
+ + E +RE + ++ D DG EK EK S K + KEP+
Sbjct: 423 --------RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTS------LKEKEHNKEPD 468
Query: 306 KVNPQISDEKDEDEKEEKR 324
+ D+KD EE +
Sbjct: 469 SSVSKEVDDKDAPRTEENK 487
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 73.2 bits (178), Expect = 2e-12
Identities = 76/328 (23%), Positives = 142/328 (43%), Gaps = 21/328 (6%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQL-CDLETKLRKEELSEEGYLAKVK 83
R R D ERD EKE ++K +TE + + D +T ++E + + +
Sbjct: 105 RERQTDRERDRQREKERNRQK----ERERETEREGERGRDRQTDGQRERERQRDAEKERE 160
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
+++ + NR+ E Q R E R + + + + R R +
Sbjct: 161 RQTDRERQRQT---ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER- 216
Query: 144 DGEAKPEPSPSPRITRKSTRQ-TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD- 201
E + E + R+ RQ T + +R + E+ER K E ++ D+D+D
Sbjct: 217 --ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 202 --EKRRRVTSRERVARPLPAEEPERAKSGTR-TEKEEERDEKEEK-RLRSQTKEPTPKQK 257
++R R T R+R R E ER + R E+E ER+ K E+ R R + +E + +
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
Query: 258 LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 317
E +RE + Q + D + + + ++ R Q + + R +++ + + ++D
Sbjct: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
Query: 318 DEKEEKRRKTTP----KEPTEKKMARAK 341
D ++E+ R+T + TEK+ R K
Sbjct: 395 DRQKERERQTEKDRDGQRETEKQREREK 422
Score = 68.6 bits (166), Expect = 5e-11
Identities = 73/359 (20%), Positives = 155/359 (43%), Gaps = 40/359 (11%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R R D ER TE+ KE+ + + + + + E + KE +E+ + + +
Sbjct: 159 RERQTDRERQRQTERNRQKERE-------REKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD---ANSPPKPLSKPRTPRRS 141
++ E + R E Q ++E R A+ A+ K R R
Sbjct: 212 ---RERERETETETERKRQTDR-ERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 142 KSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD 201
+ + + + RK R+T + +R+ + E ER ++ + +E +++++
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTE-RDRETERKRERQRERERERERNRKRERERERERE 326
Query: 202 EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD-----------EKEEKRLRSQTK 250
+R+R T R+R E+ K +TE + ER+ E+E +R R + +
Sbjct: 327 RERQRETERDR-------EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR 379
Query: 251 EPTPKQKLKE---EPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR---RPEEKEP 304
+ +++ +E + DR+ Q ++D DG +++ +K R + KD ++R R E+E
Sbjct: 380 QSAREREERERDRDRDRQKERERQTEKDRDG-QRETEKQREREKDRESERGRERGREREK 438
Query: 305 EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDP 363
+K + + + + + +R+++T + AR+ V + P + I+ +DP
Sbjct: 439 QKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDP 497
Score = 62.4 bits (150), Expect = 3e-09
Identities = 57/241 (23%), Positives = 109/241 (45%), Gaps = 23/241 (9%)
Query: 106 RLENGNQARSEARRVGMA----DANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKS 161
R G+Q R +G A D + + K R RR K E + + RK
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD--------RKR 79
Query: 162 TRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEE 221
R+ H K R+ Q + E+ + ++ +E D+ ++++R R RER
Sbjct: 80 ERRREKDRH-RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG 138
Query: 222 PERAKSGTRTEKEEERD-EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDE 280
+R G R E+E +RD EKE +R + ++ ++ ++E +RE E + +
Sbjct: 139 RDRQTDGQR-ERERQRDAEKERERQTDRERQRQTERNRQKEREREK----NRQERRERER 193
Query: 281 KDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARA 340
+ EK+++++ + R E+E E+ ++ K + ++E R++ T +E EK+ R
Sbjct: 194 QREKENKTEDRH---SERGRERERERETETETERKRQTDRERDRQRKTERE-REKQAERE 249
Query: 341 K 341
+
Sbjct: 250 R 250
Score = 59.3 bits (142), Expect = 3e-08
Identities = 52/207 (25%), Positives = 96/207 (46%), Gaps = 18/207 (8%)
Query: 143 SDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDE 202
+DG+ + R R+ RQT + KR+ + E +R + + +E +D+++
Sbjct: 49 ADGDDRERNRQKERERRREKRQTE-----RETDRKRERRREKDRHRKRDRHRERQRDREK 103
Query: 203 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP 262
+R R T RER + E ER + R E+E ER+ + R + ++ +++ + +
Sbjct: 104 ERERQTDRERDRQ----REKERNRQKER-ERETEREGE-----RGRDRQTDGQRERERQR 153
Query: 263 DREARAGVQAD-EDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE 321
D E Q D E + E++ +K R + K+ +RR E++ EK N + D E +E
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKN-RQERRERERQREKEN-KTEDRHSERGRE 211
Query: 322 EKRRKTTPKEPTEKKMARAKTVMNSKT 348
+R + T E K+ + KT
Sbjct: 212 RERERETETETERKRQTDRERDRQRKT 238
Score = 47.4 bits (111), Expect = 1e-04
Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 12/172 (6%)
Query: 176 AKRKPQEESERAKSDESIKEEDKDQDEK-RRRVTSRERVARPLPAEEPERAKSGTRTEKE 234
++R+P + + +D D D++ R R RER E K R EK+
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 235 --------EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEK--DEK 284
ER EK QT +Q+ KE ++ R E E G ++ D +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 285 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+ R + +D A K R + + E+ + + E E+E+ R++ +E +K
Sbjct: 147 RERERQRD-AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Score = 39.3 bits (90), Expect = 0.031
Identities = 35/154 (22%), Positives = 68/154 (44%), Gaps = 14/154 (9%)
Query: 201 DEKRRRVTSRERVARPLPAEEPERAKSGTRT-----EKEEERD----EKEEKRLRSQTKE 251
D RRR S+E R + + A R E+E R+ E+E R R + +E
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 252 PTPKQK----LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKV 307
+K + + DRE Q D + D +++++++R + ++ +R E +
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERD-RQREKERNRQKERERETEREGERGRDRQT 143
Query: 308 NPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341
+ Q E+ D ++E+ R+T + + + R K
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 72.4 bits (176), Expect = 3e-12
Identities = 65/276 (23%), Positives = 120/276 (43%), Gaps = 64/276 (23%)
Query: 138 PRRSKSDGEAKPEP---------SPSPRIT---RKSTRQTTITSHFAKGPAKRKPQEESE 185
PR+ K DG+ E S SPR + R+S R++ SH +G E E
Sbjct: 237 PRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELE 296
Query: 186 RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRT-------------- 231
R K + ++ E K+++++RRR S +R + ER +S +R+
Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER 356
Query: 232 EKEEERD---------------EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDE 276
EKE ER EKE +R R ++KE + +++E+ +E + + +D+
Sbjct: 357 EKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDK 416
Query: 277 DGDEKD---------EKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK------- 320
+K+ E+KHRS+ + A +R + EK + ++ K++ K
Sbjct: 417 RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQ 476
Query: 321 -------EEKRRKTTPKEPTEKKMARAKTVMNSKTH 349
+ K+R+ +P + +K +R+K + + H
Sbjct: 477 GRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH 512
Score = 71.6 bits (174), Expect = 6e-12
Identities = 63/264 (23%), Positives = 120/264 (45%), Gaps = 16/264 (6%)
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
S +++L E RE R + ++RS R + + S + S+ R+ R
Sbjct: 289 SSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348
Query: 144 ----DGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKD 199
D E + E R R ++ + ++ + +E+ R + +E +EDKD
Sbjct: 349 RRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 200 QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQK-- 257
++R R R+ ++ R++S R + R KR RS++KE + K K
Sbjct: 409 --DRRHRDDKRDSKKE----KKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNE 462
Query: 258 LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 317
KE+ ++ +R+G Q D EK +K+ S K+ + KR ++ K + SD KD+
Sbjct: 463 SKEKSNKRSRSGSQGRTDSV--EKSKKREHSPSKEKSRKRSRSKERSHKRDH--SDSKDQ 518
Query: 318 DEKEEKRRKTTPKEPTEKKMARAK 341
+K ++RR + ++ +++K + K
Sbjct: 519 SDKHDRRRSQSIEQESQEKQHKNK 542
Score = 50.8 bits (120), Expect = 1e-05
Identities = 40/196 (20%), Positives = 84/196 (42%), Gaps = 15/196 (7%)
Query: 162 TRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEE 221
TR I +G + E R++S + R R RE E
Sbjct: 235 TRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRE 294
Query: 222 PERAKSGTRTEKEEERDEKEEKRLRS-----QTKEPTPKQKLKEEPDREARAGVQADEDE 276
ER K R E+E + EKE +R RS + + +++ + R G + D D
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR 354
Query: 277 DGDEKDEK---------KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT 327
+ ++++E+ K R ++ +R E + ++ ++ ++K +++K+++R +
Sbjct: 355 EREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD 414
Query: 328 TPKE-PTEKKMARAKT 342
++ EKK +R+++
Sbjct: 415 DKRDSKKEKKHSRSRS 430
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 72.0 bits (175), Expect = 4e-12
Identities = 46/200 (23%), Positives = 95/200 (47%), Gaps = 16/200 (8%)
Query: 132 LSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE 191
+SKP T R S+ E + ++ R+ +G ++K +++ ER K E
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRE--------RGKKEKKKRKKRERGKERE 76
Query: 192 SIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKE 251
++E + Q ++RR R+R E +R + + +KE + E+E K+ R + ++
Sbjct: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
Query: 252 PTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 311
K+K ++E RE G + E+ KK + + ++ +R +E++ E+ +
Sbjct: 137 KRRKKKRRKERKREKERGKR--------ERKRKKRKKEEREKKRERNRKERKKERERKER 188
Query: 312 SDEKDEDEKEEKRRKTTPKE 331
+ K E +KE +++K K+
Sbjct: 189 RERKKERKKERRKKKERKKD 208
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/190 (22%), Positives = 89/190 (46%), Gaps = 6/190 (3%)
Query: 164 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 223
Q SH +K +R+ + + ER + ++ +E +K++ +R + ++R R E
Sbjct: 18 QMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR-----ERG 72
Query: 224 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDE 283
+ + R E+E++R E+ EK R + KE +++ + + + + + + ++ E
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 284 KKHRSQPKDLAAKRRPEEKEPEK-VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 342
+K + + K K R EKE K + +K+E EK+ +R + K+ E+K R +
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Query: 343 VMNSKTHPPK 352
K K
Sbjct: 193 KERKKERRKK 202
Score = 59.3 bits (142), Expect = 3e-08
Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 19/218 (8%)
Query: 127 SPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAK-RKPQEESE 185
S K + R R+ + + E K E + RK + K K RK + E E
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
Query: 186 RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRL 245
R K + K+ ++ Q +R R +ER +E ER R K ++R +K+ ++
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKER-------KERERENKQRRERKRKKRRKKKRRKE 146
Query: 246 RSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPE 305
R + KE +++ +++ +E R ++K E+ + + K+ K R E K+
Sbjct: 147 RKREKERGKRERKRKKRKKEER-----------EKKRERNRKERKKERERKERRERKKER 195
Query: 306 KVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTV 343
K + E+ +D K +++ + P + TV
Sbjct: 196 KKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTV 233
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/210 (19%), Positives = 86/210 (40%), Gaps = 14/210 (6%)
Query: 86 LNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDG 145
LN +L + + +H E + R +R + + K + R+ + G
Sbjct: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
Query: 146 EAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRR 205
+ + RK R+ K ++K +E +R + + K+E K+++ + +
Sbjct: 73 KERERKRKEREKQRKERRE----KERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
Query: 206 RVTSRERVARPLPAEEPERAKSGTRTEKE--------EERDEKEEKRLRSQTKEPTPKQK 257
+ R+R R ER + R ++E EER++K E+ + + KE K++
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
Query: 258 --LKEEPDREARAGVQADEDEDGDEKDEKK 285
K+E +E R + +D D + + +
Sbjct: 189 RERKKERKKERRKKKERKKDRKTDRQTDSQ 218
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 71.2 bits (173), Expect = 7e-12
Identities = 47/186 (25%), Positives = 90/186 (48%), Gaps = 9/186 (4%)
Query: 164 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 223
Q SH +K + Q E + + ++E K + E R+ RER R E+
Sbjct: 18 QMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKER 77
Query: 224 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTP-------KQKLKEEPDREARAGVQADEDE 276
+ + G + +K E + E+ E++ R + KE K+K K+E R ++ G + + E
Sbjct: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 277 DGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE-DEKEEKRRKTTPKEPTEK 335
+ +++E+K R + K+ K R ++ ++ Q+ ++++E EKE K RK + E+
Sbjct: 138 ER-KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 336 KMARAK 341
K R +
Sbjct: 197 KKERER 202
Score = 70.5 bits (171), Expect = 1e-11
Identities = 44/173 (25%), Positives = 87/173 (50%), Gaps = 10/173 (5%)
Query: 179 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE----KE 234
K + ESER K ++ ++++++R+R ++ EE ER K E +E
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 235 EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLA 294
+E+ +K+EK+ R +T + +++ KEE RE R + ++E E++ K+ + + +
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 295 AKRRPEEKEPEKVNPQISD------EKDEDEKEEKRRKTTPKEPTEKKMARAK 341
++ E KE E+ + + +K+ + KE + RK K+ E+K R K
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Score = 69.7 bits (169), Expect = 2e-11
Identities = 62/227 (27%), Positives = 100/227 (44%), Gaps = 26/227 (11%)
Query: 101 REVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRK 160
RE+ R E G + R R+ + + K R R K E K E R +K
Sbjct: 43 REIETRKE-GKKERESERKKERREREKRKREREKERKRERGKK--EKKGERKKEERERKK 99
Query: 161 STRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 220
R+ K KRK +E+ ER ++ + KE ++ ++ KR RER
Sbjct: 100 RRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERER-------- 149
Query: 221 EPERAKSGTRTEKEEERDEKE-EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGD 279
+ E+E+ER+ KE +KR R Q E ++K KE +R+ R + + E
Sbjct: 150 --------KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR---ERNRKERKK 198
Query: 280 EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 326
E++ K+ R + K+ K+ +KE +K EK+ ++E K RK
Sbjct: 199 ERERKERRERKKE-RKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 67.4 bits (163), Expect = 1e-10
Identities = 48/214 (22%), Positives = 104/214 (48%), Gaps = 11/214 (5%)
Query: 122 MADANSPPKPLSKPRTP---RRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKR 178
M + KP ++P R + + E + E RK R+ K +R
Sbjct: 19 MVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRER-----EKRKRER 73
Query: 179 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKE-EER 237
+ + + ER K ++ + + ++++ K+RR + + + K RT KE +ER
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 238 DEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR 297
+ KEE++ R + KE ++K + E +RE + + + + G++++E+K + + + +R
Sbjct: 134 ERKEERK-REERKE-RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Query: 298 RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 331
+E++ E+ + + K E +K+E+R+K K+
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 57.0 bits (136), Expect = 1e-07
Identities = 50/238 (21%), Positives = 101/238 (42%), Gaps = 29/238 (12%)
Query: 54 QTEIKNQLCDLETKL--RKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGN 111
Q+EI+ + ++ET+ +KE SE + + ++ E RE + + G
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKER-----KRERGKKEKKGE 89
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHF 171
+ + E R K R + +GE K + + R T +
Sbjct: 90 RKKEERER--------------KKRRREKENKEGEEKEKRKKKEKKERGRTSK------- 128
Query: 172 AKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRT 231
+G + + +E + + K+E+++++ +R+ RER EE + + R
Sbjct: 129 -EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 232 EKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 289
++E R E++++R R + +E ++K KEE +E + Q + E K E+K R +
Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 36.6 bits (83), Expect = 0.20
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 18/120 (15%)
Query: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 292
+ E R+ + E R + K+ ++ KE +RE R + EK+ K+ R + K+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKRER--------EKERKRERGK-KE 85
Query: 293 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 352
+R+ EE+E +K EKE K + K ++K R +T K K
Sbjct: 86 KKGERKKEERERKK---------RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERK 136
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 70.9 bits (172), Expect = 1e-11
Identities = 47/197 (23%), Positives = 94/197 (47%), Gaps = 20/197 (10%)
Query: 172 AKGPAKRKPQEESERAKSDESIKEEDKDQ-DEKRRRVTSRERVARPLPAEEPERAKSGTR 230
A GP +K ++++ + S++S +EE++ Q ++ +RV P P + +A +
Sbjct: 70 ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLP-PGKAAAKASESSS 128
Query: 231 TEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP 290
+E+ + D++E+++ + K P+ K + P ++A++ +D D D +DE +P
Sbjct: 129 SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKS---SDSDSDSSSEDEPPKNQKP 185
Query: 291 KDLAAKRRPEEKEPEK---VNPQISDEK------------DEDEKEEKRRKTTPKEPTEK 335
K + + K P K P+I++ K D+ EE++ TPK+ K
Sbjct: 186 KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 336 KMARAKTVMNSKTHPPK 352
K AK + + T P +
Sbjct: 246 KQVVAKAPVKAATTPTR 262
Score = 60.8 bits (146), Expect = 1e-08
Identities = 66/317 (20%), Positives = 121/317 (38%), Gaps = 56/317 (17%)
Query: 67 KLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADAN 126
K+ + +L G +AK K+ S + EV G +A A+RVG+
Sbjct: 62 KVPERKLQANGPVAK-KAKKKASSSDSEDSSEEEEEVQG--PPAKKAAVPAKRVGLPPGK 118
Query: 127 SPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 186
+ K + S D E + P + + + A + P ++++
Sbjct: 119 AAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAK------------AAKAPPKKAKS 166
Query: 187 AKSDESIKEEDKDQDEKRRRVT----SRERVARPLPAEEPER------AKSGTRTEKEEE 236
+ SD ED+ ++ ++T + A P PA + A S + +
Sbjct: 167 SDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226
Query: 237 RDEKEEKRLRSQTKEPTPKQ--------KLKEEPDREARAGVQADEDEDGDEKDEKKHRS 288
D+ EE++ + K+ PK+ K P R++ + + DE+ ++K K++
Sbjct: 227 SDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286
Query: 289 QP-------------KDLAA---KRRPEEKEPEKVNPQISDEKDEDEKEEKR-------R 325
P K L K+ E+++P + + SDE D +EEK+
Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVS 346
Query: 326 KTTPKEPTEKKMARAKT 342
K T K P KK A + +
Sbjct: 347 KATTKPPPAKKAAESSS 363
Score = 57.4 bits (137), Expect = 1e-07
Identities = 59/289 (20%), Positives = 106/289 (36%), Gaps = 37/289 (12%)
Query: 131 PLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSD 190
P++K + S SD E E + ++ + + P + + SE + S+
Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEE--VQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSE 130
Query: 191 ESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKR------ 244
ES ++D ++D+K++ V + P++AKS DE + +
Sbjct: 131 ES-SDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITP 189
Query: 245 --LRSQTKEPTPKQKL--KEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE 300
+++QTK P + K + A + + D+ +E+K + PK K++
Sbjct: 190 VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVV 249
Query: 301 EKEPEKV------NPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCI 354
K P K S++ DE+EE+ K+P + K +V PPK
Sbjct: 250 AKAPVKAATTPTRKSSSSEDSSSDEEEEQ------KKPMKNKPGPYSSVPPPSAPPPK-- 301
Query: 355 QCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALP 403
G PP E Q D ++S E + P
Sbjct: 302 ----------KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPP 340
Score = 55.5 bits (132), Expect = 4e-07
Identities = 64/318 (20%), Positives = 124/318 (38%), Gaps = 37/318 (11%)
Query: 70 KEELSEEGYLAKVKSLLNKDLSLENG-AHAYNREVNGRLENGNQARSEARRVGMADANSP 128
+EE +G AK ++ K + L G A A E + E+ + E ++
Sbjct: 92 EEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVK 151
Query: 129 PKPLSKPRTPRRSKSD-------GEAKPEPSPSPRITRKSTRQTT--------ITSHFAK 173
P+ + P+++KS E +P + P+IT + + T A
Sbjct: 152 PQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIAN 211
Query: 174 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR-PLPAEEPERAKSGTRTE 232
G A S + SD+S EE+K ++ V ++ VA+ P+ A KS + +
Sbjct: 212 GKAASSSSSSSSSSSSDDS--EEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSED 269
Query: 233 KEEERDEKEEKRLRSQT---------KEPTPKQKLKEEPDREA---RAGVQADEDED--- 277
+ +E+++K ++++ P PK+ L +P ++A + V++ ED
Sbjct: 270 SSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDES 329
Query: 278 ---GDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 334
+E+ + ++ K P +K E + + ED++ + T K +
Sbjct: 330 DSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSN 389
Query: 335 KKMARAKTVMNSKTHPPK 352
K K+ PK
Sbjct: 390 KPAVTTKSPAVKPAAAPK 407
Score = 50.1 bits (118), Expect = 2e-05
Identities = 54/277 (19%), Positives = 110/277 (39%), Gaps = 32/277 (11%)
Query: 122 MADANSPPKPLSKPRTPRRSKSDGEAKPE---PSPSPRITRKSTRQTTITSHFAKGPAKR 178
++ A + P P K SD ++ + PS T+ S+ + +T+
Sbjct: 345 VSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAA 404
Query: 179 KPQEE--------SERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPAEEPER 224
P++ + +A S S +E ++EK +++ + + A LPA++
Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQ--- 461
Query: 225 AKSGTRTEKEE----ERDEKEEKRLRSQTKEPTPKQKLKEEPDR-------EARAGVQAD 273
A G+R + +E+EEK +S K+ K P + +A + +
Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSS 521
Query: 274 EDEDGDEKDEK-KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEP 332
D+ +E++EK K + P+ A K + + ++E+E+++K K
Sbjct: 522 SDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSG 581
Query: 333 TEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQ 369
+ KK + + ++T K I+ P K G+
Sbjct: 582 SLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGE 618
Score = 48.9 bits (115), Expect = 4e-05
Identities = 52/219 (23%), Positives = 85/219 (38%), Gaps = 18/219 (8%)
Query: 130 KPLSKPRTP--------RRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKG----PAK 177
KP + P+ P R ++ E S S K TT AK PAK
Sbjct: 401 KPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK 460
Query: 178 RKPQEESERAK-SDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSG----TRTE 232
+ PQ + + SD S EE++++ K ++VA +P AK G + +
Sbjct: 461 QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSS 520
Query: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 292
++ E+EE++L+ + K A+ G A E+ +E+ +K K
Sbjct: 521 SSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKS 580
Query: 293 LAAKRRPE-EKEPEKVNPQISDEKDEDEKEEKRRKTTPK 330
+ K+R + E E PQ K + +RK K
Sbjct: 581 GSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEK 619
Score = 34.3 bits (77), Expect = 1.0
Identities = 34/147 (23%), Positives = 60/147 (40%), Gaps = 19/147 (12%)
Query: 122 MADANSPPKPLS----KPRTPRRSKSDGEAKPEP-------SPSPRITRKSTRQTTITSH 170
+A +P KP S K + S SD ++ E SP P+ K+ + +T+
Sbjct: 497 VAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAP-KANGTSALTAQ 555
Query: 171 FAKGPAKRKPQEESERAKS------DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 224
K AK +EE E+ K+ S+K+ +++ K +++ P P+R
Sbjct: 556 NGKA-AKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKR 614
Query: 225 AKSGTRTEKEEERDEKEEKRLRSQTKE 251
K R R +EE + S+ +
Sbjct: 615 KKGEKRASSPFRRVREEEIEVDSRVAD 641
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 70.5 bits (171), Expect = 1e-11
Identities = 89/371 (23%), Positives = 160/371 (43%), Gaps = 47/371 (12%)
Query: 11 PTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEI------KNQLCDL 64
PT+ ++SLP RR D + TEKE E +E +TE KN D
Sbjct: 123 PTITDASLSLPS--RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180
Query: 65 ETKLRKEELSEEGYLAKVK---------SLLNKDLSLENGAHAYNREV-NGRLENGNQAR 114
E ++++ EE K K ++ ++ + E+ + NG++ + +
Sbjct: 181 EENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQ 240
Query: 115 SEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKG 174
E R G + + K + + R++++ A+ E RI K+ + I A+
Sbjct: 241 EEEREQGSDEISHHEKMEEEDK--ERAEAE-RARLEAEERERI--KAEQDKKIADERARI 295
Query: 175 PAKRKP---QEESERAKSDESIKEEDKDQDEKRRRVTSRERVA----RPLPAEEPERAKS 227
A+ K + E A+ E ++EE+K E+R+R+ E+ A + + EE A+
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355
Query: 228 GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREAR---------AGVQADEDEDG 278
R ++EE+R +E +R R++ +E ++ K E + G + ++ +G
Sbjct: 356 RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEG 415
Query: 279 DEKDEKKHRSQPKDLAA-KRRPEEK------EPEKVNPQISDEKDEDEKEEKRRK-TTPK 330
+EKK + A K++ EEK + EK+ K E+ K+EK +K PK
Sbjct: 416 KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK 475
Query: 331 EPTEKKMARAK 341
E + M R K
Sbjct: 476 EEVKSFMDRKK 486
Score = 63.5 bits (153), Expect = 2e-09
Identities = 75/342 (21%), Positives = 136/342 (39%), Gaps = 44/342 (12%)
Query: 54 QTEIKNQLCDLETKLRKEELSEEGYLAKVK-------SLLNKDLSLENGAHAYNREVNGR 106
Q E ++ LE R+EE ++ ++ ++ + LSL + + N
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 107 LENGNQARSEARRVGMADANSPPKPLSKPR---TPRRSKSDGEAKPEPSPSPRI------ 157
E ++ S R + + + K K K D E + E P+
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 158 ---------TRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESI------KEEDKDQDE 202
T +S +T + S + +P++E ER + + I +EEDK++ E
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Query: 203 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE--------RDEKEEKRLRSQTKEPT- 253
R E R ++ + A R E EE+ R+ +E +R+R + K
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Query: 254 PKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR---RPEEKEPEKVNPQ 310
+Q++KEE R A + E+E ++ ++ + + K A +R R EE+E KV Q
Sbjct: 327 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 311 ISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 352
+++ E++K + E E+K+ K V K K
Sbjct: 387 KRNKQLEEKKHAMQETKIKGEKVEQKI-EGKWVNEKKAQEDK 427
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/199 (21%), Positives = 86/199 (43%), Gaps = 21/199 (10%)
Query: 181 QEESERAKSDESIKEE--DKDQDEKRRRVTSRERV--ARPLPAEEPERAKSGTRTEKEEE 236
+EE+ R + + +E K ++E +VT + V +P EE + + T+ E ++E
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 93
Query: 237 ---------RDEKEEKRL-----RSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD 282
R+E+ +KRL R + +PT P R + +E + +EK
Sbjct: 94 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153
Query: 283 E---KKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 339
E +++ + + K + + + D++ E+E+EEK ++ + E + M
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE 213
Query: 340 AKTVMNSKTHPPKCIQCGQ 358
KT + + ++ GQ
Sbjct: 214 EKTTESQEETVVMSLKNGQ 232
Score = 42.7 bits (99), Expect = 0.003
Identities = 48/259 (18%), Positives = 109/259 (42%), Gaps = 33/259 (12%)
Query: 157 ITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARP 216
+ R+ TIT P++R +++ A+++ + KEE + ++R + E V +
Sbjct: 115 LERQKEFDPTITDASLSLPSRRM---QNDTAENETTEKEEKSESRQERYEIEETETVTKS 171
Query: 217 LPAEEPERAKSGTRTEKEEERDEKEEKRLRS---------------QTKEPTPKQKLK-- 259
+ A+ + +KE+E +E+E+ + S +++E T LK
Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNG 231
Query: 260 ----EEPDREARAGVQADE---DEDGDEKDEKKHRSQPKDLAAKRRPEEK--EPEKVNPQ 310
EEP +E +DE E +E+D+++ ++ L A+ R K + +K+ +
Sbjct: 232 QISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Query: 311 IS----DEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLK 366
+ +EK ++ E+R + E++ A+ K + + Q + + + +
Sbjct: 292 RARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Query: 367 YGQHPPDAVDEPQMLTNEK 385
+ +E + E+
Sbjct: 352 AAEERQRIKEEEKRAAEER 370
Score = 41.6 bits (96), Expect = 0.006
Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 11/149 (7%)
Query: 199 DQDEKRRRVTSRERVARPLPAE----------EPERAKSGTRTEKEEERDEKEEKRLRSQ 248
D E+RR + ++R L AE E E A+ R ++E +K+E+ Q
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 249 TKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEK-V 307
+ PD EA+ + E DE + ++ ++ KR E E +K
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 308 NPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+P I+D + T E TEK+
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKE 150
Score = 39.3 bits (90), Expect = 0.031
Identities = 72/351 (20%), Positives = 139/351 (39%), Gaps = 51/351 (14%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R+R+K+ E+ + E++ +KE+ E Q + + E + R +EE AKV+
Sbjct: 328 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR--AEEEEKAKVEE 385
Query: 85 LLNKDLSLENGAHAYN----------REVNGRLENGNQARSEARRVGMADANSPPKPLS- 133
++ LE HA +++ G+ N +A+ + + + K
Sbjct: 386 Q-KRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444
Query: 134 ----------KPRTPRRSKSDGEAKPEPSPSPRITRKSTRQ---TTITSHFAKGPAKRKP 180
KP + D + K + P + R+ T + S + +
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 181 QEESERAK-----SDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEE 235
E+ ++ S ++ + E Q E +R+ R +EE E+ K + E
Sbjct: 505 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALE 564
Query: 236 ERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAA 295
+ K+++ R + E +++ +EE DR+ R E++EK+ + K+
Sbjct: 565 LEELKKKREERRKVLEEEEQRRKQEEADRKLR------------EEEEKR---RLKEEIE 609
Query: 296 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNS 346
+RR E E + P+ D +D+K K TPK + K RA+ + S
Sbjct: 610 RRRAEAAEKRQKMPE--DGLSDDKKPFK--CFTPKGSSLKIEERAEFLNKS 656
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 69.3 bits (168), Expect = 3e-11
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 34/154 (22%)
Query: 177 KRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE 236
K+K +E E +++E+ +EE+K+ K +R R+ E E+ K TEK +E
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK---------EKEKKKKTKETEKRKE 54
Query: 237 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK 296
++E+E+KR R + K+ KEE +RE + +E+E+ ++++E+K + + K
Sbjct: 55 KEEEEKKRKRKRKKK-------KEEEERE-----EEEEEEEEEKEEEEKEEGRRRKKKKK 102
Query: 297 RRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPK 330
RR +E+E EK K+++RRKT K
Sbjct: 103 RRRKEEEEEK-------------KKKRRRKTKKK 123
Score = 60.8 bits (146), Expect = 1e-08
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 24/130 (18%)
Query: 220 EEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGD 279
+E E + TE+EEE++ K +++ + + KE K+K KE R+ +
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK------------ 55
Query: 280 EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEE-------KRRKTTPKEP 332
E++EKK + + K++ EE+E E+ + +EK+E+EKEE K+R+ +E
Sbjct: 56 EEEEKKRKRK-----RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Query: 333 TEKKMARAKT 342
+KK R KT
Sbjct: 111 EKKKKRRRKT 120
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/95 (29%), Positives = 55/95 (57%), Gaps = 6/95 (6%)
Query: 173 KGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 232
K K K +E+ ++ K+ E+ K ++K+++EK+R+ +++ EE ER + E
Sbjct: 30 KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK------KEEEEREEEEEEEE 83
Query: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREAR 267
+E+E +EKEE R R + K+ K++ +E+ + R
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Score = 45.1 bits (105), Expect = 6e-04
Identities = 22/102 (21%), Positives = 59/102 (57%), Gaps = 3/102 (2%)
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
K++K+ + +T+E ++ +EE ++E G + ++ ++ ++ EKK +++ + ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKE---GKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57
Query: 300 EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341
EEK+ ++ + +E++ +E+EE+ + +E E+ R K
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Score = 43.5 bits (101), Expect = 0.002
Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
Query: 130 KPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKS 189
K K + E + E + RK R+ K KRK +EE E+ +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 190 DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQT 249
+ +++ K+++E+ E EE R K + ++EE +EK++KR R
Sbjct: 64 RK--RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121
Query: 250 KE 251
K+
Sbjct: 122 KK 123
Score = 31.2 bits (69), Expect = 8.5
Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Query: 296 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSK 347
K++ ++KE E+ ++E +E+E++E +RK KE ++K + KT K
Sbjct: 2 KKKKKKKETEETEE--TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 67.8 bits (164), Expect = 8e-11
Identities = 62/222 (27%), Positives = 105/222 (47%), Gaps = 20/222 (9%)
Query: 134 KPRTPRRSKSDGEAKPEPSPSPRI-TRKSTRQTTITSHFAKGPAKRKPQEESERAKSDES 192
K R R AKP PS S R +++ T + T +H K P + +E K D+
Sbjct: 536 KQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPP--KVESKEKVMVKKDKP 593
Query: 193 IKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEP 252
IK E K ++ V S+E + P+ AE E+ + + + +E+ K+E +++ P
Sbjct: 594 IKTETKPSVTEKE-VPSKEEPS-PVKAEVAEKQATDVKPKAAKEKTVKKETKVK-----P 646
Query: 253 TPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK--RRPEEKEPEKV--- 307
K++ KE+P +E V ED+ +K+EK + + K K ++ E+KEP+K
Sbjct: 647 EDKKEEKEKPKKE----VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKK 702
Query: 308 -NPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKT 348
P +K+ ++E+K K KEP ++ K S T
Sbjct: 703 ETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Score = 58.9 bits (141), Expect = 4e-08
Identities = 67/292 (22%), Positives = 121/292 (41%), Gaps = 54/292 (18%)
Query: 65 ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD 124
+TKL++ S E K L +K + E+ + E +V +
Sbjct: 532 QTKLKQRADSRESLKPAAKPLPSKSVRKES----------------KEETPEVTKVNHVE 575
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEES 184
PPK SK + K D K E PS +T K S A+++ +
Sbjct: 576 --KPPKVESKEKV--MVKKDKPIKTETKPS--VTEKEVPSKEEPSPVKAEVAEKQATDVK 629
Query: 185 ERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKR 244
+A ++++K+E K + E ++ EE E+ K ++++ +KEEK
Sbjct: 630 PKAAKEKTVKKETKVKPEDKK--------------EEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 245 LRSQTKEPTPKQKLKEE------------PDREARAGVQADEDED--GDEKDEKKH-RSQ 289
+ + K+ K+ KEE P +E + V+ +E ++ +EK+ KK +
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKL 735
Query: 290 PKDLAAKRRP--EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 339
PKD P E K+P + P++ +K+E K++ PKE + K+ +
Sbjct: 736 PKDAKKSSTPLSEAKKPAALKPKV-PKKEESVKKDSVAAGKPKEKGKIKVIK 786
Score = 53.5 bits (127), Expect = 2e-06
Identities = 44/166 (26%), Positives = 78/166 (46%), Gaps = 11/166 (6%)
Query: 179 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD 238
K + +RA S ES+K K K R S+E E+ + E +E+
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKP---PKVESKEKVM 587
Query: 239 EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQAD-EDEDGDEKDEKKHRSQPKDLAAKR 297
K++K ++++TK P KE P +E + V+A+ ++ + K + + K
Sbjct: 588 VKKDKPIKTETK---PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKV 644
Query: 298 RPEEKEPEKVNPQISDEKDED----EKEEKRRKTTPKEPTEKKMAR 339
+PE+K+ EK P+ K ED +KEEK +K K+ +K++ +
Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKK 690
Score = 40.0 bits (92), Expect = 0.018
Identities = 70/353 (19%), Positives = 129/353 (36%), Gaps = 39/353 (11%)
Query: 3 ARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLC 62
A PA+ +S P+D+ + ++L+ + + + +K +L L+ +
Sbjct: 815 AAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIED----------- 863
Query: 63 DLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGM 122
E KL++ E E Y+ + + + K + E G E + + G+
Sbjct: 864 --EEKLKETE-PVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGV 920
Query: 123 ADANS-PPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQ 181
D + + + +A+ E + P + H +K P
Sbjct: 921 DDIEKFEDEGAGFEESSETGDYEEKAETEEAEEP--------EEDGEEHVCVSASKHSPT 972
Query: 182 EESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 241
E+ E AK+ E D EKR V S + A E+ + A E+ EE ++E
Sbjct: 973 EDEESAKA-----EADAYIREKRESVASGDDRAE----EDMDEAIEKGEAEQSEEEADEE 1023
Query: 242 EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK---RR 298
+K ++ +E P+ K E + A V + G E+ + K L A+ R
Sbjct: 1024 DKAEDAREEEYEPE---KMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGRE 1080
Query: 299 PEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPP 351
P ++ P E + +E+ R+ P+E T T+ S P
Sbjct: 1081 PASSIHDETLPG-GSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTP 1132
Score = 38.5 bits (88), Expect = 0.053
Identities = 67/327 (20%), Positives = 122/327 (37%), Gaps = 54/327 (16%)
Query: 58 KNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLS-LENGAHAYNREVNGRLENGNQARSE 116
K + ETK++ E+ EE K + +D + ++ EV ++ + +
Sbjct: 634 KEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEK 693
Query: 117 ARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPA 176
+PPK + K K + + EP + K ++++ AK PA
Sbjct: 694 KEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPA 753
Query: 177 KRKPQEESERAKSDESIKEED----KDQDEKRRRVTSRE--------------------- 211
KP+ K +ES+K++ K +++ + +V +E
Sbjct: 754 ALKPKV----PKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVM 809
Query: 212 ---RVARPLPAEEPERAKSGTRTEKEEERDEKE--------EKRLRSQTKEPTPKQKLKE 260
+A PA+E E +S + ++ +D +E K ++ Q + ++KLKE
Sbjct: 810 AAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKE 869
Query: 261 EPDREARAGVQADEDEDGD-EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDE 319
EA + E G E ++ + + ++ PEE EP + EK EDE
Sbjct: 870 TEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDE 929
Query: 320 ------------KEEKRRKTTPKEPTE 334
EEK +EP E
Sbjct: 930 GAGFEESSETGDYEEKAETEEAEEPEE 956
Score = 37.7 bits (86), Expect = 0.091
Identities = 76/403 (18%), Positives = 150/403 (37%), Gaps = 88/403 (21%)
Query: 21 PDDVRRRLKDLERDSLTEKEC---VKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEG 77
P+D ++ K+ + + +KE +K++ E ++ E+K ++ E K K+E+ +E
Sbjct: 646 PED-KKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Query: 78 YLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRT 137
+VK + K+ E +E + + +A++ + + KP+
Sbjct: 705 PPKEVKKEVKKEEKKE-----VKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKV 759
Query: 138 PRRSKS---DGEA--KPEPSPSPRITRKS------------TRQTTITSHFAKG-----P 175
P++ +S D A KP+ ++ +K T TT A G P
Sbjct: 760 PKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGP 819
Query: 176 AKRKPQEES------ERAKSDESIKEEDKD------------QDEKRRRVTS-------- 209
AK E S + K E +K E+ D +DE++ + T
Sbjct: 820 AKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQ 879
Query: 210 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPK-------------- 255
+ER PAE P+ + T E E E+ +E + + Q + K
Sbjct: 880 KEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSET 939
Query: 256 --------QKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR---------R 298
+ EEP+ + V + +DE+ +++ ++ R
Sbjct: 940 GDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDR 999
Query: 299 PEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341
EE E + +++ +E+ EE + + +E E + A+
Sbjct: 1000 AEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAE 1042
Score = 32.7 bits (73), Expect = 2.9
Identities = 38/212 (17%), Positives = 75/212 (35%), Gaps = 7/212 (3%)
Query: 182 EESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 241
E+ E +S+E EEDK +D + + A ++A E++
Sbjct: 1009 EKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTP 1068
Query: 242 EKRLRSQTKEPTPKQKLKEE--PDREARAGVQADEDEDGDEKDE----KKHRSQPKDLAA 295
K+L +Q+ P + +E P +DE+ D+ +E + ++++
Sbjct: 1069 TKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISS 1128
Query: 296 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQ 355
+ P + E +SDE + +E E ++ E + + + P
Sbjct: 1129 EPTPMD-EMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFS 1187
Query: 356 CGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLS 387
G D D K + P + +K S
Sbjct: 1188 EGSKTDATDGKDYNASASTISPPSSMEEDKFS 1219
Score = 32.0 bits (71), Expect = 5.0
Identities = 49/233 (21%), Positives = 84/233 (36%), Gaps = 54/233 (23%)
Query: 127 SPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 186
+PP +S+ S++D + PE P IT A ++ESE
Sbjct: 2145 TPPTSVSESAP---SQTDSDVPPETEECPSIT---------------ADANIDSEDESET 2186
Query: 187 AKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR 246
+D+++ + D + S + +PE K ++D KE +
Sbjct: 2187 IPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKE----K 2242
Query: 247 SQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE--EKEP 304
++TK+P K K KK + K LAA +P ++
Sbjct: 2243 TKTKKPGTKTK---------------------SSSPVKKSDGKSKPLAASPKPAGLKESS 2281
Query: 305 EKVNPQISDEKDEDEKEEKRRKTTP---------KEPTEKKMARAKTVMNSKT 348
+KV+ S +K E ++ + TTP K+ K A A ++KT
Sbjct: 2282 DKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKT 2334
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 67.0 bits (162), Expect = 1e-10
Identities = 83/378 (21%), Positives = 159/378 (42%), Gaps = 54/378 (14%)
Query: 26 RRLKDLERDSLTEKECVKEKLNLLHEFLQTE--IKNQLCDLETKLRKEELSEEGYLAKVK 83
RR + L R+ +E +E+ HE + E +K + + L++EE +E + K
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKP-RTPRRSK 142
L +D E E R E + + RR K + R +R +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 143 SDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQE------ESERAKSDESIKEE 196
S+ + + E K + + + KR+ +E + E + + +K E
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 197 DKDQDEKR------RRVTSRERVARPLPAEEP--ERAKSGTRTEKEEER---------DE 239
+++ E+R R+ ER + L EEP ER + ++E++EER E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED-----------------GDEKD 282
+ E+RL+ + +E +Q+LK E + E R A+E+++ E D
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
Query: 283 EKKHR--SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK-------EEKRRKTTPKEPT 333
++ + S+P+ +RR +E+E ++ + + E+E+ EE+RR T +
Sbjct: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQA 773
Query: 334 EKKMARAKTVMNSKTHPP 351
E+K R + ++++ PP
Sbjct: 774 EEKSERGRQRLSAR--PP 789
Score = 63.5 bits (153), Expect = 2e-09
Identities = 63/320 (19%), Positives = 143/320 (44%), Gaps = 25/320 (7%)
Query: 24 VRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVK 83
+RR+ ++ R+ E+ +E+ E + +++ + + + R+++L E + +
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRRE----QEERREQQLRREQEEERRE 361
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
L ++ E RE R E + + RR + + R ++ +
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 144 DGEAKPEPSPSPRITR--KSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD 201
+ + + E + + R+ + + K +EE+ER + + ++ +DQ+
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 202 EKRRRVTSRERVARPLPAEEPERAKSGTRTEKE--EERDEKEEKRLRSQTKEPTPKQKLK 259
E+RR R L EE ER + R E++ E++E+ E+RL+ Q +E +Q+L+
Sbjct: 482 EERRE--------RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 260 EEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDE 319
E ++ R + ++ ++EK+ + ++ KR EE+ + + K E+E
Sbjct: 534 SE--QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL-------KREEE 584
Query: 320 KEEKRRKTTPKEPTEKKMAR 339
+ ++R K +E E+++ R
Sbjct: 585 RRQQRLKREQEERLEQRLKR 604
Score = 61.2 bits (147), Expect = 8e-09
Identities = 65/309 (21%), Positives = 139/309 (44%), Gaps = 20/309 (6%)
Query: 33 RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSL 92
R +L K ++E+L + LQ E + +L E + R+ + E Y + + ++ L
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEE-EEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 93 ENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSK--SDGEAKPE 150
RE R E Q R + + + +P + R R K + E + E
Sbjct: 945 RE-----EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 151 PSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSR 210
R R+ R+ + K K + Q+E E+ +E K ++++ + R
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRK---KDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 211 ERVARPLPAEEPE---RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREAR 267
++ L EE E R + + KEEE ++EE+ LR + P+++ ++E +R+ R
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE-----PEKRRRQERERQCR 1111
Query: 268 AGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT 327
+ ++E+ ++E++ R + ++L + R EE+ ++ + +E ++ ++E R+
Sbjct: 1112 EEEELQQEEEQLLREEREKRRR-QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 328 TPKEPTEKK 336
+E +++
Sbjct: 1171 REEEELQQE 1179
Score = 60.5 bits (145), Expect = 1e-08
Identities = 70/355 (19%), Positives = 146/355 (41%), Gaps = 42/355 (11%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE------------ 72
RR L +L R EK+ +++ Q E + + ET LRKEE
Sbjct: 212 RRELLELRRKGREEKQ--QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 73 -LSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKP 131
L EE +++ L ++L E ++ R + + + E RR + +
Sbjct: 270 ELQEEE--EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 132 LSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE 191
+ R + E + R ++ R+ + + + ++ + ++
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 192 SIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEER------DEKEEKRL 245
++ E + + E++ R + R + L E+ R + R E+EEER E+ E+RL
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 246 RSQTKEPTP----------------KQKLK---EEPDREARAGVQADEDEDGDEKDEKKH 286
+ + +E KQ+LK EE RE ++ +E + E+ E++
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
Query: 287 RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341
R + ++ +R ++E E++ ++ E+ ++E+RR+ K EK++ + +
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Score = 58.9 bits (141), Expect = 4e-08
Identities = 84/405 (20%), Positives = 172/405 (42%), Gaps = 74/405 (18%)
Query: 22 DDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAK 81
D RRR ++ RD + +E+ H T K L E+ L K
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRH---------------TLYAKPALQEQ--LRK 901
Query: 82 VKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRS 141
+ LL ++ E RE R E Q R E + + L + +R
Sbjct: 902 EQQLLQEE---EEELQREEREKRRRQEQERQYREEEQ------LQQEEEQLLREEREKRR 952
Query: 142 KSDGEAKPEPSPSPRITRKSTR-QTTITSHFAKGPAKRKPQEESERAKSDESIKEED--- 197
+ + E R RK + Q + P KR+ QE ++ + +E +++E+
Sbjct: 953 RQERE---------RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Query: 198 -KDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE-RDEKEEKRLRSQTKEPTPK 255
+++ EKRRR E R K + E+E+ R+E+E++RL+ + ++ +
Sbjct: 1004 LREEREKRRRQEW----------ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 256 QKLKEEPD------REARAGVQAD----EDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPE 305
++L++E + RE R + + ++E+ +++E+ R +P+ KRR +E+E +
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE----KRRRQERERQ 1109
Query: 306 -KVNPQISDEKDE---DEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLD 361
+ ++ E+++ +E+E++RR+ ++ E++ + + + P K +
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK-----RRRQ 1164
Query: 362 DPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHK 406
+ + +Y + +E Q+L E+ E + E L + K
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 58.5 bits (140), Expect = 5e-08
Identities = 72/353 (20%), Positives = 148/353 (41%), Gaps = 44/353 (12%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLC------DLETKLRKEELSEEGY 78
+RR ++LER E+E +E+ LL E + + + +L+ + RK+ +E
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
Query: 79 LAKVK---SLLNKDLSLENGAHAYNREVNG-RLENGNQARSEARRVGMADANSPPKPLSK 134
+ +K ++ +N + RE R +Q R + + + +
Sbjct: 1220 RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
Query: 135 PRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIK 194
+ RR + PE R +K ++ S K + + +E+ R ++D +
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 195 EEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE---------KEEKRL 245
EE++ E+ + R+ R EE + G + +EE+R KEE++L
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 246 RSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEK------------DEKKHRSQPKDL 293
R Q +E Q+L+++ DR+ R Q ++ D K E+K + + L
Sbjct: 1400 RCQERE----QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 294 AAKRRP---------EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKM 337
+R +E+E ++++ Q D K +E+++ RR+ ++ E+++
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Score = 57.8 bits (138), Expect = 8e-08
Identities = 60/301 (19%), Positives = 130/301 (43%), Gaps = 35/301 (11%)
Query: 56 EIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNR----EVNGRLENGN 111
E K CD + L ++ EE + +D LE R E L G
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQ----RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPR-------ITRKSTRQ 164
+ + R+ D + L + R + + + A+ E S + + R+
Sbjct: 153 EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR 212
Query: 165 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 224
+ KG R+ +++ R + D +EE++ + KR V +E L EEP+R
Sbjct: 213 RELLELRRKG---REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE--EKLQEEEPQR 267
Query: 225 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ---ADEDEDGDEK 281
+ E E+EE+ + + +E +++ +E+ + R Q E+E +++
Sbjct: 268 ---------QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 282 DEKKHRSQPKDLAAKRRPEE---KEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
+E++ + + ++ +RR ++ ++ E+ Q+ E++E+ +E++ R+ +E E+++
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 339 R 339
R
Sbjct: 379 R 379
Score = 55.1 bits (131), Expect = 5e-07
Identities = 79/383 (20%), Positives = 162/383 (42%), Gaps = 57/383 (14%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
+RRL++ ER E+E +E+ LL E +T + +L E + RKEE ++ + +
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL---ERQYRKEEELQQ----EEEQ 1092
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSD 144
LL ++ E R E Q R E + + L + +R + +
Sbjct: 1093 LLREE-----------PEKRRRQERERQCREEE------ELQQEEEQLLREEREKRRRQE 1135
Query: 145 GEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKD--QDE 202
E + + Q + P KR+ QE + + +E +++E++ ++E
Sbjct: 1136 LERQ--------YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 203 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD--------EKE----EKRLRSQTK 250
+ +R RER R EE +R K R E++R EKE + ++ + +
Sbjct: 1188 QEKRRQERERQYRE--EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 251 EPTPKQKLKEEP--DREARAGVQ--ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEK 306
E ++L++ DR+++ +Q E ++ D + E++ R Q +D + + E+
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR-RWQQRDRHFPEEEQLEREEQ 1304
Query: 307 VNPQISDEKDEDEK----EEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDD 362
+ D K ++EK EE+ K +E K + + + P + + + +
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 363 PDLKYGQHPPDAVDEPQMLTNEK 385
+L++ + ++E Q L ++
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQE 1387
Score = 55.1 bits (131), Expect = 5e-07
Identities = 73/360 (20%), Positives = 151/360 (41%), Gaps = 28/360 (7%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE--LSEEGYLAKV 82
+RR ++ ER E+E +E+ LL E + K + +LE + R+EE EE L +
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREERE---KRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 83 KSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSK 142
+ + LE + E+ E + E RR + L + + +R +
Sbjct: 1157 EPEKRRRQELER-QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 143 SDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESI------KEE 196
+ + + R + + R+ ++ R + + +++
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Query: 197 DKDQDEKRRRVTSRER---VARPLPAEEPERAKSGTRTEKEEE---RDEKEEKRLRSQT- 249
++D++++RRR R+R L EE + AK R +EE+ R+E+EEKR R +T
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD 1335
Query: 250 ----KEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEE--KE 303
+E Q+ +E+P R + E+E ++ +K + + L + R + KE
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 304 PEKVNPQISDEK---DEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYL 360
+++ Q +++ D D K + + ++ ++K + + + K ++ Q L
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Score = 53.9 bits (128), Expect = 1e-06
Identities = 46/180 (25%), Positives = 86/180 (47%), Gaps = 20/180 (11%)
Query: 170 HFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGT 229
++A G A +E+ R ES+ ++ + + E +RR R+R EEP + +
Sbjct: 86 YYALGQATGLDEEKRARCDGKESLLQDRRQE-EDQRRFEPRDRQLE----EEPGQRRRQK 140
Query: 230 RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEK-------- 281
R E+E E E EE+ + + E +Q+ EE R+ + + +E +E+
Sbjct: 141 RQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHE 200
Query: 282 ------DEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEK 335
+E+ R + +L K R EEK+ ++ Q ++E+EKE ++R+T ++ EK
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGR-EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Score = 53.5 bits (127), Expect = 2e-06
Identities = 83/407 (20%), Positives = 169/407 (41%), Gaps = 65/407 (15%)
Query: 21 PDDVRRR--LKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGY 78
P++ RR+ LK E++ +++ +E+ + L+ E + + + K EE E
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 79 LA---------KVKSLLNK-DLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSP 128
LA ++KS + K LE+ A A +V R R +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 129 PKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEE---SE 185
+ R + + E + + + + KS R S A+ P + + + + E
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS--ARPPLREQRERQLRAEE 802
Query: 186 RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEP----ERAKS------------GT 229
R + ++ E+++++++RR+ RE+ + L EE ERA+
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862
Query: 230 RTEKEEERDEK------EEKRLRSQT--KEPTPKQKLKEEPDREARAGVQADEDEDGDEK 281
R +E+ RD+K EE++ R T +P +++L++E +Q +E+E E+
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL-----LQEEEEELQREE 917
Query: 282 DEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE---DEKEEKRRKTTPKEPTEKKMA 338
EK +RR E++ + Q+ E+++ +E+E++RR+ ++ + K
Sbjct: 918 REK-----------RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 339 RAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEK 385
+ K P K + + + KY + +E Q+L E+
Sbjct: 967 QQKEEQLLGEEPEK-----RRRQEREKKYREEEELQQEEEQLLREER 1008
Score = 52.8 bits (125), Expect = 3e-06
Identities = 62/309 (20%), Positives = 135/309 (43%), Gaps = 46/309 (14%)
Query: 43 KEKLNLLHEFLQTEIKNQLCDL-----ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAH 97
+E LL E + ++ Q D E +LR++E ++ + + ++ L+ G
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 98 AYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRI 157
R R E + R E +++ + K L + + RR + + + + E
Sbjct: 1682 QQLR----RQERDRKFREEEQQLRRQERER--KFLQEEQQLRRQELERKFREE------- 1728
Query: 158 TRKSTRQTTITSHFAKGPAKRKPQEESERA--KSDESIKEEDKDQDEKRRRVTSRERVAR 215
+ RQ T + RK EE + + ++ ++ +++D+ + +ER +
Sbjct: 1729 --EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 216 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKE------------PTPKQKLKEEPD 263
L ++E +R E+E+ R E+EE++LR Q ++ +Q+L++E D
Sbjct: 1787 QLRSQESDRKFR----EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 264 REARAGVQ--------ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEK 315
R+ RA Q +E E E+++K+ + + + L + +++ E+ + Q+ + K
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
Query: 316 DEDEKEEKR 324
++ K R
Sbjct: 1903 SQEGKGHGR 1911
Score = 51.2 bits (121), Expect = 8e-06
Identities = 43/172 (25%), Positives = 91/172 (52%), Gaps = 22/172 (12%)
Query: 181 QEESERAKSDESIKEE----DKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE 236
QE+ ER +S E +++ +++ KRRR T + PA + + K ++EEE
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK-----PALQEQLRKEQQLLQEEEE 911
Query: 237 R---DEKEEKRLRSQTKEPTPKQKLKEEPD---REARAGVQADEDEDGDEKDEKKHRSQP 290
+E+E++R + Q ++ +++L++E + RE R + E E KD+K + +
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 291 KDLA---AKRRPEEKEPE-KVNPQISDEKDE---DEKEEKRRKTTPKEPTEK 335
+ L KRR +E+E + + ++ E+++ +E+E++RR+ ++ +K
Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Score = 48.9 bits (115), Expect = 4e-05
Identities = 64/328 (19%), Positives = 139/328 (42%), Gaps = 23/328 (7%)
Query: 20 LPDDVRRRLKDLERDSLTEKECVK--EKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEG 77
L ++ R R ++ ER L E++ ++ E+ L + + + + L + R + EE
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436
Query: 78 YLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRT 137
+ + K L E +E + + Q E + K L + +
Sbjct: 1437 QQVRRQERERKFLEEEQ---QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 138 PRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEED 197
RR + D + + + S RK + + +RK +E ++ + E ++
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEE---QQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 198 KDQDEKRRRVTS--RERVARPLPAEEPERA----KSGTRTEKEEERDEKEEKRLRSQTKE 251
+D+D K R +ER + L +E +R + R +++E + ++E++LR Q +
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 252 PTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 311
Q+L++E DR+ R DE + ++++ HR + + P+ + E+ Q+
Sbjct: 1611 ----QQLRQERDRKFR----EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER-EQQL 1661
Query: 312 SDEKDEDEKEEKRRKTTPKEPTEKKMAR 339
++D +EE++ +E ++ R
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Score = 48.5 bits (114), Expect = 5e-05
Identities = 68/334 (20%), Positives = 136/334 (40%), Gaps = 61/334 (18%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
+RR ++ ER + E +E+ LL E + K +L + E + R+EE ++ + +
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREERE---KRRLQERERQYREEEELQQ----EEEQ 1062
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSD 144
LL ++ RE R E Q R E + +P + R R +
Sbjct: 1063 LLGEE-----------RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Query: 145 GEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKR 204
E + + + R+ +E+ R + + +EE++ Q E+
Sbjct: 1112 EEEELQQEEEQLL--------------------REEREKRRRQELERQYREEEEVQQEEE 1151
Query: 205 RRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR 264
+ + R E R + + E+E+ E++EKR + + ++ + +EE R
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ----YREEEELQR 1207
Query: 265 EARAGVQADEDEDGDEK----DEKKHRSQPKDLAAKRRPEEKEPEKVNPQISD------- 313
+ R DED+ D K EK++ + + K R E+ + + Q+ D
Sbjct: 1208 QKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL 1267
Query: 314 -----EKDEDEKEEKRRKTTPKE---PTEKKMAR 339
E+ E ++E++RR+ ++ P E+++ R
Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/182 (20%), Positives = 84/182 (46%), Gaps = 26/182 (14%)
Query: 181 QEESERAKSDESIKEEDKD--QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE-- 236
+++ R + D +EE++ + E+ R+ E+ R E R + R E E+E
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 237 ---------------RDEKEEKRLRSQTKEP--TPKQKLKEEPDREARAGVQAD-----E 274
R E+EE++LR Q ++ +++L++E + + ++D E
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 275 DEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 334
++ E++E++ R Q +D + E+ + E+ ++ E+D + E++ T K E
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 335 KK 336
++
Sbjct: 1861 EQ 1862
Score = 47.4 bits (111), Expect = 1e-04
Identities = 65/316 (20%), Positives = 135/316 (42%), Gaps = 24/316 (7%)
Query: 26 RRLKDLE-RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R+ ++ E R E++ ++E+ L + Q + + E +LR++E ++ + +
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE----EQQLRRQERGQQRRQDRDRK 1556
Query: 85 LLNKD-LSLENGAHAYNREVNGR---LENGNQARSEARRVGMADANSPPKPLSKPRTPRR 140
++ L E +R+ R LE R E R M D + + + R+
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL-RQ 1615
Query: 141 SKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESE-RAKSDESIKEEDKD 199
+ + E R ++ RQ + P R+ + E + R D +EE++
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL 1675
Query: 200 QDEKRRRVTSRERVARPLPAEEP-----ERAKSGTRTEKEEERDEKEEK-RLRSQTKEPT 253
E + R+ R EE ER + + E++ R E E K R Q ++ T
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
Query: 254 PKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE---EKEPEKVNPQ 310
+++L+ R+ R +E++ E++E++ R Q +D + + E+E +++ Q
Sbjct: 1736 EQEQLR----RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 311 ISDEKDEDEKEEKRRK 326
SD K +E++ ++ +
Sbjct: 1792 ESDRKFREEEQLRQER 1807
Score = 44.7 bits (104), Expect = 7e-04
Identities = 59/293 (20%), Positives = 120/293 (40%), Gaps = 26/293 (8%)
Query: 51 EFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENG 110
+FL+ E + + + + K R++EL + K L E H R+ E
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQ-------EPERKFLEEEQQLHRQQRQRKFLQEEQ 1538
Query: 111 NQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSH 170
R E + D + + + R R + ++ E R+ + R+
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ--LSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 171 FAKGPAKRKPQEESE--RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSG 228
F + + + QE + R + D +E+++ E+ + R+ R EEP+ +
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656
Query: 229 TRTEKEEERDEK--EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKH 286
+ +RD K EE++L + +E +++ ++ RE ++ E E ++E++
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 287 RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 339
R Q +L K R EE+ + E E+E+ RR+ ++ E++ R
Sbjct: 1717 RRQ--ELERKFREEEQL-----------RQETEQEQLRRQERYRKILEEEQLR 1756
Score = 44.3 bits (103), Expect = 0.001
Identities = 43/184 (23%), Positives = 86/184 (46%), Gaps = 20/184 (10%)
Query: 171 FAKGPAKRKPQEESERAKSDESIKEEDKDQD----EKRRRVTSRERVARPLPAEEPERAK 226
F + + + QE + + +E +++E + + E+ R++ E++ RP E+ R +
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL-RPEREEQQLRRQ 1767
Query: 227 SGTRTEKEEE--RDEKEEKRLRSQTKEPTPKQKLKEEPD-REARAGVQA-DEDEDGDEKD 282
R +EEE R E+EE++LRSQ + +K +EE R+ R Q + DG +
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESD----RKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 283 EKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE-------DEKEEKRRKTTPKEPTEK 335
E++ + R+ +++ + EK E+E+KRR+ ++ E+
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 336 KMAR 339
+ R
Sbjct: 1884 HIRR 1887
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/186 (23%), Positives = 89/186 (47%), Gaps = 20/186 (10%)
Query: 163 RQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRE-RVARPLPAEE 221
RQ ++ RK + E ++ + E ++ +D+ + RR+ ++ R R E
Sbjct: 1564 RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE 1623
Query: 222 PERAKSGTRTEK--EEERDEK---EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDE 276
E+ ++ +ERD K EE +LR Q +E Q+L+ + DR+ R +E++
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE----QQLRHDRDRKFR-----EEEQ 1674
Query: 277 DGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
E +E++ R Q +D R +E +++ Q + K E+++ RR+ ++ E++
Sbjct: 1675 LLQEGEEQQLRRQERD-----RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 337 MARAKT 342
R +T
Sbjct: 1730 QLRQET 1735
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/160 (21%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 201 DEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE------RDEKEEKRLRSQTKEPTP 254
+EKR R +E + + EE +R + EEE + +E++R ++ +E +
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 255 KQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP----KDLAAKRRPEEKEPEKVNPQ 310
KQ+ E+ DR+ R + ++ E++E++ + K + P+E++ +
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 311 ISDEKDEDEKEEKRRKTTPK---EPTEKKMARAKTVMNSK 347
K +EK+++RR+ + E EK+ + +TV+ +
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 67.0 bits (162), Expect = 1e-10
Identities = 69/321 (21%), Positives = 132/321 (41%), Gaps = 22/321 (6%)
Query: 33 RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSL 92
R+ L E+ E N ++EI+N ++ R EL E+G S ++ S
Sbjct: 531 RNHLREESSRTEIRNESRNESRSEIRNDRMG-RSRGRVPELPEKGSRGSRGSQIDSHSSN 589
Query: 93 ENGAHAYN-------REVNGRLENGNQARSEA--RRVGMADANSPPKPLSKPRTPRR--S 141
N ++ R+ +N +QAR + RR G D + +P +P R
Sbjct: 590 SNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQG 649
Query: 142 KSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD 201
++D + E R+ R R + R+ E ER + E +E ++D++
Sbjct: 650 RNDELERDERREERRVDRVDDR---------RDERARERDRERERDRERERERERERDRE 700
Query: 202 EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEE 261
++ R RER E ER + R + E+E +R R + +E +++ +E
Sbjct: 701 REKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERER 760
Query: 262 PDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEP-EKVNPQISDEKDEDEK 320
R + E E E+D+++ R + + K R + +E E++ + DE+
Sbjct: 761 ERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER 820
Query: 321 EEKRRKTTPKEPTEKKMARAK 341
+ K+R P+ ++ + +
Sbjct: 821 KSKKRYRNEGSPSPRQSPKRR 841
Score = 47.8 bits (112), Expect = 9e-05
Identities = 83/357 (23%), Positives = 144/357 (40%), Gaps = 53/357 (14%)
Query: 22 DDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAK 81
D R + ++LER+ E+E +EK E + +++ D E + R+ E E +
Sbjct: 698 DREREKERELERERAREREREREK-----ERDRERDRDRDHDRERE-RERERDREKERER 751
Query: 82 VKSLLNKDLSLENGAHAYNREVNGRLENGNQARS-----EARRVGMADANSPPKPLSKPR 136
+ ++ E R ++ R E + G D + + + R
Sbjct: 752 EREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Query: 137 TPR----RSKSDGEAKPEPSPSPRITRKSTRQTTITSH-FAKGPAKR----------KPQ 181
PR KS + E SPSPR + K R+ + S + G K +PQ
Sbjct: 812 NPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ 871
Query: 182 EESERAKS--DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
E + S E + K++D K R S R EE E + + +K+ E+ E
Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRY------EEQELKEKVSSVDKQREQTE 925
Query: 240 -KEEKRLRSQTKEPTPKQKLKEEPDR-----EARAGVQ------ADEDEDGDEKDEKKHR 287
E R+R+Q + + +E DR + +A +Q ED+ G E+ +
Sbjct: 926 ILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETT 985
Query: 288 SQ------PKDLAAKRRPEEK-EPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKM 337
S+ PK K+ E+K + K + ISDE+ + ++KR TP T++++
Sbjct: 986 SEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEEL 1042
Score = 39.3 bits (90), Expect = 0.031
Identities = 43/202 (21%), Positives = 84/202 (41%), Gaps = 13/202 (6%)
Query: 127 SPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTR---QTTITSHFAKGPAKRKPQEE 183
+PP S P S S + K P R+ R + T SH + + + +
Sbjct: 364 TPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGK 423
Query: 184 SERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEK 243
+R K +E ++DQ R RE P + +R + ++ E RD ++ +
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDRE------PRDGRDRRDARDTRDRRELRDSRDMR 477
Query: 244 RLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD-EKKHRSQPKDLAAKRRPEEK 302
R + ++ + K +P R++R+ A + D + +D +K + P++ + R +
Sbjct: 478 DSR-EMRDYSRDTKESRDP-RDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLR 535
Query: 303 EPEKVNPQISDEKDEDEKEEKR 324
E E +I +E + + E R
Sbjct: 536 E-ESSRTEIRNESRNESRSEIR 556
Score = 38.5 bits (88), Expect = 0.053
Identities = 54/253 (21%), Positives = 90/253 (35%), Gaps = 43/253 (16%)
Query: 94 NGAHAYNREVNGR---LENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPE 150
+ AH + +GR L +G++ R + + + + K P RS S
Sbjct: 1212 DSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 1271
Query: 151 PSPSPRITRKSTRQTTITSHFAKGPAKRKPQE--------ESERAKSDESIKEEDKDQDE 202
S R + +S RQ + S ++ + QE E ER + D +E D+D D+
Sbjct: 1272 SHSSRRSSPESDRQ--VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK 1329
Query: 203 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP 262
R R+R+ +E ER+ + +KR + L E
Sbjct: 1330 DWPRNRDRDRL-------------------RERERERERDKR-----------RDLDRER 1359
Query: 263 DREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEE 322
+R V+ D D D D E K AK E + + + S D++ ++
Sbjct: 1360 ERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDK 1419
Query: 323 KRRKTTPKEPTEK 335
E T K
Sbjct: 1420 DLGSVQGFEETNK 1432
Score = 36.2 bits (82), Expect = 0.26
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 24/174 (13%)
Query: 168 TSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKS 227
T F GP+ R S +S E + +++ + +R+ E R +S
Sbjct: 56 TCRFVHGPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKR-------NTEES 108
Query: 228 GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR 287
+ KE R EK TKE TP E + D+ ++GD + H
Sbjct: 109 SSPVRKESSRGRHREKEDIKITKERTP-----ESEEENVEWETNRDDSDNGDINYDYVHE 163
Query: 288 SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341
L KR+ ++E K+ E E EKR + K+ ++ R+K
Sbjct: 164 ---LSLEMKRQKIQRELMKL---------EQENMEKREEIIIKKEVSPEVVRSK 205
Score = 34.7 bits (78), Expect = 0.77
Identities = 63/347 (18%), Positives = 130/347 (37%), Gaps = 48/347 (13%)
Query: 24 VRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVK 83
++R L LE++++ ++E + K + E +++++ LRK S + +
Sbjct: 173 IQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPS-----PSLRKSSKSPKRKSSPKS 227
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENG--NQARSEARRVGMADANSPPKPLS-------- 133
S +K + A + + + N NQ++ + R SPP P+
Sbjct: 228 SSASKK---DRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP-----SPPPPIPEDIALGKK 279
Query: 134 -------KPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 186
K R +++ DG+ + R R R T+ + R S
Sbjct: 280 YKEKYKVKDRIEEKTR-DGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSR---HHSSS 335
Query: 187 AKSDESIKEEDKDQDEKRRRVTSRERV--------ARPLPAEE---PERAKSGTR--TEK 233
++S SI+ KR S +R A P P+ P+R +S R +
Sbjct: 336 SQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPM 395
Query: 234 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDL 293
E+ E+ +S + ++ + + DRE + + + ++D + + +P+D
Sbjct: 396 REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG 455
Query: 294 AAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT-TPKEPTEKKMAR 339
+R + + D +D E + R T ++P + + R
Sbjct: 456 RDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 66.2 bits (160), Expect = 2e-10
Identities = 56/241 (23%), Positives = 109/241 (45%), Gaps = 20/241 (8%)
Query: 105 GRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKST-- 162
GRL + RS DA+ + + R +++ + + + R K T
Sbjct: 52 GRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNR 111
Query: 163 -----RQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 217
+QT I + +R+ Q+ ER + +E D+D++++R R T ++R +
Sbjct: 112 NRDREKQTEI-----ERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRE 166
Query: 218 PAEEPERAKSGTRTEKEEERD-EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDE 276
E ER + EK++ER+ E++ R R KE + + + R+ + Q + D
Sbjct: 167 TETERERDRE---REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Query: 277 DGD-EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEK 335
+G+ E D ++ R + +D +R ++E ++ + + K E +KE K +K K +K
Sbjct: 224 EGERETDRRRERQRDRDRGKER---DRERDRKEERKKERKKERKKERKEKKKEEKRREDK 280
Query: 336 K 336
K
Sbjct: 281 K 281
Score = 50.8 bits (120), Expect = 1e-05
Identities = 44/178 (24%), Positives = 79/178 (44%), Gaps = 13/178 (7%)
Query: 164 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 223
+ TI F++G R +ES R+ ++ D +R R RE+ + + +
Sbjct: 42 EVTIPLDFSRG---RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDR-K 97
Query: 224 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDE 283
R + R EKE R+ EK+ + KQK +E RE G + + D D +++ E
Sbjct: 98 RDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE---RERDRGRERERDRDREKERE 154
Query: 284 K---KHRSQPKDLAAKR---RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEK 335
+ K R ++ +R R EK+ E+ + D + + EKE +R+ ++ K
Sbjct: 155 RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRK 212
Score = 45.1 bits (105), Expect = 6e-04
Identities = 42/180 (23%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 100 NREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITR 159
+RE + + N+ R ++ + K + R R + + R T
Sbjct: 99 DRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTE 158
Query: 160 KSTRQTTITSHFAKGPAKRKPQEESE--------RAKSDESIKEEDKDQDEKRRRVTSRE 211
K T + +R+ Q+E E R E ++ D+++D +R+ T R+
Sbjct: 159 KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ 218
Query: 212 RVARPLPAEEPERAKSGTR-----TEKEEERDEKEE-KRLRSQTKEPTPKQKLKEEPDRE 265
R E +R + R E++ ERD KEE K+ R + ++ K+K KEE RE
Sbjct: 219 RETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRE 278
Score = 35.8 bits (81), Expect = 0.35
Identities = 47/224 (20%), Positives = 89/224 (39%), Gaps = 17/224 (7%)
Query: 23 DVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKV 82
D R+R +D R+ TEKE +++ + + N+ D E ++ E+ + K
Sbjct: 75 DDRQRERDRVREK-TEKERDRDRKRDRERRRKEKETNRNRDRE---KQTEIERDREREKQ 130
Query: 83 KSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSK 142
K ++ + G RE + E + ++E R G + + + R R K
Sbjct: 131 KG---RERERDRGRE---RERDRDREKERERQTEKDRDGQRETET-----ERERDREREK 179
Query: 143 SDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIK--EEDKDQ 200
R T K + T + + + Q E++R E+ + E +D+
Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
Query: 201 DEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKR 244
D + R R+R + ER K +KEE+R E ++++
Sbjct: 240 DRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 65.5 bits (158), Expect = 4e-10
Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 21/231 (9%)
Query: 124 DANSPPK-----PLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKR 178
D ++P K P K R P K KP S I ST+ I + A R
Sbjct: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
Query: 179 KPQ----EESERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPAEEPERAKSG 228
KP+ EE+ K D + EE K+++E + E + +PA P + +
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
Query: 229 TRTEKEEERDEKEEKRLR---SQTKEPTPKQKLKE-EPDREARAGVQADEDEDGDEKDEK 284
TE +E E+EE++ R Q + +Q+L+E EP+ E A + +++D D DE
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 285 K-HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 334
H K + +P +E K P + + + ++ R K KE TE
Sbjct: 1321 DGHLESTKKKELEEQP-TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370
Score = 53.1 bits (126), Expect = 2e-06
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 37/326 (11%)
Query: 108 ENGNQARSEARRVGMADA---NSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQ 164
EN R RR+ D S K SK D + P P + ++ +
Sbjct: 1076 ENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKN 1135
Query: 165 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRR----VTSRERVARPLPAE 220
+ + + K+K + + K K + K R V+++ V P+
Sbjct: 1136 SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPI-VS 1194
Query: 221 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDE 280
P+ + E EE + KE+ P P+++ KEE + +A A +A+E E+ D
Sbjct: 1195 IPKAGRKPKIQESEETVEPKEDM--------PLPEER-KEEEEMQAEA-EEAEEGEEEDA 1244
Query: 281 KDEKKHRSQPKDLAAKRRPEEKEP----EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+ + P D + E KEP E+ P++S+E + + EE++++ EP E++
Sbjct: 1245 ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEE--QRQSEEEQQELEEPEPEEEE 1302
Query: 337 MARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPP---DAVDEPQM--------LTNEK 385
A A+T N H G +L+ K + P D +EP + + +
Sbjct: 1303 DAAAETAQND-DHDADDEDDG-HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR 1360
Query: 386 LSIFDANESGFESYEALPQHKLTCFS 411
I D E+ +S E P H + S
Sbjct: 1361 EKIKDKEETELDSEEEQPSHDTSVVS 1386
Score = 42.7 bits (99), Expect = 0.003
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 16/186 (8%)
Query: 108 ENGNQARSEARRVGMA-DANSPPKPLSKPRTPRRSKSDGEAKPE---PSPSPRITRKSTR 163
E QA +E G DA S P + P S +PE PR++ + R
Sbjct: 1226 EEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ-R 1284
Query: 164 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 223
Q+ + P +P+EE + A + D D ++ +++++ P E
Sbjct: 1285 QSEEEQQELEEP---EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
Query: 224 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR------EARAGVQADEDED 277
+ + G + + +K ++++ KE T +E+P E AG + D +ED
Sbjct: 1342 KEEPGVQESFLDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 278 GDEKDE 283
K+E
Sbjct: 1400 SHTKEE 1405
Score = 32.0 bits (71), Expect = 5.0
Identities = 76/344 (22%), Positives = 129/344 (37%), Gaps = 57/344 (16%)
Query: 38 EKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSE-----EGYLAKVKSLLNKDLS- 91
+ E +E+ E L + D + L K LSE G L K L L+
Sbjct: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTE 964
Query: 92 -LENGAHAYNREVNGRLENGNQARSEARRVGMADANSPP---KPLSKPRTPRRSKSDGEA 147
E Y+ L +++ E ++SPP KP K + P +
Sbjct: 965 GSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVR 1024
Query: 148 KPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRV 207
K + S +T + T + + +P R + I EE++++DE +
Sbjct: 1025 KRKHHNSSVVTETISETTEVLDEPFEDSDSERPMP---RLEPTFEIDEEEEEEDENE--L 1079
Query: 208 TSRERVARPLPAEEPERAKSGT-RTEKEEERDEKEE----------------KRLRSQTK 250
RE R L +++ R +S + R K+EE DE+ + + +++
Sbjct: 1080 FPREYFRR-LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPL 1138
Query: 251 EP---TPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR----------------SQPK 291
EP TP +K K P ++R + + G + K R S PK
Sbjct: 1139 EPDTSTPLKKKKGWPKGKSRKPIHW-KKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPK 1197
Query: 292 DLAAKRRPEEKEPEK-VNPQISDEKDEDEKEEKRRKTTPKEPTE 334
A R+P+ +E E+ V P+ E+ KEE+ + +E E
Sbjct: 1198 ---AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEE 1238
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 65.5 bits (158), Expect = 4e-10
Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 21/231 (9%)
Query: 124 DANSPPK-----PLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKR 178
D ++P K P K R P K KP S I ST+ I + A R
Sbjct: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
Query: 179 KPQ----EESERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPAEEPERAKSG 228
KP+ EE+ K D + EE K+++E + E + +PA P + +
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
Query: 229 TRTEKEEERDEKEEKRLR---SQTKEPTPKQKLKE-EPDREARAGVQADEDEDGDEKDEK 284
TE +E E+EE++ R Q + +Q+L+E EP+ E A + +++D D DE
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 285 K-HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 334
H K + +P +E K P + + + ++ R K KE TE
Sbjct: 1321 DGHLESTKKKELEEQP-TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370
Score = 53.1 bits (126), Expect = 2e-06
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 37/326 (11%)
Query: 108 ENGNQARSEARRVGMADA---NSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQ 164
EN R RR+ D S K SK D + P P + ++ +
Sbjct: 1076 ENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKN 1135
Query: 165 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRR----VTSRERVARPLPAE 220
+ + + K+K + + K K + K R V+++ V P+
Sbjct: 1136 SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPI-VS 1194
Query: 221 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDE 280
P+ + E EE + KE+ P P+++ KEE + +A A +A+E E+ D
Sbjct: 1195 IPKAGRKPKIQESEETVEPKEDM--------PLPEER-KEEEEMQAEA-EEAEEGEEEDA 1244
Query: 281 KDEKKHRSQPKDLAAKRRPEEKEP----EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+ + P D + E KEP E+ P++S+E + + EE++++ EP E++
Sbjct: 1245 ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEE--QRQSEEEQQELEEPEPEEEE 1302
Query: 337 MARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPP---DAVDEPQM--------LTNEK 385
A A+T N H G +L+ K + P D +EP + + +
Sbjct: 1303 DAAAETAQND-DHDADDEDDG-HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR 1360
Query: 386 LSIFDANESGFESYEALPQHKLTCFS 411
I D E+ +S E P H + S
Sbjct: 1361 EKIKDKEETELDSEEEQPSHDTSVVS 1386
Score = 42.7 bits (99), Expect = 0.003
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 16/186 (8%)
Query: 108 ENGNQARSEARRVGMA-DANSPPKPLSKPRTPRRSKSDGEAKPE---PSPSPRITRKSTR 163
E QA +E G DA S P + P S +PE PR++ + R
Sbjct: 1226 EEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ-R 1284
Query: 164 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 223
Q+ + P +P+EE + A + D D ++ +++++ P E
Sbjct: 1285 QSEEEQQELEEP---EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
Query: 224 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR------EARAGVQADEDED 277
+ + G + + +K ++++ KE T +E+P E AG + D +ED
Sbjct: 1342 KEEPGVQESFLDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 278 GDEKDE 283
K+E
Sbjct: 1400 SHTKEE 1405
Score = 32.0 bits (71), Expect = 5.0
Identities = 76/344 (22%), Positives = 129/344 (37%), Gaps = 57/344 (16%)
Query: 38 EKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSE-----EGYLAKVKSLLNKDLS- 91
+ E +E+ E L + D + L K LSE G L K L L+
Sbjct: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTE 964
Query: 92 -LENGAHAYNREVNGRLENGNQARSEARRVGMADANSPP---KPLSKPRTPRRSKSDGEA 147
E Y+ L +++ E ++SPP KP K + P +
Sbjct: 965 GSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVR 1024
Query: 148 KPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRV 207
K + S +T + T + + +P R + I EE++++DE +
Sbjct: 1025 KRKHHNSSVVTETISETTEVLDEPFEDSDSERPMP---RLEPTFEIDEEEEEEDENE--L 1079
Query: 208 TSRERVARPLPAEEPERAKSGT-RTEKEEERDEKEE----------------KRLRSQTK 250
RE R L +++ R +S + R K+EE DE+ + + +++
Sbjct: 1080 FPREYFRR-LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPL 1138
Query: 251 EP---TPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR----------------SQPK 291
EP TP +K K P ++R + + G + K R S PK
Sbjct: 1139 EPDTSTPLKKKKGWPKGKSRKPIHW-KKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPK 1197
Query: 292 DLAAKRRPEEKEPEK-VNPQISDEKDEDEKEEKRRKTTPKEPTE 334
A R+P+ +E E+ V P+ E+ KEE+ + +E E
Sbjct: 1198 ---AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEE 1238
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 65.5 bits (158), Expect = 4e-10
Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 21/231 (9%)
Query: 124 DANSPPK-----PLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKR 178
D ++P K P K R P K KP S I ST+ I + A R
Sbjct: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
Query: 179 KPQ----EESERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPAEEPERAKSG 228
KP+ EE+ K D + EE K+++E + E + +PA P + +
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
Query: 229 TRTEKEEERDEKEEKRLR---SQTKEPTPKQKLKE-EPDREARAGVQADEDEDGDEKDEK 284
TE +E E+EE++ R Q + +Q+L+E EP+ E A + +++D D DE
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 285 K-HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 334
H K + +P +E K P + + + ++ R K KE TE
Sbjct: 1321 DGHLESTKKKELEEQP-TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370
Score = 53.1 bits (126), Expect = 2e-06
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 37/326 (11%)
Query: 108 ENGNQARSEARRVGMADA---NSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQ 164
EN R RR+ D S K SK D + P P + ++ +
Sbjct: 1076 ENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKN 1135
Query: 165 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRR----VTSRERVARPLPAE 220
+ + + K+K + + K K + K R V+++ V P+
Sbjct: 1136 SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPI-VS 1194
Query: 221 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDE 280
P+ + E EE + KE+ P P+++ KEE + +A A +A+E E+ D
Sbjct: 1195 IPKAGRKPKIQESEETVEPKEDM--------PLPEER-KEEEEMQAEA-EEAEEGEEEDA 1244
Query: 281 KDEKKHRSQPKDLAAKRRPEEKEP----EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
+ + P D + E KEP E+ P++S+E + + EE++++ EP E++
Sbjct: 1245 ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEE--QRQSEEEQQELEEPEPEEEE 1302
Query: 337 MARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPP---DAVDEPQM--------LTNEK 385
A A+T N H G +L+ K + P D +EP + + +
Sbjct: 1303 DAAAETAQND-DHDADDEDDG-HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR 1360
Query: 386 LSIFDANESGFESYEALPQHKLTCFS 411
I D E+ +S E P H + S
Sbjct: 1361 EKIKDKEETELDSEEEQPSHDTSVVS 1386
Score = 42.7 bits (99), Expect = 0.003
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 16/186 (8%)
Query: 108 ENGNQARSEARRVGMA-DANSPPKPLSKPRTPRRSKSDGEAKPE---PSPSPRITRKSTR 163
E QA +E G DA S P + P S +PE PR++ + R
Sbjct: 1226 EEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ-R 1284
Query: 164 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 223
Q+ + P +P+EE + A + D D ++ +++++ P E
Sbjct: 1285 QSEEEQQELEEP---EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
Query: 224 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR------EARAGVQADEDED 277
+ + G + + +K ++++ KE T +E+P E AG + D +ED
Sbjct: 1342 KEEPGVQESFLDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 278 GDEKDE 283
K+E
Sbjct: 1400 SHTKEE 1405
Score = 32.0 bits (71), Expect = 5.0
Identities = 76/344 (22%), Positives = 129/344 (37%), Gaps = 57/344 (16%)
Query: 38 EKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSE-----EGYLAKVKSLLNKDLS- 91
+ E +E+ E L + D + L K LSE G L K L L+
Sbjct: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTE 964
Query: 92 -LENGAHAYNREVNGRLENGNQARSEARRVGMADANSPP---KPLSKPRTPRRSKSDGEA 147
E Y+ L +++ E ++SPP KP K + P +
Sbjct: 965 GSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVR 1024
Query: 148 KPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRV 207
K + S +T + T + + +P R + I EE++++DE +
Sbjct: 1025 KRKHHNSSVVTETISETTEVLDEPFEDSDSERPMP---RLEPTFEIDEEEEEEDENE--L 1079
Query: 208 TSRERVARPLPAEEPERAKSGT-RTEKEEERDEKEE----------------KRLRSQTK 250
RE R L +++ R +S + R K+EE DE+ + + +++
Sbjct: 1080 FPREYFRR-LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPL 1138
Query: 251 EP---TPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR----------------SQPK 291
EP TP +K K P ++R + + G + K R S PK
Sbjct: 1139 EPDTSTPLKKKKGWPKGKSRKPIHW-KKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPK 1197
Query: 292 DLAAKRRPEEKEPEK-VNPQISDEKDEDEKEEKRRKTTPKEPTE 334
A R+P+ +E E+ V P+ E+ KEE+ + +E E
Sbjct: 1198 ---AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEE 1238
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.5 bits (158), Expect = 4e-10
Identities = 60/222 (27%), Positives = 103/222 (46%), Gaps = 14/222 (6%)
Query: 128 PPKPLSKPRTPRRSKSDGEAKP-EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 186
PPK L++ P D +A P P P P S +Q K +R+ E S
Sbjct: 409 PPKLLAQQHPP----PDRQAVPGRPGPFP-----SKQQVADEDEIWK-QRRRQQSEISAA 458
Query: 187 AKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR 246
+ +EE++ + E++R+ E++ R L + K + E E EKE +R +
Sbjct: 459 VERARKRREEEERRMEEQRKAACAEKLKR-LDEKLGILEKQPSPEEIREREREKEREREK 517
Query: 247 SQTKEPTPKQKLKEEPDREARAGVQAD-EDEDGDEKDEKKHRSQPKDLAAKRRPE-EKEP 304
KE +++ + E DRE + + + E E +++ +K R Q K+ +R+ E EKE
Sbjct: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKEL 577
Query: 305 EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNS 346
+K+ Q + + E E+E+ K P+EP + M + NS
Sbjct: 578 QKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENS 619
Score = 46.2 bits (108), Expect = 3e-04
Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 35/255 (13%)
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEES 184
+NSP + S+ + + S+++ K S KS+ Q AK P + P
Sbjct: 342 SNSPKENNSEDQGSKASENNENKKETDEVS---NTKSSSQIPAQPSVAKVPYGKGPSFNQ 398
Query: 185 ERAKSDESIKEEDKDQDEKRRRVTSRERVARPLP-------AEEPERAKSGTRTEKE--- 234
ER S + K ++ + RP P A+E E K R + E
Sbjct: 399 ERGTSSH-LPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISA 457
Query: 235 -----EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 289
+R E+EE+R+ Q K +KLK ++ Q +E E++ +K R +
Sbjct: 458 AVERARKRREEEERRMEEQRKAACA-EKLKRLDEKLGILEKQPSPEEIR-EREREKERER 515
Query: 290 PKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE-----------EKRRKTTPKEPTEKKMA 338
K+L + +E+E EK + + + E EKE EK RK ++ E++
Sbjct: 516 EKEL---EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKE 572
Query: 339 RAKTVMNSKTHPPKC 353
+ K + K +C
Sbjct: 573 KEKELQKMKEQEKEC 587
Score = 45.8 bits (107), Expect = 3e-04
Identities = 38/175 (21%), Positives = 72/175 (41%), Gaps = 14/175 (8%)
Query: 150 EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS 209
E PSP R+ R+ +R+ ++E E+ + E KE +KD++ ++ +
Sbjct: 496 EKQPSPEEIREREREK-----------EREREKELEKEQEQEREKEREKDRERQQEKEKE 544
Query: 210 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAG 269
E+ E ER + EKE ER +++EK L+ ++ + KE E +
Sbjct: 545 LEKEQEKQREMEKERKQE---KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601
Query: 270 VQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 324
+ E EK E ++ ++ R + EK + E + + + R
Sbjct: 602 PREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656
Score = 45.1 bits (105), Expect = 6e-04
Identities = 48/211 (22%), Positives = 93/211 (44%), Gaps = 26/211 (12%)
Query: 139 RRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDK 198
R+ + + E + E K R K P+ + +E ER K E KE +K
Sbjct: 463 RKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRER-EREKEREREKELEK 521
Query: 199 DQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD-EKE-----EKRLRSQTKEP 252
+Q+++R + ++R + +E E+ E+E++R+ EKE EK L Q ++
Sbjct: 522 EQEQEREKEREKDRERQQEKEKELEK-------EQEKQREMEKERKQEKEKELERQKEKE 574
Query: 253 TPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP--KDLAAKRRPE---EKEPEKV 307
QK+KE+ + + +++ ++ +EK +P + + K+ E KE E V
Sbjct: 575 KELQKMKEQEK-------ECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
Query: 308 NPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
+ + E E +T P+ ++ + A
Sbjct: 628 FTRQDSNRSEKEATPVVHETEPESGSQPRPA 658
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/257 (19%), Positives = 104/257 (40%), Gaps = 30/257 (11%)
Query: 102 EVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKS 161
E++ +E + R E R K + R + G + +PSP R+
Sbjct: 454 EISAAVERARKRREEEER----RMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
Query: 162 TRQTTITSHFAKGPAKRKPQE-ESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 220
++ K + + +E E +R + E KE +K+Q EK+R + + + E
Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ-EKQREMEKERKQEKEKELE 568
Query: 221 EPERAKSGTRTEKEEERD---EKEEKRL------RSQTKEPTPKQKLKEEPDREARAGVQ 271
+ + + KE+E++ EKE ++L R EP +++ E + V
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVF 628
Query: 272 ADEDEDGDEKD--------EKKHRSQPKDLAAK---RRPEEKEPEKVNPQISDEKDEDEK 320
+D + EK+ E + SQP+ ++ ++ P + Q K + +
Sbjct: 629 TRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQ 688
Query: 321 EEKRR----KTTPKEPT 333
+++++ +T P +P+
Sbjct: 689 QQQQQGVLPQTVPSQPS 705
Score = 34.7 bits (78), Expect = 0.77
Identities = 56/279 (20%), Positives = 96/279 (34%), Gaps = 51/279 (18%)
Query: 108 ENGNQARSEARRVGMADANSPPK-------PLSKPRTPRRSKSDGEAKPEPSPSPRITRK 160
E+G R + + +A PPK +PR R ++ + KP R
Sbjct: 1386 EDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREA 1445
Query: 161 STRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 220
+++ + + G QE K D + E
Sbjct: 1446 ASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQAN-----------E 1494
Query: 221 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPT------PKQKLKEEP-------DREAR 267
E E A + + ERDEK+ L +QT PK+++ + DR+ R
Sbjct: 1495 EWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNR 1554
Query: 268 AGVQADEDEDGD-EKDEKKHRSQPKDLAAKRRPEEKEP------EKVN----------PQ 310
G + + RS P + KR P + +P + +N P
Sbjct: 1555 RGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPN 1614
Query: 311 ISDEKDEDEKEEKRR---KTTPKEPTEKKMARAKTVMNS 346
+ +K+ + K+R K PK+P EK A ++ +N+
Sbjct: 1615 GTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNN 1653
Score = 32.7 bits (73), Expect = 2.9
Identities = 43/200 (21%), Positives = 74/200 (37%), Gaps = 20/200 (10%)
Query: 138 PRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEED 197
P + ++ ++ +P + T + ++ I++ ++ KR S + + + E
Sbjct: 884 PHHTDANNQSACFEAPDQK-TLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEP 942
Query: 198 KDQDEK--RRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPK 255
K R + S+E + RP E + K G E + EK K P P
Sbjct: 943 SAGIPKVTSRCIDSKEPIERP----EEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPS 998
Query: 256 QKLKEEP-DREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDE 314
+EE DR R + D K+E++ R +EKE EK
Sbjct: 999 SNRREEVNDRPVRRSGPIKKPVLRDMKEEREQR------------KEKEGEKAEKVTEKV 1046
Query: 315 KDEDEKEEKRRKTTPKEPTE 334
+ EK EK+ P P +
Sbjct: 1047 VVKPEKTEKKDLPPPPPPPQ 1066
Score = 32.3 bits (72), Expect = 3.8
Identities = 45/253 (17%), Positives = 98/253 (38%), Gaps = 28/253 (11%)
Query: 127 SPPKPLSKPR---TPRRSKSDGEAKPEPS-PSPRITRK-STRQTTITSH----FAKGPAK 177
S P P ++P+ TP+ ++ + + E + +IT S + +H F + ++
Sbjct: 809 SDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSE 868
Query: 178 RKPQEESERAKSDESIKEEDKDQ--------DEKRRRVTSRERVA--RPLPAEEPERAKS 227
+ Q+ R+ D D + D+K ER++ P+ + +
Sbjct: 869 AQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHG 928
Query: 228 GTRTEKEEERDEKEEKRLRSQTKE----PTPKQKLKEEPDREARAGVQADEDEDGDEKDE 283
T+K +E+ + + T P ++ +E+P +E + K +
Sbjct: 929 SNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSK 988
Query: 284 KKHRSQPKDLAAKR-----RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
+ R P+ + +R RP + P + D K+E E+ +++ ++ TEK +
Sbjct: 989 SETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVV 1048
Query: 339 RAKTVMNSKTHPP 351
+ + PP
Sbjct: 1049 KPEKTEKKDLPPP 1061
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 65.1 bits (157), Expect = 5e-10
Identities = 58/256 (22%), Positives = 121/256 (47%), Gaps = 16/256 (6%)
Query: 102 EVNGR-LENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS-DGEAKPEPSPSPRITR 159
EVNGR + RR + + S + S+ R R+S+S G +K S S +R
Sbjct: 164 EVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSR 223
Query: 160 KSTRQTTITSHFAKGPAK------RKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERV 213
+R + + ++ ++ R P +E R++S + K K +D+ ++ + + V
Sbjct: 224 SGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 214 ARPLPAEEPERAKSGTRTE-KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR-EARAGVQ 271
+P + P R KS +++ + +ER +EEKR S ++ + ++ L++ R ++ G +
Sbjct: 284 GKP-KSRSPSRHKSKSKSRSRSQERRVEEEKR-GSVSRGRSQEKSLRQSRSRSRSKGGSR 341
Query: 272 ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 331
+ KD++K R + ++ + R + E+ + ++D K++K KE
Sbjct: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR-GSKRDSKAGSSKKKK---KE 397
Query: 332 PTEKKMARAKTVMNSK 347
T++ +R+ + SK
Sbjct: 398 DTDRSQSRSPSRSVSK 413
Score = 60.1 bits (144), Expect = 2e-08
Identities = 55/272 (20%), Positives = 115/272 (42%), Gaps = 17/272 (6%)
Query: 88 KDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPR-RSKSDGE 146
K S + + + + R +G+++RS++R + + S + P + RS+S
Sbjct: 203 KSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA 262
Query: 147 AKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRR 206
K + K + ++ P++ K + +S R++S E EE+K R R
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS-RSRSQERRVEEEKRGSVSRGR 321
Query: 207 VTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPT-PKQKLKEEPDRE 265
S+E+ R + R+K G+R+ K++++ R +++E + + + + + +R
Sbjct: 322 --SQEKSLRQ--SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
Query: 266 ARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE---- 321
+ G + D + G K +KK + + R KE E + S + E E
Sbjct: 378 RKRGSKRD-SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
Query: 322 -----EKRRKTTPKEPTEKKMARAKTVMNSKT 348
+ R + +P +R+++ SKT
Sbjct: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Score = 41.6 bits (96), Expect = 0.006
Identities = 41/189 (21%), Positives = 86/189 (45%), Gaps = 15/189 (7%)
Query: 69 RKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSP 128
R+ E + G +++ +S ++ SL + R + ++++S+ +R G +
Sbjct: 307 RRVEEEKRGSVSRGRS---QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE 363
Query: 129 PKPLSKPRTP-RRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERA 187
+ S+ R+ RS+ G + + S ++K ++ T S ++ P+ R +E E A
Sbjct: 364 SRSRSRSRSKSERSRKRGSKRDSKAGS---SKKKKKEDTDRSQ-SRSPS-RSVSKEREHA 418
Query: 188 KSDESIKEEDKDQD------EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 241
KS+ S +E + + E R R S + LP+E R+KS ++T + +
Sbjct: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
Query: 242 EKRLRSQTK 250
R S+++
Sbjct: 479 ASRSPSRSR 487
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 65.1 bits (157), Expect = 5e-10
Identities = 71/340 (20%), Positives = 133/340 (39%), Gaps = 56/340 (16%)
Query: 69 RKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSP 128
+KE+ +E K KS L ++ SL+ + + R SE A +SP
Sbjct: 414 KKEKKDKERENEKEKSALARERSLKK---RQSLPASPRARLSASTASELSPKSKARPSSP 470
Query: 129 PKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAK-GPAKRKPQEESERA 187
+P +P S G P PSPR T S + AK P+ P+++S+
Sbjct: 471 STSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSK 530
Query: 188 KSDESIKEE-------------------DKDQDEKRRRVTSRERVARPLPAE--EPERAK 226
+ + KE K+Q + + P PA P +
Sbjct: 531 RRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPM 590
Query: 227 SGT--------------RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQA 272
+GT R +E+ E++E+RL+++ + +++L E + A +A
Sbjct: 591 AGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEA 650
Query: 273 DEDEDGD-------EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR- 324
E+ + E++E++ + K+ A R EE E +++ + ++ E E++E+R
Sbjct: 651 RRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRK 710
Query: 325 ---------RKTTPKEPTEKKMARAKTVMNSKTHPPKCIQ 355
RK+ E +K+ ++ S P K ++
Sbjct: 711 RLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVE 750
Score = 61.6 bits (148), Expect = 6e-09
Identities = 57/252 (22%), Positives = 103/252 (40%), Gaps = 25/252 (9%)
Query: 110 GNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRIT----------- 158
G R E + + A K SK R +S A P PSP+P T
Sbjct: 506 GRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPA 565
Query: 159 RKSTRQTTITSHFAKGP--------AKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSR 210
T +TS A P A +EE+ R +++ + ++ + E++ R
Sbjct: 566 ETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQA 625
Query: 211 ERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGV 270
ER R + A++ E E R E++E R ++Q ++ ++ K++ + EAR+
Sbjct: 626 ERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSRE 685
Query: 271 QADEDEDGDEKDEKKHRSQPKDLAAKRRP--EEKEPEKVNPQISDEKDEDEKEEKRRKTT 328
+A+ + +KH Q + +RR EE ++S+ K + + +E +
Sbjct: 686 EAERQR----LEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGS 741
Query: 329 PKEPTEKKMARA 340
EP + AR+
Sbjct: 742 SPEPVKAVEARS 753
Score = 53.5 bits (127), Expect = 2e-06
Identities = 56/248 (22%), Positives = 99/248 (39%), Gaps = 44/248 (17%)
Query: 108 ENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPE-------PSPSPRIT-- 158
++ +A +E A P P P P++ + E + P+P+P +T
Sbjct: 528 QSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPS 587
Query: 159 ---------RKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD-------- 201
++TR A+ +R+ QE +A+ D+ ++EE ++
Sbjct: 588 KPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAERE 647
Query: 202 -EKRRRVTSRERVARPLPAEEPER-------AKSGTRTEKEEERDEKEEKRLRSQTKEPT 253
E RRR R EE ER A++ +R E E +R E+E K + Q +E
Sbjct: 648 AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLERE-KHFQQQEQERQ 706
Query: 254 PKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAA---------KRRPEEKEP 304
++K EE + R ++ + D K+ + S P+ + A K +++EP
Sbjct: 707 ERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEP 766
Query: 305 EKVNPQIS 312
PQ S
Sbjct: 767 IPQEPQWS 774
Score = 42.4 bits (98), Expect = 0.004
Identities = 46/187 (24%), Positives = 75/187 (40%), Gaps = 38/187 (20%)
Query: 116 EARRVGMADANSPPKPLSK------PRTPRRSKS--------------DGEAKPEPSPSP 155
E R D + PP P+S P TP K+ G+ P P+P
Sbjct: 24 EPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQ 83
Query: 156 RITRKSTRQTTITSHFAKGPAKRKPQEESER-------AKSDESIKEEDKDQDEKRRRVT 208
+ S ++ + A GP +P S + A K+E K E+ +
Sbjct: 84 EESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAK 143
Query: 209 SR-ERVARPLPA------EEPERAKSGTRTEKEEERDEKEEKRLRSQTK----EPTPKQK 257
R E A+ L A E+ E+AK+ + +E R EE+RL+++ + E +QK
Sbjct: 144 ERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQK 203
Query: 258 LKEEPDR 264
L++ +R
Sbjct: 204 LEKNKER 210
Score = 37.4 bits (85), Expect = 0.12
Identities = 52/243 (21%), Positives = 88/243 (36%), Gaps = 30/243 (12%)
Query: 107 LENGNQARSEARRVGMADANSPPKPLSKPR------TPRRSKSDGEAKPEPSPSPRITRK 160
+E+G +A A A +PP+P P P S + P+ P+ +
Sbjct: 1 MESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMK-NAT 59
Query: 161 STRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 220
S++Q + G +P E + S E+ R R ++P P
Sbjct: 60 SSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTA 119
Query: 221 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDE 280
P T+ E K+ + KL +E RE RA A + E
Sbjct: 120 VPASDSPPTKQE----------------VKKAGERHKLAKER-REERAKYLAAKKAVWLE 162
Query: 281 KDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARA 340
K+EK + K L +RR E++ ++ E+ EE++R+ K + A
Sbjct: 163 KEEKAKALREKQLQERRRRLEEQ------RLKAEQRRAALEERQRQKLEKNKERYEAAIQ 216
Query: 341 KTV 343
++V
Sbjct: 217 RSV 219
Score = 31.6 bits (70), Expect = 6.5
Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 20/140 (14%)
Query: 123 ADANSPPKPLSKPRT---PRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRK 179
A + P P PR PRRS ++P P+ P T+Q + AK +
Sbjct: 91 AKSRGPTPPAMGPRDARPPRRS-----SQPSPTAVPASDSPPTKQEVKKAGERHKLAKER 145
Query: 180 PQEESE--RAKSDESIKEEDK------DQDEKRRRVTSRERVARPLPAEEPERAKSGTRT 231
+E ++ AK +++E+K Q ++RRR +R L AE+ A +
Sbjct: 146 REERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQR----LKAEQRRAALEERQR 201
Query: 232 EKEEERDEKEEKRLRSQTKE 251
+K E+ E+ E ++ K+
Sbjct: 202 QKLEKNKERYEAAIQRSVKK 221
Score = 31.6 bits (70), Expect = 6.5
Identities = 25/142 (17%), Positives = 65/142 (45%), Gaps = 11/142 (7%)
Query: 140 RSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAK--SDESIKEED 197
R++ + EA+ R ++ ++ K A+ + +EE+ER + ++ ++++
Sbjct: 643 RAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQE 702
Query: 198 KDQDEKRRRV------TSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRS---Q 248
+++ E+R+R+ T + V+ ++ + A + + + + E L+ Q
Sbjct: 703 QERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQ 762
Query: 249 TKEPTPKQKLKEEPDREARAGV 270
+EP P++ P +E A +
Sbjct: 763 KEEPIPQEPQWSLPSKELPASL 784
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 64.7 bits (156), Expect = 7e-10
Identities = 63/270 (23%), Positives = 114/270 (42%), Gaps = 32/270 (11%)
Query: 68 LRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANS 127
+ KE+++ + L+++++S H E G+ E Q + RR
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERR-------- 310
Query: 128 PPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERA 187
+ R R + + E + E R+ R+ +++ + E ER
Sbjct: 311 ---ERERERERERERRERERERE--------REREREK-----------EKERERERERD 348
Query: 188 KSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRS 247
+ + KE D+D+D +R R RER + R KS R + E E+E +R R
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 248 QTKEPTPKQKLKEEPDREARAGVQADED-EDGDEKDEKKHRSQPKDLAAKRRPEEKEPEK 306
+ +E +++ + E +RE +ED ED E+ + + + + K+ A + R + E +
Sbjct: 409 REREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRE 468
Query: 307 VNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
EK E E+EE+RR+ KE K
Sbjct: 469 RKKTREYEK-EAEREEERRREMAKEAKRLK 497
Score = 62.8 bits (151), Expect = 3e-09
Identities = 72/364 (19%), Positives = 139/364 (38%), Gaps = 38/364 (10%)
Query: 11 PTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRK 70
P + P I+ D +++ +RD ++ + + +F T K + E K +K
Sbjct: 252 PLIPYPLITKEDINAIEMEEDKRDLISRE---------ISKFRDTHKKLE----EEKGKK 298
Query: 71 EELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADAN-SPP 129
E+ +E + K + ++ E RE E + E R D + +
Sbjct: 299 EKERQE--IEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKE 356
Query: 130 KPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKS 189
+ + R R + + R KS + + +R+ + E ER +
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE 416
Query: 190 DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQT 249
E +E ++++D+KR R E E R K E+ + + +E K+ R
Sbjct: 417 REREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYE 476
Query: 250 KEPTPKQKLKEEPDREARAGVQADEDEDGDEKD---------EKKHRSQPKDLAAKRRPE 300
KE +++ + E +EA+ + ED D D D +K+ R + K++ A R
Sbjct: 477 KEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDR 536
Query: 301 EKEPEKV-------------NPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSK 347
++E E++ +P ++ E E E +R+ +EP ++ K K
Sbjct: 537 KREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEK 596
Query: 348 THPP 351
P
Sbjct: 597 REEP 600
Score = 49.3 bits (116), Expect = 3e-05
Identities = 43/180 (23%), Positives = 83/180 (46%), Gaps = 24/180 (13%)
Query: 179 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER-----------AKS 227
K E ER K+ E KE +++++ +R +R+ L + +R K
Sbjct: 462 KNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKR 521
Query: 228 GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR 287
EKE E DE++ KR + + +E + + PD +A E + E + R
Sbjct: 522 LRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA---------ELQRMEQEAERR 572
Query: 288 SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTP-KEPTEKKMARAKTVMNS 346
QP+ K+ PE +E E+ + ++++E +EE+ + P +PT + ++ A +V ++
Sbjct: 573 RQPQ---IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSA 629
Score = 47.8 bits (112), Expect = 9e-05
Identities = 72/360 (20%), Positives = 123/360 (34%), Gaps = 64/360 (17%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R R ++ ER+ E+E +EK E + LE KLR++E + + +
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ------ER 460
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV-----GMADANSPPKPLSKPRTPR 139
L N ++ Y +E E + EA+R+ D PK +
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 140 RSKSDGEAKPEPSPSPRITRKST----RQTTITSHFAKGPAKRKPQEESERAKSDESIKE 195
R + D E + E R K RQ + A+ + E+ + IK+
Sbjct: 521 RLR-DREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQ 579
Query: 196 EDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPK 255
E + ++E EE ++ K R E EE +E E+K T P
Sbjct: 580 EPESEEE-----------------EEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISS 622
Query: 256 ---------QKLKEEPDREARAGVQADEDEDGDEKDEKKHR---------------SQPK 291
P E+ G+ + D++ ++HR QP
Sbjct: 623 APSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPN 682
Query: 292 DLAAKRRPEEKEPEKVNPQISDEKDEDEK-------EEKRRKTTPKEPTEKKMARAKTVM 344
+ K+ P + K + SD+ K E+ + T TE+K K+++
Sbjct: 683 SVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNATKGTVNTEEKRKHIKSLI 742
Score = 40.0 bits (92), Expect = 0.018
Identities = 34/169 (20%), Positives = 77/169 (45%), Gaps = 6/169 (3%)
Query: 176 AKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSR---ERVARPLPAEEPERAKSGTRTE 232
AK+K + R ++ + EE D++ KRR + E + R +E ++
Sbjct: 174 AKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHP 233
Query: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 292
+++++++KE+ R P + +E + A ++ D ++ K R K
Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKE---DINAIEMEEDKRDLISREISKFRDTHKK 290
Query: 293 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341
L ++ +EKE +++ + + + E E+E +RR+ + E++ + K
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 64.3 bits (155), Expect = 9e-10
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 20/171 (11%)
Query: 149 PEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT 208
P+P P P + I FA P +EESE DE ED+DQ+ +R R+
Sbjct: 314 PKPIPLPGVRN-------IIFPFAPSPN----EEESE----DEEYYSEDEDQEARRHRLH 358
Query: 209 SRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQT--KEPTPKQKLKEEPDREA 266
S+++ R ++ + K +KEEE +KEEK + K+ +++++ + + E
Sbjct: 359 SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEG 418
Query: 267 RAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 317
+ + DEDEDG +K E + + P + E E E ++ D+ DE
Sbjct: 419 ESKDEEDEDEDGGQKPEGEPQQDP---GTEETYGEVEEEPLDEAQDDDLDE 466
Score = 41.2 bits (95), Expect = 0.008
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 24/143 (16%)
Query: 207 VTSRERVARPLPAEEPER-----AKSGTRTEKEEER-----DEKEEKRLRSQTKEPTPK- 255
+ + RV +P+P A S E E+E +++E +R R +K+ +
Sbjct: 307 IERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRM 366
Query: 256 ----QKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 311
Q++KE+ + E + + + E+ +E++E++ K++ EE+E N +
Sbjct: 367 RAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE---------MKQKEEEEEIRNKNEEE 417
Query: 312 SDEKDEDEKEEKRRKTTPKEPTE 334
+ KDE++++E + EP +
Sbjct: 418 GESKDEEDEDEDGGQKPEGEPQQ 440
Score = 35.8 bits (81), Expect = 0.35
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 22/140 (15%)
Query: 252 PTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP-----EEKEPEK 306
P+P ++ E+ + + EDED ++ ++HR KD + R +EKE E+
Sbjct: 331 PSPNEEESEDEEYYS-------EDED---QEARRHRLHSKDQRKRMRAFQQEMKEKEEEE 380
Query: 307 VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLD----- 361
+ + +K E+++EE+ + KE E+ + + SK + GQ +
Sbjct: 381 MKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
Query: 362 DPDLK--YGQHPPDAVDEPQ 379
DP + YG+ + +DE Q
Sbjct: 441 DPGTEETYGEVEEEPLDEAQ 460
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 63.5 bits (153), Expect = 2e-09
Identities = 68/309 (22%), Positives = 120/309 (38%), Gaps = 27/309 (8%)
Query: 45 KLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVN 104
KL + H+F++ I+ ETK+ E+ E L + L + E A +E
Sbjct: 445 KLKVQHKFVEEIIE------ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE-- 496
Query: 105 GRLENGNQARSEARRVGMADANSPPKPLS-KPRTPRRSKSDGEAKPEPSPSPRITRKSTR 163
EA +A SP K + + + K + E + E +
Sbjct: 497 --------EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 164 QTTITSHFAKGPAKRKPQEESE---RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 220
+ + + QEE E A+ +E+ +E+K +EK V ++E + E
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE 608
Query: 221 EPERAKSGTRTEKEEERDEK--EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDG 278
+PE+AKS EE+ + + + + K P PK ++E+ ++ +E G
Sbjct: 609 KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV---PKSPVEEKG 665
Query: 279 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
K + + P E+ K ++K+E+EKE K + +E EKK
Sbjct: 666 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK--EAPKEEKVEKKEE 723
Query: 339 RAKTVMNSK 347
+ K V K
Sbjct: 724 KPKDVPEKK 732
Score = 62.4 bits (150), Expect = 3e-09
Identities = 83/334 (24%), Positives = 148/334 (44%), Gaps = 47/334 (14%)
Query: 23 DVRRRL--KDLERDSLT-EKECVKEKLNLLHEFLQTEI---KNQLCDLETKLRKEELSEE 76
+ RR+L K +E +S+ KE ++ +L+ + E ++ ++ + LE +LR +
Sbjct: 319 EYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMA 378
Query: 77 GYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPR 136
+L + + LLN ++L+ AY + L G + R A S PL R
Sbjct: 379 RHLREYQDLLNVKMALDIEIAAYRK-----LLEGEETRFSTF------AGSITGPLYTHR 427
Query: 137 TPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE---SI 193
P S + +P ++ K + + K ++ EE+ A ++E S+
Sbjct: 428 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEET---KVEDEKSEMEEALTAITEELAVSM 484
Query: 194 KEEDKDQDEKRRRV--TSRERVAR---PLPAEEPE-RAKSGTRTEKE-EERDEKEEKRLR 246
KEE K+ E++ E VA P+ A PE + + G + E+E +E +E+E++ +
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 247 SQTKEPTPKQKL----KEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEK 302
S E +K KEE ++E E E+ + K+EKK + +++A K
Sbjct: 545 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE---- 600
Query: 303 EPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
++D K E K EK + PK P E+K
Sbjct: 601 -------LVADAKVE--KPEKAKSPVPKSPVEEK 625
Score = 51.6 bits (122), Expect = 6e-06
Identities = 69/324 (21%), Positives = 124/324 (38%), Gaps = 28/324 (8%)
Query: 17 AISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE---- 72
A+S+ ++ + ++ E + E+E V K + + + E+K + + E + +EE
Sbjct: 481 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQEEEEEE 539
Query: 73 -------LSEEGYLAKVKSLLNKDLSLENG---AHAYNREVNGRLENGNQARSE---ARR 119
+EEG K S ++ E G A A E + E + +SE +
Sbjct: 540 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599
Query: 120 VGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRK 179
+ADA +K P+ + P P KS + K P +
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 659
Query: 180 PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
P EE ++ +S EE + V + A E+ E + + +EE+ E
Sbjct: 660 PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVE 719
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
K+E++ + P++K E P +E +A + K K H + K
Sbjct: 720 KKEEK-----PKDVPEKKKAESPVKE-----EAVAEVVTITKSVKVHLEKETKEEGKPLQ 769
Query: 300 EEKEPEKVNPQISDEKDEDEKEEK 323
+EKE EK + E++ +K K
Sbjct: 770 QEKEKEKAGGEGGSEEEGSDKGAK 793
Score = 44.3 bits (103), Expect = 0.001
Identities = 82/371 (22%), Positives = 137/371 (36%), Gaps = 61/371 (16%)
Query: 30 DLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRK--EELSEEGYLAKVKSLLN 87
D + +EKE EK E +TE + + + E K K EE SEE K L
Sbjct: 546 DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE---VATKEELV 602
Query: 88 KDLSLENGAHAYNREVNGRLENGNQA---RSEARRVGMADANSPP------KPLSKPRTP 138
D +E A + +E ++ +S G + P P+ K
Sbjct: 603 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 662
Query: 139 RRSKSDGEAKP--EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIK-- 194
+ KS P E + SP + + + + KG K + ++E + A +E ++
Sbjct: 663 EKGKSPVSKSPVEEKAKSP-VPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 721
Query: 195 -EEDKDQDEKRRRVT--SRERVA---------------------RPLPAEEPERAKSGTR 230
E+ KD EK++ + E VA +PL +E E+ K+G
Sbjct: 722 EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQ-QEKEKEKAGGE 780
Query: 231 TEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDG--------DEKD 282
EEE +K K R + + + KEE ++E + E+E G D
Sbjct: 781 GGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPAD 840
Query: 283 EKKHRSQPKDLAAKRRPEEKEPEK----VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
EKK + ++ + EK + I+ +K E+ +T E+K+
Sbjct: 841 EKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEET-----FEEKLV 895
Query: 339 RAKTVMNSKTH 349
K V +H
Sbjct: 896 STKKVEKVTSH 906
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 63.5 bits (153), Expect = 2e-09
Identities = 68/309 (22%), Positives = 120/309 (38%), Gaps = 27/309 (8%)
Query: 45 KLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVN 104
KL + H+F++ I+ ETK+ E+ E L + L + E A +E
Sbjct: 69 KLKVQHKFVEEIIE------ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE-- 120
Query: 105 GRLENGNQARSEARRVGMADANSPPKPLS-KPRTPRRSKSDGEAKPEPSPSPRITRKSTR 163
EA +A SP K + + + K + E + E +
Sbjct: 121 --------EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 164 QTTITSHFAKGPAKRKPQEESE---RAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 220
+ + + QEE E A+ +E+ +E+K +EK V ++E + E
Sbjct: 173 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE 232
Query: 221 EPERAKSGTRTEKEEERDEK--EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDG 278
+PE+AKS EE+ + + + + K P PK ++E+ ++ +E G
Sbjct: 233 KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV---PKSPVEEKG 289
Query: 279 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
K + + P E+ K ++K+E+EKE K + +E EKK
Sbjct: 290 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK--EAPKEEKVEKKEE 347
Query: 339 RAKTVMNSK 347
+ K V K
Sbjct: 348 KPKDVPEKK 356
Score = 60.5 bits (145), Expect = 1e-08
Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 6/180 (3%)
Query: 178 RKPQEESERAKSD----ESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 233
+KP+ E+ + K E I EE K +DEK + + L E K ++
Sbjct: 61 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 120
Query: 234 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED-GDEKDEKKHRSQPKD 292
EE E+EE + + T + +EE ++E G + +E+ED G + D+ + K+
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 180
Query: 293 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPT-EKKMARAKTVMNSKTHPP 351
++++ E+E + + E+ E ++E+K + + + T E+ +A AK K P
Sbjct: 181 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 240
Score = 51.6 bits (122), Expect = 6e-06
Identities = 69/324 (21%), Positives = 124/324 (38%), Gaps = 28/324 (8%)
Query: 17 AISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE---- 72
A+S+ ++ + ++ E + E+E V K + + + E+K + + E + +EE
Sbjct: 105 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQEEEEEE 163
Query: 73 -------LSEEGYLAKVKSLLNKDLSLENG---AHAYNREVNGRLENGNQARSE---ARR 119
+EEG K S ++ E G A A E + E + +SE +
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223
Query: 120 VGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRK 179
+ADA +K P+ + P P KS + K P +
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 283
Query: 180 PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE 239
P EE ++ +S EE + V + A E+ E + + +EE+ E
Sbjct: 284 PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVE 343
Query: 240 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
K+E++ + P++K E P +E +A + K K H + K
Sbjct: 344 KKEEK-----PKDVPEKKKAESPVKE-----EAVAEVVTITKSVKVHLEKETKEEGKPLQ 393
Query: 300 EEKEPEKVNPQISDEKDEDEKEEK 323
+EKE EK + E++ +K K
Sbjct: 394 QEKEKEKAGGEGGSEEEGSDKGAK 417
Score = 44.3 bits (103), Expect = 0.001
Identities = 82/371 (22%), Positives = 137/371 (36%), Gaps = 61/371 (16%)
Query: 30 DLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRK--EELSEEGYLAKVKSLLN 87
D + +EKE EK E +TE + + + E K K EE SEE K L
Sbjct: 170 DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE---VATKEELV 226
Query: 88 KDLSLENGAHAYNREVNGRLENGNQA---RSEARRVGMADANSPP------KPLSKPRTP 138
D +E A + +E ++ +S G + P P+ K
Sbjct: 227 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 139 RRSKSDGEAKP--EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIK-- 194
+ KS P E + SP + + + + KG K + ++E + A +E ++
Sbjct: 287 EKGKSPVSKSPVEEKAKSP-VPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 345
Query: 195 -EEDKDQDEKRRRVT--SRERVA---------------------RPLPAEEPERAKSGTR 230
E+ KD EK++ + E VA +PL +E E+ K+G
Sbjct: 346 EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQ-QEKEKEKAGGE 404
Query: 231 TEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDG--------DEKD 282
EEE +K K R + + + KEE ++E + E+E G D
Sbjct: 405 GGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPAD 464
Query: 283 EKKHRSQPKDLAAKRRPEEKEPEK----VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 338
EKK + ++ + EK + I+ +K E+ +T E+K+
Sbjct: 465 EKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEET-----FEEKLV 519
Query: 339 RAKTVMNSKTH 349
K V +H
Sbjct: 520 STKKVEKVTSH 530
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 63.5 bits (153), Expect = 2e-09
Identities = 54/226 (23%), Positives = 101/226 (44%), Gaps = 24/226 (10%)
Query: 130 KPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHF-------AKGPAKRKP-- 180
+P K R S+S ++ +PS R+S ++ SH +K P +R+
Sbjct: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
Query: 181 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK 240
+E R++S +++ K+ EK+R T P R++S +R E R +
Sbjct: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTP------PKSYSTARRSRSASR----ERRRRR 347
Query: 241 EEKRLRSQTKEPTPKQKLKEEPD-REARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 299
RS K +PK+KL P R + + D+D++ + ++ S+ K K +
Sbjct: 348 SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
Query: 300 EEK--EPEKVNPQISDEKDEDEK--EEKRRKTTPKEPTEKKMARAK 341
E+ E +K Q++ + DE+E+ + ++ K K+P E + K
Sbjct: 408 RERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTK 453
Score = 61.6 bits (148), Expect = 6e-09
Identities = 69/256 (26%), Positives = 113/256 (44%), Gaps = 33/256 (12%)
Query: 91 SLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPE 150
SL + A +++ R + +++RS RR +S S+ R+ RRS S ++
Sbjct: 231 SLISAAIEPDKKEEKRRHSRSRSRSRRRRT----PSSSRHRRSRSRSRRRSHSKSRSR-R 285
Query: 151 PSPSPRITRKSTRQTTITSH-FAKGPAKRKPQEESERAKS---DESIKEEDKDQDEKRRR 206
S SPR R +R+ S +K K+K +E +R+K+ S + +RRR
Sbjct: 286 RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
Query: 207 VTSRERVARPLPAEEPERAKS---GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLK--EE 261
SR P P+R S R K+E++ +K+++R R + + T K+K +E
Sbjct: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE 405
Query: 262 PDREARAGVQA---------DEDEDG-DEKDEKKHRSQPKDLAAKRRPE---EK------ 302
DRE ++ DE+E G D + EKK +P + + + E EK
Sbjct: 406 KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSL 465
Query: 303 EPEKVNPQISDEKDED 318
KVN E+D D
Sbjct: 466 RESKVNGDDHHEEDMD 481
Score = 36.2 bits (82), Expect = 0.26
Identities = 38/186 (20%), Positives = 75/186 (40%), Gaps = 29/186 (15%)
Query: 176 AKRKPQEESERAKSDESIKE---EDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 232
+ ++ +E +R + +S+ E ++EKRR SR R R +S +R+
Sbjct: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR 274
Query: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 292
+ + R R ++K P ++ E R +R+ + D ++D++K RS
Sbjct: 275 RRSH----SKSRSRRRSKSPRRRRSHSRERGRRSRS---TSKTRDKKKEDKEKKRS---- 323
Query: 293 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK----TTPKEP--TEKKMARAKTVMNS 346
K P K + + +RR +PK+P ++K++R+ +
Sbjct: 324 ---------KTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
Query: 347 KTHPPK 352
K K
Sbjct: 375 KKEKKK 380
Score = 32.3 bits (72), Expect = 3.8
Identities = 25/124 (20%), Positives = 49/124 (39%), Gaps = 8/124 (6%)
Query: 250 KEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNP 309
K T ++++E R A + D+K+EK+ S+ + + +RR + +
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
Query: 310 QISDEKDEDEKEEKRRKTTPKEPTEKKMARA-KTVMNSKTHPPKCIQCGQYLDDPDLKYG 368
S + + +RR +P+ R ++ SKT K +D + K
Sbjct: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKK-------KEDKEKKRS 323
Query: 369 QHPP 372
+ PP
Sbjct: 324 KTPP 327
>gi|157266334 tubby like protein 1 [Homo sapiens]
Length = 542
Score = 63.5 bits (153), Expect = 2e-09
Identities = 67/283 (23%), Positives = 115/283 (40%), Gaps = 38/283 (13%)
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHF 171
Q + A+R+ +P P PR+ + +P PSP + Q T+ + F
Sbjct: 33 QRPAPAQRLRKKRTEAPESPCPTGSKPRKPGAGRTGRPREEPSPDPAQARAPQ-TVYARF 91
Query: 172 AKGP--AKRKPQEESERAKS----DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERA 225
+ P KR P+E A++ DE +EE+ ++DE+ +E++ LP ++P R
Sbjct: 92 LRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKIL--LPPKKPLRE 149
Query: 226 KSGTRTEKEEERDEKEEKRLRSQTKEPTP-KQKLKEEPDREA--------RAGVQADEDE 276
KS ++ + + L S P P + + KE P E + +AD+D
Sbjct: 150 KSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDP 209
Query: 277 DGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 336
G +K + L + P++K +K K+E+E+EE T K+ +K
Sbjct: 210 SGSPASARKSPA-AMFLVGEGSPDKKALKKKGTPKGARKEEEEEEE--AATVIKKSNQKG 266
Query: 337 MARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQ 379
A+ K +K + PP VDEP+
Sbjct: 267 KAKGKGKKKAKE-----------------ERAPSPPVEVDEPR 292
Score = 33.5 bits (75), Expect = 1.7
Identities = 37/161 (22%), Positives = 62/161 (38%), Gaps = 21/161 (13%)
Query: 128 PPKPLSKPRTP----RRSKSDGE----AKPEPSPSPRITRKSTRQTTITSHFAKGPAKRK 179
P KPL + + RR+K+ G P+P P P R +G RK
Sbjct: 143 PKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPA------GEGTKMRK 196
Query: 180 PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKS---GTRTEKEEE 236
+++ S E+ K+ R+ + V P ++ + K G R E+EEE
Sbjct: 197 TKKKG----SGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEE 252
Query: 237 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 277
+ + +Q + K K K + +R V+ DE +
Sbjct: 253 EEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPRE 293
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.8 bits (151), Expect = 3e-09
Identities = 79/362 (21%), Positives = 160/362 (44%), Gaps = 45/362 (12%)
Query: 30 DLERDSLTEKECVKEKLNLLHEFLQ------TEIKNQLCDLETKLRKEEL--------SE 75
+L R+++T++E +KEK L E LQ +EI+ + +L+ KL + +L +E
Sbjct: 196 ELYRNTITDEE-LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAE 254
Query: 76 EGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKP 135
+L K ++ L + + +N + E + E + + + +
Sbjct: 255 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ 314
Query: 136 RTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKE 195
R + + + E + ++ I K + K +E+ E+ + +E I+E
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 196 EDKDQDEK----RRRVTSRERVARPLPAEE---PERAKSGTRTEK----EEERDEKEEKR 244
++K Q+++ R+ RE+ + EE + K G + EK EEE E+EEK
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 245 LRSQTKEPTPKQKLKEEPD--REARAGVQADEDEDGD------------EKDEKKHRSQP 290
R + K ++K++E+ + RE +Q E++ G+ ++ E+K R Q
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Query: 291 KDLAAKRRPEEKEPEKVNPQISDEKDEDEK----EEKRRKTTPK-EPTEKKMARAKTVMN 345
+ + + + ++ EK+ Q ++++EK EEK + K + E+KM R + M
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 346 SK 347
+
Sbjct: 555 EQ 556
Score = 51.6 bits (122), Expect = 6e-06
Identities = 30/143 (20%), Positives = 70/143 (48%), Gaps = 2/143 (1%)
Query: 181 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK 240
++E + + +E I+E++K E+ ++ +E + + EE + G E+E + E+
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEEKMGEQEGKMCEQEAKMQEQ 486
Query: 241 EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE 300
EEK R + K ++K++E+ ++ E E+ + E+K Q + + +
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 301 EKEPEKVNPQISDEKDEDEKEEK 323
++ EK+ Q + ++EK ++
Sbjct: 547 RRQEEKMREQEVRLRQQEEKMQE 569
Score = 32.7 bits (73), Expect = 2.9
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Query: 176 AKRKPQEESERAKSDESIKEEDK---DQDEKRRRVTS--RERVARPLPAEEPERAKSGTR 230
AK + QEE R + +E I+E++K +Q+EK R +E+ + EE +
Sbjct: 481 AKMQEQEEKMR-RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Query: 231 TEKEEERDEKEEKRLRSQTKEPTPKQKLKE 260
E+EE+ +EEK + + ++K++E
Sbjct: 540 QEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 62.4 bits (150), Expect = 3e-09
Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 10/161 (6%)
Query: 141 SKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQ 200
S + PE P+P +Q + TS F R+ ++ + ++++ +DQ
Sbjct: 288 SSPSSTSSPEGPPAP------PKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQ 341
Query: 201 DEKRRRVTSR-ERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTK---EPTPKQ 256
+ +++ R ER + EE +RAK + +KEEE++ KE++R + K E KQ
Sbjct: 342 ERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQ 401
Query: 257 KLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR 297
+LKEE +E + ++A +E +++EK+ R + K + A++
Sbjct: 402 RLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
Score = 49.3 bits (116), Expect = 3e-05
Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 40/270 (14%)
Query: 128 PPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERA 187
PP+ S P TP+ +P + + ++ SH S +
Sbjct: 250 PPQIKSLPATPQGKNM--------TPESEVLESFPEEDSVLSH-------------SSLS 288
Query: 188 KSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRS 247
+ E K+ TS + PL + K T EK + R +++++RL
Sbjct: 289 SPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGST--EKNKLRLQRDQERLGK 346
Query: 248 QTK---EPTPKQKLKEEPDR---EARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEE 301
Q K E K+KLKEE R EA+ + +++ E+ EK+ + + + +R EE
Sbjct: 347 QLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEE 406
Query: 302 KEPEKVNPQISDEKDEDEKEEKRRKTTPK--EPTEKKMARAKTVMNSKTHPPKCIQCGQY 359
+ E+ E E + EEKR+K K EK++ K + PK Q +
Sbjct: 407 RRKER------QEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKT 460
Query: 360 LDDPDLKYGQHPPDAVDEPQMLTNEKLSIF 389
L G+ P + E +L + + F
Sbjct: 461 LAG---SCGKFAPFEIKEHMVLAPRRRTAF 487
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,682,667
Number of Sequences: 37866
Number of extensions: 3730352
Number of successful extensions: 44508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 495
Number of HSP's successfully gapped in prelim test: 1156
Number of HSP's that attempted gapping in prelim test: 19369
Number of HSP's gapped (non-prelim): 10969
length of query: 1616
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1500
effective length of database: 13,855,062
effective search space: 20782593000
effective search space used: 20782593000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.