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Search of human proteins with 4503257
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503257 death-domain associated protein isoform a [Homo
sapiens]
(740 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 1466 0.0
gi|215422388 death-domain associated protein isoform a [Homo sap... 1466 0.0
gi|215422366 death-domain associated protein isoform b [Homo sap... 1457 0.0
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 79 2e-14
gi|17975763 myelin transcription factor 1 [Homo sapiens] 75 2e-13
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 73 8e-13
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 68 3e-11
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 67 8e-11
gi|4505999 protein phosphatase 1G [Homo sapiens] 66 1e-10
gi|29826282 protein phosphatase 1G [Homo sapiens] 66 1e-10
gi|21735569 claspin [Homo sapiens] 64 5e-10
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 64 5e-10
gi|55956788 nucleolin [Homo sapiens] 63 9e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 63 1e-09
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 62 1e-09
gi|218505694 potassium channel tetramerisation domain containing... 62 1e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 62 1e-09
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 62 2e-09
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09
gi|115529449 upstream binding transcription factor, RNA polymera... 62 3e-09
gi|115529451 upstream binding transcription factor, RNA polymera... 62 3e-09
gi|7657671 upstream binding transcription factor, RNA polymerase... 62 3e-09
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 61 3e-09
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 61 3e-09
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 61 4e-09
gi|21361639 DIPB protein [Homo sapiens] 60 6e-09
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 1466 bits (3796), Expect = 0.0
Identities = 740/740 (100%), Positives = 740/740 (100%)
Query: 1 MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYK 60
MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYK
Sbjct: 1 MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYK 60
Query: 61 LENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRP 120
LENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRP
Sbjct: 61 LENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRP 120
Query: 121 AKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR 180
AKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR
Sbjct: 121 AKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR 180
Query: 181 TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLC 240
TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLC
Sbjct: 181 TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLC 240
Query: 241 ELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARH 300
ELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARH
Sbjct: 241 ELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARH 300
Query: 301 SLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARR 360
SLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARR
Sbjct: 301 SLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARR 360
Query: 361 LRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 420
LRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS
Sbjct: 361 LRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 420
Query: 421 GMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
GMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE
Sbjct: 421 GMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
Query: 481 DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAP 540
DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAP
Sbjct: 481 DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAP 540
Query: 541 SSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTV 600
SSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTV
Sbjct: 541 SSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTV 600
Query: 601 LENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNG 660
LENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNG
Sbjct: 601 LENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNG 660
Query: 661 KKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTC 720
KKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTC
Sbjct: 661 KKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTC 720
Query: 721 KTSVATQCDPEEIIVLSDSD 740
KTSVATQCDPEEIIVLSDSD
Sbjct: 721 KTSVATQCDPEEIIVLSDSD 740
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 1466 bits (3796), Expect = 0.0
Identities = 740/740 (100%), Positives = 740/740 (100%)
Query: 1 MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYK 60
MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYK
Sbjct: 1 MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYK 60
Query: 61 LENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRP 120
LENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRP
Sbjct: 61 LENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRP 120
Query: 121 AKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR 180
AKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR
Sbjct: 121 AKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR 180
Query: 181 TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLC 240
TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLC
Sbjct: 181 TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLC 240
Query: 241 ELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARH 300
ELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARH
Sbjct: 241 ELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARH 300
Query: 301 SLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARR 360
SLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARR
Sbjct: 301 SLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARR 360
Query: 361 LRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 420
LRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS
Sbjct: 361 LRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 420
Query: 421 GMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
GMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE
Sbjct: 421 GMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
Query: 481 DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAP 540
DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAP
Sbjct: 481 DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAP 540
Query: 541 SSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTV 600
SSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTV
Sbjct: 541 SSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTV 600
Query: 601 LENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNG 660
LENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNG
Sbjct: 601 LENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNG 660
Query: 661 KKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTC 720
KKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTC
Sbjct: 661 KKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTC 720
Query: 721 KTSVATQCDPEEIIVLSDSD 740
KTSVATQCDPEEIIVLSDSD
Sbjct: 721 KTSVATQCDPEEIIVLSDSD 740
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 1457 bits (3772), Expect = 0.0
Identities = 735/735 (100%), Positives = 735/735 (100%)
Query: 6 SIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEK 65
SIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEK
Sbjct: 18 SIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEK 77
Query: 66 LFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYV 125
LFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYV
Sbjct: 78 LFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYV 137
Query: 126 YINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSR 185
YINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSR
Sbjct: 138 YINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSR 197
Query: 186 RQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLCELKDC 245
RQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLCELKDC
Sbjct: 198 RQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLCELKDC 257
Query: 246 SSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARHSLGLP 305
SSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARHSLGLP
Sbjct: 258 SSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARHSLGLP 317
Query: 306 RQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENR 365
RQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENR
Sbjct: 318 RQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENR 377
Query: 366 SLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQ 425
SLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQ
Sbjct: 378 SLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQ 437
Query: 426 GCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEE 485
GCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEE
Sbjct: 438 GCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEE 497
Query: 486 AAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDA 545
AAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDA
Sbjct: 498 AAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDA 557
Query: 546 ESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGA 605
ESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGA
Sbjct: 558 ESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGA 617
Query: 606 GMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICT 665
GMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICT
Sbjct: 618 GMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICT 677
Query: 666 LPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVA 725
LPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVA
Sbjct: 678 LPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVA 737
Query: 726 TQCDPEEIIVLSDSD 740
TQCDPEEIIVLSDSD
Sbjct: 738 TQCDPEEIIVLSDSD 752
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 79.0 bits (193), Expect = 2e-14
Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%)
Query: 376 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 432
++K QDK + KR+ + +S D + + D E +
Sbjct: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
Query: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 492
+DE+DEE D EEEEE EEE+E+ D E+ ED+E +E +E++EEE+EEEE
Sbjct: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167
Query: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 549
+ + N + ++ ++ ++ E N +V+ SLL+ +A + ES
Sbjct: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225
Query: 550 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 609
+LE++S ++ + E L LD S V + S K +L G G+V
Sbjct: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276
Query: 610 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 664
S + N N+ DS + SR P+ N +E+ + E++ +++C
Sbjct: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 75.1 bits (183), Expect = 2e-13
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 12/108 (11%)
Query: 386 SEEGER------KKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDED 439
SEEGE+ + ++ T+ S D SL+ +G S +E+
Sbjct: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS------HEEE 260
Query: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
DEE +EEEEEEEE+EEEE + EEEE+ E+ +E +E++EEE+EEEEAA
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 40.0 bits (92), Expect = 0.008
Identities = 38/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 415 SGEGPSGMASQGCPSASRAETDDEDDEE---SDEEEEEEEEEEEEEATDSEEEEDLEQMQ 471
S EG G+ Q + E E ++ E+ EE +++ S EEED E+ +
Sbjct: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED-EEEE 265
Query: 472 EGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK-------QISRSSGEQQNK 524
E +E++EE++EEEE ++ ++ + E+ E + Q S Q
Sbjct: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
Query: 525 GRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE 570
+ P S +P ++ S+ ++ E+ T +S V+ E++
Sbjct: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDED-THSRKSTVTDESEMQ 370
Score = 39.7 bits (91), Expect = 0.010
Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 19/135 (14%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
+S E + ++ +G SH + E + E + E ++E++EE +
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Query: 445 EEEEEEEEE--------EEEEATDSEEEEDLEQMQEGQ-----------EDDEEEDEEEE 485
EEEEEEEEE E+ T +++ +L + D+++DE+
Sbjct: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357
Query: 486 AAAGKDGDKSPMSSL 500
+ D+S M +
Sbjct: 358 SRKSTVTDESEMQDM 372
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 10/103 (9%)
Query: 384 DKSEEGERKKRRARLQGTSSHSAD---TPEASLDSGEGPSGMASQGCPSASRAETDDEDD 440
D S RK+ A +S S+ +P+AS + +S P +S+A DE D
Sbjct: 670 DLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWD 729
Query: 441 EESD-------EEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 476
D EEE EE E + S E +D E +E E+
Sbjct: 730 RPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEE 772
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 73.2 bits (178), Expect = 8e-13
Identities = 69/240 (28%), Positives = 96/240 (40%), Gaps = 65/240 (27%)
Query: 419 PSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG----- 473
P G G P A + + SDEEEEEEEEEEEEE + EEEED E+ +E
Sbjct: 862 PEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYF 921
Query: 474 ---------------------QEDDEEEDEEEE-----------AAAGKDGDKS------ 495
+E++EEEDEEEE AG + ++
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT 981
Query: 496 -------PMSSLQISNEKNLEPGKQIS-RSSGEQQNKGRIVSPSLLSEEPLAPSSIDAES 547
P S ++ E EPG + G ++ +G +P+L E PS + E
Sbjct: 982 LPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE--ALPSQGEVER 1039
Query: 548 NGEQ------PEELTLEEESPVSQLFELEIE------ALPLDTPSSVETDISSSRKQSEE 595
GE P+EL EE S L E E E P +TP+ E + + + +E
Sbjct: 1040 EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQE 1099
Score = 32.7 bits (73), Expect = 1.2
Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 9/122 (7%)
Query: 381 MLQDKSEEGERKKRRARLQGTSSHSADTPEASLD-SGEGPS-GMASQGC----PSASRAE 434
+L + E G ++R A T + A + ++ GE P+ G Q PSA
Sbjct: 1005 LLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTL 1064
Query: 435 TDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDK 494
++E ++ SD+ + E EEE E E + E +QE ++DD + D +K
Sbjct: 1065 LEEETEDGSDKVQPPPETPAEEE---METETEAEALQEKEQDDTAAMLADFIDCPPDDEK 1121
Query: 495 SP 496
P
Sbjct: 1122 PP 1123
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 390 ERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEE 449
E +R +R +S ++ E D G SG + + + E E+D E DEE EE
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
Query: 450 EEEEEEEEATDSEEEEDLEQMQEGQEDDEEE----DEEEEAAAGKDGDKSPMSSLQISNE 505
+ EE+EE D EEEE+ E+ +E +E++EEE DE ++ G D D +S S
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
Query: 506 KNLEPGKQISRSSGE-------QQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEEL 555
+ G S S + ++ + R +SP + S +ES +Q +L
Sbjct: 278 VSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRS----GSSASESYADQTSKL 330
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/207 (21%), Positives = 83/207 (40%), Gaps = 31/207 (14%)
Query: 385 KSEEGERKKRRARLQG------TSSHSADT----PEASLDSGEGPSGMASQGCPS----- 429
K+EE +R +R RL +SS S + PE + P A P
Sbjct: 96 KNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERI 155
Query: 430 -------ASRAETDDEDDEESDEEEEEEE------EEEEEEATDSEEE---EDLEQMQEG 473
ASR+ +++ S+E + E +E+ T++EEE ED+E+ +E
Sbjct: 156 GLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEV 215
Query: 474 QEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLL 533
+ED EE++E +E ++ ++ + E+ E ++ + G + S S
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 534 SEEPLAPSSIDAESNGEQPEELTLEEE 560
S+ + S + +E E +
Sbjct: 276 ESVSFTDGSVRSGSGTDGSDEKKKERK 302
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 66.6 bits (161), Expect = 8e-11
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 11/152 (7%)
Query: 390 ERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEE 449
E +R +R +S ++ E D G SG + + + E E+D E DEE EE
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
Query: 450 EEEEEEEEATDSEEEEDLEQMQEGQEDDEEE----DEEEEAAAGKDGDKSPMSSLQISNE 505
+ EE+EE D EEEE+ E+ +E +E++EEE DE ++ G D D +S S
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
Query: 506 KNLEPGKQISRSSGE-------QQNKGRIVSP 530
+ G S S + ++ + R +SP
Sbjct: 278 VSFTDGSVRSGSGTDGSDEKKKERKRARGISP 309
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/207 (21%), Positives = 83/207 (40%), Gaps = 31/207 (14%)
Query: 385 KSEEGERKKRRARLQG------TSSHSADT----PEASLDSGEGPSGMASQGCPS----- 429
K+EE +R +R RL +SS S + PE + P A P
Sbjct: 96 KNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERI 155
Query: 430 -------ASRAETDDEDDEESDEEEEEEE------EEEEEEATDSEEE---EDLEQMQEG 473
ASR+ +++ S+E + E +E+ T++EEE ED+E+ +E
Sbjct: 156 GLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEV 215
Query: 474 QEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLL 533
+ED EE++E +E ++ ++ + E+ E ++ + G + S S
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 534 SEEPLAPSSIDAESNGEQPEELTLEEE 560
S+ + S + +E E +
Sbjct: 276 ESVSFTDGSVRSGSGTDGSDEKKKERK 302
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 65.9 bits (159), Expect = 1e-10
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 16/130 (12%)
Query: 400 GTSSHSADTPEASLDSGEG-PSGMASQGCPSASRA-----------ETDDEDDEESDEEE 447
G SS+S EA G P+G A C SAS +++DE DE +EEE
Sbjct: 213 GFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEE 272
Query: 448 EEEEEEEEEEATDSEE---EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
+ EE EEE+ SEE EED + +E +EDDE E+EEE G +G + P S +
Sbjct: 273 DSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDE-EEEEEMMVPGMEGKEEPGSDSGTTA 331
Query: 505 EKNLEPGKQI 514
L GKQ+
Sbjct: 332 VVALIRGKQL 341
Score = 35.4 bits (80), Expect = 0.19
Identities = 19/81 (23%), Positives = 39/81 (48%)
Query: 386 SEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE 445
S ++ R A+ + ++ EA + + + S+ AE ++++D+ +
Sbjct: 242 SSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEA 301
Query: 446 EEEEEEEEEEEEATDSEEEED 466
EE++EEEEEE E +E+
Sbjct: 302 EEDDEEEEEEMMVPGMEGKEE 322
Score = 30.4 bits (67), Expect = 6.2
Identities = 46/244 (18%), Positives = 88/244 (36%), Gaps = 7/244 (2%)
Query: 308 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 367
+LQ +DAF + +L + + T+D A D V
Sbjct: 89 KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEE 148
Query: 368 AMSRLDEVISKYAMLQDK----SEEGERKKRRARLQGTSSHSA--DTPEASLDSGEGPSG 421
A ++E++++Y K S+ G QG + + D+ + GP+
Sbjct: 149 ATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTA 208
Query: 422 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481
A G S S T+ E E + + ++ +++ +E +
Sbjct: 209 KAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268
Query: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 541
EEEE + ++ SS + NE++ E + + E++ + +V EEP + S
Sbjct: 269 EEEEDSEECSEEEDGYSSEEAENEED-EDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327
Query: 542 SIDA 545
A
Sbjct: 328 GTTA 331
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 65.9 bits (159), Expect = 1e-10
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 16/130 (12%)
Query: 400 GTSSHSADTPEASLDSGEG-PSGMASQGCPSASRA-----------ETDDEDDEESDEEE 447
G SS+S EA G P+G A C SAS +++DE DE +EEE
Sbjct: 213 GFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEE 272
Query: 448 EEEEEEEEEEATDSEE---EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
+ EE EEE+ SEE EED + +E +EDDE E+EEE G +G + P S +
Sbjct: 273 DSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDE-EEEEEMMVPGMEGKEEPGSDSGTTA 331
Query: 505 EKNLEPGKQI 514
L GKQ+
Sbjct: 332 VVALIRGKQL 341
Score = 35.4 bits (80), Expect = 0.19
Identities = 19/81 (23%), Positives = 39/81 (48%)
Query: 386 SEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE 445
S ++ R A+ + ++ EA + + + S+ AE ++++D+ +
Sbjct: 242 SSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEA 301
Query: 446 EEEEEEEEEEEEATDSEEEED 466
EE++EEEEEE E +E+
Sbjct: 302 EEDDEEEEEEMMVPGMEGKEE 322
Score = 30.4 bits (67), Expect = 6.2
Identities = 46/244 (18%), Positives = 88/244 (36%), Gaps = 7/244 (2%)
Query: 308 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 367
+LQ +DAF + +L + + T+D A D V
Sbjct: 89 KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEE 148
Query: 368 AMSRLDEVISKYAMLQDK----SEEGERKKRRARLQGTSSHSA--DTPEASLDSGEGPSG 421
A ++E++++Y K S+ G QG + + D+ + GP+
Sbjct: 149 ATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTA 208
Query: 422 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481
A G S S T+ E E + + ++ +++ +E +
Sbjct: 209 KAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268
Query: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 541
EEEE + ++ SS + NE++ E + + E++ + +V EEP + S
Sbjct: 269 EEEEDSEECSEEEDGYSSEEAENEED-EDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327
Query: 542 SIDA 545
A
Sbjct: 328 GTTA 331
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 63.9 bits (154), Expect = 5e-10
Identities = 60/207 (28%), Positives = 96/207 (46%), Gaps = 28/207 (13%)
Query: 436 DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
D+ED E +EEEEEE +E EE D EE+ + E+ +E E++EE++EEEE ++ +
Sbjct: 623 DNEDGFEEEEEEEEEMTDESEE--DGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEF 680
Query: 496 PMSSLQISNEKNLEPGKQISRSSGE-QQNKGRIVSPSLLSEE----------------PL 538
+SS +I + E K+ + S E + G + P LS + P
Sbjct: 681 LLSSEEIETKDEKEMDKENNDGSSEIGKAVGFLSVPKSLSSDSTLLLFKDSSSKMGYFPT 740
Query: 539 APSSIDAESNGEQPEEL-------TLEEESPVSQLFELEIEALPLDTPSSVETDISSSRK 591
S E++G+QP +L L +ES + FEL +P P + +T +S
Sbjct: 741 EEKSETDENSGKQPSKLDEDDSCSLLTKESSHNSSFELIGSTIPSYQPCNRQTGRGTSFF 800
Query: 592 QSEEPFTTVLEN--GAGMVSSTSFNGG 616
+ F + A +VSS S + G
Sbjct: 801 PTAGGFRSPSPGLFRASLVSSASKSSG 827
Score = 35.8 bits (81), Expect = 0.15
Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 9/120 (7%)
Query: 402 SSHSADTPEAS-LDSGEGPSGMAS---QGCPSASRAETDDEDDEESDEEEEEEEEEEEEE 457
+S A TP +S L+ E S M + S + D+++E+ +EE + +
Sbjct: 949 TSQDASTPASSELNKQEKESSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDN 1008
Query: 458 ATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRS 517
DS+E+E + + +D E+D+EEE +S Q+ K LE ++S S
Sbjct: 1009 EFDSDEDEHSDSGNDLALEDHEDDDEEELL-----KRSEKLKRQMRLRKYLEDEAEVSGS 1063
Score = 35.0 bits (79), Expect = 0.25
Identities = 61/268 (22%), Positives = 99/268 (36%), Gaps = 39/268 (14%)
Query: 433 AETDDEDDEESDEEEEEEEEEEEEEATDS--EEEEDLE------QMQEGQEDDEEEDE-- 482
AE D DE + EE +E EE+ D +E+L+ M+ +DD+ +
Sbjct: 1058 AEVSGSDVGSEDEYDGEEIDEYEEDVIDEVLPSDEELQSQIKKIHMKTMLDDDKRQLRLY 1117
Query: 483 EEEAAAGKDGDKSPMSSLQISNEKNLEPGKQIS---RSSGEQQNKGRIVSPSLLSEEPLA 539
+E A D ++ KN++ Q+ R S + Q + ++ SE
Sbjct: 1118 QERYLADGDLHSDGPGRMRKFRWKNIDDASQMDLFHRDSDDDQTEEQLDE----SEARWR 1173
Query: 540 PSSIDAES---NGEQPEELTLEEESPVSQ-----LFELEIEALPLDTPSSVETDISSSRK 591
I+ E + Q ++T EEE + + + ++ A L +S I S+
Sbjct: 1174 KERIEREQWLRDMAQQGKITAEEEEEIGEDSQFMILAKKVTAKALQKNASRPMVIQESKS 1233
Query: 592 QSEEPFTTVLENGAGMVSSTSF----------NGGVSPHNWGDSGPPCKKSRKEKKQTGS 641
PF + A V + S +S HN S P + SR T S
Sbjct: 1234 LLRNPFEAIRPGSAQQVKTGSLLNQPKAVLQKLAALSDHN--PSAP--RNSRNFVFHTLS 1289
Query: 642 GPLGNSYVERQRSVHEKNGKKICTLPSP 669
+ E +S +K G T PSP
Sbjct: 1290 PVKAEAAKESSKSQVKKRGPSFMTSPSP 1317
Score = 33.1 bits (74), Expect = 0.96
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 16/127 (12%)
Query: 402 SSHSADTPEASLDSGEGPS---GMASQGCPS----ASRAETDDEDDEESDEEEEEEEEEE 454
S AD+P DSG+G G S+G S+ + + ++SD E E+
Sbjct: 20 SQEEADSPS---DSGQGSYETIGPLSEGDSDEEIFVSKKLKNRKVLQDSDSETEDTNASP 76
Query: 455 EEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPM--SSLQISNEKNLEPGK 512
E+ DS EEE+ E + G+ + + A D D+S M S Q + E ++P
Sbjct: 77 EKTTYDSAEEENKENLYAGKNTKIKRIYKTVA----DSDESYMEKSLYQENLEAQVKPCL 132
Query: 513 QISRSSG 519
++S SG
Sbjct: 133 ELSLQSG 139
Score = 32.7 bits (73), Expect = 1.2
Identities = 47/198 (23%), Positives = 80/198 (40%), Gaps = 25/198 (12%)
Query: 417 EGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEE---EATDSEEEEDLEQM-QE 472
+GP M + A D +SD+++ EE+ +E E E E+ L M Q+
Sbjct: 1130 DGPGRMRKFRWKNIDDASQMDLFHRDSDDDQTEEQLDESEARWRKERIEREQWLRDMAQQ 1189
Query: 473 GQEDDEEEDEEEE---------AAAGKDGDKSPMSSLQISNEKNL--EPGKQISRSSGEQ 521
G+ EEE+E E K K+ + I K+L P + I S +Q
Sbjct: 1190 GKITAEEEEEIGEDSQFMILAKKVTAKALQKNASRPMVIQESKSLLRNPFEAIRPGSAQQ 1249
Query: 522 QNKGRIVS---------PSLLSEEPLAP-SSIDAESNGEQPEELTLEEESPVSQLFELEI 571
G +++ +L P AP +S + + P + +ES SQ+ +
Sbjct: 1250 VKTGSLLNQPKAVLQKLAALSDHNPSAPRNSRNFVFHTLSPVKAEAAKESSKSQVKKRGP 1309
Query: 572 EALPLDTPSSVETDISSS 589
+ +P ++TD S+S
Sbjct: 1310 SFMTSPSPKHLKTDDSTS 1327
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 63.9 bits (154), Expect = 5e-10
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 11/81 (13%)
Query: 435 TDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDK 494
+DDED+EE +E EEEEEE EEEE D EEEE +EEE+EEEE G+K
Sbjct: 358 SDDEDEEEEEEGEEEEEEAEEEEEEDEEEEE-----------EEEEEEEEEPQQRGQGEK 406
Query: 495 SPMSSLQISNEKNLEPGKQIS 515
S S +I + EP +S
Sbjct: 407 SATPSRKILDPNTGEPAPVLS 427
Score = 31.6 bits (70), Expect = 2.8
Identities = 54/241 (22%), Positives = 92/241 (38%), Gaps = 46/241 (19%)
Query: 242 LKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKP-------GPDTFPDYGDVLRAVE 294
L + + G + E +P G +P + + P +TF + G V A
Sbjct: 200 LAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRVINLNDNTFTEKGAVAMAET 259
Query: 295 KAAARH----SLG--LPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGV 348
R + G L R + + DA R +L+E L+L + C + D V
Sbjct: 260 LKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKE---LNLSF---CEIKRDAALAV 313
Query: 349 DPALSDPVLARRLRENRSL----AMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSH 404
A++D +L N + +L EV+ + M + +S
Sbjct: 314 AEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKV----------------LASL 357
Query: 405 SADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEE--EEEEEATDSE 462
S D E + GE A + E ++E++EE +EEEEE ++ + E+ AT S
Sbjct: 358 SDDEDEEEEEEGEEEEEEAEE-----EEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSR 412
Query: 463 E 463
+
Sbjct: 413 K 413
Score = 30.0 bits (66), Expect = 8.1
Identities = 40/169 (23%), Positives = 68/169 (40%), Gaps = 18/169 (10%)
Query: 429 SASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAA 488
+ + A D + E+ D EE E+ + E ++ ++ DDE+E+EEEE
Sbjct: 312 AVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEE--- 368
Query: 489 GKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESN 548
G++ + + E E ++ E Q +G+ + S + L P++
Sbjct: 369 ---GEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNT------ 419
Query: 549 GEQPEELTLEEESPVSQL--FELEIEALPLDTPSSV----ETDISSSRK 591
GE L+ + VS F + L L SSV +TD S K
Sbjct: 420 GEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEK 468
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 63.2 bits (152), Expect = 9e-10
Identities = 63/261 (24%), Positives = 109/261 (41%), Gaps = 63/261 (24%)
Query: 396 ARLQGTSSHSADTPEASLDSGEGPSGMA--SQGCPSASRAETDDEDDEESDEEEEEEEEE 453
A+ T TP +L + G G A ++G + A+ +D D+EE D+ EE+EE++
Sbjct: 101 AKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDD 160
Query: 454 EEEE------------------ATDSEEEEDLEQMQEGQEDDEEEDEEEEA-----AAGK 490
E+E+ A++ E++ED ++ E +DDEE+D EEEA A GK
Sbjct: 161 EDEDEDEDEIEPAAMKAAAAAPASEDEDDED-DEDDEDDDDDEEDDSEEEAMETTPAKGK 219
Query: 491 DGDK-SPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNG 549
K P+ + ++ +++ E + ++ ++ D E +
Sbjct: 220 KAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE-----------------DDDDEDDE 262
Query: 550 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 609
E+ EE EEE PV + P + +++ + E V G
Sbjct: 263 EEEEE---EEEEPVK------------EAPGKRKKEMAKQKAAPEAKKQKV----EGTEP 303
Query: 610 STSFNGGVSPHNWGDSGPPCK 630
+T+FN V N+ S P K
Sbjct: 304 TTAFNLFVGNLNFNKSAPELK 324
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/164 (20%), Positives = 77/164 (46%), Gaps = 28/164 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K+ + +K+ + S + + D E A+ +A+ A D++D+++ D
Sbjct: 135 KNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194
Query: 445 EEEEEEEEEE--EEEATDS------------------------EEEEDLEQMQEGQEDDE 478
+E+++++EE+ EEEA ++ EEE+D ++ + EDDE
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE 254
Query: 479 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQ 522
++D+E++ ++ ++ P+ + ++ E KQ + ++Q
Sbjct: 255 DDDDEDDEEEEEEEEEEPVK--EAPGKRKKEMAKQKAAPEAKKQ 296
Score = 50.4 bits (119), Expect = 6e-06
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 40/144 (27%)
Query: 388 EGERKKRRARLQGTSSHSADTPEASLDSGEG---------PSGMASQGCPSASRAETDDE 438
+G + + A+ + + D E + E P+ M + AS E D++
Sbjct: 132 KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDED 191
Query: 439 D----DEESDEEEEEEE---------------------------EEEEEEATDSEEEEDL 467
D D++ DEE++ EE E+EEE+ D ++++D
Sbjct: 192 DEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251
Query: 468 EQMQEGQEDDEEEDEEEEAAAGKD 491
+ + EDDEEE+EEEE K+
Sbjct: 252 DDEDDDDEDDEEEEEEEEEEPVKE 275
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/122 (20%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Query: 407 DTPEASLDSGEGPSGMASQGCPSASRAETDDED---DEESDEEEEEEEEEEEEEATDSEE 463
D+ E ++++ A++ P ++ +DED D+E ++++++E++E++++ D EE
Sbjct: 205 DSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEE 264
Query: 464 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 523
EE+ E+ + + + E + A + K + + + NL G S +
Sbjct: 265 EEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELK 324
Query: 524 KG 525
G
Sbjct: 325 TG 326
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 62.8 bits (151), Expect = 1e-09
Identities = 44/120 (36%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 387 EEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEE 446
E+G +K DT +A LD E MAS + +E+ EE
Sbjct: 477 EQGVPEKEETPPPVEPEEEEDTEDAGLDDWEA---MASDEETEKVEGNKVHIEVKENPEE 533
Query: 447 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDE-EEEAAAGKDGDKSPMSSLQISNE 505
EEEEEEEEEE+ +SEEEE+ E EG E DEE+++ +E +GK DK P + +E
Sbjct: 534 EEEEEEEEEED-EESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592
Score = 48.9 bits (115), Expect = 2e-05
Identities = 65/304 (21%), Positives = 125/304 (41%), Gaps = 55/304 (18%)
Query: 349 DPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSE-EGERKKRRARLQGTSSHSAD 407
D + +A++ E + + DE +K L++K E E +K + + + +
Sbjct: 220 DASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEE 279
Query: 408 TPEA--SLDSGEGPSGMASQGCPSASRAETDDEDDEESDE------EEEEEEEE------ 453
T ++ ++D+G P+ P+A AE D+E D++ + E+EE+E+E
Sbjct: 280 TVKSKVTVDTGVIPASEEKAETPTA--AEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS 337
Query: 454 ---------------EEEEATDSEEEEDLEQMQ--EGQEDDEEEDEEEEAAAGKDGDKSP 496
EEEE EEEE +++++ E + +EE E+E+ K +K
Sbjct: 338 KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKE- 396
Query: 497 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---------IDAES 547
E+ + GK +++S E + + L ++ PS + +
Sbjct: 397 ------RKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKK 450
Query: 548 NGEQPEELTLEEESPVSQLFEL--EIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGA 605
+ P++L E VS+ EL +E + P ET ++ E+ L++
Sbjct: 451 RKKIPQQL---ESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWE 507
Query: 606 GMVS 609
M S
Sbjct: 508 AMAS 511
Score = 47.4 bits (111), Expect = 5e-05
Identities = 48/189 (25%), Positives = 90/189 (47%), Gaps = 30/189 (15%)
Query: 356 VLARRLRENRSLAMSRLD-------EVISKYAMLQDKSEEGERKKRRARLQGTSSHSADT 408
+L + RE R+ A + L EV SK ++ + + ++K+++ Q S +++
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466
Query: 409 PE--ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS----- 461
E A+++ E + P E +D +D D+ E +EE E+ +
Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE 526
Query: 462 ------EEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEK------NLE 509
EEEE+ E+ +E +E +EEE+EE E + G +GD+ ++S+EK + +
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGE-SEGSEGDE---EDEKVSDEKDSGKTLDKK 582
Query: 510 PGKQISRSS 518
P K++S S
Sbjct: 583 PSKEMSSDS 591
Score = 39.3 bits (90), Expect = 0.013
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 13/91 (14%)
Query: 434 ETDDEDDEESDEEEEE------EEEEEEEEATDSE------EEEDLEQMQEGQEDDEEED 481
E ++ED+E +EEEEE E +EE+E+ +D + +++ ++M E D ++D
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDD 598
Query: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGK 512
+E A D K + ++ + KN+ K
Sbjct: 599 RTKEERA-YDKAKRRIEKRRLEHSKNVNTEK 628
Score = 38.1 bits (87), Expect = 0.030
Identities = 55/278 (19%), Positives = 117/278 (42%), Gaps = 46/278 (16%)
Query: 435 TDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE--------------QMQEGQEDDEEE 480
T++ ++E + ++++++ ++ ++++ D + E+LE +M G +DD++
Sbjct: 84 TENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDF 143
Query: 481 DEEEEAAAGK-------------DGDKS----PMSSLQISNEKNLEPGKQISRSSGEQQN 523
++ + A GK D D S S + S E E + + G+++N
Sbjct: 144 NKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKN 203
Query: 524 KGRIVSPSLLS--EEPLAPSSID--AESNGEQPEELTLEEESPVSQLFELEIEALPLDTP 579
+ P++ S E+ A I A+ E+ E + + ++L +L+ E L+T
Sbjct: 204 QKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK-EKEELETG 262
Query: 580 SSVET-DISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQ 638
++ S RK EE + + G++ + S +P D KK + +KK+
Sbjct: 263 KKDQSKQKESQRKFEEETVKSKVTVDTGVIPA-SEEKAETPTAAEDDNEGDKKKKDKKKK 321
Query: 639 TGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLASL 676
G + ++ +K G T+ + LA L
Sbjct: 322 KGE--------KEEKEKEKKKGPSKATVKAMQEALAKL 351
Score = 36.6 bits (83), Expect = 0.086
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
Query: 434 ETDDEDDEESDEEEEEE--------------EEEEEEEATDSEEEEDLEQMQEGQEDDEE 479
E ++E+DEES+EEEEEE +E++ +++ E + + D ++
Sbjct: 538 EEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDD 597
Query: 480 EDEEEEAAAGKDGDKSPMSSLQISNEKNLE 509
+ +EE A K + L+ S N E
Sbjct: 598 DRTKEERAYDKAKRRIEKRRLEHSKNVNTE 627
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 62.4 bits (150), Expect = 1e-09
Identities = 56/206 (27%), Positives = 91/206 (44%), Gaps = 29/206 (14%)
Query: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
P A + + + +EEEEEE+EEEEEE +EEE+ E+ +E +E++EEE+EEEEAA
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEE----DEEEEEEEEEEEEEEEEEEEEEEEAA 773
Query: 488 AG---------KDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
A + G S S + P ++ E + + + L EE
Sbjct: 774 AAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEE-- 831
Query: 539 APSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFT 598
++ S G+ + E +P + ++ L TP + S+ EP T
Sbjct: 832 GSKTLVLVSPGDMKKSPVTAELAP-----DPDLGTLAALTPQHERPQPTGSQLDVSEPGT 886
Query: 599 --TVLEN-------GAGMVSSTSFNG 615
+VL++ GAG+ + T G
Sbjct: 887 LSSVLKSEPKPPGPGAGLGAGTVTTG 912
Score = 33.9 bits (76), Expect = 0.56
Identities = 61/270 (22%), Positives = 102/270 (37%), Gaps = 58/270 (21%)
Query: 365 RSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMAS 424
RSL R++ S+ D E ++ R L G+ S A + + P+ M S
Sbjct: 447 RSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQ--------PAQMLS 498
Query: 425 QGCPSASRAETDDEDDEESDEEEE-----------EEEEEEEEEATDSEEEEDLEQMQEG 473
A R + D S E+E EEE+ + +E ++E +L+ G
Sbjct: 499 VDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPG 558
Query: 474 QE------DDEEEDE--------EEEAAAGKDGDKSPMS-SLQISNEKNLEP------GK 512
E DEE +E EE G + P S+Q E++L+
Sbjct: 559 AEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPP 618
Query: 513 QISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFEL--- 569
Q+S+ G + + +P S PL +G +P + P Q+F +
Sbjct: 619 QLSQGDGRSET-SQPPTPGSPSHSPL--------HSGPRPRRRESDPTGPQRQVFSVAPP 669
Query: 570 -EIEALPLDTPSSV-----ETDISSSRKQS 593
E+ LP P S+ + D+S R+++
Sbjct: 670 FEVNGLPRAVPLSLPYQDFKRDLSDYRERA 699
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/175 (29%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Query: 400 GTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEAT 459
G++S +A E + + GEG G +G R + +EEEEEEEE+E +E
Sbjct: 16 GSASAAAAAAENNGERGEGERGAGGRG-----RRHSRPHYCSAGEEEEEEEEEDEIQEVQ 70
Query: 460 DSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSG 519
+ +EE+ E G E+DEEE+EEEE D P S E EP I+
Sbjct: 71 ITGDEEEEEDGGGGLEEDEEEEEEEEMGLDWDEPLEPEDS--AGEELEPEPVHMINMDQS 128
Query: 520 ---EQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEI 571
E + R+++P P S +D + ++PE L E + ++ + + I
Sbjct: 129 AALEPEAPPRLLAPRARGGPPGDGSELDPDVL-QRPERARLSENTRLATRYAVRI 182
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 62.4 bits (150), Expect = 1e-09
Identities = 88/383 (22%), Positives = 147/383 (38%), Gaps = 67/383 (17%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEA-----------SLDSGEGPSGMASQGCPSA 430
+ ++ EE ER++ R + P+ LDSG S S
Sbjct: 987 VDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESL---SE 1043
Query: 431 SRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGK 490
+ T++E++ E +EEEE++++++ ++ +SE +++ + E E DE + +EEE +
Sbjct: 1044 EQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIV 1103
Query: 491 DGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNK--GRIVSPSLLSEEPLAPSSI----- 543
SS + S E + S SS E + + R EE +A S+
Sbjct: 1104 TSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGP 1163
Query: 544 -DAESNGEQP---------EELTLEEESPVSQLFELEIEAL-PLDTPSSVE--------T 584
D E +GE+ + L +EEE ++E EA+ P + PS ++
Sbjct: 1164 EDFEQDGEEAALAPGAPAVDSLGMEEE------VDIETEAVAPEERPSMLDEPPLPVGVE 1217
Query: 585 DISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPL 644
+ + SR+ EEP + + GA ++S P ++ PP R + P
Sbjct: 1218 EPADSREPPEEP--GLSQEGAMLLSPE------PPAKEVEARPPLSPERAPEHDLEVEPE 1269
Query: 645 GNSYVERQRSVHEKNGKKICTLPSPPSPL-------ASLAPVADSSTRVDSPSH--GLVT 695
+ + P PPSP AS V D P H GL
Sbjct: 1270 PPMMLPLPLQPPLPPPRP----PRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG 1325
Query: 696 SSLCIPSPARLSQTPHSQPPRPG 718
S S + TP +PP G
Sbjct: 1326 SLAKSQSTETVPATPGGEPPLSG 1348
Score = 43.1 bits (100), Expect = 0.001
Identities = 75/352 (21%), Positives = 118/352 (33%), Gaps = 55/352 (15%)
Query: 419 PSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATD------------------ 460
PS + P + + D + S +EE+EE E E D
Sbjct: 960 PSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGV 1019
Query: 461 ---------------SEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNE 505
+E+E L + QE E++EE +EEEE D D + +E
Sbjct: 1020 RRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE 1079
Query: 506 KNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPV 563
E ++ S E++ + S + + + S + ES+ E + +EE V
Sbjct: 1080 DTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVV 1139
Query: 564 SQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWG 623
++ E E E + S+ + +Q E L GA V S V
Sbjct: 1140 AREEEEEEEEEEMVAEESMASAGPEDFEQDGE--EAALAPGAPAVDSLGMEEEVDI---- 1193
Query: 624 DSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKK----ICTLPSPPS-------P 672
++ + R P+G R E+ G + P PP+ P
Sbjct: 1194 ETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPP 1253
Query: 673 LA-SLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTS 723
L+ AP D + P ++ L P P P S PP P T S
Sbjct: 1254 LSPERAPEHDLEVEPEPPM--MLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 62.0 bits (149), Expect = 2e-09
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+ + EEGE ++ +G E + GEG +G E ++E + E
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEG------EGEEEEGEGEGEEEGEGE 894
Query: 443 SDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGD---KSPMSS 499
+EEE E E EEE E EEE + + +EG+E + E +EEE G+DG+ +
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954
Query: 500 LQISNEKNLEPGKQISRSSGEQ-QNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLE 558
+ E+ G++ GE+ + +G EE + E GE+ E E
Sbjct: 955 WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014
Query: 559 EE 560
EE
Sbjct: 1015 EE 1016
Score = 60.5 bits (145), Expect = 6e-09
Identities = 43/145 (29%), Positives = 64/145 (44%), Gaps = 5/145 (3%)
Query: 385 KSEEGERKKR-RARLQGTSSHSADTPEASLDSGEGPSGMASQGCP----SASRAETDDED 439
+ EEGERKK RA + D E + EG +G + + E+
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828
Query: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
+EE E EEEE E EEEE EEE + + +EG+E + EE+ EE G++ +
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888
Query: 500 LQISNEKNLEPGKQISRSSGEQQNK 524
+ E E G+ GE + +
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGE 913
Score = 57.4 bits (137), Expect = 5e-08
Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 12/182 (6%)
Query: 384 DKSEEGERKKRRARLQGTSSHSADTPEAS----LDSGEGPSGMASQGCPSASRAETDDED 439
++ E+GE+ K R ++ + E D E QG E ++
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLE-QMQEGQEDDEEEDEEEEAAAGKDGDKSPMS 498
+EE E EEEE + EEEE + E +E+ E + EG+ + EE + ++E AGK+ +K
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKE-EKGEEE 790
Query: 499 SLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLE 558
Q E+ G+ GE++ +G V + E + E GE+ E E
Sbjct: 791 GDQGEGEEEETEGR------GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE 844
Query: 559 EE 560
EE
Sbjct: 845 EE 846
Score = 57.0 bits (136), Expect = 6e-08
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+ + EEGE + +G E + GEG +G E ++E+ E
Sbjct: 931 EGEEEEGEGEGEDG--EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 443 SDEEEEEEEE-------EEEEEATDSEEEE-DLEQMQEGQEDDEEEDEEEEAAAGKDGDK 494
EEEE EEE EEE E EEEE ++E EG+E + E +EEE G++ +K
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Query: 495 SPMSSLQISNEKNLEPGKQISRSSGEQQNK 524
N + E + + +GE++N+
Sbjct: 1049 EGEGEENRRNREEEEEEEGKYQETGEEENE 1078
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/197 (26%), Positives = 82/197 (41%), Gaps = 29/197 (14%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+ + EEGE K +G + E + GEG G +G E + E +EE
Sbjct: 911 EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEG-EGEEEEGEWEGEEEEGEGEGEEE 969
Query: 443 SDEEEEE------------EEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGK 490
+ E EE E EEEE E + EEE + E+ EG+ ++EEE E E G+
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEGE-EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE 1028
Query: 491 DGDKSPMSSLQISNEKNLEPGKQISR-SSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNG 549
+G+ + E+ E G++ + GE+ + R EE E+
Sbjct: 1029 EGEG------EGEEEEGEEEGEEREKEGEGEENRRNR--------EEEEEEEGKYQETGE 1074
Query: 550 EQPEELTLEEESPVSQL 566
E+ E EE VS++
Sbjct: 1075 EENERQDGEEYKKVSKI 1091
Score = 50.8 bits (120), Expect = 4e-06
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 21/186 (11%)
Query: 383 QDKSEEGERKKRRARL-QGTSSHSADTPEASLDSGEGP------SGMASQGCPSASRAET 435
+ + EEG+R++ + +G + E + EG +G +G + E
Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796
Query: 436 DDEDDEESDEEEEEEEEEEEEEATDS-----EEEEDLEQMQEGQEDDEEEDE-EEEAAAG 489
++E+ E EE+EE E E E + EEEE+ E +E E +EEE E EEE G
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Query: 490 KDGDKSPMSSLQISNEKNLEPG-KQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESN 548
K ++ + E+ G ++ GE++ +G EE + E
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE-------GEEEEGEGEGEEEGE 909
Query: 549 GEQPEE 554
GE EE
Sbjct: 910 GEGEEE 915
Score = 50.1 bits (118), Expect = 8e-06
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 19/163 (11%)
Query: 388 EGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEE 447
EGE ++ +G + E + E G + E + E+ E EEE
Sbjct: 978 EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEE 1037
Query: 448 EEEEEEEEEEA----------TDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPM 497
E EEE EE E + EEEE+ + + G+E++E +D EE K
Sbjct: 1038 EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK-----IK 1092
Query: 498 SSLQISNEKNLEPGKQISRSSG---EQQNKGRIVSPSLLSEEP 537
S++ K + K ++ + G EQ++K + S LL P
Sbjct: 1093 GSVKYGKHKTYQK-KSVTNTQGNGKEQRSKMPVQSKRLLKNGP 1134
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 11/184 (5%)
Query: 374 EVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRA 433
EV A ++E+G + + SS + + + GE G P
Sbjct: 635 EVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEK 694
Query: 434 ETDDEDD---EESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGK 490
E ++++ + +E+E++E E+ ++ + E EE E+ E++E + EEEE G+
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Query: 491 DGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGE 550
K ++ E+ E G++ ++ KG EE + E GE
Sbjct: 755 --GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE------ETEGRGE 806
Query: 551 QPEE 554
+ EE
Sbjct: 807 EKEE 810
Score = 47.8 bits (112), Expect = 4e-05
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 8/182 (4%)
Query: 385 KSEEGERKKRRARLQG----TSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDD 440
K +GE ++++ R QG + + E GE G + + + E +
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762
Query: 441 EESDEEEEEEEEEEEEEATDSEE--EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMS 498
E E E+EE E ++EE EE EE+ +Q + +E+ E EE+E +G +
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Query: 499 SLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLE 558
+ E+ G++ E++ +G EE + E GE+ E E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE--EGEEGEGEEEGEEGEGEGEE 880
Query: 559 EE 560
EE
Sbjct: 881 EE 882
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/158 (28%), Positives = 70/158 (44%), Gaps = 32/158 (20%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+ + EEGE + +G E + GEG G +G E ++E +EE
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEG---EGEGEEGEG-EGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 443 SDEEEE-----EEEEE---------EEEEATDSEEE-----EDLEQMQEGQED--DEEED 481
+ EEE EEEEE EE E EEE E+ E+ EG+E+ + EE+
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062
Query: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSG 519
EEEE + G++ + ++ E K++S+ G
Sbjct: 1063 EEEEGKYQETGEEE-------NERQDGEEYKKVSKIKG 1093
Score = 36.2 bits (82), Expect = 0.11
Identities = 55/247 (22%), Positives = 94/247 (38%), Gaps = 21/247 (8%)
Query: 435 TDDEDDEESDEEEEEEE--EEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 492
T D E+D+ +E EE E +E +A + + Q + DEE E K+G
Sbjct: 533 TQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEG 592
Query: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSE----EPLAPSSIDAESN 548
+ S E+ +E ++ + G ++ K I+S L + E A S +AE
Sbjct: 593 AED--SKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDG 650
Query: 549 GEQPEELTLEEESPVSQLFELEIEAL--------PLDTPSSVETDISSS----RKQSEEP 596
E + T EE S ++ ++ E ++ P E +++ ++ EE
Sbjct: 651 PEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQ 710
Query: 597 FTTVLENGAGMVSSTSFN-GGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSV 655
E G + GG H G+ ++ +EK+ G VE +R
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770
Query: 656 HEKNGKK 662
E KK
Sbjct: 771 EEGERKK 777
Score = 30.8 bits (68), Expect = 4.7
Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 12/116 (10%)
Query: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQM 470
+ + G+ SQG A T + +E E EE+E E+ + EE+E
Sbjct: 551 SEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQE----- 605
Query: 471 QEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGR 526
E +EE G +K+ + S ++++ + GK S E +GR
Sbjct: 606 -------VEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGR 654
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 294
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 295 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 340
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 341 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ 396
Query: 558 E 558
E
Sbjct: 397 E 397
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 26/169 (15%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
LQD S+ ERK A S S E + E G S+ S E ++E++E
Sbjct: 255 LQDISDS-ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE--ESEEEEEEEEEEEE 311
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG-----------QEDDEEEDEEEEAAAG- 489
E+ EE E+ EE ++ E ED E+ E ++ E E+ EEE G
Sbjct: 312 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 371
Query: 490 ------KDGDKSP----MSSLQISNE-KNLEPGKQISRSSGEQQNKGRI 527
+GD P +S +++ E P Q RS E Q RI
Sbjct: 372 PQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRI 420
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD----- 437
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 183 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 241
Query: 438 --EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
E EE D + ++ + E T S E E +E++EEE+EEEE + + +
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301
Query: 496 PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE----PLAPSSIDAESNGEQ 551
+ E+ ++ S S E+ ++ + E + S D +S +
Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 361
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 362 EAEEEVGEGTPQS 374
Score = 36.6 bits (83), Expect = 0.086
Identities = 48/230 (20%), Positives = 91/230 (39%), Gaps = 13/230 (5%)
Query: 378 KYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD 437
K+A +++K E ER+KR Q + + + E + + + E
Sbjct: 109 KHARVKEKEREHERRKRHREEQDKARREWERQKRR----EMAREHSRRERDRLEQLERKR 164
Query: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQE--GQEDDEEEDEEEEAAA---GKDG 492
E + + E+++E+ E++E E E ++ E +E ED ++ A +
Sbjct: 165 ERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 224
Query: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQP 552
+ P ++ + + +P K+ + + + +S S SS ++ S E+
Sbjct: 225 PRPPRERFELGDGR--KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 282
Query: 553 EELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLE 602
EE EEE S E E E + E S+S + SE+ V E
Sbjct: 283 EEEEEEEEEEGSTSEESEEE--EEEEEEEEEETGSNSEEASEQSAEEVSE 330
Score = 32.7 bits (73), Expect = 1.2
Identities = 39/182 (21%), Positives = 75/182 (41%), Gaps = 25/182 (13%)
Query: 363 ENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGE-GPSG 421
E S + LDE++ + +++ E+ E K+ + +S D+ SL+ GE
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLK------NSDDRDSKRDSLEEGELRDHC 57
Query: 422 MASQGCPSASRAETDDEDDEESDE-----------------EEEEEEEEEEEEATDSEEE 464
M S R E ED E D+ ++E+ +E++ A E+E
Sbjct: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKE 117
Query: 465 EDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNK 524
+ E+ + +E+ ++ E E ++ + S + + LE ++ R EQQ +
Sbjct: 118 REHERRKRHREEQDKARREWERQKRREMARE-HSRRERDRLEQLERKRERERKMREQQKE 176
Query: 525 GR 526
R
Sbjct: 177 QR 178
Score = 30.8 bits (68), Expect = 4.7
Identities = 51/242 (21%), Positives = 89/242 (36%), Gaps = 26/242 (10%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASL-DSGEGPSGMASQGCPSASRAET----DD 437
+D EEGE + + T +S E S+ D GE +A + SR E D
Sbjct: 45 RDSLEEGELRDHCMEI--TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD 102
Query: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPM 497
E +E +E+E E E EE+D + + + E + E A ++ +
Sbjct: 103 EKRKEKKHARVKEKEREHERRKRHREEQD-----KARREWERQKRREMAREHSRRERDRL 157
Query: 498 SSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSI------DAESNGEQ 551
L+ E+ + +Q + EQ+ + R E S + S+ +
Sbjct: 158 EQLERKRERERKMREQ-QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 216
Query: 552 PEELTLEEESPVSQLFELEIEALPLDTPSSVE-------TDISSSRKQSEEPFTTVLENG 604
+ P + FEL P+ E DIS S +++ ++ E+G
Sbjct: 217 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 276
Query: 605 AG 606
+G
Sbjct: 277 SG 278
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 303
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 304 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 349
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 350 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ 405
Query: 558 E 558
E
Sbjct: 406 E 406
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/268 (22%), Positives = 103/268 (38%), Gaps = 26/268 (9%)
Query: 286 YGDVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYR 345
+ D L +E+ R +Q+ Q ++ R R +ER + + +DY
Sbjct: 162 FRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS 221
Query: 346 PGVDPALSDPVLARRLRENRSLAMSRL---DEVISKYAMLQDKSEEGERKKRRARLQGTS 402
V + R RE L R +E + + +L D + + +++ + + +S
Sbjct: 222 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 281
Query: 403 SHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSE 462
+ S E + E S S E ++E++EE+ EE E+ EE ++ E
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEE 341
Query: 463 EEEDLEQMQEG-----------QEDDEEEDEEEEAAAG-------KDGDKSP----MSSL 500
ED E+ E ++ E E+ EEE G +GD P +S +
Sbjct: 342 MSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPI 401
Query: 501 QISNE-KNLEPGKQISRSSGEQQNKGRI 527
++ E P Q RS E Q RI
Sbjct: 402 ELKQELPKYLPALQGCRSVEEFQCLNRI 429
Score = 40.0 bits (92), Expect = 0.008
Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 192 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 250
Query: 443 SDEEEEEEEEEEE-EEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501
+E+ EE + + ++ +DSE + + + E+EEEE ++ + S +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310
Query: 502 ISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEP----------LAPSSIDAESNGEQ 551
E+ E + S S + VS +SE+ + S D +S +
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 370
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 371 EAEEEVGEGTPQS 383
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/239 (20%), Positives = 90/239 (37%), Gaps = 22/239 (9%)
Query: 378 KYAMLQDKSEEGERKKR------RARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSAS 431
K+A +++K E ER+KR +AR + + G G+ C
Sbjct: 109 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGV----CLFRD 164
Query: 432 RAE-----TDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEA 486
R E + E ++E+ E++E E A + +E + + ED ++
Sbjct: 165 RLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 224
Query: 487 AA---GKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSI 543
A + + P ++ + + +P K+ + + + +S S SS
Sbjct: 225 KASHWSRSPPRPPRERFELGDGR--KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 282
Query: 544 DAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLE 602
++ S E+ EE EEE S E E E + E S+S + SE+ V E
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEEEEETGSNSEEASEQSAEEVSE 339
Score = 34.7 bits (78), Expect = 0.33
Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 13/150 (8%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASL-DSGEGPSGMASQGCPSASRAET-----D 436
+D EEGE + + T +S E S+ D GE +A + SR E D
Sbjct: 45 RDSLEEGELRDHCMEI--TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD 102
Query: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 496
++ E+ +E+E E E EE++ + E Q+ E E G DG
Sbjct: 103 EKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDG---- 158
Query: 497 MSSLQISNEKNLEPGKQISRSSGEQQNKGR 526
L + LE ++ R EQQ + R
Sbjct: 159 -VCLFRDRLEQLERKRERERKMREQQKEQR 187
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 271
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 272 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 317
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 318 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ 373
Query: 558 E 558
E
Sbjct: 374 E 374
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 26/169 (15%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
LQD S+ ERK A S S E + E G S+ S E ++E++E
Sbjct: 232 LQDISDS-ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE--ESEEEEEEEEEEEE 288
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG-----------QEDDEEEDEEEEAAAG- 489
E+ EE E+ EE ++ E ED E+ E ++ E E+ EEE G
Sbjct: 289 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 348
Query: 490 ------KDGDKSP----MSSLQISNE-KNLEPGKQISRSSGEQQNKGRI 527
+GD P +S +++ E P Q RS E Q RI
Sbjct: 349 PQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRI 397
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD----- 437
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 160 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 218
Query: 438 --EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
E EE D + ++ + E T S E E +E++EEE+EEEE + + +
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278
Query: 496 PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE----PLAPSSIDAESNGEQ 551
+ E+ ++ S S E+ ++ + E + S D +S +
Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 338
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 339 EAEEEVGEGTPQS 351
Score = 36.6 bits (83), Expect = 0.086
Identities = 48/230 (20%), Positives = 91/230 (39%), Gaps = 13/230 (5%)
Query: 378 KYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD 437
K+A +++K E ER+KR Q + + + E + + + E
Sbjct: 86 KHARVKEKEREHERRKRHREEQDKARREWERQKRR----EMAREHSRRERDRLEQLERKR 141
Query: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQE--GQEDDEEEDEEEEAAA---GKDG 492
E + + E+++E+ E++E E E ++ E +E ED ++ A +
Sbjct: 142 ERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 201
Query: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQP 552
+ P ++ + + +P K+ + + + +S S SS ++ S E+
Sbjct: 202 PRPPRERFELGDGR--KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 259
Query: 553 EELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLE 602
EE EEE S E E E + E S+S + SE+ V E
Sbjct: 260 EEEEEEEEEEGSTSEESEEE--EEEEEEEEEETGSNSEEASEQSAEEVSE 307
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 260
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 261 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 306
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 307 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ 362
Query: 558 E 558
E
Sbjct: 363 E 363
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 26/169 (15%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
LQD S+ ERK A S S E + E G S+ S E ++E++E
Sbjct: 221 LQDISDS-ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE--ESEEEEEEEEEEEE 277
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG-----------QEDDEEEDEEEEAAAG- 489
E+ EE E+ EE ++ E ED E+ E ++ E E+ EEE G
Sbjct: 278 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 337
Query: 490 ------KDGDKSP----MSSLQISNE-KNLEPGKQISRSSGEQQNKGRI 527
+GD P +S +++ E P Q RS E Q RI
Sbjct: 338 PQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRI 386
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD----- 437
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 149 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 207
Query: 438 --EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
E EE D + ++ + E T S E E +E++EEE+EEEE + + +
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267
Query: 496 PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE----PLAPSSIDAESNGEQ 551
+ E+ ++ S S E+ ++ + E + S D +S +
Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 327
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 328 EAEEEVGEGTPQS 340
Score = 34.3 bits (77), Expect = 0.43
Identities = 59/267 (22%), Positives = 101/267 (37%), Gaps = 37/267 (13%)
Query: 369 MSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASL-DSGEGPSGMASQGC 427
MS+ D+ SK +D EEGE + R + T +S E S+ D GE +A +
Sbjct: 1 MSQSDDRDSK----RDSLEEGELRDHRMEI--TIRNSPYRREDSMEDRGEEDDSLAIKPP 54
Query: 428 PSASRAET-----DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE---- 478
SR E D++ E+ +E+E E E EE++ + E Q+ E
Sbjct: 55 QQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMARE 114
Query: 479 ----EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRI------- 527
E D E+ ++ ++ M Q + E ++ E++ + +
Sbjct: 115 HSRRERDRLEQLERKRERERK-MREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 173
Query: 528 -------VSPSLLSEEPLAPSSIDAE-SNGEQP-EELTLEEESPVSQLFELEIEALPLDT 578
V S S P P E +G +P +E +EE +S L ++ +
Sbjct: 174 REDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSS 233
Query: 579 PSSVETDISSSRKQSEEPFTTVLENGA 605
S + S ++ EE E G+
Sbjct: 234 AESSSAESGSGSEEEEEEEEEEEEEGS 260
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 305
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 306 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 351
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 352 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ 407
Query: 558 E 558
E
Sbjct: 408 E 408
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 26/169 (15%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
LQD S+ ERK A S S E + E G S+ S E ++E++E
Sbjct: 266 LQDISDS-ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE--ESEEEEEEEEEEEE 322
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG-----------QEDDEEEDEEEEAAAG- 489
E+ EE E+ EE ++ E ED E+ E ++ E E+ EEE G
Sbjct: 323 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 382
Query: 490 ------KDGDKSP----MSSLQISNE-KNLEPGKQISRSSGEQQNKGRI 527
+GD P +S +++ E P Q RS E Q RI
Sbjct: 383 PQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRI 431
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD----- 437
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 194 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 252
Query: 438 --EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
E EE D + ++ + E T S E E +E++EEE+EEEE + + +
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312
Query: 496 PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE----PLAPSSIDAESNGEQ 551
+ E+ ++ S S E+ ++ + E + S D +S +
Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 372
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 373 EAEEEVGEGTPQS 385
Score = 36.6 bits (83), Expect = 0.086
Identities = 48/230 (20%), Positives = 91/230 (39%), Gaps = 13/230 (5%)
Query: 378 KYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD 437
K+A +++K E ER+KR Q + + + E + + + E
Sbjct: 120 KHARVKEKEREHERRKRHREEQDKARREWERQKRR----EMAREHSRRERDRLEQLERKR 175
Query: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQE--GQEDDEEEDEEEEAAA---GKDG 492
E + + E+++E+ E++E E E ++ E +E ED ++ A +
Sbjct: 176 ERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 235
Query: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQP 552
+ P ++ + + +P K+ + + + +S S SS ++ S E+
Sbjct: 236 PRPPRERFELGDGR--KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 293
Query: 553 EELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLE 602
EE EEE S E E E + E S+S + SE+ V E
Sbjct: 294 EEEEEEEEEEGSTSEESEEE--EEEEEEEEEETGSNSEEASEQSAEEVSE 341
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/101 (35%), Positives = 59/101 (58%), Gaps = 8/101 (7%)
Query: 412 SLDSGEGPSGMASQGC-PSASRAETDDEDDEESDEEEEEEEEEEE----EEATDSEE--- 463
S+ GP+ +S+ S S +E DDE+DE+ ++E+EEEE++E E+ DS E
Sbjct: 618 SMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 677
Query: 464 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
E++ E E +EDDE+ED++E+ +D + SS S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Score = 43.5 bits (101), Expect = 7e-04
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 17/130 (13%)
Query: 374 EVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSAS-- 431
E IS K K R LQ S D E D E + S+
Sbjct: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669
Query: 432 --RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 489
+E+ ED+ E +E EE++E+E D +E++D ED++ E E +++
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDE-----DDDEDDD--------EDEDNESEGSSSSSS 716
Query: 490 KDGDKSPMSS 499
GD S S
Sbjct: 717 SSGDSSDSDS 726
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
Query: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
P +SR + + E D+EE+E++E+E+EE +EDDE D E+
Sbjct: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEE----------------EEDDENGDSSEDGG 670
Query: 488 AGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAES 547
+ S NE++ E ++ N+ S S S + S D++S
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS----SGDSSDSDS 726
Query: 548 N 548
N
Sbjct: 727 N 727
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 363 ENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGM 422
+ +S+ R S LQ KSE E + + D G S
Sbjct: 615 KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE 674
Query: 423 ASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS 461
+S S E +++D++E D+E+++E+E+ E E + S
Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSS 713
Score = 31.2 bits (69), Expect = 3.6
Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+D+ +E E ++ G SS D ++S S E S + + D++DDE+
Sbjct: 646 EDEDDEDEDEEEEDDENGDSSE--DGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDED 703
Query: 443 SDEEEEEEEEEEEEEATDSEEEED 466
D E E S+ + +
Sbjct: 704 EDNESEGSSSSSSSSGDSSDSDSN 727
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/101 (35%), Positives = 59/101 (58%), Gaps = 8/101 (7%)
Query: 412 SLDSGEGPSGMASQGC-PSASRAETDDEDDEESDEEEEEEEEEEE----EEATDSEE--- 463
S+ GP+ +S+ S S +E DDE+DE+ ++E+EEEE++E E+ DS E
Sbjct: 618 SMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 677
Query: 464 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
E++ E E +EDDE+ED++E+ +D + SS S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Score = 43.5 bits (101), Expect = 7e-04
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 17/130 (13%)
Query: 374 EVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSAS-- 431
E IS K K R LQ S D E D E + S+
Sbjct: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669
Query: 432 --RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 489
+E+ ED+ E +E EE++E+E D +E++D ED++ E E +++
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDE-----DDDEDDD--------EDEDNESEGSSSSSS 716
Query: 490 KDGDKSPMSS 499
GD S S
Sbjct: 717 SSGDSSDSDS 726
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
Query: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
P +SR + + E D+EE+E++E+E+EE +EDDE D E+
Sbjct: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEE----------------EEDDENGDSSEDGG 670
Query: 488 AGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAES 547
+ S NE++ E ++ N+ S S S + S D++S
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS----SGDSSDSDS 726
Query: 548 N 548
N
Sbjct: 727 N 727
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 363 ENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGM 422
+ +S+ R S LQ KSE E + + D G S
Sbjct: 615 KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE 674
Query: 423 ASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS 461
+S S E +++D++E D+E+++E+E+ E E + S
Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSS 713
Score = 31.2 bits (69), Expect = 3.6
Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+D+ +E E ++ G SS D ++S S E S + + D++DDE+
Sbjct: 646 EDEDDEDEDEEEEDDENGDSSE--DGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDED 703
Query: 443 SDEEEEEEEEEEEEEATDSEEEED 466
D E E S+ + +
Sbjct: 704 EDNESEGSSSSSSSSGDSSDSDSN 727
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/101 (35%), Positives = 59/101 (58%), Gaps = 8/101 (7%)
Query: 412 SLDSGEGPSGMASQGC-PSASRAETDDEDDEESDEEEEEEEEEEE----EEATDSEE--- 463
S+ GP+ +S+ S S +E DDE+DE+ ++E+EEEE++E E+ DS E
Sbjct: 655 SMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 714
Query: 464 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
E++ E E +EDDE+ED++E+ +D + SS S+
Sbjct: 715 EDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 755
Score = 43.5 bits (101), Expect = 7e-04
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 17/130 (13%)
Query: 374 EVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSAS-- 431
E IS K K R LQ S D E D E + S+
Sbjct: 647 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 706
Query: 432 --RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 489
+E+ ED+ E +E EE++E+E D +E++D ED++ E E +++
Sbjct: 707 GDSSESSSEDESEDGDENEEDDEDE-----DDDEDDD--------EDEDNESEGSSSSSS 753
Query: 490 KDGDKSPMSS 499
GD S S
Sbjct: 754 SSGDSSDSDS 763
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
Query: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
P +SR + + E D+EE+E++E+E+EE +EDDE D E+
Sbjct: 664 PKSSRTTLQSKSESEEDDEEDEDDEDEDEE----------------EEDDENGDSSEDGG 707
Query: 488 AGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAES 547
+ S NE++ E ++ N+ S S S + S D++S
Sbjct: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS----SGDSSDSDS 763
Query: 548 N 548
N
Sbjct: 764 N 764
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 363 ENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGM 422
+ +S+ R S LQ KSE E + + D G S
Sbjct: 652 KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE 711
Query: 423 ASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS 461
+S S E +++D++E D+E+++E+E+ E E + S
Sbjct: 712 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSS 750
Score = 31.2 bits (69), Expect = 3.6
Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEE 442
+D+ +E E ++ G SS D ++S S E S + + D++DDE+
Sbjct: 683 EDEDDEDEDEEEEDDENGDSSE--DGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDED 740
Query: 443 SDEEEEEEEEEEEEEATDSEEEED 466
D E E S+ + +
Sbjct: 741 EDNESEGSSSSSSSSGDSSDSDSN 764
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 61.2 bits (147), Expect = 3e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 293
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 294 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 339
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 340 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQ 395
Query: 558 E 558
E
Sbjct: 396 E 396
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/169 (28%), Positives = 66/169 (39%), Gaps = 26/169 (15%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
LQD S+ ERK A S S E + E G S+ S E ++E++E
Sbjct: 254 LQDISDS-ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE--ESEEEEEEEEEEEE 310
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG-----------QEDDEEEDEEEEAAAG- 489
E+ EE E+ EE ++ E ED E+ E ++ E E+ EEE G
Sbjct: 311 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 370
Query: 490 ------KDGDKSPMSSLQISNEKNLE-----PGKQISRSSGEQQNKGRI 527
+GD P S + E E P Q RS E Q RI
Sbjct: 371 PQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRI 419
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD----- 437
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 182 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240
Query: 438 --EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
E EE D + ++ + E T S E E +E++EEE+EEEE + + +
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300
Query: 496 PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE----PLAPSSIDAESNGEQ 551
+ E+ ++ S S E+ ++ + E + S D +S +
Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 360
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 361 EAEEEVGEGTPQS 373
Score = 35.8 bits (81), Expect = 0.15
Identities = 57/257 (22%), Positives = 92/257 (35%), Gaps = 29/257 (11%)
Query: 383 QDKSE-EGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
QDK+ E ER+KRR + S D E E M Q + E + +E
Sbjct: 129 QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEE 188
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLE----------------QMQEGQEDDEEEDEEEE 485
E E E + + ++ ++ +G++ +EE EE
Sbjct: 189 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 248
Query: 486 AAAGKDGDKS----PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 541
D S SS + S+ ++ ++ E++ +G S EE
Sbjct: 249 DLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 308
Query: 542 SIDAESNGEQPEELTLEE--ESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTT 599
+ SN E+ E + EE E +S+ E E E L P S S +++EE
Sbjct: 309 EEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE---- 364
Query: 600 VLENGAGMVSSTSFNGG 616
E G G S++ G
Sbjct: 365 --EVGEGTPQSSALTEG 379
Score = 30.0 bits (66), Expect = 8.1
Identities = 36/180 (20%), Positives = 74/180 (41%), Gaps = 22/180 (12%)
Query: 363 ENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGE-GPSG 421
E S + LDE++ + +++ E+ E K+ + +S D+ SL+ GE
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLK------NSDDRDSKRDSLEEGELRDHC 57
Query: 422 MASQGCPSASRAETDDEDDEESDEE------EEEEEEEEEEEATDSEEEEDLE--QMQEG 473
M S R E ED E D+ ++ +E+ D + +E + +++E
Sbjct: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKER 117
Query: 474 QEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEK-------NLEPGKQISRSSGEQQNKGR 526
+ + + EE+ A ++ ++ + + + LE ++ R EQQ + R
Sbjct: 118 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 177
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 61.2 bits (147), Expect = 3e-09
Identities = 54/181 (29%), Positives = 70/181 (38%), Gaps = 32/181 (17%)
Query: 385 KSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESD 444
K E+ E + + LQ S T A S E SG S E ++E++EE
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG-------SEEEEEEEEEEEEEGS 303
Query: 445 -----EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499
EEEEEEEEEEEEE + EE + +E E++ EDEE E
Sbjct: 304 TSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE-------------- 349
Query: 500 LQISNEKNL--EPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTL 557
NE +L P + R SGE + V L +S P EL
Sbjct: 350 ----NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQ 405
Query: 558 E 558
E
Sbjct: 406 E 406
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/169 (28%), Positives = 66/169 (39%), Gaps = 26/169 (15%)
Query: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
LQD S+ ERK A S S E + E G S+ S E ++E++E
Sbjct: 264 LQDISDS-ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE--ESEEEEEEEEEEEE 320
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEG-----------QEDDEEEDEEEEAAAG- 489
E+ EE E+ EE ++ E ED E+ E ++ E E+ EEE G
Sbjct: 321 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 380
Query: 490 ------KDGDKSPMSSLQISNEKNLE-----PGKQISRSSGEQQNKGRI 527
+GD P S + E E P Q RS E Q RI
Sbjct: 381 PQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRI 429
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 12/193 (6%)
Query: 383 QDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD----- 437
+++ E RK+R AR + S+H E D + S P R E D
Sbjct: 192 RERRAEERRKEREARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 250
Query: 438 --EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495
E EE D + ++ + E T S E E +E++EEE+EEEE + + +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310
Query: 496 PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE----PLAPSSIDAESNGEQ 551
+ E+ ++ S S E+ ++ + E + S D +S +
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 370
Query: 552 PEELTLEEESPVS 564
E + E +P S
Sbjct: 371 EAEEEVGEGTPQS 383
Score = 35.8 bits (81), Expect = 0.15
Identities = 57/257 (22%), Positives = 92/257 (35%), Gaps = 29/257 (11%)
Query: 383 QDKSE-EGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
QDK+ E ER+KRR + S D E E M Q + E + +E
Sbjct: 139 QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEE 198
Query: 442 ESDEEEEEEEEEEEEEATDSEEEEDLE----------------QMQEGQEDDEEEDEEEE 485
E E E + + ++ ++ +G++ +EE EE
Sbjct: 199 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 258
Query: 486 AAAGKDGDKS----PMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 541
D S SS + S+ ++ ++ E++ +G S EE
Sbjct: 259 DLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 318
Query: 542 SIDAESNGEQPEELTLEE--ESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTT 599
+ SN E+ E + EE E +S+ E E E L P S S +++EE
Sbjct: 319 EEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE---- 374
Query: 600 VLENGAGMVSSTSFNGG 616
E G G S++ G
Sbjct: 375 --EVGEGTPQSSALTEG 389
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 60.8 bits (146), Expect = 4e-09
Identities = 78/335 (23%), Positives = 139/335 (41%), Gaps = 42/335 (12%)
Query: 289 VLRAVEKAAARHSLGLPRQQL-QLMAQDAFRDVGIRLQE---RRHLDLIYNFGCHLTDDY 344
+L ++K + H+ P Q+ + M+Q++F + Q+ R+ L+ L +
Sbjct: 107 MLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEAS 166
Query: 345 RPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYA------MLQDKSEEGERKKRRARL 398
D + +A L + ++ R + +S+++ + ++K + + K R+
Sbjct: 167 AESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGER 226
Query: 399 QGTSSHSADTPEASLDSGEGPSGMAS-QGCPSAS-------RAETDDEDDEESDEEEEEE 450
+ SS A L G P+ Q PS + +T++E++EE +EEE++E
Sbjct: 227 R--SSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDE 284
Query: 451 EEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEP 510
EEE ++E S E L++ +E E+ EE D+ P + Q ++ LE
Sbjct: 285 EEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMM------DERPKTRSQ--EQEVLER 336
Query: 511 GKQISRSSGE---------QQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEES 561
G + +RS E QQ K + L EE SS + + P L E+
Sbjct: 337 GGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDR 396
Query: 562 PVSQLFELEIEALPLDTPSSVETDISSSRKQSEEP 596
+ L ALP T S ET K++ P
Sbjct: 397 KKASLV-----ALPEQTASEEETPPPLLTKEASSP 426
Score = 43.5 bits (101), Expect = 7e-04
Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 9/98 (9%)
Query: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 489
A RAE E ++ E+EEEE++E E+EA + E LE+ ++ +E E D E E
Sbjct: 1239 AERAERAKEREKRRKEQEEEEQKEREKEA-ERERNRQLER-EKRREHSRERDRERERERE 1296
Query: 490 KD-GDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGR 526
+D GD+ E++ E G++ R ++ ++ R
Sbjct: 1297 RDRGDRDR------DRERDRERGRERDRRDTKRHSRSR 1328
Score = 35.4 bits (80), Expect = 0.19
Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 16/174 (9%)
Query: 388 EGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEE 447
EG + R+ R +++ + P S+ + E + P A + D ++S E
Sbjct: 841 EGGQPGRKRRWGASTATTQKKPSISITT-ESLKSLIPDIKPLAGQEAVVDLHADDSRISE 899
Query: 448 EEEEEEEEEEATDSEEEEDLEQMQ----EGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS 503
+E E ++ D + Q EGQE+ + E+EEEE + P S++++
Sbjct: 900 DETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVA 959
Query: 504 -------NEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGE 550
K + G ++R S QQ G S+ ++P+ + + + G+
Sbjct: 960 LPPPAEHEVKKVTLGDTLTRRSISQQKSG----VSITIDDPVRTAQVPSPPRGK 1009
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/67 (26%), Positives = 29/67 (43%)
Query: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
P RAE +++ ++ E E E E E T SE E D ++++EG +
Sbjct: 1128 PQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKE 1187
Query: 488 AGKDGDK 494
K +K
Sbjct: 1188 RAKSKEK 1194
Score = 32.0 bits (71), Expect = 2.1
Identities = 15/67 (22%), Positives = 38/67 (56%)
Query: 455 EEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQI 514
++EA +E ++ E+ ++ QE++E+++ E+EA ++ + S E++ E ++
Sbjct: 1236 QKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERER 1295
Query: 515 SRSSGEQ 521
R G++
Sbjct: 1296 ERDRGDR 1302
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 60.5 bits (145), Expect = 6e-09
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 410 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469
E ++S G + + S +ET++E ++ESDEE EE+ EEE E+ +SE EED
Sbjct: 88 EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEED--- 144
Query: 470 MQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVS 529
QE+ E E E E A + + M + +++ K + G +S E + ++
Sbjct: 145 ---NQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLC 201
Query: 530 PSLLSEEPLAPSSID 544
P + + + S++D
Sbjct: 202 PVIGAHQGHQLSTLD 216
Score = 55.1 bits (131), Expect = 2e-07
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE-DEEEEAAAGK 490
+ E + E + E+ EE E EEE E EE +++EEE + E +E +ED EEE ++E+E+ A +
Sbjct: 84 KVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEE 143
Query: 491 DGDKSPMSSLQISNEKNLE 509
D + S + E E
Sbjct: 144 DNQEEGESEAEGETEAESE 162
Score = 50.8 bits (120), Expect = 4e-06
Identities = 39/109 (35%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Query: 408 TPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEE-E-----EEEEEEATDS 461
TP A GEG +G E + E EES+ EEE E E EEE E+ +D
Sbjct: 68 TPPAD---GEG-AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDE 123
Query: 462 EEEEDL-EQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLE 509
E EED E+M++ QE + EED +EE + +G+ S E E
Sbjct: 124 ESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 12/94 (12%)
Query: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE-EEDEEEEAAA 488
A + E + + ++E + E E EE E EE ++SEEE + E+ E + D+E EED EEE
Sbjct: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
Query: 489 GKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQ 522
++ + + E N E G+ S + GE +
Sbjct: 136 EQESE---------AEEDNQEEGE--SEAEGETE 158
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 6/108 (5%)
Query: 387 EEGERKKRRAR-LQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE 445
EE E K + R ++ + +++ E S E + S+ S E++++ +EE ++
Sbjct: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE---DESDEESEEDSEEEMED 135
Query: 446 EEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGD 493
E+E E EE+ +E +SE E + E E + D E E E E A K D
Sbjct: 136 EQESEAEEDNQEEGESEAEGETE--AESEFDPEIEMEAERVAKRKCPD 181
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
Query: 431 SRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGK 490
S+A T D E + +EE E + E+E E E E E E + + EEE E EE + +
Sbjct: 64 SQAWTPPADGEGAGKEEAEVKVEQEREI---ESEAGEESESEEESESEEESETEEESEDE 120
Query: 491 DGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEE 536
++S S + ++ ++ ++ GE + +G + S E
Sbjct: 121 SDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,627,803
Number of Sequences: 37866
Number of extensions: 1905183
Number of successful extensions: 76651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1224
Number of HSP's successfully gapped in prelim test: 1029
Number of HSP's that attempted gapping in prelim test: 19210
Number of HSP's gapped (non-prelim): 19293
length of query: 740
length of database: 18,247,518
effective HSP length: 110
effective length of query: 630
effective length of database: 14,082,258
effective search space: 8871822540
effective search space used: 8871822540
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.