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Search of human proteins with 4503063
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503063 crystallin, beta B2 [Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503063 crystallin, beta B2 [Homo sapiens] 436 e-123
gi|4758074 crystallin, beta B3 [Homo sapiens] 246 1e-65
gi|4503061 crystallin, beta B1 [Homo sapiens] 239 1e-63
gi|12056461 crystallin, beta A3 [Homo sapiens] 166 1e-41
gi|4503059 crystallin, beta A4 [Homo sapiens] 150 7e-37
gi|16936542 crystallin, beta A2 [Homo sapiens] 134 4e-32
gi|16936540 crystallin, beta A2 [Homo sapiens] 134 4e-32
gi|7019357 crystallin, beta A2 [Homo sapiens] 134 4e-32
gi|8922120 crystallin, gamma S [Homo sapiens] 118 3e-27
gi|148491074 crystallin, gamma B [Homo sapiens] 118 4e-27
gi|10518338 crystallin, gamma C [Homo sapiens] 114 6e-26
gi|89886227 absent in melanoma 1-like [Homo sapiens] 111 4e-25
gi|148491057 crystallin, gamma A [Homo sapiens] 110 8e-25
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi... 106 2e-23
gi|62988361 absent in melanoma 1 [Homo sapiens] 105 3e-23
gi|13377002 crystallin, gamma D [Homo sapiens] 103 1e-22
gi|21389517 gammaN-crystallin [Homo sapiens] 81 7e-16
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 28 5.5
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 28 5.5
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 28 5.5
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 28 5.5
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 28 7.1
gi|38570064 hypothetical protein LOC136895 [Homo sapiens] 28 7.1
gi|95147333 phospholipase C, beta 2 [Homo sapiens] 27 9.3
gi|115527120 nebulin [Homo sapiens] 27 9.3
gi|122114658 hypothetical protein LOC23053 [Homo sapiens] 27 9.3
>gi|4503063 crystallin, beta B2 [Homo sapiens]
Length = 205
Score = 436 bits (1120), Expect = e-123
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV 60
MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
Sbjct: 1 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV 60
Query: 61 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK 120
GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
Sbjct: 61 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK 120
Query: 121 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP 180
KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
Sbjct: 121 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP 180
Query: 181 HPQVQSVRRIRDMQWHQRGAFHPSN 205
HPQVQSVRRIRDMQWHQRGAFHPSN
Sbjct: 181 HPQVQSVRRIRDMQWHQRGAFHPSN 205
>gi|4758074 crystallin, beta B3 [Homo sapiens]
Length = 211
Score = 246 bits (628), Expect = 1e-65
Identities = 106/187 (56%), Positives = 149/187 (79%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
K+I++E ENFQG EL+ CP+L ++ +EK GS+ V++GPW+ +E +GEQFV EKG
Sbjct: 25 KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137
+YPRWD+W++SR +DSL SLRP+ +DS HK+ L+ENP F+G+KMEI+DDDVPS AHG+
Sbjct: 85 DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144
Query: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQ 197
Q++V+SVR +GTWVGY++PGYRG QY+ E+G+Y+ +++ A PQ+QSVRRIRD +WH+
Sbjct: 145 QDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHK 204
Query: 198 RGAFHPS 204
RG F S
Sbjct: 205 RGRFPSS 211
Score = 58.9 bits (141), Expect = 3e-09
Identities = 29/65 (44%), Positives = 43/65 (66%), Gaps = 2/65 (3%)
Query: 107 HKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLL 166
+K+ILYE NF GK+ E + + PS EKV S++V+SG W+ ++ +RG Q++L
Sbjct: 24 YKVILYELENFQGKRCE-LSAECPSL-TDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
Query: 167 EKGDY 171
EKGDY
Sbjct: 82 EKGDY 86
>gi|4503061 crystallin, beta B1 [Homo sapiens]
Length = 252
Score = 239 bits (610), Expect = 1e-63
Identities = 104/186 (55%), Positives = 140/186 (75%)
Query: 16 NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFE 75
N ++++FE ENFQG E +G C NL + G ++ S++V AGPWV +EQ+N +GE F+ E
Sbjct: 58 NYRLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILE 117
Query: 76 KGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAH 135
KGEYPRW++W+SS R+D L S RPIK+D+QEHKI L+E NF G +EI DD PS +
Sbjct: 118 KGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVY 177
Query: 136 GYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDMQW 195
G+ ++V SV+V SGTWVGYQYPGYRG QYLLE GD++ +++GA PQ+QS+RR+RD QW
Sbjct: 178 GFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQW 237
Query: 196 HQRGAF 201
H G+F
Sbjct: 238 HLEGSF 243
>gi|12056461 crystallin, beta A3 [Homo sapiens]
Length = 215
Score = 166 bits (421), Expect = 1e-41
Identities = 88/191 (46%), Positives = 121/191 (63%), Gaps = 12/191 (6%)
Query: 12 PQSLNP-KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGE 70
P SL P KI I++QENFQG E CPN+ E + S+ V++G W+GYE + G+
Sbjct: 25 PGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQ 84
Query: 71 QFVFEKGEYPRWDSWTSSR--RTDSLSSLRPI-KVDSQEHKIILYENPNFTGKKMEIIDD 127
QF+ E+GEYPRWD+W+ S + L S RPI + +E K+ ++E NF G++ E I D
Sbjct: 85 QFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWE-ISD 143
Query: 128 DVPSFHAHG-YQEKVSSVRVQSGTWVGYQYPGYRGLQYLLE----KGDYKDSSDFG--AP 180
D PS A G + +V S+++QSG WV YQYPGYRG QY+LE GDYK ++G A
Sbjct: 144 DYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQ 203
Query: 181 HPQVQSVRRIR 191
Q+QS+RRI+
Sbjct: 204 TSQIQSIRRIQ 214
Score = 55.8 bits (133), Expect = 2e-08
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 91 TDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGT 150
T ++ P KI +Y+ NF GK+ME P+ + + V S++V+SG
Sbjct: 15 TTKMAQTNPTPGSLGPWKITIYDQENFQGKRME-FTSSCPNVSERSF-DNVRSLKVESGA 72
Query: 151 WVGYQYPGYRGLQYLLEKGDY 171
W+GY++ + G Q++LE+G+Y
Sbjct: 73 WIGYEHTSFCGQQFILERGEY 93
>gi|4503059 crystallin, beta A4 [Homo sapiens]
Length = 196
Score = 150 bits (379), Expect = 7e-37
Identities = 77/184 (41%), Positives = 116/184 (63%), Gaps = 11/184 (5%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
K+++++++ FQG HE CP++ E G E S+ V +G WVG+E A +G+Q++ E+G
Sbjct: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72
Query: 78 EYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKMEIIDDDVPSFHA 134
EYP WD+W ++ + L+S RP + ++ ++ ++E NF GKK E + DD PS A
Sbjct: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGE-LSDDYPSLQA 131
Query: 135 HGYQ-EKVSSVRVQSGTWVGYQYPGYRGLQYLLE----KGDYKDSSDFG--APHPQVQSV 187
G++ +V S V SG WV Q+PGYRG QY+LE GDYK ++G AP QVQS+
Sbjct: 132 MGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSI 191
Query: 188 RRIR 191
RRI+
Sbjct: 192 RRIQ 195
>gi|16936542 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 134 bits (338), Expect = 4e-32
Identities = 74/196 (37%), Positives = 117/196 (59%), Gaps = 12/196 (6%)
Query: 7 TQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQA 65
+ A P + ++++E+FQG L C N+ E G + + SV V+ G WV +E
Sbjct: 2 SSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYP 61
Query: 66 NCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKM 122
+ +G+QF+ EKG+YPRW +W +SS ++ L S RP+ + + ++ L+E NF G K
Sbjct: 62 DFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKF 121
Query: 123 EIIDDDVPSFHAHGYQEK-VSSVRVQSGTWVGYQYPGYRGLQYLLEK----GDYKDSSDF 177
+++ DD PS + G+ K V S++V SG WV YQYPGYRG QY+LE+ G++ +
Sbjct: 122 DLV-DDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
Query: 178 G--APHPQVQSVRRIR 191
G A Q+QS+RR++
Sbjct: 181 GTQAHTGQLQSIRRVQ 196
>gi|16936540 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 134 bits (338), Expect = 4e-32
Identities = 74/196 (37%), Positives = 117/196 (59%), Gaps = 12/196 (6%)
Query: 7 TQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQA 65
+ A P + ++++E+FQG L C N+ E G + + SV V+ G WV +E
Sbjct: 2 SSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYP 61
Query: 66 NCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKM 122
+ +G+QF+ EKG+YPRW +W +SS ++ L S RP+ + + ++ L+E NF G K
Sbjct: 62 DFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKF 121
Query: 123 EIIDDDVPSFHAHGYQEK-VSSVRVQSGTWVGYQYPGYRGLQYLLEK----GDYKDSSDF 177
+++ DD PS + G+ K V S++V SG WV YQYPGYRG QY+LE+ G++ +
Sbjct: 122 DLV-DDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
Query: 178 G--APHPQVQSVRRIR 191
G A Q+QS+RR++
Sbjct: 181 GTQAHTGQLQSIRRVQ 196
>gi|7019357 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 134 bits (338), Expect = 4e-32
Identities = 74/196 (37%), Positives = 117/196 (59%), Gaps = 12/196 (6%)
Query: 7 TQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQA 65
+ A P + ++++E+FQG L C N+ E G + + SV V+ G WV +E
Sbjct: 2 SSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYP 61
Query: 66 NCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKM 122
+ +G+QF+ EKG+YPRW +W +SS ++ L S RP+ + + ++ L+E NF G K
Sbjct: 62 DFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKF 121
Query: 123 EIIDDDVPSFHAHGYQEK-VSSVRVQSGTWVGYQYPGYRGLQYLLEK----GDYKDSSDF 177
+++ DD PS + G+ K V S++V SG WV YQYPGYRG QY+LE+ G++ +
Sbjct: 122 DLV-DDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
Query: 178 G--APHPQVQSVRRIR 191
G A Q+QS+RR++
Sbjct: 181 GTQAHTGQLQSIRRVQ 196
>gi|8922120 crystallin, gamma S [Homo sapiens]
Length = 178
Score = 118 bits (296), Expect = 3e-27
Identities = 62/174 (35%), Positives = 97/174 (55%), Gaps = 5/174 (2%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
KI +E +NFQG ++ + C + T + + S+ V+ G W YE+ N G ++ +G
Sbjct: 7 KITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQ-EHKIILYENPNFTGKKMEIIDDDVPSFHAHG 136
EYP + W D LSS R + + S ++KI ++E +F+G+ E +D PS
Sbjct: 66 EYPEYQRWMGLN--DRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTED-CPSIMEQF 122
Query: 137 YQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRI 190
+ ++ S +V G W+ Y+ P YRG QYLL+K +Y+ D+GA P VQS RRI
Sbjct: 123 HMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI 176
>gi|148491074 crystallin, gamma B [Homo sapiens]
Length = 175
Score = 118 bits (295), Expect = 4e-27
Identities = 61/176 (34%), Positives = 99/176 (56%), Gaps = 4/176 (2%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
KI +E FQG S+E CPNL+ + S+ V++G W+ YE+ N +G Q+ +G
Sbjct: 3 KITFYEDRAFQGRSYECTTDCPNLQPY-FSRCNSIRVESGCWMIYERPNYQGHQYFLRRG 61
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137
EYP + W +DS+ S I S +++ +Y+ G+ E+ DD + S +
Sbjct: 62 EYPDYQQWMGL--SDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCI-SVQDRFH 118
Query: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDM 193
++ S+ V G+W+ Y+ P YRG QYLL G+Y+ D+GAP+ +V S+RR+ D+
Sbjct: 119 LTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDL 174
>gi|10518338 crystallin, gamma C [Homo sapiens]
Length = 174
Score = 114 bits (285), Expect = 6e-26
Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 5/176 (2%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
KI +E FQG S+E CPNL+ + S+ V++G W+ YE+ N +G+Q++ +G
Sbjct: 3 KITFYEDRAFQGRSYETTTDCPNLQPY-FSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137
EYP + W +DS+ S I + H++ LYE + G ME+ +D PS +
Sbjct: 62 EYPDYQQWMGL--SDSIRSCCLIP-QTVSHRLRLYEREDHKGLMMEL-SEDCPSIQDRFH 117
Query: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDM 193
++ S+ V G WV Y+ P YRG QYLL +Y+ D+GA + S+RR+ D+
Sbjct: 118 LSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDL 173
Score = 47.8 bits (112), Expect = 7e-06
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 12 PQSLNPKIIIFEQENFQGHSHELNGPCPNLKET-GVEKAGSVLVQAGPWVGYEQANCKGE 70
PQ+++ ++ ++E+E+ +G EL+ CP++++ + + S+ V G WV YE N +G
Sbjct: 83 PQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGR 142
Query: 71 QFVFEKGEYPRWDSW 85
Q++ EY R W
Sbjct: 143 QYLLRPQEYRRCQDW 157
>gi|89886227 absent in melanoma 1-like [Homo sapiens]
Length = 616
Score = 111 bits (278), Expect = 4e-25
Identities = 60/186 (32%), Positives = 100/186 (53%), Gaps = 9/186 (4%)
Query: 17 PKIIIFEQENFQGHSHELNGPCPNLKETG------VEKAGSVLVQAGPWVGYEQANCKGE 70
P+ +++E FQG S E++ NL++ + GS+ V G WVGYE+ +G
Sbjct: 123 PRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGH 182
Query: 71 QFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVP 130
Q++ E+GEYP W W + L+SLR I+ D + ++L+E +F G +E+ +P
Sbjct: 183 QYLLEEGEYPDWSHWGGY--DELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEV-SKALP 239
Query: 131 SFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRI 190
+ ++ V SG WV YQ G+ G QY+LEKG Y++ D+GA + + S++ +
Sbjct: 240 DVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPV 299
Query: 191 RDMQWH 196
+ H
Sbjct: 300 LQVGEH 305
Score = 96.7 bits (239), Expect = 1e-20
Identities = 62/188 (32%), Positives = 96/188 (51%), Gaps = 17/188 (9%)
Query: 17 PKIIIFEQENFQGHSHELNGPCPNLKETGVEK---AGSVLVQAGPWVGYEQANCKGEQFV 73
P+I +F +E +G +L N + G+EK S V AG W+ Y + + ++
Sbjct: 28 PEISLFSEEGLKGEQVKLTEALKNSQ--GLEKPLQVASATVSAGLWLLYPKPLFEDTPYI 85
Query: 74 FEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ------EHKIILYENPNFTGKKMEIIDD 127
E GEYP ++W +S S+ SL+P+++ E + ++YE P F G+ E+ D
Sbjct: 86 LEPGEYPTSEAWGTS--DPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRD 143
Query: 128 ----DVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQ 183
P + V S+RV G WVGY+ G+RG QYLLE+G+Y D S +G
Sbjct: 144 IYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDEL 203
Query: 184 VQSVRRIR 191
+ S+R IR
Sbjct: 204 LTSLRVIR 211
Score = 78.6 bits (192), Expect = 4e-15
Identities = 50/171 (29%), Positives = 85/171 (49%), Gaps = 16/171 (9%)
Query: 16 NPKIIIFEQENFQGHSHELNGPCPN--LKETGVEKAGSVLVQAGPWVGYEQANCKGEQFV 73
+P +++FE +F+GH E++ P+ L + G ++ V +G WV Y++ GEQ+V
Sbjct: 216 DPAVVLFEAMDFEGHGVEVSKALPDVELVQHG-PSTQAIHVLSGVWVAYQEVGFSGEQYV 274
Query: 74 FEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEH------KIILYENPNFTGKKMEIIDD 127
EKG Y + W + T L+SL+P+ + EH KI L+ P+F G DD
Sbjct: 275 LEKGVYRNCEDWGAGNST--LASLQPV-LQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDD 331
Query: 128 DVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFG 178
A + S RV G+W+ + + G Q++L +G++ + G
Sbjct: 332 QA----ALPASFRPQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMG 378
Score = 67.0 bits (162), Expect = 1e-11
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 10/152 (6%)
Query: 51 SVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKII 110
S V G W+ +++ N +G+Q + +GE+P + T L SL+ + + E I
Sbjct: 343 SCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLAST-VLGSLQKVSLHFSEPSIF 401
Query: 111 LYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGD 170
LY F GK++E+ +V S A G+ V SVR++ G WV ++ +RG Q+L+ +
Sbjct: 402 LYGLECFEGKEIEL-SREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCE 460
Query: 171 ------YKDSSDFGAPHPQVQSVRRIRDMQWH 196
Y + G+ +P Q RR+ W+
Sbjct: 461 ITNWLTYSGTQRVGSLYPIKQ--RRVYFRLWN 490
>gi|148491057 crystallin, gamma A [Homo sapiens]
Length = 174
Score = 110 bits (275), Expect = 8e-25
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
KI +E +FQG + CPNL+ + S+ V +G W+ YE+ N +G Q+ +G
Sbjct: 3 KITFYEDRDFQGRCYNCISDCPNLR-VYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDD--VPSFHAH 135
+YP + W +DS+ S R I S HK+ LYE ++ G E+ DD VP
Sbjct: 62 KYPDYQHWMGL--SDSVQSCRIIPHTSS-HKLRLYERDDYRGLMSELTDDCACVPELFR- 117
Query: 136 GYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDM 193
++ S+ V G WV Y+ P YRG QYLL GDY+ D+G +V S+RR+ D+
Sbjct: 118 --LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDL 173
Score = 54.3 bits (129), Expect = 7e-08
Identities = 32/90 (35%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Query: 108 KIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLE 167
KI YE+ +F G+ I D P+ Y + +S+RV SG W+ Y+ P Y+G QY L
Sbjct: 3 KITFYEDRDFQGRCYNCISD-CPNLRV--YFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
Query: 168 KGDYKDSSDFGAPHPQVQSVRRIRDMQWHQ 197
+G Y D + VQS R I H+
Sbjct: 60 RGKYPDYQHWMGLSDSVQSCRIIPHTSSHK 89
>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
sapiens]
Length = 1022
Score = 106 bits (264), Expect = 2e-23
Identities = 66/199 (33%), Positives = 106/199 (53%), Gaps = 10/199 (5%)
Query: 1 MASDHQTQAGK---PQSLNPKIIIFEQENFQGHSHELN---GPCPN-LKETG-VEKAGSV 52
M S H Q G +N K+II+E+ +F G + E + PN LK G + GS+
Sbjct: 512 MKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSI 571
Query: 53 LVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILY 112
V G WV YE+ + KG+QF+ E+G++ DS + + S R ++ + E + L+
Sbjct: 572 RVIGGVWVAYEKEHFKGQQFLLEEGDFE--DSNACGALSSPILSFRYLQANFIESSVTLF 629
Query: 113 ENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYK 172
E+ +GK ++I + ++ G+ K S+ V+SG WV YQ + G QY+LEKG YK
Sbjct: 630 ESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYK 689
Query: 173 DSSDFGAPHPQVQSVRRIR 191
D+G + + S+R I+
Sbjct: 690 CFFDWGGSNNIIMSIRPIQ 708
Score = 90.1 bits (222), Expect = 1e-18
Identities = 57/184 (30%), Positives = 94/184 (51%), Gaps = 15/184 (8%)
Query: 17 PKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEK 76
P+I +F Q + + PNL+E + K+ S V++G W+ Y N KG+ V E+
Sbjct: 441 PEIELFPQSDPACCPVYIQRAVPNLEELNISKSVSFTVKSGVWLAYPDINFKGQATVLEE 500
Query: 77 GEYPRWDSWTSSRRTDSLSSLRPIKVDS------QEHKIILYENPNFTGKKMEIID--DD 128
D T + SL P+++ K+I+YE P+F G+ E + D
Sbjct: 501 ------DHGLFEISTAEMKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDS 554
Query: 129 VPSF-HAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSV 187
VP+F +G ++ S+RV G WV Y+ ++G Q+LLE+GD++DS+ GA + S
Sbjct: 555 VPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNACGALSSPILSF 614
Query: 188 RRIR 191
R ++
Sbjct: 615 RYLQ 618
Score = 64.3 bits (155), Expect = 7e-11
Identities = 49/185 (26%), Positives = 87/185 (47%), Gaps = 18/185 (9%)
Query: 15 LNPKIIIFEQENFQGHSHEL-NGPCPNLKETGV-EKAGSVLVQAGPWVGYEQANCKGEQF 72
+ + +FE + G ++ N +L+E G K S+ V++G WV Y+Q GEQ+
Sbjct: 622 IESSVTLFESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQY 681
Query: 73 VFEKGEYPRWDSWTSSRRTDSLSSLRPIK-----VDSQEHKIILYENPNFTGKKMEIIDD 127
+ EKG+Y + W S + S+RPI+ ++ H + + P F G+ ++ ++
Sbjct: 682 ILEKGKYKCFFDWGGSNNI--IMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEE 739
Query: 128 --DVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQ 185
D+ S S +V G W+ Y +LE+G Y D + G P +V+
Sbjct: 740 TSDLTSLMP-------CSFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGCPASKVK 792
Query: 186 SVRRI 190
S++ I
Sbjct: 793 SLKPI 797
Score = 43.1 bits (100), Expect = 2e-04
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 17 PKIIIFEQENFQGHSHELNGPCPNLKETGVE-KAGSVLVQAGPWVGYEQANCKGEQFVFE 75
P I +F E+ +G L ++ + SV V++G W+ YE +N G Q +
Sbjct: 804 PSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLR 863
Query: 76 KGEYPRWDSWTSSRRTDSLSSLRPIK 101
E P +WT+ R ++ SLRP+K
Sbjct: 864 PNEIP---NWTAFSRWKTIGSLRPMK 886
Score = 40.0 bits (92), Expect = 0.001
Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 51 SVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKII 110
S V G W+ Y Q + V E+G Y D + + SL+PI +E I
Sbjct: 750 SFKVLRGCWLLYYQEDMFVNHCVLEEGLYA--DLTSCGCPASKVKSLKPIDYVFEEPSIS 807
Query: 111 LYENPNFTGKKMEIID--DDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEK 168
L+ + G+++ + + + V + H Y + SV V+SG W+ Y+ + G Q LL
Sbjct: 808 LFALEHCEGRELHLEEAVNSVLNKDLHFYTQ---SVWVKSGLWIAYEGSNFLGRQILLRP 864
Query: 169 GDYKDSSDF 177
+ + + F
Sbjct: 865 NEIPNWTAF 873
Score = 35.4 bits (80), Expect = 0.034
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 7/122 (5%)
Query: 52 VLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDS-----LSSLRPIKVDSQE 106
+ V G W+ YE+ + +G++ V E+GE W R L SL+ + D
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSI 440
Query: 107 HKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLL 166
+I L+ + + I VP+ + V S V+SG W+ Y ++G +L
Sbjct: 441 PEIELFPQSDPACCPV-YIQRAVPNLEELNISKSV-SFTVKSGVWLAYPDINFKGQATVL 498
Query: 167 EK 168
E+
Sbjct: 499 EE 500
Score = 29.6 bits (65), Expect = 1.9
Identities = 14/43 (32%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 144 VRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDF---GAPHPQ 183
++V G W+ Y+ P +RG + +LE+G+ + D+ HPQ
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQ 423
>gi|62988361 absent in melanoma 1 [Homo sapiens]
Length = 1723
Score = 105 bits (262), Expect = 3e-23
Identities = 66/189 (34%), Positives = 95/189 (50%), Gaps = 16/189 (8%)
Query: 16 NPKIIIFEQENFQGHSHELN-GPCPNLKETG-VEKA-----------GSVLVQAGPWVGY 62
+PK++++E+ F+G EL G C + E G E+A GS+ V G WV Y
Sbjct: 1217 DPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAY 1276
Query: 63 EQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKM 122
E+ G Q++ E+GEY W +W L SLRPI D +I+Y NF K
Sbjct: 1277 EKPGFTGHQYLLEEGEYRDWKAWGGYN--GELQSLRPILGDFSNAHMIMYSEKNFGSKGS 1334
Query: 123 EI-IDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPH 181
I + V + GY K S+ V SG WV Y+ P + G QY+L+KG Y D+G +
Sbjct: 1335 SIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKN 1394
Query: 182 PQVQSVRRI 190
++ SV+ I
Sbjct: 1395 CKISSVQPI 1403
Score = 89.7 bits (221), Expect = 2e-18
Identities = 53/163 (32%), Positives = 88/163 (53%), Gaps = 21/163 (12%)
Query: 46 VEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ 105
++K S+ V G W+ YE+ +G F+ E GEYP W + + S+RP+K+ +
Sbjct: 1153 MQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAY--IGSMRPLKMGGR 1210
Query: 106 ------EHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEK------------VSSVRVQ 147
+ K+++YE P F GK +E+ + + SF G + + V S++V
Sbjct: 1211 KVEFPTDPKVVVYEKPFFEGKCVEL-ETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVL 1269
Query: 148 SGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRI 190
G WV Y+ PG+ G QYLLE+G+Y+D +G + ++QS+R I
Sbjct: 1270 RGIWVAYEKPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPI 1312
Score = 89.0 bits (219), Expect = 3e-18
Identities = 57/171 (33%), Positives = 87/171 (50%), Gaps = 5/171 (2%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
+I +F + FQGHS + ++ K S V G WV Y+ N G Q+V E+G
Sbjct: 1416 QIHLFSEPQFQGHSQSFEETTSQIDDSFSTK--SCRVSGGSWVVYDGENFTGNQYVLEEG 1473
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137
YP + + SLR I V+ E IIL+E +F GKK+E+ + V + + G+
Sbjct: 1474 HYPCLSAMGCPPGA-TFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETV-NLRSLGF 1531
Query: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVR 188
++ SV+V G WV Y+Y YRG Q+LL + + +F Q+ S+R
Sbjct: 1532 NTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGCR-QIGSLR 1581
Score = 88.6 bits (218), Expect = 3e-18
Identities = 60/190 (31%), Positives = 96/190 (50%), Gaps = 14/190 (7%)
Query: 16 NPKIIIFEQENF--QGHSHELNGPCPNLKETGVE-KAGSVLVQAGPWVGYEQANCKGEQF 72
N +I++ ++NF +G S ++ G NLKETG K S+ V +G WV YE + GEQ+
Sbjct: 1318 NAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQY 1377
Query: 73 VFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDS-----QEHKIILYENPNFTGKKMEIIDD 127
+ +KG Y ++ W + +SS++PI +DS + ++I L+ P F G +
Sbjct: 1378 ILDKGFYTSFEDWGG--KNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHSQSF--E 1433
Query: 128 DVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSV 187
+ S + K S RV G+WV Y + G QY+LE+G Y S G P
Sbjct: 1434 ETTSQIDDSFSTK--SCRVSGGSWVVYDGENFTGNQYVLEEGHYPCLSAMGCPPGATFKS 1491
Query: 188 RRIRDMQWHQ 197
R D+++ +
Sbjct: 1492 LRFIDVEFSE 1501
Score = 72.0 bits (175), Expect = 3e-13
Identities = 53/204 (25%), Positives = 87/204 (42%), Gaps = 16/204 (7%)
Query: 3 SDHQTQAGKPQS-LNP---KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGP 58
SD T G Q+ LNP K++I+ + + E+ + + + V G
Sbjct: 1004 SDTMTLRGSVQNKLNPRPGKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGC 1063
Query: 59 WVGYEQANCKGEQFVFEKGEYPRWDSWTSS---RRTDSLSSLRPIKVDSQEH-------- 107
W+ YEQ N +G E+GE W R + S +P+ + S H
Sbjct: 1064 WILYEQPNFEGHSIPLEEGELELSGLWGIEDILERHEEAESDKPVVIGSIRHVVQDYRVS 1123
Query: 108 KIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLE 167
I L+ P G DD G +K S++V GTW+ Y+ PG++G+ ++LE
Sbjct: 1124 HIDLFTEPEGLGILSSYFDD-TEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILE 1182
Query: 168 KGDYKDSSDFGAPHPQVQSVRRIR 191
G+Y D S + + S+R ++
Sbjct: 1183 PGEYPDLSFWDTEAAYIGSMRPLK 1206
Score = 59.3 bits (142), Expect = 2e-09
Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 17 PKIIIFEQENFQGHSHELNGPCPNLKETGVE-KAGSVLVQAGPWVGYEQANCKGEQFVFE 75
P II+FE+E+F+G ELN NL+ G + SV V G WV YE + +G QF+
Sbjct: 1502 PTIILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLS 1561
Query: 76 KGEYPRWDSWTSSRRTDSLSSLRP 99
E P W ++ R+ + SLRP
Sbjct: 1562 PAEVPNWYEFSGCRQ---IGSLRP 1582
>gi|13377002 crystallin, gamma D [Homo sapiens]
Length = 174
Score = 103 bits (256), Expect = 1e-22
Identities = 62/175 (35%), Positives = 93/175 (53%), Gaps = 5/175 (2%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
KI ++E FQG +E + PNL+ + + S V +G W+ YEQ N G Q+ +G
Sbjct: 3 KITLYEDRGFQGRHYECSSDHPNLQPY-LSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61
Query: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137
+Y W +DS+ S R I S H+I LYE ++ G+ +E +D +
Sbjct: 62 DYADHQQWMGL--SDSVRSCRLIP-HSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRF 118
Query: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRD 192
E + S+ V G+WV Y+ YRG QYLL GDY+ D+GA + +V S+RR+ D
Sbjct: 119 NE-IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172
Score = 46.2 bits (108), Expect = 2e-05
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Query: 12 PQSLNPKIIIFEQENFQGHSHELNGPCPNLKET-GVEKAGSVLVQAGPWVGYEQANCKGE 70
P S + +I ++E+E+++G E C L++ + S+ V G WV YE +N +G
Sbjct: 83 PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGR 142
Query: 71 QFVFEKGEYPRWDSW-TSSRRTDSL 94
Q++ G+Y R+ W ++ R SL
Sbjct: 143 QYLLMPGDYRRYQDWGATNARVGSL 167
>gi|21389517 gammaN-crystallin [Homo sapiens]
Length = 182
Score = 80.9 bits (198), Expect = 7e-16
Identities = 39/131 (29%), Positives = 78/131 (59%), Gaps = 5/131 (3%)
Query: 18 KIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQANCKGEQFVFEK 76
KI ++E ++F G E+ G C N ++ G + + S+ V++G WV + + +G+QF+ E
Sbjct: 7 KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
Query: 77 GEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHG 136
G+YP + W S +D + S RP+ + + ++ ++E NFTG+ +E ++D P + G
Sbjct: 67 GDYPDFFRWNS--HSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDS-PFLQSRG 123
Query: 137 YQEK-VSSVRV 146
+ + V++++V
Sbjct: 124 WVKNCVNTIKV 134
Score = 69.7 bits (169), Expect = 2e-12
Identities = 30/66 (45%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Query: 108 KIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLE 167
KI LYE +FTG+K+E+ D +F G+ +V+S+ V+SG WV + +P +RG Q++LE
Sbjct: 7 KITLYEGKHFTGQKLEVFGD-CDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
Query: 168 KGDYKD 173
GDY D
Sbjct: 66 HGDYPD 71
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 28.1 bits (61), Expect = 5.5
Identities = 33/155 (21%), Positives = 56/155 (36%), Gaps = 23/155 (14%)
Query: 8 QAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANC 67
Q +SL P I+ + N+ GHS G+ + S V+A P V +
Sbjct: 332 QPAGSRSLEPSGILLKSGNYSGHS------------DGISSSRSQAVEA-PSVSVNHYSP 378
Query: 68 KGEQFVFEKGEYPRWDSWTSSRR--------TDSLSSLRPIKVDSQEHKIILYENPNFTG 119
Q + K Y + + +RR + L SLR + ++ ++ G
Sbjct: 379 NSHQHIDWK-NYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQVVPNRTTLQG 437
Query: 120 KKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGY 154
++ D VP Q VS R++ + Y
Sbjct: 438 RRRSTSHDRVPQ-SVQIRQRSVSQERLEDSVLMKY 471
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 1 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKE 43
M++ HQ QA QS + + EQ+ GH H G P+ ++
Sbjct: 957 MSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQED 999
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 1 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKE 43
M++ HQ QA QS + + EQ+ GH H G P+ ++
Sbjct: 1511 MSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQED 1553
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 1 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKE 43
M++ HQ QA QS + + EQ+ GH H G P+ ++
Sbjct: 1511 MSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQED 1553
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 27.7 bits (60), Expect = 7.1
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 72 FVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHK 108
+ EK E +W+S + TDS+ +L IK ++E K
Sbjct: 299 YAAEKEERQQWESRERKKITDSIEALAMIKQRAEERK 335
>gi|38570064 hypothetical protein LOC136895 [Homo sapiens]
Length = 590
Score = 27.7 bits (60), Expect = 7.1
Identities = 16/81 (19%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 118 TGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDF 177
+ K+M + D++P+ H Q+ + + Y+ P + L D K
Sbjct: 373 SSKEMVALSDNIPAGVTHKNQDIEEKIIEEQSLLSTYELPSCYPTKDLTSIYDIK----- 427
Query: 178 GAPHPQVQSVRRIRDMQWHQR 198
P P++ ++ D+ W Q+
Sbjct: 428 --PFPKITDTKKTEDLYWRQQ 446
>gi|95147333 phospholipase C, beta 2 [Homo sapiens]
Length = 1185
Score = 27.3 bits (59), Expect = 9.3
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 12 PQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGP-----WVGYEQAN 66
P+ L KI+I ++N + +GP + K+TG E GS A W G E
Sbjct: 451 PEDLRGKILIKNKKN------QFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTE 504
Query: 67 CKGEQFVFEKGE 78
+ E+ E+ E
Sbjct: 505 LEEEEVEEEEEE 516
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 27.3 bits (59), Expect = 9.3
Identities = 21/91 (23%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 121 KMEIIDDDVPSFHAHGYQEKVSSVR----VQSGTWVGY--QYPGYRGLQYLLEKGDYKDS 174
K+ ++ D Q+ SSV V GT +G + + Q + YK++
Sbjct: 6129 KITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEA 6188
Query: 175 SDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN 205
G P P + V+R+++ Q H + N
Sbjct: 6189 IGQGTPIPDLPEVKRVKETQKHISSVMYKEN 6219
>gi|122114658 hypothetical protein LOC23053 [Homo sapiens]
Length = 1842
Score = 27.3 bits (59), Expect = 9.3
Identities = 12/43 (27%), Positives = 21/43 (48%)
Query: 105 QEHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQ 147
+EH + P +ME++ + HAHGY + S + V+
Sbjct: 753 EEHDLFAGLKPLEQESRMEVLFACAEALHAHGYSSEASRLTVE 795
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,728,344
Number of Sequences: 37866
Number of extensions: 392456
Number of successful extensions: 725
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 572
Number of HSP's gapped (non-prelim): 48
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.