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Search of human proteins with 42740901
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
(775 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 1571 0.0
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 1571 0.0
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 1571 0.0
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 1459 0.0
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 1303 0.0
gi|56847634 hypothetical protein LOC441294 [Homo sapiens] 1248 0.0
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 1246 0.0
gi|146262005 CTAGE family, member 6 [Homo sapiens] 1244 0.0
gi|193290160 CTAGE family, member 4 [Homo sapiens] 1241 0.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 265 9e-71
gi|118498356 kinectin 1 isoform a [Homo sapiens] 99 2e-20
gi|118498368 kinectin 1 isoform c [Homo sapiens] 99 2e-20
gi|33620775 kinectin 1 isoform a [Homo sapiens] 99 2e-20
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 85 2e-16
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 85 2e-16
gi|156104908 myosin heavy chain 6 [Homo sapiens] 84 4e-16
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 82 2e-15
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 81 4e-15
gi|55770834 centromere protein F [Homo sapiens] 81 4e-15
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 80 6e-15
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 80 6e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 9e-15
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 80 9e-15
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 80 9e-15
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 79 1e-14
gi|32698688 citron [Homo sapiens] 79 1e-14
gi|148746195 trichohyalin [Homo sapiens] 79 2e-14
gi|42794779 myosin 18A isoform b [Homo sapiens] 79 2e-14
gi|28416946 myosin 18A isoform a [Homo sapiens] 79 2e-14
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 78 3e-14
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 1571 bits (4069), Expect = 0.0
Identities = 775/775 (100%), Positives = 775/775 (100%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK
Sbjct: 30 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 89
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE
Sbjct: 90 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 149
Query: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK
Sbjct: 150 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 209
Query: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE
Sbjct: 210 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 269
Query: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 270 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 329
Query: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY
Sbjct: 330 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 389
Query: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY
Sbjct: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN
Sbjct: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
Query: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ
Sbjct: 510 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 569
Query: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS
Sbjct: 570 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 629
Query: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP
Sbjct: 630 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 689
Query: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA
Sbjct: 690 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 749
Query: 721 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 775
MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
Sbjct: 750 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 804
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 1571 bits (4069), Expect = 0.0
Identities = 775/775 (100%), Positives = 775/775 (100%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK
Sbjct: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE
Sbjct: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
Query: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK
Sbjct: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
Query: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE
Sbjct: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
Query: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
Query: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY
Sbjct: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
Query: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY
Sbjct: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN
Sbjct: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
Query: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ
Sbjct: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
Query: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS
Sbjct: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
Query: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP
Sbjct: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
Query: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA
Sbjct: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
Query: 721 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 775
MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
Sbjct: 721 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 775
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 1571 bits (4069), Expect = 0.0
Identities = 775/775 (100%), Positives = 775/775 (100%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK
Sbjct: 18 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 77
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE
Sbjct: 78 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 137
Query: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK
Sbjct: 138 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 197
Query: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE
Sbjct: 198 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 257
Query: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 258 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 317
Query: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY
Sbjct: 318 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 377
Query: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY
Sbjct: 378 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 437
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN
Sbjct: 438 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 497
Query: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ
Sbjct: 498 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 557
Query: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS
Sbjct: 558 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 617
Query: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP
Sbjct: 618 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 677
Query: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA
Sbjct: 678 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 737
Query: 721 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 775
MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
Sbjct: 738 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 792
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 1459 bits (3778), Expect = 0.0
Identities = 732/775 (94%), Positives = 732/775 (94%), Gaps = 43/775 (5%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK
Sbjct: 30 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 89
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE
Sbjct: 90 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 149
Query: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK
Sbjct: 150 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 209
Query: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE
Sbjct: 210 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 269
Query: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 270 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 329
Query: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY
Sbjct: 330 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 389
Query: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY
Sbjct: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN
Sbjct: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
Query: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
TAFG RGSRGPGNPLDHQ
Sbjct: 510 TAFG-------------------------------------------RGSRGPGNPLDHQ 526
Query: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS
Sbjct: 527 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 586
Query: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP
Sbjct: 587 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 646
Query: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA
Sbjct: 647 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 706
Query: 721 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 775
MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
Sbjct: 707 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 761
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 1303 bits (3373), Expect = 0.0
Identities = 660/745 (88%), Positives = 682/745 (91%), Gaps = 2/745 (0%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPDS+ YGFPWELVI AAV GFFAVLF LWRSFRSV SRLYV REKK A+ LSGLIEEK
Sbjct: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
KLLEKFSLVQKEYEGYEVESSLK+ASFEKEATEAQSLEATCEKLNR NSEL EILCLE
Sbjct: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLE 119
Query: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
KELKEEKSKHSEQ+ELMADISKRIQSLEDESKSLKSQVAEAKMTFK FQ NEERL+I I+
Sbjct: 120 KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQ 179
Query: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
DA ENS+LQESQKQLLQEAEVWKEQVSEL KQK TFEDSKVHAEQVLNDKE+HIKTLTE
Sbjct: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
Query: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
RLLKMKD AML ED+TDDDNLELEMNSESE+GAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTL 299
Query: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE+ENQKLQQKLKVMTELY
Sbjct: 300 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
Query: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
QENEMKL+RKL VEE RLEKEEKLSKVDE ISHATEELETYRKRAKDL +E E+TIH Y
Sbjct: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFY 418
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
Q +II HEKKAHDNW AA AERNLNDLRKENAHNRQKLTE E K +LLEKDPY LDVPN
Sbjct: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPN 478
Query: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
TAFGR+HSPYGPSPLGWPSSETRA L PPTLLEGPLRLSPLLP GGGRGSRGPGNP DHQ
Sbjct: 479 TAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQ 538
Query: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
IT ERGESSCDRLTDPHRAPSD G L+PPW+QD RMMFPPPGQSYPDSALPPQRQDRF S
Sbjct: 539 ITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYS 598
Query: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
N RLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKD+LGNL VPDSSLPAENEATGP
Sbjct: 599 NCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGP 658
Query: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
GFVPPPLAPIRG LFPVD RGPF+RRGPPFPPPPPG +FGAS DYF P D PGPP APFA
Sbjct: 659 GFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFA 718
Query: 721 MRNVYPPRGFPPYLPPRPGFFPPPP 745
MRNVY PRGF PY PPRP FFPP P
Sbjct: 719 MRNVYLPRGFLPYRPPRPAFFPPAP 743
>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
Length = 777
Score = 1248 bits (3230), Expect = 0.0
Identities = 625/746 (83%), Positives = 672/746 (90%), Gaps = 2/746 (0%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSELEDEILCL 119
KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKLNRSNSELEDEILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
EK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+EER IAI
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 180 KDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTL 238
KDALNENSQLQ S KQL Q EAEVWK QVSELNKQK+TFEDSKVHAEQVLNDKE+HIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 239 TERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK 298
T L MKD AA+L ED TDDDNLELE+NS+ ENGA LD+P KGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
Query: 299 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE 358
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FE+ENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
Query: 359 LYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIH 418
YQENEMKL+RKLTVEENYR+E+EEKLS+V+EK+S ATE+LETYRK AKDLEEELERT+H
Sbjct: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKLSRATEQLETYRKLAKDLEEELERTVH 449
Query: 419 SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDV 478
YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTETELKFELLEKDP ALDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
Query: 479 PNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLD 538
NTAFGREH+P GP+PLG SSETRAFLSP TLLE PL LSP+LP GGGRG RGPGNPLD
Sbjct: 510 SNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLD 569
Query: 539 HQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRF 598
HQITNERGE SCDRLTDPHRAPSDTGSLS P +QD +MMFPPPGQSYPDSALPPQR+DRF
Sbjct: 570 HQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSALPPQREDRF 629
Query: 599 CSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEAT 658
SNS RLSG AE RSF M SLDKMDGSMPSEMESSRND KDDLGNLNVPDSSLPAENEAT
Sbjct: 630 YSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 659 GPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAP 718
GPGF+PPPLAP+RGPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP DFPGPP AP
Sbjct: 690 GPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 719 FAMRNVYPPRGFPPYLPPRPGFFPPP 744
FAMRN+YPPRG PPY PRPGF+P P
Sbjct: 750 FAMRNIYPPRGLPPYFHPRPGFYPNP 775
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 1246 bits (3225), Expect = 0.0
Identities = 626/746 (83%), Positives = 669/746 (89%), Gaps = 2/746 (0%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSELEDEILCL 119
KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKL+RSNSELEDEILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCL 149
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
EK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+EER IAI
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 180 KDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTL 238
KDALNENSQLQ S KQL Q EAEVWK QVSELNKQK+TFEDSKVHAEQVLNDKE+HIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 239 TERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK 298
T L MKD AA+L ED TDDDNLEL++NS+ ENGA LD+PPKGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLK 329
Query: 299 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE 358
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FE+ENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
Query: 359 LYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIH 418
YQENEMKL+RKLTVEENYR+E+EEKLS+V+EKISHATEELETYRK AKDLEEELERT+H
Sbjct: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVH 449
Query: 419 SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDV 478
YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTE ELKFELLEKDP ALDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDV 509
Query: 479 PNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLD 538
NTAFGREHSP PSPLG PSSETRAF SP TLLE PLRLSP+LPGGGGRG PGNPLD
Sbjct: 510 SNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLD 569
Query: 539 HQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRF 598
HQITNERGE S DRL DPHRAPSDTGSLS P +QDRRMMFPPPGQSYPDS LPPQR+DRF
Sbjct: 570 HQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTLPPQREDRF 629
Query: 599 CSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEAT 658
SNS RLSGPAE RSF M SLDKMD SMPSEMESSRND KDDLGNLNVPDSSLPAENEAT
Sbjct: 630 YSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 659 GPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAP 718
GPG +PPPLAPI GPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP DFPGPP AP
Sbjct: 690 GPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 719 FAMRNVYPPRGFPPYLPPRPGFFPPP 744
FAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 750 FAMRNIYPPRGLPPYLHPRPGFYPNP 775
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 1244 bits (3220), Expect = 0.0
Identities = 623/746 (83%), Positives = 671/746 (89%), Gaps = 2/746 (0%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSELEDEILCL 119
KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKLNRSNSELEDEILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
EK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+EER IAI
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 180 KDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTL 238
KDALNENSQLQ S KQL Q EAEVWK +VSELNKQK+TFEDSKVHAEQVLNDKE+HIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 239 TERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK 298
T L MKD AA+L ED TDDDNLELE+NS+ ENGA LD+P KGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
Query: 299 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE 358
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+Q SLQSEN +FE+ENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTE 389
Query: 359 LYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIH 418
YQE+EMKL+RKLTVEENYR+E+EEKLSKV+EK+S ATE+LETYRK AKDLEEELERT+H
Sbjct: 390 FYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVH 449
Query: 419 SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDV 478
YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTETELKFELLEKDP ALDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
Query: 479 PNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLD 538
NTAFGREH+P GP+PLG SSETRAFLSP TLLE PL LSP+LP GGGRG RGPGNPLD
Sbjct: 510 SNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLD 569
Query: 539 HQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRF 598
HQITNERGE SCDRLTDPHRAPSDTGSLS P +QD +MMFPPPGQSYPDSALPPQR+DRF
Sbjct: 570 HQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSALPPQREDRF 629
Query: 599 CSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEAT 658
SNS RLSG AE RSF M SLDKMDGSMPSEMESSRND KDDLGNLNVPDSSLPAENEAT
Sbjct: 630 YSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 659 GPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAP 718
GPGF+PPPLAP+RGPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP DFPGPP AP
Sbjct: 690 GPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 719 FAMRNVYPPRGFPPYLPPRPGFFPPP 744
FAMRN+YPPRG PPY PRPGF+P P
Sbjct: 750 FAMRNIYPPRGLPPYFHPRPGFYPNP 775
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 1241 bits (3212), Expect = 0.0
Identities = 625/746 (83%), Positives = 667/746 (89%), Gaps = 2/746 (0%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSELEDEILCL 119
KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKLNRSNSELEDEILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
EK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+EER IAI
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 180 KDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTL 238
KDALNENSQLQ S KQL Q EAEVWK +VSELNKQK+TFEDSKVHAEQVLNDKE+HIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 239 TERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK 298
T L MKD AA+L ED TDDDNLELE+NS+ ENGA LD+P KGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
Query: 299 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE 358
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FE+ENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
Query: 359 LYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIH 418
YQENEMKL+RKLTVEENYR+E+EEKLS+V+EKIS ATE LETYRK AKDLEEELERT+H
Sbjct: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISRATEGLETYRKLAKDLEEELERTVH 449
Query: 419 SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDV 478
YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTETELKFELLEKDP ALDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
Query: 479 PNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLD 538
NTAFGREHSP PSPLG PSSETRAF SP TLLE PLRLSP+LPGGGGRG PGNPLD
Sbjct: 510 SNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLD 569
Query: 539 HQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRF 598
HQITNERGE S DRL DPHRAPSDTGSLS P +QDRRMMFPPPGQSYPDS LPPQR+DRF
Sbjct: 570 HQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTLPPQREDRF 629
Query: 599 CSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEAT 658
SNS RLSGPAE RSF M SLDKMD SMPSEMESSRND KDDLGNLNVPDSSLPAENEAT
Sbjct: 630 YSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 659 GPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAP 718
GPG +PPPLAPI GPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP DFPGPP AP
Sbjct: 690 GPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 719 FAMRNVYPPRGFPPYLPPRPGFFPPP 744
FAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 750 FAMRNIYPPRGLPPYLHPRPGFYPNP 775
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 265 bits (678), Expect = 9e-71
Identities = 224/783 (28%), Positives = 369/783 (47%), Gaps = 108/783 (13%)
Query: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
++P + YG PW+ V A +G + FLWR+ V+ R+Y E++++ L +++E
Sbjct: 1168 VQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKEN 1227
Query: 61 SKLLEKFSLVQ---KEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSE-LEDEI 116
++L++K S + KE + + E+ ++ EA + + T EK N E L+D
Sbjct: 1228 TELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEK----NQEILDDTA 1283
Query: 117 LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLK 176
L L+ E+ ++ + +L+++ K I+ L+D S+ +E ++ +++EE++K
Sbjct: 1284 KNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEEKVK 1343
Query: 177 IAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIK 236
EN++L++ ++QL QE E W + +EL++Q +FE S+ E L K+ +I
Sbjct: 1344 SECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNIN 1403
Query: 237 TLTE-----RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAA 291
LT LL+ + + + D D L + E G + K +K+++ +
Sbjct: 1404 ALTNCITQLNLLECESESEGQNKGGNDSDEL-----ANGEVGGDRNEKMKNQIKQMMDVS 1458
Query: 292 KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQ 351
+ ++ +E + + ++L TK L + +K L+ ++ SLQ+ E+E + L+Q
Sbjct: 1459 RTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLEDECKTLRQ 1518
Query: 352 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 411
K++++ ELYQ+ EM L +KL+ EE R E+E +LS DEK A EE++TY++R +++E+
Sbjct: 1519 KVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTYKRRIEEMED 1578
Query: 412 ELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 471
EL++T S++ QI +HEKKAH+NWL AR AER + + ++E A+ R KL E K +L++
Sbjct: 1579 ELQKTERSFKNQIATHEKKAHENWLKARAAERAIAEEKREAANLRHKLLELTQKMAMLQE 1638
Query: 472 DPYAL----DVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGG 527
+P + PNT P + PS + SPP +E P+R PL
Sbjct: 1639 EPVIVKPMPGKPNTQNPPRRGPLSQNGSFGPSPVSGGECSPPLTVEPPVR--PL------ 1690
Query: 528 RGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPD 587
++ +R P S+ GS+ P P P S
Sbjct: 1691 -------------------SATLNRRDMPR---SEFGSVDGP--------LPHPRWSAEA 1720
Query: 588 SALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNV- 646
S P S S SG A + + GS P+ + D G +N+
Sbjct: 1721 SGKP--------SPSDPGSGTATMMN------SSSRGSSPTRVL--------DEGKVNMA 1758
Query: 647 -----PDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGP-PFPPP-PPGAMF 699
P +P + G G VPPP+ GP P GPF GP P PPP PG
Sbjct: 1759 PKGPPPFPGVPLMSTPMG-GPVPPPIR--YGP--PPQLCGPF---GPRPLPPPFGPGMRP 1810
Query: 700 GASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLP-----PRPGFFPP---PPHSEGRS 751
F PG PG P R P G P+ P PR F P PP + G
Sbjct: 1811 PLGLREFAPGVPPGRRDLPLHPRGFLP--GHAPFRPLGSLGPREYFIPGTRLPPPTHGPQ 1868
Query: 752 EFP 754
E+P
Sbjct: 1869 EYP 1871
Score = 42.0 bits (97), Expect = 0.002
Identities = 87/430 (20%), Positives = 175/430 (40%), Gaps = 48/430 (11%)
Query: 51 LMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK-LNRSN 109
L++S +E+ L ++F QK + +E+E+ L++ S + ++ + +SL EK L++
Sbjct: 924 LIISSFFKEQQSL-QRF---QKYFNVHELEALLQEMSSKLKSAQQESLPYNMEKVLDKVF 979
Query: 110 SELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQ 169
E +IL + +++ + + + D+ ++ +E+ L
Sbjct: 980 RASESQILSIAEKMLDTRVAENR------DLGMNENNIFEEAAVLDDIQDLIYFVRYKHS 1033
Query: 170 MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ-VL 228
EE + + L E + Q L E +E+ +ELN V + H +Q V+
Sbjct: 1034 TAEETATLVMAPPLEEGLGGAMEEMQPLHEDNFSREKTAELN---VQVPEEPTHLDQRVI 1090
Query: 229 NDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE-LEMNSESENGAYLDNPPKGALKKL 287
D +H ++++ KD G T+D ++ ++ N + E
Sbjct: 1091 GD--THASEVSQKPNTEKDLDP--GPVTTEDTPMDAIDANKQPET--------------- 1131
Query: 288 IHAAKLNASLKTLEGERNQIYIQLSEVDKT-KEELTEHIK------NLQTEQASLQSENT 340
AA+ AS+ LE IY + + K+ L + ++ L + + +
Sbjct: 1132 --AAEEPASVTPLENAILLIYSFMFYLTKSLVATLPDDVQPGPDFYGLPWKPVFITAFLG 1189
Query: 341 HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELE 400
+ L V +YQ E ++ KL E +KLS ++KI + + ++
Sbjct: 1190 IASFAIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQ 1249
Query: 401 TYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLT 460
RK+ L +E + Y+ +I + EK A+N L R++N N+ ++
Sbjct: 1250 ETRKQNMILSDEAIK----YKDKIKTLEKNQEILDDTAKNLRVMLESEREQNVKNQDLIS 1305
Query: 461 ETELKFELLE 470
E + E L+
Sbjct: 1306 ENKKSIEKLK 1315
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 98.6 bits (244), Expect = 2e-20
Identities = 96/452 (21%), Positives = 197/452 (43%), Gaps = 44/452 (9%)
Query: 60 KSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCL 119
+SK + + ++++Y E + K ++E + ++ E +L E E +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
+ +++ ++H + D+ + + E+E +SL S++ + ++ + + +L +
Sbjct: 501 QSYIRKRTAEHEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 180 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ---VLNDKESHIK 236
+ +N+ LQ + +L++ E K Q+ + + Q + V AE+ V+ +K+ IK
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 237 TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS 296
+ L +D E++ D N+ + +E + L N A +L
Sbjct: 618 QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL--------- 668
Query: 297 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ------ 350
E + +Y++ ++ +E+L I N E L +N ++E QKLQ
Sbjct: 669 ----EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQ 724
Query: 351 ---QKLKVMTELYQENEMKLHRKLTVEENYRL------EKEEKLSKVDEKISHATEELET 401
++ M + QE + KL TVEE KEE+L+ + + S T+E++
Sbjct: 725 PNKDVVEQMEKCIQEKDEKLK---TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD 781
Query: 402 YRKRAKD------LEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 455
+ + D L EEL++ IH G+I S E+ L N E+ + DL++E
Sbjct: 782 LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 456 RQKLTETEL-KFELLEKDPYALDVPNTAFGRE 486
++++ +L K + L ++ N G+E
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Score = 70.9 bits (172), Expect = 4e-12
Identities = 102/442 (23%), Positives = 192/442 (43%), Gaps = 41/442 (9%)
Query: 46 EKKLALMLSGLIEEKSKLLE---------KFSLVQKEYEGYEVESSLKDASFEKEATEAQ 96
EK L ++ ++E LL+ K L +KE + L+D E E+ +A
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 97 SLEATCEKLNRSNS-----ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 151
E L ++S ELE + E ELK ++ E++ ++ ++ +Q ++DE+
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 970
Query: 152 KSLKSQVAEAK----MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 207
K KSQ+ + K F +EE LK+ I + E S L L E +++
Sbjct: 971 KLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 208 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 267
++L ++ ++ E++L DK + KT ER ++ + + +++ ++ +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVN--KTSKERQQQV-EAVELEAKEVLKKLFPKVSVP 1086
Query: 268 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEELTE 323
S G +L K A K+ + + +K LE E ++++ L E +K K L E
Sbjct: 1087 SNLSYGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAE 1145
Query: 324 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLE 380
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E
Sbjct: 1146 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1205
Query: 381 KEEKLSKVDEKISHATEELETY---RKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 437
+E ++ ++ A E TY + KDL EL++ + + + ++ + L
Sbjct: 1206 REH----LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELN---LL 1258
Query: 438 ARNAERNLNDLRKENAHNRQKL 459
L LR E + RQK+
Sbjct: 1259 KAQLNETLTKLRTEQ-NERQKV 1279
Score = 38.9 bits (89), Expect = 0.018
Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 169 QMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVL 228
+ ++E ++ KD L + S+ + L ++ KE+ S V + +
Sbjct: 274 ETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEK-------------SGVIQDALK 320
Query: 229 NDKESHIKTLTERLLKMKDWAAMLGEDI--TDD--DNLELEMNSESENGAYLDNPPKGAL 284
+ + TL +L + A + ED T D L EM +E E
Sbjct: 321 KSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKE------------- 367
Query: 285 KKLIHAAKLNASLKTLEGE----RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN- 339
+ + ++ + TLE E +N+I++ E + + + + + ++ E A L+ EN
Sbjct: 368 RSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENG 427
Query: 340 ---THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT 396
N +L+ K +++ +L +LT E+ +L++EE K E+ A
Sbjct: 428 ILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELT-EKTGKLQQEEVQKKNAEQ---AA 483
Query: 397 EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNR 456
+L+ + A+ EE++ I + + ++ ++A N ++L+ + ++
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 457 QKLTE 461
Q+L +
Sbjct: 544 QQLEQ 548
Score = 30.4 bits (67), Expect = 6.5
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 12/157 (7%)
Query: 53 LSGLIEEKSKLLEKFSLVQKEYEGYEVE-SSLKDASFEKEATEAQSLEATCEKLNRSNSE 111
+ L E+ L + + E Y E LKD E + + L+ + + R N E
Sbjct: 1199 IENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ----KKLDDSYSEAVRQNEE 1254
Query: 112 LEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLE-DESKSLKSQ-----VAEAKMTF 165
L L + L + +++ +E+ ++ D+ K QSLE +SK +K+ + + ++
Sbjct: 1255 LNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSP 1314
Query: 166 KIFQMNEERLKIAIKDALNENSQ-LQESQKQLLQEAE 201
+ +E + +++ + + Q LQ +QL +E E
Sbjct: 1315 ETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 98.6 bits (244), Expect = 2e-20
Identities = 96/452 (21%), Positives = 197/452 (43%), Gaps = 44/452 (9%)
Query: 60 KSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCL 119
+SK + + ++++Y E + K ++E + ++ E +L E E +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
+ +++ ++H + D+ + + E+E +SL S++ + ++ + + +L +
Sbjct: 501 QSYIRKRTAEHEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 180 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ---VLNDKESHIK 236
+ +N+ LQ + +L++ E K Q+ + + Q + V AE+ V+ +K+ IK
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 237 TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS 296
+ L +D E++ D N+ + +E + L N A +L
Sbjct: 618 QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL--------- 668
Query: 297 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ------ 350
E + +Y++ ++ +E+L I N E L +N ++E QKLQ
Sbjct: 669 ----EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQ 724
Query: 351 ---QKLKVMTELYQENEMKLHRKLTVEENYRL------EKEEKLSKVDEKISHATEELET 401
++ M + QE + KL TVEE KEE+L+ + + S T+E++
Sbjct: 725 PNKDVVEQMEKCIQEKDEKLK---TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD 781
Query: 402 YRKRAKD------LEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 455
+ + D L EEL++ IH G+I S E+ L N E+ + DL++E
Sbjct: 782 LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 456 RQKLTETEL-KFELLEKDPYALDVPNTAFGRE 486
++++ +L K + L ++ N G+E
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Score = 66.6 bits (161), Expect = 8e-11
Identities = 94/422 (22%), Positives = 179/422 (42%), Gaps = 63/422 (14%)
Query: 46 EKKLALMLSGLIEEKSKLLE---------KFSLVQKEYEGYEVESSLKDASFEKEATEAQ 96
EK L ++ ++E LL+ K L +KE + L+D E E+ +A
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 97 SLEATCEKLNRSNS-----ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 151
E L ++S ELE + E ELK ++ E++ ++ ++ +Q ++DE+
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 970
Query: 152 KSLKSQVAEAK----MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 207
K KSQ+ + K F +EE LK+ + E +K++ + +W E
Sbjct: 971 KLFKSQIEQLKQQNYQQASSFPPHEELLKV-----------ISEREKEI---SGLWNELD 1016
Query: 208 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 267
S +D+ H + N+++ ++ + L+ K+ L ++ NL
Sbjct: 1017 S--------LKDAVEHQRKKNNERQQQVEAVE---LEAKEVLKKLFPKVSVPSNLSY--- 1062
Query: 268 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEELTE 323
G +L K A K+ + + +K LE E ++++ L E +K K L E
Sbjct: 1063 -----GEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAE 1116
Query: 324 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLE 380
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E
Sbjct: 1117 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1176
Query: 381 KEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARN 440
+E ++ ++ A E TY ++L+ +L T+ + + +K A D A ++
Sbjct: 1177 REH----LEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQS 1232
Query: 441 AE 442
E
Sbjct: 1233 LE 1234
Score = 38.9 bits (89), Expect = 0.018
Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 169 QMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVL 228
+ ++E ++ KD L + S+ + L ++ KE+ S V + +
Sbjct: 274 ETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEK-------------SGVIQDALK 320
Query: 229 NDKESHIKTLTERLLKMKDWAAMLGEDI--TDD--DNLELEMNSESENGAYLDNPPKGAL 284
+ + TL +L + A + ED T D L EM +E E
Sbjct: 321 KSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKE------------- 367
Query: 285 KKLIHAAKLNASLKTLEGE----RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN- 339
+ + ++ + TLE E +N+I++ E + + + + + ++ E A L+ EN
Sbjct: 368 RSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENG 427
Query: 340 ---THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT 396
N +L+ K +++ +L +LT E+ +L++EE K E+ A
Sbjct: 428 ILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELT-EKTGKLQQEEVQKKNAEQ---AA 483
Query: 397 EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNR 456
+L+ + A+ EE++ I + + ++ ++A N ++L+ + ++
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 457 QKLTE 461
Q+L +
Sbjct: 544 QQLEQ 548
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 98.6 bits (244), Expect = 2e-20
Identities = 96/452 (21%), Positives = 197/452 (43%), Gaps = 44/452 (9%)
Query: 60 KSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCL 119
+SK + + ++++Y E + K ++E + ++ E +L E E +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
+ +++ ++H + D+ + + E+E +SL S++ + ++ + + +L +
Sbjct: 501 QSYIRKRTAEHEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 180 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ---VLNDKESHIK 236
+ +N+ LQ + +L++ E K Q+ + + Q + V AE+ V+ +K+ IK
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 237 TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS 296
+ L +D E++ D N+ + +E + L N A +L
Sbjct: 618 QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL--------- 668
Query: 297 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ------ 350
E + +Y++ ++ +E+L I N E L +N ++E QKLQ
Sbjct: 669 ----EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQ 724
Query: 351 ---QKLKVMTELYQENEMKLHRKLTVEENYRL------EKEEKLSKVDEKISHATEELET 401
++ M + QE + KL TVEE KEE+L+ + + S T+E++
Sbjct: 725 PNKDVVEQMEKCIQEKDEKLK---TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD 781
Query: 402 YRKRAKD------LEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 455
+ + D L EEL++ IH G+I S E+ L N E+ + DL++E
Sbjct: 782 LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 456 RQKLTETEL-KFELLEKDPYALDVPNTAFGRE 486
++++ +L K + L ++ N G+E
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Score = 70.9 bits (172), Expect = 4e-12
Identities = 102/442 (23%), Positives = 192/442 (43%), Gaps = 41/442 (9%)
Query: 46 EKKLALMLSGLIEEKSKLLE---------KFSLVQKEYEGYEVESSLKDASFEKEATEAQ 96
EK L ++ ++E LL+ K L +KE + L+D E E+ +A
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 97 SLEATCEKLNRSNS-----ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 151
E L ++S ELE + E ELK ++ E++ ++ ++ +Q ++DE+
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 970
Query: 152 KSLKSQVAEAK----MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 207
K KSQ+ + K F +EE LK+ I + E S L L E +++
Sbjct: 971 KLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 208 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 267
++L ++ ++ E++L DK + KT ER ++ + + +++ ++ +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVN--KTSKERQQQV-EAVELEAKEVLKKLFPKVSVP 1086
Query: 268 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEELTE 323
S G +L K A K+ + + +K LE E ++++ L E +K K L E
Sbjct: 1087 SNLSYGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAE 1145
Query: 324 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLE 380
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E
Sbjct: 1146 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1205
Query: 381 KEEKLSKVDEKISHATEELETY---RKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 437
+E ++ ++ A E TY + KDL EL++ + + + ++ + L
Sbjct: 1206 REH----LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELN---LL 1258
Query: 438 ARNAERNLNDLRKENAHNRQKL 459
L LR E + RQK+
Sbjct: 1259 KAQLNETLTKLRTEQ-NERQKV 1279
Score = 38.9 bits (89), Expect = 0.018
Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 169 QMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVL 228
+ ++E ++ KD L + S+ + L ++ KE+ S V + +
Sbjct: 274 ETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEK-------------SGVIQDALK 320
Query: 229 NDKESHIKTLTERLLKMKDWAAMLGEDI--TDD--DNLELEMNSESENGAYLDNPPKGAL 284
+ + TL +L + A + ED T D L EM +E E
Sbjct: 321 KSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKE------------- 367
Query: 285 KKLIHAAKLNASLKTLEGE----RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN- 339
+ + ++ + TLE E +N+I++ E + + + + + ++ E A L+ EN
Sbjct: 368 RSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENG 427
Query: 340 ---THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT 396
N +L+ K +++ +L +LT E+ +L++EE K E+ A
Sbjct: 428 ILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELT-EKTGKLQQEEVQKKNAEQ---AA 483
Query: 397 EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNR 456
+L+ + A+ EE++ I + + ++ ++A N ++L+ + ++
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 457 QKLTE 461
Q+L +
Sbjct: 544 QQLEQ 548
Score = 30.4 bits (67), Expect = 6.5
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 12/157 (7%)
Query: 53 LSGLIEEKSKLLEKFSLVQKEYEGYEVE-SSLKDASFEKEATEAQSLEATCEKLNRSNSE 111
+ L E+ L + + E Y E LKD E + + L+ + + R N E
Sbjct: 1199 IENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ----KKLDDSYSEAVRQNEE 1254
Query: 112 LEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLE-DESKSLKSQ-----VAEAKMTF 165
L L + L + +++ +E+ ++ D+ K QSLE +SK +K+ + + ++
Sbjct: 1255 LNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSP 1314
Query: 166 KIFQMNEERLKIAIKDALNENSQ-LQESQKQLLQEAE 201
+ +E + +++ + + Q LQ +QL +E E
Sbjct: 1315 ETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 85.1 bits (209), Expect = 2e-16
Identities = 108/453 (23%), Positives = 198/453 (43%), Gaps = 43/453 (9%)
Query: 50 ALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSN 109
+L L +E+ S+ E QK G+EV + L + K E QSL T E+L +
Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSL-GHEV-NELTSSRLLKLEMENQSLTKTVEELRTTV 483
Query: 110 SELE---DEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 166
+E +IL +EKE + K + + + +Q+ ++ SK L + A+ + T +
Sbjct: 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 167 IFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE-QVSELNKQ------------ 213
+ N ER IK EN L ++ L Q +++ E +V ++ K+
Sbjct: 544 TLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS 600
Query: 214 ----KVTFEDSKVHAE-QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNS 268
K+ FE ++ E + +K + L L ++ +L + IT+ ++ +
Sbjct: 601 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Query: 269 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 328
+ + L+ + K L L L++LE E + QL E + E +K
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS----QLDEENLELRRNVESLKCA 716
Query: 329 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENE-MKLHRKLTVEENYRLEKEEKLSK 387
+ A LQ EN E+E ++L++ L+++ +++ E +++ + EN RL+K L
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK--TLEN 774
Query: 388 VDEKISHATEELETYRKRAKDLEEELER-TIHSYQGQIISHEKKAHDNWLAARNAERNLN 446
++KI EL+ + L++ LE I S + + + E K+ + E++
Sbjct: 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKDKK 832
Query: 447 DLRKENAHNRQK-------LTETELKFELLEKD 472
L KEN RQ+ L E +K LEK+
Sbjct: 833 QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Score = 82.4 bits (202), Expect = 1e-15
Identities = 117/495 (23%), Positives = 203/495 (41%), Gaps = 84/495 (16%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE-----KEATEAQSLE 99
+ ++L + GL E +L + K+ + ++ES L+D E K E +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 100 ATCEKLNRSNSELEDEILCLEKELK--EEKSKHSEQ-----DELMADISKRIQSLEDESK 152
E+L + N LE E LEK+ K E+++K Q D + + + +I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 153 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 212
+L ++ K + + E+ K +K A + L ++ L+ E ++ ++L K
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Query: 213 QKVTFEDSKVHAEQVLND--------------------------KESHIKTLTERLLKMK 246
E ++ E++L+D KE I L RL +
Sbjct: 928 LTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEEST 987
Query: 247 DWAAMLGEDI-TDDDNLELEMNSESENGAYLDNPP----------------KGALK---K 286
++ L +++ T N E + E +PP + LK +
Sbjct: 988 NYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR 1047
Query: 287 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENEN 346
LI + NA TL+ E+ + QL +++ L I LQ + SLQ +NT + +N
Sbjct: 1048 LIEVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1104
Query: 347 QKLQQKLKVM----TELYQENEMKLHRKLTVE-ENYRLEKE-EKLSKVDEKISHATEELE 400
KLQ + + T L +N L ++ ++E EN + KE E L + + + E+LE
Sbjct: 1105 AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLE 1164
Query: 401 TYRKRAKDLEEELERTIHSYQGQIISHE--KKAHDNW-LAARNAERNLNDLRKENA--HN 455
ER Y+ I H K AH N + R+ E N L K+ +
Sbjct: 1165 LLH----------ERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1214
Query: 456 RQKLTETELKFELLE 470
+K+ + E + LLE
Sbjct: 1215 LEKMLKVEQEKMLLE 1229
Score = 78.6 bits (192), Expect = 2e-14
Identities = 115/476 (24%), Positives = 200/476 (42%), Gaps = 75/476 (15%)
Query: 36 SVRSRLYVGREKKLA------LMLSGLIEEKSKLLEKFSL----VQKEYEGY-------- 77
S+R R + E ++ +L I+E S L K ++KE E Y
Sbjct: 569 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 78 EVESSLKDASFEKEATEAQ--SLEATCEK---LNRSNSELEDEILCLEKELKEEKSKHSE 132
E+E+ L E E + + +L+ TCEK L + NSELE E L+K L K+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN---- 684
Query: 133 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALN---ENSQL 189
++ +++SLE E+ L + E + N E LK A EN +L
Sbjct: 685 -------LTFQLESLEKENSQLDEENLELRR-------NVESLKCASMKMAQLQLENKEL 730
Query: 190 QESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWA 249
+ ++QL + E+ K + + +V+++ + +++ E+ K + + +++D
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 250 AMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 309
E+ T NLE E+ S+ L+ K ++ ++L K LE E ++
Sbjct: 791 M---ENQTLQKNLE-ELKISSKRLEQLEKENKSLEQE---TSQLEKDKKQLEKENKRLRQ 843
Query: 310 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 369
Q D T EE I NL+ E +L E ++ +L++ K EL + + +
Sbjct: 844 QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 370 KLTVEENYRLE--KEEKLSKVDEKISHATE------------ELETYRKRAKDLEEELER 415
+T+ E+ E K ++++ EK++H E E T R K LE +LE
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLES 963
Query: 416 TIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 471
T+ + I EK A E L + N RQ+L + +E L++
Sbjct: 964 TLK--KSLEIKEEKIA--------ALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Score = 68.9 bits (167), Expect = 2e-11
Identities = 92/452 (20%), Positives = 200/452 (44%), Gaps = 48/452 (10%)
Query: 56 LIEEKSKLLE-KFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEAT-CEKLNRSNSELE 113
L++ K +L + + L + + E + S + A ++ +A +A +KL S +
Sbjct: 274 LLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYK 333
Query: 114 DEILCLE------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKI 167
+ + +E +ELKE+ E ++ D + ++ D+ L+ + + K
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHD 393
Query: 168 FQMNEERLKIAIKDALNENSQLQESQKQLLQEA--EVWK-------EQVSELNKQKVTFE 218
+M + + I++ + EN L+ +QKQ + E+ W+ ++SE ++ + E
Sbjct: 394 MEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Query: 219 DSKVHAEQVLN---DKESHIKTLTE-------------RLLKMKDWAAMLGEDITDDDNL 262
+++ + ++L + +S KT+ E ++LKM+ L + + + L
Sbjct: 454 VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKV---EIL 510
Query: 263 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL-EGERNQIYIQLSEVDKTKEEL 321
E E+ E ++ N K +K+ A+L +++TL E QI I +++ E L
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLRENSERQIKI----LEQENEHL 563
Query: 322 TEHIKNL-QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 380
+ + +L Q Q S ++ E EN+ L + +K + + E + R++ E + E
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFE-KRQIKKELEHYKE 622
Query: 381 KEEKLSKVDEKISHATEELETYRKRAKDLEEELER--TIHSYQGQIISHEKKAHDNWLAA 438
K E+ +++ ++ H +E E +K+ +L+ E+ + ++ +K +
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF 682
Query: 439 RNAERNLNDLRKENAHNRQKLTETELKFELLE 470
+N L L KEN+ ++ E E L+
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Score = 60.1 bits (144), Expect = 8e-09
Identities = 95/452 (21%), Positives = 201/452 (44%), Gaps = 79/452 (17%)
Query: 45 REKKLALMLSGLIEEKS---KLLEKFSLVQKEYEGYE--------VESSLKDASFEKEAT 93
+E+K+A + + L E + +L ++ V+K YE + V+SS S E
Sbjct: 972 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS-PPISGEDNKW 1030
Query: 94 EAQSLEATCEKLN---------RSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 144
E +S E T E L R+N+ L+ E L+ +LK+ +++++ + + ++
Sbjct: 1031 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1090
Query: 145 QSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 204
SL++++ +L++Q A+ Q+ L +N+N+QL L+Q++ +
Sbjct: 1091 VSLQEQNTTLQTQNAK-------LQVENSTLNSQSTSLMNQNAQL------LIQQSSLEN 1137
Query: 205 EQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDIT---DDDN 261
E S + ++ ED K + ++ D E ++ L ER + ++ +++ + T N
Sbjct: 1138 ENESVIKER----EDLKSLYDSLIKDHEK-LELLHER--QASEYESLISKHGTLKSAHKN 1190
Query: 262 LELEMNSESENGAYLDNPPKGALKKLIHAAKL--------NASLKTLEGERNQIYIQLSE 313
LE+E + L KG L+ L K+ N + +T+ E ++ +
Sbjct: 1191 LEVEHRDLEDRYNQLLKQ-KGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1249
Query: 314 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 373
++ T +L + + LQT+ +L+S + + E +L+ + + E YQ+ ++ +
Sbjct: 1250 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDI-----TST 1304
Query: 374 EENYRLEKEEKL-SKVDEKISHATEELETYRKRAKDLEE---ELERTIHSYQGQIISHEK 429
+ N + E +L ++E+ H ++++T + + L E E + H Q Q I
Sbjct: 1305 KLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYID--- 1361
Query: 430 KAHDNWLAARNAERNLNDLRKENAHNRQKLTE 461
LN+LR++ +K+ +
Sbjct: 1362 --------------KLNELRRQKEKLEEKIMD 1379
Score = 41.2 bits (95), Expect = 0.004
Identities = 44/212 (20%), Positives = 86/212 (40%), Gaps = 11/212 (5%)
Query: 43 VGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATC 102
+ + L + LI++ KL EYE + ++ + E + LE
Sbjct: 1143 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1202
Query: 103 EKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 162
+L + +LED LEK LK E+ K +++ ++ + L E+ L ++
Sbjct: 1203 NQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1258
Query: 163 MTFKIFQMNEERLKIAIKDALNEN-------SQLQESQKQLLQEAEVWKEQVSELNKQKV 215
++ Q + + LK + ++ E S+L+E +QL + Q L++ K
Sbjct: 1259 KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKG 1318
Query: 216 TFEDSKVHAEQVLNDKESHIKTLTERLLKMKD 247
E+ H + +TL E+ ++ KD
Sbjct: 1319 NLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1350
Score = 35.0 bits (79), Expect = 0.27
Identities = 44/198 (22%), Positives = 88/198 (44%), Gaps = 23/198 (11%)
Query: 44 GREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCE 103
G +L S L++E L ++ ++E + +A F K + Q L+ T
Sbjct: 1245 GENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITST 1304
Query: 104 KLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM 163
KLN + E+L K EE+++H + +IQ+L ++++L Q E+K
Sbjct: 1305 KLNN-----QCELLSQLKGNLEEENRH---------LLDQIQTLMLQNRTLLEQNMESKD 1350
Query: 164 TFKIFQMNEERLKIAIKDALNE-NSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK- 221
F + E+R I D LNE Q ++ +++++ + + + +T + K
Sbjct: 1351 LFHV----EQRQYI---DKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKL 1403
Query: 222 VHAEQVLNDKESHIKTLT 239
+ +++ +N + TLT
Sbjct: 1404 IKSKKDINRERQKSLTLT 1421
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 85.1 bits (209), Expect = 2e-16
Identities = 108/453 (23%), Positives = 198/453 (43%), Gaps = 43/453 (9%)
Query: 50 ALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSN 109
+L L +E+ S+ E QK G+EV + L + K E QSL T E+L +
Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSL-GHEV-NELTSSRLLKLEMENQSLTKTVEELRTTV 483
Query: 110 SELE---DEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 166
+E +IL +EKE + K + + + +Q+ ++ SK L + A+ + T +
Sbjct: 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 167 IFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE-QVSELNKQ------------ 213
+ N ER IK EN L ++ L Q +++ E +V ++ K+
Sbjct: 544 TLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS 600
Query: 214 ----KVTFEDSKVHAE-QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNS 268
K+ FE ++ E + +K + L L ++ +L + IT+ ++ +
Sbjct: 601 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Query: 269 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 328
+ + L+ + K L L L++LE E + QL E + E +K
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS----QLDEENLELRRNVESLKCA 716
Query: 329 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENE-MKLHRKLTVEENYRLEKEEKLSK 387
+ A LQ EN E+E ++L++ L+++ +++ E +++ + EN RL+K L
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK--TLEN 774
Query: 388 VDEKISHATEELETYRKRAKDLEEELER-TIHSYQGQIISHEKKAHDNWLAARNAERNLN 446
++KI EL+ + L++ LE I S + + + E K+ + E++
Sbjct: 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKDKK 832
Query: 447 DLRKENAHNRQK-------LTETELKFELLEKD 472
L KEN RQ+ L E +K LEK+
Sbjct: 833 QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Score = 82.8 bits (203), Expect = 1e-15
Identities = 117/494 (23%), Positives = 203/494 (41%), Gaps = 83/494 (16%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE-----KEATEAQSLE 99
+ ++L + GL E +L + K+ + ++ES L+D E K E +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 100 ATCEKLNRSNSELEDEILCLEKELK--EEKSKHSEQ-----DELMADISKRIQSLEDESK 152
E+L + N LE E LEK+ K E+++K Q D + + + +I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 153 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 212
+L ++ K + + E+ K +K A + L ++ L+ E ++ ++L K
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Query: 213 QKVTFEDSKVHAEQVLND-------------------------KESHIKTLTERLLKMKD 247
E ++ E++L+D KE I L RL + +
Sbjct: 928 LTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN 987
Query: 248 WAAMLGEDI-TDDDNLELEMNSESENGAYLDNPP----------------KGALK---KL 287
+ L +++ T N E + E +PP + LK +L
Sbjct: 988 YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRL 1047
Query: 288 IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQ 347
I + NA TL+ E+ + QL +++ L I LQ + SLQ +NT + +N
Sbjct: 1048 IEVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1104
Query: 348 KLQQKLKVM----TELYQENEMKLHRKLTVE-ENYRLEKE-EKLSKVDEKISHATEELET 401
KLQ + + T L +N L ++ ++E EN + KE E L + + + E+LE
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Query: 402 YRKRAKDLEEELERTIHSYQGQIISHE--KKAHDNW-LAARNAERNLNDLRKENA--HNR 456
ER Y+ I H K AH N + R+ E N L K+ +
Sbjct: 1165 LH----------ERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDL 1214
Query: 457 QKLTETELKFELLE 470
+K+ + E + LLE
Sbjct: 1215 EKMLKVEQEKMLLE 1228
Score = 80.9 bits (198), Expect = 4e-15
Identities = 109/467 (23%), Positives = 203/467 (43%), Gaps = 58/467 (12%)
Query: 36 SVRSRLYVGREKKLA------LMLSGLIEEKSKLLEKFSL----VQKEYEGY-------- 77
S+R R + E ++ +L I+E S L K ++KE E Y
Sbjct: 569 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 78 EVESSLKDASFEKEATEAQ--SLEATCEK---LNRSNSELEDEILCLEKELKEEKSKHSE 132
E+E+ L E E + + +L+ TCEK L + NSELE E L+K L K+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN---- 684
Query: 133 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALN---ENSQL 189
++ +++SLE E+ L + E + N E LK A EN +L
Sbjct: 685 -------LTFQLESLEKENSQLDEENLELRR-------NVESLKCASMKMAQLQLENKEL 730
Query: 190 QESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWA 249
+ ++QL + E+ K + + +V+++ + +++ E+ K + + +++D
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 250 AMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 309
E+ T NLE E+ S+ L+ K ++ ++L K LE E ++
Sbjct: 791 M---ENQTLQKNLE-ELKISSKRLEQLEKENKSLEQE---TSQLEKDKKQLEKENKRLRQ 843
Query: 310 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 369
Q D T EE I NL+ E +L E ++ +L++ K EL + + +
Sbjct: 844 QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 370 KLTVEENYRLE--KEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISH 427
+T+ E+ E K ++++ EK++H E++ ++R E+ + + ++ S
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEST 963
Query: 428 EKKA---HDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 471
KK+ + +AA E L + N RQ+L + +E L++
Sbjct: 964 LKKSLEIKEEKIAA--LEARLEESTNYNQQLRQELKTVKKNYEALKQ 1008
Score = 68.9 bits (167), Expect = 2e-11
Identities = 92/452 (20%), Positives = 200/452 (44%), Gaps = 48/452 (10%)
Query: 56 LIEEKSKLLE-KFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEAT-CEKLNRSNSELE 113
L++ K +L + + L + + E + S + A ++ +A +A +KL S +
Sbjct: 274 LLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYK 333
Query: 114 DEILCLE------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKI 167
+ + +E +ELKE+ E ++ D + ++ D+ L+ + + K
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHD 393
Query: 168 FQMNEERLKIAIKDALNENSQLQESQKQLLQEA--EVWK-------EQVSELNKQKVTFE 218
+M + + I++ + EN L+ +QKQ + E+ W+ ++SE ++ + E
Sbjct: 394 MEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Query: 219 DSKVHAEQVLN---DKESHIKTLTE-------------RLLKMKDWAAMLGEDITDDDNL 262
+++ + ++L + +S KT+ E ++LKM+ L + + + L
Sbjct: 454 VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKV---EIL 510
Query: 263 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL-EGERNQIYIQLSEVDKTKEEL 321
E E+ E ++ N K +K+ A+L +++TL E QI I +++ E L
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLRENSERQIKI----LEQENEHL 563
Query: 322 TEHIKNL-QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 380
+ + +L Q Q S ++ E EN+ L + +K + + E + R++ E + E
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFE-KRQIKKELEHYKE 622
Query: 381 KEEKLSKVDEKISHATEELETYRKRAKDLEEELER--TIHSYQGQIISHEKKAHDNWLAA 438
K E+ +++ ++ H +E E +K+ +L+ E+ + ++ +K +
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF 682
Query: 439 RNAERNLNDLRKENAHNRQKLTETELKFELLE 470
+N L L KEN+ ++ E E L+
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Score = 60.1 bits (144), Expect = 8e-09
Identities = 95/452 (21%), Positives = 201/452 (44%), Gaps = 79/452 (17%)
Query: 45 REKKLALMLSGLIEEKS---KLLEKFSLVQKEYEGYE--------VESSLKDASFEKEAT 93
+E+K+A + + L E + +L ++ V+K YE + V+SS S E
Sbjct: 971 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS-PPISGEDNKW 1029
Query: 94 EAQSLEATCEKLN---------RSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 144
E +S E T E L R+N+ L+ E L+ +LK+ +++++ + + ++
Sbjct: 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Query: 145 QSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 204
SL++++ +L++Q A+ Q+ L +N+N+QL L+Q++ +
Sbjct: 1090 VSLQEQNTTLQTQNAK-------LQVENSTLNSQSTSLMNQNAQL------LIQQSSLEN 1136
Query: 205 EQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDIT---DDDN 261
E S + ++ ED K + ++ D E ++ L ER + ++ +++ + T N
Sbjct: 1137 ENESVIKER----EDLKSLYDSLIKDHEK-LELLHER--QASEYESLISKHGTLKSAHKN 1189
Query: 262 LELEMNSESENGAYLDNPPKGALKKLIHAAKL--------NASLKTLEGERNQIYIQLSE 313
LE+E + L KG L+ L K+ N + +T+ E ++ +
Sbjct: 1190 LEVEHRDLEDRYNQLLKQ-KGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1248
Query: 314 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 373
++ T +L + + LQT+ +L+S + + E +L+ + + E YQ+ ++ +
Sbjct: 1249 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDI-----TST 1303
Query: 374 EENYRLEKEEKL-SKVDEKISHATEELETYRKRAKDLEE---ELERTIHSYQGQIISHEK 429
+ N + E +L ++E+ H ++++T + + L E E + H Q Q I
Sbjct: 1304 KLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYID--- 1360
Query: 430 KAHDNWLAARNAERNLNDLRKENAHNRQKLTE 461
LN+LR++ +K+ +
Sbjct: 1361 --------------KLNELRRQKEKLEEKIMD 1378
Score = 41.2 bits (95), Expect = 0.004
Identities = 44/212 (20%), Positives = 86/212 (40%), Gaps = 11/212 (5%)
Query: 43 VGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATC 102
+ + L + LI++ KL EYE + ++ + E + LE
Sbjct: 1142 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1201
Query: 103 EKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 162
+L + +LED LEK LK E+ K +++ ++ + L E+ L ++
Sbjct: 1202 NQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1257
Query: 163 MTFKIFQMNEERLKIAIKDALNEN-------SQLQESQKQLLQEAEVWKEQVSELNKQKV 215
++ Q + + LK + ++ E S+L+E +QL + Q L++ K
Sbjct: 1258 KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKG 1317
Query: 216 TFEDSKVHAEQVLNDKESHIKTLTERLLKMKD 247
E+ H + +TL E+ ++ KD
Sbjct: 1318 NLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1349
Score = 35.0 bits (79), Expect = 0.27
Identities = 44/198 (22%), Positives = 88/198 (44%), Gaps = 23/198 (11%)
Query: 44 GREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCE 103
G +L S L++E L ++ ++E + +A F K + Q L+ T
Sbjct: 1244 GENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITST 1303
Query: 104 KLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM 163
KLN + E+L K EE+++H + +IQ+L ++++L Q E+K
Sbjct: 1304 KLNN-----QCELLSQLKGNLEEENRH---------LLDQIQTLMLQNRTLLEQNMESKD 1349
Query: 164 TFKIFQMNEERLKIAIKDALNE-NSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK- 221
F + E+R I D LNE Q ++ +++++ + + + +T + K
Sbjct: 1350 LFHV----EQRQYI---DKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKL 1402
Query: 222 VHAEQVLNDKESHIKTLT 239
+ +++ +N + TLT
Sbjct: 1403 IKSKKDINRERQKSLTLT 1420
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 84.3 bits (207), Expect = 4e-16
Identities = 108/491 (21%), Positives = 222/491 (45%), Gaps = 48/491 (9%)
Query: 25 AVLFFLW--RSFRSVRSRLYVGREKKLALMLSGLIEEK--SKLLEKFSLVQKEYEGYEV- 79
A+L W R+F V++ ++ K+ +L EK + + E+F +++ E E
Sbjct: 812 ALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEAR 871
Query: 80 --ESSLKDASFEKEATEAQ-SLEATCEKLNRSNSELEDEI---LCLEKELKEEKSKHSEQ 133
E K S +E + Q ++A + LN + + I + LE ++KE + ++
Sbjct: 872 RKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDE 931
Query: 134 DELMADISKRIQSLEDESKSLKSQVAEAKMTF------------KIFQMNEER--LKIAI 179
+E+ A+++ + + LEDE LK + + ++T K+ + EE L I
Sbjct: 932 EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 991
Query: 180 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLT 239
E LQE+ +Q L + +V +++V+ L+K KV E E L ++ L
Sbjct: 992 AKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLE 1051
Query: 240 ERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK-KLIHAAKLNASLK 298
K++ + E I D +N +L++ + + + N ++ + + A +L LK
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLK 1111
Query: 299 TLEGERNQIYIQL-------SEVDKTKEELTEHIKNL--QTEQA----SLQSE-NTHFEN 344
+ ++ +L ++V+K + +L+ ++ + + E+A S+Q E N E
Sbjct: 1112 ENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1171
Query: 345 ENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRK 404
E QK+++ L+ T ++ L +K E+ + L +V +K+ +E ++
Sbjct: 1172 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE---KEKSEFKL 1228
Query: 405 RAKDLEEELERTIHSYQG-QIISH--EKKAHDNWLAARNAERNLNDLRKENAHNRQKLTE 461
D+ +E+ I + + +S E +A++ + A+R+LND + A + +
Sbjct: 1229 ELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRA--KLQTEN 1286
Query: 462 TELKFELLEKD 472
EL +L EK+
Sbjct: 1287 GELARQLEEKE 1297
Score = 77.0 bits (188), Expect = 6e-14
Identities = 99/447 (22%), Positives = 195/447 (43%), Gaps = 61/447 (13%)
Query: 47 KKLALMLSGLIE---EKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEAT 101
K L +S L E E K + + V+K E E E++S+L++A E E + L A
Sbjct: 1505 KNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ 1564
Query: 102 CEKLNRSNSELEDEILCLEKELKEEKSKH-----SEQDELMADISKR------------- 143
E N+ +E+E ++ ++E+++ K H S Q L A+ R
Sbjct: 1565 LE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623
Query: 144 IQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVW 203
+ +E + AEA+ K Q + +I + DA+ N L+E+ + + +
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
Query: 204 KEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE 263
+ ++ EL E S+ AEQ L + ++ L + + + + D+T
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLT------ 1737
Query: 264 LEMNSESENGAY-LDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELT 322
++ SE E N + A K + AA + LK + + +++ K+ +
Sbjct: 1738 -QLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNME 1789
Query: 323 EHIKNLQ-----TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENY 377
+ IK+LQ EQ +L+ + + QKL+ +++ + E E++ +K E
Sbjct: 1790 QTIKDLQHRLDEAEQIALKGG----KKQLQKLEARVREL-----EGELEAEQKRNAESVK 1840
Query: 378 RLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 437
+ K E+ K ++++ TEE + R +DL ++L+ + +Y+ Q E++A+ N
Sbjct: 1841 GMRKSERRIK---ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSK 1897
Query: 438 ARNAERNLNDLRKENAHNRQKLTETEL 464
R + L++ A R + E+++
Sbjct: 1898 FRKVQHELDE-----AEERADIAESQV 1919
Score = 67.4 bits (163), Expect = 5e-11
Identities = 87/411 (21%), Positives = 172/411 (41%), Gaps = 44/411 (10%)
Query: 80 ESSLKDASFEKEATEA-QSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 138
E+ K A ++A EA +++ A C L ++ L++EI L +++ + + D+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 139 DISKRI----QSLEDESKSLKSQVAEAKM----TFKIFQMNEERLKIAIKDALNENSQLQ 190
+ K + Q E+ L+S EA+ FK+ EE L+ ++ EN LQ
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE-HLETFKRENKNLQ 1508
Query: 191 ESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAA 250
E L ++ + V EL K + E K+ + L + E+ ++ ++L+ +
Sbjct: 1509 EEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568
Query: 251 MLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS-----LKTLEGERN 305
+ +I + E + E E +L+ + A + + K +EG+ N
Sbjct: 1569 QIKAEI---ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 306 QIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEM 365
++ IQLS ++ E + +K+LQ+ Q + N L++ + +
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI---------- 1675
Query: 366 KLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRA-KDLEEELERT--IHSYQG 422
VE L + E E++ E+ E RK A ++L E ER +HS
Sbjct: 1676 -------VERRNNLLQAEL-----EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1723
Query: 423 QIISHEKKAHDNWLAARN-AERNLNDLRKENAHNRQKLTETELKFELLEKD 472
+I+ +KK + ++ E + + R ++ +T+ + E L+K+
Sbjct: 1724 SLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE 1774
Score = 61.6 bits (148), Expect = 3e-09
Identities = 92/422 (21%), Positives = 170/422 (40%), Gaps = 34/422 (8%)
Query: 78 EVESSLKDASFE--KEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDE 135
E + SL D + + K TE L E+ S+L L +++++ K + E+ +
Sbjct: 1267 EAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGK 1326
Query: 136 LMADISKRIQSLEDESKSLKSQV-----AEAKMTFKIFQMNEERLKIAIK---DALNENS 187
++ +QS + L+ Q A+A++ + + N E + K DA+
Sbjct: 1327 AKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE 1386
Query: 188 QLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK----VHAEQVLNDKESHIKTLTERLL 243
+L+E++K+L Q + +E V +N + + E +K E ++ D E
Sbjct: 1387 ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 1446
Query: 244 KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDN---PPKGALKK-LIHAAKLNASLKT 299
K +++ +L E + + E+ S + L K A ++ L H K
Sbjct: 1447 KQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1506
Query: 300 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTE----QASLQSENTHFENENQKLQQKLKV 355
L+ E + + QL E K EL + K L+ E Q++L+ E+E K+ +
Sbjct: 1507 LQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLE 1566
Query: 356 MTELYQENEMKLHRK----LTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 411
++ E E KL K + N++ + + +D + E L +K DL E
Sbjct: 1567 FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNE 1626
Query: 412 ------ELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENA--HNRQKLTETE 463
R Q Q+ S + D + +A R +DL++ A R L + E
Sbjct: 1627 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
Query: 464 LK 465
L+
Sbjct: 1687 LE 1688
Score = 60.1 bits (144), Expect = 8e-09
Identities = 92/437 (21%), Positives = 182/437 (41%), Gaps = 75/437 (17%)
Query: 65 EKFSLVQKEYEGYEVES-SLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKEL 123
+K+ Q E E + E+ SL F+ + +SLE E R N L++EI L ++L
Sbjct: 1460 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ETFKRENKNLQEEISDLTEQL 1518
Query: 124 KEE-KSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF-----KIF--QMNEERL 175
E K+ H ++ K + LE E L+S + EA+ + KI Q+ ++
Sbjct: 1519 GEGGKNVH--------ELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Query: 176 KIAIKDALNENSQLQESQKQLLQEA-------------------EVWKEQVSELNKQKVT 216
K I+ L E + E K+ Q V K+ +LN+ ++
Sbjct: 1571 KAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ 1630
Query: 217 FEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYL 276
HA ++ + + +K+L L KD L + + +D+L+ EN A +
Sbjct: 1631 LS----HANRMAAEAQKQVKSLQSLL---KDTQIQLDDAVRANDDLK-------ENIAIV 1676
Query: 277 DNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ 336
+ L A L+ L Q ++ E +E ++ L ++ SL
Sbjct: 1677 ER----------RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1726
Query: 337 SENTHFENENQKLQQKLKVMTELYQENEMKLHRKLT----VEENYRLEKE-----EKLSK 387
++ E++ +LQ +++ + + E K + +T + E + E++ E++ K
Sbjct: 1727 NQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1786
Query: 388 VDEK----ISHATEELETYR-KRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAE 442
E+ + H +E E K K ++LE + +G++ + +K+ ++ R +E
Sbjct: 1787 NMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSE 1846
Query: 443 RNLNDLRKENAHNRQKL 459
R + +L + +++ L
Sbjct: 1847 RRIKELTYQTEEDKKNL 1863
Score = 38.5 bits (88), Expect = 0.024
Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 16/161 (9%)
Query: 79 VESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 138
+E ++KD + E +L+ ++L + LE + LE EL+ E+ +++E + M
Sbjct: 1788 MEQTIKDLQHRLDEAEQIALKGGKKQLQK----LEARVRELEGELEAEQKRNAESVKGMR 1843
Query: 139 DISKRIQSL-----EDESKSLKSQ--VAEAKMTFKIFQMNEERLKIAIKDALNENSQLQE 191
+RI+ L ED+ L+ Q V + ++ K ++ E + L++ ++Q
Sbjct: 1844 KSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQH 1903
Query: 192 SQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 232
+ + A++ + QV++L + + A+Q ++D+E
Sbjct: 1904 ELDEAEERADIAESQVNKLRA-----KSRDIGAKQKMHDEE 1939
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 82.0 bits (201), Expect = 2e-15
Identities = 100/424 (23%), Positives = 199/424 (46%), Gaps = 62/424 (14%)
Query: 78 EVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELM 137
E E KD K + +E E++ R + +L +E L ++L+ E +E +E+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 138 ADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLL 197
A ++ + Q LE+ L+S+V E + +I Q +++++ I+D L E +E +Q L
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD-LEEQLDEEEGARQKL 969
Query: 198 QEAEVWKEQVSELNKQKVTFEDS-KVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDI 256
Q +KVT E K E++L ++ + K + E+ L M+D A +
Sbjct: 970 Q-------------LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKL-MEDRIAECSSQL 1015
Query: 257 TDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDK 316
+++ +++N A + N K+ + + L LK E R E++K
Sbjct: 1016 AEEE-------EKAKNLAKIRN------KQEVMISDLEERLKKEEKTR-------QELEK 1055
Query: 317 TKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVM------TELYQENEMKLHRK 370
K +L +LQ + A LQ++ + + K +++L+ L++ N +K+ R+
Sbjct: 1056 AKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRE 1115
Query: 371 L-----TVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT-----IHSY 420
L ++E++ EK + +K +++ +EELE + +LE+ L+ T + +
Sbjct: 1116 LQAQIAELQEDFESEKASR-NKAEKQKRDLSEELEALK---TELEDTLDTTAAQQELRTK 1171
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLT---ETELKFEL-LEKDPYAL 476
+ Q ++ KKA + +N E + D+R+ +A ++L+ E +F+ LEK+ L
Sbjct: 1172 REQEVAELKKALEE--ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 477 DVPN 480
+ N
Sbjct: 1230 ETDN 1233
Score = 80.9 bits (198), Expect = 4e-15
Identities = 107/475 (22%), Positives = 197/475 (41%), Gaps = 65/475 (13%)
Query: 44 GREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCE 103
G +KL L + K+ E+ L++ + + E L + + +++ E +
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 104 KLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM 163
L + ++ E I LE+ LK+E+ E ++ + L+D+ L++Q+ E K+
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKL 1083
Query: 164 TFKIFQMNEERLKIAI----KDALNENSQLQ----------------ESQKQLLQEAEVW 203
EE L+ A+ + L++N+ L+ ES+K +AE
Sbjct: 1084 Q---LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
Query: 204 KEQVS-ELNKQKVTFEDS--KVHAEQVLNDK------------ESHIKTLTERLLKMKDW 248
K +S EL K ED+ A+Q L K E K ++ M+
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
Query: 249 AAMLGEDITD--DDNLELEMNSE-SENGAYLDNPPKGALKKLIHAAKLNA--SLKTLEGE 303
A E++++ + + N E ++ G DN K++ K + K L+ +
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
Query: 304 RNQIYIQLSEVDKTKEELTEHIKNLQTEQASL-------QSENTHFENENQKLQQKLKVM 356
+++ ++SE D+ + EL E LQ E ++ + + F + L+ +L+
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Query: 357 TELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT 416
EL QE + +KL + R +EEK S +++ EE E RK LE+
Sbjct: 1321 QELLQE---ETRQKLNLSSRIRQLEEEKNSLQEQQ-----EEEEEARK-------NLEKQ 1365
Query: 417 IHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 471
+ + Q Q+ +KK D+ + E L K+ Q+L E L ++ LEK
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK 1420
Score = 73.9 bits (180), Expect = 5e-13
Identities = 117/485 (24%), Positives = 205/485 (42%), Gaps = 43/485 (8%)
Query: 31 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESS--LKDASF 88
WR F V+ L V R+++ L EE K+ EK + V+ E E E + L++ +
Sbjct: 835 WRVFTKVKPLLQVTRQEE---ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI 891
Query: 89 EKEATEAQS-----LEATCEKLNRSNSELEDEILCLEKELKEEKSKH----SEQDELMAD 139
E +A++ E +L ELE+ + LE ++EE+ ++ +E+ ++ A
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 140 ISKRIQSL-EDESKSLKSQVAEAKMTFKIFQMNEERLKIA------IKDALNENSQLQES 192
I + L E+E K Q+ + KI +M EE L + IK+ ++ E
Sbjct: 952 IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 193 QKQLLQEAEVWKEQVSELNKQKVTFEDSKVH---AEQVLNDKESHIKTLTERLLKMKDWA 249
QL +E E K NKQ+V D + E+ + E + L ++D
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1071
Query: 250 AMLGEDITDDDNLELEMNSESENGAYL--DNPPKGALKKLIHAAKLNASLKTLEGERNQI 307
A L I D+ L+L E GA D+ L +L A + L+ +
Sbjct: 1072 AELQAQI-DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Query: 308 YIQLSEVDKTKEELTEHIKNLQTE-------QASLQSENTHFENENQKLQQKLKVMTELY 360
++ +K K +L+E ++ L+TE A+ Q T E E +L++ L+ T+ +
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190
Query: 361 --QENEMKLHRKLTVEE-NYRLEKEEK----LSKVDEKISHATEELETYRKRAKDLEEEL 413
Q +M+ +EE + +LE+ ++ L K + + +EL K + ++ E
Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAES 1250
Query: 414 ERTIHSYQGQIIS-HEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 472
E Q+ H K + + L AE+ + L+ E + L E E K KD
Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGDRLRVELAEK-ASKLQNELDNVSTLLEEAEKKGIKFAKD 1309
Query: 473 PYALD 477
+L+
Sbjct: 1310 AASLE 1314
Score = 73.2 bits (178), Expect = 9e-13
Identities = 107/483 (22%), Positives = 200/483 (41%), Gaps = 89/483 (18%)
Query: 56 LIEEKSKL---LEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSL--EATCEKLNRSNS 110
L E+ SKL L+ S + +E E ++ + AS E + + Q L E T +KLN S+
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
Query: 111 ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQM 170
++L+EEK+ EQ E + K +LE + +L+SQ+A+ K
Sbjct: 1338 I---------RQLEEEKNSLQEQQEEEEEARK---NLEKQVLALQSQLADTKKK------ 1379
Query: 171 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL-----------NKQKVTFED 219
+ D L L+E++K+LL++AE +++ E N+ + +D
Sbjct: 1380 --------VDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDD 1431
Query: 220 SKV---HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYL 276
V H QV ++ E K + L + K +A E+ D E E + L
Sbjct: 1432 LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE---RDRAEAEAREKETKALSL 1488
Query: 277 DNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ 336
+ AL+ + N K L + + +V K EL + + L+ + ++
Sbjct: 1489 ARALEEALEAKEEFERQN---KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
Query: 337 SENTHFENENQKLQQ-KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHA 395
++ E+E Q + KL++ + Q + + R L + EK+ L K ++
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNM-QAMKAQFERDLQTRDEQNEEKKRLLIK---QVREL 1601
Query: 396 TEELETYRKR--------------AKDLEEELE----------RTIHSYQGQIISHEKKA 431
ELE RK+ KDLE ++E + + Q Q+ ++++
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
Query: 432 HDN-------WLAARNAERNLNDLRKENAHNRQKLTETE--LKFELLEKDPYALDVPNTA 482
+ + ++ +E+ L L E +++L +E + E+D A ++ N+A
Sbjct: 1662 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Query: 483 FGR 485
G+
Sbjct: 1722 SGK 1724
Score = 68.9 bits (167), Expect = 2e-11
Identities = 85/411 (20%), Positives = 163/411 (39%), Gaps = 52/411 (12%)
Query: 71 QKEYEGYEVESSLKDASFEKEATEAQS--LEATCEKLNRSNSELEDEILCLEKELKEEKS 128
+KE + + +L++A KE E Q+ L A E L S ++ + LEK + +
Sbjct: 1480 EKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQ 1539
Query: 129 KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIF-----QMNEERLKIAIKDAL 183
+ E + ++ +Q+ ED L+ + K F+ + NEE+ ++ IK
Sbjct: 1540 QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR 1599
Query: 184 NENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLL 243
++L++ +KQ V+ K ++ +D + E ++ IK L +
Sbjct: 1600 ELEAELEDERKQRALA-------VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
Query: 244 KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGE 303
+MKD+ L E D + + ESE LK+LE E
Sbjct: 1653 QMKDYQRELEEARASRDEI-FAQSKESEK-----------------------KLKSLEAE 1688
Query: 304 RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQEN 363
Q+ +L+ ++ + + L E + S + +E ++L+ ++ + E +E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 364 EMKLH------RKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTI 417
+ + RK T++ + + +K +A ++LE K K +ELE +
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 418 HS-YQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 467
S ++ I + E K E L KE A + + TE K +
Sbjct: 1809 KSKFKATISALEAK-------IGQLEEQLEQEAKERAAANKLVRRTEKKLK 1852
Score = 66.6 bits (161), Expect = 8e-11
Identities = 90/444 (20%), Positives = 172/444 (38%), Gaps = 58/444 (13%)
Query: 53 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL 112
+ L E K KLL+ + + E + + + + E L + + S L
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNL 1446
Query: 113 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 172
E + ++ L EEKS + E + E ++ SL + EA + F+
Sbjct: 1447 EKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQN 1506
Query: 173 ERLKIAIKDALNENS-------QLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHA- 224
++L+ ++D ++ +L++S++ L Q+ E + Q+ EL + ED+K+
Sbjct: 1507 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 1566
Query: 225 ------------------EQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEM 266
EQ K IK + E +++D + +E+++
Sbjct: 1567 VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDL 1626
Query: 267 NSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGE-------RNQIYIQLSEVDKTKE 319
+ A ++ K + + KL A +K + E R++I+ Q E +K +
Sbjct: 1627 ---KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLK 1683
Query: 320 ELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRL 379
L I LQ E AS + H E E +L ++ + ++E RL
Sbjct: 1684 SLEAEILQLQEELASSERARRHAEQERDELADEI---------TNSASGKSALLDEKRRL 1734
Query: 380 EKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAAR 439
E +I+ EELE + + L + +T + Q ++ E A + AA+
Sbjct: 1735 E---------ARIAQLEEELEEEQSNMELLNDRFRKT--TLQVDTLNAELAAERS--AAQ 1781
Query: 440 NAERNLNDLRKENAHNRQKLTETE 463
++ L ++N + KL E E
Sbjct: 1782 KSDNARQQLERQNKELKAKLQELE 1805
Score = 31.2 bits (69), Expect = 3.8
Identities = 41/200 (20%), Positives = 75/200 (37%), Gaps = 57/200 (28%)
Query: 54 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK--------------EATEAQSLE 99
S L++EK +L + + +++E E + L + F K E + AQ +
Sbjct: 1725 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD 1784
Query: 100 ATCEKLNRSNSEL----------------------EDEILCLEKELKEEKSKHSEQDELM 137
++L R N EL E +I LE++L++E + + ++L+
Sbjct: 1785 NARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLV 1844
Query: 138 ADISKRIQSL----EDES-----------------KSLKSQVAEAKMTFKIFQMNEERLK 176
K+++ + EDE K LK Q+ EA+ + +L+
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904
Query: 177 IAIKDALNENSQLQESQKQL 196
+ DA N L L
Sbjct: 1905 RELDDATEANEGLSREVSTL 1924
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 80.9 bits (198), Expect = 4e-15
Identities = 77/430 (17%), Positives = 187/430 (43%), Gaps = 34/430 (7%)
Query: 48 KLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNR 107
+L LS + +K K + KE + +E + E+ + L+ + +
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 223
Query: 108 SNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKI 167
SE++ + L+++L+ K +Q +L A+ + L+ S L++QV E ++ ++
Sbjct: 224 EKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRL 282
Query: 168 FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTF---EDSKVHA 224
Q EE++ + ++QE ++++ ++ E +EQ ++ +Q+ E+
Sbjct: 283 NQQQEEKM-------WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 225 EQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGAL 284
E+++ +KE I+ L E++ + E I + + E E E + +
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQ--------EKIREQE----EKRQEEEKIREQEKRQEQEA 383
Query: 285 KKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFEN 344
K K+ + + + + Q ++ + +E++ E + +Q ++ ++ +
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 345 ENQKL---QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELET 401
+ +K+ ++K++ E+ QE E K+ +E E+E K+ + +EK+ E++
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGE----QEGKMCEQEAKMQEQEEKMRRQEEKIRE 499
Query: 402 YRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTE 461
K+ ++ EE++ Q Q E+K + E + + ++ +K+ E
Sbjct: 500 QEKKIREQEEKIREQEEMMQEQ----EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 462 TELKFELLEK 471
E++ E+
Sbjct: 556 QEVRLRQQEE 565
Score = 71.6 bits (174), Expect = 3e-12
Identities = 65/381 (17%), Positives = 169/381 (44%), Gaps = 41/381 (10%)
Query: 56 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEA----QSLEATCEKLNRSNSE 111
L E+ +KL EK LV+ E E++ ++K+ + E + Q L+A + L +
Sbjct: 207 LKEKNAKLQEKLQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 112 LEDEILCLEKELKEEKSKHSEQDELM----ADISKRIQSLEDESKSLKSQVAEAKMTFKI 167
+ ++ +E + + +Q+E M I +R + ++++ + ++ Q + + ++
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 168 FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQV 227
EE+++ + + +++E ++++ ++ ++ +++ ++K+ ++ + E
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 228 LNDKESHIKTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGA 283
+ +E I+ E++ + M++ +GE E EM + E
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE------------ 432
Query: 284 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE 343
K K+ K + + +I Q + + +E++ E + ++A +Q +
Sbjct: 433 -KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 344 NENQKL----------QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIS 393
+ +K+ ++K++ E+ QE E K+ +E E+EEK+ + +EK+
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQEEKMR 547
Query: 394 HATEELETYRKRAKDLEEELE 414
E++ R + EE+++
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQ 568
Score = 61.6 bits (148), Expect = 3e-09
Identities = 75/380 (19%), Positives = 156/380 (41%), Gaps = 41/380 (10%)
Query: 106 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 165
N +N E C E E+K+ H Q+ L ++ ++Q++ + L Q E +M
Sbjct: 80 NGTNPETTTSGGCHSPE-DEQKASHQHQEALRRELEAQVQTI----RILTCQKTELQMAL 134
Query: 166 KIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAE 225
Q ++L+ +D + S+L +S K E E V+ K+ + +
Sbjct: 135 YYSQHAVKQLEGEARDLI---SRLHDSWK-FAGELEQALSAVATQKKKADRYIEELTKER 190
Query: 226 QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK 285
L+ E + T+T+ LK K+ + + + E+++N + LK
Sbjct: 191 DALS-LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE-------------LK 236
Query: 286 KLIHAAKLNASLKTLEGERNQIYIQLSEVDKT------KEELTEHIKNLQTE-----QAS 334
+ + AKL + L+ E + + +L V + EL + Q E +
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 296
Query: 335 LQSENTHFENENQKL---QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK 391
+Q + + +K+ ++K++ E+ E E K+ R +E EKEEK+ +++EK
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR----QEEMMWEKEEKIRELEEK 352
Query: 392 ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 451
+ + E KR ++ + + + ++ E+K + R E + + ++
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 452 NAHNRQKLTETELKFELLEK 471
+K+ E E + + E+
Sbjct: 413 MGEQEEKMWEQEEEMQEQEE 432
Score = 59.7 bits (143), Expect = 1e-08
Identities = 79/406 (19%), Positives = 166/406 (40%), Gaps = 65/406 (16%)
Query: 71 QKEYEGYEVESSLKDA-SFEKEATEAQSLEATCEK-LNRSNSELEDEILCLEKELKEEKS 128
Q E E ++ S L D+ F E +A S AT +K +R EL E L EL
Sbjct: 143 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 202
Query: 129 KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKI-AIKDALNENS 187
E E A + +++Q +E E ++ V E K + ++ + ++ A D L +
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 188 QLQESQKQL-LQEAEVWKEQVSELNKQKVTFEDSKVHA-EQVLNDKESHIKTLTERLLKM 245
Q ++ Q ++E E+W ++++ ++K+ ++ K+ E+ + ++E I+ E++ +
Sbjct: 263 QSVSAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 246 KDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERN 305
+ EM E E + + +
Sbjct: 322 E------------------EMMWEKE--------------------------EKMRRQEE 337
Query: 306 QIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEM 365
++ + ++ + +E++ E K + E+ + E + + Q+ + K+ E +E E
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 366 KLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQII 425
K+ +E E+EEK+ + +EK+ EE++ ++ + EE++
Sbjct: 398 KIRE----QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIR----------- 442
Query: 426 SHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 471
EKK + R E + + ++ K+ E E K + E+
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Score = 53.9 bits (128), Expect = 6e-07
Identities = 58/318 (18%), Positives = 144/318 (45%), Gaps = 33/318 (10%)
Query: 39 SRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSL 98
+RL +E+K+ + E + K+ E+ ++++ E + ++ +EKE
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ---EEMMWEKE------- 329
Query: 99 EATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQV 158
EK+ R + ++ E++++E + K EQ+++ KR Q E + K Q
Sbjct: 330 ----EKMRRQEEMMWEK----EEKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQE 380
Query: 159 AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFE 218
EAKM + ++ E+ KI + +QE ++++ ++ E EQ E+ +Q E
Sbjct: 381 QEAKMWRQEEKIREQEEKIR-----EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ----E 431
Query: 219 DSKVHAEQVLNDKESHIKTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGA 274
+ E+ + ++E I+ E++ + M++ +GE E +M + E
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 275 YLDNPPKGALKKL-IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA 333
+ + KK+ K+ + ++ + +++ Q ++ + +E++ E + ++ ++
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 334 SLQSENTHFENENQKLQQ 351
++ + + +K+Q+
Sbjct: 552 KMREQEVRLRQQEEKMQE 569
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/194 (15%), Positives = 91/194 (46%), Gaps = 13/194 (6%)
Query: 30 LWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE 89
+WR +R + E+K+ + E++ K+ E+ + ++ E + + E
Sbjct: 385 MWRQEEKIREQ-----EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 90 KEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI----Q 145
K + + + EK+ ++++ E+++ E++ K EQ+ M + +++ +
Sbjct: 440 KIREQEKKIREQEEKIREQEEMMQEQ----EEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Query: 146 SLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE 205
+ ++ K ++ Q + + ++ Q EE++ + + ++QE ++++ ++ E +E
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 206 QVSELNKQKVTFED 219
Q L +Q+ ++
Sbjct: 556 QEVRLRQQEEKMQE 569
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 80.9 bits (198), Expect = 4e-15
Identities = 109/461 (23%), Positives = 207/461 (44%), Gaps = 60/461 (13%)
Query: 57 IEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEI 116
++EK++LL+ S +V LKD + +E + QSLE + L+ + ELE++I
Sbjct: 2009 VKEKTELLQTLSS--------DVSELLKDKTHLQE--KLQSLEKDSQALSLTKCELENQI 2058
Query: 117 LCLEKE----LKEEKS---KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQ 169
L KE +KE +S + SE D ++SK +++ E +++ + +
Sbjct: 2059 AQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLR 2118
Query: 170 MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLN 229
E+L++ I+ + + E K+ +E + K++V L ++ E+++
Sbjct: 2119 RGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAE 2178
Query: 230 DKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIH 289
+ ++ ++TL ++ +M + D+ + + SE EN +G L +L
Sbjct: 2179 NSKAEVETLKTQIEEMARSLKVFELDL-------VTLRSEKENLTKQIQEKQGQLSEL-- 2229
Query: 290 AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEH-IKNLQTEQASL-----------QS 337
KL +S K+L E+ Q IQ+ E KT E+ ++ +K L A+L QS
Sbjct: 2230 -DKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288
Query: 338 ENTHFENENQ------KLQQKL-----KVMTELYQENEMKLHRKLTVEENYRLEKEEKLS 386
+ E E+Q KL+ +L K + L Q E + H L LE+E +++
Sbjct: 2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIA 2348
Query: 387 KVDEKISHATEELETYRKRAKDLEEELERTIHSYQG-----QIISHEKKAHDNWLAARNA 441
+ +++ HA E E + + L+ ++E S +G I EK+ N L +
Sbjct: 2349 RTNQE--HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNEL--QKE 2404
Query: 442 ERNLNDLRKENAHNRQKLTETEL-KFELLEKDPYALDVPNT 481
+ +++L N+ L E E K ++ EK A+++ T
Sbjct: 2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQT 2445
Score = 71.6 bits (174), Expect = 3e-12
Identities = 78/415 (18%), Positives = 190/415 (45%), Gaps = 38/415 (9%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 104
+E+ L+ + L EK++LL+ + Y ++SS+ E E + Q LE E+
Sbjct: 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNY--IVLQSSVNGLIQEVEDGK-QKLEKKDEE 2523
Query: 105 LNRSNSELEDEILCLEKELKEE------KSKHSEQDELMADISKRIQSLEDESKSLKSQV 158
++R ++++D+ + K + E K ++ E L ++ ++IQ L+ ++ SL+ +
Sbjct: 2524 ISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTL 2583
Query: 159 AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFE 218
+ ++K + E K+ + + +++ + +L +E ++ +EL +++++ E
Sbjct: 2584 EVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAEL-QEELSGE 2642
Query: 219 DSKVHAE-----QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDN----------LE 263
+++ E + + + +K LT ++K + +D + + L
Sbjct: 2643 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Query: 264 LEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTE 323
L + LD + ++ + KL + + L ++ +++ + +KEEL
Sbjct: 2703 LHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQK----LEIDLLKSSKEELNN 2758
Query: 324 HIK---NLQTEQASLQSENTHFEN----ENQKLQQKLKVMTELYQ--ENEMKLHRKLTVE 374
+K + E + +N + N EN++ Q K+K++ + + E E ++ +K +
Sbjct: 2759 SLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQ 2818
Query: 375 ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 429
EK++ + +D K+ T E++ ++ ++ +E + + Y +ISHEK
Sbjct: 2819 LQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEK 2873
Score = 66.6 bits (161), Expect = 8e-11
Identities = 100/468 (21%), Positives = 200/468 (42%), Gaps = 71/468 (15%)
Query: 59 EKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILC 118
E L K + + G E++ + E E Q + +L NS E+ +
Sbjct: 2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Query: 119 LEKELKEEKSKHSEQDELMA----DISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEER 174
E+E + K K S E++ ++++R+ +L ++ ++ K++ + ++ + +
Sbjct: 2425 KEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Query: 175 LKIAIKDALNENSQLQESQKQLLQEAEVWKEQV----SELNKQKVTFED--------SKV 222
L + +A N LQ S L+QE E K+++ E+++ K +D S+V
Sbjct: 2485 LLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQV 2544
Query: 223 HAEQVL------------NDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSES 270
E L + E I+ L + ++D +L + +N ELE+ ++
Sbjct: 2545 EGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN-ELEL-TKM 2602
Query: 271 ENGAYLDNPPKGALK------KLIHAAKLNASL-KTLEGERN----QIYIQLSEVDKTKE 319
+ ++++ K K ++ A+ A L + L GE+N ++ + L E+ +K+
Sbjct: 2603 DKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKD 2662
Query: 320 ELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQ---ENEMKLHRKLTVEEN 376
+L K L E + L+ + + + K++ YQ K H+ L ++ N
Sbjct: 2663 QL----KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Query: 377 YRLEKE-----EKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKA 431
+ E E EKL+ +E +S E++ + ++L L+ T QI+ KK
Sbjct: 2719 KQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATT-----QILEELKKT 2773
Query: 432 HDNWLAARNAERNLNDLRKEN--AHNRQKL-----TETELKFELLEKD 472
+ L + +N L+KEN A + KL + E + E+L+K+
Sbjct: 2774 KMDNL------KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2815
Score = 62.8 bits (151), Expect = 1e-09
Identities = 86/394 (21%), Positives = 166/394 (42%), Gaps = 66/394 (16%)
Query: 66 KFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKE 125
+ S ++ E E E+ +A E TE LE + N + I+CLE+EL
Sbjct: 1903 ELSRIRSEKASIEHEALYLEADLEVVQTEKLCLE-------KDNENKQKVIVCLEEELSV 1955
Query: 126 EKSKHSEQDELMADISKRIQSLEDESKSLKS----------------QVAEAKMTFKIFQ 169
S+ ++ + +SK+ +L+ S+ +K QVAEA++ K
Sbjct: 1956 VTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTEL 2015
Query: 170 MNEERLKIAIKDALNENSQLQESQKQLLQEAEV-------WKEQVSELNKQKVTFEDSKV 222
+ + L + + L + + LQE + L ++++ + Q+++LNK+K
Sbjct: 2016 L--QTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK-------- 2065
Query: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 282
E ++ + ES L+E + + + L + + L ++S E L
Sbjct: 2066 --ELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR---- 2119
Query: 283 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE-QAS------- 334
KL ++ E ++ I +L E ++ + L + ++NL+ E Q S
Sbjct: 2120 ------GIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELV 2173
Query: 335 -LQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYR---LEKEEKLSKVDE 390
L +EN+ E E K Q ++ M + E+ L + +EN EK+ +LS++D+
Sbjct: 2174 ILDAENSKAEVETLKTQ--IEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDK 2231
Query: 391 KISHATEELETYRKRAKDLEEELERTIHSYQGQI 424
+S LE + ++EE + + Q Q+
Sbjct: 2232 LLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL 2265
Score = 60.5 bits (145), Expect = 6e-09
Identities = 89/485 (18%), Positives = 188/485 (38%), Gaps = 83/485 (17%)
Query: 57 IEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEI 116
I+E L+K ++KE + + + +A+ +K+ + ++ + L R N L +
Sbjct: 20 IQELEGQLDK---LKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEIC 76
Query: 117 LCLEK-------ELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF---- 165
LEK EL+ ++S+ + Q+ + K+I+ LE E K KS++ ++
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSAD 136
Query: 166 ----------KIFQM-----------NEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 204
KIF E LK + E +L+ K L +
Sbjct: 137 VSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQT 196
Query: 205 EQVSELNKQKVTFEDSKVHAEQVLNDKE-SHIKTLTERLLKMKDWAAML--GEDITDDDN 261
+ +N + + + +K SH+ + ++R +D++A GE
Sbjct: 197 LPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSR 256
Query: 262 LELEMNSESENGAYLDNPPKGALKKLIHAA-------------KLNASLKTLEGERNQIY 308
L++ N ++ DN L + A +L K ++G+ N+
Sbjct: 257 STLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQ 316
Query: 309 IQLSEVDKTKEELTEHIKNL------------QTEQAS----------------LQSENT 340
+++K K EL E K L Q +QAS L +
Sbjct: 317 ELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ 376
Query: 341 HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELE 400
+ E+ L+QK+K + +QE + R + ++ + +L++ ++ + L+
Sbjct: 377 NAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436
Query: 401 TYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKEN----AHNR 456
+ ++++LE + ++ ++ E+ + + R++ +++KEN +H+
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 457 QKLTE 461
QK E
Sbjct: 497 QKARE 501
Score = 59.3 bits (142), Expect = 1e-08
Identities = 96/431 (22%), Positives = 167/431 (38%), Gaps = 61/431 (14%)
Query: 48 KLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEAT----EAQSLEATCE 103
K M + E S+ + K ++ E+ + EKE + ++ +A +
Sbjct: 869 KAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQ 928
Query: 104 KLNRSNSELED---EILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAE 160
+L +SN LED E+ L + L EK E +++ + I+ L E+ +LK A
Sbjct: 929 ELKKSNHLLEDSLKELQLLSETLSLEK---KEMSSIISLNKREIEELTQENGTLKEINAS 985
Query: 161 AKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQ----LLQEAEVWKEQVSELNKQKVT 216
E I + S+L + KQ LLQ E +L+++
Sbjct: 986 LNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKA 1045
Query: 217 FEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYL 276
++ E +LN+ S + L ++K+ A ++
Sbjct: 1046 AQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEF-------------------- 1085
Query: 277 DNPPKGALKKLIHAAKLNASLKTLEGERNQ-IYIQLSEVDKT-KEELTEHIKNLQTEQAS 334
L KL A ERNQ + ++L V + + E+T++ N ++E
Sbjct: 1086 -------LTKLAFAE-----------ERNQNLMLELETVQQALRSEMTDNQNNSKSEAGG 1127
Query: 335 LQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISH 394
L+ E + E K+Q K + +L QENE + T E LE E + V E+ S
Sbjct: 1128 LKQEIMTLKEEQNKMQ---KEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERES- 1183
Query: 395 ATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAH 454
E + K DLE + E ++ SY Q++ E + L + +E+ L+ E
Sbjct: 1184 --ERNQCNFKPQMDLEVK-EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQT 1240
Query: 455 NRQKLTETELK 465
R L + L+
Sbjct: 1241 IRGDLETSNLQ 1251
Score = 58.5 bits (140), Expect = 2e-08
Identities = 86/404 (21%), Positives = 169/404 (41%), Gaps = 44/404 (10%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 117
+E S LEK L + E +D S + +E +KL+++ E + +
Sbjct: 547 QENSLTLEKLKLAVADLE------KQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLS 600
Query: 118 CLE------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMN 171
LE +ELKEEK+ S ++ K + +E E ++L+S++ + K Q+
Sbjct: 601 ALELKKKEYEELKEEKTLFSCWK---SENEKLLTQMESEKENLQSKINHLETCLKTQQIK 657
Query: 172 E----ERLKIAIKDALNENSQLQESQKQLLQ---EAEVWKEQVSELNKQKVTFEDSKVHA 224
ER++ D N + +++ L E E K EL +QK F D K H
Sbjct: 658 SHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMEL-QQKAEFSDQK-HQ 715
Query: 225 EQVLNDKESHIKT--LTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN---------- 272
+++ N +KT LT ++ ++ +L +I D D ++++E E+
Sbjct: 716 KEIEN---MCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDA 772
Query: 273 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 332
+ + +L ++ S + GE+ + + SE ++ ++ LQ
Sbjct: 773 SLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRV 832
Query: 333 ASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKI 392
SL+ + N LQ++ + + ++ E E L + + +++ E +++SK+ E
Sbjct: 833 DSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDT 892
Query: 393 SH----ATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAH 432
S E L + K+L + L + + Q +I +K H
Sbjct: 893 SAHQNVVAETLSALENKEKEL-QLLNDKVETEQAEIQELKKSNH 935
Score = 57.4 bits (137), Expect = 5e-08
Identities = 86/426 (20%), Positives = 184/426 (43%), Gaps = 61/426 (14%)
Query: 78 EVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE---DEILCLEKELKEEKSKHSEQD 134
E + S K+++ + + SLE + E + NS+L+ +E++ ++ E++E K +
Sbjct: 817 EADQSPKNSAILQNRVD--SLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMH 874
Query: 135 E-LMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQ 193
+ +A+ S+RI L++++ + ++ VAE T + E+ L++ LN+ + ++++
Sbjct: 875 QSFVAETSQRISKLQEDTSAHQNVVAE---TLSALENKEKELQL-----LNDKVETEQAE 926
Query: 194 KQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERL-LKMKDWAAML 252
+ EL K EDS ++ L+E L L+ K+ ++++
Sbjct: 927 -------------IQELKKSNHLLEDSL-----------KELQLLSETLSLEKKEMSSII 962
Query: 253 GEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLS 312
+ + + L E + E A L+ ++K + S ER + +LS
Sbjct: 963 SLNKREIEELTQENGTLKEINASLNQEKMNLIQK-------SESFANYIDEREKSISELS 1015
Query: 313 EVDKTKEE---LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 369
D+ K+E L + + L + + +N KL+ L T L + + +L +
Sbjct: 1016 --DQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQ 1073
Query: 370 KLTVEENYRLEKEEKLSKV---DEKISHATEELETYRKRAKDLEEELERTIHSYQGQIIS 426
++E + E +E L+K+ +E+ + ELET ++ + + + S G +
Sbjct: 1074 ---LKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQ 1130
Query: 427 HEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGRE 486
+ ++ +NDL +EN K+ +T+ + + LE +P V R
Sbjct: 1131 EIMTLKEE---QNKMQKEVNDLLQEN-EQLMKVMKTKHECQNLESEPIRNSVKERESERN 1186
Query: 487 HSPYGP 492
+ P
Sbjct: 1187 QCNFKP 1192
Score = 50.1 bits (118), Expect = 8e-06
Identities = 88/443 (19%), Positives = 175/443 (39%), Gaps = 54/443 (12%)
Query: 52 MLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSE 111
+L L + +L K + ++ +G+E E + F++ + + + + + ++
Sbjct: 279 LLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNK 338
Query: 112 LEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLEDESKSLKSQVAEAKMTFKI 167
DE++ + + +K++ ++ L D+S + Q+ E SL+ ++ E + K
Sbjct: 339 CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKE---KE 395
Query: 168 FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQV 227
FQ R + + + E Q++ Q LQ+A+ V + K+T V
Sbjct: 396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKN-MHNVLQAELDKLT---------SV 445
Query: 228 LNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKL 287
E++++ ++L + + A I +++ L M + L + + +++
Sbjct: 446 KQQLENNLEEFKQKLCRAEQ--AFQASQIKENE-LRRSMEEMKKENNLLKSHSEQKAREV 502
Query: 288 IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQ 347
H L A LK ++ NQ + E +K ++NT E +
Sbjct: 503 CH---LEAELKNIKQCLNQ-----------SQNFAEEMK----------AKNTSQETMLR 538
Query: 348 KLQQKLKVMTELYQENEMKLHR-KLTVE--ENYRLEKEEKLSKVDEKISHATEELETYRK 404
LQ+K+ QEN + L + KL V E R ++ L K + I ++L K
Sbjct: 539 DLQEKIN-----QQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Query: 405 RAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETEL 464
+K L LE Y+ + EK W + + KEN ++ ET L
Sbjct: 594 ESKALLSALELKKKEYEE--LKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCL 651
Query: 465 KFELLEKDPYALDVPNTAFGREH 487
K + ++ Y V RE+
Sbjct: 652 KTQQIKSHEYNERVRTLEMDREN 674
Score = 47.0 bits (110), Expect = 7e-05
Identities = 91/440 (20%), Positives = 171/440 (38%), Gaps = 41/440 (9%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 104
REK ++ + +EK LL++ YE ++ K A + E E T
Sbjct: 1007 REKSISELSDQYKQEKLILLQRCEETGNAYE--DLSQKYKAAQEKNSKLECLLNECTSLC 1064
Query: 105 LNRSNSELEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLE----DESKSLKS 156
NR N ELE KE +E +K + +E LM ++ Q+L D + KS
Sbjct: 1065 ENRKN-ELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKS 1123
Query: 157 QVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ----EAEVWKEQVSELNK 212
+ K + + +++ + D L EN QL + K + E+E + V E
Sbjct: 1124 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERES 1183
Query: 213 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 272
++ + L KE + + +L++++ AML N EL++ ESE
Sbjct: 1184 ER---NQCNFKPQMDLEVKEISLDSYNAQLVQLE---AML-------RNKELKL-QESEK 1229
Query: 273 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 332
K L+ + + + L+ ++Q L + + EE ++I E
Sbjct: 1230 -------EKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEE--KYISG-PHEL 1279
Query: 333 ASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKI 392
++ Q++N H + Q KL + ++ + + + + +T + R E K+ E++
Sbjct: 1280 STSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEV 1339
Query: 393 SHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKEN 452
E++ + L EL I G+ + H LA + + L +
Sbjct: 1340 GKLLNEVKILNDDSGLLHGELVEDIPG--GEFGEQPNEQHPVSLAPLDESNSYEHLTLSD 1397
Query: 453 AHNRQKLTETELKFELLEKD 472
+ E + KF L+ +
Sbjct: 1398 KEVQMHFAELQEKFLSLQSE 1417
Score = 46.2 bits (108), Expect = 1e-04
Identities = 102/467 (21%), Positives = 179/467 (38%), Gaps = 82/467 (17%)
Query: 81 SSLKDASFEK---EATEAQSLEATCEKLNRSNSELEDEILC--------LEKELKEEKSK 129
SSL D+SF + E T SL + E +N DE+ C KE +K
Sbjct: 1488 SSLGDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAK 1547
Query: 130 HSEQDELMADISKRIQSLEDESKSLKSQVA----EAKMTFKIFQMNEERLKIAIKDALNE 185
E+ E + ++ + QSLE + ++SQ E + ++ + L K L+E
Sbjct: 1548 GVEELESLCEVYR--QSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSE 1605
Query: 186 NSQLQES------------------QKQLLQEAEVWKEQVSELNKQK-----VTFEDSKV 222
N Q Q+ +QL E EV + Q+ L+ + ED+
Sbjct: 1606 NEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAIQ 1665
Query: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSES-----------E 271
+ + + H TER K D + +D D NL++E +E+ E
Sbjct: 1666 GRNESCDISKEHTSETTERTPK-HDVHQICDKDAQQDLNLDIEKITETGAVKPTGECSGE 1724
Query: 272 NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE 331
+ P G K + S + G L +D + E I NLQ
Sbjct: 1725 QSPDTNYEPPGEDKT--QGSSECISELSFSGPN-----ALVPMDFLGNQ--EDIHNLQLR 1775
Query: 332 QASLQSENTH----FENENQKLQQKLKVMTELYQENEMKLHRKLT-VEENYRLEK----- 381
+EN E+ ++K++ L M EL + ++ + +T +E LEK
Sbjct: 1776 VKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGEL 1835
Query: 382 EEKLSKVDEKISHAT-------EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDN 434
+++ S + EK+ + + + +ET DLE +++ G ++ K +D+
Sbjct: 1836 KKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVA---KVNDS 1892
Query: 435 WLAA-RNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
W + E L+ +R E A + E E+++ + L+ N
Sbjct: 1893 WKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDN 1939
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 21/147 (14%)
Query: 280 PKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN 339
P AL+K+ +L L L+ E+ Q QL ++ ++ + ++N +TE
Sbjct: 13 PTRALQKI---QELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTE-------G 62
Query: 340 THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL 399
T+ + ENQ+L + + E ++ + K+ +L V+E+ +E +L+ ++I E+L
Sbjct: 63 TNLKRENQRLME----ICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQI----EKL 114
Query: 400 ETYRKRAKDLEEELERTIHSYQGQIIS 426
E KR K ELER+ + Q +S
Sbjct: 115 EQELKRCK---SELERSQQAAQSADVS 138
Score = 38.5 bits (88), Expect = 0.024
Identities = 72/383 (18%), Positives = 143/383 (37%), Gaps = 64/383 (16%)
Query: 111 ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQM 170
ELE + L+K KE++ + + D L A + K+ Q +E+E + E + +I +
Sbjct: 22 ELEGQ---LDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICES 78
Query: 171 NEE-------RLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVH 223
E+ L++ + QL +KQ+ + + K SEL + + + + V
Sbjct: 79 LEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVS 138
Query: 224 AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGA 283
LN + K T L + ++ ED+ + N E+E
Sbjct: 139 ----LNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVE------------------ 176
Query: 284 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA-----SLQSE 338
+L A +K L Q + +T + T + +++ QA S Q E
Sbjct: 177 -----ERKRLEAEVKAL---------QAKKASQTLPQATMNHRDIARHQASSSVFSWQQE 222
Query: 339 NT--HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIS-HA 395
T H + +Q+ + + + + T++ +++ S D S H
Sbjct: 223 KTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIG---KRDANSSFFDNSSSPHL 279
Query: 396 TEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA-------ERNLNDL 448
++L+ + ++ ELE + ++ ++ K + L A E+ LN
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339
Query: 449 RKENAHNRQKLTETELKFELLEK 471
R E + + K+ LE+
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQ 362
Score = 30.0 bits (66), Expect = 8.5
Identities = 68/330 (20%), Positives = 127/330 (38%), Gaps = 27/330 (8%)
Query: 75 EGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEE--KSKHSE 132
E YE+ + L D+ E + E + LN L D+ L EL E+ + E
Sbjct: 1313 EKYELVTELNDSRSECITATRKMAEEVGKLLNEVKI-LNDDSGLLHGELVEDIPGGEFGE 1371
Query: 133 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQES 192
Q +S + + L E +M F Q L+ K +++ Q+
Sbjct: 1372 QPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSK 1431
Query: 193 QKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAML 252
+L + K + L+ F+ V E L +E + +L+ + + L
Sbjct: 1432 MSELQTYVDSLKAENLVLSTNLRNFQGDLVK-EMQLGLEEGLVPSLSSSCVPDSSSLSSL 1490
Query: 253 GED------ITDDDNLELEMNSE---SENGAYLDNPPKGALKK--LIHAAKLNASLKTLE 301
G+ + ++ L N E S N +D +L++ L +A K +E
Sbjct: 1491 GDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVE 1550
Query: 302 GERNQIYIQLSEVDKTKEELTEH--IKN---------LQTEQASLQSENTHFENENQKLQ 350
+ + ++K +E++ +KN L +E+ L + +EN++ Q
Sbjct: 1551 ELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQ 1610
Query: 351 QKLKVMTELYQENEMKLHRKLTVEENYRLE 380
QKL +T L E+++ +K T + + LE
Sbjct: 1611 QKLTSVT-LEMESKLAAEKKQTEQLSLELE 1639
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 80.5 bits (197), Expect = 6e-15
Identities = 88/427 (20%), Positives = 194/427 (45%), Gaps = 44/427 (10%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 104
+EK+++L+L + E+++K+ + L++ E + + L+ EK ++++L+ + EK
Sbjct: 264 KEKQVSLLLIQITEKENKMKDLTFLLE---ESRDKVNQLE----EKTKLQSENLKQSIEK 316
Query: 105 LNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMT 164
+ ELED + L++ + +K+ E+D +A + + E E++ +S A A +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKAL--EEDLQIATKTICQLTEEKETQMEESNKARAAHS 374
Query: 165 FKI--------------------FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 204
F + + NE++LKI + ++S+L+E K L EV
Sbjct: 375 FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK-LTNNKEVEL 433
Query: 205 EQVSEL--NKQKVTFEDSKVH--AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDD 260
E++ ++ K+ + +E+ + AE++ ++ I L R ++ D L T +
Sbjct: 434 EELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQ 493
Query: 261 NLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD----- 315
E+ L+N + H KL+ K L E + + ++L
Sbjct: 494 YYSKEVKDLKTE---LENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINN 550
Query: 316 --KTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 373
K +E + + I+NLQ + L++E + E ++ + ++K + +EN L +++
Sbjct: 551 NKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVEN 610
Query: 374 EENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 433
+ Y E +++ + +K + +++L Y + LE ELE + +++K+ D
Sbjct: 611 KNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIED 670
Query: 434 NWLAARN 440
++ N
Sbjct: 671 KKISEEN 677
Score = 70.9 bits (172), Expect = 4e-12
Identities = 91/427 (21%), Positives = 184/427 (43%), Gaps = 36/427 (8%)
Query: 57 IEEKSKLLEKFSLVQ-------KEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSN 109
+E KL E + +Q KE E + SL ++ + + L E+
Sbjct: 237 LEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV 296
Query: 110 SELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQ 169
++LE++ + LK+ K + + DI +Q K+L+ + A T I Q
Sbjct: 297 NQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKT--ICQ 354
Query: 170 MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLN 229
+ EE+ +Q++ES K + V V+E + E+ +Q L
Sbjct: 355 LTEEK-----------ETQMEESNKARAAHSFV----VTEFETTVCSLEELLRTEQQRLE 399
Query: 230 DKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELE----MNSESENGAYLDNPPKGALK 285
E +K LT L K + + +T++ +ELE + E E Y + + +
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTK-LTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 286 KLIHA-AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFEN 344
+L +L L+ E E + + IQL+ + +++ ++ +K+L+TE + + +NT +
Sbjct: 459 ELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTS 518
Query: 345 ENQKLQQKLKVMTELYQENEMKLHRKLTVEE-NYRLEKEEKLSKVDEKISHATEELETYR 403
KL + K +T+ + ++M L K E+ N ++EE++ K E + +L R
Sbjct: 519 HCNKLSLENKELTQ--ETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL---R 573
Query: 404 KRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETE 463
+ + EEL++ + ++ E+ ++ N + + +L++EN ++K T
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 464 LKFELLE 470
+ + E
Sbjct: 634 KQLNVYE 640
Score = 57.0 bits (136), Expect = 7e-08
Identities = 88/400 (22%), Positives = 164/400 (41%), Gaps = 42/400 (10%)
Query: 13 ELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQK 72
EL V+G L + + F + L G E++L +L +E L + + +
Sbjct: 432 ELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQELIGLLQAREKEVHDLEIQLTAITT 490
Query: 73 EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELK---EEKSK 129
+ Y E E E + L + C KL+ N EL E + ELK E+ +
Sbjct: 491 SEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINN 550
Query: 130 HSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK--------IFQMNEERLKIAIKD 181
+ +Q+E M K+I++L++ L++++ + K +EE K
Sbjct: 551 NKKQEERML---KQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQ 607
Query: 182 ALNEN---SQLQESQKQLLQEAEVWKEQVS----ELNKQKVTFEDSKVHAEQVLNDKESH 234
N+N +LQ+ K L ++ +Q++ ++NK ++ E +K ++ + +
Sbjct: 608 VENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKE 667
Query: 235 I---KTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENG----AYLDNPPKGALKKL 287
I K E LL+ + A ++ ++ L+ E++ ++ L K K+
Sbjct: 668 IEDKKISEENLLEEVEKAKVIADEAV---KLQKEIDKRCQHKIAEMVALMEKHKHQYDKI 724
Query: 288 IHAAKLNASL-KTLEGERNQIYIQLS-EVDKTKEELTEHIKNLQTEQASLQ------SEN 339
I L K+ E E++ + L E+ K EL K L+ E+ + EN
Sbjct: 725 IEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKEN 784
Query: 340 THF--ENENQKLQQKLKVMTELYQENEMKLHRKLTVEENY 377
T E +++K Q L E+Y + + K TV N+
Sbjct: 785 TATLKEKKDKKTQTFLLETPEIYWKLDSKAVPSQTVSRNF 824
Score = 40.8 bits (94), Expect = 0.005
Identities = 65/267 (24%), Positives = 117/267 (43%), Gaps = 44/267 (16%)
Query: 159 AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFE 218
AE +K+ E R K + L EN ++ E+Q++ +QE + E+VS L ++ E
Sbjct: 113 AEKIKKWKVSTEAELRQK---ESKLQENRKIIEAQRKAIQELQFGNEKVS-LKLEEGIQE 168
Query: 219 DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDN 278
+ + E N+ H+ L +K+ A E + E E Y+D
Sbjct: 169 NKDLIKE---NNATRHLCNL------LKETCARSAE-----KTKKYEYEREETRQVYMD- 213
Query: 279 PPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE----VDKTKEELTEHIKNLQTEQAS 334
++K+I A E R +++ +L E + ++E + I + + + +
Sbjct: 214 -LNNNIEKMITA--FEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSL 270
Query: 335 LQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISH 394
L + T EN K+K +T L +E+ K+++ +EE +L+ E L + EK H
Sbjct: 271 LLIQITEKEN-------KMKDLTFLLEESRDKVNQ---LEEKTKLQ-SENLKQSIEKQHH 319
Query: 395 ATEELETYR-------KRAKDLEEELE 414
T+ELE + K LEE+L+
Sbjct: 320 LTKELEDIKVSLQRSVSTQKALEEDLQ 346
Score = 38.1 bits (87), Expect = 0.031
Identities = 40/181 (22%), Positives = 78/181 (43%), Gaps = 24/181 (13%)
Query: 312 SEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLH--- 368
+E+ + + +L E+ K ++ ++ ++Q E + KL++ ++ +L +EN H
Sbjct: 125 AELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNATRHLCN 184
Query: 369 -------RKLTVEENYRLEKEE------KLSKVDEKISHATEELETYRKRAK-----DLE 410
R + Y E+EE L+ EK+ A EEL + ++ L+
Sbjct: 185 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLK 244
Query: 411 EELERTIH---SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 467
E+ E+ H Y+ +I EK+ + E + DL +R K+ + E K +
Sbjct: 245 EDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTK 304
Query: 468 L 468
L
Sbjct: 305 L 305
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 80.5 bits (197), Expect = 6e-15
Identities = 90/444 (20%), Positives = 180/444 (40%), Gaps = 67/444 (15%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEV----ESSLKDASFEKEATEAQSLEAT 101
EK++A M + K +L K +KE E V E + + EA E
Sbjct: 850 EKEMANMKEEFEKTKEELA-KTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 102 CEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 161
C++L ++ +LE +I KE + +++E+ A+++ + + LEDE LK + +
Sbjct: 909 CDQLIKTKIQLEAKI-------KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
Query: 162 KMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK 221
++T + + + +K+ E + L E+ +++L K+K +++
Sbjct: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDET--------------IAKLTKEKKALQEAH 1007
Query: 222 VHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPK 281
L +E + TLT+ +K+ E DD LE + E E +D
Sbjct: 1008 QQTLDDLQAEEDKVNTLTKAKIKL--------EQQVDD----LEGSLEQEKKIRMD---- 1051
Query: 282 GALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTH 341
L + + LEG+ +++ K++L E +K + E + LQS+
Sbjct: 1052 -----------LERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100
Query: 342 FENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLEKEEKLSKVDEKISHATEE 398
+ +LQ+K+K + +E E ++ + E R + +L ++ E++ A
Sbjct: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
Query: 399 LETYRKRAKDLEEELERTIHSYQGQIISHE------KKAHDNWLA-----ARNAERNLND 447
+ K E E ++ + + HE +K H + +A N +R
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
Query: 448 LRKENAHNRQKLTETELKFELLEK 471
L KE + + ++ + E + K
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSK 1244
Score = 79.3 bits (194), Expect = 1e-14
Identities = 98/437 (22%), Positives = 189/437 (43%), Gaps = 56/437 (12%)
Query: 53 LSGLIEEKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 110
L+ I E K + + ++K E E E++++L++A E E + L E LN+ S
Sbjct: 1516 LTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLE-LNQVKS 1574
Query: 111 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 152
E++ +I ++E+ + K H S Q L A+I R + +E +
Sbjct: 1575 EVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1634
Query: 153 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 212
AEA ++ Q + ++ + DAL L+E + + A + + ++ EL
Sbjct: 1635 HANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1694
Query: 213 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 272
E S+ AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1695 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARN 1754
Query: 273 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 329
+ A K + AA + LK + + +++ K+ L + +K+LQ
Sbjct: 1755 AE------EKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNLEQTVKDLQHRL 1801
Query: 330 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
EQ +L+ + + QKL+ +++ + E E++ +K VE L K E+ K
Sbjct: 1802 DEAEQLALKGG----KKQIQKLEARVREL-----EGEVESEQKRNVEAVKGLRKHERKVK 1852
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 447
++++ TEE R +DL ++L+ + SY+ Q E++++ N R + L
Sbjct: 1853 ---ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHEL-- 1907
Query: 448 LRKENAHNRQKLTETEL 464
E A R + E+++
Sbjct: 1908 ---EEAEERADIAESQV 1921
Score = 67.0 bits (162), Expect = 6e-11
Identities = 89/442 (20%), Positives = 177/442 (40%), Gaps = 53/442 (11%)
Query: 56 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDE 115
L E K KL ++ ++ E + + + + ++ E + L E+ N + + L+ +
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKK 1449
Query: 116 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 175
+K L E K K E +++ + ES+SL +++ FKI EE L
Sbjct: 1450 QRNFDKILAEWKQKCEE-------THAELEASQKESRSLSTEL------FKIKNAYEESL 1496
Query: 176 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 235
++ EN LQ+ L ++ +++ EL K K E K + L + E+ +
Sbjct: 1497 D-QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASL 1555
Query: 236 KTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAA 291
+ ++L+ + + + I + D E++ N + + L I +
Sbjct: 1556 EHEEGKILRIQLELNQVKSEVDRKIAEKDE---EIDQMKRNHIRIVESMQSTLDAEIRSR 1612
Query: 292 KLNASL-KTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFEN---ENQ 347
L K +EG+ N++ IQL+ ++ E ++N + QA L+ H ++ +
Sbjct: 1613 NDAIRLKKKMEGDLNEMEIQLNHANRM---AAEALRNYRNTQAILKDTQLHLDDALRSQE 1669
Query: 348 KLQQKLKVM---TELYQENEMKLHRKLTVEENYRLEKEEKL------------------- 385
L+++L ++ L Q +L L E R E++L
Sbjct: 1670 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729
Query: 386 --SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAER 443
K++ IS E+E + A++ EE+ ++ I + + KK D ++
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAI-TDAAMMAEELKKEQDTSAHLERMKK 1788
Query: 444 NLNDLRKENAHNRQKLTETELK 465
NL K+ H + + LK
Sbjct: 1789 NLEQTVKDLQHRLDEAEQLALK 1810
Score = 60.1 bits (144), Expect = 8e-09
Identities = 79/400 (19%), Positives = 174/400 (43%), Gaps = 54/400 (13%)
Query: 53 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL 112
+ L EE + L E + + KE + +L++A ++ + Q+ E L ++ +L
Sbjct: 979 VKNLTEEMAGLDETIAKLTKE------KKALQEAH-QQTLDDLQAEEDKVNTLTKAKIKL 1031
Query: 113 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKS--QVAEAKMTFKIFQM 170
E ++ LE L++EK + + + ++ ++ + +++ Q + K+ K F+M
Sbjct: 1032 EQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEM 1091
Query: 171 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 230
+ + KI + AL QLQ+ K+L + ++ EL ++ S+ AE+ +D
Sbjct: 1092 SGLQSKIEDEQALG--MQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 231 KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE----------NGAYLDNPP 280
++ ++ERL E+ + ++EMN + E A L +
Sbjct: 1143 LSRELEEISERL-----------EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 281 KGALKKLIHA---AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQS 337
A + HA A+L + L+ + ++ +K K E+ I +L + ++
Sbjct: 1192 TAATLRKKHADSVAELGEQIDNLQRVKQKL-------EKEKSEMKMEIDDLASNMETVSK 1244
Query: 338 ENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEE-NYRLEKEEKLSKVDEK---IS 393
+ E + L+ +L + + +E + +L LT + + E E ++DEK +S
Sbjct: 1245 AKGNLEKMCRALEDQLSEI-KTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVS 1303
Query: 394 HATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 433
+ + + ++ ++L+ +LE I + + + HD
Sbjct: 1304 QLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHD 1343
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/421 (19%), Positives = 170/421 (40%), Gaps = 33/421 (7%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 105
EK + L E K+K E+ L+ + + + ++ E +L + +L
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLIN-DLTAQRARLQTESGEYSRQLDEKDTLVS---QL 1305
Query: 106 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 165
+R +I L+++L+EE S + L ++ + + Q A+A++
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYE--EEQEAKAELQR 1363
Query: 166 KIFQMNEERLKIAIK---DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 222
+ + N E + K DA+ +L+E++K+L Q + +E V +N + + E +K
Sbjct: 1364 AMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQ 1423
Query: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE-SENGAYLDNPPK 281
+ + D ++ + A L + + D + E + E A L+ K
Sbjct: 1424 RLQNEVEDLMIDVE-------RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQK 1476
Query: 282 GALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTH 341
+ L+ L ++ + QL + + + L + I +L TEQ + + H
Sbjct: 1477 -------ESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL-TEQIAEGGKRIH 1528
Query: 342 -FENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELE 400
E ++++Q+ + +E E L + +LE + S+VD KI+ EE++
Sbjct: 1529 ELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1588
Query: 401 TYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLT 460
++ R + S Q + + + +D + E +LN++ + H +
Sbjct: 1589 -------QMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
Query: 461 E 461
E
Sbjct: 1642 E 1642
Score = 31.6 bits (70), Expect = 2.9
Identities = 43/200 (21%), Positives = 81/200 (40%), Gaps = 43/200 (21%)
Query: 54 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE 113
+ LI K KL S +Q E E E+ + +K T+A + +K +++ LE
Sbjct: 1725 TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 114 DEILCLEKELKEEKSKHSEQDEL-MADISKRIQSLEDESKSLKSQVA------------- 159
LE+ +K+ + + E ++L + K+IQ LE + L+ +V
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGL 1844
Query: 160 ---EAKMTFKIFQMNEERLKIA-IKDALNENSQLQESQKQLLQEAE-------------- 201
E K+ +Q E+R I ++D +++ +S K+ +EAE
Sbjct: 1845 RKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQ 1904
Query: 202 -----------VWKEQVSEL 210
+ + QV++L
Sbjct: 1905 HELEEAEERADIAESQVNKL 1924
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 79.7 bits (195), Expect = 9e-15
Identities = 95/482 (19%), Positives = 204/482 (42%), Gaps = 60/482 (12%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 104
+EK+L L E++ +L E+ L ++E + E E EK + + + EK
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQE--------EKMWEQEEKMREQEEK 332
Query: 105 LNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSL-KSQVAEAKM 163
+ R L ++ EK+++E++ K +Q+E M + +R++ E+ + K E KM
Sbjct: 333 MWRQEERLWEQ----EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 164 TFKIFQMNEERLKIAIKDALNENSQLQESQKQLL-QEAEVWKEQVSELNKQKVTFEDSKV 222
EER++ K E ++E ++++ QE +W+++ E +Q++ + K+
Sbjct: 389 ------QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 282
++ + ++E I E K++D M G++ E E E+ +
Sbjct: 443 WEQEKMQEQEEKIWEQEE---KIRDQEEMWGQE---KKMWRQEKMREQEDQMWEQEE--- 493
Query: 283 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHF 342
K+ + + + +++ Q + + +E + E K Q E+ + + T
Sbjct: 494 ---------KMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ- 543
Query: 343 ENENQKLQQKLKVMTE---------LYQENEM--KLHRKLTVEENYRLEKEEKLSKVDEK 391
E E + Q+ K+ E + +E EM + K+ +E E+EEK+ + +EK
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 392 ISHATEEL-----ETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLN 446
+ E++ + + + +D +E E + + ++ E+K + R E +
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
Query: 447 DLRKENAHNRQKLTETELKFE-----LLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSE 501
+ ++ +K+ E E K + + E++ +G+E +G W E
Sbjct: 664 EQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 723
Query: 502 TR 503
R
Sbjct: 724 MR 725
Score = 71.2 bits (173), Expect = 3e-12
Identities = 96/444 (21%), Positives = 198/444 (44%), Gaps = 35/444 (7%)
Query: 47 KKLALMLSGLIEEKSKL---LEKFSLVQKEYEGYEVESSLKDASFEKEATEAQ-SLEATC 102
KK + L +E+ L L + ++ +E + E K E E +E Q +++
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 103 EKLNRSN--------SELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSL 154
KL R+ + L++E+ E+EL+E++ K +Q+E M +R++ E E K +
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLR--EQEGK-M 271
Query: 155 KSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQK 214
+ Q + + K + E+ L+ K+ L E +L+E ++Q+ ++ E EQ ++ +Q
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQ- 329
Query: 215 VTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGA 274
E+ E+ L ++E K + E+ KM+D + E D+ L + E
Sbjct: 330 ---EEKMWRQEERLWEQE---KQMREQEQKMRDQEERMWEQ---DERLREKEERMREQEK 380
Query: 275 YLDNPPKGALKKLIHAA--KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 332
+ K ++ I K+ +T+ + ++ Q E + ++E E + EQ
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKM--QKQEENMWEQEEKEWQQQRLPEQ 438
Query: 333 ASLQSENTHFENENQKL---QQKLKVMTELY-QENEMKLHRKLTVEENYRLEKEEKLSKV 388
E + + +K+ ++K++ E++ QE +M K+ +E+ E+EEK+
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
Query: 389 DEKISHATEELETYRKRAKDLEEEL-ERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 447
++K+ E + +R ++ EE + E+ Q + + EKK + + E + +
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Query: 448 LRKENAHNRQKLTETELKFELLEK 471
+ ++ E E+ E EK
Sbjct: 559 EERMREREKKMREEEEMMREQEEK 582
Score = 60.8 bits (146), Expect = 5e-09
Identities = 77/424 (18%), Positives = 184/424 (43%), Gaps = 58/424 (13%)
Query: 30 LWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE 89
LW + +R + E+K+ + E+ +L EK ++++ + +E E +++
Sbjct: 340 LWEQEKQMREQ-----EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 90 KEAT-----EAQSLEATCEKLNRSNS--------ELEDEILCLEKELKEEKSKHSEQDEL 136
+E E +++ EK+ + E + + L +KE E+ K EQ+E
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 137 MADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDAL---------NENS 187
+ + ++I+ E+ K + KM + QM E+ K+ ++ ++
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 188 QLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKD 247
+L+E ++++ ++ ++W+++ ++ ++K T E K +Q +K + + ER KM++
Sbjct: 515 RLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQ--EEKMREEERMREREKKMRE 571
Query: 248 WAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQI 307
M+ E E +M + E K+ + ++ + ++
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEE--------------------KMWEQEEKMQEQEEKM 611
Query: 308 YIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMK- 366
+ Q ++ + +EE +Q ++ + + + + +K+ ++ + M E QE +M+
Sbjct: 612 WEQEEKMWEQEEE-----DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE--QEEKMRE 664
Query: 367 LHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIIS 426
K+ +E E+EEK+ +EK+ E++ ++ EE++ GQ
Sbjct: 665 QEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724
Query: 427 HEKK 430
EK+
Sbjct: 725 REKE 728
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/373 (17%), Positives = 154/373 (41%), Gaps = 40/373 (10%)
Query: 106 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKR---IQSLEDESKSLKSQVAEAK 162
N +N E C E E+K+ H Q+ L +I + I+ L + L++ + ++
Sbjct: 54 NGTNPETTTSEGCHSPE-DEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQ 112
Query: 163 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQ----VSELNKQKVTFE 218
+ F+ + L+ + ++ L W ++ + EL K++
Sbjct: 113 DAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALS 172
Query: 219 DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDN 278
E + T+T LK K+ + + + E+++N + L
Sbjct: 173 ------------LELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE-----LKR 215
Query: 279 PPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE 338
+ A K L+ + N + + + ++ Q ++ K +E++ + L+ ++ ++ +
Sbjct: 216 KLERA-KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 339 NTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEE 398
+ ++L+++ K + E QE E++ +KL +E E+EEK+ + +EK+ E+
Sbjct: 275 EEKMRRQEKRLREQEKELRE--QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 399 LETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQK 458
+ +R + E+++ E+K D + L + ++E ++K
Sbjct: 333 MWRQEERLWEQEKQMR-----------EQEQKMRDQEERMWEQDERLRE-KEERMREQEK 380
Query: 459 LTETELKFELLEK 471
+ E E K + E+
Sbjct: 381 MWEQEEKMQEEER 393
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 79.7 bits (195), Expect = 9e-15
Identities = 91/443 (20%), Positives = 185/443 (41%), Gaps = 65/443 (14%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 105
EK++A M EE K+ K L + E + E+E + EK + Q ++A E L
Sbjct: 852 EKEMATMK----EEFQKI--KDELAKSEAKRKELEEKMVTLLKEKNDLQLQ-VQAEAEGL 904
Query: 106 NRSNSELEDEI---LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 162
+ + I + LE ++KE + +++E+ A+++ + + LEDE LK + + +
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 163 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 222
+T + + + +K+ E + L E+ +++L K+K +++
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDET--------------IAKLTKEKKALQEAHQ 1010
Query: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 282
L +E + TLT+ +K+ E DD LE + E E +D
Sbjct: 1011 QTLDDLQAEEDKVNTLTKAKIKL--------EQQVDD----LEGSLEQEKKLRMD----- 1053
Query: 283 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHF 342
L + + LEG+ + +++ K++L E +K + E ++LQS+
Sbjct: 1054 ----------LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 343 ENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLEKEEKLSKVDEKISHATEEL 399
+ +LQ+K+K + +E E ++ + E R + +L ++ E++ A
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
Query: 400 ETYRKRAKDLEEELERTIHSYQGQIISHE------KKAHDNWLA-----ARNAERNLNDL 448
+ K E E ++ + + HE +K H + +A N +R L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 449 RKENAHNRQKLTETELKFELLEK 471
KE + + ++ + E + K
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSK 1246
Score = 77.8 bits (190), Expect = 4e-14
Identities = 97/437 (22%), Positives = 188/437 (43%), Gaps = 56/437 (12%)
Query: 53 LSGLIEEKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 110
L+ I E K + + ++K E E E++++L++A E E + L E LN+ S
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLE-LNQVKS 1576
Query: 111 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 152
E++ +I ++E+ + K H S Q L A+I R + +E +
Sbjct: 1577 EVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Query: 153 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 212
AEA ++ Q + +I + DAL L+E + + A + + ++ EL
Sbjct: 1637 HANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1696
Query: 213 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 272
E S+ AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1697 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARN 1756
Query: 273 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 329
+ A K + AA + LK + + +++ K+ + + +K+LQ
Sbjct: 1757 A------EEKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNMEQTVKDLQLRL 1803
Query: 330 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
EQ +L+ + + QKL+ +++ + E E++ +K E L K E+ K
Sbjct: 1804 DEAEQLALKGG----KKQIQKLEARVREL-----EGEVESEQKRNAEAVKGLRKHERRVK 1854
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 447
++++ TEE R +DL ++L+ + SY+ Q E++++ N R + L
Sbjct: 1855 ---ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL-- 1909
Query: 448 LRKENAHNRQKLTETEL 464
E A R + E+++
Sbjct: 1910 ---EEAEERADIAESQV 1923
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/434 (19%), Positives = 168/434 (38%), Gaps = 74/434 (17%)
Query: 89 EKEATEAQ----SLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 144
EKE +E + L + E ++++ LE LE +L E KSK EQ L+ D++ +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 145 QSLE----------DESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQK 194
L+ DE ++L SQ++ K F E LK +++ + + L + +
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFT---QQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 195 QLLQEAEVWKEQVSELNKQKVTF-----------------------------EDSKVHAE 225
+ ++ +EQ E + K E++K
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 226 QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK 285
Q L E H++ + + ++ L ++ D L L++ + A LD + K
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED---LMLDVERTNAACAALDKKQRNFDK 1457
Query: 286 KLIH----AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENT- 340
L + +A L+ + E + +L ++ EE + ++ L+ E +LQ E +
Sbjct: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
Query: 341 -------------HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
E ++++Q+ + +E E L + +LE + S+
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 447
VD KI+ EE++ L+ R + S Q + + + +D + E +LN+
Sbjct: 1578 VDRKIAEKDEEID-------QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNE 1630
Query: 448 LRKENAHNRQKLTE 461
+ + H + E
Sbjct: 1631 MEIQLNHANRMAAE 1644
Score = 65.1 bits (157), Expect = 2e-10
Identities = 79/415 (19%), Positives = 162/415 (39%), Gaps = 21/415 (5%)
Query: 54 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE-ATEAQSLEATCEKLNRSNSEL 112
S IE K +F ++++ E ++ A+ K+ A L + L R +L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 113 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 172
E E ++ E+ + S + ++ K ++LED+ LKS+ E +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 173 ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 232
RL+ + + + + QL + + + +Q+ EL +Q +K L
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
Query: 233 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 292
L E+ + ++ A L ++ + + ++ E A KK K
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK-----K 1398
Query: 293 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 352
L L+ E + + + ++KTK+ L +++L + ++ N ++K +
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQRNF 1455
Query: 353 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 412
K++ E Q+ E + H +L + +L K+ + ++LET ++ K+L++E
Sbjct: 1456 DKILAEWKQKCE-ETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Query: 413 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 467
I QI K+ H+ E+ + +E + L E E E
Sbjct: 1515 ----ISDLTEQIAEGGKRIHE-------LEKIKKQVEQEKCELQAALEEAEASLE 1558
Score = 31.6 bits (70), Expect = 2.9
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 79 VESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 138
+E ++KD + E +L+ +++ + LE + LE E++ E+ +++E + +
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 139 DISKRIQSL-----EDESKSLKSQVAEAKMTFKI--FQMNEERLKIAIKDALNENSQLQE 191
+R++ L ED L+ Q K+ K+ ++ E + L + +LQ
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 192 SQKQLLQEAEVWKEQVSEL 210
++ + A++ + QV++L
Sbjct: 1908 ELEEAEERADIAESQVNKL 1926
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 79.7 bits (195), Expect = 9e-15
Identities = 91/443 (20%), Positives = 185/443 (41%), Gaps = 65/443 (14%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 105
EK++A M EE K+ K L + E + E+E + EK + Q ++A E L
Sbjct: 852 EKEMATMK----EEFQKI--KDELAKSEAKRKELEEKMVTLLKEKNDLQLQ-VQAEAEGL 904
Query: 106 NRSNSELEDEI---LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 162
+ + I + LE ++KE + +++E+ A+++ + + LEDE LK + + +
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 163 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 222
+T + + + +K+ E + L E+ +++L K+K +++
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDET--------------IAKLTKEKKALQEAHQ 1010
Query: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 282
L +E + TLT+ +K+ E DD LE + E E +D
Sbjct: 1011 QTLDDLQAEEDKVNTLTKAKIKL--------EQQVDD----LEGSLEQEKKLRMD----- 1053
Query: 283 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHF 342
L + + LEG+ + +++ K++L E +K + E ++LQS+
Sbjct: 1054 ----------LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 343 ENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLEKEEKLSKVDEKISHATEEL 399
+ +LQ+K+K + +E E ++ + E R + +L ++ E++ A
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
Query: 400 ETYRKRAKDLEEELERTIHSYQGQIISHE------KKAHDNWLA-----ARNAERNLNDL 448
+ K E E ++ + + HE +K H + +A N +R L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 449 RKENAHNRQKLTETELKFELLEK 471
KE + + ++ + E + K
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSK 1246
Score = 77.8 bits (190), Expect = 4e-14
Identities = 97/437 (22%), Positives = 188/437 (43%), Gaps = 56/437 (12%)
Query: 53 LSGLIEEKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 110
L+ I E K + + ++K E E E++++L++A E E + L E LN+ S
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLE-LNQVKS 1576
Query: 111 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 152
E++ +I ++E+ + K H S Q L A+I R + +E +
Sbjct: 1577 EVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Query: 153 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 212
AEA ++ Q + +I + DAL L+E + + A + + ++ EL
Sbjct: 1637 HANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1696
Query: 213 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 272
E S+ AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1697 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARN 1756
Query: 273 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 329
+ A K + AA + LK + + +++ K+ + + +K+LQ
Sbjct: 1757 A------EEKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNMEQTVKDLQLRL 1803
Query: 330 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
EQ +L+ + + QKL+ +++ + E E++ +K E L K E+ K
Sbjct: 1804 DEAEQLALKGG----KKQIQKLEARVREL-----EGEVESEQKRNAEAVKGLRKHERRVK 1854
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 447
++++ TEE R +DL ++L+ + SY+ Q E++++ N R + L
Sbjct: 1855 ---ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL-- 1909
Query: 448 LRKENAHNRQKLTETEL 464
E A R + E+++
Sbjct: 1910 ---EEAEERADIAESQV 1923
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/434 (19%), Positives = 168/434 (38%), Gaps = 74/434 (17%)
Query: 89 EKEATEAQ----SLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 144
EKE +E + L + E ++++ LE LE +L E KSK EQ L+ D++ +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 145 QSLE----------DESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQK 194
L+ DE ++L SQ++ K F E LK +++ + + L + +
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFT---QQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 195 QLLQEAEVWKEQVSELNKQKVTF-----------------------------EDSKVHAE 225
+ ++ +EQ E + K E++K
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 226 QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK 285
Q L E H++ + + ++ L ++ D L L++ + A LD + K
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED---LMLDVERTNAACAALDKKQRNFDK 1457
Query: 286 KLIH----AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENT- 340
L + +A L+ + E + +L ++ EE + ++ L+ E +LQ E +
Sbjct: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
Query: 341 -------------HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
E ++++Q+ + +E E L + +LE + S+
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 447
VD KI+ EE++ L+ R + S Q + + + +D + E +LN+
Sbjct: 1578 VDRKIAEKDEEID-------QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNE 1630
Query: 448 LRKENAHNRQKLTE 461
+ + H + E
Sbjct: 1631 MEIQLNHANRMAAE 1644
Score = 65.1 bits (157), Expect = 2e-10
Identities = 79/415 (19%), Positives = 162/415 (39%), Gaps = 21/415 (5%)
Query: 54 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE-ATEAQSLEATCEKLNRSNSEL 112
S IE K +F ++++ E ++ A+ K+ A L + L R +L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 113 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 172
E E ++ E+ + S + ++ K ++LED+ LKS+ E +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 173 ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 232
RL+ + + + + QL + + + +Q+ EL +Q +K L
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
Query: 233 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 292
L E+ + ++ A L ++ + + ++ E A KK K
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK-----K 1398
Query: 293 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 352
L L+ E + + + ++KTK+ L +++L + ++ N ++K +
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQRNF 1455
Query: 353 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 412
K++ E Q+ E + H +L + +L K+ + ++LET ++ K+L++E
Sbjct: 1456 DKILAEWKQKCE-ETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Query: 413 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 467
I QI K+ H+ E+ + +E + L E E E
Sbjct: 1515 ----ISDLTEQIAEGGKRIHE-------LEKIKKQVEQEKCELQAALEEAEASLE 1558
Score = 31.6 bits (70), Expect = 2.9
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 79 VESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 138
+E ++KD + E +L+ +++ + LE + LE E++ E+ +++E + +
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 139 DISKRIQSL-----EDESKSLKSQVAEAKMTFKI--FQMNEERLKIAIKDALNENSQLQE 191
+R++ L ED L+ Q K+ K+ ++ E + L + +LQ
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 192 SQKQLLQEAEVWKEQVSEL 210
++ + A++ + QV++L
Sbjct: 1908 ELEEAEERADIAESQVNKL 1926
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 79.3 bits (194), Expect = 1e-14
Identities = 97/438 (22%), Positives = 192/438 (43%), Gaps = 46/438 (10%)
Query: 57 IEEKSKLLEKFSLVQKEYEG-YEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDE 115
+E+K K ++ +K Y E +A ++ T+A SL E+ +ELE
Sbjct: 1439 LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERL 1498
Query: 116 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 175
E+++ S + + + ++ K ++LE + + +K+Q+ E + + + + RL
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 176 KIAI--------KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQV 227
++ + +D + Q +E +KQL+++ + ++ + KQ+ ++ E
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMD 1618
Query: 228 LNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKL 287
L D E+HI + K +D E I L+ +M LD+ + L
Sbjct: 1619 LKDLEAHIDSAN----KNRD------EAIKQLRKLQAQMKDCMRE---LDDTRASREEIL 1665
Query: 288 IHAAKLNASLKTLEGERNQIYIQLSEVDKTK-------EELTEHIKNLQTEQASLQSENT 340
A + LK++E E Q+ +L+ ++ K +EL + I N + A E
Sbjct: 1666 AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKR 1725
Query: 341 HFENENQKLQQKLKVM---TELYQENEMKLHRKLT-VEENYRLEKEEKLSKVDEKISHAT 396
E +L+++L+ TEL + K + ++ + + LE+ +K +A
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHA-----QKNENAR 1780
Query: 397 EELETYRKRAKDLEEELERTIHS-YQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 455
++LE K K +E+E T+ S Y+ I + E K A+ E+ N+ ++ A
Sbjct: 1781 QQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKERQAAC 1834
Query: 456 RQ-KLTETELKFELLEKD 472
+Q + TE +LK LL+ D
Sbjct: 1835 KQVRRTEKKLKDVLLQVD 1852
Score = 73.9 bits (180), Expect = 5e-13
Identities = 98/440 (22%), Positives = 199/440 (45%), Gaps = 74/440 (16%)
Query: 31 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK 90
WR F V+ L V R+++ ++ KE E +V K + E
Sbjct: 828 WRLFTKVKPLLQVSRQEE-------------------EMMAKEEELVKVRE--KQLAAEN 866
Query: 91 EATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 150
TE ++L+ S+L E L L+++L+ E +E +EL A ++ + Q LE+
Sbjct: 867 RLTEMETLQ----------SQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
Query: 151 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE-QVSE 209
L+++V E + + Q +++++ I++ L E + +ES +Q LQ +V E ++ +
Sbjct: 917 CHDLEARVEEEEERCQHLQAEKKKMQQNIQE-LEEQLEEEESARQKLQLEKVTTEAKLKK 975
Query: 210 LNKQKVTFEDSK---VHAEQVLNDKESHIKT-LTERLLKMKDWAAMLGEDITDDDNLELE 265
L ++++ ED +++L D+ + T LTE K K A + + +LE
Sbjct: 976 LEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEER 1035
Query: 266 MNSESENGAYLDNPPK-------------GALKKLIHAAK---------LNASLKTLEGE 303
+ E + L+ + L+ I K L A+L +E E
Sbjct: 1036 LRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEE 1095
Query: 304 RNQIYIQLSEVDKTKEELTEHIKNLQTEQAS---LQSENTHFENENQKLQQKLK------ 354
Q + L ++ + + +++E ++L++E+AS + + E + L+ +L+
Sbjct: 1096 AAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDST 1155
Query: 355 -VMTELYQENEMKLH-RKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 412
EL + E +++ K T+EE + E ++ ++ +K S A EEL ++ K ++
Sbjct: 1156 AAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 413 LER---TIHSYQGQIISHEK 429
LE+ T+ + +G++ + K
Sbjct: 1215 LEKAKQTLENERGELANEVK 1234
Score = 72.8 bits (177), Expect = 1e-12
Identities = 75/415 (18%), Positives = 176/415 (42%), Gaps = 59/415 (14%)
Query: 59 EKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILC 118
+ + L ++ + +Q + +++ + K+ + + A + ELE +I
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISE 1115
Query: 119 LEKELKEEKSKHSEQDELMADISKRIQSLEDESK-SLKSQVAEAKMTFKIFQMNEERLKI 177
L+++L+ E++ ++ ++ D+ + +++L+ E + +L S A+ ++ K Q K
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKT 1175
Query: 178 AIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKT 237
++A +Q+QE +++ Q E EQ+ + + K E +K E + + +K
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 238 LTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASL 297
L L+ +SE+
Sbjct: 1236 L-------------------------LQGKGDSEH-----------------------KR 1247
Query: 298 KTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMT 357
K +E + ++ ++ +E ++ + EL + + LQ E ++ + ++++ KL + +
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL- 1306
Query: 358 ELYQENEMKLHRKLTVEEN-YRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT 416
E++++ ++L EEN +L KL +V+++ + E+LE ++ + LE+
Sbjct: 1307 ----ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE----EEEEAKHNLEKQ 1358
Query: 417 IHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 471
I + Q+ +KK D+ AE L+K+ Q+ E ++ LEK
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK 1413
Score = 68.6 bits (166), Expect = 2e-11
Identities = 90/458 (19%), Positives = 185/458 (40%), Gaps = 33/458 (7%)
Query: 43 VGREKKLALMLSGLIEEKSKLLEKF--SLVQKEYEGYEVESSLKDASFEKEATEAQSLEA 100
+ E K+ L G E K K +E L K EG V + L D K E ++
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD-KVTKLQVELDNVTG 1287
Query: 101 TCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAE 160
+ + +S+L + LE +L++ + E++ +S +++ +EDE S + Q+ E
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEE 1347
Query: 161 AKMTFKIFQMNEERLKIAIKDA---LNENSQLQESQKQLLQEAEVWKEQVSELNKQKVT- 216
+ + L + D + ++ E+ +++ ++ + E +S+ +++KV
Sbjct: 1348 EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAA 1407
Query: 217 ---FEDSKVHAEQVLNDK----ESHIKTLTERLLKMKDWAAMLGEDIT-------DDDNL 262
E +K +Q L+D + ++ K K + +L E+ T + D
Sbjct: 1408 YDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA 1467
Query: 263 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELT 322
E E + L + A+++ +LN +T E + +V K+ EL
Sbjct: 1468 EAEAREKETKALSLARALEEAMEQKAELERLNKQFRT---EMEDLMSSKDDVGKSVHELE 1524
Query: 323 EHIKNLQTEQASLQSENTHFENENQKLQQ-KLKVMTELYQENEMKLHRKLTVEENYRLEK 381
+ + L+ + ++++ E+E Q + KL++ L Q + + R L + EK
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL-QAMKAQFERDLQGRDEQSEEK 1583
Query: 382 EEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA 441
+++L + ++ E+ R A ++LE + + I S K + R
Sbjct: 1584 KKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKL 1643
Query: 442 E-------RNLNDLRKENAHNRQKLTETELKFELLEKD 472
+ R L+D R + E E K + +E +
Sbjct: 1644 QAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681
Score = 62.4 bits (150), Expect = 2e-09
Identities = 77/372 (20%), Positives = 154/372 (41%), Gaps = 44/372 (11%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 117
E+K +L+ + ++ E E + S+ A+ +K + + LEA + N++ E ++
Sbjct: 1582 EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLR 1641
Query: 118 CLEKELK----EEKSKHSEQDELMADIS---KRIQSLEDESKSLKSQVAEAKMTFKIFQM 170
L+ ++K E + ++E++A K+++S+E E L+ ++A A+ + Q
Sbjct: 1642 KLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQ 1701
Query: 171 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 230
+ L I ++ + + E +++L EA + E+ L +
Sbjct: 1702 ERDELADEIANSSGKGALALEEKRRL--EARI-------------------AQLEEELEE 1740
Query: 231 KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENG-AYLDNPPKGALKKLIH 289
++ + + + +RL K A + + I D NLE ++EN L+ K KL
Sbjct: 1741 EQGNTELINDRLKK----ANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE 1796
Query: 290 -----AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE-QASLQSENTHFE 343
+K AS+ LE + Q+ QL K ++ + ++ + + + L +
Sbjct: 1797 MEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERR 1856
Query: 344 NENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYR 403
N Q Q K T L Q L R+L E K+ ++ ATE +
Sbjct: 1857 NAEQYKDQADKASTRLKQ-----LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1911
Query: 404 KRAKDLEEELER 415
+ L+ +L R
Sbjct: 1912 REVSSLKNKLRR 1923
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 79.3 bits (194), Expect = 1e-14
Identities = 100/466 (21%), Positives = 207/466 (44%), Gaps = 77/466 (16%)
Query: 38 RSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGY---------EVESSLKDASF 88
++R+ V +E AL L I E+S+ L++ ++EY+ ++E L A
Sbjct: 523 QARMEVSQEDDKALQLLHDIREQSRKLQEIK--EQEYQAQVEEMRLMMNQLEEDLVSARR 580
Query: 89 EKEATEAQSLEA--TCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQS 146
+ E++ E+ E+ R +E + ++L + + K E ++++ +++ A+ +IQ
Sbjct: 581 RSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQE 640
Query: 147 LEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQ 206
L+++ + EA + + +ER + ++ N + +K+L+ EAE +E+
Sbjct: 641 LQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLV-EAEELEEK 699
Query: 207 VSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEM 266
E +V+ + +VH +Q E IK L ++ K D+ D + LE M
Sbjct: 700 HRE---AQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKK----------DLADKETLE-NM 745
Query: 267 NSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD----------- 315
E A+ K +I+A +++ +++LE Q ++LSE +
Sbjct: 746 MQRHEEEAHEKGKILSEQKAMINA--MDSKIRSLE----QRIVELSEANKLAANSSLFTQ 799
Query: 316 ---KTKEELTEHIKN----LQTEQASLQSENTHFENENQK--------------LQQKLK 354
K +EE+ ++ L+T+ L+++N E + +K L+ +L+
Sbjct: 800 RNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLR 859
Query: 355 VMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELE 414
++ ++E +++L R+LT + E+E +L+ + A LE+ ++AK EE
Sbjct: 860 EVSLEHEEQKLELKRQLTELQLSLQERESQLT----ALQAARAALESQLRQAKTELEETT 915
Query: 415 RTIHSYQGQIISHEKKAHDNWLAARNA-------ERNLNDLRKENA 453
+ +H + + A RN+ E LN L ++NA
Sbjct: 916 AEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNA 961
Score = 59.7 bits (143), Expect = 1e-08
Identities = 80/385 (20%), Positives = 167/385 (43%), Gaps = 18/385 (4%)
Query: 50 ALMLSGLIEEKSKLLEKFSLVQKEYEG---YEVESSLKDASFEKEATEAQSLEATCEKLN 106
A + S L + K++L E + ++E + + E K + T LE +L
Sbjct: 898 AALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLT 957
Query: 107 RSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 166
N+EL ++ L K+L E + E +L +++ + + + L SQ +
Sbjct: 958 EDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKT 1017
Query: 167 IFQMNEERLK--IAIKDALNENSQLQESQKQLL-QEAEVWKEQVSELNKQKVTFEDSKVH 223
M EE++ A+ D L E + E+ + +L E ++ +V EL + T + S+
Sbjct: 1018 TCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRAR 1077
Query: 224 AEQVLNDKESHIK-TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 282
A+Q + + ++ + E ++ L E ++L ++N + A L+ +
Sbjct: 1078 ADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARS 1137
Query: 283 ALKKLIHAAKLNASLKTLEGE-RNQIYIQLSEVDKTKEELTEHIKN---LQTEQASL--Q 336
+KL +L L + + + Q+ +Q + + + + L E + L+TE++ L Q
Sbjct: 1138 LQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQ 1197
Query: 337 SENTH--FENENQKLQQKLKVMTELYQENEMKLHRKLTVEE---NYRLEKEEKLSKVDEK 391
EN + +E K++ + T+L + K+ + ++ + R E ++V +
Sbjct: 1198 LENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQ 1257
Query: 392 ISHATEELETYRKRAKDLEEELERT 416
+ LE + R +LEE L++T
Sbjct: 1258 YNELKLALEKEKARCAELEEALQKT 1282
Score = 57.0 bits (136), Expect = 7e-08
Identities = 95/438 (21%), Positives = 182/438 (41%), Gaps = 77/438 (17%)
Query: 57 IEEKSKLLEKFSL-VQKEYEGYE-VESSLKDASFEKEAT----EAQS--LEATCEKLNRS 108
+ E +KL SL Q+ + E + S L+ F E EAQ+ LE EK++
Sbjct: 784 LSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQ 843
Query: 109 NSELEDEILCLEKELKEEKSKHSEQD--------ELMADISKR---IQSLEDESKSLKSQ 157
+ ++ +L LE L+E +H EQ EL + +R + +L+ +L+SQ
Sbjct: 844 DHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQ 903
Query: 158 VAEAKMTFK---------IFQMNEERLKIAIK-DALNEN----SQLQESQKQLLQE-AEV 202
+ +AK + I + R +I K DAL + + L+E QL ++ AE+
Sbjct: 904 LRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAEL 963
Query: 203 ---------WKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLG 253
++ S N + V H + + ++E + + + + +K ML
Sbjct: 964 NNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLE 1023
Query: 254 EDITD-----DDNLELEMNSESENGAYLDNPPK-----GALKKLIHAAK---------LN 294
E + D D+ LE E E+ D + L++++ K +
Sbjct: 1024 EQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRIT 1083
Query: 295 ASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLK 354
S + +E + ++ + + +E ++L + L+ ++ E + LQQKL+
Sbjct: 1084 ESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLE 1143
Query: 355 VMTELYQ---ENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 411
EL Q E + KL +++ +++N+ + ++ + + A + + + DLE
Sbjct: 1144 TERELKQRLLEEQAKLQQQMDLQKNH-------IFRLTQGLQEALDRADLLKTERSDLEY 1196
Query: 412 ELERTIHSYQGQIISHEK 429
+LE Y SHEK
Sbjct: 1197 QLENIQVLY-----SHEK 1209
Score = 55.5 bits (132), Expect = 2e-07
Identities = 102/474 (21%), Positives = 189/474 (39%), Gaps = 104/474 (21%)
Query: 79 VESSLKDASFEKE----ATEAQSLEATCEK-------LNRSNSELEDEILCLEKELKEEK 127
++S K +S EK+ + E Q + C K L+R SE+E + E ELK +
Sbjct: 438 LDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASE 497
Query: 128 SKHS--EQD--------------------ELMADISKRIQSLED---------ESKSLKS 156
++ S EQD E+ + K +Q L D E K +
Sbjct: 498 TQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEY 557
Query: 157 QVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQES--------------QKQLLQEAEV 202
Q +M + Q+ E+ + + L E S+L+ES Q +LL+ +
Sbjct: 558 QAQVEEMRLMMNQLEEDLVSARRRSDLYE-SELRESRLAAEEFKRKATECQHKLLKAKDQ 616
Query: 203 WKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNL 262
K +V E K + K++AEQ L I+ L E+L K + E + +
Sbjct: 617 GKPEVGEYAKLE------KINAEQQLK-----IQELQEKLEKAVKASTEATELLQNIRQA 665
Query: 263 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE-- 320
+ E E ++ +G KKL+ A +L + + + + L + ++ EE
Sbjct: 666 KERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKI 725
Query: 321 --LTEHIKNLQTEQASLQSENTHFENE------------------NQKLQQKLKVMTELY 360
L IK ++ +L++ E E + K++ + + EL
Sbjct: 726 KVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS 785
Query: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
+ N++ + L + N + + EE +S++ ++ + + + + LEE+LE+
Sbjct: 786 EANKLAANSSLFTQRNMKAQ-EEMISELRQQKFYLETQAGKLEAQNRKLEEQLEK----- 839
Query: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTE--TELKFELLEKD 472
ISH+ + N L E L ++ E+ + +L TEL+ L E++
Sbjct: 840 ----ISHQDHSDKNRLL--ELETRLREVSLEHEEQKLELKRQLTELQLSLQERE 887
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 79.0 bits (193), Expect = 2e-14
Identities = 89/445 (20%), Positives = 193/445 (43%), Gaps = 46/445 (10%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 117
EE+ + ++ ++++KE E + E + ++E + + LE + R E + + L
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 118 CLEKEL--KEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 175
E++L K+E+ + +Q+E +R Q E + L+ + E + + EER
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 176 KIAIKDALNENSQLQE--SQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKES 233
+ ++ E + Q+ ++QL +E ++ +EQ +L +++ + ++ EQ L ++
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQ--QLRREQQLRREQQLRREQQLRREQQ 418
Query: 234 HIKTLTERLLKMKDWAAMLGEDITDDDNLELE-------MNSESENGAYLDNPPKGALKK 286
+ R + ++ E + L+ E + E E + K LK+
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 287 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENEN 346
E ER + +++L E ++ +E+ + L+ EQ + + + E
Sbjct: 479 ------------DQEEERRERWLKLEEEER-REQQERREQQLRREQEERREQRLKRQEEE 525
Query: 347 QKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL-----ET 401
++LQQ+L+ +L +E E + + L EE RLE+E + ++ + ++L E
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 402 YRKRAK-DLEEELERTIHSYQGQIISHEKKAHDN--------------WLAARNAERNLN 446
++R K + EE LE+ + + + + E++ + ER
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 447 DLRKENAHNRQKLTETELKFELLEK 471
LR+E R++ + E + E LE+
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQ 670
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/402 (18%), Positives = 169/402 (42%), Gaps = 39/402 (9%)
Query: 89 EKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKH-SEQDELMADISKRIQSL 147
E+E E + E+L + + + DE L +++ +E+ + +E+++L + +
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 148 EDESKSLKSQVAEAK-------------MTFKIFQMNEERLKIAIKDAL-NENSQLQESQ 193
DE + + ++ E + ++FQ EE+ + L E +LQE +
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 194 KQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLG 253
Q +E + +EQ+ +L +Q++ E + +Q +E ++ E
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE------------ 312
Query: 254 EDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE 313
+ + E + E + + L++ + + E ER + ++ +
Sbjct: 313 ----ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 314 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 373
++ +E+ + L+ EQ L+ E + + +Q+L+ +L +E +++ ++L
Sbjct: 369 EEERREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 374 E-ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQII--SHEKK 430
E E R E++ + + ++++ EE + KR EEE ER + Q + E++
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKR----EEETERHEQERRKQQLKRDQEEE 483
Query: 431 AHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 472
+ WL ER R+E R++ E + + E++
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Score = 63.9 bits (154), Expect = 5e-10
Identities = 77/401 (19%), Positives = 170/401 (42%), Gaps = 47/401 (11%)
Query: 65 EKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELK 124
E+ L+++E E ++ + E+E + + E+ R E LE++ +
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE-------LERQYR 1081
Query: 125 EEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALN 184
+E+ E+++L+ + ++ + E E + + + + + + + E+R + ++
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 185 ENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLK 244
E ++Q+ ++QLL+E E K + EL +Q E+ + EQ+L +++ + ER +
Sbjct: 1142 EEEEVQQEEEQLLRE-EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 245 MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNA---SLKTLE 301
++ E+ + Y D + LK K NA + +
Sbjct: 1201 EEE-----------------ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 302 GERNQIYIQLSEV---DKTKEELTEHI------KNLQTEQASLQSENTHFENENQ--KLQ 350
G N+ + QL + D+ ++ +H+ ++ + E+ Q + HF E Q + +
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE 1303
Query: 351 QKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE 410
QK + + E +L R+ E+ R E + K + ++ + E + R++ +D +
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE--QPLRRQERDRK 1361
Query: 411 EELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 451
E H QG+ E++ R ER L++E
Sbjct: 1362 FREEELRHQEQGRKFLEEEQ------RLRRQERERKFLKEE 1396
Score = 56.2 bits (134), Expect = 1e-07
Identities = 85/407 (20%), Positives = 164/407 (40%), Gaps = 48/407 (11%)
Query: 84 KDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKR 143
K A E+ E Q L+ E+L R E E++ +EE+ E+++L+ + ++
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQE-QERQYREEEQLQQEEEQLLREEREK 950
Query: 144 IQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVW 203
+ E E + K + + K + + E+R + + E +LQ+ ++QLL+E E
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE-ERE 1009
Query: 204 KEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE 263
K + E +Q ++ + EQ+L + E + L ER + + + E
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLRE-EREKRRLQERERQYR-------------EEEE 1055
Query: 264 LEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTE 323
L+ E G + + L++ E E Q QL + K E
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRK----------EEELQQEEEQLLREEPEKRRRQE 1105
Query: 324 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEE 383
+ + E+ Q E E +K +++ +L R+ EE + E+E+
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQ-------------ELERQYREEEEVQQEEEQ 1152
Query: 384 KLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAER 443
L + EK +ELE + ++L++E E+ + Q EK+ + R E
Sbjct: 1153 LLREEPEK--RRRQELERQYREEEELQQEEEQLLREEQ------EKRRQERERQYREEEE 1204
Query: 444 NLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGREHSPY 490
RK+ + + ++ + ++E EK+ D GRE+ +
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWE-PEKENAVRDNKVYCKGRENEQF 1250
Score = 54.7 bits (130), Expect = 3e-07
Identities = 89/422 (21%), Positives = 175/422 (41%), Gaps = 50/422 (11%)
Query: 71 QKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELK-EEKSK 129
++E + E E L+ K E Q L+ E+ E + + L E++L+ +E+ +
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQER-EEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Query: 130 HSEQDELMADISKRIQSLEDESKSLKSQ----VAEAKMTFKIFQMNEERLKIAIKDALNE 185
+ EL + +R + LE+E + + Q + + + + ++R + + E
Sbjct: 1502 KFREQELRSQEPER-KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 186 NSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK---VHAEQVLNDKESHIKTLTERL 242
QE ++Q L E +++ L +QKV ++ + + EQ L +E + ER
Sbjct: 1561 EQLRQEREEQQLSRQE--RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 243 LKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK---- 298
K ++ +L E E +++ + + +L+ P+ ++ + + K
Sbjct: 1619 RKFREDEQLLQE------REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 299 ---TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKV 355
EGE Q+ Q E D+ E + ++ + E+ LQ E + Q+L++K +
Sbjct: 1673 EQLLQEGEEQQLRRQ--ERDRKFREEEQQLRRQERERKFLQEEQ---QLRRQELERKFRE 1727
Query: 356 MTELYQENEMKL------HRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDL 409
+L QE E + +RK+ EE R E+EE+ + E+ EE + L
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE--------EQL 1779
Query: 410 EEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELL 469
+E E + Q+ S E ER LR + + + E +L+ E
Sbjct: 1780 RQERE------EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
Query: 470 EK 471
E+
Sbjct: 1834 EQ 1835
Score = 51.6 bits (122), Expect = 3e-06
Identities = 79/442 (17%), Positives = 180/442 (40%), Gaps = 57/442 (12%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 117
EE+ +L ++ ++ E + + ++ ++E + E ++L R E D++L
Sbjct: 523 EEEERLQQR---LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 118 CLEKELKEEKSKHSEQDELMADISKR-IQSLEDESKSLKSQVAEAKMTFKIFQMNEERLK 176
E+E ++++ K +++ L + + ++ LE E + + K + EER +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERR--------EQRLKREEPEEERRQ 631
Query: 177 IAIKDALNENSQLQE--SQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESH 234
+K E + Q+ ++Q +E + +E+ E +Q++ E + EQ L ++E
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ- 690
Query: 235 IKTLTERLL-KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPK--GALKKLIHAA 291
+ ER+ ++ W +LE +++ P K G ++
Sbjct: 691 -EQARERIKSRIPKW------------QWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 292 KLNASLKTLEG-ERNQIYIQLSEVDKTK--------EELTEHIKNLQTEQASLQSENTHF 342
K L+ E + + Q E ++ + EE +E + + + L+ +
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
Query: 343 ENENQKLQQKLKVMTELYQENEMKLHRKLT------VEENYRLEKEEKLSKVDEKISHAT 396
++ Q++ + + E ++ + + R+ +EE +L++ E+ ++ E+
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 397 EELETYRKRAK--------DLEEELERTIHSYQGQIISHEKKAHDNWLAARNAE---RNL 445
E+ E R + + LEEE +R H+ + E+ + L E R
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 446 NDLRKENAHNRQKLTETELKFE 467
+ R+ RQ E +L+ E
Sbjct: 918 REKRRRQEQERQYREEEQLQQE 939
Score = 50.8 bits (120), Expect = 5e-06
Identities = 69/373 (18%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 103 EKLNRSNSELEDEILCLEKELKEEKSKHSEQ---DELMADISKRIQSLEDESKSLKSQVA 159
++L R ++ L E+E + + KH ++ L + +R L+ E ++ + +
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Query: 160 EAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFED 219
K K Q E R + + Q + ++QL +E E +EQ + +++ +
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 220 SKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNP 279
+Q+ ++E E+LLK ++ + E + L+ E + +
Sbjct: 531 RLRSEQQLRREQEER----REQLLKREEEKRL--EQERREQRLKREQEERRDQLLKREEE 584
Query: 280 PKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN 339
+ K +L LK E ER L + ++ ++ L + Q L+SE
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVER------LEQEERREQRLKREEPEEERRQQLLKSE- 637
Query: 340 THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL 399
E E ++ QQ + E ++ + + +E+ + E EE+ + + +
Sbjct: 638 ---EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 400 ETYRKRAKDLEEELERTIHSYQGQIISH------EKKAHDNWLAARNAERNLNDLRKENA 453
E + R + +LE + Q ++ S +++ + R E L +E A
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 454 HNRQKLTETELKF 466
H +Q+ E F
Sbjct: 755 HRQQQEEEQRRDF 767
Score = 48.5 bits (114), Expect = 2e-05
Identities = 95/461 (20%), Positives = 181/461 (39%), Gaps = 63/461 (13%)
Query: 58 EEKSKLLEKFSLVQKEYEG---YEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL-- 112
EE+ E+ L+++E E E+E ++ E + E Q L EK R E
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEE-EVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 113 -EDEILCLEKE--LKEEKSK--------HSEQDELMADISKRIQSLEDESKSLKSQVAEA 161
E+E L E+E L+EE+ K + E++EL K+ ED+ LK Q
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 162 KMTF----KIFQMNEERLKIA-IKDALNENSQLQESQKQLL---------QEAEVWK--- 204
K K++ E + ++D+ + Q Q+ + LL QE W+
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
Query: 205 ------EQVSELNKQKVTFEDSKVHAE-QVLNDKESHIKTLTERLLKMKDWAAMLGE--- 254
EQ+ +++ D K E Q+L ++ + E K ++ +L E
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 255 -----DITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 309
D E E+ + + +L+ + L++ K + L + + +
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQR--LRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 310 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKL-- 367
+ K +EE +Q S Q + F E Q+++++ + L +E +++
Sbjct: 1409 RQDRDRKFREE---------EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 368 HRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE-EELERTIHSYQGQIIS 426
HRK EE E+EE+ E+ EE + R++ +D + E E + + +
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 427 HEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 467
E++ H + + R+E R++ + + + E
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Score = 40.8 bits (94), Expect = 0.005
Identities = 72/390 (18%), Positives = 156/390 (40%), Gaps = 12/390 (3%)
Query: 38 RSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS 97
+ RL +E++L L E+ + E+ K E E S E+E Q
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 98 LEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMAD----ISKRIQSLEDESKS 153
L ++ + E+E LE+ LK E + + EL + +RI+S + +
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 154 LKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQ 213
A+A+ + K++ ++ + E + +ES+ Q +E ++Q E ++
Sbjct: 707 QLESEADARQS-KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Query: 214 KVTF----EDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 269
T+ E+ Q L+ + ++ ER L+ ++ + +++ E
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPP-LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
Query: 270 SENGAYLDN-PPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD-KTKEELTEHIKN 327
E L + L++ A +L L+ ++ + Q D K + +L E K
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 328 LQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
+ + + E Q LQ++ + + +E + ++ E +L++EE+
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTI 417
+E+ +E E ++ K L+++ E+ +
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLL 974
Score = 39.3 bits (90), Expect = 0.014
Identities = 70/338 (20%), Positives = 142/338 (42%), Gaps = 47/338 (13%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLKDASF-EKEATEAQSLEATCEKLNRSNSELEDEI 116
E++ K +E ++++ EG + +D F E E + E + R LE+E
Sbjct: 1592 EQERKFMEDEQQLRRQ-EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 117 LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLK 176
L ++ +E++ +H ++D + + +Q E E + L+ Q + K F+ E++L+
Sbjct: 1651 Q-LRRQEREQQLRH-DRDRKFREEEQLLQ--EGEEQQLRRQERDRK-----FREEEQQLR 1701
Query: 177 IAIKDA--LNENSQL--QESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 232
++ L E QL QE +++ +E ++ +E E +++ + + EQ+ ++E
Sbjct: 1702 RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI-LEEEQLRPERE 1760
Query: 233 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 292
ER K ++ E+ + E ++ S+ + + +
Sbjct: 1761 EQQLRRQERDRKFRE------EEQLRQEREEQQLRSQESDRKFREE-------------- 1800
Query: 293 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 352
+ L ER + ++ + D E ++ + EQ Q + + E Q Q+
Sbjct: 1801 -----EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 353 L--KVMTELYQENEMKLH----RKLTVEENYRLEKEEK 384
+ EL+QE E K RKL E R +KEE+
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 78.6 bits (192), Expect = 2e-14
Identities = 97/488 (19%), Positives = 206/488 (42%), Gaps = 88/488 (18%)
Query: 66 KFSLVQKEYEGYEVESSLK--DASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKEL 123
K L ++ +E+E + D+ + EAQ + EKL R L E L+++L
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502
Query: 124 KEE---------------------KSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 162
+E+ S+ S+ + +A + K+++ LE + K + ++ E
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
Query: 163 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 222
T ++ + + RL++ ++ +S+ ES+ + ++EA + +L + +V E+
Sbjct: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR--QSCQKKLKQMEVQLEEEYE 1620
Query: 223 HAEQVLNDK---ESHIKTLTERLLK------------MKDWAAMLGEDITDDDNLELEMN 267
++VL +K E + TL++++ + +K A+L + D+L+
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
Query: 268 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 327
S+ E A L N + + A K + K +E E +++Q+ ++ K K L E +
Sbjct: 1681 SKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Query: 328 LQTE---------------------------QAS--------LQSENTHFENENQKLQQK 352
LQ E QAS LQ++ E Q+LQ+K
Sbjct: 1737 LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEK 1796
Query: 353 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 412
L+ + +++++ + V+++ +E K+ +++ ++ +++ A L+E
Sbjct: 1797 LQAL-----QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKEN 1851
Query: 413 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 472
+E+ +I + ++ N + +R L D ++E +K E K LE D
Sbjct: 1852 MEKLTEERDQRIAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD 1907
Query: 473 PYALDVPN 480
+L+ N
Sbjct: 1908 LESLEAAN 1915
Score = 56.2 bits (134), Expect = 1e-07
Identities = 94/467 (20%), Positives = 193/467 (41%), Gaps = 54/467 (11%)
Query: 31 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK 90
W+ F +VR + V ++ + EE +L K +KE + S ++ +
Sbjct: 1237 WKLFTTVRPLIEVQLSEE---QIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISE 1293
Query: 91 EATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 150
+E T E ++ E L EKE+KE ++++ +L+ +
Sbjct: 1294 LTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQY--------------DALKKQ 1339
Query: 151 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 210
+ ++ +V EA++ + ++N E D + + + ++ ++E + K+++ +
Sbjct: 1340 MEVMEMEVMEARL-IRAAEINGE------VDDDDAGGEWRLKYERAVREVDFTKKRLQQE 1392
Query: 211 NKQKVTFE-DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELE---- 265
+ K+ E +K E+ L D ++ + L ++K L ++ D L LE
Sbjct: 1393 FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAEL-QDTKLHLEGQQV 1451
Query: 266 MNSESEN-----GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE 320
N E E + L + A ++ + KL L E + QL E D
Sbjct: 1452 RNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAG 1511
Query: 321 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR-----KLTVEE 375
T+ + +L+ E + S+ + E K++++L+ + ++ E +L ++ +
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571
Query: 376 NYRLEKE-EKLSKVDEK-ISHATEELETYR----KRAKDLEEELERTIHSYQGQIISHEK 429
RLE E E++ + K + EE+E R K+ K +E +LE Q + EK
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQK--VLREK 1629
Query: 430 KAHDNWLAARNAERNLND------LRKENAHNRQKLTETELKFELLE 470
+ + LA + + N D LRK+ + L + +L + L+
Sbjct: 1630 RELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK 1676
Score = 55.1 bits (131), Expect = 2e-07
Identities = 78/387 (20%), Positives = 158/387 (40%), Gaps = 45/387 (11%)
Query: 47 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 106
K++ + L E+K K+L E E+E L S + + +S + + L
Sbjct: 1609 KQMEVQLEEEYEDKQKVLR---------EKRELEGKLATLSDQVNRRDFESEKRLRKDLK 1659
Query: 107 RSNSELEDEILCLE---------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQ 157
R+ + L D L L+ +E+ + K++ E + A K +++E E + L Q
Sbjct: 1660 RTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ 1719
Query: 158 V---AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQK 214
+ A+AK EE+L ++ ++L+E Q+ + + + K V++ ++
Sbjct: 1720 IDDIAKAKTAL------EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 215 VTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNL--------ELEM 266
D + E+ +K+ L E+L ++ L + + D + ELE
Sbjct: 1774 AQINDLQAQLEEANKEKQE----LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1829
Query: 267 NSESENGAY-----LDNPPKGALKKLIHAAKLNASLKTLEGERNQ-IYIQLSEVDKTKEE 320
E E L + K ++KL + + E E+N+ + QL + + E
Sbjct: 1830 RLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
Query: 321 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 380
L ++ L+ + E NQ LQ LK+ + + + + ++ +EN L
Sbjct: 1890 LARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLI 1949
Query: 381 KEEKLSKVDEKISHATEELETYRKRAK 407
E S VD ++ + ++++ + K
Sbjct: 1950 NSEGDSDVDSELEDRVDGVKSWLSKNK 1976
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 78.6 bits (192), Expect = 2e-14
Identities = 97/488 (19%), Positives = 206/488 (42%), Gaps = 88/488 (18%)
Query: 66 KFSLVQKEYEGYEVESSLK--DASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKEL 123
K L ++ +E+E + D+ + EAQ + EKL R L E L+++L
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502
Query: 124 KEE---------------------KSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 162
+E+ S+ S+ + +A + K+++ LE + K + ++ E
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
Query: 163 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 222
T ++ + + RL++ ++ +S+ ES+ + ++EA + +L + +V E+
Sbjct: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR--QSCQKKLKQMEVQLEEEYE 1620
Query: 223 HAEQVLNDK---ESHIKTLTERLLK------------MKDWAAMLGEDITDDDNLELEMN 267
++VL +K E + TL++++ + +K A+L + D+L+
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
Query: 268 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 327
S+ E A L N + + A K + K +E E +++Q+ ++ K K L E +
Sbjct: 1681 SKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Query: 328 LQTE---------------------------QAS--------LQSENTHFENENQKLQQK 352
LQ E QAS LQ++ E Q+LQ+K
Sbjct: 1737 LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEK 1796
Query: 353 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 412
L+ + +++++ + V+++ +E K+ +++ ++ +++ A L+E
Sbjct: 1797 LQAL-----QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKEN 1851
Query: 413 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 472
+E+ +I + ++ N + +R L D ++E +K E K LE D
Sbjct: 1852 MEKLTEERDQRIAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD 1907
Query: 473 PYALDVPN 480
+L+ N
Sbjct: 1908 LESLEAAN 1915
Score = 56.2 bits (134), Expect = 1e-07
Identities = 94/467 (20%), Positives = 193/467 (41%), Gaps = 54/467 (11%)
Query: 31 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK 90
W+ F +VR + V ++ + EE +L K +KE + S ++ +
Sbjct: 1237 WKLFTTVRPLIEVQLSEE---QIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISE 1293
Query: 91 EATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 150
+E T E ++ E L EKE+KE ++++ +L+ +
Sbjct: 1294 LTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQY--------------DALKKQ 1339
Query: 151 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 210
+ ++ +V EA++ + ++N E D + + + ++ ++E + K+++ +
Sbjct: 1340 MEVMEMEVMEARL-IRAAEINGE------VDDDDAGGEWRLKYERAVREVDFTKKRLQQE 1392
Query: 211 NKQKVTFE-DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELE---- 265
+ K+ E +K E+ L D ++ + L ++K L ++ D L LE
Sbjct: 1393 FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAEL-QDTKLHLEGQQV 1451
Query: 266 MNSESEN-----GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE 320
N E E + L + A ++ + KL L E + QL E D
Sbjct: 1452 RNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAG 1511
Query: 321 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR-----KLTVEE 375
T+ + +L+ E + S+ + E K++++L+ + ++ E +L ++ +
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571
Query: 376 NYRLEKE-EKLSKVDEK-ISHATEELETYR----KRAKDLEEELERTIHSYQGQIISHEK 429
RLE E E++ + K + EE+E R K+ K +E +LE Q + EK
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQK--VLREK 1629
Query: 430 KAHDNWLAARNAERNLND------LRKENAHNRQKLTETELKFELLE 470
+ + LA + + N D LRK+ + L + +L + L+
Sbjct: 1630 RELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK 1676
Score = 50.1 bits (118), Expect = 8e-06
Identities = 78/390 (20%), Positives = 156/390 (40%), Gaps = 57/390 (14%)
Query: 47 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 106
K++ + L E+K K+L E E+E L S + + +S + + L
Sbjct: 1609 KQMEVQLEEEYEDKQKVLR---------EKRELEGKLATLSDQVNRRDFESEKRLRKDLK 1659
Query: 107 RSNSELEDEILCLE---------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQ 157
R+ + L D L L+ +E+ + K++ E + A K +++E E + L Q
Sbjct: 1660 RTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ 1719
Query: 158 V---AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQK 214
+ A+AK EE+L ++ ++L+E Q+ + + + K V++ ++
Sbjct: 1720 IDDIAKAKTAL------EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 215 VTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNL--------ELEM 266
D + E+ +K+ L E+L ++ L + + D + ELE
Sbjct: 1774 AQINDLQAQLEEANKEKQE----LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1829
Query: 267 NSESENGAY-----LDNPPKGALKKLIHAAKLNASLKTLEGERNQ-IYIQLSEVDKTKEE 320
E E L + K ++KL + + E E+N+ + QL + + E
Sbjct: 1830 RLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
Query: 321 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 380
L ++ L+ + E NQ LQ LK+ + + + + ++ +EN
Sbjct: 1890 LARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDEN---- 1945
Query: 381 KEEKLSKVDEKISHATEELETYRKRAKDLE 410
++ I+ + + Y+KR LE
Sbjct: 1946 --------EDLINSLQDMVTKYQKRKNKLE 1967
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 78.2 bits (191), Expect = 3e-14
Identities = 104/506 (20%), Positives = 213/506 (42%), Gaps = 104/506 (20%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEV-ESSLKDASFEKEATEAQSLEATCEK 104
+ L +L + ++ K+ +L+QK E + E +D + +A E ++ A +
Sbjct: 508 QNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGET--AVLNQ 565
Query: 105 LNRSNSELEDEILCLEKELKEEKSKHSEQDELMAD-----------ISKRIQSLEDESKS 153
L N L++++ L ++LK + H + E + D R+ SLE
Sbjct: 566 LQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNE 625
Query: 154 LKSQVAEAKMTFKIFQMN---EERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 210
L SQ+ E+K K+ Q++ + + ++ + + +Q + Q L +++ EL
Sbjct: 626 LNSQLNESKE--KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQEL 683
Query: 211 NK-----QKVT--FEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDIT--DDDN 261
NK +VT +D + H Q+ ESH+K E+ L ++ L I + D+
Sbjct: 684 NKITTQLDQVTAKLQDKQEHCSQL----ESHLKEYKEKYLSLEQKTEELEGQIKKLEADS 739
Query: 262 LELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERN-QIYIQLSEVDKTKEE 320
LE++ + E AL+ L +LN L+ E + Q+ ++ V T+ +
Sbjct: 740 LEVKASKEQ------------ALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLD 787
Query: 321 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE----LYQENEMKLHRKLTVEEN 376
L + + L+ S++ + T E E Q L+Q + +++ ++E ++ +T +
Sbjct: 788 LQKKSEALE----SIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQK 843
Query: 377 YRLEKE----------EKLSKVDEKISHATEELETYRKRAKDLEEELERT---------- 416
++EKE +KLSKV + + ++ E E ++ K +LE+T
Sbjct: 844 VKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQV 903
Query: 417 -----------------------------IHSYQGQIISHEKKAHDNWLAARNAERNLND 447
++S Q Q+I + N + + N+N+
Sbjct: 904 QMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINE 963
Query: 448 LRKENAHNRQKL--TETELKFELLEK 471
L++ + ++++ + ELK +L+K
Sbjct: 964 LKQSSEQKKKQIEALQGELKIAVLQK 989
Score = 77.8 bits (190), Expect = 4e-14
Identities = 89/449 (19%), Positives = 193/449 (42%), Gaps = 44/449 (9%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSE--LEDE 115
EE K LEK+ +Q++ + + + D+S E ++ E Q EA E N + E +
Sbjct: 107 EELKKELEKYQGLQQQEA--KPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQK 164
Query: 116 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 175
L E+ + KSK+ E+ L +++ L +E + + + K T + + E +
Sbjct: 165 AAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLK-TELLQRPGIEDV 223
Query: 176 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 235
+ K+ + + + + +E+E K++ +L Q + E + L +
Sbjct: 224 AVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEV 283
Query: 236 KTLTERLLKMKDWAAML---GEDITDD------DNLELEMNSESENGAYLDNPPKGALKK 286
+ L K+K L + +T++ D +LE +E N +K
Sbjct: 284 AVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLE-EKHNEESVSKKNIQATLHQK 342
Query: 287 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENEN 346
+ +L + L E ++I+++LSE + ++L E + ++T+ L++E + +
Sbjct: 343 DLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQR 402
Query: 347 QKLQQK-LKVMTELYQ---------------ENEMKLHRKLTVEENYRLEKEEKLSKVDE 390
++ +Q L++ +E+ Q +K R+L+ E+ ++KE++++ +
Sbjct: 403 EEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEK--LMDKEQQVADLQL 460
Query: 391 KISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRK 450
K+S E+L+ + +L+ +L++T +Q Q + R A+ +L + +
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQ----QALQQSTTAKLREAQNDLEQVLR 516
Query: 451 ENAHNRQKLTETEL-------KFELLEKD 472
+ QK+ E LLEK+
Sbjct: 517 QIGDKDQKIQNLEALLQKSKENISLLEKE 545
Score = 74.3 bits (181), Expect = 4e-13
Identities = 90/435 (20%), Positives = 180/435 (41%), Gaps = 44/435 (10%)
Query: 58 EEKSKLLEKFSLVQKEYEGYEVESSLK--DASFEKEATEAQSLEATCEKLNRSNSELEDE 115
E SK + +L QK+ + +++S L + S + E +KL SE+E +
Sbjct: 328 ESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETK 387
Query: 116 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 175
L+ E K+ + + E+++ + I L + + Q+ EA K E+
Sbjct: 388 YQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLK------EQR 441
Query: 176 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 235
+++ + +++ Q+ + Q +L + E KE+V+ + + + +K ++ ++S
Sbjct: 442 QLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTT 501
Query: 236 KTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNA 295
L E ++ +G+ NLE + EN + L+ L A
Sbjct: 502 AKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEK----------EREDLYA 551
Query: 296 SLKTLEGERNQIYIQLSEVDKTKEE----LTEHIKNLQTEQASLQSENTHFENENQKLQQ 351
++ EGE + QL E + T +E LTE +KN Q+E EN H + + QK
Sbjct: 552 KIQAGEGE-TAVLNQLQEKNHTLQEQVTQLTEKLKN-QSESHKQAQENLHDQVQEQKAHL 609
Query: 352 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATE-------------- 397
+ Q+ + L + + E +EK+S++D +I TE
Sbjct: 610 RAA------QDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA 663
Query: 398 ELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQ 457
+L+ + A++ ++ ++ ++ Q+ K D E +L + +++ Q
Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723
Query: 458 KLTETELKFELLEKD 472
K E E + + LE D
Sbjct: 724 KTEELEGQIKKLEAD 738
Score = 71.2 bits (173), Expect = 3e-12
Identities = 91/447 (20%), Positives = 183/447 (40%), Gaps = 67/447 (14%)
Query: 59 EKSKLLEKFSLVQKEYEGYEVESSLKDAS--FEKEATEAQS----LEATCEKLNRSNSEL 112
EK L+ + S V+ + +V SLK++ FEKE + ++ LE TC++L
Sbjct: 847 EKEALMTELSTVKDKLS--KVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ 904
Query: 113 EDEILCLEKELKEEKSKHSE-----------QDELMADISKRIQSLEDESKSLKSQVAEA 161
+ L +KELK+ K E E + ++ E E + L+ + E
Sbjct: 905 MENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINEL 964
Query: 162 KMTF----KIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTF 217
K + K + + LKIA+ ++LQ+ Q QE KE++S L +
Sbjct: 965 KQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN---Y 1021
Query: 218 EDSKVHAEQVLND---KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGA 274
E S+ +Q+ +D +ES + + L +++ ++ ED+ + N
Sbjct: 1022 EKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRN------------- 1068
Query: 275 YLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQ-----LSEVDKTKEELTEHIKNLQ 329
G KLI K + + + + +Q L ++ K K + + N +
Sbjct: 1069 -----QIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK 1123
Query: 330 TEQASLQSENTHFENENQKLQQKLKV--MTELYQENEMKLHRKLTVEENYRLEKEEKLSK 387
++ A ++ E E KL ++LK + + + +K ++L +++ +LE + K
Sbjct: 1124 SKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQ--KLELQGKADS 1181
Query: 388 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIIS-----------HEKKAHDNWL 436
+ + + + + K EEEL++ + ++ S HE+ +
Sbjct: 1182 LKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTM 1241
Query: 437 AARNAERNLNDLRKENAHNRQKLTETE 463
NL ++KE ++++++E E
Sbjct: 1242 QITALNENLGTVKKEWQSSQRRVSELE 1268
Score = 70.1 bits (170), Expect = 7e-12
Identities = 96/478 (20%), Positives = 203/478 (42%), Gaps = 60/478 (12%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 105
E++L L E++ EK +++ +++ S + +++ T + L+ +K
Sbjct: 427 ERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKT 486
Query: 106 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 165
+ + E + +L+E ++ + + D ++IQ+LE + + ++K
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLE-------ALLQKSKENI 539
Query: 166 KIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAE 225
+ + E L I+ E + L QL ++ +EQV++L ++ +S A+
Sbjct: 540 SLLEKEREDLYAKIQAGEGETAVL----NQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQ 595
Query: 226 QVLND----KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPK 281
+ L+D +++H++ +R+L ++ T + L ++N E + LD K
Sbjct: 596 ENLHDQVQEQKAHLRAAQDRVLSLE----------TSVNELNSQLNESKEKVSQLDIQIK 645
Query: 282 GALKKLIHA--------AKLNASLKTLEG-------ERNQIYIQLSEV-----DKTK--E 319
+ L+ A A L L T + E N+I QL +V DK +
Sbjct: 646 AKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCS 705
Query: 320 ELTEHIKNLQTEQASLQSENTHFENENQKLQ--------QKLKVMTELYQENEMKLHRKL 371
+L H+K + + SL+ + E + +KL+ K + + +L Q+ ++ +L
Sbjct: 706 QLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLEL 765
Query: 372 TVEE-NYRLEKEEKL-SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 429
E + +LE E+++ S + +E LE+ +++ EE E+ I + +S E
Sbjct: 766 RATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEE--EKQILKQDFETLSQET 823
Query: 430 KAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGREH 487
K L R + + +L+K +TE + L K +L + F +E+
Sbjct: 824 KIQHEELNNR-IQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKEN 880
Score = 65.1 bits (157), Expect = 2e-10
Identities = 97/437 (22%), Positives = 175/437 (40%), Gaps = 55/437 (12%)
Query: 45 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 104
+++ + + S L E K K L SL QK E L+ S E +A++ Q+L+ ++
Sbjct: 700 KQEHCSQLESHLKEYKEKYL---SLEQKTEELEGQIKKLEADSLEVKASKEQALQ-DLQQ 755
Query: 105 LNRSNSELEDEILCLEKELKEEKSKHS-------EQDELMADISKRIQSLEDESKSLKSQ 157
+ N++LE L K+L+ EK S ++ E + I +++ E+E + LK
Sbjct: 756 QRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQD 815
Query: 158 VAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSE----LNKQ 213
KI E L I+ + E +++ ++ L+ E K+++S+ L
Sbjct: 816 FETLSQETKI---QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNS 872
Query: 214 KVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENG 273
K FE + + D E K L +L + + + L+ + E E
Sbjct: 873 KSEFEKENQKGKAAILDLEKTCKELKHQL------QVQMENTLKEQKELKKSLEKEKEAS 926
Query: 274 AYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA 333
L ++LI A +LK E E Q+ ++E+ ++ E+ + I+ LQ E
Sbjct: 927 HQLKLELNSMQEQLIQAQN---TLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELK 983
Query: 334 SLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIS 393
+ T EN KL ++LT ++EK+S +
Sbjct: 984 IAVLQKTELEN---------------------KLQQQLTQAAQELAAEKEKISVLQNNYE 1022
Query: 394 HATEELETYRKRAKDLEEELERTIHSYQGQIISHEKK---AHDNWLAARNAERNLNDLRK 450
+ E + + E EL T + + S E+K A ++ ++ RN N N L +
Sbjct: 1023 KSQETFKQLQSDFYGRESELLAT----RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQ 1078
Query: 451 ENAHNRQKLTETELKFE 467
E + L + K E
Sbjct: 1079 ELKTAKATLEQDSAKKE 1095
Score = 62.4 bits (150), Expect = 2e-09
Identities = 75/309 (24%), Positives = 145/309 (46%), Gaps = 23/309 (7%)
Query: 46 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 105
E+KL+L LI ++++ + L+Q E +++L+ S +KE Q L+ C+ L
Sbjct: 1053 EEKLSLAQEDLISNRNQIGNQNKLIQ---ELKTAKATLEQDSAKKE----QQLQERCKAL 1105
Query: 106 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 165
+++ E EKEL EKSK +E +E+ K I L +E KS K + +
Sbjct: 1106 Q----DIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNL 1161
Query: 166 KIFQ--MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVH 223
K + + +++L++ K + + QE + Q + + +V KE+ EL K+ + +++K+H
Sbjct: 1162 KDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE-EELKKEFIE-KEAKLH 1219
Query: 224 AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGA 283
+E + +KE +K E K+ L E++ ++ E S + L+
Sbjct: 1220 SE--IKEKEVGMKKHEENEAKLTMQITALNENL---GTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 284 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE 343
++ A L A+++ + ER + + + + E+L + LQ + + +
Sbjct: 1275 RGEI---AVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELG 1331
Query: 344 NENQKLQQK 352
ENQ LQ K
Sbjct: 1332 RENQSLQIK 1340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,202,338
Number of Sequences: 37866
Number of extensions: 2512508
Number of successful extensions: 28048
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 515
Number of HSP's successfully gapped in prelim test: 1844
Number of HSP's that attempted gapping in prelim test: 12097
Number of HSP's gapped (non-prelim): 9407
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.