BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo sapiens] (191 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo s... 431 e-121 gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo ... 421 e-118 gi|33356558 amelogenin (X chromosome) isoform 2 precursor [Homo ... 382 e-107 gi|4502073 amelogenin, Y-linked precursor [Homo sapiens] 376 e-105 gi|151301053 RNA binding motif protein 33 [Homo sapiens] 79 2e-15 gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 74 6e-14 gi|117938768 GNAS complex locus alex [Homo sapiens] 62 2e-10 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 60 9e-10 gi|50345997 E1A binding protein p300 [Homo sapiens] 60 1e-09 gi|19923345 RNA binding motif protein 12 [Homo sapiens] 59 3e-09 gi|23510462 RNA binding motif protein 12 [Homo sapiens] 59 3e-09 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 59 3e-09 gi|195232763 ADAM metallopeptidase domain 29 preproprotein [Homo... 59 3e-09 gi|195232761 ADAM metallopeptidase domain 29 preproprotein [Homo... 59 3e-09 gi|195232759 ADAM metallopeptidase domain 29 preproprotein [Homo... 59 3e-09 gi|73765552 ADAM metallopeptidase domain 29 preproprotein [Homo ... 59 3e-09 gi|153792074 proline rich 12 [Homo sapiens] 59 3e-09 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 57 7e-09 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 57 7e-09 gi|114431236 zinc finger protein 462 [Homo sapiens] 55 4e-08 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 55 5e-08 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 55 5e-08 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 54 6e-08 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 54 6e-08 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 54 6e-08 gi|146134388 YLP motif containing 1 [Homo sapiens] 54 6e-08 gi|150417989 cyclin K isoform 1 [Homo sapiens] 54 8e-08 gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 53 2e-07 gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 53 2e-07 gi|210032580 SET domain containing 1B [Homo sapiens] 52 2e-07 >gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo sapiens] Length = 191 Score = 431 bits (1108), Expect = e-121 Identities = 191/191 (100%), Positives = 191/191 (100%) Query: 1 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW 60 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW Sbjct: 1 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW 60 Query: 61 LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120 LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP Sbjct: 61 LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120 Query: 121 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP Sbjct: 121 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 Query: 181 STDKTKREEVD 191 STDKTKREEVD Sbjct: 181 STDKTKREEVD 191 >gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo sapiens] Length = 205 Score = 421 bits (1083), Expect = e-118 Identities = 191/205 (93%), Positives = 191/205 (93%), Gaps = 14/205 (6%) Query: 1 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYE--------------VLTPLKWYQSIR 46 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYE VLTPLKWYQSIR Sbjct: 1 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYENSHSQAINVDRTALVLTPLKWYQSIR 60 Query: 47 PPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQ 106 PPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQ Sbjct: 61 PPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQ 120 Query: 107 HSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 166 HSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP Sbjct: 121 HSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 180 Query: 167 LPPMLPDLTLEAWPSTDKTKREEVD 191 LPPMLPDLTLEAWPSTDKTKREEVD Sbjct: 181 LPPMLPDLTLEAWPSTDKTKREEVD 205 >gi|33356558 amelogenin (X chromosome) isoform 2 precursor [Homo sapiens] Length = 175 Score = 382 bits (982), Expect = e-107 Identities = 175/191 (91%), Positives = 175/191 (91%), Gaps = 16/191 (8%) Query: 1 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW 60 MGTWILFACLLGAAFAMP VLTPLKWYQSIRPPYPSYGYEPMGGW Sbjct: 1 MGTWILFACLLGAAFAMP----------------VLTPLKWYQSIRPPYPSYGYEPMGGW 44 Query: 61 LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120 LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP Sbjct: 45 LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 104 Query: 121 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP Sbjct: 105 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 164 Query: 181 STDKTKREEVD 191 STDKTKREEVD Sbjct: 165 STDKTKREEVD 175 >gi|4502073 amelogenin, Y-linked precursor [Homo sapiens] Length = 192 Score = 376 bits (966), Expect = e-105 Identities = 169/192 (88%), Positives = 179/192 (93%), Gaps = 1/192 (0%) Query: 1 MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQS-IRPPYPSYGYEPMGG 59 MGTWILFACL+GAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQS IRPPY SYGYEPMGG Sbjct: 1 MGTWILFACLVGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSMIRPPYSSYGYEPMGG 60 Query: 60 WLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL 119 WLHHQIIPV+SQQHP THTLQ HHHIPVVPAQQP + QQ +MPVPGQ SMTP QHHQPNL Sbjct: 61 WLHHQIIPVVSQQHPLTHTLQSHHHIPVVPAQQPRVRQQALMPVPGQQSMTPTQHHQPNL 120 Query: 120 PPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAW 179 P PAQQP+QPQPVQPQPHQPMQPQPPV PMQPL PQPPLPPMFP++PLPP+LPDL LEAW Sbjct: 121 PLPAQQPFQPQPVQPQPHQPMQPQPPVQPMQPLLPQPPLPPMFPLRPLPPILPDLHLEAW 180 Query: 180 PSTDKTKREEVD 191 P+TDKTK+EEVD Sbjct: 181 PATDKTKQEEVD 192 >gi|151301053 RNA binding motif protein 33 [Homo sapiens] Length = 1170 Score = 79.0 bits (193), Expect = 2e-15 Identities = 57/163 (34%), Positives = 73/163 (44%), Gaps = 28/163 (17%) Query: 20 PPHPGHPGYINFSYEVLT--PLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTH 77 PP P P +N S+ V T PL + Q P P++ + PV ++ P Sbjct: 483 PPPPPPPTLLNSSHPVPTQSPLPFTQ----PGPAFNQQGQQ--------PVFPRERPVRP 530 Query: 78 TLQPHHHIPVVPAQQP--------VIPQQPMMPVPGQHSMTPIQHHQPNLP----PPAQQ 125 LQP + ++ QP + P+QP +P PGQ + H QPNL PP Sbjct: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPT--HTQPNLQGPLHPPLPP 588 Query: 126 PYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168 P+QPQP QPQ P Q QPP P PPQ PP P Q P Sbjct: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPP 631 Score = 52.4 bits (124), Expect = 2e-07 Identities = 40/107 (37%), Positives = 45/107 (42%), Gaps = 13/107 (12%) Query: 66 IPVLSQQHPPTHT---LQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPP 122 +P Q PTHT LQ H P+ P QP PQQP P QH P+ PP Sbjct: 562 LPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQ-PQQPQQ-------QPPPQHQPPHQPPH 613 Query: 123 AQQP-YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168 P +QP P P H P H +PP PPL PM Q P Sbjct: 614 QPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPP-PPLMPMSQPQFRP 659 Score = 50.8 bits (120), Expect = 7e-07 Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 27/95 (28%) Query: 83 HHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP----YQPQPVQP---- 134 H ++P Q PV+PQ P P PPP QQP +QPQP+QP Sbjct: 304 HRPALLPTQPPVVPQAP----------------PPPPPPPQQQPIRSLFQPQPLQPLLPV 347 Query: 135 -QPHQPMQPQPPVHPMQPLPPQPPL--PPMFPMQP 166 PH P PQ P Q P+ + PP+ P QP Sbjct: 348 QHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQP 382 Score = 45.8 bits (107), Expect = 2e-05 Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 25/145 (17%) Query: 43 QSIRPPYPSYGYEPMGGWLHHQII-PVLSQQHPPTHTLQPHHHIP-------VVPAQQPV 94 Q+ PP P +P+ Q + P+L QHP + H+P ++ PV Sbjct: 318 QAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPV 377 Query: 95 IPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQP-----HQPMQPQPPVHPM 149 PQQP ++ H + + P Q P P P QP+P P P+ P H Sbjct: 378 TPQQPK-------NIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTP 430 Query: 150 QPLPPQPPLPPMFPMQ-----PLPP 169 P+P PP P+Q P PP Sbjct: 431 GPVPNSFSQPPRLPLQDQWRAPPPP 455 Score = 40.8 bits (94), Expect = 7e-04 Identities = 25/58 (43%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Query: 112 IQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169 ++ H+P L P Q P PQ P P P Q QP QP P QP LP P P PP Sbjct: 301 MKDHRPALLP-TQPPVVPQAPPPPPPPPQQ-QPIRSLFQPQPLQPLLPVQHPHHPSPP 356 Score = 40.4 bits (93), Expect = 0.001 Identities = 28/104 (26%), Positives = 38/104 (36%), Gaps = 7/104 (6%) Query: 63 HQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPP 122 HQ P QHPP H HHH +P P+MP+ +Q QP Sbjct: 619 HQPPPQHPPQHPPQHQHHHHHH-------HLSVPPPPLMPMSQPQFRPHVQTAQPQASSS 671 Query: 123 AQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 166 Q Q Q ++ + P+ MQP P+ P+ P Sbjct: 672 RMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAP 715 Score = 39.7 bits (91), Expect = 0.002 Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 46/201 (22%) Query: 18 PLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQII---PVLSQQHP 74 P PP P F + L PL Q P P G +++ P ++ Q P Sbjct: 323 PPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQP 382 Query: 75 PTHTLQPHHHIPVV-PAQQPV--IPQQPMMPV-----PG-----QHSMTPIQHH------ 115 + PH VV P Q P+ +P QP V PG QH+ P+ + Sbjct: 383 KNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPR 442 Query: 116 -----QPNLPPPAQ-----------QPYQPQPVQPQPHQPMQPQPP---VHPMQPLPPQP 156 Q PPP Q +P P + + P P PP ++ P+P Q Sbjct: 443 LPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQS 502 Query: 157 PLP-----PMFPMQPLPPMLP 172 PLP P F Q P+ P Sbjct: 503 PLPFTQPGPAFNQQGQQPVFP 523 Score = 38.5 bits (88), Expect = 0.004 Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 15/70 (21%) Query: 116 QPNLPPPAQQPYQPQP--------VQPQPHQPMQP-QPPVHPMQP----LPPQPPLPPMF 162 QP + P A P P P QPQP QP+ P Q P HP P +PPQ P M Sbjct: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRM- 370 Query: 163 PMQPLPPMLP 172 M PP+ P Sbjct: 371 -MMTPPPVTP 379 Score = 36.6 bits (83), Expect = 0.014 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 7/43 (16%) Query: 137 HQP--MQPQPPVHPMQPLPPQPP-----LPPMFPMQPLPPMLP 172 H+P + QPPV P P PP PP + +F QPL P+LP Sbjct: 304 HRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLP 346 Score = 28.5 bits (62), Expect = 3.7 Identities = 29/130 (22%), Positives = 46/130 (35%), Gaps = 25/130 (19%) Query: 64 QIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQ----QPMMPVPGQH------------ 107 +++ L+QQ + P P +Q + P P++P PG Sbjct: 822 ELLERLAQQQQQLYAPPP----PAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVK 877 Query: 108 ----SMTPIQHHQPN-LPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMF 162 S++ +Q N +P A YQ Q ++ H P QPL P+ P Sbjct: 878 NQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPAD 937 Query: 163 PMQPLPPMLP 172 +P P P Sbjct: 938 VEEPAVPQTP 947 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 74.3 bits (181), Expect = 6e-14 Identities = 56/156 (35%), Positives = 67/156 (42%), Gaps = 28/156 (17%) Query: 17 MPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPT 76 +P+PP P P + P+ I P P P ++ PV PP Sbjct: 247 LPVPPMPPRPPMV--------PMPPRPPIAPMPPMAPVPPGS-----RMAPV-----PPG 288 Query: 77 HTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQP 136 + P +P P PV P PM PVP M P+ P PP A+ P P + P Sbjct: 289 PRMAP---VPPWPPMAPVPPWPPMAPVPTGPPMAPV----PPGPPMARVPPGPPMARVPP 341 Query: 137 HQPMQPQPPVHPMQPLPPQP---PLPPMFPMQPLPP 169 PM P PP PM PLPP P PLPP PM PLPP Sbjct: 342 GPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377 Score = 67.8 bits (164), Expect = 5e-12 Identities = 44/115 (38%), Positives = 48/115 (41%), Gaps = 8/115 (6%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133 PP + P I +P PV P M PVP M P+ P P P P P P Sbjct: 256 PPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTG 315 Query: 134 PQ-----PHQPMQPQPPVHPMQPLPPQPP---LPPMFPMQPLPPMLPDLTLEAWP 180 P P PM PP PM +PP PP LPP PM PLPP P L P Sbjct: 316 PPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGP 370 Score = 63.5 bits (153), Expect = 1e-10 Identities = 42/130 (32%), Positives = 51/130 (39%), Gaps = 28/130 (21%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQP------------------MMPVPGQHS 108 P L P P +P +P + P++P P M PVP Sbjct: 231 PALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPR 290 Query: 109 MTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL------PPMF 162 M P+ P P P P P P P PM P PP PM +PP PP+ PPM Sbjct: 291 MAPVPPWPPMAPVPPWPPMAPVPTGP----PMAPVPPGPPMARVPPGPPMARVPPGPPMA 346 Query: 163 PMQPLPPMLP 172 P+ P PPM P Sbjct: 347 PLPPGPPMAP 356 Score = 53.5 bits (127), Expect = 1e-07 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 25/91 (27%) Query: 93 PVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQP- 151 P +P+ P++PVP P P + P P P +P P+ P PP+ P+ P Sbjct: 239 PQLPRPPVLPVP---------------PMPPRPPMVPMPPRP----PIAPMPPMAPVPPG 279 Query: 152 --LPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 + P PP P M P+ P PPM P + WP Sbjct: 280 SRMAPVPPGPRMAPVPPWPPMAP---VPPWP 307 Score = 51.2 bits (121), Expect = 5e-07 Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 117 PNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169 P L P PQ +P P P+ P PP PM P+PP+PP+ PM PM P+PP Sbjct: 227 PALDPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPP 278 Score = 28.1 bits (61), Expect = 4.8 Identities = 17/52 (32%), Positives = 22/52 (42%), Gaps = 7/52 (13%) Query: 113 QHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLP-------PQPP 157 Q +P L P QQ +P ++ + Q PQ V QP PQPP Sbjct: 85 QQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPP 136 >gi|117938768 GNAS complex locus alex [Homo sapiens] Length = 626 Score = 62.4 bits (150), Expect = 2e-10 Identities = 52/151 (34%), Positives = 69/151 (45%), Gaps = 36/151 (23%) Query: 40 KWYQSIRP----PYPSYGYEPMGGWLHHQIIPVLSQQHP-PTHTLQPHHHIPVVPAQQPV 94 +W + + P YP G +P+ P Q+ P P LQP QP+ Sbjct: 298 RWKEPLMPRREEKYPLRGTDPLP--------PGQPQRIPLPGQPLQP----------QPI 339 Query: 95 I-PQQPM-MPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL 152 + P QP +P PGQH H +P P Q P PQP+ P P +P+ PQP P +PL Sbjct: 340 LTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQ-PLPPQPI-PTPGRPLTPQPIPTPGRPL 397 Query: 153 PPQP------PL---PPMFPMQPLPPMLPDL 174 PQP PL PP+ ++P PM P L Sbjct: 398 TPQPIQMPGRPLRLPPPLRLLRPGQPMSPQL 428 Score = 55.5 bits (132), Expect = 3e-08 Identities = 37/101 (36%), Positives = 45/101 (44%), Gaps = 11/101 (10%) Query: 85 IPVVPAQQPVIPQQPMMP----VPGQHSMTPIQ-HHQPNLPPPAQQPYQPQPVQPQPHQP 139 +P Q+ +P QP+ P PGQ P HQP L P QP P P QP Sbjct: 319 LPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPI------PTPGQP 372 Query: 140 MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 + PQP P +PL PQP P P+ P P +P L P Sbjct: 373 LPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPP 413 Score = 53.1 bits (126), Expect = 1e-07 Identities = 46/121 (38%), Positives = 55/121 (45%), Gaps = 23/121 (19%) Query: 64 QIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQ---PMMPVPGQHSMTPIQHHQPNLP 120 Q IP Q P L P H P+ QP+ PQ P P+ Q TP +P P Sbjct: 346 QKIPTPGQHQP---ILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTP---GRPLTP 399 Query: 121 PPAQQPYQPQPVQP-----QPHQPMQPQPPVHPMQPLP-PQPPLPPMFP------MQPLP 168 P Q P +P + P +P QPM PQ + Q LP PQP LPP P +QPLP Sbjct: 400 QPIQMPGRPLRLPPPLRLLRPGQPMSPQ--LRQTQGLPLPQPLLPPGQPKSAGRPLQPLP 457 Query: 169 P 169 P Sbjct: 458 P 458 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 60.5 bits (145), Expect = 9e-10 Identities = 46/127 (36%), Positives = 55/127 (43%), Gaps = 18/127 (14%) Query: 66 IPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHH---------- 115 IP+L+ P L H + +P Q PV P P + P HH Sbjct: 884 IPLLAVAPPGVAALSIHSAVAQLPGQ-PVYPAA--FPQMAPTDVPPSPHHTVQNMRATPP 940 Query: 116 QPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLP--PMFPMQPLPPMLPD 173 QP LPP P PQPV P P + PQP + P PPQP LP PM P QP+ P P Sbjct: 941 QPALPPQPTLP--PQPVLP-PQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPA 997 Query: 174 LTLEAWP 180 L + P Sbjct: 998 LPVRPEP 1004 Score = 59.3 bits (142), Expect = 2e-09 Identities = 46/123 (37%), Positives = 55/123 (44%), Gaps = 20/123 (16%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQ-PV 132 PP TL P PV+P Q P +P QP++P P+ QP LPP P QP PV Sbjct: 945 PPQPTLPPQ---PVLPPQ-PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPV 1000 Query: 133 QP---QPHQPMQPQPPVHP------MQPLP------PQPPLPPMFPMQPLPPMLPDLTLE 177 +P QPH P Q P P P P Q P P+ P L P LP++ L Sbjct: 1001 RPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLP 1060 Query: 178 AWP 180 A P Sbjct: 1061 AAP 1063 Score = 58.9 bits (141), Expect = 3e-09 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 12/101 (11%) Query: 75 PTHTLQPHHHIPVVPA--QQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPV 132 P HT+Q P PA QP +P QP++P Q ++ P QP LPP +P PQPV Sbjct: 928 PHHTVQNMRATPPQPALPPQPTLPPQPVLPP--QPTLPP----QPVLPPQPTRP--PQPV 979 Query: 133 QPQPHQPMQPQPPVHPMQPLPPQP-PLPPMFPMQPLPPMLP 172 P P + PQP + P LP +P PL P P Q P P Sbjct: 980 LP-PQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019 Score = 58.5 bits (140), Expect = 3e-09 Identities = 44/115 (38%), Positives = 55/115 (47%), Gaps = 22/115 (19%) Query: 71 QQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQ--QPYQ 128 QQ PP P +P V A QPV+P QP+ P H P L P +Q P Q Sbjct: 729 QQPPPLAQPTP---LPQVLAPQPVVPLQPVPP-----------HLPPYLAPASQVGAPAQ 774 Query: 129 PQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPM---QPLPPMLPDLTLEAWP 180 +P+Q P P+QP V P +PP P +PP+ P+ LPP LPDL P Sbjct: 775 LKPLQ-MPQAPLQPLAQVPPQ--MPPIPVVPPITPLAGIDGLPPALPDLPTATVP 826 Score = 54.3 bits (129), Expect = 6e-08 Identities = 34/89 (38%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Query: 91 QQPVI-PQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPM 149 QQP P P+ VP +Q H P+ P + P P P P P P QP PP Sbjct: 673 QQPTAAPGLPVGSVPAPACPPSLQQHFPD-PAMSFAPVLPPPSTPMPTGPGQPAPPGQQP 731 Query: 150 QPLPPQPPLP------PMFPMQPLPPMLP 172 PL PLP P+ P+QP+PP LP Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760 Score = 46.6 bits (109), Expect = 1e-05 Identities = 52/174 (29%), Positives = 65/174 (37%), Gaps = 23/174 (13%) Query: 11 LGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLS 70 L A P+PP P Y FS V+ P S+ P P P L Q + + Sbjct: 820 LPTATVPPVPP----PQY--FSPAVILP-----SLAAPLP-----PASPALPLQAVKL-- 861 Query: 71 QQHPPTHTLQPHHH--IPVVPAQQPVIPQQPM-MPVPGQHSMTPIQHHQPNLPPPAQQPY 127 HPP L +P PA P++ P + HS QP P Q Sbjct: 862 -PHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ-M 919 Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181 P V P PH +Q P LPPQP LPP + P P + P L P+ Sbjct: 920 APTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973 Score = 37.0 bits (84), Expect = 0.010 Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 20/106 (18%) Query: 69 LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPY- 127 L+ + + L H P+ Q V+ P P P S + LPPPA +P Sbjct: 1426 LTSELETSQPLAETHEAPLA-VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484 Query: 128 ---QPQPV--QPQPHQP-----------MQPQPPVHPMQPLPPQPP 157 PQP QP P P P PP+ P +PPQPP Sbjct: 1485 HSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGP--TVPPQPP 1528 Score = 31.6 bits (70), Expect = 0.43 Identities = 25/81 (30%), Positives = 28/81 (34%) Query: 89 PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP 148 PAQ P PV Q + + QP P P P P Q P P + Sbjct: 647 PAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSF 706 Query: 149 MQPLPPQPPLPPMFPMQPLPP 169 LPP P P QP PP Sbjct: 707 APVLPPPSTPMPTGPGQPAPP 727 Score = 30.8 bits (68), Expect = 0.74 Identities = 16/55 (29%), Positives = 24/55 (43%) Query: 100 MMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPP 154 + P Q +P + P +P Q Y Q QP P +P +P+ H + P P Sbjct: 550 LQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLP 604 Score = 29.6 bits (65), Expect = 1.7 Identities = 24/90 (26%), Positives = 32/90 (35%), Gaps = 2/90 (2%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133 PP L P ++PA ++PQ P S+ + L PPA P P Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGI 1104 Query: 134 PQPHQPMQPQPPVHPMQPLPPQPPLPPMFP 163 P + Q V P+Q PP P Sbjct: 1105 ASPCPTV--QLTVEPVQEEQASQDKPPGLP 1132 Score = 27.3 bits (59), Expect = 8.2 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 32/119 (26%) Query: 86 PVVPAQQPV--IPQQPMMP----VPGQHSMTPIQHHQPNLP-----------PPAQQPYQ 128 P+ P+ PV +PQ P +P S T Q P P P A+ Sbjct: 1383 PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEA 1442 Query: 129 PQPVQPQPH--QPMQPQPPVH-------PMQPLPPQPPLPPMFPMQPLP------PMLP 172 P VQP P P P P +PLPP P P P P P+LP Sbjct: 1443 PLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP 1501 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 59.7 bits (143), Expect = 1e-09 Identities = 48/138 (34%), Positives = 57/138 (41%), Gaps = 19/138 (13%) Query: 67 PVLSQQHP---PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPA 123 P L Q P P+ T PHH P + AQQP P PVP +M P Q PPP Sbjct: 825 PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPA-PVPTPPAMPPGPQSQALHPPPR 883 Query: 124 QQPYQPQ---PVQPQPHQPMQPQPPVHPMQPLPPQ-------PPLPPMFPMQPLPPM-LP 172 Q P P P Q QP P P QP Q P P+ P QP P+ P Sbjct: 884 QTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQP 943 Query: 173 DLTLEAW----PSTDKTK 186 +++E PST T+ Sbjct: 944 AVSIEGQVSNPPSTSSTE 961 Score = 52.8 bits (125), Expect = 2e-07 Identities = 49/146 (33%), Positives = 61/146 (41%), Gaps = 17/146 (11%) Query: 47 PPYPSYGYEPMG-GWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPG 105 P PS G P+ + PV S PP + H H P +P QP + Q PVP Sbjct: 781 PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPG-SQGSHIHCPQLP--QPALHQNSPSPVP- 836 Query: 106 QHSMTPIQHHQPNLPPPAQQPYQ--PQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFP 163 S TP HH P Q P P PV P P P P + P P Q P PP Sbjct: 837 --SRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMP--PGPQSQALHPPPRQTPTPPTTQ 892 Query: 164 M-QPLPPMLPDLTLEAWPSTDKTKRE 188 + Q + P LP A PS D+ +++ Sbjct: 893 LPQQVQPSLP-----AAPSADQPQQQ 913 Score = 38.9 bits (89), Expect = 0.003 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 20/99 (20%) Query: 84 HIPVVPA--QQPVIPQQ----------PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQP 131 +IP+ P+ Q PV Q P+MP Q S H P LP PA P P Sbjct: 779 NIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI----HCPQLPQPALHQNSPSP 834 Query: 132 VQPQPHQPMQPQPPVHPMQP----LPPQPPLPPMFPMQP 166 V + P P + QP +P P PP P P Sbjct: 835 VPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGP 873 Score = 38.5 bits (88), Expect = 0.004 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 8/92 (8%) Query: 94 VIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP----PVH-- 147 V+ QQ +P P + T QP P Q QPQP P P P+ PV Sbjct: 1840 VVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899 Query: 148 --PMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177 Q PP PP P+ PP ++ ++ Sbjct: 1900 KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ 1931 Score = 37.4 bits (85), Expect = 0.008 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 9/85 (10%) Query: 79 LQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQH------HQPNLPPPAQQPY-QPQP 131 LQ PV P P+ PQQ M+P Q Q +Q P P P Q QP Sbjct: 2265 LQQQMGSPVQP--NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQP 2322 Query: 132 VQPQPHQPMQPQPPVHPMQPLPPQP 156 P MQPQP H + P P Sbjct: 2323 PHSSPSPRMQPQPSPHHVSPQTSSP 2347 Score = 32.0 bits (71), Expect = 0.33 Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 11/149 (7%) Query: 43 QSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV----IPQQ 98 Q + P P+ P G P + Q PT ++P A PV Q Sbjct: 1845 QGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ 1904 Query: 99 PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQP------HQPMQPQ-PPVHPMQP 151 P P Q + P+ P A Q + Q Q +P+Q Q PP+ PM P Sbjct: 1905 VTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAP 1964 Query: 152 LPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 + PP P L P + ++ P Sbjct: 1965 MGMNPPPMTRGPSGHLEPGMGPTGMQQQP 1993 Score = 32.0 bits (71), Expect = 0.33 Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 12/113 (10%) Query: 71 QQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMT-------PIQHHQPNLPPPA 123 Q PPT +P P + Q Q M PIQH P + P A Sbjct: 1904 QVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMA 1963 Query: 124 QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPP--QPPLPPMFPMQ---PLPPML 171 P P+ P ++P MQ PP Q LP +Q P P M+ Sbjct: 1964 PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMM 2016 Score = 27.7 bits (60), Expect = 6.3 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 125 QPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPML 171 Q YQ + +Q Q P+QP P+ P Q + P P Q +P L Sbjct: 2258 QAYQQRLLQQQMGSPVQPN-PMSPQQHMLPNQAQSPHLQGQQIPNSL 2303 Score = 27.3 bits (59), Expect = 8.2 Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 11/77 (14%) Query: 80 QPHHHIPVVPAQQPVIPQQPMMP-VPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQ 138 QP P +P QP + Q P MP G HS +Q+ P + Q+ P Q QP Q Sbjct: 2098 QPIPGQPGMPQGQPGL-QPPTMPGQQGVHSNPAMQNMNP-MQAGVQRAGLP---QQQPQQ 2152 Query: 139 PMQPQPPVHPMQPLPPQ 155 +QP PM + PQ Sbjct: 2153 QLQP-----PMGGMSPQ 2164 >gi|19923345 RNA binding motif protein 12 [Homo sapiens] Length = 932 Score = 58.9 bits (141), Expect = 3e-09 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 12/90 (13%) Query: 85 IPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP 144 +P + +P P+ P+P S+ P+ P++PP P P P P P+ P P Sbjct: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPM----PSIPPIPVPP--PVPTLP----PVPPVP 224 Query: 145 PVHPMQPLPPQPPLPPMFPMQPL--PPMLP 172 P+ P+ +PP PLPPM M PL PP+ P Sbjct: 225 PIPPVPSVPPMTPLPPMSGMPPLNPPPVAP 254 Score = 43.1 bits (100), Expect = 1e-04 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 8/94 (8%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133 PP ++ P P VP PV P P+ PVP MTP+ P P P PV Sbjct: 200 PPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP------PMSGMPPLNPPPVA 253 Query: 134 PQPHQPMQPQPPVHPMQPLPPQ--PPLPPMFPMQ 165 P P P++ L P PL P+ P+Q Sbjct: 254 PLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQ 287 Score = 37.4 bits (85), Expect = 0.008 Identities = 18/56 (32%), Positives = 27/56 (48%) Query: 126 PYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181 P P+ P P+ P P + + P+P PP+P P+ LPP+ P + PS Sbjct: 176 PSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPS 231 >gi|23510462 RNA binding motif protein 12 [Homo sapiens] Length = 932 Score = 58.9 bits (141), Expect = 3e-09 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 12/90 (13%) Query: 85 IPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP 144 +P + +P P+ P+P S+ P+ P++PP P P P P P+ P P Sbjct: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPM----PSIPPIPVPP--PVPTLP----PVPPVP 224 Query: 145 PVHPMQPLPPQPPLPPMFPMQPL--PPMLP 172 P+ P+ +PP PLPPM M PL PP+ P Sbjct: 225 PIPPVPSVPPMTPLPPMSGMPPLNPPPVAP 254 Score = 43.1 bits (100), Expect = 1e-04 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 8/94 (8%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133 PP ++ P P VP PV P P+ PVP MTP+ P P P PV Sbjct: 200 PPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP------PMSGMPPLNPPPVA 253 Query: 134 PQPHQPMQPQPPVHPMQPLPPQ--PPLPPMFPMQ 165 P P P++ L P PL P+ P+Q Sbjct: 254 PLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQ 287 Score = 37.4 bits (85), Expect = 0.008 Identities = 18/56 (32%), Positives = 27/56 (48%) Query: 126 PYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181 P P+ P P+ P P + + P+P PP+P P+ LPP+ P + PS Sbjct: 176 PSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPS 231 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 58.9 bits (141), Expect = 3e-09 Identities = 55/159 (34%), Positives = 62/159 (38%), Gaps = 25/159 (15%) Query: 22 HPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQP 81 HP PG + V P + PP P G P +H P HPP + P Sbjct: 316 HPPAPGVHPPTSGVHPPAP---GVHPPAP--GVHPPAPGVH----PPAPGVHPPAPGVHP 366 Query: 82 ------HHHIPVV-PAQQPVIPQQPMM--PVPGQHSMTPIQHHQPNLPPPAQQPYQPQPV 132 H P V PA V PQ P + P PG H P H Q PP P P V Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQ----PPGVHPSAP-GV 421 Query: 133 QPQPHQPMQPQPPVHPMQPLPP--QPPLPPMFPMQPLPP 169 PQP P VHP P+PP +PPLP P PP Sbjct: 422 HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPP 460 Score = 53.1 bits (126), Expect = 1e-07 Identities = 57/172 (33%), Positives = 64/172 (37%), Gaps = 31/172 (18%) Query: 19 LPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHT 78 LPP P P E L P PP P G P G Q+ P HPP Sbjct: 241 LPPRPPLP-------ESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPV 293 Query: 79 LQP-----HHHIP-VVPAQQPVIPQQPMM---------PVPGQHSMTPIQH-HQPNLPPP 122 + P H P V P V P P + P PG H P H P + PP Sbjct: 294 VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPP 353 Query: 123 AQQPYQPQP-VQPQPHQPMQPQPP-VHPMQP-LPPQ-----PPLPPMFPMQP 166 A + P P V P P + PQ P VHP P + PQ PP P M P P Sbjct: 354 APGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAP 405 Score = 53.1 bits (126), Expect = 1e-07 Identities = 47/145 (32%), Positives = 53/145 (36%), Gaps = 25/145 (17%) Query: 45 IRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPT---HTLQPHHHIPVVPAQQPVIPQQPMM 101 + PP P G P +H P S HPP H P H P P P Sbjct: 308 VHPPAP--GVHPPAPGVH----PPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPA 361 Query: 102 P-------------VPGQHSMTPIQHHQ-PNLPPPAQQPYQPQP-VQPQPHQPMQPQPPV 146 P PG H P H Q P + PPA + P V PQP P V Sbjct: 362 PGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGV 421 Query: 147 HPMQPLPPQPPLPPMFPMQPLPPML 171 HP QP P P + P P+PPML Sbjct: 422 HP-QPPGVHPSNPGVHPPTPMPPML 445 Score = 44.3 bits (103), Expect = 6e-05 Identities = 43/137 (31%), Positives = 50/137 (36%), Gaps = 19/137 (13%) Query: 22 HPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQP 81 HP PG + V P + PP PS G P +H P + Q P H P Sbjct: 344 HPPAPGVHPPAPGVHPPAP---GVHPP-PSAGVHPQAPGVH-PAAPAVHPQAPGVHPPAP 398 Query: 82 HHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPM- 140 H Q P + QP PG H P H Q PP P P P P PM Sbjct: 399 GMH-----PQAPGVHPQP----PGVHPSAPGVHPQ----PPGVHPSNPGVHPPTPMPPML 445 Query: 141 QPQPPVHPMQPLPPQPP 157 +P P +PP PP Sbjct: 446 RPPLPSEGPGNIPPPPP 462 Score = 42.0 bits (97), Expect = 3e-04 Identities = 38/107 (35%), Positives = 43/107 (40%), Gaps = 11/107 (10%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P L PP L P P P P+ P P P P S P P LPPPA Sbjct: 235 PPLMNGLPPRPPL-PESLPPPPPGGLPLPPMPPTGPAP---SGPP---GPPQLPPPAPGV 287 Query: 127 YQPQPVQPQPHQPMQPQPP-VHPMQP--LPPQPPL-PPMFPMQPLPP 169 + P PV P + P P VHP P PP P + PP + P P Sbjct: 288 HPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAP 334 Score = 37.7 bits (86), Expect = 0.006 Identities = 22/58 (37%), Positives = 26/58 (44%), Gaps = 2/58 (3%) Query: 117 PNLPPPAQQPYQP--QPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172 P PP ++P P + P+P P PP PLPP PP P P PP LP Sbjct: 224 PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLP 281 Score = 35.8 bits (81), Expect = 0.023 Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 93 PVIPQQPMMPVPGQHSMTPIQHHQPNLPP-PAQQPYQPQPVQPQPHQPMQPQPPVHPMQP 151 P P P P + P+ + P PP P P P P P PM P P P Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLP--PPPPGGLPLPPMPPTGPAPSGPP 275 Query: 152 LPPQ--PPLPPMFPMQPL--PP 169 PPQ PP P + P P+ PP Sbjct: 276 GPPQLPPPAPGVHPPAPVVHPP 297 Score = 35.0 bits (79), Expect = 0.039 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 16/88 (18%) Query: 86 PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP 145 P +PA P + + P + G P+ +LPPP P P+ P PP Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLPPRPPLPE---SLPPP-----------PPGGLPLPPMPP 266 Query: 146 VHPMQPLPPQPP-LPPMFP-MQPLPPML 171 P PP PP LPP P + P P++ Sbjct: 267 TGPAPSGPPGPPQLPPPAPGVHPPAPVV 294 Score = 33.9 bits (76), Expect = 0.088 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 10/57 (17%) Query: 124 QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFP--------MQPLPPMLP 172 ++P P + P +P PP+ M LPP+PPLP P + P+PP P Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPL--MNGLPPRPPLPESLPPPPPGGLPLPPMPPTGP 269 >gi|195232763 ADAM metallopeptidase domain 29 preproprotein [Homo sapiens] Length = 820 Score = 58.5 bits (140), Expect = 3e-09 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P+ QQ T + + I P + P Q +MP Q +TP Q H +P +Q P Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172 P QP+ P Q QPPV P Q P P PP+ P Q P ++P Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810 Score = 46.2 bits (108), Expect = 2e-05 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%) Query: 70 SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126 SQ PP Q H + +Q PV P Q +MP Q + P Q H P L P QP Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P Q QP + P Q PP P Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819 >gi|195232761 ADAM metallopeptidase domain 29 preproprotein [Homo sapiens] Length = 820 Score = 58.5 bits (140), Expect = 3e-09 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P+ QQ T + + I P + P Q +MP Q +TP Q H +P +Q P Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172 P QP+ P Q QPPV P Q P P PP+ P Q P ++P Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810 Score = 46.2 bits (108), Expect = 2e-05 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%) Query: 70 SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126 SQ PP Q H + +Q PV P Q +MP Q + P Q H P L P QP Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P Q QP + P Q PP P Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819 >gi|195232759 ADAM metallopeptidase domain 29 preproprotein [Homo sapiens] Length = 820 Score = 58.5 bits (140), Expect = 3e-09 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P+ QQ T + + I P + P Q +MP Q +TP Q H +P +Q P Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172 P QP+ P Q QPPV P Q P P PP+ P Q P ++P Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810 Score = 46.2 bits (108), Expect = 2e-05 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%) Query: 70 SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126 SQ PP Q H + +Q PV P Q +MP Q + P Q H P L P QP Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P Q QP + P Q PP P Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819 >gi|73765552 ADAM metallopeptidase domain 29 preproprotein [Homo sapiens] Length = 820 Score = 58.5 bits (140), Expect = 3e-09 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P+ QQ T + + I P + P Q +MP Q +TP Q H +P +Q P Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172 P QP+ P Q QPPV P Q P P PP+ P Q P ++P Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810 Score = 46.2 bits (108), Expect = 2e-05 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%) Query: 70 SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126 SQ PP Q H + +Q PV P Q +MP Q + P Q H P L P QP Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P Q QP + P Q PP P Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 58.5 bits (140), Expect = 3e-09 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 14/104 (13%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P+L ++ PPT P P QP P P P P S P+ P+ PPP P Sbjct: 1451 PLLEEKPPPTP--------PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLP 1502 Query: 127 YQPQPVQPQPHQPMQP------QPPVHPMQPLPPQPPLPPMFPM 164 P P P P P P PP P P P P LP P+ Sbjct: 1503 PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546 Score = 51.2 bits (121), Expect = 5e-07 Identities = 36/98 (36%), Positives = 43/98 (43%), Gaps = 18/98 (18%) Query: 86 PVVPAQQPVIPQQPMMP-VPGQHSM-TP----IQHHQPNLPPPAQQPYQPQPVQPQPHQP 139 P+ PA +P P +P +P +S TP ++ P PPPA P P P P QP Sbjct: 1423 PLAPAA--AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQP 1480 Query: 140 MQPQPPV--------HPMQPLPPQPPLPPMFPMQPLPP 169 P PP P PLPP P PP P P PP Sbjct: 1481 ALPSPPPLVAPTPSSPPPPPLPPPP--PPAMPSPPPPP 1516 Score = 49.3 bits (116), Expect = 2e-06 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 19/98 (19%) Query: 91 QQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQP---VQPQPHQPMQP--QPP 145 + P++ ++P P P QP PPP QP P P V P P P P PP Sbjct: 1449 EPPLLEEKP----PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504 Query: 146 VHPMQPLPPQPP--------LPPMFPMQPLP--PMLPD 173 P P PP PP PP P P P P LPD Sbjct: 1505 PPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPD 1542 Score = 38.9 bits (89), Expect = 0.003 Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 29/125 (23%) Query: 74 PPT-HTLQPHHHIPVVPAQQP----VIPQQPMMPVP----------------GQHSMTPI 112 PPT + QP H ++ A P V+P P +P G H + P Sbjct: 768 PPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPA 827 Query: 113 QHH-QPNLPPPAQQPYQPQPVQPQPH------QPMQPQPPVHPMQPLPPQPPLPPMF-PM 164 P PPP P P P+Q + H +P P P + P + L P + + + Sbjct: 828 TRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGAL 887 Query: 165 QPLPP 169 +PLPP Sbjct: 888 EPLPP 892 Score = 33.1 bits (74), Expect = 0.15 Identities = 24/75 (32%), Positives = 26/75 (34%), Gaps = 1/75 (1%) Query: 86 PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP 145 P PA P P P G TP PN PP +P+ P Q PP Sbjct: 982 PGPPAYDPYGPYCPGR-ASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040 Query: 146 VHPMQPLPPQPPLPP 160 P P PP P P Sbjct: 1041 PPPPPPPPPAPASEP 1055 Score = 32.7 bits (73), Expect = 0.20 Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 14/91 (15%) Query: 95 IPQQPMMPVPGQHSMTPIQHHQ------PNLP---PPAQQPYQPQPVQPQPH-QPMQPQP 144 + + P P P S P H P+LP PP P + P P + Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKV 819 Query: 145 PVHPMQPLP----PQPPLPPMFPMQPLPPML 171 VH ++P PQPP PP P P+P L Sbjct: 820 GVHLLEPATRDGAPQPPPPPPPPPPPMPLQL 850 Score = 30.0 bits (66), Expect = 1.3 Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 14/82 (17%) Query: 69 LSQQHPP-----THTLQPHHHIPVVPAQQPVIPQQ-PMMPVPGQHSMTPIQHHQPNLPPP 122 LS Q PP L PH + + P+Q P +P + G + P L P Sbjct: 168 LSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP-----AGLGPA 222 Query: 123 AQQPYQPQPVQPQP---HQPMQ 141 PY+P P P P H P Q Sbjct: 223 QTPPYRPGPPDPPPPPRHLPTQ 244 Score = 29.3 bits (64), Expect = 2.2 Identities = 13/31 (41%), Positives = 15/31 (48%) Query: 136 PHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 166 P P + PP P + L PQPP P P P Sbjct: 1306 PLSPPKSVPPSVPARGLQPQPPATPAVPHPP 1336 Score = 29.3 bits (64), Expect = 2.2 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 5/61 (8%) Query: 102 PVPGQHS---MTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL 158 PVP + S P+ + PPP P+P P+ + +PP + P+PP Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPE--KTTSEKPPEQTPETAMPEPPA 1728 Query: 159 P 159 P Sbjct: 1729 P 1729 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 57.4 bits (137), Expect = 7e-09 Identities = 43/124 (34%), Positives = 51/124 (41%), Gaps = 22/124 (17%) Query: 39 LKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQ 98 L+ Q ++PP P ++P + Q P L P H P+ Q + QQ Sbjct: 932 LQQLQKVQPPTP--------------LLPSVKVQSQPPPPLPPPPH----PSVQQQLQQQ 973 Query: 99 PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP---MQPLPPQ 155 P P P Q P Q HQP P QP Q QP P QPP HP QP PPQ Sbjct: 974 PPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP-HPPPGQQPPPPQ 1032 Query: 156 PPLP 159 P P Sbjct: 1033 PAKP 1036 Score = 55.1 bits (131), Expect = 4e-08 Identities = 43/157 (27%), Positives = 64/157 (40%), Gaps = 31/157 (19%) Query: 45 IRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVP 104 + P P ++P+G H P+L H P L PH P + P + Q ++ P Sbjct: 808 LEPQLPGSVFDPIG----HFTQPIL---HLPQPELPPHLPQPPEHSTPPHLNQHAVVSPP 860 Query: 105 GQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL--PPQ------- 155 H+ P QP+ P P+P +P P Q P+ P P+ PPQ Sbjct: 861 ALHNALP---QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917 Query: 156 PPLPPMFPM------------QPLPPMLPDLTLEAWP 180 PP PP+ M QP P+LP + +++ P Sbjct: 918 PPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP 954 Score = 55.1 bits (131), Expect = 4e-08 Identities = 54/177 (30%), Positives = 63/177 (35%), Gaps = 45/177 (25%) Query: 16 AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPP 75 A LPP P P ++ + TPL P P P +L + PP Sbjct: 877 AAALPPKPARPPAVSPAL-TQTPLL-------PQPPMAQPPQ---------VLLEDEEPP 919 Query: 76 THTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPA---------QQP 126 L + Q V P P++P S P P LPPP QQP Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP-----PPLPPPPHPSVQQQLQQQP 974 Query: 127 YQPQPVQPQPHQPMQPQPPVHPM------------QPLPPQPPLPPMFP--MQPLPP 169 P P QPQP Q QPP P+ QP PPQ PP P QP PP Sbjct: 975 PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031 Score = 53.1 bits (126), Expect = 1e-07 Identities = 34/103 (33%), Positives = 38/103 (36%), Gaps = 21/103 (20%) Query: 73 HPPTHTLQPHHHIPVVPAQQPV-IPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQP 131 HP + HHH Q P +PQQP PPP QQP P P Sbjct: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQP--------------------PPPPQQPPPPPP 769 Query: 132 VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDL 174 Q Q P P PP P Q P PP F +P + P L Sbjct: 770 PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812 Score = 49.3 bits (116), Expect = 2e-06 Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 10/159 (6%) Query: 17 MPLPPHPGHPGYINFSYEVLTPLKWYQSI--RPPYPSYGYE--PMGGWLHHQIIPVLSQQ 72 +P PP P ++N + V++P + ++ +P PS P + P L+Q Sbjct: 839 LPQPPEHSTPPHLN-QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQT 897 Query: 73 HPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPN---LPPPAQQPYQP 129 P P P V + P P+ + Q + +Q QP LP Q P Sbjct: 898 --PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP 955 Query: 130 QPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168 P+ P PH +Q Q P P PPQP PP QP P Sbjct: 956 PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP 994 Score = 43.9 bits (102), Expect = 8e-05 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 20/104 (19%) Query: 96 PQQPMMPVPGQHSMTP-IQHHQPNLPPPAQQPYQPQPVQPQ-----------PHQPMQPQ 143 P +P Q S P Q QPN PP P+ V P P QP+Q Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250 Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPSTDKTKR 187 PPV P QP PP P P P+Q PP+ + A P KTK+ Sbjct: 251 PPV-PPQPQPPPAPAPQ--PVQSHPPI-----IAATPQPVKTKK 286 Score = 43.5 bits (101), Expect = 1e-04 Identities = 60/231 (25%), Positives = 78/231 (33%), Gaps = 64/231 (27%) Query: 18 PLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTH 77 PLPP P HP + P Q PP + P L QQ PP Sbjct: 957 PLPPPP-HPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQ 1015 Query: 78 TLQPHHHIPVVPAQQPVIPQ--QPMMPVPGQHSM-----------------TPIQHHQPN 118 QP H P QQP PQ +P + HS +P+ H P Sbjct: 1016 GQQPPHP---PPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQ 1072 Query: 119 LPP--------PAQQPYQPQP--------VQPQP---------HQP----------MQPQ 143 + P QQ QP+ VQPQP H P ++P+ Sbjct: 1073 MSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPE 1132 Query: 144 PPVHPMQ-----PLPPQPPLPPMFPMQP-LPPMLPDLTLEAWPSTDKTKRE 188 PP HP LP +P + P+ +P + P + P DK K+E Sbjct: 1133 PPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQE 1183 Score = 41.6 bits (96), Expect = 4e-04 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 14/69 (20%) Query: 114 HHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPD 173 HHQ PA P QP P P QP P PP QP PP PP P +P Sbjct: 742 HHQQMQQAPAPVPQQPPP---PPQQPPPPPPPQQQQQPPPPPPP-----------PSMPQ 787 Query: 174 LTLEAWPST 182 A S+ Sbjct: 788 QAAPAMKSS 796 Score = 40.4 bits (93), Expect = 0.001 Identities = 49/173 (28%), Positives = 57/173 (32%), Gaps = 57/173 (32%) Query: 62 HHQII---PVLSQQHPPTHTLQPHHHIPVVPAQQ----PVIPQQPMMPVPGQHS------ 108 HHQ + P Q PP QP P QQ P P P P S Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801 Query: 109 ---------------MTPIQHH-QP--NLPPPAQQPYQPQPVQ--PQPH----------- 137 PI H QP +LP P P+ PQP + PH Sbjct: 802 ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA 861 Query: 138 ----QPMQPQPPVHPMQPLPPQPPLPP-------MFPMQPLPPML--PDLTLE 177 P QP P + LPP+P PP P+ P PPM P + LE Sbjct: 862 LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLE 914 Score = 35.8 bits (81), Expect = 0.023 Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 24/106 (22%) Query: 71 QQHPPTHTLQPHHHIPVVP---AQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPP-PAQQP 126 Q +PP PH V P Q PV+ P P+ + P QP PP PA QP Sbjct: 212 QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP----QPQPPPAPAPQP 267 Query: 127 YQPQP----VQPQPHQPMQ------------PQPPVHPMQPLPPQP 156 Q P PQP + + P+H LPP+P Sbjct: 268 VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 57.4 bits (137), Expect = 7e-09 Identities = 31/69 (44%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 99 PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL 158 PM P PGQ P PPP QQ QP P QP P QP QPP HP QPP Sbjct: 46 PMGPGPGQSGPKP----PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101 Query: 159 PPMFPMQPL 167 PP +P+ Sbjct: 102 PPQDSSKPV 110 Score = 45.8 bits (107), Expect = 2e-05 Identities = 45/137 (32%), Positives = 48/137 (35%), Gaps = 17/137 (12%) Query: 46 RPPYPSYGYE----PMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMM 101 R P P G PMG P S PP PH P QQP PQQP Sbjct: 32 RSPPPGMGLNQNRGPMGPG------PGQSGPKPPIPPPPPHQQQQQPPPQQPP-PQQPPP 84 Query: 102 PVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ-PQPHQPMQPQPPVHPMQP--LPPQPPL 158 P H P H Q PPP Q +P Q P P + PP P PP Sbjct: 85 HQPPPH---PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141 Query: 159 PPMFPMQPLPPMLPDLT 175 PP P P P +T Sbjct: 142 PPGSGPGPTPTPPPAVT 158 Score = 42.0 bits (97), Expect = 3e-04 Identities = 34/116 (29%), Positives = 37/116 (31%), Gaps = 14/116 (12%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--------- 117 P QQ PP P P P P QQ P P Q S P+ P Sbjct: 65 PHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSA 124 Query: 118 ----NLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169 + PPA P P P P P V P P PP PP + PP Sbjct: 125 PPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP-PPTPPSSGVPTTPP 179 Score = 39.7 bits (91), Expect = 0.002 Identities = 36/111 (32%), Positives = 39/111 (35%), Gaps = 15/111 (13%) Query: 72 QHPPTHTLQPH-----HHIPVVPAQ---QPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPA 123 Q PP H PH P P Q +PV+ Q P P PG S P P PP Sbjct: 80 QQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG-PAPGVGSAPPASSSAPPATPPT 138 Query: 124 Q--QPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQ---PPLPPMFPMQPLPP 169 P P P + PP P P PP P PP P PP Sbjct: 139 SGAPPGSGPGPTPTPPPAVTSAPPGAP-PPTPPSSGVPTTPPQAGGPPPPP 188 Score = 38.5 bits (88), Expect = 0.004 Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 6/61 (9%) Query: 115 HQPNLPPPA------QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168 H PPP + P P P Q P P+ P PP Q PPQ P P P P Sbjct: 29 HDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP 88 Query: 169 P 169 P Sbjct: 89 P 89 Score = 30.8 bits (68), Expect = 0.74 Identities = 26/87 (29%), Positives = 27/87 (31%), Gaps = 5/87 (5%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133 PPT P P P + P PG TP P PP A P P Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSAP----PGAPPPTPPSSGVPTTPPQAGGPPPPPAAV 191 Query: 134 PQPHQ-PMQPQPPVHPMQPLPPQPPLP 159 P P P Q P P P P P Sbjct: 192 PGPGPGPKQGPGPGGPKGGKMPGGPKP 218 >gi|114431236 zinc finger protein 462 [Homo sapiens] Length = 2506 Score = 55.1 bits (131), Expect = 4e-08 Identities = 30/62 (48%), Positives = 34/62 (54%), Gaps = 5/62 (8%) Query: 109 MTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP-VHPMQPLPPQPPLPPMFPMQPL 167 + P+Q QP PPP P P P QPQP Q QPQPP + P +PPQP P QP Sbjct: 534 LDPLQQQQPPQPPPPPPP--PPPSQPQPLQ--QPQPPQLQPPHQVPPQPQTQPPPTQQPQ 589 Query: 168 PP 169 PP Sbjct: 590 PP 591 Score = 44.3 bits (103), Expect = 6e-05 Identities = 32/67 (47%), Positives = 34/67 (50%), Gaps = 7/67 (10%) Query: 89 PAQQPVIPQQPMMPVPGQHSMT-PIQHHQP-NLPPPAQQPYQPQPVQPQPHQPMQPQPPV 146 P QQ PQ P P P S P+Q QP L PP Q P QPQ QP P Q QPQPP Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQ-TQPPPTQ--QPQPPT 592 Query: 147 H--PMQP 151 P+ P Sbjct: 593 QAAPLHP 599 Score = 43.5 bits (101), Expect = 1e-04 Identities = 28/67 (41%), Positives = 31/67 (46%), Gaps = 13/67 (19%) Query: 93 PVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQ-QP-YQPQPVQPQPHQPMQPQPPVHPMQ 150 P+ QQP P P P PPP+Q QP QPQP Q QP + PQP P Sbjct: 536 PLQQQQPPQPPP-----------PPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPP 584 Query: 151 PLPPQPP 157 PQPP Sbjct: 585 TQQPQPP 591 Score = 36.2 bits (82), Expect = 0.018 Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 11/88 (12%) Query: 51 SYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMP-VPGQHSM 109 SY + G ++ L QQ PP QP P P QP QQP P + H + Sbjct: 519 SYESSSINGRKSGVMLDPLQQQQPP----QPPPPPPPPPPSQPQPLQQPQPPQLQPPHQV 574 Query: 110 TPIQHHQPNLPPPAQQPYQP---QPVQP 134 P QP PP QQP P P+ P Sbjct: 575 PPQPQTQP---PPTQQPQPPTQAAPLHP 599 Score = 36.2 bits (82), Expect = 0.018 Identities = 16/33 (48%), Positives = 17/33 (51%) Query: 139 PMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPML 171 P+Q Q P P P PP PP P QP PP L Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQL 568 Score = 33.5 bits (75), Expect = 0.11 Identities = 26/68 (38%), Positives = 30/68 (44%), Gaps = 9/68 (13%) Query: 35 VLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV 94 +L PL+ Q +PP P P Q P L Q PP LQP H +P P QP Sbjct: 533 MLDPLQQQQPPQPPPPPPPPPPS------QPQP-LQQPQPPQ--LQPPHQVPPQPQTQPP 583 Query: 95 IPQQPMMP 102 QQP P Sbjct: 584 PTQQPQPP 591 Score = 33.5 bits (75), Expect = 0.11 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 7/55 (12%) Query: 135 QPHQPMQPQPPVHPMQPLPPQP---PLPPMF----PMQPLPPMLPDLTLEAWPST 182 Q QP QP PP P P PQP P PP + P P P T + P T Sbjct: 538 QQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPT 592 Score = 29.6 bits (65), Expect = 1.7 Identities = 13/28 (46%), Positives = 14/28 (50%) Query: 145 PVHPMQPLPPQPPLPPMFPMQPLPPMLP 172 P+ QP P PP PP P QP P P Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQP 563 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 54.7 bits (130), Expect = 5e-08 Identities = 50/186 (26%), Positives = 65/186 (34%), Gaps = 20/186 (10%) Query: 18 PLPPHPGHPGYINFSYEVLTPLKWYQSIR-------------PPYPSYGYEPMGGWLHHQ 64 P P GH GY Y TP ++ +++ P YG + G+ Sbjct: 408 PSGPQQGH-GYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQG 466 Query: 65 IIPVLSQQHP-PTHTLQPHHHIPV--VPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPP 121 P +QQ P P P+ P P QP QQP P S P QP+ PP Sbjct: 467 QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 Query: 122 PAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181 Q P Q Q Q QPP Q Q P P QP P L P Sbjct: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQ---AQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 Query: 182 TDKTKR 187 + ++++ Sbjct: 584 SQQSQQ 589 Score = 45.8 bits (107), Expect = 2e-05 Identities = 45/161 (27%), Positives = 57/161 (35%), Gaps = 21/161 (13%) Query: 12 GAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPY--PSYGYEPMGGWLHHQII--- 66 G ++ +PP+ G G + + TP QS P P Y +P H Q Sbjct: 444 GLSYTQQIPPY-GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502 Query: 67 ------PVLSQQHPPTH---TLQPHHHIPV-VPAQQPVIPQQPMM--PVPGQHSMTPIQH 114 P L PP + PH P P+QQ Q P P + +P Q Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562 Query: 115 HQPNLPPP---AQQPYQPQPVQPQPHQPMQPQPPVHPMQPL 152 QP P P +QQ PQP Q Q Q P Q L Sbjct: 563 QQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603 Score = 32.0 bits (71), Expect = 0.33 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 13/84 (15%) Query: 89 PAQQPVIPQQPMM-PVPGQHSMTP-IQHHQPNLPPPAQQPYQPQPVQPQP------HQPM 140 P P P PM P P + P +Q+H P + PA P +P + P H M Sbjct: 1553 PPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLP-RPMENRTSPSKSPFLHSGM 1611 Query: 141 QPQ---PPVHPMQPLPPQPPLPPM 161 + Q PPV P + P P PPM Sbjct: 1612 KMQKAGPPV-PASHIAPAPVQPPM 1634 Score = 29.6 bits (65), Expect = 1.7 Identities = 26/92 (28%), Positives = 35/92 (38%), Gaps = 17/92 (18%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 PV PP QP P+ Q IPQ S P+ N P++ P Sbjct: 1560 PVPPMTRPPPSNYQPP------PSMQNHIPQVS--------SPAPLPRPMENRTSPSKSP 1605 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL 158 + ++ Q P P P H + P P QPP+ Sbjct: 1606 FLHSGMKMQKAGP--PVPASH-IAPAPVQPPM 1634 Score = 28.5 bits (62), Expect = 3.7 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 11/70 (15%) Query: 114 HHQPNLPPPAQQPYQPQPVQPQPHQP------MQPQP-----PVHPMQPLPPQPPLPPMF 162 HH P P + QP PQP P M+PQP P Q P P + Sbjct: 358 HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGY 417 Query: 163 PMQPLPPMLP 172 P QP P Sbjct: 418 PGQPYGSQTP 427 Score = 28.1 bits (61), Expect = 4.8 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 7/64 (10%) Query: 89 PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQ-------PYQPQPVQPQPHQPMQ 141 P +P M P P I H N AQ P PQ PQP + Sbjct: 713 PLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS 772 Query: 142 PQPP 145 P+ P Sbjct: 773 PRQP 776 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 54.7 bits (130), Expect = 5e-08 Identities = 50/186 (26%), Positives = 65/186 (34%), Gaps = 20/186 (10%) Query: 18 PLPPHPGHPGYINFSYEVLTPLKWYQSIR-------------PPYPSYGYEPMGGWLHHQ 64 P P GH GY Y TP ++ +++ P YG + G+ Sbjct: 408 PSGPQQGH-GYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQG 466 Query: 65 IIPVLSQQHP-PTHTLQPHHHIPV--VPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPP 121 P +QQ P P P+ P P QP QQP P S P QP+ PP Sbjct: 467 QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 Query: 122 PAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181 Q P Q Q Q QPP Q Q P P QP P L P Sbjct: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQ---AQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 Query: 182 TDKTKR 187 + ++++ Sbjct: 584 SQQSQQ 589 Score = 45.8 bits (107), Expect = 2e-05 Identities = 45/161 (27%), Positives = 57/161 (35%), Gaps = 21/161 (13%) Query: 12 GAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPY--PSYGYEPMGGWLHHQII--- 66 G ++ +PP+ G G + + TP QS P P Y +P H Q Sbjct: 444 GLSYTQQIPPY-GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502 Query: 67 ------PVLSQQHPPTH---TLQPHHHIPV-VPAQQPVIPQQPMM--PVPGQHSMTPIQH 114 P L PP + PH P P+QQ Q P P + +P Q Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562 Query: 115 HQPNLPPP---AQQPYQPQPVQPQPHQPMQPQPPVHPMQPL 152 QP P P +QQ PQP Q Q Q P Q L Sbjct: 563 QQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603 Score = 28.5 bits (62), Expect = 3.7 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 11/70 (15%) Query: 114 HHQPNLPPPAQQPYQPQPVQPQPHQP------MQPQP-----PVHPMQPLPPQPPLPPMF 162 HH P P + QP PQP P M+PQP P Q P P + Sbjct: 358 HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGY 417 Query: 163 PMQPLPPMLP 172 P QP P Sbjct: 418 PGQPYGSQTP 427 Score = 28.1 bits (61), Expect = 4.8 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 7/64 (10%) Query: 89 PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQ-------PYQPQPVQPQPHQPMQ 141 P +P M P P I H N AQ P PQ PQP + Sbjct: 713 PLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS 772 Query: 142 PQPP 145 P+ P Sbjct: 773 PRQP 776 Score = 28.1 bits (61), Expect = 4.8 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 7/66 (10%) Query: 102 PVPGQHSMTPIQHHQPNLPPPAQQPYQPQPV---QPQPHQPMQPQ---PPVHPMQPLPPQ 155 P P Q + Q Q + P P +P + + P H M+ Q PPV P + P Sbjct: 1353 PFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV-PASHIAPA 1411 Query: 156 PPLPPM 161 P PPM Sbjct: 1412 PVQPPM 1417 Score = 27.3 bits (59), Expect = 8.2 Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 7/70 (10%) Query: 89 PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP 148 P+QQ + QQ S P+ N P++ P+ ++ Q P P P H Sbjct: 1355 PSQQTTMYQQQQQV----SSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGP--PVPASH- 1407 Query: 149 MQPLPPQPPL 158 + P P QPP+ Sbjct: 1408 IAPAPVQPPM 1417 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 54.3 bits (129), Expect = 6e-08 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Query: 87 VVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--NLPPPAQQPYQPQ-PVQPQPHQPMQPQ 143 V PA P P +P PG TP P P +Q P QPQ P P PH +Q Sbjct: 193 VTPAPSSAPPGTPQLPTPGP---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 249 Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPM 170 P +HP +P P PP P P PL P+ Sbjct: 250 PALHPQRPPSPHPP-PHPSPHPPLQPL 275 Score = 47.4 bits (111), Expect = 8e-06 Identities = 40/110 (36%), Positives = 44/110 (40%), Gaps = 16/110 (14%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQH-SMTPIQHHQ-PNLPPPAQQPYQPQPV 132 P+ T P P +Q P PQ P PVP H P H Q P P P P P+ Sbjct: 214 PSATAVPPQGSPTA-SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 272 Query: 133 QP------QPHQPMQPQPPVHPMQPLPPQ-----PPLPPMFPMQP--LPP 169 QP QP P QPP+H P P P L P QP LPP Sbjct: 273 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322 Score = 47.4 bits (111), Expect = 8e-06 Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 16/125 (12%) Query: 74 PPTHTL------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQ-HHQPNL-PPPAQQ 125 PPT + Q H H P + P + P P ++ + HH P+ PPP Q Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 436 Query: 126 PYQPQPVQPQPHQP--------MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177 Q QP+ P QP + P P HP L P PP +P P +T Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 496 Query: 178 AWPST 182 PST Sbjct: 497 TCPST 501 Score = 47.0 bits (110), Expect = 1e-05 Identities = 32/100 (32%), Positives = 38/100 (38%), Gaps = 10/100 (10%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134 P +L HH P ++PQ P+P + P NLPPP P P Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQSQNLPPP------PASHPP 468 Query: 135 QPHQPMQPQPPV--HPMQPLPPQPPLPPMFPMQPLPPMLP 172 + PQPP HP P P P PP P PP P Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 508 Score = 45.4 bits (106), Expect = 3e-05 Identities = 53/181 (29%), Positives = 63/181 (34%), Gaps = 51/181 (28%) Query: 16 AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMG-----GWLHHQI-IPV- 68 A PL HPG P PP S G P+G + H + +P Sbjct: 305 AGPLLQHPGPPQPFGL---------------PPQASQGQAPLGTSPAAAYPHTSLQLPAS 349 Query: 69 ---LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL------ 119 L Q PP QP +P P P I P P+P Q H P+L Sbjct: 350 QSALQSQQPPRE--QP---LPPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPF 403 Query: 120 -------PPPAQQPYQPQPVQPQPHQPMQPQPPVHPM---QPLPPQPPLPP-MFPMQPLP 168 PPPA +P H P PP+ M QPLP P PP + Q LP Sbjct: 404 SMNANLPPPPALKPLSSLSTH---HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 460 Query: 169 P 169 P Sbjct: 461 P 461 Score = 42.0 bits (97), Expect = 3e-04 Identities = 44/143 (30%), Positives = 50/143 (34%), Gaps = 39/143 (27%) Query: 62 HHQIIPVLSQQHPPTHTLQPHH--HIPVVP----AQQPVIPQQPMMPVPGQHSMTPIQHH 115 H Q P L Q PP+ PH H P+ P A QP P P+ GQ P H Sbjct: 245 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---H 301 Query: 116 QPNLPPPAQQPYQPQP--VQPQ----------------PHQPMQ----------PQPPVH 147 P Q P PQP + PQ PH +Q QPP Sbjct: 302 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 361 Query: 148 PMQPLPPQPPLPPMFPMQPLPPM 170 QPLPP P P P P+ Sbjct: 362 --QPLPPAPLAMPHIKPPPTTPI 382 Score = 42.0 bits (97), Expect = 3e-04 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 9/90 (10%) Query: 73 HPPTHTLQPHHH-IPVVPAQQPVIPQ-QPMMPVPGQHSMTPIQHHQPNLPPPAQQPY--- 127 HPP L P +P PAQ P + Q Q + P P H T + P PP AQ P+ Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ-PPFAQHPFVPG 488 Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P+ P P P PP P QPP Sbjct: 489 GPPPITP-PTCPSTSTPPAGP--GTSAQPP 515 Score = 41.2 bits (95), Expect = 5e-04 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 18/125 (14%) Query: 47 PPYPSYGYEPMGGWLHHQIIPVLSQ--QHPPTHTLQ-PHHHIPVVPAQQPVIPQQPMMPV 103 P P+ G P + Q P SQ P T PH HI PA P Q+P P Sbjct: 205 PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP---QRPPSPH 261 Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ-------PLPPQP 156 P H +P QP L A QP P QP H P P H +Q P PPQP Sbjct: 262 PPPHP-SPHPPLQP-LTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQAGPLLQHPGPPQP 317 Query: 157 -PLPP 160 LPP Sbjct: 318 FGLPP 322 Score = 37.0 bits (84), Expect = 0.010 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 37/175 (21%) Query: 20 PPHPG-HPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW-----LHHQIIPVLSQQH 73 PPHP HP L PL +P PS+ P+ G Q P+L Sbjct: 263 PPHPSPHPP--------LQPLTGSAG-QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313 Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP-----IQHHQPNLPPPAQQPYQ 128 PP QP P Q + P P P +Q Q PP +QP Sbjct: 314 PP----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ----PPREQPLP 365 Query: 129 PQP-----VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQ---PLPPMLPDLT 175 P P ++P P P+ PQ P PP P F M P PP L L+ Sbjct: 366 PAPLAMPHIKPPPTTPI-PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLS 419 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 54.3 bits (129), Expect = 6e-08 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Query: 87 VVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--NLPPPAQQPYQPQ-PVQPQPHQPMQPQ 143 V PA P P +P PG TP P P +Q P QPQ P P PH +Q Sbjct: 747 VTPAPSSAPPGTPQLPTPGP---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 803 Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPM 170 P +HP +P P PP P P PL P+ Sbjct: 804 PALHPQRPPSPHPP-PHPSPHPPLQPL 829 Score = 47.4 bits (111), Expect = 8e-06 Identities = 40/110 (36%), Positives = 44/110 (40%), Gaps = 16/110 (14%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQH-SMTPIQHHQ-PNLPPPAQQPYQPQPV 132 P+ T P P +Q P PQ P PVP H P H Q P P P P P+ Sbjct: 768 PSATAVPPQGSPTA-SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826 Query: 133 QP------QPHQPMQPQPPVHPMQPLPPQ-----PPLPPMFPMQP--LPP 169 QP QP P QPP+H P P P L P QP LPP Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876 Score = 47.4 bits (111), Expect = 8e-06 Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 16/125 (12%) Query: 74 PPTHTL------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQ-HHQPNL-PPPAQQ 125 PPT + Q H H P + P + P P ++ + HH P+ PPP Q Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 990 Query: 126 PYQPQPVQPQPHQP--------MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177 Q QP+ P QP + P P HP L P PP +P P +T Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050 Query: 178 AWPST 182 PST Sbjct: 1051 TCPST 1055 Score = 47.0 bits (110), Expect = 1e-05 Identities = 32/100 (32%), Positives = 38/100 (38%), Gaps = 10/100 (10%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134 P +L HH P ++PQ P+P + P NLPPP P P Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQSQNLPPP------PASHPP 1022 Query: 135 QPHQPMQPQPPV--HPMQPLPPQPPLPPMFPMQPLPPMLP 172 + PQPP HP P P P PP P PP P Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 1062 Score = 45.4 bits (106), Expect = 3e-05 Identities = 53/181 (29%), Positives = 63/181 (34%), Gaps = 51/181 (28%) Query: 16 AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMG-----GWLHHQI-IPV- 68 A PL HPG P PP S G P+G + H + +P Sbjct: 859 AGPLLQHPGPPQPFGL---------------PPQASQGQAPLGTSPAAAYPHTSLQLPAS 903 Query: 69 ---LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL------ 119 L Q PP QP +P P P I P P+P Q H P+L Sbjct: 904 QSALQSQQPPRE--QP---LPPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPF 957 Query: 120 -------PPPAQQPYQPQPVQPQPHQPMQPQPPVHPM---QPLPPQPPLPP-MFPMQPLP 168 PPPA +P H P PP+ M QPLP P PP + Q LP Sbjct: 958 SMNANLPPPPALKPLSSLSTH---HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 1014 Query: 169 P 169 P Sbjct: 1015 P 1015 Score = 42.0 bits (97), Expect = 3e-04 Identities = 44/143 (30%), Positives = 50/143 (34%), Gaps = 39/143 (27%) Query: 62 HHQIIPVLSQQHPPTHTLQPHH--HIPVVP----AQQPVIPQQPMMPVPGQHSMTPIQHH 115 H Q P L Q PP+ PH H P+ P A QP P P+ GQ P H Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---H 855 Query: 116 QPNLPPPAQQPYQPQP--VQPQ----------------PHQPMQ----------PQPPVH 147 P Q P PQP + PQ PH +Q QPP Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915 Query: 148 PMQPLPPQPPLPPMFPMQPLPPM 170 QPLPP P P P P+ Sbjct: 916 --QPLPPAPLAMPHIKPPPTTPI 936 Score = 42.0 bits (97), Expect = 3e-04 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 9/90 (10%) Query: 73 HPPTHTLQPHHH-IPVVPAQQPVIPQ-QPMMPVPGQHSMTPIQHHQPNLPPPAQQPY--- 127 HPP L P +P PAQ P + Q Q + P P H T + P PP AQ P+ Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ-PPFAQHPFVPG 1042 Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P+ P P P PP P QPP Sbjct: 1043 GPPPITP-PTCPSTSTPPAGP--GTSAQPP 1069 Score = 41.2 bits (95), Expect = 5e-04 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 18/125 (14%) Query: 47 PPYPSYGYEPMGGWLHHQIIPVLSQ--QHPPTHTLQ-PHHHIPVVPAQQPVIPQQPMMPV 103 P P+ G P + Q P SQ P T PH HI PA P Q+P P Sbjct: 759 PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP---QRPPSPH 815 Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ-------PLPPQP 156 P H +P QP L A QP P QP H P P H +Q P PPQP Sbjct: 816 PPPHP-SPHPPLQP-LTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQAGPLLQHPGPPQP 871 Query: 157 -PLPP 160 LPP Sbjct: 872 FGLPP 876 Score = 37.0 bits (84), Expect = 0.010 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 37/175 (21%) Query: 20 PPHPG-HPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW-----LHHQIIPVLSQQH 73 PPHP HP L PL +P PS+ P+ G Q P+L Sbjct: 817 PPHPSPHPP--------LQPLTGSAG-QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867 Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP-----IQHHQPNLPPPAQQPYQ 128 PP QP P Q + P P P +Q Q PP +QP Sbjct: 868 PP----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ----PPREQPLP 919 Query: 129 PQP-----VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQ---PLPPMLPDLT 175 P P ++P P P+ PQ P PP P F M P PP L L+ Sbjct: 920 PAPLAMPHIKPPPTTPI-PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLS 973 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 54.3 bits (129), Expect = 6e-08 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Query: 87 VVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--NLPPPAQQPYQPQ-PVQPQPHQPMQPQ 143 V PA P P +P PG TP P P +Q P QPQ P P PH +Q Sbjct: 747 VTPAPSSAPPGTPQLPTPGP---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 803 Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPM 170 P +HP +P P PP P P PL P+ Sbjct: 804 PALHPQRPPSPHPP-PHPSPHPPLQPL 829 Score = 47.4 bits (111), Expect = 8e-06 Identities = 40/110 (36%), Positives = 44/110 (40%), Gaps = 16/110 (14%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQH-SMTPIQHHQ-PNLPPPAQQPYQPQPV 132 P+ T P P +Q P PQ P PVP H P H Q P P P P P+ Sbjct: 768 PSATAVPPQGSPTA-SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826 Query: 133 QP------QPHQPMQPQPPVHPMQPLPPQ-----PPLPPMFPMQP--LPP 169 QP QP P QPP+H P P P L P QP LPP Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876 Score = 47.4 bits (111), Expect = 8e-06 Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 16/125 (12%) Query: 74 PPTHTL------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQ-HHQPNL-PPPAQQ 125 PPT + Q H H P + P + P P ++ + HH P+ PPP Q Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 990 Query: 126 PYQPQPVQPQPHQP--------MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177 Q QP+ P QP + P P HP L P PP +P P +T Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050 Query: 178 AWPST 182 PST Sbjct: 1051 TCPST 1055 Score = 47.0 bits (110), Expect = 1e-05 Identities = 32/100 (32%), Positives = 38/100 (38%), Gaps = 10/100 (10%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134 P +L HH P ++PQ P+P + P NLPPP P P Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQSQNLPPP------PASHPP 1022 Query: 135 QPHQPMQPQPPV--HPMQPLPPQPPLPPMFPMQPLPPMLP 172 + PQPP HP P P P PP P PP P Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 1062 Score = 45.4 bits (106), Expect = 3e-05 Identities = 53/181 (29%), Positives = 63/181 (34%), Gaps = 51/181 (28%) Query: 16 AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMG-----GWLHHQI-IPV- 68 A PL HPG P PP S G P+G + H + +P Sbjct: 859 AGPLLQHPGPPQPFGL---------------PPQASQGQAPLGTSPAAAYPHTSLQLPAS 903 Query: 69 ---LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL------ 119 L Q PP QP +P P P I P P+P Q H P+L Sbjct: 904 QSALQSQQPPRE--QP---LPPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPF 957 Query: 120 -------PPPAQQPYQPQPVQPQPHQPMQPQPPVHPM---QPLPPQPPLPP-MFPMQPLP 168 PPPA +P H P PP+ M QPLP P PP + Q LP Sbjct: 958 SMNANLPPPPALKPLSSLSTH---HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 1014 Query: 169 P 169 P Sbjct: 1015 P 1015 Score = 42.0 bits (97), Expect = 3e-04 Identities = 44/143 (30%), Positives = 50/143 (34%), Gaps = 39/143 (27%) Query: 62 HHQIIPVLSQQHPPTHTLQPHH--HIPVVP----AQQPVIPQQPMMPVPGQHSMTPIQHH 115 H Q P L Q PP+ PH H P+ P A QP P P+ GQ P H Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---H 855 Query: 116 QPNLPPPAQQPYQPQP--VQPQ----------------PHQPMQ----------PQPPVH 147 P Q P PQP + PQ PH +Q QPP Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915 Query: 148 PMQPLPPQPPLPPMFPMQPLPPM 170 QPLPP P P P P+ Sbjct: 916 --QPLPPAPLAMPHIKPPPTTPI 936 Score = 42.0 bits (97), Expect = 3e-04 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 9/90 (10%) Query: 73 HPPTHTLQPHHH-IPVVPAQQPVIPQ-QPMMPVPGQHSMTPIQHHQPNLPPPAQQPY--- 127 HPP L P +P PAQ P + Q Q + P P H T + P PP AQ P+ Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ-PPFAQHPFVPG 1042 Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157 P P+ P P P PP P QPP Sbjct: 1043 GPPPITP-PTCPSTSTPPAGP--GTSAQPP 1069 Score = 41.2 bits (95), Expect = 5e-04 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 18/125 (14%) Query: 47 PPYPSYGYEPMGGWLHHQIIPVLSQ--QHPPTHTLQ-PHHHIPVVPAQQPVIPQQPMMPV 103 P P+ G P + Q P SQ P T PH HI PA P Q+P P Sbjct: 759 PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP---QRPPSPH 815 Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ-------PLPPQP 156 P H +P QP L A QP P QP H P P H +Q P PPQP Sbjct: 816 PPPHP-SPHPPLQP-LTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQAGPLLQHPGPPQP 871 Query: 157 -PLPP 160 LPP Sbjct: 872 FGLPP 876 Score = 37.0 bits (84), Expect = 0.010 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 37/175 (21%) Query: 20 PPHPG-HPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW-----LHHQIIPVLSQQH 73 PPHP HP L PL +P PS+ P+ G Q P+L Sbjct: 817 PPHPSPHPP--------LQPLTGSAG-QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867 Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP-----IQHHQPNLPPPAQQPYQ 128 PP QP P Q + P P P +Q Q PP +QP Sbjct: 868 PP----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ----PPREQPLP 919 Query: 129 PQP-----VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQ---PLPPMLPDLT 175 P P ++P P P+ PQ P PP P F M P PP L L+ Sbjct: 920 PAPLAMPHIKPPPTTPI-PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLS 973 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 54.3 bits (129), Expect = 6e-08 Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 12/137 (8%) Query: 38 PLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQ 97 P Y + PP P+ + L ++P P + P PV+P P Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP----PVMPPSLPTSVP 574 Query: 98 QPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL---PP 154 P MP P S P P LPPP+ P PV P P PPV P+ PL P Sbjct: 575 PPGMP-PSLSSAGP----PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP 629 Query: 155 QPPLPPMFPMQPLPPML 171 P +PP Q +PP L Sbjct: 630 PPGIPPPGVPQGIPPQL 646 Score = 51.6 bits (122), Expect = 4e-07 Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 19/134 (14%) Query: 44 SIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPV 103 S+ PP+ Y P P L PP L P PV+P P P MP Sbjct: 515 SMPPPFVPYSQMP----------PPLPTMPPPV--LPPSLPPPVMPPALPATVPPPGMPP 562 Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL-----PPQPPL 158 P P P +PP P PV P P PPV P L PP PL Sbjct: 563 PVMPPSLPTSVPPPGMPPSLSSA-GPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPL 621 Query: 159 PPMFPMQPLPPMLP 172 PP+ P PP +P Sbjct: 622 PPLSSATP-PPGIP 634 Score = 44.7 bits (104), Expect = 5e-05 Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 34/124 (27%) Query: 79 LQPHHHIPVVPAQQPVI-----------PQQPMMPVPG--------QHSMTPIQHHQPNL 119 LQPHH +P P P + P PM P PG Q + HHQ + Sbjct: 76 LQPHH-LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134 Query: 120 PP-----PAQQPYQPQPVQPQPHQPMQ------PQPPVHPMQPLPPQPPLPPMFPMQPLP 168 PP + P + PV P + P PQPP P QP LP P QP P Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP---PAQPSP 191 Query: 169 PMLP 172 P Sbjct: 192 SQSP 195 Score = 43.5 bits (101), Expect = 1e-04 Identities = 45/164 (27%), Positives = 57/164 (34%), Gaps = 31/164 (18%) Query: 20 PPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTL 79 P P G+++F + L L+ Q + Q+ VL H P L Sbjct: 42 PAAPSSSGFMSFREQHLAQLQQLQQMH---------------QKQMQCVLQPHHLPPPPL 86 Query: 80 QPHHHIPVVPAQ-----QPVIPQQPMMPVPG------QHSMTPIQHHQPNLPPPAQQPYQ 128 P PV+P QP P P P P Q + HHQ + PP Sbjct: 87 PPP---PVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMEL 143 Query: 129 PQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172 P + P P PP P PPQPP P +P P LP Sbjct: 144 ESPPESPPVPPGSYMPPSQSYMP-PPQPP-PSYYPPTSSQPYLP 185 Score = 43.5 bits (101), Expect = 1e-04 Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 15/94 (15%) Query: 86 PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP 145 P VP Q + P P MP P + P P+LPPP P P V P P P P Sbjct: 519 PFVPYSQ-MPPPLPTMPPP----VLP-----PSLPPPVMPPALPATVPP----PGMPPPV 564 Query: 146 VHPMQPLPPQPP-LPPMFPMQPLPPMLPDLTLEA 178 + P P PP +PP PP+LP +L + Sbjct: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSS 598 Score = 39.7 bits (91), Expect = 0.002 Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 7/64 (10%) Query: 117 PNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTL 176 P +PPP P P PV P P P PP +PP P +PP P PP +P Sbjct: 531 PTMPPPVLPPSLPPPVMP-PALPATVPPP-----GMPP-PVMPPSLPTSVPPPGMPPSLS 583 Query: 177 EAWP 180 A P Sbjct: 584 SAGP 587 Score = 39.3 bits (90), Expect = 0.002 Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 103 VPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP--------VHPMQPLPP 154 +P Q S +P + PP P P+ P ++P P P P+PP Sbjct: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548 Query: 155 QPPLPPMFPMQP-LPPMLPDLTLEAW 179 PP PP+ P P + P + E W Sbjct: 1549 PPPPPPLPPPPPVIKPQTSAVEQERW 1574 Score = 37.4 bits (85), Expect = 0.008 Identities = 40/166 (24%), Positives = 56/166 (33%), Gaps = 24/166 (14%) Query: 26 PGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHI 85 P Y + S + L QS P + P G Q++ PP + Sbjct: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP 264 Query: 86 PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQ---------------PNLPPPAQQPY--- 127 A+ QQ P P +MTP + Q +LP + P Sbjct: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324 Query: 128 -QPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172 P+PV+ + P Q P P PP PP P + +PP LP Sbjct: 325 DTPEPVKEEVTVPATSQVPESPSSEEPPLPP-----PNEEVPPPLP 365 Score = 33.5 bits (75), Expect = 0.11 Identities = 32/98 (32%), Positives = 39/98 (39%), Gaps = 20/98 (20%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P LS PP L P P+ P P+MP+P S TP P +PPP Sbjct: 594 PSLSSAGPPP-VLPP-------PSLSSTAPP-PVMPLPPLSSATP----PPGIPPPG--- 637 Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP-PQPPLPPMFP 163 PQ + PQ P PP Q P+ P P + P Sbjct: 638 -VPQGIPPQ--LTAAPVPPASSSQSSQVPEKPRPALLP 672 Score = 32.7 bits (73), Expect = 0.20 Identities = 17/46 (36%), Positives = 18/46 (39%), Gaps = 3/46 (6%) Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172 Y P P P PP P P P LPP P +PP LP Sbjct: 510 YMGNMSMPPPFVPYSQMPPPLPTM---PPPVLPPSLPPPVMPPALP 552 Score = 31.2 bits (69), Expect = 0.57 Identities = 34/105 (32%), Positives = 43/105 (40%), Gaps = 23/105 (21%) Query: 82 HHHIPVVPAQQPV-IPQQPMMPVPGQHSMTPIQHHQPNLPPPA-------QQPYQPQPVQ 133 H+ P VP PV +P+ P PG S T P P + Q Q Q +Q Sbjct: 13 HYPPPPVPPPPPVALPEAS--PGPGYSSSTT-----PAAPSSSGFMSFREQHLAQLQQLQ 65 Query: 134 PQPHQPMQPQPPVHPMQPLPPQPPLPPMFP------MQPLPPMLP 172 + MQ H + P PP PP PP+ P QP PP +P Sbjct: 66 QMHQKQMQCVLQPHHLPP-PPLPP-PPVMPGGGYGDWQPPPPPMP 108 Score = 30.8 bits (68), Expect = 0.74 Identities = 24/83 (28%), Positives = 28/83 (33%), Gaps = 4/83 (4%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVP----GQHSMTPIQHHQPNLPPPAQQPYQP 129 PP + P IP Q + PQ PVP Q S P + LP P P Sbjct: 622 PPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAP 681 Query: 130 QPVQPQPHQPMQPQPPVHPMQPL 152 P Q P V+ PL Sbjct: 682 PTTYHPPLQSAGPSEQVNSKAPL 704 Score = 30.8 bits (68), Expect = 0.74 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%) Query: 136 PHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169 P P+ P PPVH +PP P+P P PP Sbjct: 1603 PSAPVLPPPPVH--SSIPPPGPVPMGMPPMSKPP 1634 Score = 30.4 bits (67), Expect = 0.97 Identities = 39/174 (22%), Positives = 59/174 (33%), Gaps = 48/174 (27%) Query: 18 PLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW----LHHQ------IIP 67 PLPP P PG ++ P PP P+ Y+ + LHHQ ++P Sbjct: 85 PLPPPPVMPGGGYGDWQPPPP----PMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140 Query: 68 VLSQQHPPTHTLQPHHHIPVV----------PAQQPVIPQQPMMPV---------PGQHS 108 + + P + + P ++P P+ P QP +P P Q Sbjct: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200 Query: 109 MTP--------------IQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP 148 + P + H Q LP P +P + Q + P PP P Sbjct: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSK-SQLLAPPPPSAP 253 Score = 29.3 bits (64), Expect = 2.2 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 6/82 (7%) Query: 60 WLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV-IPQQPMMPVPGQHSMTPIQHHQPN 118 W ++ + QQ H L H PVV P + ++ +P Q +P +P Sbjct: 297 WYRQHLLSL--QQRTKVH-LPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESP-SSEEPP 352 Query: 119 LPPPAQQPYQP-QPVQPQPHQP 139 LPPP ++ P P +PQ P Sbjct: 353 LPPPNEEVPPPLPPEEPQSEDP 374 Score = 27.7 bits (60), Expect = 6.3 Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 138 QPMQPQPPVHPMQPLPPQPPLPPMFPMQPL 167 +P+ Q + +P PPLPP+ P+ PL Sbjct: 1314 RPLDEQESQFRERDIPSLPPLPPLPPLPPL 1343 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 53.9 bits (128), Expect = 8e-08 Identities = 47/169 (27%), Positives = 62/169 (36%), Gaps = 29/169 (17%) Query: 18 PLPPHPGHPGYINFSYEVLTPLKW-----YQSIRPPY----PSYGYEPMGGWLHHQIIPV 68 PLP P P ++ + T + YQS++ PSYG P Sbjct: 415 PLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPA---------- 464 Query: 69 LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQ-----PMMPVPGQHSMTPIQHHQPNLPPPA 123 PP H H P P PV P P +P P P + PN PPP Sbjct: 465 ---YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPP 521 Query: 124 QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPP--QPPLPPMFPMQPLPPM 170 + V P P + P +P +PP QPP+PP P +PP+ Sbjct: 522 PRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570 Score = 48.1 bits (113), Expect = 4e-06 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 21/111 (18%) Query: 74 PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133 PP + P H+P P P P P +P P P P +PPP Y P P Sbjct: 462 PPAYG--PPAHLPYHPHVYPPNPPPPPVPPP------PASFPPPAIPPPTPG-YPPPPPT 512 Query: 134 PQPHQPMQPQ--PPVHPMQPLPPQ----------PPLPPMFPMQPLPPMLP 172 P+ P P PP H + P PP PP P P+PP +P Sbjct: 513 YNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIP 563 Score = 43.1 bits (100), Expect = 1e-04 Identities = 48/151 (31%), Positives = 56/151 (37%), Gaps = 48/151 (31%) Query: 63 HQIIPVLSQ--QHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120 HQI+ + SQ Q P HT H + P+ QP PQ P +Q QP+ Sbjct: 252 HQILDLYSQGKQQMPHHT---PHQLQQPPSLQPT-PQVPQ-----------VQQSQPSQS 296 Query: 121 PPAQQPYQPQPVQP----QP-HQPMQPQP-PVHPMQ-----------------PLPPQ-- 155 QP Q P QP QP QP +P P P P Q P PP+ Sbjct: 297 SEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIP 356 Query: 156 ------PPLPPMFPMQPLPPMLPDLTLEAWP 180 PPLPP P P L EA P Sbjct: 357 KIETTHPPLPPAHPPPDRKPPLAAALGEAEP 387 Score = 40.0 bits (92), Expect = 0.001 Identities = 34/118 (28%), Positives = 41/118 (34%), Gaps = 15/118 (12%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 PV + P P H PV Q P +P +P P P + MT + + Q Sbjct: 390 PVDATDLPKVQIPPPAHPAPV--HQPPPLPHRPPPPPPSSY-MTGMSTTSSYMSGEGYQS 446 Query: 127 YQPQPVQPQPHQPMQPQ---PPVH---------PMQPLPPQPPLPPMFPMQPLPPMLP 172 Q P P PP H P P PP PP P FP +PP P Sbjct: 447 LQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP 504 Score = 37.0 bits (84), Expect = 0.010 Identities = 37/140 (26%), Positives = 48/140 (34%), Gaps = 45/140 (32%) Query: 66 IPVLSQQHPP--THTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHS--------------- 108 +P + Q P + QP P PAQQ QQP P P S Sbjct: 285 VPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEE 344 Query: 109 ----------MTPIQHHQPNLPPPAQQPYQPQPV-----QPQPHQPMQ---------PQP 144 + I+ P LPP P + P+ + +P P+ P P Sbjct: 345 NKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPP 404 Query: 145 ----PVHPMQPLPPQPPLPP 160 PVH PLP +PP PP Sbjct: 405 AHPAPVHQPPPLPHRPPPPP 424 >gi|5174545 myocyte enhancer factor 2D [Homo sapiens] Length = 521 Score = 52.8 bits (125), Expect = 2e-07 Identities = 36/89 (40%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 99 PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP--PVHPMQPLPPQP 156 P PG S+ + Q P QQP QPQP Q QP QP QPQP P P QP Q Sbjct: 348 PAFSSPGGLSLGNVTAWQQ--PQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQS 405 Query: 157 PLPP-----MFPMQPLPPMLPDLTLEAWP 180 L P + P PLP + LT+ P Sbjct: 406 HLVPVSLSNLIPGSPLPHVGAALTVTTHP 434 Score = 42.0 bits (97), Expect = 3e-04 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 6/96 (6%) Query: 71 QQHPPTHTLQPHHHIPVVPAQ-QPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPY-- 127 QQ QP P P Q QP PQQP P Q + P+ NL P + P+ Sbjct: 368 QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVS--LSNLIPGSPLPHVG 425 Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFP 163 V PH ++ + PV P + P PP P +FP Sbjct: 426 AALTVTTHPHISIKSE-PVSPSRERSPAPPPPAVFP 460 >gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] Length = 1488 Score = 52.8 bits (125), Expect = 2e-07 Identities = 58/189 (30%), Positives = 64/189 (33%), Gaps = 44/189 (23%) Query: 19 LPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLH-HQIIPVLSQQHPPTH 77 LPP P P PL SI PP S P+G H H PV QH + Sbjct: 1290 LPPPPQQP----------PPLPQLGSIPPPPASA--PPVGPHRHFHAHGPVPGPQH---Y 1334 Query: 78 TL-----------------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP---IQHHQP 117 TL PH P+ P+ P P H P I H P Sbjct: 1335 TLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHP 1394 Query: 118 NLPPPAQQPYQPQPVQP-----QPHQPMQPQPPVHPMQPLPPQPPLP---PMFPMQPLPP 169 + P A P P PH P P P P+ P P PPLP P P PLPP Sbjct: 1395 QMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPP 1454 Query: 170 MLPDLTLEA 178 P L A Sbjct: 1455 TSPHGPLHA 1463 Score = 47.4 bits (111), Expect = 8e-06 Identities = 45/154 (29%), Positives = 54/154 (35%), Gaps = 30/154 (19%) Query: 47 PPYPSYGYEPMGGWLHHQIIPVL----SQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMP 102 P + +G P LH P+ + QHPP H P H I Q MMP Sbjct: 1351 PQFAPHGRHP----LHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQ--------MMP 1398 Query: 103 VPGQHSMTPIQHHQPNLPPPA---QQPYQPQPVQPQPHQPMQPQP---PVHPMQPLPPQP 156 G P PP P+ PQ PH P+ P P P+ P P P Sbjct: 1399 AAGAAG-------GPGSRPPGGSYSHPHHPQSPL-SPHSPIPPHPSYPPLPPPSPHTPHS 1450 Query: 157 PLPPMFPMQPLPPMLPDLTLEAWPSTDKTKREEV 190 PLPP P PL P T + K K + Sbjct: 1451 PLPPTSPHGPLHASGPPGTANPPSANPKAKPSRI 1484 Score = 38.1 bits (87), Expect = 0.005 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 9/89 (10%) Query: 76 THTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQ 135 TH HHH V+P GQ + + P PA PY P P QP Sbjct: 1238 THHHHHHHHHGHSHGGLGVLPD-------GQSKLQALHAQYCQGPGPAPPPYLP-PQQPS 1289 Query: 136 PHQPMQPQPPVHPMQPLPPQP-PLPPMFP 163 P Q PP+ + +PP P PP+ P Sbjct: 1290 LPPPPQQPPPLPQLGSIPPPPASAPPVGP 1318 Score = 27.7 bits (60), Expect = 6.3 Identities = 11/25 (44%), Positives = 14/25 (56%) Query: 134 PQPHQPMQPQPPVHPMQPLPPQPPL 158 P+PHQ M P PP P + Q P+ Sbjct: 1174 PRPHQRMPPPPPPPPPEEYKSQRPV 1198 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 52.4 bits (124), Expect = 2e-07 Identities = 36/113 (31%), Positives = 44/113 (38%), Gaps = 15/113 (13%) Query: 67 PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126 P+ S P + P V A + P P+ P PG + P PPP P Sbjct: 650 PITSADCPKPMVVTPG--AAAVAAPSVLAPTLPLPPPPGFPPLPP--------PPPPPPP 699 Query: 127 YQPQPVQPQPHQPMQPQPPVHPM-----QPLPPQPPLPPMFPMQPLPPMLPDL 174 P+ P P P PP HP PLP P +PP + PLPP P L Sbjct: 700 QPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGL 752 Score = 52.0 bits (123), Expect = 3e-07 Identities = 34/91 (37%), Positives = 40/91 (43%), Gaps = 13/91 (14%) Query: 75 PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134 PT L P P +P P P QP P+P P+ P PPP P P P Sbjct: 677 PTLPLPPPPGFPPLPPPPPPPPPQPGFPMP-----PPLPPPPP--PPPPAHPAVTVPPPP 729 Query: 135 QPHQPMQPQPPVHPMQPLPPQPPLPP-MFPM 164 P P P PP+ LPP PP PP +FP+ Sbjct: 730 LPAPPGVPPPPI-----LPPLPPFPPGLFPV 755 Score = 43.1 bits (100), Expect = 1e-04 Identities = 33/97 (34%), Positives = 40/97 (41%), Gaps = 19/97 (19%) Query: 86 PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP--PPAQQPYQPQPVQPQPHQPMQPQ 143 P+ A P +PM+ PG ++ P LP PP P P P P P QP P Sbjct: 650 PITSADCP----KPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM 705 Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180 PP P PP PP P PP P +T+ P Sbjct: 706 PP--------PLPPPPP-----PPPPAHPAVTVPPPP 729 Score = 39.7 bits (91), Expect = 0.002 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 17/99 (17%) Query: 89 PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQ--PHQPMQPQPPV 146 PA P++P + G ++P PPA++ P+ P+ P ++ +P Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSP--------EPPAKEVEARPPLSPERAPEHDLEVEPEP 1270 Query: 147 HPMQPLPPQPPLPP----MFPMQPLPPMLPDLTLEAWPS 181 M PLP QPPLPP P PP P+ T + PS Sbjct: 1271 PMMLPLPLQPPLPPPRPPR---PPSPPPEPETTDASHPS 1306 Score = 39.3 bits (90), Expect = 0.002 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 4/83 (4%) Query: 96 PQQPMMPVPGQHSMTPIQHHQPNLP----PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQP 151 P+ P V + ++P + + +L PP P QP P P P P PP P Sbjct: 1241 PEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETT 1300 Query: 152 LPPQPPLPPMFPMQPLPPMLPDL 174 P +PP + PP P L Sbjct: 1301 DASHPSVPPEPLAEDHPPHTPGL 1323 Score = 37.4 bits (85), Expect = 0.008 Identities = 36/122 (29%), Positives = 45/122 (36%), Gaps = 28/122 (22%) Query: 86 PVVPAQQPVIPQQPMMPVPGQHSMTP---IQHHQPNLPPPAQQ---------PYQPQ-PV 132 P++PA P PM PG+ +P + P + PPA P QPQ PV Sbjct: 1459 PLLPAPLASCPP-PMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPV 1517 Query: 133 QPQPHQPMQ------------PQPPVHPMQPLPPQPPL--PPMFPMQPLPPMLPDLTLEA 178 P H P P PP+ P P PP PP P P + L P + Sbjct: 1518 FPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577 Query: 179 WP 180 P Sbjct: 1578 GP 1579 Score = 32.7 bits (73), Expect = 0.20 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Query: 96 PQQPMMPVPG-QHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQ--PQPPVHPMQPL 152 P P PG + + +P Q + PPP ++P + + P PP PL Sbjct: 383 PPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPP-----PL 437 Query: 153 PPQPPLPPMFPMQPLPPMLPD 173 PP PL P P P PD Sbjct: 438 PPAEPLAKEKPGTPPGPPPPD 458 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.140 0.487 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,746,505 Number of Sequences: 37866 Number of extensions: 974642 Number of successful extensions: 29027 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 875 Number of HSP's successfully gapped in prelim test: 968 Number of HSP's that attempted gapping in prelim test: 7683 Number of HSP's gapped (non-prelim): 9617 length of query: 191 length of database: 18,247,518 effective HSP length: 96 effective length of query: 95 effective length of database: 14,612,382 effective search space: 1388176290 effective search space used: 1388176290 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.