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Search of human proteins with 4501879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4501879 acrosomal vesicle protein 1 isoform a precursor
[Homo sapiens]
(265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo... 546 e-156
gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo... 498 e-141
gi|9955929 acrosomal vesicle protein 1 isoform c precursor [Homo... 388 e-108
gi|9955931 acrosomal vesicle protein 1 isoform d precursor [Homo... 337 5e-93
gi|9955937 acrosomal vesicle protein 1 isoform f precursor [Homo... 280 7e-76
gi|9955933 acrosomal vesicle protein 1 isoform e precursor [Homo... 279 2e-75
gi|9955941 acrosomal vesicle protein 1 isoform h precursor [Homo... 231 5e-61
gi|9955935 acrosomal vesicle protein 1 isoform j precursor [Homo... 181 6e-46
gi|9955945 acrosomal vesicle protein 1 isoform k precursor [Homo... 94 1e-19
gi|38261962 activating transcription factor 7 interacting protei... 61 1e-09
gi|222136622 prostate and testis expressed 3 [Homo sapiens] 55 8e-08
gi|221554530 prostate and testis expressed 4 [Homo sapiens] 50 2e-06
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 50 2e-06
gi|57864582 hornerin [Homo sapiens] 48 1e-05
gi|62122917 filaggrin family member 2 [Homo sapiens] 47 2e-05
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 47 2e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 46 3e-05
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 43 2e-04
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 43 2e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 42 4e-04
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|60097902 filaggrin [Homo sapiens] 42 7e-04
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 41 0.001
gi|49087132 sal-like 2 [Homo sapiens] 41 0.001
gi|150170670 piccolo isoform 2 [Homo sapiens] 41 0.001
gi|150378539 piccolo isoform 1 [Homo sapiens] 41 0.001
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 40 0.002
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 40 0.002
>gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo
sapiens]
Length = 265
Score = 546 bits (1406), Expect = e-156
Identities = 265/265 (100%), Positives = 265/265 (100%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS
Sbjct: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS
Sbjct: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
Query: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
Query: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
>gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo
sapiens]
Length = 246
Score = 498 bits (1282), Expect = e-141
Identities = 246/265 (92%), Positives = 246/265 (92%), Gaps = 19/265 (7%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS
Sbjct: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS
Sbjct: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS--------------- 165
Query: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 166 ----GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 221
Query: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 222 SMNLFSHGTRMQIICCRNQSFCNKI 246
>gi|9955929 acrosomal vesicle protein 1 isoform c precursor [Homo
sapiens]
Length = 210
Score = 388 bits (996), Expect = e-108
Identities = 201/265 (75%), Positives = 204/265 (76%), Gaps = 55/265 (20%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELS--------------------------------- 27
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
GS +H +S + GEPAATEHAEGEHTVGEQPSGEQPS
Sbjct: 28 --------GSIDHQTSV--------------QQLPGEPAATEHAEGEHTVGEQPSGEQPS 65
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS
Sbjct: 66 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 125
Query: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 126 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 185
Query: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 186 SMNLFSHGTRMQIICCRNQSFCNKI 210
>gi|9955931 acrosomal vesicle protein 1 isoform d precursor [Homo
sapiens]
Length = 195
Score = 337 bits (865), Expect = 5e-93
Identities = 183/265 (69%), Positives = 186/265 (70%), Gaps = 70/265 (26%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GEQPSGEQPS
Sbjct: 22 QPNELS--GSIDHQTSVQQLP-----------------------------GEQPSGEQPS 50
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS
Sbjct: 51 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 110
Query: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 111 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 170
Query: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 171 SMNLFSHGTRMQIICCRNQSFCNKI 195
>gi|9955937 acrosomal vesicle protein 1 isoform f precursor [Homo
sapiens]
Length = 170
Score = 280 bits (717), Expect = 7e-76
Identities = 136/153 (88%), Positives = 139/153 (90%), Gaps = 4/153 (2%)
Query: 113 QPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE 172
QP+ S +H + Q L GEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE
Sbjct: 22 QPNELSGSIDHQTSVQQLP----GEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE 77
Query: 173 QASGAPISSTSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMV 232
QASGAPISSTSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMV
Sbjct: 78 QASGAPISSTSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMV 137
Query: 233 QGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 265
QGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 138 QGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 170
Score = 111 bits (278), Expect = 6e-25
Identities = 63/101 (62%), Positives = 66/101 (65%), Gaps = 15/101 (14%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGE S E PS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEQPSDEQPS---------- 50
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAAT 101
EHGS E S + E SGEHA E ASG P ++
Sbjct: 51 -----GEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISS 86
>gi|9955933 acrosomal vesicle protein 1 isoform e precursor [Homo
sapiens]
Length = 176
Score = 279 bits (714), Expect = 2e-75
Identities = 161/265 (60%), Positives = 164/265 (61%), Gaps = 89/265 (33%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GE GEQPSG
Sbjct: 22 QPNELS--GSIDHQTS------------------------VQQLPGEQPSGEQPSG---- 51
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS
Sbjct: 52 -EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS--------------- 95
Query: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 96 ----GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 151
Query: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 152 SMNLFSHGTRMQIICCRNQSFCNKI 176
>gi|9955941 acrosomal vesicle protein 1 isoform h precursor [Homo
sapiens]
Length = 155
Score = 231 bits (589), Expect = 5e-61
Identities = 143/265 (53%), Positives = 146/265 (55%), Gaps = 110/265 (41%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GEQPSGEQPS
Sbjct: 22 QPNELS--GSIDHQTSVQQLP-----------------------------GEQPSGEQPS 50
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS
Sbjct: 51 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 110
Query: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
STST GGKLQFMVQGCENMCP
Sbjct: 111 STST----------------------------------------GGKLQFMVQGCENMCP 130
Query: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 131 SMNLFSHGTRMQIICCRNQSFCNKI 155
>gi|9955935 acrosomal vesicle protein 1 isoform j precursor [Homo
sapiens]
Length = 121
Score = 181 bits (459), Expect = 6e-46
Identities = 86/104 (82%), Positives = 89/104 (85%), Gaps = 4/104 (3%)
Query: 166 GEHASGEQASGAPISSTST----GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKK 221
G + + SG+ TS GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKK
Sbjct: 18 GTSSQPNELSGSIDHQTSVQQLPGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKK 77
Query: 222 IFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 265
IFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 78 IFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 121
Score = 83.2 bits (204), Expect = 2e-16
Identities = 41/41 (100%), Positives = 41/41 (100%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
>gi|9955945 acrosomal vesicle protein 1 isoform k precursor [Homo
sapiens]
Length = 81
Score = 94.0 bits (232), Expect = 1e-19
Identities = 41/41 (100%), Positives = 41/41 (100%)
Query: 225 GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 265
GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 41 GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 81
Score = 83.2 bits (204), Expect = 2e-16
Identities = 41/41 (100%), Positives = 41/41 (100%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 60.8 bits (146), Expect = 1e-09
Identities = 34/97 (35%), Positives = 53/97 (54%)
Query: 85 SGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQP 144
SG+ + S EP++++ A G+ T G+ PSG+ G+ SG+ +L SG+ S +
Sbjct: 151 SGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDATADDLSSGDPTSSDPI 210
Query: 145 SGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISS 181
GE E SG+ A+ + S E S + ASGAP S+
Sbjct: 211 PGEPVPVEPISGDCAADDIASSEITSVDLASGAPAST 247
Score = 58.2 bits (139), Expect = 7e-09
Identities = 43/145 (29%), Positives = 69/145 (47%)
Query: 40 PGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPA 99
PG+ + + S A +++SG T SE SS+ S T + SG+ + + SG+
Sbjct: 136 PGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDAT 195
Query: 100 ATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQA 159
A + + G+ T + GE E +SG+ ++ S E S + SG S + S + A
Sbjct: 196 ADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLA 255
Query: 160 SGEQPSGEHASGEQASGAPISSTST 184
SG+ S E AS + A+G S T
Sbjct: 256 SGDLSSSELASDDLATGELASDELT 280
Score = 53.5 bits (127), Expect = 2e-07
Identities = 28/89 (31%), Positives = 45/89 (50%)
Query: 91 SEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGS 150
+E SG+PA + G+ G SG+ SG+ S E S+ SG+ S + PSG+
Sbjct: 127 AEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSP 186
Query: 151 GEQPSGEQASGEQPSGEHASGEQASGAPI 179
G+ SG+ + + SG+ S + G P+
Sbjct: 187 GDATSGDATADDLSSGDPTSSDPIPGEPV 215
Score = 52.4 bits (124), Expect = 4e-07
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Query: 65 LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHL 124
LS H + SK AE SG+ A + +G+PA+ A G+ T G+ S E S +
Sbjct: 112 LSPHNITPEPVSK-LPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAA 170
Query: 125 SGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
SG + SG+ PS + G+ SG+ + + +SG+ S + GE PIS
Sbjct: 171 SG-----DATSGDAPSGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPIS 221
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG 156
EP + + A G+ G+ SG SG+ SG+ S E S + SG+ SG+ PSG
Sbjct: 128 EPVSGDPAPGDLDAGDPASGVLASGDSTSGDPT-----SSEPSSSDAASGDATSGDAPSG 182
Query: 157 EQASGEQPSGEHASGEQASGAPISS 181
+ + G+ SG+ + + +SG P SS
Sbjct: 183 DVSPGDATSGDATADDLSSGDPTSS 207
Score = 39.3 bits (90), Expect = 0.004
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 108 HTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQ-----ASGE 162
H + +P + P+ E +SG+ +L++G+ S SG+ SG+ S E ASG+
Sbjct: 115 HNITPEPVSKLPA-EPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGD 173
Query: 163 QPSGEHASGEQASGAPISSTSTGTILN 189
SG+ SG+ + G S +T L+
Sbjct: 174 ATSGDAPSGDVSPGDATSGDATADDLS 200
>gi|222136622 prostate and testis expressed 3 [Homo sapiens]
Length = 98
Score = 54.7 bits (130), Expect = 8e-08
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 186 TILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLF 245
T L C TC +C RG G C Q + CML +I++ LQ C+ C M F
Sbjct: 19 TSLQCITCHLRTRTDRCRRGFGVCTAQKGEACMLLRIYQRNTLQISYMVCQKFCRDMT-F 77
Query: 246 SHGTRMQIICCRNQSFCN 263
R + C N ++CN
Sbjct: 78 DLRNRTYVHTCCNYNYCN 95
>gi|221554530 prostate and testis expressed 4 [Homo sapiens]
Length = 98
Score = 50.4 bits (119), Expect = 2e-06
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 188 LNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSH 247
L C TC Y + KC+ G GTCI + ++ C F G K + C+ C
Sbjct: 23 LKCNTCIY-TEGWKCMAGRGTCIAKENELCSTTAYFRGDKHMYSTHMCKYKCREEESSKR 81
Query: 248 GTRMQIICCRNQSFCN 263
G +CC +++FCN
Sbjct: 82 GLLRVTLCC-DRNFCN 96
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 50.1 bits (118), Expect = 2e-06
Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 7/142 (4%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSE-HGSS 76
G P+E S H + Q P + S A + T+ + SS+ H
Sbjct: 296 GPPPPPDERDHS--HGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK 353
Query: 77 KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESG 136
H+ +H G H + H +H G H G P G P G H G P
Sbjct: 354 HHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQD 413
Query: 137 EQPSDEQPSGE----HGSGEQP 154
P D P + HG G P
Sbjct: 414 YGPCDPPPHNQGHCCHGHGPPP 435
Score = 36.2 bits (82), Expect = 0.030
Identities = 19/81 (23%), Positives = 26/81 (32%), Gaps = 5/81 (6%)
Query: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ 143
T G + H+ ++ H H+ + P G P H P + P
Sbjct: 331 TFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH-----PHEHDTHRQHPHGHH 385
Query: 144 PSGEHGSGEQPSGEQASGEQP 164
P G H G P G G P
Sbjct: 386 PHGHHPHGHHPHGHHPHGHHP 406
Score = 35.8 bits (81), Expect = 0.040
Identities = 19/78 (24%), Positives = 27/78 (34%), Gaps = 1/78 (1%)
Query: 92 EHAS-GEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGS 150
+HA+ G A H+ ++ P +H G P + + P G H
Sbjct: 328 QHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPH 387
Query: 151 GEQPSGEQASGEQPSGEH 168
G P G G P G H
Sbjct: 388 GHHPHGHHPHGHHPHGHH 405
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 47.8 bits (112), Expect = 1e-05
Identities = 51/183 (27%), Positives = 79/183 (43%), Gaps = 22/183 (12%)
Query: 21 SQPNELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLS-EHGSSEHGSSK 77
S + SG H++ Q G + S S ++ + ++SG + S +HGSS SS
Sbjct: 340 SGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSS 399
Query: 78 H----TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQ---------PSGEHL 124
+ + + H+SG +H+SG + H + G+ PS Q SG ++
Sbjct: 400 YGQHESASRHSSGR---GQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYV 456
Query: 125 SGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQPSGEHASGEQASGAPISST 182
SG S E S E SG +HGSG S SG+ + GE+ + SS+
Sbjct: 457 SGSGYSSGFGHHES-SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSS 515
Query: 183 STG 185
S G
Sbjct: 516 SYG 518
Score = 45.4 bits (106), Expect = 5e-05
Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 19/180 (10%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLS-EHGSSEHGSSKHT 79
S + SG H++ Q + S ++ + ++SG ++ S +H SS SS +
Sbjct: 809 SGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSY- 867
Query: 80 VAEHTSGEHAES---EHASGEPAATEHAEGEHTVGEQPS---------GEQPSGEHLSGE 127
+H S H S H SG + H + G+ PS SG H SG
Sbjct: 868 -GQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGS 926
Query: 128 QPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
S G + S Q SG +HGSG S SG+ + EQ + SS+S G
Sbjct: 927 GQSSGF--GHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG 984
Score = 45.4 bits (106), Expect = 5e-05
Identities = 50/171 (29%), Positives = 72/171 (42%), Gaps = 12/171 (7%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
RG+ S+ + G + G+ S S +E+SSG ++ S+HGS S
Sbjct: 1131 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
Query: 76 SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLSE 132
S + SG+ + E ++ H G+H G + S G Q SG SG P S
Sbjct: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSH-YGQHGSGSRQSSGHGRQGSG---SGHSP-SR 1245
Query: 133 LESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS--GEQASGAPISS 181
G G+HGSG S + E SG H+S G+ SG+ SS
Sbjct: 1246 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG-HSSVFGQHESGSGHSS 1295
Score = 44.7 bits (104), Expect = 9e-05
Identities = 53/172 (30%), Positives = 73/172 (42%), Gaps = 17/172 (9%)
Query: 16 ARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHG 74
+R + S SGS +S Q PG S +E+SSG ++ S+HGS
Sbjct: 2075 SRQSPSYGRHGSGSGRSSSSGQHGPGL-----GESSGFGHHESSSGQSSSYSQHGSGSGH 2129
Query: 75 SSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLS 131
SS + SG+ + E G + + G+H G + S G Q SG SG P S
Sbjct: 2130 SSGYGQHGSRSGQSSRGER-HGSSSGSSSRYGQHGSGSRQSSGHGRQGSG---SGHSP-S 2184
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS--GEQASGAPISS 181
G G+HGSG S + E SG H+S G+ SG+ SS
Sbjct: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG-HSSVFGQHESGSGHSS 2235
Score = 44.3 bits (103), Expect = 1e-04
Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 17/142 (11%)
Query: 58 TSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHA-----SGE-PAATEHAEGE---H 108
TS +T + GSS SS H +H SG S + SG+ P+ H G
Sbjct: 1786 TSGQSSTFDQEGSSTGQSSSH--GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 1843
Query: 109 TVGEQPSGE---QPSGEHLSGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQ 163
+ G+ SG SG H SG S E S Q SG +HGSG S
Sbjct: 1844 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQSSGYTQHGSGSGHSSSYEQHGS 1902
Query: 164 PSGEHASGEQASGAPISSTSTG 185
SG+ + GEQ + SS+S G
Sbjct: 1903 RSGQSSRGEQHGSSSGSSSSYG 1924
Score = 43.9 bits (102), Expect = 1e-04
Identities = 49/171 (28%), Positives = 72/171 (42%), Gaps = 12/171 (7%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
RG+ S+ + G + G+ S S +E+SSG ++ S+HGS S
Sbjct: 2541 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2600
Query: 76 SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLSE 132
S + SG+ + E ++ H G+H G + S G Q SG SG+ P S
Sbjct: 2601 SGYGQHGSRSGQSSRGERHGSSSGSSSH-YGQHGSGSRQSSGHGRQGSG---SGQSP-SR 2655
Query: 133 LESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS--GEQASGAPISS 181
G G+HGSG S + E G H+S G+ SG+ SS
Sbjct: 2656 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLG-HSSVFGQHESGSGHSS 2705
Score = 43.5 bits (101), Expect = 2e-04
Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 23/179 (12%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSS------ 71
G+SS + G TS G + S + +E+ SG S+HGS+
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG-YSQHGSASGHFSS 840
Query: 72 --EHGSSKHTVAEHTSGEHAESEHASG----EPAATEHAEGEHTVGEQPSGEQPS-GEHL 124
HGS+ + +SG+H S S +A+ HA G G SG+ P G+
Sbjct: 841 QGRHGST--SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHG-SGSGQSPGHGQRG 897
Query: 125 SGE-QPLSELESGEQPSDEQPSGEHGSGEQPS---GEQASGEQPSG--EHASGEQASGA 177
SG Q S G SG HGSG S G ++S Q SG +H SG S +
Sbjct: 898 SGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
Score = 43.1 bits (100), Expect = 2e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 10/127 (7%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
+++ SG ++ S+HGS SS + SG+ + SE G + + G+H G
Sbjct: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ-HGSSSGLSSSYGQHGSGSHQ 761
Query: 115 S---GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS- 170
S G Q SG SG P S + G G+HGSG S E SG+ +
Sbjct: 762 SSGHGRQGSG---SGHSP-SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGF 817
Query: 171 GEQASGA 177
G+ SG+
Sbjct: 818 GQHESGS 824
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/171 (28%), Positives = 74/171 (43%), Gaps = 16/171 (9%)
Query: 18 GTSSQPNE-LSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
G+ PN GS Q+S G S S + +++SSG ++ S+HGS S
Sbjct: 198 GSGQSPNYGQHGSGSGQSSSNDTHG---SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS 254
Query: 76 SKHTVAEHTSGEHAESE-HASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLS 131
S + SG+ + E H S +++ + G+H G + S G Q SG Q S
Sbjct: 255 SGYGQHGSRSGQSSRGERHRSSSGSSSSY--GQHGSGSRQSLGHGRQGSGSR----QSPS 308
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS-GEQASGAPISS 181
+ G G+HGSG S + E SG+ + G+ SG+ SS
Sbjct: 309 HVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSS 359
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 19/180 (10%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGSS 76
G+ S + G +S G + S + +E+ SG ++ S+HGS SS
Sbjct: 313 GSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSS 372
Query: 77 KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE-QPLSELES 135
TSG+ A S G + + G+H + S + G+H SG Q +
Sbjct: 373 SQGQHGSTSGQ-ASSSGQHGSSSRQSSSYGQHESASRHSSGR--GQHSSGSGQSPGHGQR 429
Query: 136 GEQPSDEQPSGEHGSG---EQPSGEQASG---------EQPSGEHASG--EQASGAPISS 181
G SG+HG+G SG SG + S EH+SG + SG+ SS
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
Score = 42.7 bits (99), Expect = 3e-04
Identities = 45/142 (31%), Positives = 59/142 (41%), Gaps = 17/142 (11%)
Query: 58 TSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHA-----SGE-PAATEHAEGE---H 108
TS +T + GSS SS H +H SG S + SG+ P+ H G
Sbjct: 2256 TSGQSSTFDQEGSSTGQSSSH--GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 2313
Query: 109 TVGEQPSGE---QPSGEHLSGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQ 163
+ G+ SG SG H SG S E S Q SG +HGSG S
Sbjct: 2314 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQSSGYTQHGSGSGHSSSYEQHGS 2372
Query: 164 PSGEHASGEQASGAPISSTSTG 185
SG+ + GE+ + SS+S G
Sbjct: 2373 RSGQSSRGERHGSSSGSSSSYG 2394
Score = 42.0 bits (97), Expect = 6e-04
Identities = 44/169 (26%), Positives = 63/169 (37%), Gaps = 7/169 (4%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNT-LSEHGSS 71
S G S + SG H + G + S S + +SSGL++ +HGS
Sbjct: 699 SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSG 758
Query: 72 EHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQ 128
H SS H SG H+ S G + + G+H G S G SG +
Sbjct: 759 SHQSSGHGRQGSGSG-HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGF 817
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGA 177
E SG+ S + H S + G + SG+H S S +
Sbjct: 818 GQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSS 866
Score = 42.0 bits (97), Expect = 6e-04
Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 16/174 (9%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG-LNTLSEHGSSE 72
GS G SS H + + G S S + +SSG +T +HGS+
Sbjct: 1498 GSGSGWSSSRGPYESGSSHSSGL----GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 1553
Query: 73 HGSS---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS-GEQPSGEHLSGEQ 128
SS +H + S H + H SG ++ + G+ P G++ SG S
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQ--HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1611
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS-GEQASGAPISS 181
SG S SG+HGSG S E SG+ +S + SG+ SS
Sbjct: 1612 GRHGSGSGRSSS----SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 1661
Score = 42.0 bits (97), Expect = 6e-04
Identities = 51/191 (26%), Positives = 74/191 (38%), Gaps = 29/191 (15%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
G G+SS+ + G H + +Q G + + SGL S HG
Sbjct: 1676 GERHGSSSRSSSRYGQ--HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS 1733
Query: 74 GSSKHTVA---EHTSGEHA---ESEHASGEPAA-TEHAEGEHTVGEQPSGEQPSGEHLSG 126
GS + + E SG + + E SG +A ++H G Q SG+ +
Sbjct: 1734 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1793
Query: 127 EQPLSELESGEQPSDEQPSGEHGSGEQPS---GEQASG--EQPS-GEHASG--------E 172
+Q G G+HGSG S G+Q SG + PS G H SG +
Sbjct: 1794 DQ------EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 1847
Query: 173 QASGAPISSTS 183
SG+ SS+S
Sbjct: 1848 HGSGSGWSSSS 1858
Score = 41.6 bits (96), Expect = 7e-04
Identities = 55/197 (27%), Positives = 75/197 (38%), Gaps = 34/197 (17%)
Query: 14 GSARGTSSQPNE-LSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-------- 64
GS G S P+ GS Q+S G + S S + YE+ SG ++
Sbjct: 1000 GSGSGQSPSPSRGRHGSGSGQSSSY---GPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056
Query: 65 ------LSEHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPS-- 115
+HGSS SS H TSG+ + +H + ++ H G+H G S
Sbjct: 1057 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH--GQHGSGSSQSSG 1114
Query: 116 -GEQPSGEHLS---------GEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G Q SG S Q S G SG+HGSG S E S
Sbjct: 1115 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 1174
Query: 166 GEHAS-GEQASGAPISS 181
G+ +S + SG+ SS
Sbjct: 1175 GQSSSYSQHGSGSGHSS 1191
Score = 41.6 bits (96), Expect = 7e-04
Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 16/174 (9%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG-LNTLSEHGSSE 72
GS G SS H + + G S S + +SSG +T +HGS+
Sbjct: 2438 GSGSGWSSSRGPYESGSGHSSGL----GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 2493
Query: 73 HGSS---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS-GEQPSGEHLSGEQ 128
SS +H + S H + H SG ++ + G+ P G++ SG S
Sbjct: 2494 GQSSSCGQHGASSGQSSSHGQ--HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 2551
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS-GEQASGAPISS 181
SG S SG+HGSG S E SG+ +S + SG+ SS
Sbjct: 2552 GRHGSGSGRSSS----SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 2601
Score = 40.4 bits (93), Expect = 0.002
Identities = 51/192 (26%), Positives = 72/192 (37%), Gaps = 21/192 (10%)
Query: 14 GSARGTSSQPN-----ELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLS 66
GS R +SS + E SG H++S Q + S S + + SG ++
Sbjct: 1147 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHA-SGEPAATEHAEGEHTVG---EQPSGEQPSGE 122
E S GSS H +H SG S H G + + G H G G+ SG
Sbjct: 1207 ERHGSSSGSSSH-YGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS 1265
Query: 123 HLSGEQPLSELESGEQP---SDEQPSG------EHGSGEQPSGEQASGEQPSGEHASGEQ 173
S + E SG E SG +HGSG Q SG+ ++ +Q
Sbjct: 1266 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 1325
Query: 174 ASGAPISSTSTG 185
+ S+S G
Sbjct: 1326 EGSSTGQSSSYG 1337
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 23/190 (12%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLP---GEFFSLENPSDAEALYETSSGLNT-LSEHGS 70
S+RG + S + H+ S G+ S S + ++SG ++ +HG+
Sbjct: 1505 SSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564
Query: 71 SEHGSSKHTVAEHTSGEHAESEHA---SGEPAATEHAE-----------GEHTVGEQPSG 116
S SS H +H SG S + SG + H + G H G S
Sbjct: 1565 SSGQSSSH--GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 1622
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPS-GEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
SG+H SG S E S + S +HGSG S SG+ + GE+
Sbjct: 1623 S--SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1680
Query: 176 GAPISSTSTG 185
+ SS+ G
Sbjct: 1681 SSSRSSSRYG 1690
Score = 40.4 bits (93), Expect = 0.002
Identities = 52/193 (26%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 14 GSARGTSSQPN-----ELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLS 66
GS R +SS + E SG H++S Q + S S + + SG ++
Sbjct: 1617 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1676
Query: 67 E-HGSSEHGSSKHTVAEHTSGEHAESEHA-SGEPAATEHAEGEHTVG---EQPSGEQPSG 121
E HGSS SS++ +H SG S H G + + G H G G+ SG
Sbjct: 1677 ERHGSSSRSSSRY--GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 1734
Query: 122 EHLSGEQPLSELESGEQP---SDEQPSG------EHGSGEQPSGEQASGEQPSGEHASGE 172
S + E SG E SG +HGSG Q SG+ ++ +
Sbjct: 1735 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1794
Query: 173 QASGAPISSTSTG 185
Q + S+S G
Sbjct: 1795 QEGSSTGQSSSHG 1807
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/174 (25%), Positives = 69/174 (39%), Gaps = 11/174 (6%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEH 73
S+ G SS ++ H + G+ S S + +SSG ++ +HGS
Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGY----GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR 2167
Query: 74 GSSKHTVAEHTSGEH-AESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPL-S 131
SS H SG + H SG ++ H G+H G S + E SG +
Sbjct: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH--GQHGSGSGRSSSRGPYESRSGHSSVFG 2225
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
+ ESG S +HGSG Q SG+ ++ +Q + S+S G
Sbjct: 2226 QHESGSGHSSAY--SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 2277
Score = 39.3 bits (90), Expect = 0.004
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 23/190 (12%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLP---GEFFSLENPSDAEALYETSSGLNT-LSEHGS 70
S+RG + S + H+ S G+ S S + ++SG ++ +HG+
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1094
Query: 71 SEHGSSKHTVAEHTSGEHAESEHA---SGEPAATEHAE-----------GEHTVGEQPSG 116
S SS H +H SG S + SG + H + G H G S
Sbjct: 1095 SSGQSSSH--GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 1152
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPS-GEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
SG+H SG S E S + S +HGSG S SG+ + GE+
Sbjct: 1153 S--SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1210
Query: 176 GAPISSTSTG 185
+ SS+ G
Sbjct: 1211 SSSGSSSHYG 1220
Score = 39.3 bits (90), Expect = 0.004
Identities = 46/150 (30%), Positives = 67/150 (44%), Gaps = 16/150 (10%)
Query: 41 GEFFSLENPSDAEALYETSSGLNTLS-EHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEP 98
G+ S S + + + SG ++ S +HGS SS E +SG+ + S+H SG
Sbjct: 1599 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG-- 1656
Query: 99 AATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEH-----GSGEQ 153
+ H+ G G + SG+ GE G S G+ S + S H GSG+
Sbjct: 1657 --SGHSSGYGQHGSR-SGQSSRGER-HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQS 1712
Query: 154 PS-GEQASGEQPSGEHASGEQASGAPISST 182
PS G SG S H G+ SG+ SS+
Sbjct: 1713 PSRGRHGSGLGHSSSH--GQHGSGSGRSSS 1740
Score = 39.3 bits (90), Expect = 0.004
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 23/190 (12%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLP---GEFFSLENPSDAEALYETSSGLNT-LSEHGS 70
S+RG + S + H+ S G+ S S + ++SG ++ +HG+
Sbjct: 2445 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 2504
Query: 71 SEHGSSKHTVAEHTSGEHAESEHA---SGEPAATEHAE-----------GEHTVGEQPSG 116
S SS H +H SG S + SG + H + G H G S
Sbjct: 2505 SSGQSSSH--GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 2562
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPS-GEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
SG+H SG S E S + S +HGSG S SG+ + GE+
Sbjct: 2563 S--SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2620
Query: 176 GAPISSTSTG 185
+ SS+ G
Sbjct: 2621 SSSGSSSHYG 2630
Score = 38.1 bits (87), Expect = 0.008
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 27/186 (14%)
Query: 14 GSARGTSSQPNEL-SGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG-LNTLSEHGSS 71
GS+ G SS + SGS + QQ G S + + + SG ++ +HGS
Sbjct: 2267 GSSTGQSSSHGQHGSGSSQSSSYGQQGSGS-----GQSPSRGRHGSGSGHSSSYGQHGSG 2321
Query: 72 EHGSSKHTVAEHTSGEHAESEHASGEPAA------TEHAEGE-HTVGEQPSGEQPSGEHL 124
SS H SG S E ++ T+H G H+ + G + SG+
Sbjct: 2322 SGWSSSS--GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSR-SGQSS 2378
Query: 125 SGEQPLSELES----GEQPSDEQPS---GEHGSGEQPSGEQASGEQPSGEHASGEQASGA 177
GE+ S S G+ S + S G+HGSG S + G SG SG+ +S +
Sbjct: 2379 RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG---SGQSSSYS 2435
Query: 178 PISSTS 183
P S S
Sbjct: 2436 PYGSGS 2441
Score = 37.7 bits (86), Expect = 0.010
Identities = 51/196 (26%), Positives = 74/196 (37%), Gaps = 30/196 (15%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG-LNTLSEHGSSE 72
GS R +S P E SGS H + + G S S + +SSG +T +HGS+
Sbjct: 564 GSGRSSSRGPYE-SGS-GHSSGL----GHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 617
Query: 73 HGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPS--------------GE 117
SS TSG+ + +H SG ++ + + G+ PS G+
Sbjct: 618 GQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQ 677
Query: 118 QPSGEHLSGEQPLSELESGEQPSDEQPSG--------EHGSGEQPSGEQASGEQPSGEHA 169
SG S SG+ SG +HGSG S SG+ +
Sbjct: 678 HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSS 737
Query: 170 SGEQASGAPISSTSTG 185
EQ + S+S G
Sbjct: 738 RSEQHGSSSGLSSSYG 753
Score = 37.7 bits (86), Expect = 0.010
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 35/179 (19%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
GS G S + H +S G+ S S + YE+ SG +++ G E
Sbjct: 1236 GSGSGHSPSRGRHGSGLGHSSS----HGQHGSGSGRSSSRGPYESRSGHSSV--FGQHES 1289
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
GS H+S A S+H SG + T G+ + +Q E S Q S
Sbjct: 1290 GSG------HSS---AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ---EGSSTGQSSSYG 1337
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS-GEHASG--------EQASGAPISSTS 183
G S G HG+G SG+ PS G H SG + SG+ SS+S
Sbjct: 1338 HRGSGSSQSSGYGRHGAG--------SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 1388
Score = 37.7 bits (86), Expect = 0.010
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 13/140 (9%)
Query: 58 TSSGLNTLSEHGSSEHGSSKH----TVAEHTSGEHAESEHASGEPAATEHAEGE---HTV 110
TS +T + GSS SS + + + +SG + P+ H G +
Sbjct: 1316 TSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSY 1375
Query: 111 GEQPSGE---QPSGEHLSGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQPS 165
G+ SG SG H SG S E S Q SG +HGSG S S
Sbjct: 1376 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQSSGCTQHGSGSGHSSSYEQHGSRS 1434
Query: 166 GEHASGEQASGAPISSTSTG 185
G+ + GE+ + SS+S G
Sbjct: 1435 GQSSRGERHGSSSGSSSSYG 1454
Score = 37.7 bits (86), Expect = 0.010
Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 23/184 (12%)
Query: 14 GSARGTSSQ-------PNELSGSIDHQTSVQQLP--GEFFSLENPSDAEALYETSSGLNT 64
GS+ G SS ++ SG H Q P G S S + + + SG ++
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386
Query: 65 LS-EHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
S HGS SS E +S + + ++H SG ++ + + G+ GE+
Sbjct: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER---- 1442
Query: 123 HLSGEQPLSELESGEQPSDEQPS---GEHGSGEQPSGEQASGEQPSGEHASGEQASGAPI 179
G S G+ S + S G+HGSG S + G SG SG+ +S +P
Sbjct: 1443 --HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG---SGQSSSYSPY 1497
Query: 180 SSTS 183
S S
Sbjct: 1498 GSGS 1501
Score = 37.7 bits (86), Expect = 0.010
Identities = 41/129 (31%), Positives = 60/129 (46%), Gaps = 19/129 (14%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
+E+SS ++ ++HGS SS + SG+ + E G + + + G+H G +
Sbjct: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQ-HGSSSGSSSSYGQHGSGSRQ 1932
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQA 174
S G+H SG SG+ PS + G HGSG SG Q+S P G SG +
Sbjct: 1933 S--LGHGQHGSG--------SGQSPSPSR--GRHGSG---SG-QSSSYGPYGS-GSGWSS 1975
Query: 175 SGAPISSTS 183
S P S S
Sbjct: 1976 SRGPYESGS 1984
Score = 37.4 bits (85), Expect = 0.014
Identities = 53/194 (27%), Positives = 75/194 (38%), Gaps = 37/194 (19%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
GS+ G+SS + GS Q+ G S ++PS + +E SG S +G +
Sbjct: 508 GSSAGSSSSYGQ-HGSGSRQSLGHSRHGSG-SGQSPSPSRGRHE--SGSRQSSSYGPHGY 563
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAE---------GEHTVGEQPSGEQPSGEHL 124
GS + S E SG + H E G+H G G+H
Sbjct: 564 GSGR-------SSSRGPYESGSGHSSGLGHQESRSGQSSGYGQH--GSSSGHSSTHGQHG 614
Query: 125 SGEQPLSEL-ESGEQPSDEQPSGEHGSGEQPS---GEQ--ASGEQPS-GEHAS------- 170
S S + G G+HGSG S G+Q SG+ PS G H S
Sbjct: 615 STSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSS 674
Query: 171 -GEQASGAPISSTS 183
G+ SG+ SS++
Sbjct: 675 YGQHGSGSGWSSSN 688
Score = 37.4 bits (85), Expect = 0.014
Identities = 48/190 (25%), Positives = 72/190 (37%), Gaps = 23/190 (12%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLP---GEFFSLENPSDAEALYETSSGLNT-LSEHGS 70
S+RG + S + H+ S G+ S S + ++SG ++ +HG+
Sbjct: 1975 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGA 2034
Query: 71 SEHGSSKHTVAEHTSGEHAESEHA---SGEPAATEHAE-----------GEHTVGEQPSG 116
S SS H +H SG S + SG + H + G H G S
Sbjct: 2035 SSGQSSSH--GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 2092
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPS-GEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
SG+H G S E S + S +HGSG S SG+ + GE+
Sbjct: 2093 S--SGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2150
Query: 176 GAPISSTSTG 185
+ SS+ G
Sbjct: 2151 SSSGSSSRYG 2160
Score = 37.0 bits (84), Expect = 0.018
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 6/145 (4%)
Query: 41 GEFFSLENPSDAEALYETSSGLNTLS-EHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEP 98
G+ S S + + + SG ++ S +HG SS E +SG+ + S+H SG
Sbjct: 2069 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSG 2128
Query: 99 AATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPS-GE 157
++ + + G+ GE+ G + SG + S GSG PS G
Sbjct: 2129 HSSGYGQHGSRSGQSSRGER-HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
Query: 158 QASGEQPSGEHASGEQASGAPISST 182
SG S H G+ SG+ SS+
Sbjct: 2188 HGSGSGHSSSH--GQHGSGSGRSSS 2210
Score = 36.2 bits (82), Expect = 0.030
Identities = 47/187 (25%), Positives = 71/187 (37%), Gaps = 20/187 (10%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
GS G S + H +S G+ S S + YE+ G +++ G E
Sbjct: 2646 GSGSGQSPSRGRHGSGLGHSSS----HGQHGSGSGRSSSRGPYESRLGHSSV--FGQHES 2699
Query: 74 GSSKHTV-AEHTSGEH---AESEHASGE-PAATEHAEGEHT-----VGEQPSGEQPS--- 120
GS + ++H SG ++ +H S ++T EG T G + SG S
Sbjct: 2700 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 2759
Query: 121 GEHLSGE-QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPI 179
G H +G Q LS G G+HGSG S + SG+ G+
Sbjct: 2760 GRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNH 2819
Query: 180 SSTSTGT 186
S+G+
Sbjct: 2820 DGGSSGS 2826
Score = 35.4 bits (80), Expect = 0.052
Identities = 52/186 (27%), Positives = 72/186 (38%), Gaps = 30/186 (16%)
Query: 14 GSARGTSS----QPNELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLSE 67
GS R +SS + S H++S Q G + S S + + + SG ++ SE
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 68 -HGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
HGSS SS + +H SG + H G+H G S G H SG
Sbjct: 972 QHGSSSGSSSSY------------GQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSG 1017
Query: 127 EQPLSE---LESGEQPSDEQPSGEHGSGEQPS---GEQASGEQPS-GEH--ASGEQASGA 177
S SG S + E GSG E SG+ G+H +SG ++
Sbjct: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077
Query: 178 PISSTS 183
STS
Sbjct: 1078 QHGSTS 1083
Score = 34.3 bits (77), Expect = 0.12
Identities = 49/181 (27%), Positives = 67/181 (37%), Gaps = 26/181 (14%)
Query: 14 GSARGTSSQPN-------ELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNT 64
GS G SS + SG H++S Q G + S S + + + SG ++
Sbjct: 1379 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSS 1438
Query: 65 LSE-HGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH 123
E HGSS SS + +H SG + H G+H G S G H
Sbjct: 1439 RGERHGSSSGSSSSY------------GQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRH 1484
Query: 124 LSGE-QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS-GEQASGAPISS 181
SG Q S G G + SG S E SG+ + G+ S + SS
Sbjct: 1485 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1544
Query: 182 T 182
T
Sbjct: 1545 T 1545
Score = 33.5 bits (75), Expect = 0.20
Identities = 49/181 (27%), Positives = 67/181 (37%), Gaps = 26/181 (14%)
Query: 14 GSARGTSSQPN-------ELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNT 64
GS G SS + SG H++S Q G + S S + + + SG ++
Sbjct: 2319 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 2378
Query: 65 LSE-HGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH 123
E HGSS SS + +H SG + H G+H G S G H
Sbjct: 2379 RGERHGSSSGSSSSY------------GQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRH 2424
Query: 124 LSGE-QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS-GEQASGAPISS 181
SG Q S G G + SG S E SG+ + G+ S + SS
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484
Query: 182 T 182
T
Sbjct: 2485 T 2485
Score = 32.0 bits (71), Expect = 0.57
Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 10/123 (8%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHAS-GEPAATEHAEGEHTVGEQPSGEQPSGE-HL 124
+H S SS + E S H S G + G+H G SG+ S + H
Sbjct: 168 QHNSYSGQSSSY--GEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSG---SGQSSSNDTHG 222
Query: 125 SGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQPSGEHASGEQASGAPISST 182
SG S S + S Q SG +HGSG S SG+ + GE+ + SS+
Sbjct: 223 SGSGQSSGF-SQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSS 281
Query: 183 STG 185
S G
Sbjct: 282 SYG 284
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 47.0 bits (110), Expect = 2e-05
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 23/176 (13%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S ++ SG H ++ Q G F P + SSG G +H
Sbjct: 1081 SGSSQSSGYGQHGSNSGQTSG--FGQHRPGSGQ-----SSGFGQYGSGSGQSSGFGQHGS 1133
Query: 81 AEHTSGEHAESEHASGEPAATEHAEGEHT---VGEQPSGEQPS---GEHLSGEQPLSELE 134
S A+ E+ SG+ + +H G G+ SG P+ G+H+SG S
Sbjct: 1134 GTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFS--S 1191
Query: 135 SGEQPSDEQPS---GEHGSGEQPS-----GEQASGEQPSGEHASGEQASGAPISST 182
SG+ SD S G++GSG S GE E S H E G I++T
Sbjct: 1192 SGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTT 1247
Score = 45.1 bits (105), Expect = 7e-05
Identities = 46/177 (25%), Positives = 68/177 (38%), Gaps = 14/177 (7%)
Query: 21 SQPNELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKH 78
S + SG H + Q G + + S YE+ S ++ +HGS SS +
Sbjct: 1030 SSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGY 1089
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ 138
+H S S P + + + G G G+H SG S E
Sbjct: 1090 --GQHGSNSGQTSGFGQHRPGSGQ-SSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEY 1146
Query: 139 PSDEQPSGEHGSGEQPS---GEQASGEQPS---GEHASGE---QASGAPISSTSTGT 186
S + G+HG+G S G+ SG P+ G+H SG +SG IS + T
Sbjct: 1147 RSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQST 1203
Score = 43.9 bits (102), Expect = 1e-04
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 12/165 (7%)
Query: 20 SSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGSSKH 78
SS ++ SG H + G+ S + S Y + SG ++ +H S SS
Sbjct: 622 SSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGF 681
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH-LSGEQPLSELESGE 137
E SG + +H G ++ + + + G Q SG G+H LS Q S + G
Sbjct: 682 GQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSG-QTSG---FGQHELSSGQSSSFGQHGS 737
Query: 138 QPSDEQPSGEHGSGE-QPSG----EQASGEQPSGEHASG-EQASG 176
G+HGSG Q SG E SG+ G+H+SG Q+SG
Sbjct: 738 GSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSG 782
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/162 (26%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAE--------- 105
Y + SG ++ +HGS SS E SG+ + +H+SG ++ + +
Sbjct: 583 YGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 642
Query: 106 GEHTVGEQPS---GEQPSG--------EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQP 154
G+H G S G+ SG +H+SG S E S G+HG G
Sbjct: 643 GQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQ 702
Query: 155 SG------------------EQASGEQPS-GEHASGE-QASG 176
S E +SG+ S G+H SG Q+SG
Sbjct: 703 SSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSG 744
Score = 40.0 bits (92), Expect = 0.002
Identities = 47/176 (26%), Positives = 67/176 (38%), Gaps = 18/176 (10%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S + SG H+ S Q + + SG S G E S + +
Sbjct: 711 SSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770
Query: 81 AEHTSGEHAES---EHASGEPAAT-EHAEGEHT---VGEQPSGEQPS---GEHLSGEQPL 130
+H+SG S +H S + + +H G G+ SG S G+H SG
Sbjct: 771 GQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQS 830
Query: 131 SELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE-QASGAPISSTSTG 185
S E S + G+HGSG Q+SG G+H S Q SG +S+G
Sbjct: 831 SGFGQHESRSHQSSYGQHGSG----SSQSSG---YGQHGSSSGQTSGFGQHRSSSG 879
Score = 40.0 bits (92), Expect = 0.002
Identities = 49/197 (24%), Positives = 71/197 (36%), Gaps = 32/197 (16%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S + SG H++S Q G + + +G S G E S + +
Sbjct: 863 SSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSY 922
Query: 81 AEHTSGEHAESEHAS-GEPAATEHAEGEHT--------VGEQPSGEQPS---GEHLSGEQ 128
+H SG S + G + G+H G+ SG S G+H SG
Sbjct: 923 GQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSG 982
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPS---GEQAS--------GEQPS--------GEHA 169
S E S + G+HGSG S G+ S G+ S G+H
Sbjct: 983 KSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHG 1042
Query: 170 SG-EQASGAPISSTSTG 185
SG +Q+SG T +G
Sbjct: 1043 SGSDQSSGFGQHGTGSG 1059
Score = 38.5 bits (88), Expect = 0.006
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 7/160 (4%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEA----LYETSSGLNTLSEHGSSE 72
RG +++ QT + + FS + +D+E + S T S+ GS +
Sbjct: 1318 RGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGS-Q 1376
Query: 73 HGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSE 132
HG S+ TV E + ++ A+G + H + G + +G + SG S + +
Sbjct: 1377 HGESESTVHERHETTYGQTGEATGH-GHSGHGQSTQR-GSRTTGRRGSGHSESSDSEVHS 1434
Query: 133 LESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE 172
S S EQ G+ GS SG G + +G+
Sbjct: 1435 GGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGD 1474
Score = 37.7 bits (86), Expect = 0.010
Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 25/165 (15%)
Query: 41 GEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPA 99
G+ S S +E+ SG ++ +H S SS + +H S + + +H SG
Sbjct: 746 GQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY--GQHGSRQTSGFGQHGSGSSQ 803
Query: 100 ATEHAE-----------GEHTVGE-QPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGE 147
+T + G+H G Q SG G+H S S + G S G+
Sbjct: 804 STGFGQYGSGSGQSAGFGQHGSGSGQSSG---FGQHESRSHQSSYGQHGSGSSQSSGYGQ 860
Query: 148 HGSGE-QPSG----EQASGEQPS-GEHASGE-QASGAPISSTSTG 185
HGS Q SG +SG+ G+H SG Q+SG T +G
Sbjct: 861 HGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSG 905
Score = 36.2 bits (82), Expect = 0.030
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 15/118 (12%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS-GEH-L 124
+HGS SS E S + + +H SG ++ + G+ S E G+H L
Sbjct: 520 QHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGY-------GQYGSRETSGFGQHGL 572
Query: 125 SGEQPLSELESGEQPSDEQPSGEHGSGE-QPSG----EQASGEQPSGEHASG-EQASG 176
Q + G G+HGSG Q SG E SG+ G+H+SG Q+SG
Sbjct: 573 GSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSG 630
Score = 34.7 bits (78), Expect = 0.088
Identities = 33/134 (24%), Positives = 43/134 (32%), Gaps = 7/134 (5%)
Query: 59 SSGLNTLSEHGSSEHGSSKHTVAEHTSGE----HAESEHASGEPAATEHAEGEHTVGEQP 114
SSG + S+ S + HT G+ H ESE E T H + T G
Sbjct: 1800 SSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQ 1859
Query: 115 SG---EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASG 171
SG SG +G + ES + S H GE S H
Sbjct: 1860 SGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRH 1919
Query: 172 EQASGAPISSTSTG 185
+ G +T G
Sbjct: 1920 QTTHGQTGDTTEHG 1933
Score = 34.3 bits (77), Expect = 0.12
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 10/113 (8%)
Query: 50 SDAEALYETSSGLNTLSEHGS--SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGE 107
SD+E ++ S +T HG S+HG S+ V E H ++ T HA
Sbjct: 1657 SDSE-VHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDT------TRHAHYH 1709
Query: 108 HTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
H + Q +G + +G SG S+ E S HG GE S
Sbjct: 1710 HGLTTQ-TGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESES 1761
Score = 34.3 bits (77), Expect = 0.12
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 66 SEHGSSEHGSSKHTVAEHTS---GEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
+ HG S HG S T + T H+ES + A+ G HT + S SG
Sbjct: 2155 TRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSG-HTHSQAGSRHGQSGS 2213
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPS-GEQASGEQPSGEHASGEQASGAPISS 181
G Q + ++G D +G G+ G + +G + SG S + + S
Sbjct: 2214 SGHGRQGTTHGQTG----DTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSH 2269
Query: 182 TSTGTI 187
T +G I
Sbjct: 2270 THSGHI 2275
Score = 33.5 bits (75), Expect = 0.20
Identities = 28/107 (26%), Positives = 35/107 (32%), Gaps = 3/107 (2%)
Query: 56 YETSSGLNTLSE-HGSSEHGSSKHTVAEHTSGEHAESEHASGEPA-ATEHAEGEHTVGEQ 113
Y S G + +S H HG + E S H G+ A T H H Q
Sbjct: 1958 YSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQ 2017
Query: 114 PSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
G + +G SG S+ E S HG GE S
Sbjct: 2018 -RGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGS 2063
Score = 33.1 bits (74), Expect = 0.26
Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 31/147 (21%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAES-EHA-SGEPAATEHAEGEHTVGEQPSGEQPSGE- 122
S+HG S GSS H T G+ ++ HA SG +T+ G T G + SG S +
Sbjct: 2056 SQHGES--GSSVHERHGTTHGQTGDTTRHAHSGHGQSTQR--GSRTAGRRGSGHSESSDS 2111
Query: 123 ------------HLSGEQPLSELESGE-----------QPSDEQPSGEHGSGEQ-PSGEQ 158
H G+ ESG Q D G+ G G+ +G +
Sbjct: 2112 EVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSR 2171
Query: 159 ASGEQPSGEHASGEQASGAPISSTSTG 185
+G Q S S + + S T +G
Sbjct: 2172 TTGRQRSSHSESSDSEVHSEASPTHSG 2198
Score = 32.7 bits (73), Expect = 0.34
Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 12/116 (10%)
Query: 69 GSSEHGSSKHTVA---EHTSGEHAESEHAS-GEPAATEHAEGEH-TVGEQPSGEQPSGEH 123
G +HGSS + +H SG S G + G+H +V Q SG G+H
Sbjct: 465 GYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSG---FGQH 521
Query: 124 LSGEQPLSELESGEQPSDEQPSGEHGSGEQPS---GEQASGEQPS-GEHASGEQAS 175
S S E S + G+HGSG S G+ S E G+H G S
Sbjct: 522 GSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577
Score = 32.0 bits (71), Expect = 0.57
Identities = 45/176 (25%), Positives = 67/176 (38%), Gaps = 20/176 (11%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQL--PGEFFSLENPSDAEALYETSSGLNTLSEHGSS 71
G G SS + + H ++ ++L G S N ++ Y SS ++ S G
Sbjct: 137 GEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSG-GKD 195
Query: 72 EHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS 131
HGSS + E + H SGE E G ++ + G G SG
Sbjct: 196 RHGSSSVELRERINKSHISPSRESGE--EYESGSGSNSWERKGHGGLSCGLETSGH---- 249
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQAS---GAPISSTST 184
E S + EQ G SG SG ++ HA G S G P +++S+
Sbjct: 250 ESNSTQSRIREQKLGSSCSGSGDSGRRS--------HACGYSNSSGCGRPQNASSS 297
Score = 31.2 bits (69), Expect = 0.98
Identities = 44/160 (27%), Positives = 65/160 (40%), Gaps = 28/160 (17%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAAT---EHAE 105
S + + SG + +G E+GS +S E ++ ++ SG +T +H
Sbjct: 375 SQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGT 434
Query: 106 G--------EHTVGEQPSGEQPSGEHLS-GEQPLSELESGEQPSDEQPSGEHGSGEQPS- 155
G +H G SG Q G+H S Q L + G G+HGSG S
Sbjct: 435 GLSQSSGFEQHVCG---SG-QTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSS 490
Query: 156 --GEQASGEQPS---GEHAS-GEQASG----APISSTSTG 185
G+ SG S G+H S Q+SG +S S+G
Sbjct: 491 GFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSG 530
Score = 31.2 bits (69), Expect = 0.98
Identities = 28/95 (29%), Positives = 34/95 (35%), Gaps = 9/95 (9%)
Query: 68 HGS--SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
HG S+HG S TV G H + +G+ T HA H Q G +G S
Sbjct: 1447 HGQAGSQHGESGSTV----HGRHGTTHGQTGD--TTRHAHYHHGKSTQ-RGSSTTGRRGS 1499
Query: 126 GEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
G S+ E S HG GE S
Sbjct: 1500 GHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESES 1534
Score = 31.2 bits (69), Expect = 0.98
Identities = 44/170 (25%), Positives = 55/170 (32%), Gaps = 25/170 (14%)
Query: 14 GSARGTSSQPNELSGSIDHQ-----------TSVQQLPGEFFSLENPSDAEALYETSSGL 62
G G S + S SI H T+ G + + S TS
Sbjct: 1519 GHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSE 1578
Query: 63 NTLSEHGSSEHGSSKHTVAEHTSGE----HAESEHASGEPAATEHAEGEHTVGEQPSGEQ 118
+T SE S GS + EHT G+ H E E E T H + T G SG
Sbjct: 1579 STDSEVHSG--GSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHG 1636
Query: 119 PS---GEHLSGEQPLSELESGEQP-----SDEQPSGEHGSGEQPSGEQAS 160
S G +G Q S ES + S HG G+ S
Sbjct: 1637 QSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSES 1686
Score = 28.1 bits (61), Expect = 8.3
Identities = 37/175 (21%), Positives = 60/175 (34%), Gaps = 17/175 (9%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHG 74
S G S+Q + + + E S +P+ + + + S HG S G
Sbjct: 2160 SGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAG-----SRHGQS--G 2212
Query: 75 SSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE---HLSGEQPLS 131
SS H T G+ ++ + G T G + SG S + H G S
Sbjct: 2213 SSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHS 2272
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTGT 186
G+ S ++ G G + +G+ H+ Q ST TG+
Sbjct: 2273 GHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQ-------STQTGS 2320
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 46.6 bits (109), Expect = 2e-05
Identities = 35/145 (24%), Positives = 53/145 (36%), Gaps = 11/145 (7%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAE- 105
E P +E E G + E G A T G H E+E G P E +
Sbjct: 39 EGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQG 98
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELE---------SGEQPSDEQPSGEHGSGEQPSG 156
GE T G Q G GE P E + ++ ++++P GS +G
Sbjct: 99 GEETSGAQQVEGASPGRGAQGE-PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAG 157
Query: 157 EQASGEQPSGEHASGEQASGAPISS 181
+ E P G++ E +G + +
Sbjct: 158 DSVDAEGPLGDNIEAEGPAGDSVEA 182
Score = 43.9 bits (102), Expect = 1e-04
Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 18/145 (12%)
Query: 37 QQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASG 96
Q+ P + + E +AE E G S E G S AE G++ E+E +G
Sbjct: 126 QREPEDSAAPERQEEAEQRPEVPEG------SASGEAGDSVD--AEGPLGDNIEAEGPAG 177
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG 156
+ E E VG+ E P+G+ + E PL G+ E P+G+ E G
Sbjct: 178 DSV-----EAEGRVGDSVDAEGPAGDSVDAEGPL-----GDNIQAEGPAGDSVDAEGRVG 227
Query: 157 EQASGEQPSGEHASGEQASGAPISS 181
+ E P+G+ E G + +
Sbjct: 228 DSVDAEGPAGDSVDAEGRVGDSVEA 252
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/182 (22%), Positives = 72/182 (39%), Gaps = 19/182 (10%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLP-----------GEFFSLENPSDAEALYETSSGL 62
G RG + + E S + + Q +Q P G+ E P E +G
Sbjct: 119 GEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGD 178
Query: 63 NTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
+ +E + ++ + E ++ E A + + E VG+ E P+G+
Sbjct: 179 SVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGD 238
Query: 123 HLSGEQPLSE-LESGEQPSDEQ----PSGEHGSGEQPSGEQASGEQPSG--EHASGE-QA 174
+ E + + +E+G+ D P+G+ E P+G+ E P+G SGE Q
Sbjct: 239 SVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQ 298
Query: 175 SG 176
SG
Sbjct: 299 SG 300
Score = 32.0 bits (71), Expect = 0.57
Identities = 25/82 (30%), Positives = 30/82 (36%), Gaps = 5/82 (6%)
Query: 96 GEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPS 155
GEP A E E G + + E P G E + G + G HG E
Sbjct: 29 GEPGAAG-GEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEE 87
Query: 156 GEQASGEQPSGEHASGEQASGA 177
G E P G GE+ SGA
Sbjct: 88 GAPEGAEVPQG----GEETSGA 105
Score = 29.6 bits (65), Expect = 2.8
Identities = 38/170 (22%), Positives = 61/170 (35%), Gaps = 15/170 (8%)
Query: 16 ARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGS 75
A G E G + G+ E P+ E G N +E + +
Sbjct: 162 AEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVD 221
Query: 76 SKHTV-----AEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPL 130
++ V AE +G+ ++E G + E G+ P+G+ + E P
Sbjct: 222 AEGRVGDSVDAEGPAGDSVDAEGRVG-----DSVEAGDPAGDGVEAGVPAGDSVEAEGPA 276
Query: 131 SELESGEQPSDEQPSGEHGSGE-QPSGEQASGEQPSG-EHASGEQASGAP 178
+ E P+ SGE Q SG+ + Q E A+GE A +P
Sbjct: 277 GDSMDAEGPAGR---ARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSP 323
Score = 29.3 bits (64), Expect = 3.7
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 7/70 (10%)
Query: 114 PSGEQPSGEHLSGEQPLSELESGEQPSDEQPSG-----EHGSGEQPSGEQASGEQPSGEH 168
P E+P +G + +E G + ++E P G E G G G +A G H
Sbjct: 23 PLAERPGEPGAAGGE--AEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAH 80
Query: 169 ASGEQASGAP 178
E GAP
Sbjct: 81 GETEAEEGAP 90
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 46.2 bits (108), Expect = 3e-05
Identities = 44/169 (26%), Positives = 57/169 (33%), Gaps = 9/169 (5%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
G + E G + ++ GE E + E G G E
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGE------QPSGEQPSGEHLSGE 127
G + GE E E E EGE GE + GE+ GE GE
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE-WEGE 958
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASG 176
+ E E E+ E GE G GE+ GE GE+ GE E+ G
Sbjct: 959 EEEGEGEGEEEGEGEGEEGE-GEGEEEEGE-GEGEEEEGEEEGEEEGEG 1005
Score = 45.4 bits (106), Expect = 5e-05
Identities = 35/113 (30%), Positives = 49/113 (43%), Gaps = 9/113 (7%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
E E G K E G E EH GE + E E GE E+ GE + G
Sbjct: 711 EQKEREQGHQKERNQEMEEG--GEEEHGEGEEEEGDREEEEEKEGE--GKEEGEGEEVEG 766
Query: 127 EQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPI 179
E+ E E GE+ +E+ +G+ GE+ G+Q GE+ E E+ G +
Sbjct: 767 ER---EKEEGERKKEER-AGKEEKGEE-EGDQGEGEEEETEGRGEEKEEGGEV 814
Score = 43.9 bits (102), Expect = 1e-04
Identities = 34/105 (32%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 69 GSSEHGSSKHTVAEHTSGEHAES-EHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE 127
G+ E GSS AEH E E E G EGE + E+ ++ GE E
Sbjct: 657 GTCEEGSSG---AEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGE----E 709
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE 172
Q E E G Q Q E G E GE+ G++ E GE
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Score = 43.9 bits (102), Expect = 1e-04
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 16/121 (13%)
Query: 65 LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGE-QPSGEH 123
+ E G EHG E G+ E E GE E EGE GE+ E + E
Sbjct: 727 MEEGGEEEHGE-----GEEEEGDREEEEEKEGE--GKEEGEGEEVEGEREKEEGERKKEE 779
Query: 124 LSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG--------EHASGEQAS 175
+G++ E E + +E+ + G ++ GE GE G E GE+
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Query: 176 G 176
G
Sbjct: 840 G 840
Score = 43.5 bits (101), Expect = 2e-04
Identities = 42/162 (25%), Positives = 58/162 (35%), Gaps = 14/162 (8%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
G + E G + +++ GE + E E +G E E G
Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGE----REKEEGERKKEERAG----KEEKGEEEGDQG 794
Query: 78 HTVAEHTSGEHAESEHASG-EPAATEHAEGEHTVGEQPS-GEQPSGEHLSGEQPLSELES 135
E T G E E E E +GE E+ GE+ GE GE+ E E
Sbjct: 795 EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE---GEEEEGEGEE 851
Query: 136 GEQPSDEQPSGEHGSGEQPSGE-QASGEQPSGEHASGEQASG 176
E + GE G GE+ E + GE+ GE E+ G
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG 893
Score = 42.7 bits (99), Expect = 3e-04
Identities = 39/132 (29%), Positives = 48/132 (36%), Gaps = 12/132 (9%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
E E E + G E G G V E E E GE E EG
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEGGEVEGGE---VEEGKGEREEEEEEGEGEE---EEGEG 842
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQP 164
E GE GE+ GE GE+ E E E+ + + G E G GE + GE+
Sbjct: 843 EEEEGE---GEEEEGEG-KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898
Query: 165 SGEHASGEQASG 176
GE E+ G
Sbjct: 899 EGEGEGEEEGEG 910
Score = 41.6 bits (96), Expect = 7e-04
Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 11/107 (10%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
E G E G + E E E E GE E EGE GE E+ GE G
Sbjct: 815 EGGEVEEGKGEREEEE----EEGEGEEEEGE-GEEEEGEGEEEEGEGKGEEE--GEEGEG 867
Query: 127 EQPLSELES-GEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE 172
E+ E E GE+ E E G GE GE+ GE E GE
Sbjct: 868 EEEGEEGEGEGEEEEGEGEGEEEGEGE---GEEEEGEGEGEEEGEGE 911
Score = 40.8 bits (94), Expect = 0.001
Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 10/167 (5%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSE-HGSSEHGS 75
+G + E + + ++ GE E E E G E G E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 76 SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGE---QPSGEQPSGEHLSGEQPLSE 132
+ E GE E E GE EGE GE + GE+ GE E+ E
Sbjct: 883 GEGEGEEEGEGE-GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG-EEEEGEGE 940
Query: 133 LESGEQPSDEQPS---GEHGSGEQPSGEQASGEQPSGEHASGEQASG 176
E GE +E+ GE GE E+ GE GE GE+ G
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE-GEGEEEEG 986
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/136 (30%), Positives = 50/136 (36%), Gaps = 12/136 (8%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
E + E E G E G G + E GE + E GE E EG
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE---EEGEGEGEDGE-GEGEEEEGEW-EG 957
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELE---SGEQPSDEQPSGEHGSGEQPSGEQASGEQ 163
E GE E+ GE GE E E GE+ E+ E G GE+ GE E+
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE-EGEGEGEEE 1016
Query: 164 PSGE---HASGEQASG 176
GE GE+ G
Sbjct: 1017 EEGEVEGEVEGEEGEG 1032
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/119 (29%), Positives = 46/119 (38%), Gaps = 14/119 (11%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
EHG E E GE E E EGE E+ +G++ GE G
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK-KEERAGKEEKGEE-EG 791
Query: 127 EQPLSELESGEQPSDEQPSG--------EHGSGE-QPSGEQASGEQPSGEHASGEQASG 176
+Q E E E +E+ G E G GE + E+ GE+ GE GE+ G
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE---GEEEEG 847
Score = 37.7 bits (86), Expect = 0.010
Identities = 43/170 (25%), Positives = 54/170 (31%), Gaps = 22/170 (12%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
G + E G + + GE E + + E G E G
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 78 HTVAEHTSGEHAESEHASGEPAATEHAEGE-------------HTVGEQPSGEQPSGEHL 124
E GE E E GE E EGE GE+ GE+ E
Sbjct: 945 EGEGEEEEGEW-EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEG 1003
Query: 125 SGEQPLSELESGEQPSDEQPSGE-HGSGEQPSGEQASGEQPSGEHASGEQ 173
GE E GE +E+ GE G E GE GE+ GE E+
Sbjct: 1004 EGE------EEGEGEGEEEEEGEVEGEVEGEEGE-GEGEEEEGEEEGEER 1046
Score = 34.3 bits (77), Expect = 0.12
Identities = 29/115 (25%), Positives = 42/115 (36%), Gaps = 4/115 (3%)
Query: 65 LSEHGSSEHGSSKHTVAEHTSGEHAESEHA--SGEPAATEHAEGEHTVGEQPSGEQPSGE 122
L++ G +K +V E G + G A + E GE+ G
Sbjct: 630 LTDKAEVSEGKAK-SVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688
Query: 123 HLSGEQPLSELESGEQ-PSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASG 176
GE+ L+E E ++ +EQ E G Q Q E EH GE+ G
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG 743
Score = 33.9 bits (76), Expect = 0.15
Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 5/112 (4%)
Query: 69 GSSEHGSSKHTVAEHTSGEHAESEHASGEPAAT-EHAEGEHTVGEQPSGEQPSGEHLSGE 127
G E G + GE E E E E EGE E+ GE+ GE E
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE-EGEGEGEE 1015
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGE---QASGEQPSGEHASGEQASG 176
+ E+E + + + GE GE+ E + GE+ E+ G
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067
Score = 33.1 bits (74), Expect = 0.26
Identities = 36/144 (25%), Positives = 51/144 (35%), Gaps = 7/144 (4%)
Query: 31 DHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAE-HTSGEHA 89
D + ++ GE+ E + E E G E G + E GE
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 90 ESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHG 149
GE E EGE V + GE+ GE GE+ E E GE+ E E+
Sbjct: 1003 GEGEEEGEGEGEEEEEGE--VEGEVEGEEGEGE---GEEEEGE-EEGEEREKEGEGEENR 1056
Query: 150 SGEQPSGEQASGEQPSGEHASGEQ 173
+ E+ Q +GE + Q
Sbjct: 1057 RNREEEEEEEGKYQETGEEENERQ 1080
Score = 32.3 bits (72), Expect = 0.44
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
G + +AE + + E E E +G Q E EH GE+
Sbjct: 690 GEGEKELAEKEEWKKRDGE----EQEQKEREQGHQKERNQEMEEGGEEEHGEGEE----- 740
Query: 134 ESGEQPSDEQPSG---EHGSGEQPSG--EQASGEQPSGEHASGEQ 173
E G++ +E+ G E G GE+ G E+ GE+ E A E+
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Score = 29.3 bits (64), Expect = 3.7
Identities = 29/122 (23%), Positives = 44/122 (36%), Gaps = 5/122 (4%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES-EHASGEPAATEHAEGEHTVGEQPS 115
E G + G E ++ + GE E E G E E
Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Query: 116 GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGE-QPSGEQASGEQPSGEHASGEQA 174
GE+ G+ E+ E E E+ E+ GE E + E+ +G++ GE G+Q
Sbjct: 738 GEEEEGDREEEEE--KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE-EGDQG 794
Query: 175 SG 176
G
Sbjct: 795 EG 796
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 43.1 bits (100), Expect = 2e-04
Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 34/198 (17%)
Query: 5 LLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT 64
+L S +G G S L S+ + LP E + ++SG+
Sbjct: 1342 VLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPS----------GEVVETSASGIED 1391
Query: 65 LSEHGSSE----HGSSKHTVAEHTSGEHAESEHASG-----------EPAATEHAEGEHT 109
+SE S E S ++ SGE ASG E T +E
Sbjct: 1392 VSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTD 1451
Query: 110 VGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP----- 164
+ PSG + SG + LS L SG++ SG+ G+ PSG SG+ P
Sbjct: 1452 LSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGL 1511
Query: 165 ----SGEHASGEQASGAP 178
SGE++ + SG P
Sbjct: 1512 PSGFSGEYSGVDLGSGPP 1529
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 18/144 (12%)
Query: 61 GLNTLSEHGSSEHG---SSKHTVAEHTSGEHAESE---HASGEPAATEHAEGEHTVGEQP 114
G T+ G+ E SS+ ++ SG + +E ASG P + G V QP
Sbjct: 1566 GRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQP 1625
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG-EQASGE---------QP 164
SG + SG LS L SG+ + SG QP G SGE QP
Sbjct: 1626 SGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP 1685
Query: 165 SGEHASGEQASGAP--ISSTSTGT 186
SG SG P +S T++G+
Sbjct: 1686 SGLPGFSGATSGVPDLVSGTTSGS 1709
Score = 37.7 bits (86), Expect = 0.010
Identities = 46/170 (27%), Positives = 65/170 (38%), Gaps = 12/170 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
GT+S E SG TS+ ++ F E + L SG LS S +
Sbjct: 1704 GTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ 1763
Query: 78 HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS------ 131
+ +SG +++ SG P+ GE + E S PSG + P S
Sbjct: 1764 FSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGS-SLPSGAYYGSGTPSSFPTVSL 1822
Query: 132 ----ELESGEQPSDEQPSGEHGSG-EQPSGEQASGEQPSGEHASGEQASG 176
+ES Q Q +GE SG + SG + SGEH+ SG
Sbjct: 1823 VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSG 1872
Score = 37.4 bits (85), Expect = 0.014
Identities = 48/176 (27%), Positives = 62/176 (35%), Gaps = 18/176 (10%)
Query: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENP----SDAEALYETSSGLNTLSEH 68
L G + SG++D Q P EF L + S + E S L + + +
Sbjct: 1751 LSGKSGMVDVSGQFSGTVDSSGFTSQTP-EFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809
Query: 69 GSSEHGSSK------HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
GS S T+ E + E G P+ G H+ SGE
Sbjct: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGAHSGAPDMSGEHSGFL 1868
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAP 178
LSG Q SGE P SG+ S SGE + SGE ASG P
Sbjct: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGE------ASGLP 1918
Score = 35.4 bits (80), Expect = 0.052
Identities = 43/120 (35%), Positives = 48/120 (40%), Gaps = 22/120 (18%)
Query: 85 SGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQ---------------PSGEHL----S 125
SG ES SG+ E TVGE PSG + PSGE L S
Sbjct: 910 SGLPVESGLPSGDEERIEWPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSAS 968
Query: 126 GEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
G LS L SGE P E SG PSGE P E SG SG + +T+ G
Sbjct: 969 GVGDLSGLPSGEVLETTAPGVEDISG-LPSGEVLETTAPGVEDISG-LPSGEVLETTAPG 1026
Score = 32.3 bits (72), Expect = 0.44
Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 5/109 (4%)
Query: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSG---EHLSGEQPLSELESGEQPS 140
+SGE + + SG+ + G Q SG++ SG L S + SG
Sbjct: 856 SSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVE 915
Query: 141 DEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASG-APISSTSTGTIL 188
PSG+ E PS GE PSG ASG +S +G +L
Sbjct: 916 SGLPSGDEERIEWPS-TPTVGELPSGAEILEGSASGVGDLSGLPSGEVL 963
Score = 30.4 bits (67), Expect = 1.7
Identities = 47/175 (26%), Positives = 63/175 (36%), Gaps = 19/175 (10%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
G A TS P+ SG + G PS SG T+S S+
Sbjct: 1503 GQAPETSGLPSGFSG---------EYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLV 1553
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
+ A G +GE + +E + + + SG PSG LSG+ S
Sbjct: 1554 EVVTASTASELEGRGTIGISGAGEISGLPSSELD--ISGRASG-LPSGTELSGQASGSPD 1610
Query: 134 ESGEQPSDEQPSGEHGSGEQPSG-EQASGEQPSGEHASGEQASGAPISSTSTGTI 187
SGE P G G QPSG SGE SG + IS ++G +
Sbjct: 1611 VSGEIP------GLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVL 1659
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 43.1 bits (100), Expect = 2e-04
Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 34/198 (17%)
Query: 5 LLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT 64
+L S +G G S L S+ + LP E + ++SG+
Sbjct: 1342 VLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPS----------GEVVETSASGIED 1391
Query: 65 LSEHGSSE----HGSSKHTVAEHTSGEHAESEHASG-----------EPAATEHAEGEHT 109
+SE S E S ++ SGE ASG E T +E
Sbjct: 1392 VSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTD 1451
Query: 110 VGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP----- 164
+ PSG + SG + LS L SG++ SG+ G+ PSG SG+ P
Sbjct: 1452 LSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGL 1511
Query: 165 ----SGEHASGEQASGAP 178
SGE++ + SG P
Sbjct: 1512 PSGFSGEYSGVDLGSGPP 1529
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 18/144 (12%)
Query: 61 GLNTLSEHGSSEHG---SSKHTVAEHTSGEHAESE---HASGEPAATEHAEGEHTVGEQP 114
G T+ G+ E SS+ ++ SG + +E ASG P + G V QP
Sbjct: 1566 GRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQP 1625
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG-EQASGE---------QP 164
SG + SG LS L SG+ + SG QP G SGE QP
Sbjct: 1626 SGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP 1685
Query: 165 SGEHASGEQASGAP--ISSTSTGT 186
SG SG P +S T++G+
Sbjct: 1686 SGLPGFSGATSGVPDLVSGTTSGS 1709
Score = 37.7 bits (86), Expect = 0.010
Identities = 46/170 (27%), Positives = 65/170 (38%), Gaps = 12/170 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
GT+S E SG TS+ ++ F E + L SG LS S +
Sbjct: 1704 GTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ 1763
Query: 78 HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS------ 131
+ +SG +++ SG P+ GE + E S PSG + P S
Sbjct: 1764 FSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGS-SLPSGAYYGSGTPSSFPTVSL 1822
Query: 132 ----ELESGEQPSDEQPSGEHGSG-EQPSGEQASGEQPSGEHASGEQASG 176
+ES Q Q +GE SG + SG + SGEH+ SG
Sbjct: 1823 VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSG 1872
Score = 37.4 bits (85), Expect = 0.014
Identities = 48/176 (27%), Positives = 62/176 (35%), Gaps = 18/176 (10%)
Query: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENP----SDAEALYETSSGLNTLSEH 68
L G + SG++D Q P EF L + S + E S L + + +
Sbjct: 1751 LSGKSGMVDVSGQFSGTVDSSGFTSQTP-EFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809
Query: 69 GSSEHGSSK------HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
GS S T+ E + E G P+ G H+ SGE
Sbjct: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGAHSGAPDMSGEHSGFL 1868
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAP 178
LSG Q SGE P SG+ S SGE + SGE ASG P
Sbjct: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGE------ASGLP 1918
Score = 35.4 bits (80), Expect = 0.052
Identities = 43/120 (35%), Positives = 48/120 (40%), Gaps = 22/120 (18%)
Query: 85 SGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQ---------------PSGEHL----S 125
SG ES SG+ E TVGE PSG + PSGE L S
Sbjct: 910 SGLPVESGLPSGDEERIEWPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSAS 968
Query: 126 GEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
G LS L SGE P E SG PSGE P E SG SG + +T+ G
Sbjct: 969 GVGDLSGLPSGEVLETTAPGVEDISG-LPSGEVLETTAPGVEDISG-LPSGEVLETTAPG 1026
Score = 32.3 bits (72), Expect = 0.44
Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 5/109 (4%)
Query: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSG---EHLSGEQPLSELESGEQPS 140
+SGE + + SG+ + G Q SG++ SG L S + SG
Sbjct: 856 SSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVE 915
Query: 141 DEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASG-APISSTSTGTIL 188
PSG+ E PS GE PSG ASG +S +G +L
Sbjct: 916 SGLPSGDEERIEWPS-TPTVGELPSGAEILEGSASGVGDLSGLPSGEVL 963
Score = 30.4 bits (67), Expect = 1.7
Identities = 47/175 (26%), Positives = 63/175 (36%), Gaps = 19/175 (10%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
G A TS P+ SG + G PS SG T+S S+
Sbjct: 1503 GQAPETSGLPSGFSG---------EYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLV 1553
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
+ A G +GE + +E + + + SG PSG LSG+ S
Sbjct: 1554 EVVTASTASELEGRGTIGISGAGEISGLPSSELD--ISGRASG-LPSGTELSGQASGSPD 1610
Query: 134 ESGEQPSDEQPSGEHGSGEQPSG-EQASGEQPSGEHASGEQASGAPISSTSTGTI 187
SGE P G G QPSG SGE SG + IS ++G +
Sbjct: 1611 VSGEIP------GLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVL 1659
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 42.4 bits (98), Expect = 4e-04
Identities = 48/164 (29%), Positives = 70/164 (42%), Gaps = 15/164 (9%)
Query: 22 QPNELSGSIDHQTSVQQLPGEFFS-LENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
+ EL S +T ++ P EF S L + AE L ++ +
Sbjct: 436 EARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPL 495
Query: 81 AEHTSGE--HAESEHASGEPAATEHAEGEHTVG---EQPSGEQPSGEHLSGEQPLSELES 135
+E TS E HAE + E E A E + E P+ E P+ + PLSE S
Sbjct: 496 SEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA----EAQSPLSEETS 551
Query: 136 GEQ-PSDEQ-PSGEHGSGEQPSGEQASGEQPSGEHASGEQASGA 177
E+ P++ Q PS + S E+ E + PSGE + E+AS A
Sbjct: 552 AEEAPAEVQSPSAKGVSIEEAPLEL---QPPSGEETTAEEASAA 592
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 5/142 (3%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + +G + + SG + +G + S +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239
Query: 166 GEHASGEQASGAPISSTSTGTI 187
G + G+ + ST ++
Sbjct: 1240 GSETNTAFIIGSETTIASTASL 1261
Score = 33.1 bits (74), Expect = 0.26
Identities = 29/171 (16%), Positives = 61/171 (35%), Gaps = 5/171 (2%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+G + + G + +G + + +G + G+ ++ +T
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038
Score = 32.3 bits (72), Expect = 0.44
Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 4/131 (3%)
Query: 58 TSSGLNTLSEHGS----SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQ 113
T+S T+S GS + S+ T T G + G T E T
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 114 PSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQ 173
G + + G + + G + + G + +G + + G +
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937
Query: 174 ASGAPISSTST 184
G+ +++ ST
Sbjct: 938 TEGSELTTVST 948
Score = 31.6 bits (70), Expect = 0.75
Identities = 24/141 (17%), Positives = 49/141 (34%), Gaps = 3/141 (2%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSS---KHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + T S T+S GS + T T+G + +G T EG
Sbjct: 941 SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEG 1000
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
T +G + + +G + G + + +G + +G + + G
Sbjct: 1001 SETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG 1060
Query: 167 EHASGEQASGAPISSTSTGTI 187
+ +G+ ++ ST +
Sbjct: 1061 SETTTVSTTGSETTTASTADL 1081
Score = 31.2 bits (69), Expect = 0.98
Identities = 27/140 (19%), Positives = 52/140 (37%), Gaps = 7/140 (5%)
Query: 50 SDAEALYETSSGLNTLSEHGS-----SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHA 104
S+ + T S T+S G+ S GS TV T+G + + +G T
Sbjct: 1001 SETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTST 1058
Query: 105 EGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP 164
EG T +G + + + + + SG + +G + +G + +
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118
Query: 165 SGEHASGEQASGAPISSTST 184
G A+ + + ++ ST
Sbjct: 1119 EGSEATTVSTTSSETTTAST 1138
Score = 29.3 bits (64), Expect = 3.7
Identities = 23/138 (16%), Positives = 47/138 (34%), Gaps = 3/138 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 EHASGEQASGAPISSTST 184
+ + + ++ ST
Sbjct: 591 SETTTVSTADSENTTAST 608
Score = 28.9 bits (63), Expect = 4.8
Identities = 34/152 (22%), Positives = 54/152 (35%), Gaps = 20/152 (13%)
Query: 50 SDAEALYETSSGLNTLSEHGS-----SEHGSSKHTVAE--------HTSGEHAESEHASG 96
S+ A+ T S + T+S GS S GS TV+ T G + +G
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTG 570
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG 156
T+ EG T +G + + + SE + E S E +
Sbjct: 571 AETTTDSTEGSGTTAASTAGSETTTVSTAD----SENTTASTADSETTSASTTGSETTTA 626
Query: 157 EQASGEQPSGEHASGEQASGAPISSTSTGTIL 188
S E + AS E + +S+T + T +
Sbjct: 627 STTSSETTT---ASTEGSETTTVSTTDSETTM 655
Score = 28.9 bits (63), Expect = 4.8
Identities = 25/158 (15%), Positives = 49/158 (31%), Gaps = 23/158 (14%)
Query: 50 SDAEALYETSSGLNTLSEHGSSE-----------------------HGSSKHTVAEHTSG 86
S+ A+Y T S T S GS S T T+G
Sbjct: 1041 SETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 87 EHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSG 146
+ + +G T EG + + + +G + + + + + G
Sbjct: 1101 SETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIG 1160
Query: 147 EHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+ +G +A+ G + +G+ ++ ST
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST 1198
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 5/142 (3%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + +G + + SG + +G + S +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239
Query: 166 GEHASGEQASGAPISSTSTGTI 187
G + G+ + ST ++
Sbjct: 1240 GSETNTAFIIGSETTIASTASL 1261
Score = 33.1 bits (74), Expect = 0.26
Identities = 29/171 (16%), Positives = 61/171 (35%), Gaps = 5/171 (2%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+G + + G + +G + + +G + G+ ++ +T
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038
Score = 32.3 bits (72), Expect = 0.44
Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 4/131 (3%)
Query: 58 TSSGLNTLSEHGS----SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQ 113
T+S T+S GS + S+ T T G + G T E T
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 114 PSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQ 173
G + + G + + G + + G + +G + + G +
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937
Query: 174 ASGAPISSTST 184
G+ +++ ST
Sbjct: 938 TEGSELTTVST 948
Score = 31.6 bits (70), Expect = 0.75
Identities = 24/141 (17%), Positives = 49/141 (34%), Gaps = 3/141 (2%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSS---KHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + T S T+S GS + T T+G + +G T EG
Sbjct: 941 SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEG 1000
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
T +G + + +G + G + + +G + +G + + G
Sbjct: 1001 SETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG 1060
Query: 167 EHASGEQASGAPISSTSTGTI 187
+ +G+ ++ ST +
Sbjct: 1061 SETTTVSTTGSETTTASTADL 1081
Score = 31.2 bits (69), Expect = 0.98
Identities = 27/140 (19%), Positives = 52/140 (37%), Gaps = 7/140 (5%)
Query: 50 SDAEALYETSSGLNTLSEHGS-----SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHA 104
S+ + T S T+S G+ S GS TV T+G + + +G T
Sbjct: 1001 SETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTST 1058
Query: 105 EGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP 164
EG T +G + + + + + SG + +G + +G + +
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118
Query: 165 SGEHASGEQASGAPISSTST 184
G A+ + + ++ ST
Sbjct: 1119 EGSEATTVSTTSSETTTAST 1138
Score = 29.3 bits (64), Expect = 3.7
Identities = 23/138 (16%), Positives = 47/138 (34%), Gaps = 3/138 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 EHASGEQASGAPISSTST 184
+ + + ++ ST
Sbjct: 591 SETTTVSTADSENTTAST 608
Score = 28.9 bits (63), Expect = 4.8
Identities = 34/152 (22%), Positives = 54/152 (35%), Gaps = 20/152 (13%)
Query: 50 SDAEALYETSSGLNTLSEHGS-----SEHGSSKHTVAE--------HTSGEHAESEHASG 96
S+ A+ T S + T+S GS S GS TV+ T G + +G
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTG 570
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG 156
T+ EG T +G + + + SE + E S E +
Sbjct: 571 AETTTDSTEGSGTTAASTAGSETTTVSTAD----SENTTASTADSETTSASTTGSETTTA 626
Query: 157 EQASGEQPSGEHASGEQASGAPISSTSTGTIL 188
S E + AS E + +S+T + T +
Sbjct: 627 STTSSETTT---ASTEGSETTTVSTTDSETTM 655
Score = 28.9 bits (63), Expect = 4.8
Identities = 25/158 (15%), Positives = 49/158 (31%), Gaps = 23/158 (14%)
Query: 50 SDAEALYETSSGLNTLSEHGSSE-----------------------HGSSKHTVAEHTSG 86
S+ A+Y T S T S GS S T T+G
Sbjct: 1041 SETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 87 EHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSG 146
+ + +G T EG + + + +G + + + + + G
Sbjct: 1101 SETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIG 1160
Query: 147 EHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+ +G +A+ G + +G+ ++ ST
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST 1198
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 5/142 (3%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + +G + + SG + +G + S +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239
Query: 166 GEHASGEQASGAPISSTSTGTI 187
G + G+ + ST ++
Sbjct: 1240 GSETNTAFIIGSETTIASTASL 1261
Score = 33.1 bits (74), Expect = 0.26
Identities = 29/171 (16%), Positives = 61/171 (35%), Gaps = 5/171 (2%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+G + + G + +G + + +G + G+ ++ +T
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038
Score = 32.3 bits (72), Expect = 0.44
Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 4/131 (3%)
Query: 58 TSSGLNTLSEHGS----SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQ 113
T+S T+S GS + S+ T T G + G T E T
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 114 PSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQ 173
G + + G + + G + + G + +G + + G +
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937
Query: 174 ASGAPISSTST 184
G+ +++ ST
Sbjct: 938 TEGSELTTVST 948
Score = 31.6 bits (70), Expect = 0.75
Identities = 24/141 (17%), Positives = 49/141 (34%), Gaps = 3/141 (2%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSS---KHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + T S T+S GS + T T+G + +G T EG
Sbjct: 941 SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEG 1000
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
T +G + + +G + G + + +G + +G + + G
Sbjct: 1001 SETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG 1060
Query: 167 EHASGEQASGAPISSTSTGTI 187
+ +G+ ++ ST +
Sbjct: 1061 SETTTVSTTGSETTTASTADL 1081
Score = 31.2 bits (69), Expect = 0.98
Identities = 27/140 (19%), Positives = 52/140 (37%), Gaps = 7/140 (5%)
Query: 50 SDAEALYETSSGLNTLSEHGS-----SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHA 104
S+ + T S T+S G+ S GS TV T+G + + +G T
Sbjct: 1001 SETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTST 1058
Query: 105 EGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP 164
EG T +G + + + + + SG + +G + +G + +
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118
Query: 165 SGEHASGEQASGAPISSTST 184
G A+ + + ++ ST
Sbjct: 1119 EGSEATTVSTTSSETTTAST 1138
Score = 29.3 bits (64), Expect = 3.7
Identities = 23/138 (16%), Positives = 47/138 (34%), Gaps = 3/138 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 EHASGEQASGAPISSTST 184
+ + + ++ ST
Sbjct: 591 SETTTVSTADSENTTAST 608
Score = 28.9 bits (63), Expect = 4.8
Identities = 34/152 (22%), Positives = 54/152 (35%), Gaps = 20/152 (13%)
Query: 50 SDAEALYETSSGLNTLSEHGS-----SEHGSSKHTVAE--------HTSGEHAESEHASG 96
S+ A+ T S + T+S GS S GS TV+ T G + +G
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTG 570
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG 156
T+ EG T +G + + + SE + E S E +
Sbjct: 571 AETTTDSTEGSGTTAASTAGSETTTVSTAD----SENTTASTADSETTSASTTGSETTTA 626
Query: 157 EQASGEQPSGEHASGEQASGAPISSTSTGTIL 188
S E + AS E + +S+T + T +
Sbjct: 627 STTSSETTT---ASTEGSETTTVSTTDSETTM 655
Score = 28.9 bits (63), Expect = 4.8
Identities = 25/158 (15%), Positives = 49/158 (31%), Gaps = 23/158 (14%)
Query: 50 SDAEALYETSSGLNTLSEHGSSE-----------------------HGSSKHTVAEHTSG 86
S+ A+Y T S T S GS S T T+G
Sbjct: 1041 SETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 87 EHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSG 146
+ + +G T EG + + + +G + + + + + G
Sbjct: 1101 SETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIG 1160
Query: 147 EHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+ +G +A+ G + +G+ ++ ST
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST 1198
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 41.6 bits (96), Expect = 7e-04
Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 6/120 (5%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
+++ SS +S H A ++GE S H ++ H+ H G+ S + SG S
Sbjct: 685 TQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH--GQASSAVRDSGHRGS 742
Query: 126 GEQPLSELESGEQPSDEQPSGEHG-SGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
++ E + SD Q HG +G Q S SGE + + SG+ + ST
Sbjct: 743 SGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERS---RRSGSFLYQVST 799
Score = 38.9 bits (89), Expect = 0.005
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 5/167 (2%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
GS+R + E +GS + + + S + D+E E++S + S S H
Sbjct: 1569 GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRH 1628
Query: 74 GS---SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPL 130
GS H + G AES SG A + G+ ++ + P H S Q
Sbjct: 1629 GSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQS 1688
Query: 131 SELESGEQPSDEQPSGEHG-SGEQ-PSGEQASGEQPSGEHASGEQAS 175
++ + Q S G SG + SG QAS + E + + S
Sbjct: 1689 ADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS 1735
Score = 37.0 bits (84), Expect = 0.018
Identities = 44/168 (26%), Positives = 63/168 (37%), Gaps = 27/168 (16%)
Query: 45 SLENPSDAEALYETS---SGLNTLSEHGSSEHGS---SKHTVAEHTS----GEHAESEHA 94
S+ SD+E E S SG + + GS++ S S+H + H G A+S
Sbjct: 945 SVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQ 1004
Query: 95 SGEP---------AATEHAEGEHTVGE------QPSGEQPSGEHLSGEQPLSEL-ESGE- 137
SG P AA+ H + + GE Q S + + Q S + +SG
Sbjct: 1005 SGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHW 1064
Query: 138 QPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
S Q S G E+ + SG G H Q S S +G
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSG 1112
Score = 37.0 bits (84), Expect = 0.018
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 17/146 (11%)
Query: 57 ETSSGLNTLSEHGSS---EHGSSKHTV-AEHTSGEHAESEHASGEPAATE-------HAE 105
E SSG T GSS + S +H+ +E SG + + H S + + H E
Sbjct: 1255 EQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQE 1314
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQA--SG-- 161
+ G + SG H + + S + + P HGS Q S + + SG
Sbjct: 1315 DRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIG 1374
Query: 162 --EQPSGEHASGEQASGAPISSTSTG 185
+ S SG + S + S G
Sbjct: 1375 HRQASSAVRDSGHRGSSGSQVTNSEG 1400
Score = 35.8 bits (81), Expect = 0.040
Identities = 45/183 (24%), Positives = 68/183 (37%), Gaps = 25/183 (13%)
Query: 16 ARGTSSQPNELSGSI--DHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
++G S SGS +H+ S Q+ S + + +E +G +E SS
Sbjct: 3545 SQGHSEDSERWSGSASRNHRGSAQEQ-----SRDGSRHPTSHHEDRAGHGHSAE--SSRQ 3597
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTV------------GEQPSGEQPSG 121
+ H AE++SG A S H +A E H G+ S + SG
Sbjct: 3598 SGTHH--AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3655
Query: 122 EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISS 181
S S+ E + SD Q H G+ +Q+ E G A SG+ +
Sbjct: 3656 HRGSSGSQASDSEGHSEDSDTQSVSAH--GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 3713
Query: 182 TST 184
ST
Sbjct: 3714 VST 3716
Score = 35.4 bits (80), Expect = 0.052
Identities = 47/157 (29%), Positives = 63/157 (40%), Gaps = 41/157 (26%)
Query: 45 SLENPSDAEALYETS---SGLNTLSEHGSSEHGS---SKHTVAEHTS----GEHAESEHA 94
S+ SD+E E S SG + + HGS++ S S+H + H G AES
Sbjct: 2242 SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ 2301
Query: 95 SGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQP 154
SG T HAE SG Q + H EQ S +GE+ HGS Q
Sbjct: 2302 SG----THHAENS-------SGGQAASSH---EQARSS--AGER---------HGSHHQQ 2336
Query: 155 SGEQA------SGEQPSGEHASGEQASGAPISSTSTG 185
S + + G+ S SG + S +S S G
Sbjct: 2337 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEG 2373
Score = 35.4 bits (80), Expect = 0.052
Identities = 45/183 (24%), Positives = 66/183 (36%), Gaps = 25/183 (13%)
Query: 16 ARGTSSQPNELSGSI--DHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
+ G S SGS +H S Q+ S + + +E +G +E SS
Sbjct: 2249 SEGHSEDSERRSGSASRNHHGSAQEQ-----SRDGSRHPRSHHEDRAGHGHSAE--SSRQ 2301
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTV------------GEQPSGEQPSG 121
+ H AE++SG A S H +A E H G+ S + SG
Sbjct: 2302 SGTHH--AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 2359
Query: 122 EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISS 181
S S+ E + SD Q H G+ +Q+ E G A SG+ +
Sbjct: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAH--GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 2417
Query: 182 TST 184
ST
Sbjct: 2418 VST 2420
Score = 35.0 bits (79), Expect = 0.068
Identities = 27/119 (22%), Positives = 46/119 (38%), Gaps = 9/119 (7%)
Query: 55 LYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
LY+ SS E S HG + + H ++ ++S A+ + G+ T+ P
Sbjct: 1442 LYQVSS-----HEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQD---GQDTIRGHP 1493
Query: 115 SGEQPSGEHLSGEQPLSEL-ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGE 172
+ + EQ + SG S P G + SG +++ Q E SG+
Sbjct: 1494 GSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGD 1552
Score = 34.7 bits (78), Expect = 0.088
Identities = 28/142 (19%), Positives = 53/142 (37%), Gaps = 9/142 (6%)
Query: 32 HQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES 91
HQ S Q+ ++ + +Y+ S+ E S HG ++ + H ++
Sbjct: 1095 HQQSHQESARDWSGGRSGRSGSFIYQVST-----HEQSESAHGRTRTSTGRRQGSHHEQA 1149
Query: 92 EHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL-ESGEQPSDEQPSGEHGS 150
+S A+ EG+ T+ P + + EQ + SG S G +
Sbjct: 1150 RDSSRHSAS---QEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA 1206
Query: 151 GEQPSGEQASGEQPSGEHASGE 172
SG +++ Q + SG+
Sbjct: 1207 SHGQSGSRSASRQTRKDKQSGD 1228
Score = 34.7 bits (78), Expect = 0.088
Identities = 42/180 (23%), Positives = 64/180 (35%), Gaps = 14/180 (7%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSE----HG- 69
++R S ++ S S H ++ G + S E L + S + E HG
Sbjct: 2559 TSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGH 2618
Query: 70 ---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
SS ++HT + +SG A S H +A E H S G G
Sbjct: 2619 SADSSRQSGTRHT--QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---G 2673
Query: 127 EQPLSELESGEQP-SDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
+ + +SG + S Q S G E + S +G H Q S S ++G
Sbjct: 2674 QASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSG 2733
Score = 34.7 bits (78), Expect = 0.088
Identities = 42/179 (23%), Positives = 63/179 (35%), Gaps = 14/179 (7%)
Query: 16 ARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSE----HG-- 69
+R S ++ S S H ++ G + S E L + S + E HG
Sbjct: 2884 SRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHS 2943
Query: 70 --SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE 127
SS ++HT + +SG A S H +A E H S G G+
Sbjct: 2944 ADSSRQSGTRHT--QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQ 2998
Query: 128 QPLSELESGEQP-SDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
+ +SG + S Q S G E + S +G H Q S S ++G
Sbjct: 2999 ASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSG 3057
Score = 34.7 bits (78), Expect = 0.088
Identities = 51/209 (24%), Positives = 76/209 (36%), Gaps = 39/209 (18%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEF----------FSLENPSDAEALYETS---SG 61
S+R + S+ +E S D Q + G+ S+ SD+E E S SG
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSG 3233
Query: 62 LNTLSEHGS----SEHGSSKHTVAEHTS----GEHAE---------SEHASGEPAATEHA 104
+ + GS S HGS +H + H G A+ +E +SG AA+ H
Sbjct: 3234 SASRNHRGSVQEQSRHGS-RHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHE 3292
Query: 105 EGEHTVGE------QPSGEQPSGEHLSGEQPLSELESGEQ--PSDEQPSGEHGSGEQPSG 156
+ + GE Q S + + Q S + S Q S G E+
Sbjct: 3293 QARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDT 3352
Query: 157 EQASGEQPSGEHASGEQASGAPISSTSTG 185
+ SG +G H Q S S +G
Sbjct: 3353 QSVSGHGQAGPHQQSHQESARDRSGGRSG 3381
Score = 34.3 bits (77), Expect = 0.12
Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 5/109 (4%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
+E S +S H A ++GE S H ++ H+ H G+ S + SG
Sbjct: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGH--GQASSAVRDSGHRGY 2039
Query: 126 GEQPLSELESGEQPSDEQ---PSGEHGSGEQPSGEQASGEQPSGEHASG 171
S+ E + SD Q G+ G +Q E A G+ SG
Sbjct: 2040 SGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSG 2088
Score = 33.9 bits (76), Expect = 0.15
Identities = 29/117 (24%), Positives = 43/117 (36%), Gaps = 5/117 (4%)
Query: 70 SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQP 129
SS ++HT E +S A S H +A E H + S H G+
Sbjct: 1973 SSRQSGTRHT--ESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGH--GQAS 2028
Query: 130 LSELESGEQP-SDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
+ +SG + S Q S G E + S + +G H + S S S+G
Sbjct: 2029 SAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSG 2085
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/142 (21%), Positives = 53/142 (37%), Gaps = 9/142 (6%)
Query: 32 HQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES 91
HQ S Q+ + + LY+ S+ + S HG + + + G H E
Sbjct: 3364 HQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR------QGSHHEQ 3417
Query: 92 EHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL-ESGEQPSDEQPSGEHGS 150
S +A++ EG+ T+ P + + EQ + SG S G +
Sbjct: 3418 ARDSSRHSASQ--EGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA 3475
Query: 151 GEQPSGEQASGEQPSGEHASGE 172
SG +++ Q + SG+
Sbjct: 3476 SRGQSGSRSASRQTRNDEQSGD 3497
Score = 33.5 bits (75), Expect = 0.20
Identities = 34/146 (23%), Positives = 48/146 (32%), Gaps = 27/146 (18%)
Query: 66 SEHGSSEH-------GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQ 118
S H S H GSS+H+ +++ G + + H+ + E
Sbjct: 1554 SRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSES 1613
Query: 119 PSGEHLSGEQPLSELESGEQPSDEQPSGEHG------------SGEQPSGEQASGEQ--- 163
S H + S S S ++ HG E SG QA+ Q
Sbjct: 1614 ASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQA 1673
Query: 164 ---PSGEHASGEQASGAPISSTSTGT 186
P H S Q S SST +GT
Sbjct: 1674 RSSPGERHGSRHQQSAD--SSTDSGT 1697
Score = 33.1 bits (74), Expect = 0.26
Identities = 43/190 (22%), Positives = 60/190 (31%), Gaps = 32/190 (16%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPS-------------DAEALYETSSG 61
SARG S + + SGS +Q S + PS D+ + G
Sbjct: 2723 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDG 2782
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + EH+ SG H + G A+ G +
Sbjct: 2783 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 2842
Query: 116 GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
E+ SG+ S S + H + S QA Q G S Q S
Sbjct: 2843 NEEQSGD-----------GSRHSGSRHHEASTHADISRHS--QAVQGQSEGSRRSRRQGS 2889
Query: 176 GAPISSTSTG 185
S S G
Sbjct: 2890 SVSQDSDSEG 2899
Score = 33.1 bits (74), Expect = 0.26
Identities = 43/190 (22%), Positives = 60/190 (31%), Gaps = 32/190 (16%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPS-------------DAEALYETSSG 61
SARG S + + SGS +Q S + PS D+ + G
Sbjct: 3047 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYG 3106
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + EH+ SG H + G A+ G +
Sbjct: 3107 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 3166
Query: 116 GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
E+ SG+ S S + H + S QA Q G S Q S
Sbjct: 3167 NEEQSGD-----------SSRHSVSRHHEASTHADISRHS--QAVQGQSEGSRRSRRQGS 3213
Query: 176 GAPISSTSTG 185
S S G
Sbjct: 3214 SVSQDSDSEG 3223
Score = 33.1 bits (74), Expect = 0.26
Identities = 34/168 (20%), Positives = 51/168 (30%), Gaps = 9/168 (5%)
Query: 27 SGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSG 86
S S H+ S Q A + G + + S H + S
Sbjct: 3502 SWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 3561
Query: 87 EH---AESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ 143
H A+ + G T H E G + SG H + + S + +
Sbjct: 3562 NHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 3621
Query: 144 PSGEHGSGEQPSGEQA------SGEQPSGEHASGEQASGAPISSTSTG 185
HGS Q S + + G+ S SG + S +S S G
Sbjct: 3622 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEG 3669
Score = 32.7 bits (73), Expect = 0.34
Identities = 35/179 (19%), Positives = 58/179 (32%), Gaps = 21/179 (11%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPS-------------DAEALYETSSG 61
S RG S+ + SGS +Q S + PS D+ + G
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG 3754
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + + E + SG H + G A+ G + +
Sbjct: 3755 QDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETR 3814
Query: 116 GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQA 174
E+ SG+ S +D + G GE ++ + S S +A
Sbjct: 3815 NEEQSGD--GSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA 3871
Score = 32.3 bits (72), Expect = 0.44
Identities = 29/130 (22%), Positives = 45/130 (34%), Gaps = 14/130 (10%)
Query: 70 SSEHGSSKHTV-AEHTSGEHAESEHAS-------GEPAATEHAEGEHTVGEQPSGEQPSG 121
S + S H+ +E SG + + H S G H E + G + SG
Sbjct: 298 SQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSG 357
Query: 122 EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQA------SGEQPSGEHASGEQAS 175
+ + S + + P HGSG Q S + + G+ S G + S
Sbjct: 358 TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGS 417
Query: 176 GAPISSTSTG 185
+S S G
Sbjct: 418 SGSQASDSEG 427
Score = 32.0 bits (71), Expect = 0.57
Identities = 35/130 (26%), Positives = 48/130 (36%), Gaps = 19/130 (14%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSG 116
ETSS T +S H A + GE S H ++ A G G+ S
Sbjct: 362 ETSSRGQT----------ASSHEQARSSPGERHGSGHQQSADSSRHSATGR---GQASSA 408
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQA-- 174
G S S+ E + SD Q HG +G + Q S SGE++
Sbjct: 409 VSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK----AGLRQQSHQESTRGRSGERSGR 464
Query: 175 SGAPISSTST 184
SG+ + ST
Sbjct: 465 SGSSLYQVST 474
Score = 31.6 bits (70), Expect = 0.75
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 15/120 (12%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSG 116
+TSSG +S H A ++GE S H ++ G G+ S
Sbjct: 2632 QTSSGGQ----------AASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSA 2678
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHG-SGEQPSGEQASGEQPSGEHASGEQAS 175
+ SG S+ E + SD Q HG +G Q S SGE SG S
Sbjct: 2679 VRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE-TSGHSGS 2737
Score = 31.6 bits (70), Expect = 0.75
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 15/120 (12%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSG 116
+TSSG +S H A ++GE S H ++ G G+ S
Sbjct: 2956 QTSSGGQ----------AASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSA 3002
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHG-SGEQPSGEQASGEQPSGEHASGEQAS 175
+ SG S+ E + SD Q HG +G Q S SGE SG S
Sbjct: 3003 VRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE-TSGHSGS 3061
Score = 31.2 bits (69), Expect = 0.98
Identities = 48/207 (23%), Positives = 75/207 (36%), Gaps = 41/207 (19%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHG 74
S RG S + + SGS +Q S E P A TS+G S H +
Sbjct: 453 STRGRSGERSGRSGSSLYQVSTH---------EQPDSAHGRTGTSTGGRQGSHHEQARD- 502
Query: 75 SSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELE 134
SS+H+ ++ G+ H + + E +V SG SG H S
Sbjct: 503 SSRHSASQE--GQDTIRGHPGSSRGGRQGSHHEQSVNR--SGH--SGSHHS--------H 548
Query: 135 SGEQPSDEQPSGEHGS---GEQPSGEQASGE----QPSGEHASGEQASGAPISSTSTGTI 187
+ Q + G+ GS Q E+ SG+ S H + QA + S G
Sbjct: 549 TTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQG-- 606
Query: 188 LNCYTCAYMNDQGKCLRGEGTCITQNS 214
+ + R +G+ ++Q+S
Sbjct: 607 --------QSSGPRTSRNQGSSVSQDS 625
Score = 31.2 bits (69), Expect = 0.98
Identities = 41/174 (23%), Positives = 62/174 (35%), Gaps = 19/174 (10%)
Query: 32 HQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES 91
HQ S Q+ + + LY+ S+ + S HG + + + H +
Sbjct: 2392 HQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSR 2451
Query: 92 EHASGEPAATEHAE-GEHTVGEQPSGEQP-------SGEHLS-----GEQPLSELESGEQ 138
S E T H G + G Q S + SG H S G S SG +
Sbjct: 2452 HSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSR 2511
Query: 139 PSDEQPSGEH--GSGEQPSG----EQASGEQPSGEHASGEQASGAPISSTSTGT 186
+ Q + G G + SG E +S SG G+ S P +S + G+
Sbjct: 2512 SASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGS 2565
Score = 30.8 bits (68), Expect = 1.3
Identities = 37/174 (21%), Positives = 59/174 (33%), Gaps = 9/174 (5%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHG 74
SARG S + + SGS +Q S + PS S H +S+ G
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134
Query: 75 SSKHTVAEHTSGEHAESEHASGEPAATEHA-EGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
+ T+ H + + E + G H G + SG + S
Sbjct: 2135 --QDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS-- 2190
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHA-SGEQASGAPISSTSTGT 186
+ D++ SG+ +AS S H+ G+ S P +S G+
Sbjct: 2191 ---RKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGS 2241
Score = 30.8 bits (68), Expect = 1.3
Identities = 30/126 (23%), Positives = 44/126 (34%), Gaps = 9/126 (7%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
++ S +S H A ++GE S H ++ G G+ S + SG
Sbjct: 2631 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSAVRDSGHRGY 2687
Query: 126 GEQPLSELESGEQPSDEQP------SGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPI 179
S+ E + SD Q +G H Q S SGE + Q S
Sbjct: 2688 SGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQ 2747
Query: 180 SSTSTG 185
S +S G
Sbjct: 2748 SESSHG 2753
Score = 30.8 bits (68), Expect = 1.3
Identities = 30/126 (23%), Positives = 44/126 (34%), Gaps = 9/126 (7%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
++ S +S H A ++GE S H ++ G G+ S + SG
Sbjct: 2955 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSAVRDSGHRGY 3011
Query: 126 GEQPLSELESGEQPSDEQP------SGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPI 179
S+ E + SD Q +G H Q S SGE + Q S
Sbjct: 3012 SGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQ 3071
Query: 180 SSTSTG 185
S +S G
Sbjct: 3072 SESSHG 3077
Score = 30.0 bits (66), Expect = 2.2
Identities = 29/121 (23%), Positives = 43/121 (35%), Gaps = 5/121 (4%)
Query: 70 SSEHGS--SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGE--QPSGEQ-PSGEHL 124
SS HG S H A + GE S H ++ G + SG + SG +
Sbjct: 1336 SSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQV 1395
Query: 125 SGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+ + SE + S +G H + S SGE + Q S S ++
Sbjct: 1396 TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTH 1455
Query: 185 G 185
G
Sbjct: 1456 G 1456
Score = 29.6 bits (65), Expect = 2.8
Identities = 35/157 (22%), Positives = 53/157 (33%), Gaps = 6/157 (3%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDA--EALYETSSGLNTLSEHGSSEHGSSKH 78
S P E GS HQ S S A ++ + SSG + G SE ++
Sbjct: 1351 SSPGERHGS-RHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQS 1409
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ 138
A +G H +S S + E + + Q S + S P + G +
Sbjct: 1410 VSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSR 1469
Query: 139 PSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
+ S H + + G+ P G G Q S
Sbjct: 1470 HEQARNSSRHSASQ--DGQDTIRGHP-GSSRGGRQGS 1503
Score = 29.6 bits (65), Expect = 2.8
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 23/174 (13%)
Query: 32 HQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGS-----SKHTVAEHTSG 86
HQ S + GE + LY+ S+ + S HG + + S+H A +S
Sbjct: 1747 HQESTRGQSGE----RSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSR 1802
Query: 87 EHAESEHAS---GEPAATEHA-EGEH-TVGEQPSGEQPSGEHLSGEQPLSELESGE---- 137
A E G P ++ +G H SG S + Q S++ G+
Sbjct: 1803 HSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR 1862
Query: 138 ----QPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS-GEQASGAPISSTSTGT 186
Q +E+ SG+ +AS S H+ G+ S P +S + G+
Sbjct: 1863 SVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGS 1916
Score = 29.3 bits (64), Expect = 3.7
Identities = 30/150 (20%), Positives = 52/150 (34%), Gaps = 23/150 (15%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESE--------HASGEP 98
E S +A ++ E S H S + + +G +S +SG
Sbjct: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ 1718
Query: 99 AATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ-----------PSDEQPSGE 147
A+ E + + S +G H Q + +SGE+ + EQ
Sbjct: 1719 ASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESA 1778
Query: 148 HG-SGEQPSGEQASGEQ---PSGEHASGEQ 173
HG +G G Q S + S H++ ++
Sbjct: 1779 HGRTGPSTGGRQRSRHEQARDSSRHSASQE 1808
Score = 28.5 bits (62), Expect = 6.3
Identities = 32/134 (23%), Positives = 47/134 (35%), Gaps = 22/134 (16%)
Query: 71 SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS------------GEQ 118
S H S+H A + S+ GE A + + + + Q S E
Sbjct: 3823 SRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSES 3882
Query: 119 PSGEHLSGEQPLSELESGEQPSDEQPSGEH---------GSGEQPSGEQASGEQPSGEHA 169
S H + S S S + + H S + G +S Q S H
Sbjct: 3883 ASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYH- 3941
Query: 170 SGEQASGAPISSTS 183
SG Q+ G+P SS+S
Sbjct: 3942 SGIQSRGSPHSSSS 3955
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 41.2 bits (95), Expect = 0.001
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 8/97 (8%)
Query: 83 HTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDE 142
H +G S +P T H E G SG PS L+ P S+ E S
Sbjct: 853 HPTGSRLADPRLSRDPRLTRHVEASGGSGPGDSG--PSDPRLARALPTSKPEGSLHSSPV 910
Query: 143 QPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPI 179
PS GSG P+ E+ GE A E+A P+
Sbjct: 911 GPSSSKGSGPPPT------EEEEGERALREKAVNIPL 941
>gi|49087132 sal-like 2 [Homo sapiens]
Length = 1007
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 11/163 (6%)
Query: 14 GSARGTSSQPNELSG--SIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSS 71
G+A+ S+ + +SG S Q S Q P E S E + E E + ++L+ GS
Sbjct: 730 GAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSE 789
Query: 72 EHGSSKHTV---AEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE 127
G +V +E SG E A+ A E E T + P + L
Sbjct: 790 SGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQP 849
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHAS 170
QP+ + SG E+ G + S AS P GE S
Sbjct: 850 QPMEQGSSGVLGGKEE-----GGKPERSSSPASALTPEGEATS 887
Score = 37.7 bits (86), Expect = 0.010
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 96 GEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEH----GSG 151
G AA E+ + TV S Q + S E+ LSE E E +E+ + G G
Sbjct: 728 GGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRG 787
Query: 152 EQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
+ GE+A + E ASG + +++ +T
Sbjct: 788 SESGGEKAISVRGDSEEASGAEEEVGTVAAAAT 820
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 112 EQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASG 171
+QP +P + +P + +PS +QP +QP + S +QPS S
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 172 EQASGAPISSTSTG 185
+Q S P+S T +G
Sbjct: 552 QQ-STKPVSQTGSG 564
Score = 32.0 bits (71), Expect = 0.57
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Query: 113 QPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEH--------GSGE--QPSGEQASGE 162
+PS +QP +QP S S +QPS +PS + GSG+ QP S +
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577
Query: 163 QPSGE 167
QP +
Sbjct: 578 QPPSQ 582
Score = 30.0 bits (66), Expect = 2.2
Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 6/95 (6%)
Query: 81 AEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPS 140
A+ T E SE + A G+ T +QP +P + + +PL+ +QP
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLA-----QQPG 426
Query: 141 DEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
+ P+ G + P + G+ P+ + G+ ++
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Score = 28.1 bits (61), Expect = 8.3
Identities = 22/102 (21%), Positives = 37/102 (36%), Gaps = 13/102 (12%)
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLS-----GEQPLSELESGEQPSDE--------Q 143
+P + T E+PS EQP + L+ G+ P + + P+ + Q
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 144 PSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
G + P + +QP +QA S+ TG
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 112 EQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASG 171
+QP +P + +P + +PS +QP +QP + S +QPS S
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 172 EQASGAPISSTSTG 185
+Q S P+S T +G
Sbjct: 552 QQ-STKPVSQTGSG 564
Score = 32.0 bits (71), Expect = 0.57
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Query: 113 QPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEH--------GSGE--QPSGEQASGE 162
+PS +QP +QP S S +QPS +PS + GSG+ QP S +
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577
Query: 163 QPSGE 167
QP +
Sbjct: 578 QPPSQ 582
Score = 30.0 bits (66), Expect = 2.2
Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 6/95 (6%)
Query: 81 AEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPS 140
A+ T E SE + A G+ T +QP +P + + +PL+ +QP
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLA-----QQPG 426
Query: 141 DEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQAS 175
+ P+ G + P + G+ P+ + G+ ++
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Score = 28.1 bits (61), Expect = 8.3
Identities = 22/102 (21%), Positives = 37/102 (36%), Gaps = 13/102 (12%)
Query: 97 EPAATEHAEGEHTVGEQPSGEQPSGEHLS-----GEQPLSELESGEQPSDE--------Q 143
+P + T E+PS EQP + L+ G+ P + + P+ + Q
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 144 PSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTG 185
G + P + +QP +QA S+ TG
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 40.4 bits (93), Expect = 0.002
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 3/115 (2%)
Query: 70 SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQP 129
S E SS +T E +ESE E + +E E + P E+ GE+
Sbjct: 1603 SEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEES--STPESEESESTESEGEKA 1660
Query: 130 LSELE-SGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTS 183
+ + +P E+ G E+P EQ + EH+ E++ AP+ ++
Sbjct: 1661 RKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEHSEEEESGPAPVEEST 1715
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/182 (23%), Positives = 61/182 (33%), Gaps = 13/182 (7%)
Query: 9 SLYLLGS---ARGTSSQPNELSGSIDHQTSVQQLPG-EFFSLENPSDAEALYETSSGLNT 64
SL LGS A G+S + D + + PG F NP + G
Sbjct: 2497 SLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEE 2556
Query: 65 LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHL 124
SS GSS + + +SG E GE ++ +G G G S
Sbjct: 2557 SESSSSSSSGSSSSSSSSSSSGSETE-----GEEEGDKNGDG----GCGTGGRNCSAASS 2607
Query: 125 SGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTST 184
P S S S S S S +S S +S +S + SS+S+
Sbjct: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667
Query: 185 GT 186
+
Sbjct: 2668 SS 2669
Score = 29.3 bits (64), Expect = 3.7
Identities = 30/150 (20%), Positives = 48/150 (32%), Gaps = 10/150 (6%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSS--------EHGSSKHTVAEHTSGEHAESEHASGEP 98
+ ++E+ +SSG ++ S SS E G T G + + AS
Sbjct: 2552 DGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSA--ASSRA 2609
Query: 99 AATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQ 158
A+ + + S S S S S S S S S
Sbjct: 2610 ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669
Query: 159 ASGEQPSGEHASGEQASGAPISSTSTGTIL 188
+S +S ++A+ AP + S L
Sbjct: 2670 SSTTDEDSSCSSDDEAAPAPTAGPSAQAAL 2699
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,835,542
Number of Sequences: 37866
Number of extensions: 662045
Number of successful extensions: 5541
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 335
Number of HSP's that attempted gapping in prelim test: 3676
Number of HSP's gapped (non-prelim): 1452
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.