Guide to the Human Genome
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Name: CDK8 Sequence: fasta or formatted (464aa) NCBI GI: 4502745
Description:

cyclin-dependent kinase 8

Referenced in:

Cyclins and Related Functions
RNA Polymerase and General Transcription Factors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4         25           2
 C cysteine            1.3          6           1
 D aspartate           7.1         33           2
 E glutamate           5.2         24           3
 F phenylalanine       3.7         17           1
 G glycine             5.8         27           2
 H histidine           4.7         22           2
 I isoleucine          5.0         23           2
 K lysine              8.4         39           2
 L leucine             8.6         40           3
 M methionine          2.8         13           1
 N asparagine          3.4         16           2
 P proline             7.1         33           2
 Q glutamine           5.2         24           5
 R arginine            5.2         24           2
 S serine              6.0         28           2
 T threonine           5.0         23           3
 V valine              4.5         21           3
 W tryptophan          1.3          6           1
 Y tyrosine            4.3         20           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cyclin-dependent kinase 8 
CDC2L6                0.800   cell division cycle 2-like 6 (CDK8-like) 
CDC2L1                0.192   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.192   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.192   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.192   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.192   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.192   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDK3                  0.190   cyclin-dependent kinase 3 
CDC2L2                0.189   cell division cycle 2-like 2 isoform 4 
CDC2L2                0.189   cell division cycle 2-like 2 isoform 1 
CDC2                  0.184   cell division cycle 2 isoform 1 
CDC2                  0.182   cell division cycle 2 isoform 3 
CDK2                  0.181   cyclin-dependent kinase 2 isoform 1 
CDK10                 0.181   cyclin-dependent kinase 10 isoform a 
CDK5                  0.174   cyclin-dependent kinase 5 
CRKRS                 0.168   Cdc2-related kinase, arginine/serine-rich isoform 2...
CRKRS                 0.168   Cdc2-related kinase, arginine/serine-rich isoform 1...
CDK10                 0.165   cyclin-dependent kinase 10 isoform b 
CDC2L5                0.164   cell division cycle 2-like 5 isoform 2 
CDK7                  0.163   cyclin-dependent kinase 7 
CDC2L5                0.162   cell division cycle 2-like 5 isoform 1 
CDK10                 0.161   cyclin-dependent kinase 10 isoform d 
PCTK1                 0.160   PCTAIRE protein kinase 1 isoform 2 
PCTK1                 0.160   PCTAIRE protein kinase 1 isoform 1 
PCTK2                 0.153   PCTAIRE protein kinase 2 
CDK4                  0.152   cyclin-dependent kinase 4 
CDK10                 0.149   cyclin-dependent kinase 10 isoform c 
CDK9                  0.148   cyclin-dependent kinase 9 
CDK6                  0.147   cyclin-dependent kinase 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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