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Search of human proteins with 4502187
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502187 aquaporin 7 [Homo sapiens]
(342 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502187 aquaporin 7 [Homo sapiens] 695 0.0
gi|4826645 aquaporin 3 [Homo sapiens] 275 3e-74
gi|157266307 aquaporin 9 [Homo sapiens] 246 2e-65
gi|22538420 aquaporin 10 [Homo sapiens] 234 1e-61
gi|4502179 aquaporin 2 [Homo sapiens] 96 5e-20
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens] 87 2e-17
gi|4755125 aquaporin 4 isoform b [Homo sapiens] 83 4e-16
gi|4502181 aquaporin 4 isoform a [Homo sapiens] 83 4e-16
gi|86792455 aquaporin 6 [Homo sapiens] 80 2e-15
gi|4502183 aquaporin 5 [Homo sapiens] 79 4e-15
gi|37694062 aquaporin 1 [Homo sapiens] 65 1e-10
gi|45446752 aquaporin 8 [Homo sapiens] 58 1e-08
gi|38327037 hyperpolarization activated cyclic nucleotide-gated ... 32 1.1
gi|148612887 choline transporter-like protein 4 [Homo sapiens] 30 2.4
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ... 30 3.1
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 30 4.1
gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo ... 29 7.0
gi|239755199 PREDICTED: hypothetical protein [Homo sapiens] 28 9.1
gi|16445357 hypothetical protein LOC116843 [Homo sapiens] 28 9.1
>gi|4502187 aquaporin 7 [Homo sapiens]
Length = 342
Score = 695 bits (1793), Expect = 0.0
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVL 60
MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVL
Sbjct: 1 MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVL 60
Query: 61 NKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQF 120
NKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQF
Sbjct: 61 NKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQF 120
Query: 121 LGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTG 180
LGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTG
Sbjct: 121 LGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTG 180
Query: 181 MLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIA 240
MLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIA
Sbjct: 181 MLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIA 240
Query: 241 GWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITV 300
GWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITV
Sbjct: 241 GWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITV 300
Query: 301 LPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF 342
LPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
Sbjct: 301 LPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF 342
>gi|4826645 aquaporin 3 [Homo sapiens]
Length = 292
Score = 275 bits (704), Expect = 3e-74
Identities = 125/262 (47%), Positives = 183/262 (69%), Gaps = 1/262 (0%)
Query: 29 LQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNK-KYGSYLGVNLGFGFGVTMGVHVAGR 87
++ +++R+ LAE + T ++++FG GSVA +VL++ +G +L +NL FGF VT+G+ +AG+
Sbjct: 17 IRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQ 76
Query: 88 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM 147
+SGAH+N AVTFA C L R PW K P+Y L Q LG+FL A ++ L+Y AI HF+ QL
Sbjct: 77 VSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLF 136
Query: 148 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG 207
V+GP TAGIFATY H+ + GF ++ T L +C+ AI D NNP G EA +G
Sbjct: 137 VSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVG 196
Query: 208 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYL 267
++V++IG S+G N+GYA+NP+RD PR+FT +AGWG VF+ G++WWWVP+V+PLLG+
Sbjct: 197 LVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIA 256
Query: 268 GGIIYLVFIGSTIPREPLKLED 289
G +Y + IG + + P E+
Sbjct: 257 GVFVYQLMIGCHLEQPPPSNEE 278
>gi|157266307 aquaporin 9 [Homo sapiens]
Length = 295
Score = 246 bits (628), Expect = 2e-65
Identities = 111/250 (44%), Positives = 174/250 (69%), Gaps = 1/250 (0%)
Query: 28 ILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNK-KYGSYLGVNLGFGFGVTMGVHVAG 86
+L+ + +E L+EF+ T++++V G G VA +L++ ++G + +N+GF V M ++VAG
Sbjct: 17 VLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAG 76
Query: 87 RISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQL 146
+SG H+N AV+ A C GR+ W K P YV QFLG+F+ AAT++ ++Y ++ F+GG+L
Sbjct: 77 GVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKL 136
Query: 147 MVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVI 206
++ G ATA IFATY +++L F ++ T +L + +FAI D N A G E + I
Sbjct: 137 LIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAI 196
Query: 207 GILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAY 266
G+L+++I SLG+N+G A+NP+RDL PR+FT +AGWG +VF G N+WW+PVV PL+GA
Sbjct: 197 GLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAV 256
Query: 267 LGGIIYLVFI 276
+GG+IY++ I
Sbjct: 257 IGGLIYVLVI 266
>gi|22538420 aquaporin 10 [Homo sapiens]
Length = 301
Score = 234 bits (596), Expect = 1e-61
Identities = 112/261 (42%), Positives = 169/261 (64%), Gaps = 1/261 (0%)
Query: 33 MVREFLAEFMSTYVMMVFGLGSVAHMVLN-KKYGSYLGVNLGFGFGVTMGVHVAGRISGA 91
+ R+ LAEF+ +V+M+ G+VA V + + G++ + L VT+ ++V G +SGA
Sbjct: 20 LARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGA 79
Query: 92 HMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGP 151
H+N A + A C +GR+PW K P+Y+L Q L +F A+ Y L++ A+ +++GG L VTGP
Sbjct: 80 HLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGP 139
Query: 152 VATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVV 211
TA IFATY +++L GFL++ TGML + L AI D+ N G E +V+G+L++
Sbjct: 140 KETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLIL 199
Query: 212 IIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGII 271
+G+S+G N G +NP+RDL PR+FT++AGWG +VFS G WWWVPVVAPL+GA +G
Sbjct: 200 ALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGTAT 259
Query: 272 YLVFIGSTIPREPLKLEDSVA 292
Y + + P P +D V+
Sbjct: 260 YQLLVALHHPEGPEPAQDLVS 280
>gi|4502179 aquaporin 2 [Homo sapiens]
Length = 271
Score = 95.9 bits (237), Expect = 5e-20
Identities = 85/240 (35%), Positives = 117/240 (48%), Gaps = 33/240 (13%)
Query: 35 REFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMN 94
R AEF++T + + FGLGS + + S L + + FG G+ V G ISGAH+N
Sbjct: 11 RAVFAEFLATLLFVFFGLGSALNWP--QALPSVLQIAMAFGLGIGTLVQALGHISGAHIN 68
Query: 95 AAVTFANCALG-RVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVA 153
AVT A C +G V + YV Q LG+ AA ++ + I G L V
Sbjct: 69 PAVTVA-CLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADI----RGDLAVNA--- 120
Query: 154 TAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVII 213
L + T + E +LT L LC+FA TD E PGT AL IG V +
Sbjct: 121 --------LSNSTTAGQAVTVELFLTLQLVLCIFASTD-ERRGENPGTPALSIGFSVA-L 170
Query: 214 GVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIY 272
G LG++ TG ++NP+R L P + T GK F + WV + PL+GA LG ++Y
Sbjct: 171 GHLLGIHYTGCSMNPARSLAPAVVT-----GK--FDD----HWVFWIGPLVGAILGSLLY 219
>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
Length = 263
Score = 87.4 bits (215), Expect = 2e-17
Identities = 75/247 (30%), Positives = 107/247 (43%), Gaps = 31/247 (12%)
Query: 27 EILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAG 86
E+ R AEF +T + FGLGS + L V + FG + V G
Sbjct: 3 ELRSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPLH--VLQVAMAFGLALATLVQSVG 60
Query: 87 RISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQL 146
ISGAH+N AVTFA ++ + Y+ Q LG+ AA +YS
Sbjct: 61 HISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYS-------------- 106
Query: 147 MVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVI 206
VT P + L +++ + E +LT LC+FA D+ N L G+ AL +
Sbjct: 107 -VTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQL-GSVALAV 164
Query: 207 GILVVIIGVSLGM-NTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGA 265
G + +G GM TG +NP+R P I T F+N WV V P++G
Sbjct: 165 GFSLA-LGHLFGMYYTGAGMNPARSFAPAILT-------GNFTN----HWVYWVGPIIGG 212
Query: 266 YLGGIIY 272
LG ++Y
Sbjct: 213 GLGSLLY 219
>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
Length = 301
Score = 82.8 bits (203), Expect = 4e-16
Identities = 66/236 (27%), Positives = 104/236 (44%), Gaps = 29/236 (12%)
Query: 39 AEFMSTYVMMVFGLGSVAHMVLNKKY--GSYLGVNLGFGFGVTMGVHVAGRISGAHMNAA 96
AEF++ + ++ LGS + +K + ++L FG + V G ISG H+N A
Sbjct: 18 AEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPA 77
Query: 97 VTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAG 156
VT A ++ K Y+ Q LG+ + A +Y +VT P G
Sbjct: 78 VTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILY---------------LVTPPSVVGG 122
Query: 157 IFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVS 216
+ T + ++T G L E +T L +FA D + + G+ AL IG V I +
Sbjct: 123 LGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD-VTGSIALAIGFSVAIGHLF 181
Query: 217 LGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIY 272
TG ++NP+R P + + N EN W+ V P++GA L G +Y
Sbjct: 182 AINYTGASMNPARSFGPAV----------IMGNWEN-HWIYWVGPIIGAVLAGGLY 226
>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
Length = 323
Score = 82.8 bits (203), Expect = 4e-16
Identities = 66/236 (27%), Positives = 104/236 (44%), Gaps = 29/236 (12%)
Query: 39 AEFMSTYVMMVFGLGSVAHMVLNKKY--GSYLGVNLGFGFGVTMGVHVAGRISGAHMNAA 96
AEF++ + ++ LGS + +K + ++L FG + V G ISG H+N A
Sbjct: 40 AEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPA 99
Query: 97 VTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAG 156
VT A ++ K Y+ Q LG+ + A +Y +VT P G
Sbjct: 100 VTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILY---------------LVTPPSVVGG 144
Query: 157 IFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVS 216
+ T + ++T G L E +T L +FA D + + G+ AL IG V I +
Sbjct: 145 LGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD-VTGSIALAIGFSVAIGHLF 203
Query: 217 LGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIY 272
TG ++NP+R P + + N EN W+ V P++GA L G +Y
Sbjct: 204 AINYTGASMNPARSFGPAV----------IMGNWEN-HWIYWVGPIIGAVLAGGLY 248
>gi|86792455 aquaporin 6 [Homo sapiens]
Length = 282
Score = 80.5 bits (197), Expect = 2e-15
Identities = 77/245 (31%), Positives = 107/245 (43%), Gaps = 33/245 (13%)
Query: 29 LQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRI 88
L + + R AEF++T + + FG+GSV M S L + + F M V V +
Sbjct: 19 LWKAISRALFAEFLATGLYVFFGVGSV--MRWPTALPSVLQIAITFNLVTAMAVQVTWKA 76
Query: 89 SGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMV 148
SGAH N AVT A + + YV Q +G+ + AA +Y + I G +V
Sbjct: 77 SGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGIN-VV 135
Query: 149 TGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGI 208
V+T A E LT L LC+FA TD P T +IGI
Sbjct: 136 RNSVSTGQAVAV--------------ELLLTLQLVLCVFASTDSRQTSGSPAT---MIGI 178
Query: 209 LVVIIGVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYL 267
V +G +G++ TG ++NP+R P I GK WV V PL+GA L
Sbjct: 179 SVA-LGHLIGIHFTGCSMNPARSFGPAIII-----GKFTVH------WVFWVGPLMGALL 226
Query: 268 GGIIY 272
+IY
Sbjct: 227 ASLIY 231
>gi|4502183 aquaporin 5 [Homo sapiens]
Length = 265
Score = 79.3 bits (194), Expect = 4e-15
Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 32/253 (12%)
Query: 26 QEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVA 85
+E+ ++ AEF++T + + FGLGS + + L + L FG +
Sbjct: 3 KEVCSVAFLKAVFAEFLATLIFVFFGLGSA--LKWPSALPTILQIALAFGLAIGTLAQAL 60
Query: 86 GRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQ 145
G +SG H+N A+T A ++ + YV Q +G+ A +Y +
Sbjct: 61 GPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGV------------ 108
Query: 146 LMVTGPVATAGIFA-TYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEAL 204
P+ G A L ++ T + + E LT L LC+FA TD + G+ AL
Sbjct: 109 ----APLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPV-GSPAL 163
Query: 205 VIGILVVIIGVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLL 263
IG L V +G +G+ TG ++NP+R P + V + WV V P++
Sbjct: 164 SIG-LSVTLGHLVGIYFTGCSMNPARSFGPAV----------VMNRFSPAHWVFWVGPIV 212
Query: 264 GAYLGGIIYLVFI 276
GA L I+Y +
Sbjct: 213 GAVLAAILYFYLL 225
>gi|37694062 aquaporin 1 [Homo sapiens]
Length = 269
Score = 64.7 bits (156), Expect = 1e-10
Identities = 70/252 (27%), Positives = 112/252 (44%), Gaps = 34/252 (13%)
Query: 27 EILQRKMVREFLAEFMSTYVMMVFGLGSVA---HMVLNKKYG--SYLGVNLGFGFGVTMG 81
E ++ R +AEF++T + + +GS + V N + + V+L FG +
Sbjct: 4 EFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATL 63
Query: 82 VHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHF 141
G ISGAH+N AVT ++ + +Y++ Q +G+ +A TAIL
Sbjct: 64 AQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVA---------TAIL-- 112
Query: 142 SGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGT 201
SG +T + + L D + +G E T L LC+ A TD+ L G+
Sbjct: 113 SG----ITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRD-LGGS 167
Query: 202 EALVIGILVVIIGVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVA 260
L IG L V +G L ++ TG INP+R +G V ++ + W+ V
Sbjct: 168 APLAIG-LSVALGHLLAIDYTGCGINPAR-----------SFGSAVITHNFSNHWIFWVG 215
Query: 261 PLLGAYLGGIIY 272
P +G L +IY
Sbjct: 216 PFIGGALAVLIY 227
>gi|45446752 aquaporin 8 [Homo sapiens]
Length = 261
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/261 (26%), Positives = 103/261 (39%), Gaps = 40/261 (15%)
Query: 32 KMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGA 91
+ V+ L E + + + + G SV + N L L G + + + G ISG
Sbjct: 33 RFVQPCLVELLGSALFIFIGCLSV---IENGTDTGLLQPALAHGLALGLVIATLGNISGG 89
Query: 92 HMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVT-- 149
H N AV+ A +G + Y + Q LG L AA ++ + G VT
Sbjct: 90 HFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQ 149
Query: 150 --GPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQL--CLFAITDQENNPALPGTEALV 205
G VA A + E LT +L L C+ AI ++ P P
Sbjct: 150 EQGQVAGA----------------LVAEIILTTLLALAVCMGAINEKTKGPLAP----FS 189
Query: 206 IGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGA 265
IG V + ++ G +G +NP+R +G V +N N+ W+ + PLL
Sbjct: 190 IGFAVTVDILAGGPVSGGCMNPAR-----------AFGPAVVANHWNFHWIYWLGPLLAG 238
Query: 266 YLGGIIYLVFIGSTIPREPLK 286
L G++ FIG R LK
Sbjct: 239 LLVGLLIRCFIGDGKTRLILK 259
>gi|38327037 hyperpolarization activated cyclic nucleotide-gated
potassium channel 3 [Homo sapiens]
Length = 774
Score = 31.6 bits (70), Expect = 1.1
Identities = 40/131 (30%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 214 GVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVV-APLLGAYLGGIIY 272
G S G+ + + RD+ + G Q+ +G+ W P+V APL A +
Sbjct: 564 GSSGGIMEQHLVQHDRDMARGVRGRAPSTGAQL--SGKPVLWEPLVHAPLQAA---AVTS 618
Query: 273 LVFIGSTIPREPLKLEDSVAYEDHGITVLPKMG--SHEPTISPLTPVSVSPANRSSVHPA 330
V I T R PL L D T+L + S SPL PV P +S PA
Sbjct: 619 NVAIALTHQRGPLPLSP-----DSPATLLARSAWRSAGSPASPLVPVRAGPWASTSRLPA 673
Query: 331 PP---LHESMA 338
PP LH S++
Sbjct: 674 PPARTLHASLS 684
>gi|148612887 choline transporter-like protein 4 [Homo sapiens]
Length = 710
Score = 30.4 bits (67), Expect = 2.4
Identities = 12/29 (41%), Positives = 19/29 (65%)
Query: 239 IAGWGKQVFSNGENWWWVPVVAPLLGAYL 267
I G GK S N++W+P++ +LGAY+
Sbjct: 622 IPGLGKDFKSPHLNYYWLPIMTSILGAYV 650
>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
sapiens]
Length = 828
Score = 30.0 bits (66), Expect = 3.1
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Query: 307 HEPTISPLTPVSVSPANRSSVHPA--PPLHESM 337
H PT SP S+ P S+HP+ PP H S+
Sbjct: 26 HPPTHSPSIHPSIHPPTHPSIHPSIHPPTHPSI 58
Score = 28.5 bits (62), Expect = 9.1
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Query: 302 PKMGSHEPTISPLTPVSVSPANRSSVHPA--PPLHESM 337
P S P I P S+ P SS+HP+ PP H S+
Sbjct: 75 PTHPSIHPLIHPSIHPSLHPPTHSSIHPSTHPPTHSSI 112
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
[Homo sapiens]
Length = 3969
Score = 29.6 bits (65), Expect = 4.1
Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Query: 289 DSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSS 326
DS A E+ I VLP+ S P + P P+S SP N S+
Sbjct: 489 DSQASEE--IQVLPEERSDTPEVHPPLPISQSPENESN 524
>gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo
sapiens]
Length = 475
Score = 28.9 bits (63), Expect = 7.0
Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 306 SHEPTISPLTPVSVSPANRSSVHPA--PPLHESM 337
S P+I P SV P+N SVHP+ P H S+
Sbjct: 105 STHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSI 138
>gi|239755199 PREDICTED: hypothetical protein [Homo sapiens]
Length = 279
Score = 28.5 bits (62), Expect = 9.1
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 306 SHEPTISPLTPVSVSPANRSSVHPA--PPLHES 336
S P+I P S+ P R S+HP+ PP+H S
Sbjct: 70 SIHPSIHPPVHPSIHPPTRPSIHPSIHPPVHLS 102
>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
Length = 456
Score = 28.5 bits (62), Expect = 9.1
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 18/96 (18%)
Query: 43 STYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANC 102
+T + M+FG ++ ++ + +G+YL V++G F G+ V+G VT
Sbjct: 69 NTIIGMIFGCFALFELLASLVFGNYL-VHIGAKFMFVAGMFVSG---------GVTILFG 118
Query: 103 ALGRVPWRKFPVYVLGQFL------GSFLAAATIYS 132
L RVP PV++ FL SF AA T S
Sbjct: 119 VLDRVP--DGPVFIAMCFLVRVMDAVSFAAAMTASS 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,665,650
Number of Sequences: 37866
Number of extensions: 564336
Number of successful extensions: 1976
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1916
Number of HSP's gapped (non-prelim): 39
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.