Search of human proteins with 44917606

Search of human proteins with 44917606

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44917606 N-ethylmaleimide-sensitive factor attachment
protein, beta [Homo sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44917606 N-ethylmaleimide-sensitive factor attachment protein...   594   e-170
gi|47933379 N-ethylmaleimide-sensitive factor attachment protein...   506   e-143
gi|4505331 N-ethylmaleimide-sensitive factor attachment protein,...    64   2e-10
gi|55743151 WD repeat domain 19 [Homo sapiens]                         38   0.009
gi|116534937 interferon-induced protein with tetratricopeptide r...    35   0.061
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    32   0.68 
gi|46358428 selective LIM binding factor homolog [Homo sapiens]        32   0.88 
gi|91823262 annexin A8 [Homo sapiens]                                  31   1.2  
gi|149588958 annexin A8-like 1 [Homo sapiens]                          31   1.2  
gi|145386551 SH3 domain and tetratricopeptide repeats 1 [Homo sa...    30   2.0  
gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]          30   2.0  
gi|148806872 lupus brain antigen 1 [Homo sapiens]                      30   3.4  
gi|4506803 stem cell growth factor precursor [Homo sapiens]            29   4.4  
gi|126032338 ryanodine receptor 3 [Homo sapiens]                       29   4.4  
gi|83415184 transmembrane and tetratricopeptide repeat containin...    29   4.4  
gi|5174675 cysteine-rich secretory protein 3 [Homo sapiens]            29   5.7  
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            28   7.5  
gi|90193622 integrator complex subunit 6 isoform b [Homo sapiens]      28   7.5  
gi|11024694 integrator complex subunit 6 isoform a [Homo sapiens]      28   7.5  
gi|30520339 hypothetical protein LOC154313 isoform 2 [Homo sapiens]    28   7.5  
gi|72534780 hypothetical protein LOC154313 isoform 1 [Homo sapiens]    28   7.5  
gi|122937345 myosin VB [Homo sapiens]                                  28   9.8  

>gi|44917606 N-ethylmaleimide-sensitive factor attachment protein,
           beta [Homo sapiens]
          Length = 298

 Score =  594 bits (1532), Expect = e-170
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSA 60
           MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSA
Sbjct: 1   MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSA 60

Query: 61  AGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIA 120
           AGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIA
Sbjct: 61  AGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIA 120

Query: 121 AKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQK 180
           AKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQK
Sbjct: 121 AKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQK 180

Query: 181 AIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRE 240
           AIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRE
Sbjct: 181 AIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRE 240

Query: 241 CKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK 298
           CKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK
Sbjct: 241 CKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK 298


>gi|47933379 N-ethylmaleimide-sensitive factor attachment protein,
           alpha [Homo sapiens]
          Length = 295

 Score =  506 bits (1302), Expect = e-143
 Identities = 246/292 (84%), Positives = 274/292 (93%)

Query: 1   MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSA 60
           MDN+GKE EA+ L+AEAE++VK S SF  GLFGG+++IEEACE+Y RAANMFKMAKNWSA
Sbjct: 1   MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSA 60

Query: 61  AGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIA 120
           AGNAFCQAA+LH+QLQSKHD+AT FVDAGNA+KKADPQEAINCL  AI+IYTDMGRFTIA
Sbjct: 61  AGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIA 120

Query: 121 AKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQK 180
           AKHHI+IAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVA YAA LEQYQK
Sbjct: 121 AKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQK 180

Query: 181 AIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRE 240
           AI+IYEQVG N MD+PLLKYSAKDYFFKAALCHF +D LNAKLA++KYEE+FPAF+DSRE
Sbjct: 181 AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRE 240

Query: 241 CKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGE 292
           CKL+KKLLEAHEEQN ++YTE+VKE+DSISRLDQWLTTMLLRIKK+IQGD E
Sbjct: 241 CKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEE 292


>gi|4505331 N-ethylmaleimide-sensitive factor attachment protein,
           gamma [Homo sapiens]
          Length = 312

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 71/272 (26%), Positives = 114/272 (41%), Gaps = 36/272 (13%)

Query: 4   AGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGN 63
           A K  E ++ +A+AEK +K       G        + A   Y +AA  FK AK +  A +
Sbjct: 3   AQKINEGLEHLAKAEKYLKT------GFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKD 56

Query: 64  AFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADP-QEAINCLNAAIDIYTDMGRFTIAAK 122
           A  + A  H   ++   +A ++  AG   K+     EA+  +  A  +Y + G    AA 
Sbjct: 57  ACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAM 116

Query: 123 HHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKV------------AA 170
                 ++ E   VD EKA+  Y+Q+A+ ++ EE    A + L K             AA
Sbjct: 117 ALERAGKLIEN--VDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAA 174

Query: 171 YAAQLEQ-YQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYE 229
            + Q E+   K IE Y      T+   L+     DY   A  C             E Y 
Sbjct: 175 LSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDY-VAAERC-----------VRESYS 222

Query: 230 EMFPAFTDSRECKLLKKLLEAHEEQNSEAYTE 261
              P F  S +C  L++LLE +++Q+ +  ++
Sbjct: 223 --IPGFNGSEDCAALEQLLEGYDQQDQDQVSD 252


>gi|55743151 WD repeat domain 19 [Homo sapiens]
          Length = 1342

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 53/262 (20%), Positives = 99/262 (37%), Gaps = 49/262 (18%)

Query: 45   YTRAANMFKMAKNWSAAGNAF--CQAAKLHMQLQSKHDSATSFVDAGNAYKKA------- 95
            Y +AA+++  +KNW+  G+      + K+H+Q     ++   + +A  AY+ A       
Sbjct: 869  YDKAASVYIRSKNWAKVGDLLPHVSSPKIHLQYAKAKEADGRYKEAVVAYENAKQWQSVI 928

Query: 96   --------DPQEAINCLNAAIDI---------YTDMG-----------------RFTIAA 121
                    +P++A+N +     +         +  +G                  FT+A 
Sbjct: 929  RIYLDHLNNPEKAVNIVRETQSLDGAKMVARFFLQLGDYGSAIQFLVMSKCNNEAFTLAQ 988

Query: 122  KHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKA 181
            +H+    EIY   +   +     Y+  A Y++GE+    A K  L    Y+  L+ + K 
Sbjct: 989  QHN--KMEIYADIIGSEDTTNEDYQSIALYFEGEKRYLQAGKFFLLCGQYSRALKHFLKC 1046

Query: 182  IEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKY-EEMFPAFTDSRE 240
                + V        +    AKD      L   ++ E +      KY   ++ A    RE
Sbjct: 1047 PSSEDNVAIEMAIETV--GQAKDELLTNQLIDHLLGENDGMPKDAKYLFRLYMALKQYRE 1104

Query: 241  CKLLKKLLEAHEEQNSEAYTEA 262
                  ++ A EEQ++  Y  A
Sbjct: 1105 A-AQTAIIIAREEQSAGNYRNA 1125


>gi|116534937 interferon-induced protein with tetratricopeptide
           repeats 1 isoform 2 [Homo sapiens]
          Length = 478

 Score = 35.4 bits (80), Expect = 0.061
 Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 11/162 (6%)

Query: 37  RIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKH-DSATSFVDAGNAYKKA 95
           +I+EA +   R  N  K+ K   +A   F  A +     +  H D A  +++AGN  K  
Sbjct: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360

Query: 96  DPQEAINCLNAAI-----DIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSAD 150
           +  + + C+   +     DI+   GRF    K     A I+  + + IE+A    ++S +
Sbjct: 361 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 420

Query: 151 YYKGEESNSSANKCL----LKVAAYAAQLE-QYQKAIEIYEQ 187
             K         K L    L +  +  +LE    +A+E YE+
Sbjct: 421 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYER 462


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 32.0 bits (71), Expect = 0.68
 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 21/101 (20%)

Query: 132  ETELVDIEKAIAHYEQSADYYKGEESNSSANKCLL-----KVAAYAAQLEQYQKAIEIYE 186
            + EL   E+A  H EQ  D    E +NS++ K  L     ++ A  AQLE+     E+ E
Sbjct: 1693 QEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEE-----ELEE 1747

Query: 187  QVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEK 227
            +     + N        D F K  L    VD LNA+LA E+
Sbjct: 1748 EQSNMELLN--------DRFRKTTL---QVDTLNAELAAER 1777


>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
          Length = 1749

 Score = 31.6 bits (70), Expect = 0.88
 Identities = 40/159 (25%), Positives = 63/159 (39%), Gaps = 32/159 (20%)

Query: 43  EMYTRAANMFKMAKNWSAA------GNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKAD 96
           E+Y RA ++F+   N   A      GNAF +A +L                     + A 
Sbjct: 810 ELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELA--------------------RLAF 849

Query: 97  PQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAI-AHYEQSADYYKGE 155
           P E +    A  D      +   A  H+I         +  IE A+ A   + A Y    
Sbjct: 850 PVEVVKLEEAWGDHLVQQKQLDAAINHYIEA----RCSIKAIEAALGARQWKKAIYILDL 905

Query: 156 ESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMD 194
           +  ++A+K    VA + A L++Y+ A E+Y + G  T D
Sbjct: 906 QDRNTASKYYPLVAQHYASLQEYEIAEELYTK-GDRTKD 943


>gi|91823262 annexin A8 [Homo sapiens]
          Length = 327

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 41/148 (27%), Positives = 58/148 (39%), Gaps = 23/148 (15%)

Query: 75  LQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIY-TDMGRF-----TIAAKHHITIA 128
           LQ   D  +SFVD G A      Q+A +   A   I  TD  +F     T +A H + + 
Sbjct: 163 LQGSRDDVSSFVDPGLAL-----QDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVF 217

Query: 129 EIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQV 188
           E YE         IA+  +S +     E++ S  + +L V      L  Y      Y   
Sbjct: 218 EEYE--------KIAN--KSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMK 267

Query: 189 GANTMDNPLLK--YSAKDYFFKAALCHF 214
           GA T D  L++   S  +       CHF
Sbjct: 268 GAGTRDGTLIRNIVSRSEIDLNLIKCHF 295


>gi|149588958 annexin A8-like 1 [Homo sapiens]
          Length = 327

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 41/148 (27%), Positives = 58/148 (39%), Gaps = 23/148 (15%)

Query: 75  LQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIY-TDMGRF-----TIAAKHHITIA 128
           LQ   D  +SFVD G A      Q+A +   A   I  TD  +F     T +A H + + 
Sbjct: 163 LQGSRDDVSSFVDPGLAL-----QDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVF 217

Query: 129 EIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQV 188
           E YE         IA+  +S +     E++ S  + +L V      L  Y      Y   
Sbjct: 218 EEYE--------KIAN--KSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMK 267

Query: 189 GANTMDNPLLK--YSAKDYFFKAALCHF 214
           GA T D  L++   S  +       CHF
Sbjct: 268 GAGTRDGTLIRNIVSRSEIDLNLIKCHF 295


>gi|145386551 SH3 domain and tetratricopeptide repeats 1 [Homo
            sapiens]
          Length = 1336

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 16/60 (26%), Positives = 28/60 (46%)

Query: 92   YKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADY 151
            Y   DP +A      A+    D+G      K +  +A IY   L+D EK++  Y+++  +
Sbjct: 1248 YDLKDPFDAAGYYQLALAAAVDLGNKKAQLKIYTRLATIYHNFLLDREKSLFFYQKARTF 1307


>gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]
          Length = 766

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 9/89 (10%)

Query: 204 DYFFKAALCHFIVDE----LNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAY 259
           D F  + +C  +V+E    +NA    E +E  F  F+D R  +L +  +   E+   +  
Sbjct: 39  DIFLPSEICDRLVNEYVELVNAACNFEPHESFFSLFSDPRSTRLTR--IHLREDLVQDQD 96

Query: 260 TEAVKEFDSISRLDQWLTTMLLRIKKSIQ 288
            EA+++ D +   + +LT       KS+Q
Sbjct: 97  LEAIRKQDLV---ELYLTNCEKLSAKSLQ 122


>gi|148806872 lupus brain antigen 1 [Homo sapiens]
          Length = 2375

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 51/216 (23%), Positives = 86/216 (39%), Gaps = 37/216 (17%)

Query: 78   KHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIA--AKHHITIAEIYETEL 135
            K  +   ++  G+ Y K        C   A   Y   G F     A  H T   +   ++
Sbjct: 1145 KTSTPAEWIAQGDYYAKHQ------CWKVAAKCYQKGGAFEKEKLALAHDTALSMKSKKV 1198

Query: 136  VDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDN 195
               EK + + E +  Y + +E   S     LK  +YA   +++Q + ++ E++G      
Sbjct: 1199 SPKEKQLEYLELAKTYLECKEPTLS-----LKCLSYA---KEFQLSAQLCERLGKIRDAA 1250

Query: 196  PLLKYSA--KDYF--------FKAALCHFIVDEL--NAKLALEKYEEMFPAFTDSRECKL 243
               K S   KD F        F  AL  +  +EL   A +A+EKYEEM    T       
Sbjct: 1251 YFYKRSQCYKDAFRCFEQIQEFDLALKMYCQEELFEEAAIAVEKYEEMLKTKT-----LP 1305

Query: 244  LKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTM 279
            + KL        S+ Y EA  ++ S +++ + +  +
Sbjct: 1306 ISKL----SYSASQFYLEAAAKYLSANKMKEMMAVL 1337


>gi|4506803 stem cell growth factor precursor [Homo sapiens]
          Length = 323

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 1/44 (2%)

Query: 4   AGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTR 47
           AG  R+AVQ + EA+ R +  H  L G   G  R+   C + +R
Sbjct: 150 AGDTRDAVQALQEAQGRAEREHGRLEGCLKG-LRLGHKCFLLSR 192


>gi|126032338 ryanodine receptor 3 [Homo sapiens]
          Length = 4870

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 8/85 (9%)

Query: 146  EQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDY 205
            E+ A+Y   E +     +C  KV    A    + K +EIY+          LL Y A+++
Sbjct: 4359 EEQAEYLWTEVTKKKKRRCGQKVEKPEAFTANFFKGLEIYQ--------TKLLHYLARNF 4410

Query: 206  FFKAALCHFIVDELNAKLALEKYEE 230
            +    L  F+   +N  L   K  E
Sbjct: 4411 YNLRFLALFVAFAINFILLFYKVTE 4435


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 65/209 (31%)

Query: 41  ACEMYTRAA----NMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKAD 96
           A ++Y R A    N+  + ++ + A   + +A +LH Q    H+ A    + GN  K  +
Sbjct: 401 ALKLYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQ----HNRA--LFNLGNLLKSQE 454

Query: 97  P-QEAINCLNAAI-------DIYTDMGRFTIAAKHHITIAEIYETE-------------- 134
             +EAI  L  +I       D Y+ +       +      EIY+T               
Sbjct: 455 KKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNY 514

Query: 135 ---LVDI---EKAIAHYEQS--------------ADYYKGEESNSSAN---KCLLKVAAY 171
              LVD    EKA+AHY+Q+                 Y+    NS A    K  L+VA  
Sbjct: 515 GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK 574

Query: 172 AAQLE----------QYQKAIEIYEQVGA 190
           A  L           +Y++A++IY++  A
Sbjct: 575 AEILSPLGALYYNTGRYEEALQIYQEAAA 603


>gi|5174675 cysteine-rich secretory protein 3 [Homo sapiens]
          Length = 245

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 28/110 (25%), Positives = 39/110 (35%), Gaps = 5/110 (4%)

Query: 48  AANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAA 107
           A NM KM  N  AA NA   A + + +  +  D  TS     N Y  +        + + 
Sbjct: 57  ARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSW 116

Query: 108 IDIYTDMG-----RFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYY 152
            D Y D       +   A   H T    Y + LV    A    ++   YY
Sbjct: 117 FDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYY 166


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 19/94 (20%), Positives = 41/94 (43%)

Query: 132  ETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGAN 191
            + +L D+EK      +  ++ +G E     +  L    +   QL+  Q+A++   QV  N
Sbjct: 2499 QEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLN 2558

Query: 192  TMDNPLLKYSAKDYFFKAALCHFIVDELNAKLAL 225
              +  +  Y A     +A     ++ E++ ++ L
Sbjct: 2559 EFEQWITHYQAAFNNLEATQLASLLQEISTQMDL 2592


>gi|90193622 integrator complex subunit 6 isoform b [Homo sapiens]
          Length = 874

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 229 EEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQ 288
           EE  PA + ++  KL+     +HEE N+E   + +KE     R  + + T+L  ++ S+Q
Sbjct: 772 EENIPASSLNKGKKLMH--CRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQ 829


>gi|11024694 integrator complex subunit 6 isoform a [Homo sapiens]
          Length = 887

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 229 EEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQ 288
           EE  PA + ++  KL+     +HEE N+E   + +KE     R  + + T+L  ++ S+Q
Sbjct: 785 EENIPASSLNKGKKLMH--CRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQ 842


>gi|30520339 hypothetical protein LOC154313 isoform 2 [Homo sapiens]
          Length = 505

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 6/81 (7%)

Query: 174 QLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFP 233
           QLE  +  +  Y  +     ++PL++   + Y  K AL +    E+  ++ L        
Sbjct: 229 QLETARSQVYRYTAILEKAANDPLMRAELQPYMLKEALYNIRQYEVFLQIILS------D 282

Query: 234 AFTDSRECKLLKKLLEAHEEQ 254
             T ++E +++ K L AH EQ
Sbjct: 283 IITGAQEVEMMTKQLGAHLEQ 303


>gi|72534780 hypothetical protein LOC154313 isoform 1 [Homo sapiens]
          Length = 622

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 6/81 (7%)

Query: 174 QLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFP 233
           QLE  +  +  Y  +     ++PL++   + Y  K AL +    E+  ++ L        
Sbjct: 229 QLETARSQVYRYTAILEKAANDPLMRAELQPYMLKEALYNIRQYEVFLQIILS------D 282

Query: 234 AFTDSRECKLLKKLLEAHEEQ 254
             T ++E +++ K L AH EQ
Sbjct: 283 IITGAQEVEMMTKQLGAHLEQ 303


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 16/141 (11%)

Query: 131  YETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGA 190
            Y  E+  ++K + HY+QS     GE+++    +   +V +   +L++     +I E   A
Sbjct: 955  YTMEVERLKKELVHYQQS----PGEDTSLRLQE---EVESLRTELQRAHSERKILED--A 1005

Query: 191  NTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEA 250
            ++ +   L+    D   + AL     ++LN ++  +  +E      +S +  L+KK L  
Sbjct: 1006 HSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEF---AQNSVKENLMKKEL-- 1060

Query: 251  HEEQNSEAYTEAVKEFDSISR 271
              E+    Y   VKE+  + +
Sbjct: 1061 --EEERSRYQNLVKEYSQLEQ 1079


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,646,915
Number of Sequences: 37866
Number of extensions: 361525
Number of successful extensions: 1132
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1121
Number of HSP's gapped (non-prelim): 25
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.