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Search of human proteins with 42740899
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
(761 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 1537 0.0
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 1516 0.0
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 1474 0.0
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 1459 0.0
gi|56847634 hypothetical protein LOC441294 [Homo sapiens] 1215 0.0
gi|146262005 CTAGE family, member 6 [Homo sapiens] 1211 0.0
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 1205 0.0
gi|193290160 CTAGE family, member 4 [Homo sapiens] 1202 0.0
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 1201 0.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 282 7e-76
gi|118498356 kinectin 1 isoform a [Homo sapiens] 98 2e-20
gi|118498368 kinectin 1 isoform c [Homo sapiens] 98 2e-20
gi|33620775 kinectin 1 isoform a [Homo sapiens] 98 2e-20
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 85 2e-16
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 85 2e-16
gi|156104908 myosin heavy chain 6 [Homo sapiens] 85 2e-16
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 82 2e-15
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 81 4e-15
gi|55770834 centromere protein F [Homo sapiens] 81 4e-15
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 80 5e-15
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 80 5e-15
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 80 9e-15
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 80 9e-15
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 79 1e-14
gi|32698688 citron [Homo sapiens] 79 1e-14
gi|148746195 trichohyalin [Homo sapiens] 79 2e-14
gi|42794779 myosin 18A isoform b [Homo sapiens] 79 2e-14
gi|28416946 myosin 18A isoform a [Homo sapiens] 79 2e-14
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 78 3e-14
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 78 3e-14
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 1537 bits (3979), Expect = 0.0
Identities = 761/761 (100%), Positives = 761/761 (100%)
Query: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW
Sbjct: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
Query: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE
Sbjct: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
Query: 121 ATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
ATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES
Sbjct: 121 ATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
Query: 181 KSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELN 240
KSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELN
Sbjct: 181 KSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELN 240
Query: 241 KQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE 300
KQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE
Sbjct: 241 KQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE 300
Query: 301 NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE 360
NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE
Sbjct: 301 NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE 360
Query: 361 QASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK 420
QASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK
Sbjct: 361 QASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK 420
Query: 421 ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 480
ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE
Sbjct: 421 ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 480
Query: 481 NAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPLDHQITNERGESSCDRLT 540
NAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPLDHQITNERGESSCDRLT
Sbjct: 481 NAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPLDHQITNERGESSCDRLT 540
Query: 541 DPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSF 600
DPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSF
Sbjct: 541 DPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSF 600
Query: 601 NMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPL 660
NMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPL
Sbjct: 601 NMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPL 660
Query: 661 FPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYL 720
FPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYL
Sbjct: 661 FPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYL 720
Query: 721 PPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 761
PPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
Sbjct: 721 PPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 761
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 1516 bits (3925), Expect = 0.0
Identities = 761/804 (94%), Positives = 761/804 (94%), Gaps = 43/804 (5%)
Query: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW
Sbjct: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
Query: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE
Sbjct: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
Query: 121 ATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
ATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES
Sbjct: 121 ATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
Query: 181 KSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELN 240
KSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELN
Sbjct: 181 KSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELN 240
Query: 241 KQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE 300
KQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE
Sbjct: 241 KQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE 300
Query: 301 NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE 360
NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE
Sbjct: 301 NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE 360
Query: 361 QASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK 420
QASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK
Sbjct: 361 QASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK 420
Query: 421 ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 480
ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE
Sbjct: 421 ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 480
Query: 481 NAHNRQKLTETELKFELLEKDPYALDVPNTAF---------------------------- 512
NAHNRQKLTETELKFELLEKDPYALDVPNTAF
Sbjct: 481 NAHNRQKLTETELKFELLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTL 540
Query: 513 ---------------GRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWD 557
GRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWD
Sbjct: 541 LEGPLRLSPLLPGGGGRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWD 600
Query: 558 QDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEME 617
QDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEME
Sbjct: 601 QDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEME 660
Query: 618 SSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFP 677
SSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFP
Sbjct: 661 SSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFP 720
Query: 678 PPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRS 737
PPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRS
Sbjct: 721 PPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRS 780
Query: 738 EFPSGLIPPSNEPATEHPEPQQET 761
EFPSGLIPPSNEPATEHPEPQQET
Sbjct: 781 EFPSGLIPPSNEPATEHPEPQQET 804
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 1474 bits (3816), Expect = 0.0
Identities = 740/783 (94%), Positives = 740/783 (94%), Gaps = 43/783 (5%)
Query: 22 VVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALM 81
VVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALM
Sbjct: 10 VVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALM 69
Query: 82 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL 141
LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL
Sbjct: 70 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL 129
Query: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 201
EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE
Sbjct: 130 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 189
Query: 202 ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 261
ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE
Sbjct: 190 ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 249
Query: 262 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 321
SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK
Sbjct: 250 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 309
Query: 322 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 381
LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK
Sbjct: 310 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 369
Query: 382 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 441
LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE
Sbjct: 370 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 429
Query: 442 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD
Sbjct: 430 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 489
Query: 502 PYALDVPNTAF-------------------------------------------GRGSRG 518
PYALDVPNTAF GRGSRG
Sbjct: 490 PYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRG 549
Query: 519 PGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPP 578
PGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPP
Sbjct: 550 PGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPP 609
Query: 579 QRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLP 638
QRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLP
Sbjct: 610 QRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLP 669
Query: 639 AENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFP 698
AENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFP
Sbjct: 670 AENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFP 729
Query: 699 GPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQ 758
GPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQ
Sbjct: 730 GPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQ 789
Query: 759 QET 761
QET
Sbjct: 790 QET 792
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 1459 bits (3778), Expect = 0.0
Identities = 732/775 (94%), Positives = 732/775 (94%), Gaps = 43/775 (5%)
Query: 30 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 89
MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK
Sbjct: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
Query: 90 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 149
SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE
Sbjct: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
Query: 150 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 209
KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK
Sbjct: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
Query: 210 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 269
DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE
Sbjct: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
Query: 270 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 329
RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
Query: 330 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 389
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY
Sbjct: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
Query: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY
Sbjct: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
Query: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN
Sbjct: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
Query: 510 TAF-------------------------------------------GRGSRGPGNPLDHQ 526
TAF GRGSRGPGNPLDHQ
Sbjct: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
Query: 527 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 586
ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS
Sbjct: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
Query: 587 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 646
NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP
Sbjct: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
Query: 647 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 706
GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA
Sbjct: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
Query: 707 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 761
MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
Sbjct: 721 MRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET 775
>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
Length = 777
Score = 1215 bits (3143), Expect = 0.0
Identities = 618/775 (79%), Positives = 663/775 (85%), Gaps = 45/775 (5%)
Query: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
MEEPG TPQPYLGL+LEELRRVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
A E A+SLEATCEKLNRSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK QVSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
Query: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLELE+NS+
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
ENGA LD+P KGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
T+QASLQSEN +FE+ENQKLQQKLK+MTE YQENEMKL+RKLTVEENYR+E+EEKLS+V+
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
EK+S ATE+LETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAF-------------------------- 512
KENAHN+QKLTETELKFELLEKDP ALDV NTAF
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
Query: 513 -----------------GRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 555
GRG RGPGNPLDHQITNERGE SCDRLTDPHRAPSDTGSLS P
Sbjct: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
Query: 556 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 615
+QD +MMFPPPGQSYPDSALPPQR+DRF SNS RLSG AE RSF M SLDKMDGSMPSE
Sbjct: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
Query: 616 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 675
MESSRND KDDLGNLNVPDSSLPAENEATGPGF+PPPLAP+RGPLFPVD RGPF+RRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
Query: 676 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 730
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPY PRPGF+P P
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNP 775
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 1211 bits (3133), Expect = 0.0
Identities = 616/775 (79%), Positives = 662/775 (85%), Gaps = 45/775 (5%)
Query: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
MEEPG TPQPYLGL+LEELRRVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
A E A+SLEATCEKLNRSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK +VSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
Query: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLELE+NS+
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
ENGA LD+P KGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
T+Q SLQSEN +FE+ENQKLQQKLK+MTE YQE+EMKL+RKLTVEENYR+E+EEKLSKV+
Sbjct: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
Query: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
EK+S ATE+LETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAF-------------------------- 512
KENAHN+QKLTETELKFELLEKDP ALDV NTAF
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
Query: 513 -----------------GRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 555
GRG RGPGNPLDHQITNERGE SCDRLTDPHRAPSDTGSLS P
Sbjct: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
Query: 556 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 615
+QD +MMFPPPGQSYPDSALPPQR+DRF SNS RLSG AE RSF M SLDKMDGSMPSE
Sbjct: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
Query: 616 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 675
MESSRND KDDLGNLNVPDSSLPAENEATGPGF+PPPLAP+RGPLFPVD RGPF+RRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
Query: 676 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 730
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPY PRPGF+P P
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNP 775
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 1205 bits (3117), Expect = 0.0
Identities = 617/775 (79%), Positives = 660/775 (85%), Gaps = 45/775 (5%)
Query: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
MEEPG TPQPYLGL+LEEL RVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
A E A+SLEATCEKL+RSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK QVSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
Query: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLEL++NS+
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
Query: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
ENGA LD+PPKGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
T+QASLQSEN +FE+ENQKLQQKLK+MTE YQENEMKL+RKLTVEENYR+E+EEKLS+V+
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
EKISHATEELETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAFGR------------------------ 514
KENAHN+QKLTE ELKFELLEKDP ALDV NTAFGR
Sbjct: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
Query: 515 ----------------GSRG---PGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 555
G RG PGNPLDHQITNERGE S DRL DPHRAPSDTGSLS P
Sbjct: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
Query: 556 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 615
+QDRRMMFPPPGQSYPDS LPPQR+DRF SNS RLSGPAE RSF M SLDKMD SMPSE
Sbjct: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
Query: 616 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 675
MESSRND KDDLGNLNVPDSSLPAENEATGPG +PPPLAPI GPLFPVD RGPF+RRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
Query: 676 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 730
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNP 775
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 1202 bits (3111), Expect = 0.0
Identities = 617/775 (79%), Positives = 659/775 (85%), Gaps = 45/775 (5%)
Query: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
MEEPG TPQPYLGL+LEELRRVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
A E A+SLEATCEKLNRSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK +VSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
Query: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLELE+NS+
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
ENGA LD+P KGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
T+QASLQSEN +FE+ENQKLQQKLK+MTE YQENEMKL+RKLTVEENYR+E+EEKLS+V+
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
EKIS ATE LETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 421 EKISRATEGLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAFGR------------------------ 514
KENAHN+QKLTETELKFELLEKDP ALDV NTAFGR
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
Query: 515 ----------------GSRG---PGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 555
G RG PGNPLDHQITNERGE S DRL DPHRAPSDTGSLS P
Sbjct: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
Query: 556 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 615
+QDRRMMFPPPGQSYPDS LPPQR+DRF SNS RLSGPAE RSF M SLDKMD SMPSE
Sbjct: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
Query: 616 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 675
MESSRND KDDLGNLNVPDSSLPAENEATGPG +PPPLAPI GPLFPVD RGPF+RRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
Query: 676 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 730
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNP 775
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 1201 bits (3107), Expect = 0.0
Identities = 621/745 (83%), Positives = 642/745 (86%), Gaps = 45/745 (6%)
Query: 30 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 89
MRPDS+ YGFPWELVI AAV GFFAVLF LWRSFRSV SRLYV REKK A+ LSGLIEEK
Sbjct: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
Query: 90 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 149
KLLEKFSLVQKEYEGYEVESSLK+ASFEKEATEAQSLEATCEKLNR NSEL EILCLE
Sbjct: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLE 119
Query: 150 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 209
KELKEEKSKHSEQ+ELMADISKRIQSLEDESKSLKSQVAEAKMTFK FQ NEERL+I I+
Sbjct: 120 KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQ 179
Query: 210 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 269
DA ENS+LQESQKQLLQEAEVWKEQVSEL KQK TFEDSKVHAEQVLNDKE+HIKTLTE
Sbjct: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
Query: 270 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 329
RLLKMKD AML ED+TDDDNLELEMNSESE+GAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTL 299
Query: 330 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 389
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE+ENQKLQQKLKVMTELY
Sbjct: 300 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
Query: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
QENEMKL+RKL VEE RLEKEEKLSKVDE ISHATEELETYRKRAKDL +E E+TIH Y
Sbjct: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFY 418
Query: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
Q +II HEKKAHDNW AA AERNLNDLRKENAHNRQKLTE E K +LLEKDPY LDVPN
Sbjct: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPN 478
Query: 510 TAF-------------------------------------------GRGSRGPGNPLDHQ 526
TAF GRGSRGPGNP DHQ
Sbjct: 479 TAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQ 538
Query: 527 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 586
IT ERGESSCDRLTDPHRAPSD G L+PPW+QD RMMFPPPGQSYPDSALPPQRQDRF S
Sbjct: 539 ITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYS 598
Query: 587 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 646
N RLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKD+LGNL VPDSSLPAENEATGP
Sbjct: 599 NCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGP 658
Query: 647 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 706
GFVPPPLAPIRG LFPVD RGPF+RRGPPFPPPPPG +FGAS DYF P D PGPP APFA
Sbjct: 659 GFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFA 718
Query: 707 MRNVYPPRGFPPYLPPRPGFFPPPP 731
MRNVY PRGF PY PPRP FFPP P
Sbjct: 719 MRNVYLPRGFLPYRPPRPAFFPPAP 743
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 282 bits (722), Expect = 7e-76
Identities = 236/780 (30%), Positives = 381/780 (48%), Gaps = 83/780 (10%)
Query: 2 EEPG-VTPQPYLGLLLEEL-----RRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAV 55
EEP VTP LL+ + +VA LP+ ++P + YG PW+ V A +G +
Sbjct: 1134 EEPASVTPLENAILLIYSFMFYLTKSLVATLPDDVQPGPDFYGLPWKPVFITAFLGIASF 1193
Query: 56 LFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQ---KEYEGYEVESSL 112
FLWR+ V+ R+Y E++++ L +++E ++L++K S + KE + + E+
Sbjct: 1194 AIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQETRK 1253
Query: 113 KDASFEKEATEAQSLEATCEKLNRSNSE-LEDEILCLEKELKEEKSKHSEQDELMADISK 171
++ EA + + T EK N E L+D L L+ E+ ++ + +L+++ K
Sbjct: 1254 QNMILSDEAIKYKDKIKTLEK----NQEILDDTAKNLRVMLESEREQNVKNQDLISENKK 1309
Query: 172 RIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEV 231
I+ L+D S+ +E ++ +++EE++K EN++L++ ++QL QE E
Sbjct: 1310 SIEKLKDVISMNASEFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIED 1369
Query: 232 WKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE-----RLLKMKDWAAMLGEDIT 286
W + +EL++Q +FE S+ E L K+ +I LT LL+ + + +
Sbjct: 1370 WSKLHAELSEQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECESESEGQNKGGN 1429
Query: 287 DDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKT 346
D D L + E G + K +K+++ ++ ++ +E + + ++L T
Sbjct: 1430 DSDEL-----ANGEVGGDRNEKMKNQIKQMMDVSRTQTAISVVEEDLKLLQLKLRASVST 1484
Query: 347 KEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENY 406
K L + +K L+ ++ SLQ+ E+E + L+QK++++ ELYQ+ EM L +KL+ EE
Sbjct: 1485 KCNLEDQVKKLEDDRNSLQAAKAGLEDECKTLRQKVEILNELYQQKEMALQKKLSQEEYE 1544
Query: 407 RLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 466
R E+E +LS DEK A EE++TY++R +++E+EL++T S++ QI +HEKKAH+NWL
Sbjct: 1545 RQEREHRLSAADEKAVSAAEEVKTYKRRIEEMEDELQKTERSFKNQIATHEKKAHENWLK 1604
Query: 467 ARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPLDHQ 526
AR AER + + ++E A+ R KL E K +L+++P + PG P + Q
Sbjct: 1605 ARAAERAIAEEKREAANLRHKLLELTQKMAMLQEEPVIV----------KPMPGKP-NTQ 1653
Query: 527 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 586
RG S + P +P G SPP + PP + P SA R+D S
Sbjct: 1654 NPPRRGPLSQNGSFGP--SPVSGGECSPP------LTVEPPVR--PLSA-TLNRRDMPRS 1702
Query: 587 NSGRLSGP-------AELRSFNMPSLDKMDGSMPSEMESSRNDTKD---DLGNLNV---- 632
G + GP AE PS D G+ SSR + D G +N+
Sbjct: 1703 EFGSVDGPLPHPRWSAEASGKPSPS-DPGSGTATMMNSSSRGSSPTRVLDEGKVNMAPKG 1761
Query: 633 --PDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGP-PFPPP-PPGAMFGAS 688
P +P + G G VPPP+ GP P GPF GP P PPP PG
Sbjct: 1762 PPPFPGVPLMSTPMG-GPVPPPIR--YGP--PPQLCGPF---GPRPLPPPFGPGMRPPLG 1813
Query: 689 RDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLP-----PRPGFFPP---PPHSEGRSEFP 740
F PG PG P R P G P+ P PR F P PP + G E+P
Sbjct: 1814 LREFAPGVPPGRRDLPLHPRGFLP--GHAPFRPLGSLGPREYFIPGTRLPPPTHGPQEYP 1871
Score = 42.0 bits (97), Expect = 0.002
Identities = 87/430 (20%), Positives = 175/430 (40%), Gaps = 48/430 (11%)
Query: 80 LMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK-LNRSN 138
L++S +E+ L ++F QK + +E+E+ L++ S + ++ + +SL EK L++
Sbjct: 924 LIISSFFKEQQSL-QRF---QKYFNVHELEALLQEMSSKLKSAQQESLPYNMEKVLDKVF 979
Query: 139 SELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQ 198
E +IL + +++ + + + D+ ++ +E+ L
Sbjct: 980 RASESQILSIAEKMLDTRVAENR------DLGMNENNIFEEAAVLDDIQDLIYFVRYKHS 1033
Query: 199 MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ-VL 257
EE + + L E + Q L E +E+ +ELN V + H +Q V+
Sbjct: 1034 TAEETATLVMAPPLEEGLGGAMEEMQPLHEDNFSREKTAELN---VQVPEEPTHLDQRVI 1090
Query: 258 NDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE-LEMNSESENGAYLDNPPKGALKKL 316
D +H ++++ KD G T+D ++ ++ N + E
Sbjct: 1091 GD--THASEVSQKPNTEKDLDP--GPVTTEDTPMDAIDANKQPET--------------- 1131
Query: 317 IHAAKLNASLKTLEGERNQIYIQLSEVDKT-KEELTEHIK------NLQTEQASLQSENT 369
AA+ AS+ LE IY + + K+ L + ++ L + + +
Sbjct: 1132 --AAEEPASVTPLENAILLIYSFMFYLTKSLVATLPDDVQPGPDFYGLPWKPVFITAFLG 1189
Query: 370 HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELE 429
+ L V +YQ E ++ KL E +KLS ++KI + + ++
Sbjct: 1190 IASFAIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQ 1249
Query: 430 TYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLT 489
RK+ L +E + Y+ +I + EK A+N L R++N N+ ++
Sbjct: 1250 ETRKQNMILSDEAIK----YKDKIKTLEKNQEILDDTAKNLRVMLESEREQNVKNQDLIS 1305
Query: 490 ETELKFELLE 499
E + E L+
Sbjct: 1306 ENKKSIEKLK 1315
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 98.2 bits (243), Expect = 2e-20
Identities = 91/430 (21%), Positives = 189/430 (43%), Gaps = 43/430 (10%)
Query: 89 KSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCL 148
+SK + + ++++Y E + K ++E + ++ E +L E E +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 149 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 208
+ +++ ++H + D+ + + E+E +SL S++ + ++ + + +L +
Sbjct: 501 QSYIRKRTAEHEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 209 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ---VLNDKESHIK 265
+ +N+ LQ + +L++ E K Q+ + + Q + V AE+ V+ +K+ IK
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 266 TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS 325
+ L +D E++ D N+ + +E + L N A +L
Sbjct: 618 QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL--------- 668
Query: 326 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ------ 379
E + +Y++ ++ +E+L I N E L +N ++E QKLQ
Sbjct: 669 ----EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQ 724
Query: 380 ---QKLKVMTELYQENEMKLHRKLTVEENYRL------EKEEKLSKVDEKISHATEELET 430
++ M + QE + KL TVEE KEE+L+ + + S T+E++
Sbjct: 725 PNKDVVEQMEKCIQEKDEKLK---TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD 781
Query: 431 YRKRAKD------LEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 484
+ + D L EEL++ IH G+I S E+ L N E+ + DL++E
Sbjct: 782 LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 485 RQKLTETELK 494
++++ +L+
Sbjct: 842 KEEIGNVQLE 851
Score = 70.9 bits (172), Expect = 4e-12
Identities = 102/442 (23%), Positives = 192/442 (43%), Gaps = 41/442 (9%)
Query: 75 EKKLALMLSGLIEEKSKLLE---------KFSLVQKEYEGYEVESSLKDASFEKEATEAQ 125
EK L ++ ++E LL+ K L +KE + L+D E E+ +A
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 126 SLEATCEKLNRSNS-----ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
E L ++S ELE + E ELK ++ E++ ++ ++ +Q ++DE+
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 970
Query: 181 KSLKSQVAEAK----MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 236
K KSQ+ + K F +EE LK+ I + E S L L E +++
Sbjct: 971 KLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 237 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 296
++L ++ ++ E++L DK + KT ER ++ + + +++ ++ +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVN--KTSKERQQQV-EAVELEAKEVLKKLFPKVSVP 1086
Query: 297 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEELTE 352
S G +L K A K+ + + +K LE E ++++ L E +K K L E
Sbjct: 1087 SNLSYGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAE 1145
Query: 353 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLE 409
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E
Sbjct: 1146 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1205
Query: 410 KEEKLSKVDEKISHATEELETY---RKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 466
+E ++ ++ A E TY + KDL EL++ + + + ++ + L
Sbjct: 1206 REH----LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELN---LL 1258
Query: 467 ARNAERNLNDLRKENAHNRQKL 488
L LR E + RQK+
Sbjct: 1259 KAQLNETLTKLRTEQ-NERQKV 1279
Score = 38.9 bits (89), Expect = 0.018
Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 198 QMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVL 257
+ ++E ++ KD L + S+ + L ++ KE+ S V + +
Sbjct: 274 ETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEK-------------SGVIQDALK 320
Query: 258 NDKESHIKTLTERLLKMKDWAAMLGEDI--TDD--DNLELEMNSESENGAYLDNPPKGAL 313
+ + TL +L + A + ED T D L EM +E E
Sbjct: 321 KSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKE------------- 367
Query: 314 KKLIHAAKLNASLKTLEGE----RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN- 368
+ + ++ + TLE E +N+I++ E + + + + + ++ E A L+ EN
Sbjct: 368 RSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENG 427
Query: 369 ---THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT 425
N +L+ K +++ +L +LT E+ +L++EE K E+ A
Sbjct: 428 ILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELT-EKTGKLQQEEVQKKNAEQ---AA 483
Query: 426 EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNR 485
+L+ + A+ EE++ I + + ++ ++A N ++L+ + ++
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 486 QKLTE 490
Q+L +
Sbjct: 544 QQLEQ 548
Score = 30.4 bits (67), Expect = 6.4
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 12/157 (7%)
Query: 82 LSGLIEEKSKLLEKFSLVQKEYEGYEVE-SSLKDASFEKEATEAQSLEATCEKLNRSNSE 140
+ L E+ L + + E Y E LKD E + + L+ + + R N E
Sbjct: 1199 IENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ----KKLDDSYSEAVRQNEE 1254
Query: 141 LEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLE-DESKSLKSQ-----VAEAKMTF 194
L L + L + +++ +E+ ++ D+ K QSLE +SK +K+ + + ++
Sbjct: 1255 LNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSP 1314
Query: 195 KIFQMNEERLKIAIKDALNENSQ-LQESQKQLLQEAE 230
+ +E + +++ + + Q LQ +QL +E E
Sbjct: 1315 ETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 98.2 bits (243), Expect = 2e-20
Identities = 91/430 (21%), Positives = 189/430 (43%), Gaps = 43/430 (10%)
Query: 89 KSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCL 148
+SK + + ++++Y E + K ++E + ++ E +L E E +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 149 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 208
+ +++ ++H + D+ + + E+E +SL S++ + ++ + + +L +
Sbjct: 501 QSYIRKRTAEHEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 209 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ---VLNDKESHIK 265
+ +N+ LQ + +L++ E K Q+ + + Q + V AE+ V+ +K+ IK
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 266 TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS 325
+ L +D E++ D N+ + +E + L N A +L
Sbjct: 618 QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL--------- 668
Query: 326 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ------ 379
E + +Y++ ++ +E+L I N E L +N ++E QKLQ
Sbjct: 669 ----EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQ 724
Query: 380 ---QKLKVMTELYQENEMKLHRKLTVEENYRL------EKEEKLSKVDEKISHATEELET 430
++ M + QE + KL TVEE KEE+L+ + + S T+E++
Sbjct: 725 PNKDVVEQMEKCIQEKDEKLK---TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD 781
Query: 431 YRKRAKD------LEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 484
+ + D L EEL++ IH G+I S E+ L N E+ + DL++E
Sbjct: 782 LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 485 RQKLTETELK 494
++++ +L+
Sbjct: 842 KEEIGNVQLE 851
Score = 66.6 bits (161), Expect = 8e-11
Identities = 94/422 (22%), Positives = 179/422 (42%), Gaps = 63/422 (14%)
Query: 75 EKKLALMLSGLIEEKSKLLE---------KFSLVQKEYEGYEVESSLKDASFEKEATEAQ 125
EK L ++ ++E LL+ K L +KE + L+D E E+ +A
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 126 SLEATCEKLNRSNS-----ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
E L ++S ELE + E ELK ++ E++ ++ ++ +Q ++DE+
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 970
Query: 181 KSLKSQVAEAK----MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 236
K KSQ+ + K F +EE LK+ + E +K++ + +W E
Sbjct: 971 KLFKSQIEQLKQQNYQQASSFPPHEELLKV-----------ISEREKEI---SGLWNELD 1016
Query: 237 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 296
S +D+ H + N+++ ++ + L+ K+ L ++ NL
Sbjct: 1017 S--------LKDAVEHQRKKNNERQQQVEAVE---LEAKEVLKKLFPKVSVPSNLSY--- 1062
Query: 297 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEELTE 352
G +L K A K+ + + +K LE E ++++ L E +K K L E
Sbjct: 1063 -----GEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAE 1116
Query: 353 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLE 409
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E
Sbjct: 1117 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1176
Query: 410 KEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARN 469
+E ++ ++ A E TY ++L+ +L T+ + + +K A D A ++
Sbjct: 1177 REH----LEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQS 1232
Query: 470 AE 471
E
Sbjct: 1233 LE 1234
Score = 38.9 bits (89), Expect = 0.018
Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 198 QMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVL 257
+ ++E ++ KD L + S+ + L ++ KE+ S V + +
Sbjct: 274 ETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEK-------------SGVIQDALK 320
Query: 258 NDKESHIKTLTERLLKMKDWAAMLGEDI--TDD--DNLELEMNSESENGAYLDNPPKGAL 313
+ + TL +L + A + ED T D L EM +E E
Sbjct: 321 KSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKE------------- 367
Query: 314 KKLIHAAKLNASLKTLEGE----RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN- 368
+ + ++ + TLE E +N+I++ E + + + + + ++ E A L+ EN
Sbjct: 368 RSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENG 427
Query: 369 ---THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT 425
N +L+ K +++ +L +LT E+ +L++EE K E+ A
Sbjct: 428 ILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELT-EKTGKLQQEEVQKKNAEQ---AA 483
Query: 426 EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNR 485
+L+ + A+ EE++ I + + ++ ++A N ++L+ + ++
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 486 QKLTE 490
Q+L +
Sbjct: 544 QQLEQ 548
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 98.2 bits (243), Expect = 2e-20
Identities = 91/430 (21%), Positives = 189/430 (43%), Gaps = 43/430 (10%)
Query: 89 KSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCL 148
+SK + + ++++Y E + K ++E + ++ E +L E E +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 149 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 208
+ +++ ++H + D+ + + E+E +SL S++ + ++ + + +L +
Sbjct: 501 QSYIRKRTAEHEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 209 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQ---VLNDKESHIK 265
+ +N+ LQ + +L++ E K Q+ + + Q + V AE+ V+ +K+ IK
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 266 TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS 325
+ L +D E++ D N+ + +E + L N A +L
Sbjct: 618 QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL--------- 668
Query: 326 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ------ 379
E + +Y++ ++ +E+L I N E L +N ++E QKLQ
Sbjct: 669 ----EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQ 724
Query: 380 ---QKLKVMTELYQENEMKLHRKLTVEENYRL------EKEEKLSKVDEKISHATEELET 430
++ M + QE + KL TVEE KEE+L+ + + S T+E++
Sbjct: 725 PNKDVVEQMEKCIQEKDEKLK---TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD 781
Query: 431 YRKRAKD------LEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 484
+ + D L EEL++ IH G+I S E+ L N E+ + DL++E
Sbjct: 782 LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 485 RQKLTETELK 494
++++ +L+
Sbjct: 842 KEEIGNVQLE 851
Score = 70.9 bits (172), Expect = 4e-12
Identities = 102/442 (23%), Positives = 192/442 (43%), Gaps = 41/442 (9%)
Query: 75 EKKLALMLSGLIEEKSKLLE---------KFSLVQKEYEGYEVESSLKDASFEKEATEAQ 125
EK L ++ ++E LL+ K L +KE + L+D E E+ +A
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 126 SLEATCEKLNRSNS-----ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDES 180
E L ++S ELE + E ELK ++ E++ ++ ++ +Q ++DE+
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 970
Query: 181 KSLKSQVAEAK----MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 236
K KSQ+ + K F +EE LK+ I + E S L L E +++
Sbjct: 971 KLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 237 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 296
++L ++ ++ E++L DK + KT ER ++ + + +++ ++ +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVN--KTSKERQQQV-EAVELEAKEVLKKLFPKVSVP 1086
Query: 297 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEELTE 352
S G +L K A K+ + + +K LE E ++++ L E +K K L E
Sbjct: 1087 SNLSYGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAE 1145
Query: 353 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLE 409
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E
Sbjct: 1146 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1205
Query: 410 KEEKLSKVDEKISHATEELETY---RKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 466
+E ++ ++ A E TY + KDL EL++ + + + ++ + L
Sbjct: 1206 REH----LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELN---LL 1258
Query: 467 ARNAERNLNDLRKENAHNRQKL 488
L LR E + RQK+
Sbjct: 1259 KAQLNETLTKLRTEQ-NERQKV 1279
Score = 38.9 bits (89), Expect = 0.018
Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 198 QMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVL 257
+ ++E ++ KD L + S+ + L ++ KE+ S V + +
Sbjct: 274 ETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEK-------------SGVIQDALK 320
Query: 258 NDKESHIKTLTERLLKMKDWAAMLGEDI--TDD--DNLELEMNSESENGAYLDNPPKGAL 313
+ + TL +L + A + ED T D L EM +E E
Sbjct: 321 KSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKE------------- 367
Query: 314 KKLIHAAKLNASLKTLEGE----RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN- 368
+ + ++ + TLE E +N+I++ E + + + + + ++ E A L+ EN
Sbjct: 368 RSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENG 427
Query: 369 ---THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT 425
N +L+ K +++ +L +LT E+ +L++EE K E+ A
Sbjct: 428 ILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELT-EKTGKLQQEEVQKKNAEQ---AA 483
Query: 426 EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNR 485
+L+ + A+ EE++ I + + ++ ++A N ++L+ + ++
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 486 QKLTE 490
Q+L +
Sbjct: 544 QQLEQ 548
Score = 30.4 bits (67), Expect = 6.4
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 12/157 (7%)
Query: 82 LSGLIEEKSKLLEKFSLVQKEYEGYEVE-SSLKDASFEKEATEAQSLEATCEKLNRSNSE 140
+ L E+ L + + E Y E LKD E + + L+ + + R N E
Sbjct: 1199 IENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ----KKLDDSYSEAVRQNEE 1254
Query: 141 LEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLE-DESKSLKSQ-----VAEAKMTF 194
L L + L + +++ +E+ ++ D+ K QSLE +SK +K+ + + ++
Sbjct: 1255 LNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSP 1314
Query: 195 KIFQMNEERLKIAIKDALNENSQ-LQESQKQLLQEAE 230
+ +E + +++ + + Q LQ +QL +E E
Sbjct: 1315 ETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 85.1 bits (209), Expect = 2e-16
Identities = 108/453 (23%), Positives = 198/453 (43%), Gaps = 43/453 (9%)
Query: 79 ALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSN 138
+L L +E+ S+ E QK G+EV + L + K E QSL T E+L +
Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSL-GHEV-NELTSSRLLKLEMENQSLTKTVEELRTTV 483
Query: 139 SELE---DEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 195
+E +IL +EKE + K + + + +Q+ ++ SK L + A+ + T +
Sbjct: 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 196 IFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE-QVSELNKQ------------ 242
+ N ER IK EN L ++ L Q +++ E +V ++ K+
Sbjct: 544 TLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS 600
Query: 243 ----KVTFEDSKVHAE-QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNS 297
K+ FE ++ E + +K + L L ++ +L + IT+ ++ +
Sbjct: 601 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Query: 298 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 357
+ + L+ + K L L L++LE E + QL E + E +K
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS----QLDEENLELRRNVESLKCA 716
Query: 358 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENE-MKLHRKLTVEENYRLEKEEKLSK 416
+ A LQ EN E+E ++L++ L+++ +++ E +++ + EN RL+K L
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK--TLEN 774
Query: 417 VDEKISHATEELETYRKRAKDLEEELER-TIHSYQGQIISHEKKAHDNWLAARNAERNLN 475
++KI EL+ + L++ LE I S + + + E K+ + E++
Sbjct: 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKDKK 832
Query: 476 DLRKENAHNRQK-------LTETELKFELLEKD 501
L KEN RQ+ L E +K LEK+
Sbjct: 833 QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Score = 82.4 bits (202), Expect = 1e-15
Identities = 117/495 (23%), Positives = 203/495 (41%), Gaps = 84/495 (16%)
Query: 74 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE-----KEATEAQSLE 128
+ ++L + GL E +L + K+ + ++ES L+D E K E +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 129 ATCEKLNRSNSELEDEILCLEKELK--EEKSKHSEQ-----DELMADISKRIQSLEDESK 181
E+L + N LE E LEK+ K E+++K Q D + + + +I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 182 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 241
+L ++ K + + E+ K +K A + L ++ L+ E ++ ++L K
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Query: 242 QKVTFEDSKVHAEQVLND--------------------------KESHIKTLTERLLKMK 275
E ++ E++L+D KE I L RL +
Sbjct: 928 LTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEEST 987
Query: 276 DWAAMLGEDI-TDDDNLELEMNSESENGAYLDNPP----------------KGALK---K 315
++ L +++ T N E + E +PP + LK +
Sbjct: 988 NYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR 1047
Query: 316 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENEN 375
LI + NA TL+ E+ + QL +++ L I LQ + SLQ +NT + +N
Sbjct: 1048 LIEVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1104
Query: 376 QKLQQKLKVM----TELYQENEMKLHRKLTVE-ENYRLEKE-EKLSKVDEKISHATEELE 429
KLQ + + T L +N L ++ ++E EN + KE E L + + + E+LE
Sbjct: 1105 AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLE 1164
Query: 430 TYRKRAKDLEEELERTIHSYQGQIISHE--KKAHDNW-LAARNAERNLNDLRKENA--HN 484
ER Y+ I H K AH N + R+ E N L K+ +
Sbjct: 1165 LLH----------ERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1214
Query: 485 RQKLTETELKFELLE 499
+K+ + E + LLE
Sbjct: 1215 LEKMLKVEQEKMLLE 1229
Score = 78.6 bits (192), Expect = 2e-14
Identities = 115/476 (24%), Positives = 200/476 (42%), Gaps = 75/476 (15%)
Query: 65 SVRSRLYVGREKKLA------LMLSGLIEEKSKLLEKFSL----VQKEYEGY-------- 106
S+R R + E ++ +L I+E S L K ++KE E Y
Sbjct: 569 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 107 EVESSLKDASFEKEATEAQ--SLEATCEK---LNRSNSELEDEILCLEKELKEEKSKHSE 161
E+E+ L E E + + +L+ TCEK L + NSELE E L+K L K+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN---- 684
Query: 162 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALN---ENSQL 218
++ +++SLE E+ L + E + N E LK A EN +L
Sbjct: 685 -------LTFQLESLEKENSQLDEENLELRR-------NVESLKCASMKMAQLQLENKEL 730
Query: 219 QESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWA 278
+ ++QL + E+ K + + +V+++ + +++ E+ K + + +++D
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 279 AMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 338
E+ T NLE E+ S+ L+ K ++ ++L K LE E ++
Sbjct: 791 M---ENQTLQKNLE-ELKISSKRLEQLEKENKSLEQE---TSQLEKDKKQLEKENKRLRQ 843
Query: 339 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 398
Q D T EE I NL+ E +L E ++ +L++ K EL + + +
Sbjct: 844 QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 399 KLTVEENYRLE--KEEKLSKVDEKISHATE------------ELETYRKRAKDLEEELER 444
+T+ E+ E K ++++ EK++H E E T R K LE +LE
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLES 963
Query: 445 TIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 500
T+ + I EK A E L + N RQ+L + +E L++
Sbjct: 964 TLK--KSLEIKEEKIA--------ALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Score = 68.9 bits (167), Expect = 2e-11
Identities = 92/452 (20%), Positives = 200/452 (44%), Gaps = 48/452 (10%)
Query: 85 LIEEKSKLLE-KFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEAT-CEKLNRSNSELE 142
L++ K +L + + L + + E + S + A ++ +A +A +KL S +
Sbjct: 274 LLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYK 333
Query: 143 DEILCLE------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKI 196
+ + +E +ELKE+ E ++ D + ++ D+ L+ + + K
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHD 393
Query: 197 FQMNEERLKIAIKDALNENSQLQESQKQLLQEA--EVWK-------EQVSELNKQKVTFE 247
+M + + I++ + EN L+ +QKQ + E+ W+ ++SE ++ + E
Sbjct: 394 MEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Query: 248 DSKVHAEQVLN---DKESHIKTLTE-------------RLLKMKDWAAMLGEDITDDDNL 291
+++ + ++L + +S KT+ E ++LKM+ L + + + L
Sbjct: 454 VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKV---EIL 510
Query: 292 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL-EGERNQIYIQLSEVDKTKEEL 350
E E+ E ++ N K +K+ A+L +++TL E QI I +++ E L
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLRENSERQIKI----LEQENEHL 563
Query: 351 TEHIKNL-QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 409
+ + +L Q Q S ++ E EN+ L + +K + + E + R++ E + E
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFE-KRQIKKELEHYKE 622
Query: 410 KEEKLSKVDEKISHATEELETYRKRAKDLEEELER--TIHSYQGQIISHEKKAHDNWLAA 467
K E+ +++ ++ H +E E +K+ +L+ E+ + ++ +K +
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF 682
Query: 468 RNAERNLNDLRKENAHNRQKLTETELKFELLE 499
+N L L KEN+ ++ E E L+
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Score = 60.1 bits (144), Expect = 8e-09
Identities = 95/452 (21%), Positives = 201/452 (44%), Gaps = 79/452 (17%)
Query: 74 REKKLALMLSGLIEEKS---KLLEKFSLVQKEYEGYE--------VESSLKDASFEKEAT 122
+E+K+A + + L E + +L ++ V+K YE + V+SS S E
Sbjct: 972 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS-PPISGEDNKW 1030
Query: 123 EAQSLEATCEKLN---------RSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 173
E +S E T E L R+N+ L+ E L+ +LK+ +++++ + + ++
Sbjct: 1031 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1090
Query: 174 QSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 233
SL++++ +L++Q A+ Q+ L +N+N+QL L+Q++ +
Sbjct: 1091 VSLQEQNTTLQTQNAK-------LQVENSTLNSQSTSLMNQNAQL------LIQQSSLEN 1137
Query: 234 EQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDIT---DDDN 290
E S + ++ ED K + ++ D E ++ L ER + ++ +++ + T N
Sbjct: 1138 ENESVIKER----EDLKSLYDSLIKDHEK-LELLHER--QASEYESLISKHGTLKSAHKN 1190
Query: 291 LELEMNSESENGAYLDNPPKGALKKLIHAAKL--------NASLKTLEGERNQIYIQLSE 342
LE+E + L KG L+ L K+ N + +T+ E ++ +
Sbjct: 1191 LEVEHRDLEDRYNQLLKQ-KGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1249
Query: 343 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 402
++ T +L + + LQT+ +L+S + + E +L+ + + E YQ+ ++ +
Sbjct: 1250 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDI-----TST 1304
Query: 403 EENYRLEKEEKL-SKVDEKISHATEELETYRKRAKDLEE---ELERTIHSYQGQIISHEK 458
+ N + E +L ++E+ H ++++T + + L E E + H Q Q I
Sbjct: 1305 KLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYID--- 1361
Query: 459 KAHDNWLAARNAERNLNDLRKENAHNRQKLTE 490
LN+LR++ +K+ +
Sbjct: 1362 --------------KLNELRRQKEKLEEKIMD 1379
Score = 41.2 bits (95), Expect = 0.004
Identities = 44/212 (20%), Positives = 86/212 (40%), Gaps = 11/212 (5%)
Query: 72 VGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATC 131
+ + L + LI++ KL EYE + ++ + E + LE
Sbjct: 1143 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1202
Query: 132 EKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 191
+L + +LED LEK LK E+ K +++ ++ + L E+ L ++
Sbjct: 1203 NQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1258
Query: 192 MTFKIFQMNEERLKIAIKDALNEN-------SQLQESQKQLLQEAEVWKEQVSELNKQKV 244
++ Q + + LK + ++ E S+L+E +QL + Q L++ K
Sbjct: 1259 KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKG 1318
Query: 245 TFEDSKVHAEQVLNDKESHIKTLTERLLKMKD 276
E+ H + +TL E+ ++ KD
Sbjct: 1319 NLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1350
Score = 35.0 bits (79), Expect = 0.26
Identities = 44/198 (22%), Positives = 88/198 (44%), Gaps = 23/198 (11%)
Query: 73 GREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCE 132
G +L S L++E L ++ ++E + +A F K + Q L+ T
Sbjct: 1245 GENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITST 1304
Query: 133 KLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM 192
KLN + E+L K EE+++H + +IQ+L ++++L Q E+K
Sbjct: 1305 KLNN-----QCELLSQLKGNLEEENRH---------LLDQIQTLMLQNRTLLEQNMESKD 1350
Query: 193 TFKIFQMNEERLKIAIKDALNE-NSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK- 250
F + E+R I D LNE Q ++ +++++ + + + +T + K
Sbjct: 1351 LFHV----EQRQYI---DKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKL 1403
Query: 251 VHAEQVLNDKESHIKTLT 268
+ +++ +N + TLT
Sbjct: 1404 IKSKKDINRERQKSLTLT 1421
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 85.1 bits (209), Expect = 2e-16
Identities = 108/453 (23%), Positives = 198/453 (43%), Gaps = 43/453 (9%)
Query: 79 ALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSN 138
+L L +E+ S+ E QK G+EV + L + K E QSL T E+L +
Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSL-GHEV-NELTSSRLLKLEMENQSLTKTVEELRTTV 483
Query: 139 SELE---DEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 195
+E +IL +EKE + K + + + +Q+ ++ SK L + A+ + T +
Sbjct: 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 196 IFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE-QVSELNKQ------------ 242
+ N ER IK EN L ++ L Q +++ E +V ++ K+
Sbjct: 544 TLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS 600
Query: 243 ----KVTFEDSKVHAE-QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNS 297
K+ FE ++ E + +K + L L ++ +L + IT+ ++ +
Sbjct: 601 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Query: 298 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 357
+ + L+ + K L L L++LE E + QL E + E +K
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS----QLDEENLELRRNVESLKCA 716
Query: 358 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENE-MKLHRKLTVEENYRLEKEEKLSK 416
+ A LQ EN E+E ++L++ L+++ +++ E +++ + EN RL+K L
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK--TLEN 774
Query: 417 VDEKISHATEELETYRKRAKDLEEELER-TIHSYQGQIISHEKKAHDNWLAARNAERNLN 475
++KI EL+ + L++ LE I S + + + E K+ + E++
Sbjct: 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKDKK 832
Query: 476 DLRKENAHNRQK-------LTETELKFELLEKD 501
L KEN RQ+ L E +K LEK+
Sbjct: 833 QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Score = 82.8 bits (203), Expect = 1e-15
Identities = 117/494 (23%), Positives = 203/494 (41%), Gaps = 83/494 (16%)
Query: 74 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE-----KEATEAQSLE 128
+ ++L + GL E +L + K+ + ++ES L+D E K E +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 129 ATCEKLNRSNSELEDEILCLEKELK--EEKSKHSEQ-----DELMADISKRIQSLEDESK 181
E+L + N LE E LEK+ K E+++K Q D + + + +I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 182 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 241
+L ++ K + + E+ K +K A + L ++ L+ E ++ ++L K
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Query: 242 QKVTFEDSKVHAEQVLND-------------------------KESHIKTLTERLLKMKD 276
E ++ E++L+D KE I L RL + +
Sbjct: 928 LTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN 987
Query: 277 WAAMLGEDI-TDDDNLELEMNSESENGAYLDNPP----------------KGALK---KL 316
+ L +++ T N E + E +PP + LK +L
Sbjct: 988 YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRL 1047
Query: 317 IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQ 376
I + NA TL+ E+ + QL +++ L I LQ + SLQ +NT + +N
Sbjct: 1048 IEVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1104
Query: 377 KLQQKLKVM----TELYQENEMKLHRKLTVE-ENYRLEKE-EKLSKVDEKISHATEELET 430
KLQ + + T L +N L ++ ++E EN + KE E L + + + E+LE
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Query: 431 YRKRAKDLEEELERTIHSYQGQIISHE--KKAHDNW-LAARNAERNLNDLRKENA--HNR 485
ER Y+ I H K AH N + R+ E N L K+ +
Sbjct: 1165 LH----------ERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDL 1214
Query: 486 QKLTETELKFELLE 499
+K+ + E + LLE
Sbjct: 1215 EKMLKVEQEKMLLE 1228
Score = 80.9 bits (198), Expect = 4e-15
Identities = 109/467 (23%), Positives = 203/467 (43%), Gaps = 58/467 (12%)
Query: 65 SVRSRLYVGREKKLA------LMLSGLIEEKSKLLEKFSL----VQKEYEGY-------- 106
S+R R + E ++ +L I+E S L K ++KE E Y
Sbjct: 569 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 107 EVESSLKDASFEKEATEAQ--SLEATCEK---LNRSNSELEDEILCLEKELKEEKSKHSE 161
E+E+ L E E + + +L+ TCEK L + NSELE E L+K L K+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN---- 684
Query: 162 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALN---ENSQL 218
++ +++SLE E+ L + E + N E LK A EN +L
Sbjct: 685 -------LTFQLESLEKENSQLDEENLELRR-------NVESLKCASMKMAQLQLENKEL 730
Query: 219 QESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWA 278
+ ++QL + E+ K + + +V+++ + +++ E+ K + + +++D
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 279 AMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 338
E+ T NLE E+ S+ L+ K ++ ++L K LE E ++
Sbjct: 791 M---ENQTLQKNLE-ELKISSKRLEQLEKENKSLEQE---TSQLEKDKKQLEKENKRLRQ 843
Query: 339 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 398
Q D T EE I NL+ E +L E ++ +L++ K EL + + +
Sbjct: 844 QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 399 KLTVEENYRLE--KEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISH 456
+T+ E+ E K ++++ EK++H E++ ++R E+ + + ++ S
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEST 963
Query: 457 EKKA---HDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 500
KK+ + +AA E L + N RQ+L + +E L++
Sbjct: 964 LKKSLEIKEEKIAA--LEARLEESTNYNQQLRQELKTVKKNYEALKQ 1008
Score = 68.9 bits (167), Expect = 2e-11
Identities = 92/452 (20%), Positives = 200/452 (44%), Gaps = 48/452 (10%)
Query: 85 LIEEKSKLLE-KFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEAT-CEKLNRSNSELE 142
L++ K +L + + L + + E + S + A ++ +A +A +KL S +
Sbjct: 274 LLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYK 333
Query: 143 DEILCLE------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKI 196
+ + +E +ELKE+ E ++ D + ++ D+ L+ + + K
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHD 393
Query: 197 FQMNEERLKIAIKDALNENSQLQESQKQLLQEA--EVWK-------EQVSELNKQKVTFE 247
+M + + I++ + EN L+ +QKQ + E+ W+ ++SE ++ + E
Sbjct: 394 MEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Query: 248 DSKVHAEQVLN---DKESHIKTLTE-------------RLLKMKDWAAMLGEDITDDDNL 291
+++ + ++L + +S KT+ E ++LKM+ L + + + L
Sbjct: 454 VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKV---EIL 510
Query: 292 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL-EGERNQIYIQLSEVDKTKEEL 350
E E+ E ++ N K +K+ A+L +++TL E QI I +++ E L
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLRENSERQIKI----LEQENEHL 563
Query: 351 TEHIKNL-QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 409
+ + +L Q Q S ++ E EN+ L + +K + + E + R++ E + E
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFE-KRQIKKELEHYKE 622
Query: 410 KEEKLSKVDEKISHATEELETYRKRAKDLEEELER--TIHSYQGQIISHEKKAHDNWLAA 467
K E+ +++ ++ H +E E +K+ +L+ E+ + ++ +K +
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF 682
Query: 468 RNAERNLNDLRKENAHNRQKLTETELKFELLE 499
+N L L KEN+ ++ E E L+
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Score = 60.1 bits (144), Expect = 8e-09
Identities = 95/452 (21%), Positives = 201/452 (44%), Gaps = 79/452 (17%)
Query: 74 REKKLALMLSGLIEEKS---KLLEKFSLVQKEYEGYE--------VESSLKDASFEKEAT 122
+E+K+A + + L E + +L ++ V+K YE + V+SS S E
Sbjct: 971 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS-PPISGEDNKW 1029
Query: 123 EAQSLEATCEKLN---------RSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 173
E +S E T E L R+N+ L+ E L+ +LK+ +++++ + + ++
Sbjct: 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Query: 174 QSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 233
SL++++ +L++Q A+ Q+ L +N+N+QL L+Q++ +
Sbjct: 1090 VSLQEQNTTLQTQNAK-------LQVENSTLNSQSTSLMNQNAQL------LIQQSSLEN 1136
Query: 234 EQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDIT---DDDN 290
E S + ++ ED K + ++ D E ++ L ER + ++ +++ + T N
Sbjct: 1137 ENESVIKER----EDLKSLYDSLIKDHEK-LELLHER--QASEYESLISKHGTLKSAHKN 1189
Query: 291 LELEMNSESENGAYLDNPPKGALKKLIHAAKL--------NASLKTLEGERNQIYIQLSE 342
LE+E + L KG L+ L K+ N + +T+ E ++ +
Sbjct: 1190 LEVEHRDLEDRYNQLLKQ-KGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1248
Query: 343 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 402
++ T +L + + LQT+ +L+S + + E +L+ + + E YQ+ ++ +
Sbjct: 1249 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDI-----TST 1303
Query: 403 EENYRLEKEEKL-SKVDEKISHATEELETYRKRAKDLEE---ELERTIHSYQGQIISHEK 458
+ N + E +L ++E+ H ++++T + + L E E + H Q Q I
Sbjct: 1304 KLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYID--- 1360
Query: 459 KAHDNWLAARNAERNLNDLRKENAHNRQKLTE 490
LN+LR++ +K+ +
Sbjct: 1361 --------------KLNELRRQKEKLEEKIMD 1378
Score = 41.2 bits (95), Expect = 0.004
Identities = 44/212 (20%), Positives = 86/212 (40%), Gaps = 11/212 (5%)
Query: 72 VGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATC 131
+ + L + LI++ KL EYE + ++ + E + LE
Sbjct: 1142 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1201
Query: 132 EKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 191
+L + +LED LEK LK E+ K +++ ++ + L E+ L ++
Sbjct: 1202 NQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1257
Query: 192 MTFKIFQMNEERLKIAIKDALNEN-------SQLQESQKQLLQEAEVWKEQVSELNKQKV 244
++ Q + + LK + ++ E S+L+E +QL + Q L++ K
Sbjct: 1258 KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKG 1317
Query: 245 TFEDSKVHAEQVLNDKESHIKTLTERLLKMKD 276
E+ H + +TL E+ ++ KD
Sbjct: 1318 NLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1349
Score = 35.0 bits (79), Expect = 0.26
Identities = 44/198 (22%), Positives = 88/198 (44%), Gaps = 23/198 (11%)
Query: 73 GREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCE 132
G +L S L++E L ++ ++E + +A F K + Q L+ T
Sbjct: 1244 GENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITST 1303
Query: 133 KLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM 192
KLN + E+L K EE+++H + +IQ+L ++++L Q E+K
Sbjct: 1304 KLNN-----QCELLSQLKGNLEEENRH---------LLDQIQTLMLQNRTLLEQNMESKD 1349
Query: 193 TFKIFQMNEERLKIAIKDALNE-NSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK- 250
F + E+R I D LNE Q ++ +++++ + + + +T + K
Sbjct: 1350 LFHV----EQRQYI---DKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKL 1402
Query: 251 VHAEQVLNDKESHIKTLT 268
+ +++ +N + TLT
Sbjct: 1403 IKSKKDINRERQKSLTLT 1420
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 85.1 bits (209), Expect = 2e-16
Identities = 118/548 (21%), Positives = 239/548 (43%), Gaps = 58/548 (10%)
Query: 54 AVLFFLW--RSFRSVRSRLYVGREKKLALMLSGLIEEK--SKLLEKFSLVQKEYEGYEV- 108
A+L W R+F V++ ++ K+ +L EK + + E+F +++ E E
Sbjct: 812 ALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEAR 871
Query: 109 --ESSLKDASFEKEATEAQ-SLEATCEKLNRSNSELEDEI---LCLEKELKEEKSKHSEQ 162
E K S +E + Q ++A + LN + + I + LE ++KE + ++
Sbjct: 872 RKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDE 931
Query: 163 DELMADISKRIQSLEDESKSLKSQVAEAKMTF------------KIFQMNEER--LKIAI 208
+E+ A+++ + + LEDE LK + + ++T K+ + EE L I
Sbjct: 932 EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 991
Query: 209 KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLT 268
E LQE+ +Q L + +V +++V+ L+K KV E E L ++ L
Sbjct: 992 AKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLE 1051
Query: 269 ERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK-KLIHAAKLNASLK 327
K++ + E I D +N +L++ + + + N ++ + + A +L LK
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLK 1111
Query: 328 TLEGERNQIYIQL-------SEVDKTKEELTEHIKNL--QTEQA----SLQSE-NTHFEN 373
+ ++ +L ++V+K + +L+ ++ + + E+A S+Q E N E
Sbjct: 1112 ENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1171
Query: 374 ENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRK 433
E QK+++ L+ T ++ L +K E+ + L +V +K+ +E ++
Sbjct: 1172 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE---KEKSEFKL 1228
Query: 434 RAKDLEEELERTIHSYQG-QIISH--EKKAHDNWLAARNAERNLND-------LRKENAH 483
D+ +E+ I + + +S E +A++ + A+R+LND L+ EN
Sbjct: 1229 ELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGE 1288
Query: 484 NRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPG---NPLDHQITNERGESSCDRLT 540
++L E E L + + R G N L H + + R + CD L
Sbjct: 1289 LARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHD--CDLLR 1346
Query: 541 DPHRAPSD 548
+ + ++
Sbjct: 1347 EQYEEETE 1354
Score = 77.0 bits (188), Expect = 6e-14
Identities = 99/447 (22%), Positives = 195/447 (43%), Gaps = 61/447 (13%)
Query: 76 KKLALMLSGLIE---EKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEAT 130
K L +S L E E K + + V+K E E E++S+L++A E E + L A
Sbjct: 1505 KNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ 1564
Query: 131 CEKLNRSNSELEDEILCLEKELKEEKSKH-----SEQDELMADISKR------------- 172
E N+ +E+E ++ ++E+++ K H S Q L A+ R
Sbjct: 1565 LE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623
Query: 173 IQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVW 232
+ +E + AEA+ K Q + +I + DA+ N L+E+ + + +
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
Query: 233 KEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE 292
+ ++ EL E S+ AEQ L + ++ L + + + + D+T
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLT------ 1737
Query: 293 LEMNSESENGAY-LDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELT 351
++ SE E N + A K + AA + LK + + +++ K+ +
Sbjct: 1738 -QLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNME 1789
Query: 352 EHIKNLQ-----TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENY 406
+ IK+LQ EQ +L+ + + QKL+ +++ + E E++ +K E
Sbjct: 1790 QTIKDLQHRLDEAEQIALKGG----KKQLQKLEARVREL-----EGELEAEQKRNAESVK 1840
Query: 407 RLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLA 466
+ K E+ K ++++ TEE + R +DL ++L+ + +Y+ Q E++A+ N
Sbjct: 1841 GMRKSERRIK---ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSK 1897
Query: 467 ARNAERNLNDLRKENAHNRQKLTETEL 493
R + L++ A R + E+++
Sbjct: 1898 FRKVQHELDE-----AEERADIAESQV 1919
Score = 67.4 bits (163), Expect = 5e-11
Identities = 87/411 (21%), Positives = 172/411 (41%), Gaps = 44/411 (10%)
Query: 109 ESSLKDASFEKEATEA-QSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 167
E+ K A ++A EA +++ A C L ++ L++EI L +++ + + D+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 168 DISKRI----QSLEDESKSLKSQVAEAKM----TFKIFQMNEERLKIAIKDALNENSQLQ 219
+ K + Q E+ L+S EA+ FK+ EE L+ ++ EN LQ
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE-HLETFKRENKNLQ 1508
Query: 220 ESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAA 279
E L ++ + V EL K + E K+ + L + E+ ++ ++L+ +
Sbjct: 1509 EEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568
Query: 280 MLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNAS-----LKTLEGERN 334
+ +I + E + E E +L+ + A + + K +EG+ N
Sbjct: 1569 QIKAEI---ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 335 QIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEM 394
++ IQLS ++ E + +K+LQ+ Q + N L++ + +
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI---------- 1675
Query: 395 KLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRA-KDLEEELERT--IHSYQG 451
VE L + E E++ E+ E RK A ++L E ER +HS
Sbjct: 1676 -------VERRNNLLQAEL-----EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1723
Query: 452 QIISHEKKAHDNWLAARN-AERNLNDLRKENAHNRQKLTETELKFELLEKD 501
+I+ +KK + ++ E + + R ++ +T+ + E L+K+
Sbjct: 1724 SLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE 1774
Score = 61.6 bits (148), Expect = 3e-09
Identities = 92/422 (21%), Positives = 170/422 (40%), Gaps = 34/422 (8%)
Query: 107 EVESSLKDASFE--KEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDE 164
E + SL D + + K TE L E+ S+L L +++++ K + E+ +
Sbjct: 1267 EAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGK 1326
Query: 165 LMADISKRIQSLEDESKSLKSQV-----AEAKMTFKIFQMNEERLKIAIK---DALNENS 216
++ +QS + L+ Q A+A++ + + N E + K DA+
Sbjct: 1327 AKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE 1386
Query: 217 QLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK----VHAEQVLNDKESHIKTLTERLL 272
+L+E++K+L Q + +E V +N + + E +K E ++ D E
Sbjct: 1387 ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 1446
Query: 273 KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDN---PPKGALKK-LIHAAKLNASLKT 328
K +++ +L E + + E+ S + L K A ++ L H K
Sbjct: 1447 KQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1506
Query: 329 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTE----QASLQSENTHFENENQKLQQKLKV 384
L+ E + + QL E K EL + K L+ E Q++L+ E+E K+ +
Sbjct: 1507 LQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLE 1566
Query: 385 MTELYQENEMKLHRK----LTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 440
++ E E KL K + N++ + + +D + E L +K DL E
Sbjct: 1567 FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNE 1626
Query: 441 ------ELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENA--HNRQKLTETE 492
R Q Q+ S + D + +A R +DL++ A R L + E
Sbjct: 1627 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
Query: 493 LK 494
L+
Sbjct: 1687 LE 1688
Score = 60.1 bits (144), Expect = 8e-09
Identities = 92/437 (21%), Positives = 182/437 (41%), Gaps = 75/437 (17%)
Query: 94 EKFSLVQKEYEGYEVES-SLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKEL 152
+K+ Q E E + E+ SL F+ + +SLE E R N L++EI L ++L
Sbjct: 1460 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ETFKRENKNLQEEISDLTEQL 1518
Query: 153 KEE-KSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF-----KIF--QMNEERL 204
E K+ H ++ K + LE E L+S + EA+ + KI Q+ ++
Sbjct: 1519 GEGGKNVH--------ELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Query: 205 KIAIKDALNENSQLQESQKQLLQEA-------------------EVWKEQVSELNKQKVT 245
K I+ L E + E K+ Q V K+ +LN+ ++
Sbjct: 1571 KAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ 1630
Query: 246 FEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYL 305
HA ++ + + +K+L L KD L + + +D+L+ EN A +
Sbjct: 1631 LS----HANRMAAEAQKQVKSLQSLL---KDTQIQLDDAVRANDDLK-------ENIAIV 1676
Query: 306 DNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ 365
+ L A L+ L Q ++ E +E ++ L ++ SL
Sbjct: 1677 ER----------RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1726
Query: 366 SENTHFENENQKLQQKLKVMTELYQENEMKLHRKLT----VEENYRLEKE-----EKLSK 416
++ E++ +LQ +++ + + E K + +T + E + E++ E++ K
Sbjct: 1727 NQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1786
Query: 417 VDEK----ISHATEELETYR-KRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAE 471
E+ + H +E E K K ++LE + +G++ + +K+ ++ R +E
Sbjct: 1787 NMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSE 1846
Query: 472 RNLNDLRKENAHNRQKL 488
R + +L + +++ L
Sbjct: 1847 RRIKELTYQTEEDKKNL 1863
Score = 38.5 bits (88), Expect = 0.023
Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 16/161 (9%)
Query: 108 VESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 167
+E ++KD + E +L+ ++L + LE + LE EL+ E+ +++E + M
Sbjct: 1788 MEQTIKDLQHRLDEAEQIALKGGKKQLQK----LEARVRELEGELEAEQKRNAESVKGMR 1843
Query: 168 DISKRIQSL-----EDESKSLKSQ--VAEAKMTFKIFQMNEERLKIAIKDALNENSQLQE 220
+RI+ L ED+ L+ Q V + ++ K ++ E + L++ ++Q
Sbjct: 1844 KSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQH 1903
Query: 221 SQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 261
+ + A++ + QV++L + + A+Q ++D+E
Sbjct: 1904 ELDEAEERADIAESQVNKLRA-----KSRDIGAKQKMHDEE 1939
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 82.0 bits (201), Expect = 2e-15
Identities = 100/424 (23%), Positives = 199/424 (46%), Gaps = 62/424 (14%)
Query: 107 EVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELM 166
E E KD K + +E E++ R + +L +E L ++L+ E +E +E+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 167 ADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLL 226
A ++ + Q LE+ L+S+V E + +I Q +++++ I+D L E +E +Q L
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD-LEEQLDEEEGARQKL 969
Query: 227 QEAEVWKEQVSELNKQKVTFEDS-KVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDI 285
Q +KVT E K E++L ++ + K + E+ L M+D A +
Sbjct: 970 Q-------------LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKL-MEDRIAECSSQL 1015
Query: 286 TDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDK 345
+++ +++N A + N K+ + + L LK E R E++K
Sbjct: 1016 AEEE-------EKAKNLAKIRN------KQEVMISDLEERLKKEEKTR-------QELEK 1055
Query: 346 TKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVM------TELYQENEMKLHRK 399
K +L +LQ + A LQ++ + + K +++L+ L++ N +K+ R+
Sbjct: 1056 AKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRE 1115
Query: 400 L-----TVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT-----IHSY 449
L ++E++ EK + +K +++ +EELE + +LE+ L+ T + +
Sbjct: 1116 LQAQIAELQEDFESEKASR-NKAEKQKRDLSEELEALK---TELEDTLDTTAAQQELRTK 1171
Query: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLT---ETELKFEL-LEKDPYAL 505
+ Q ++ KKA + +N E + D+R+ +A ++L+ E +F+ LEK+ L
Sbjct: 1172 REQEVAELKKALEE--ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 506 DVPN 509
+ N
Sbjct: 1230 ETDN 1233
Score = 80.9 bits (198), Expect = 4e-15
Identities = 107/475 (22%), Positives = 197/475 (41%), Gaps = 65/475 (13%)
Query: 73 GREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCE 132
G +KL L + K+ E+ L++ + + E L + + +++ E +
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 133 KLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM 192
L + ++ E I LE+ LK+E+ E ++ + L+D+ L++Q+ E K+
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKL 1083
Query: 193 TFKIFQMNEERLKIAI----KDALNENSQLQ----------------ESQKQLLQEAEVW 232
EE L+ A+ + L++N+ L+ ES+K +AE
Sbjct: 1084 Q---LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
Query: 233 KEQVS-ELNKQKVTFEDS--KVHAEQVLNDK------------ESHIKTLTERLLKMKDW 277
K +S EL K ED+ A+Q L K E K ++ M+
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
Query: 278 AAMLGEDITD--DDNLELEMNSE-SENGAYLDNPPKGALKKLIHAAKLNA--SLKTLEGE 332
A E++++ + + N E ++ G DN K++ K + K L+ +
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
Query: 333 RNQIYIQLSEVDKTKEELTEHIKNLQTEQASL-------QSENTHFENENQKLQQKLKVM 385
+++ ++SE D+ + EL E LQ E ++ + + F + L+ +L+
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Query: 386 TELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT 445
EL QE + +KL + R +EEK S +++ EE E RK LE+
Sbjct: 1321 QELLQE---ETRQKLNLSSRIRQLEEEKNSLQEQQ-----EEEEEARK-------NLEKQ 1365
Query: 446 IHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 500
+ + Q Q+ +KK D+ + E L K+ Q+L E L ++ LEK
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK 1420
Score = 73.9 bits (180), Expect = 5e-13
Identities = 117/485 (24%), Positives = 205/485 (42%), Gaps = 43/485 (8%)
Query: 60 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESS--LKDASF 117
WR F V+ L V R+++ L EE K+ EK + V+ E E E + L++ +
Sbjct: 835 WRVFTKVKPLLQVTRQEE---ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI 891
Query: 118 EKEATEAQS-----LEATCEKLNRSNSELEDEILCLEKELKEEKSKH----SEQDELMAD 168
E +A++ E +L ELE+ + LE ++EE+ ++ +E+ ++ A
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 169 ISKRIQSL-EDESKSLKSQVAEAKMTFKIFQMNEERLKIA------IKDALNENSQLQES 221
I + L E+E K Q+ + KI +M EE L + IK+ ++ E
Sbjct: 952 IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 222 QKQLLQEAEVWKEQVSELNKQKVTFEDSKVH---AEQVLNDKESHIKTLTERLLKMKDWA 278
QL +E E K NKQ+V D + E+ + E + L ++D
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1071
Query: 279 AMLGEDITDDDNLELEMNSESENGAYL--DNPPKGALKKLIHAAKLNASLKTLEGERNQI 336
A L I D+ L+L E GA D+ L +L A + L+ +
Sbjct: 1072 AELQAQI-DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Query: 337 YIQLSEVDKTKEELTEHIKNLQTE-------QASLQSENTHFENENQKLQQKLKVMTELY 389
++ +K K +L+E ++ L+TE A+ Q T E E +L++ L+ T+ +
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190
Query: 390 --QENEMKLHRKLTVEE-NYRLEKEEK----LSKVDEKISHATEELETYRKRAKDLEEEL 442
Q +M+ +EE + +LE+ ++ L K + + +EL K + ++ E
Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAES 1250
Query: 443 ERTIHSYQGQIIS-HEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
E Q+ H K + + L AE+ + L+ E + L E E K KD
Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGDRLRVELAEK-ASKLQNELDNVSTLLEEAEKKGIKFAKD 1309
Query: 502 PYALD 506
+L+
Sbjct: 1310 AASLE 1314
Score = 73.6 bits (179), Expect = 7e-13
Identities = 107/485 (22%), Positives = 201/485 (41%), Gaps = 89/485 (18%)
Query: 85 LIEEKSKL---LEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSL--EATCEKLNRSNS 139
L E+ SKL L+ S + +E E ++ + AS E + + Q L E T +KLN S+
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
Query: 140 ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQM 199
++L+EEK+ EQ E + K +LE + +L+SQ+A+ K
Sbjct: 1338 I---------RQLEEEKNSLQEQQEEEEEARK---NLEKQVLALQSQLADTKKK------ 1379
Query: 200 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL-----------NKQKVTFED 248
+ D L L+E++K+LL++AE +++ E N+ + +D
Sbjct: 1380 --------VDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDD 1431
Query: 249 SKV---HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYL 305
V H QV ++ E K + L + K +A E+ D E E + L
Sbjct: 1432 LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE---RDRAEAEAREKETKALSL 1488
Query: 306 DNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ 365
+ AL+ + N K L + + +V K EL + + L+ + ++
Sbjct: 1489 ARALEEALEAKEEFERQN---KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
Query: 366 SENTHFENENQKLQQ-KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHA 424
++ E+E Q + KL++ + Q + + R L + EK+ L K ++
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNM-QAMKAQFERDLQTRDEQNEEKKRLLIK---QVREL 1601
Query: 425 TEELETYRKR--------------AKDLEEELE----------RTIHSYQGQIISHEKKA 460
ELE RK+ KDLE ++E + + Q Q+ ++++
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
Query: 461 HDN-------WLAARNAERNLNDLRKENAHNRQKLTETE--LKFELLEKDPYALDVPNTA 511
+ + ++ +E+ L L E +++L +E + E+D A ++ N+A
Sbjct: 1662 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Query: 512 FGRGS 516
G+ +
Sbjct: 1722 SGKSA 1726
Score = 68.9 bits (167), Expect = 2e-11
Identities = 85/411 (20%), Positives = 163/411 (39%), Gaps = 52/411 (12%)
Query: 100 QKEYEGYEVESSLKDASFEKEATEAQS--LEATCEKLNRSNSELEDEILCLEKELKEEKS 157
+KE + + +L++A KE E Q+ L A E L S ++ + LEK + +
Sbjct: 1480 EKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQ 1539
Query: 158 KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIF-----QMNEERLKIAIKDAL 212
+ E + ++ +Q+ ED L+ + K F+ + NEE+ ++ IK
Sbjct: 1540 QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR 1599
Query: 213 NENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLL 272
++L++ +KQ V+ K ++ +D + E ++ IK L +
Sbjct: 1600 ELEAELEDERKQRALA-------VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
Query: 273 KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGE 332
+MKD+ L E D + + ESE LK+LE E
Sbjct: 1653 QMKDYQRELEEARASRDEI-FAQSKESEK-----------------------KLKSLEAE 1688
Query: 333 RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQEN 392
Q+ +L+ ++ + + L E + S + +E ++L+ ++ + E +E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 393 EMKLH------RKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTI 446
+ + RK T++ + + +K +A ++LE K K +ELE +
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 447 HS-YQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 496
S ++ I + E K E L KE A + + TE K +
Sbjct: 1809 KSKFKATISALEAK-------IGQLEEQLEQEAKERAAANKLVRRTEKKLK 1852
Score = 66.6 bits (161), Expect = 8e-11
Identities = 90/444 (20%), Positives = 172/444 (38%), Gaps = 58/444 (13%)
Query: 82 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL 141
+ L E K KLL+ + + E + + + + E L + + S L
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNL 1446
Query: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 201
E + ++ L EEKS + E + E ++ SL + EA + F+
Sbjct: 1447 EKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQN 1506
Query: 202 ERLKIAIKDALNENS-------QLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHA- 253
++L+ ++D ++ +L++S++ L Q+ E + Q+ EL + ED+K+
Sbjct: 1507 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 1566
Query: 254 ------------------EQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEM 295
EQ K IK + E +++D + +E+++
Sbjct: 1567 VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDL 1626
Query: 296 NSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGE-------RNQIYIQLSEVDKTKE 348
+ A ++ K + + KL A +K + E R++I+ Q E +K +
Sbjct: 1627 ---KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLK 1683
Query: 349 ELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRL 408
L I LQ E AS + H E E +L ++ + ++E RL
Sbjct: 1684 SLEAEILQLQEELASSERARRHAEQERDELADEI---------TNSASGKSALLDEKRRL 1734
Query: 409 EKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAAR 468
E +I+ EELE + + L + +T + Q ++ E A + AA+
Sbjct: 1735 E---------ARIAQLEEELEEEQSNMELLNDRFRKT--TLQVDTLNAELAAERS--AAQ 1781
Query: 469 NAERNLNDLRKENAHNRQKLTETE 492
++ L ++N + KL E E
Sbjct: 1782 KSDNARQQLERQNKELKAKLQELE 1805
Score = 31.2 bits (69), Expect = 3.7
Identities = 41/200 (20%), Positives = 75/200 (37%), Gaps = 57/200 (28%)
Query: 83 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK--------------EATEAQSLE 128
S L++EK +L + + +++E E + L + F K E + AQ +
Sbjct: 1725 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD 1784
Query: 129 ATCEKLNRSNSEL----------------------EDEILCLEKELKEEKSKHSEQDELM 166
++L R N EL E +I LE++L++E + + ++L+
Sbjct: 1785 NARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLV 1844
Query: 167 ADISKRIQSL----EDES-----------------KSLKSQVAEAKMTFKIFQMNEERLK 205
K+++ + EDE K LK Q+ EA+ + +L+
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904
Query: 206 IAIKDALNENSQLQESQKQL 225
+ DA N L L
Sbjct: 1905 RELDDATEANEGLSREVSTL 1924
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 80.9 bits (198), Expect = 4e-15
Identities = 77/430 (17%), Positives = 187/430 (43%), Gaps = 34/430 (7%)
Query: 77 KLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNR 136
+L LS + +K K + KE + +E + E+ + L+ + +
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 223
Query: 137 SNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKI 196
SE++ + L+++L+ K +Q +L A+ + L+ S L++QV E ++ ++
Sbjct: 224 EKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRL 282
Query: 197 FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTF---EDSKVHA 253
Q EE++ + ++QE ++++ ++ E +EQ ++ +Q+ E+
Sbjct: 283 NQQQEEKM-------WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 254 EQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGAL 313
E+++ +KE I+ L E++ + E I + + E E E + +
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQ--------EKIREQE----EKRQEEEKIREQEKRQEQEA 383
Query: 314 KKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFEN 373
K K+ + + + + Q ++ + +E++ E + +Q ++ ++ +
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 374 ENQKL---QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELET 430
+ +K+ ++K++ E+ QE E K+ +E E+E K+ + +EK+ E++
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGE----QEGKMCEQEAKMQEQEEKMRRQEEKIRE 499
Query: 431 YRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTE 490
K+ ++ EE++ Q Q E+K + E + + ++ +K+ E
Sbjct: 500 QEKKIREQEEKIREQEEMMQEQ----EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 491 TELKFELLEK 500
E++ E+
Sbjct: 556 QEVRLRQQEE 565
Score = 71.6 bits (174), Expect = 3e-12
Identities = 65/381 (17%), Positives = 169/381 (44%), Gaps = 41/381 (10%)
Query: 85 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEA----QSLEATCEKLNRSNSE 140
L E+ +KL EK LV+ E E++ ++K+ + E + Q L+A + L +
Sbjct: 207 LKEKNAKLQEKLQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 141 LEDEILCLEKELKEEKSKHSEQDELM----ADISKRIQSLEDESKSLKSQVAEAKMTFKI 196
+ ++ +E + + +Q+E M I +R + ++++ + ++ Q + + ++
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 197 FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQV 256
EE+++ + + +++E ++++ ++ ++ +++ ++K+ ++ + E
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 257 LNDKESHIKTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGA 312
+ +E I+ E++ + M++ +GE E EM + E
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE------------ 432
Query: 313 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE 372
K K+ K + + +I Q + + +E++ E + ++A +Q +
Sbjct: 433 -KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 373 NENQKL----------QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIS 422
+ +K+ ++K++ E+ QE E K+ +E E+EEK+ + +EK+
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQEEKMR 547
Query: 423 HATEELETYRKRAKDLEEELE 443
E++ R + EE+++
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQ 568
Score = 61.6 bits (148), Expect = 3e-09
Identities = 75/380 (19%), Positives = 156/380 (41%), Gaps = 41/380 (10%)
Query: 135 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 194
N +N E C E E+K+ H Q+ L ++ ++Q++ + L Q E +M
Sbjct: 80 NGTNPETTTSGGCHSPE-DEQKASHQHQEALRRELEAQVQTI----RILTCQKTELQMAL 134
Query: 195 KIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAE 254
Q ++L+ +D + S+L +S K E E V+ K+ + +
Sbjct: 135 YYSQHAVKQLEGEARDLI---SRLHDSWK-FAGELEQALSAVATQKKKADRYIEELTKER 190
Query: 255 QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK 314
L+ E + T+T+ LK K+ + + + E+++N + LK
Sbjct: 191 DALS-LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE-------------LK 236
Query: 315 KLIHAAKLNASLKTLEGERNQIYIQLSEVDKT------KEELTEHIKNLQTE-----QAS 363
+ + AKL + L+ E + + +L V + EL + Q E +
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 296
Query: 364 LQSENTHFENENQKL---QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEK 420
+Q + + +K+ ++K++ E+ E E K+ R +E EKEEK+ +++EK
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR----QEEMMWEKEEKIRELEEK 352
Query: 421 ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 480
+ + E KR ++ + + + ++ E+K + R E + + ++
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 481 NAHNRQKLTETELKFELLEK 500
+K+ E E + + E+
Sbjct: 413 MGEQEEKMWEQEEEMQEQEE 432
Score = 59.7 bits (143), Expect = 1e-08
Identities = 79/406 (19%), Positives = 166/406 (40%), Gaps = 65/406 (16%)
Query: 100 QKEYEGYEVESSLKDA-SFEKEATEAQSLEATCEK-LNRSNSELEDEILCLEKELKEEKS 157
Q E E ++ S L D+ F E +A S AT +K +R EL E L EL
Sbjct: 143 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 202
Query: 158 KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKI-AIKDALNENS 216
E E A + +++Q +E E ++ V E K + ++ + ++ A D L +
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 217 QLQESQKQL-LQEAEVWKEQVSELNKQKVTFEDSKVHA-EQVLNDKESHIKTLTERLLKM 274
Q ++ Q ++E E+W ++++ ++K+ ++ K+ E+ + ++E I+ E++ +
Sbjct: 263 QSVSAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 275 KDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERN 334
+ EM E E + + +
Sbjct: 322 E------------------EMMWEKE--------------------------EKMRRQEE 337
Query: 335 QIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEM 394
++ + ++ + +E++ E K + E+ + E + + Q+ + K+ E +E E
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 395 KLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQII 454
K+ +E E+EEK+ + +EK+ EE++ ++ + EE++
Sbjct: 398 KIRE----QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIR----------- 442
Query: 455 SHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 500
EKK + R E + + ++ K+ E E K + E+
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Score = 53.9 bits (128), Expect = 5e-07
Identities = 58/318 (18%), Positives = 144/318 (45%), Gaps = 33/318 (10%)
Query: 68 SRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSL 127
+RL +E+K+ + E + K+ E+ ++++ E + ++ +EKE
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ---EEMMWEKE------- 329
Query: 128 EATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQV 187
EK+ R + ++ E++++E + K EQ+++ KR Q E + K Q
Sbjct: 330 ----EKMRRQEEMMWEK----EEKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQE 380
Query: 188 AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFE 247
EAKM + ++ E+ KI + +QE ++++ ++ E EQ E+ +Q E
Sbjct: 381 QEAKMWRQEEKIREQEEKIR-----EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ----E 431
Query: 248 DSKVHAEQVLNDKESHIKTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGA 303
+ E+ + ++E I+ E++ + M++ +GE E +M + E
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 304 YLDNPPKGALKKL-IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA 362
+ + KK+ K+ + ++ + +++ Q ++ + +E++ E + ++ ++
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 363 SLQSENTHFENENQKLQQ 380
++ + + +K+Q+
Sbjct: 552 KMREQEVRLRQQEEKMQE 569
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/194 (15%), Positives = 91/194 (46%), Gaps = 13/194 (6%)
Query: 59 LWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFE 118
+WR +R + E+K+ + E++ K+ E+ + ++ E + + E
Sbjct: 385 MWRQEEKIREQ-----EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 119 KEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI----Q 174
K + + + EK+ ++++ E+++ E++ K EQ+ M + +++ +
Sbjct: 440 KIREQEKKIREQEEKIREQEEMMQEQ----EEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Query: 175 SLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE 234
+ ++ K ++ Q + + ++ Q EE++ + + ++QE ++++ ++ E +E
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 235 QVSELNKQKVTFED 248
Q L +Q+ ++
Sbjct: 556 QEVRLRQQEEKMQE 569
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 80.9 bits (198), Expect = 4e-15
Identities = 109/461 (23%), Positives = 207/461 (44%), Gaps = 60/461 (13%)
Query: 86 IEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEI 145
++EK++LL+ S +V LKD + +E + QSLE + L+ + ELE++I
Sbjct: 2009 VKEKTELLQTLSS--------DVSELLKDKTHLQE--KLQSLEKDSQALSLTKCELENQI 2058
Query: 146 LCLEKE----LKEEKS---KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQ 198
L KE +KE +S + SE D ++SK +++ E +++ + +
Sbjct: 2059 AQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLR 2118
Query: 199 MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLN 258
E+L++ I+ + + E K+ +E + K++V L ++ E+++
Sbjct: 2119 RGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAE 2178
Query: 259 DKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIH 318
+ ++ ++TL ++ +M + D+ + + SE EN +G L +L
Sbjct: 2179 NSKAEVETLKTQIEEMARSLKVFELDL-------VTLRSEKENLTKQIQEKQGQLSEL-- 2229
Query: 319 AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEH-IKNLQTEQASL-----------QS 366
KL +S K+L E+ Q IQ+ E KT E+ ++ +K L A+L QS
Sbjct: 2230 -DKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288
Query: 367 ENTHFENENQ------KLQQKL-----KVMTELYQENEMKLHRKLTVEENYRLEKEEKLS 415
+ E E+Q KL+ +L K + L Q E + H L LE+E +++
Sbjct: 2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIA 2348
Query: 416 KVDEKISHATEELETYRKRAKDLEEELERTIHSYQG-----QIISHEKKAHDNWLAARNA 470
+ +++ HA E E + + L+ ++E S +G I EK+ N L +
Sbjct: 2349 RTNQE--HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNEL--QKE 2404
Query: 471 ERNLNDLRKENAHNRQKLTETEL-KFELLEKDPYALDVPNT 510
+ +++L N+ L E E K ++ EK A+++ T
Sbjct: 2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQT 2445
Score = 71.6 bits (174), Expect = 3e-12
Identities = 78/415 (18%), Positives = 190/415 (45%), Gaps = 38/415 (9%)
Query: 74 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 133
+E+ L+ + L EK++LL+ + Y ++SS+ E E + Q LE E+
Sbjct: 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNY--IVLQSSVNGLIQEVEDGK-QKLEKKDEE 2523
Query: 134 LNRSNSELEDEILCLEKELKEE------KSKHSEQDELMADISKRIQSLEDESKSLKSQV 187
++R ++++D+ + K + E K ++ E L ++ ++IQ L+ ++ SL+ +
Sbjct: 2524 ISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTL 2583
Query: 188 AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFE 247
+ ++K + E K+ + + +++ + +L +E ++ +EL +++++ E
Sbjct: 2584 EVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAEL-QEELSGE 2642
Query: 248 DSKVHAE-----QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDN----------LE 292
+++ E + + + +K LT ++K + +D + + L
Sbjct: 2643 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Query: 293 LEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTE 352
L + LD + ++ + KL + + L ++ +++ + +KEEL
Sbjct: 2703 LHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQK----LEIDLLKSSKEELNN 2758
Query: 353 HIK---NLQTEQASLQSENTHFEN----ENQKLQQKLKVMTELYQ--ENEMKLHRKLTVE 403
+K + E + +N + N EN++ Q K+K++ + + E E ++ +K +
Sbjct: 2759 SLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQ 2818
Query: 404 ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 458
EK++ + +D K+ T E++ ++ ++ +E + + Y +ISHEK
Sbjct: 2819 LQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEK 2873
Score = 66.6 bits (161), Expect = 8e-11
Identities = 100/468 (21%), Positives = 200/468 (42%), Gaps = 71/468 (15%)
Query: 88 EKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILC 147
E L K + + G E++ + E E Q + +L NS E+ +
Sbjct: 2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Query: 148 LEKELKEEKSKHSEQDELMA----DISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEER 203
E+E + K K S E++ ++++R+ +L ++ ++ K++ + ++ + +
Sbjct: 2425 KEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Query: 204 LKIAIKDALNENSQLQESQKQLLQEAEVWKEQV----SELNKQKVTFED--------SKV 251
L + +A N LQ S L+QE E K+++ E+++ K +D S+V
Sbjct: 2485 LLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQV 2544
Query: 252 HAEQVL------------NDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSES 299
E L + E I+ L + ++D +L + +N ELE+ ++
Sbjct: 2545 EGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN-ELEL-TKM 2602
Query: 300 ENGAYLDNPPKGALK------KLIHAAKLNASL-KTLEGERN----QIYIQLSEVDKTKE 348
+ ++++ K K ++ A+ A L + L GE+N ++ + L E+ +K+
Sbjct: 2603 DKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKD 2662
Query: 349 ELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQ---ENEMKLHRKLTVEEN 405
+L K L E + L+ + + + K++ YQ K H+ L ++ N
Sbjct: 2663 QL----KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Query: 406 YRLEKE-----EKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKA 460
+ E E EKL+ +E +S E++ + ++L L+ T QI+ KK
Sbjct: 2719 KQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATT-----QILEELKKT 2773
Query: 461 HDNWLAARNAERNLNDLRKEN--AHNRQKL-----TETELKFELLEKD 501
+ L + +N L+KEN A + KL + E + E+L+K+
Sbjct: 2774 KMDNL------KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2815
Score = 62.8 bits (151), Expect = 1e-09
Identities = 86/394 (21%), Positives = 166/394 (42%), Gaps = 66/394 (16%)
Query: 95 KFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKE 154
+ S ++ E E E+ +A E TE LE + N + I+CLE+EL
Sbjct: 1903 ELSRIRSEKASIEHEALYLEADLEVVQTEKLCLE-------KDNENKQKVIVCLEEELSV 1955
Query: 155 EKSKHSEQDELMADISKRIQSLEDESKSLKS----------------QVAEAKMTFKIFQ 198
S+ ++ + +SK+ +L+ S+ +K QVAEA++ K
Sbjct: 1956 VTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTEL 2015
Query: 199 MNEERLKIAIKDALNENSQLQESQKQLLQEAEV-------WKEQVSELNKQKVTFEDSKV 251
+ + L + + L + + LQE + L ++++ + Q+++LNK+K
Sbjct: 2016 L--QTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK-------- 2065
Query: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 311
E ++ + ES L+E + + + L + + L ++S E L
Sbjct: 2066 --ELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR---- 2119
Query: 312 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE-QAS------- 363
KL ++ E ++ I +L E ++ + L + ++NL+ E Q S
Sbjct: 2120 ------GIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELV 2173
Query: 364 -LQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYR---LEKEEKLSKVDE 419
L +EN+ E E K Q ++ M + E+ L + +EN EK+ +LS++D+
Sbjct: 2174 ILDAENSKAEVETLKTQ--IEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDK 2231
Query: 420 KISHATEELETYRKRAKDLEEELERTIHSYQGQI 453
+S LE + ++EE + + Q Q+
Sbjct: 2232 LLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL 2265
Score = 60.5 bits (145), Expect = 6e-09
Identities = 89/485 (18%), Positives = 188/485 (38%), Gaps = 83/485 (17%)
Query: 86 IEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEI 145
I+E L+K ++KE + + + +A+ +K+ + ++ + L R N L +
Sbjct: 20 IQELEGQLDK---LKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEIC 76
Query: 146 LCLEK-------ELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF---- 194
LEK EL+ ++S+ + Q+ + K+I+ LE E K KS++ ++
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSAD 136
Query: 195 ----------KIFQM-----------NEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 233
KIF E LK + E +L+ K L +
Sbjct: 137 VSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQT 196
Query: 234 EQVSELNKQKVTFEDSKVHAEQVLNDKE-SHIKTLTERLLKMKDWAAML--GEDITDDDN 290
+ +N + + + +K SH+ + ++R +D++A GE
Sbjct: 197 LPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSR 256
Query: 291 LELEMNSESENGAYLDNPPKGALKKLIHAA-------------KLNASLKTLEGERNQIY 337
L++ N ++ DN L + A +L K ++G+ N+
Sbjct: 257 STLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQ 316
Query: 338 IQLSEVDKTKEELTEHIKNL------------QTEQAS----------------LQSENT 369
+++K K EL E K L Q +QAS L +
Sbjct: 317 ELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ 376
Query: 370 HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELE 429
+ E+ L+QK+K + +QE + R + ++ + +L++ ++ + L+
Sbjct: 377 NAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436
Query: 430 TYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKEN----AHNR 485
+ ++++LE + ++ ++ E+ + + R++ +++KEN +H+
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 486 QKLTE 490
QK E
Sbjct: 497 QKARE 501
Score = 59.3 bits (142), Expect = 1e-08
Identities = 96/431 (22%), Positives = 167/431 (38%), Gaps = 61/431 (14%)
Query: 77 KLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEAT----EAQSLEATCE 132
K M + E S+ + K ++ E+ + EKE + ++ +A +
Sbjct: 869 KAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQ 928
Query: 133 KLNRSNSELED---EILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAE 189
+L +SN LED E+ L + L EK E +++ + I+ L E+ +LK A
Sbjct: 929 ELKKSNHLLEDSLKELQLLSETLSLEK---KEMSSIISLNKREIEELTQENGTLKEINAS 985
Query: 190 AKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQ----LLQEAEVWKEQVSELNKQKVT 245
E I + S+L + KQ LLQ E +L+++
Sbjct: 986 LNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKA 1045
Query: 246 FEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYL 305
++ E +LN+ S + L ++K+ A ++
Sbjct: 1046 AQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEF-------------------- 1085
Query: 306 DNPPKGALKKLIHAAKLNASLKTLEGERNQ-IYIQLSEVDKT-KEELTEHIKNLQTEQAS 363
L KL A ERNQ + ++L V + + E+T++ N ++E
Sbjct: 1086 -------LTKLAFAE-----------ERNQNLMLELETVQQALRSEMTDNQNNSKSEAGG 1127
Query: 364 LQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISH 423
L+ E + E K+Q K + +L QENE + T E LE E + V E+ S
Sbjct: 1128 LKQEIMTLKEEQNKMQ---KEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERES- 1183
Query: 424 ATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAH 483
E + K DLE + E ++ SY Q++ E + L + +E+ L+ E
Sbjct: 1184 --ERNQCNFKPQMDLEVK-EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQT 1240
Query: 484 NRQKLTETELK 494
R L + L+
Sbjct: 1241 IRGDLETSNLQ 1251
Score = 58.5 bits (140), Expect = 2e-08
Identities = 86/404 (21%), Positives = 169/404 (41%), Gaps = 44/404 (10%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 146
+E S LEK L + E +D S + +E +KL+++ E + +
Sbjct: 547 QENSLTLEKLKLAVADLE------KQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLS 600
Query: 147 CLE------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMN 200
LE +ELKEEK+ S ++ K + +E E ++L+S++ + K Q+
Sbjct: 601 ALELKKKEYEELKEEKTLFSCWK---SENEKLLTQMESEKENLQSKINHLETCLKTQQIK 657
Query: 201 E----ERLKIAIKDALNENSQLQESQKQLLQ---EAEVWKEQVSELNKQKVTFEDSKVHA 253
ER++ D N + +++ L E E K EL +QK F D K H
Sbjct: 658 SHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMEL-QQKAEFSDQK-HQ 715
Query: 254 EQVLNDKESHIKT--LTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN---------- 301
+++ N +KT LT ++ ++ +L +I D D ++++E E+
Sbjct: 716 KEIEN---MCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDA 772
Query: 302 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 361
+ + +L ++ S + GE+ + + SE ++ ++ LQ
Sbjct: 773 SLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRV 832
Query: 362 ASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKI 421
SL+ + N LQ++ + + ++ E E L + + +++ E +++SK+ E
Sbjct: 833 DSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDT 892
Query: 422 SH----ATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAH 461
S E L + K+L + L + + Q +I +K H
Sbjct: 893 SAHQNVVAETLSALENKEKEL-QLLNDKVETEQAEIQELKKSNH 935
Score = 56.6 bits (135), Expect = 8e-08
Identities = 83/407 (20%), Positives = 180/407 (44%), Gaps = 61/407 (14%)
Query: 107 EVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE---DEILCLEKELKEEKSKHSEQD 163
E + S K+++ + + SLE + E + NS+L+ +E++ ++ E++E K +
Sbjct: 817 EADQSPKNSAILQNRVD--SLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMH 874
Query: 164 E-LMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQ 222
+ +A+ S+RI L++++ + ++ VAE T + E+ L++ LN+ + ++++
Sbjct: 875 QSFVAETSQRISKLQEDTSAHQNVVAE---TLSALENKEKELQL-----LNDKVETEQAE 926
Query: 223 KQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERL-LKMKDWAAML 281
+ EL K EDS ++ L+E L L+ K+ ++++
Sbjct: 927 -------------IQELKKSNHLLEDSL-----------KELQLLSETLSLEKKEMSSII 962
Query: 282 GEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLS 341
+ + + L E + E A L+ ++K + S ER + +LS
Sbjct: 963 SLNKREIEELTQENGTLKEINASLNQEKMNLIQK-------SESFANYIDEREKSISELS 1015
Query: 342 EVDKTKEE---LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 398
D+ K+E L + + L + + +N KL+ L T L + + +L +
Sbjct: 1016 --DQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQ 1073
Query: 399 KLTVEENYRLEKEEKLSKV---DEKISHATEELETYRKRAKDLEEELERTIHSYQGQIIS 455
++E + E +E L+K+ +E+ + ELET ++ + + + S G +
Sbjct: 1074 ---LKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQ 1130
Query: 456 HEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDP 502
+ ++ +NDL +EN K+ +T+ + + LE +P
Sbjct: 1131 EIMTLKEE---QNKMQKEVNDLLQEN-EQLMKVMKTKHECQNLESEP 1173
Score = 49.7 bits (117), Expect = 1e-05
Identities = 91/448 (20%), Positives = 181/448 (40%), Gaps = 83/448 (18%)
Query: 81 MLSGLIEEKSKLLEKFSLVQKEYEGYEVE-----------------------------SS 111
+L L + +L K + ++ +G+E E +
Sbjct: 279 LLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNK 338
Query: 112 LKD------ASFEKEATEAQSLEATCEKL------NRSNSE-----LEDEILCLEKELKE 154
+D A +++ +T+ +LE +KL R N+E LE +I EKE +E
Sbjct: 339 CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQE 398
Query: 155 EKSKH--------SEQDELMADISKRIQS-------LEDESKSLKSQVAEAKMTFKIFQM 199
E S+ E ++ A +++ +Q L+ E L S + + + F+
Sbjct: 399 ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ 458
Query: 200 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 259
R + A + + + ++L+ S +++ +E + K + ++ E + +Q LN
Sbjct: 459 KLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQ 518
Query: 260 KESHIKTLTERLLKMKDWAAMLGEDITDDDN---LELEMNSESENGAYLDNPPKGALKKL 316
++ + + + + L E I +N LE + ++ D K+
Sbjct: 519 SQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKRE 578
Query: 317 IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN----THFE 372
H +LN L E E + LS ++ K+E E +K +T + +SEN T E
Sbjct: 579 HHIEQLNDKLSKTEKESKAL---LSALELKKKEY-EELKEEKTLFSCWKSENEKLLTQME 634
Query: 373 NENQKLQQKLKVMTELYQENEMKLH----RKLTVE---ENYRLEKEEKLSKVDEKISHAT 425
+E + LQ K+ + + ++K H R T+E EN +E + +D K +
Sbjct: 635 SEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSK----S 690
Query: 426 EELETYRKRAKDLEEELERTIHSYQGQI 453
E+ET + +L+++ E + +Q +I
Sbjct: 691 VEVETQKLAYMELQQKAEFSDQKHQKEI 718
Score = 47.0 bits (110), Expect = 7e-05
Identities = 91/440 (20%), Positives = 171/440 (38%), Gaps = 41/440 (9%)
Query: 74 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 133
REK ++ + +EK LL++ YE ++ K A + E E T
Sbjct: 1007 REKSISELSDQYKQEKLILLQRCEETGNAYE--DLSQKYKAAQEKNSKLECLLNECTSLC 1064
Query: 134 LNRSNSELEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLE----DESKSLKS 185
NR N ELE KE +E +K + +E LM ++ Q+L D + KS
Sbjct: 1065 ENRKN-ELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKS 1123
Query: 186 QVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ----EAEVWKEQVSELNK 241
+ K + + +++ + D L EN QL + K + E+E + V E
Sbjct: 1124 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERES 1183
Query: 242 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 301
++ + L KE + + +L++++ AML N EL++ ESE
Sbjct: 1184 ER---NQCNFKPQMDLEVKEISLDSYNAQLVQLE---AML-------RNKELKL-QESEK 1229
Query: 302 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 361
K L+ + + + L+ ++Q L + + EE ++I E
Sbjct: 1230 -------EKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEE--KYISG-PHEL 1279
Query: 362 ASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKI 421
++ Q++N H + Q KL + ++ + + + + +T + R E K+ E++
Sbjct: 1280 STSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEV 1339
Query: 422 SHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKEN 481
E++ + L EL I G+ + H LA + + L +
Sbjct: 1340 GKLLNEVKILNDDSGLLHGELVEDIPG--GEFGEQPNEQHPVSLAPLDESNSYEHLTLSD 1397
Query: 482 AHNRQKLTETELKFELLEKD 501
+ E + KF L+ +
Sbjct: 1398 KEVQMHFAELQEKFLSLQSE 1417
Score = 46.2 bits (108), Expect = 1e-04
Identities = 102/467 (21%), Positives = 179/467 (38%), Gaps = 82/467 (17%)
Query: 110 SSLKDASFEK---EATEAQSLEATCEKLNRSNSELEDEILC--------LEKELKEEKSK 158
SSL D+SF + E T SL + E +N DE+ C KE +K
Sbjct: 1488 SSLGDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAK 1547
Query: 159 HSEQDELMADISKRIQSLEDESKSLKSQVA----EAKMTFKIFQMNEERLKIAIKDALNE 214
E+ E + ++ + QSLE + ++SQ E + ++ + L K L+E
Sbjct: 1548 GVEELESLCEVYR--QSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSE 1605
Query: 215 NSQLQES------------------QKQLLQEAEVWKEQVSELNKQK-----VTFEDSKV 251
N Q Q+ +QL E EV + Q+ L+ + ED+
Sbjct: 1606 NEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAIQ 1665
Query: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSES-----------E 300
+ + + H TER K D + +D D NL++E +E+ E
Sbjct: 1666 GRNESCDISKEHTSETTERTPK-HDVHQICDKDAQQDLNLDIEKITETGAVKPTGECSGE 1724
Query: 301 NGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE 360
+ P G K + S + G L +D + E I NLQ
Sbjct: 1725 QSPDTNYEPPGEDKT--QGSSECISELSFSGPN-----ALVPMDFLGNQ--EDIHNLQLR 1775
Query: 361 QASLQSENTH----FENENQKLQQKLKVMTELYQENEMKLHRKLT-VEENYRLEK----- 410
+EN E+ ++K++ L M EL + ++ + +T +E LEK
Sbjct: 1776 VKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGEL 1835
Query: 411 EEKLSKVDEKISHAT-------EELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDN 463
+++ S + EK+ + + + +ET DLE +++ G ++ K +D+
Sbjct: 1836 KKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVA---KVNDS 1892
Query: 464 WLAA-RNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
W + E L+ +R E A + E E+++ + L+ N
Sbjct: 1893 WKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDN 1939
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 21/147 (14%)
Query: 309 PKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN 368
P AL+K+ +L L L+ E+ Q QL ++ ++ + ++N +TE
Sbjct: 13 PTRALQKI---QELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTE-------G 62
Query: 369 THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL 428
T+ + ENQ+L + + E ++ + K+ +L V+E+ +E +L+ ++I E+L
Sbjct: 63 TNLKRENQRLME----ICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQI----EKL 114
Query: 429 ETYRKRAKDLEEELERTIHSYQGQIIS 455
E KR K ELER+ + Q +S
Sbjct: 115 EQELKRCK---SELERSQQAAQSADVS 138
Score = 38.5 bits (88), Expect = 0.023
Identities = 72/383 (18%), Positives = 143/383 (37%), Gaps = 64/383 (16%)
Query: 140 ELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQM 199
ELE + L+K KE++ + + D L A + K+ Q +E+E + E + +I +
Sbjct: 22 ELEGQ---LDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICES 78
Query: 200 NEE-------RLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVH 252
E+ L++ + QL +KQ+ + + K SEL + + + + V
Sbjct: 79 LEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVS 138
Query: 253 AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGA 312
LN + K T L + ++ ED+ + N E+E
Sbjct: 139 ----LNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVE------------------ 176
Query: 313 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA-----SLQSE 367
+L A +K L Q + +T + T + +++ QA S Q E
Sbjct: 177 -----ERKRLEAEVKAL---------QAKKASQTLPQATMNHRDIARHQASSSVFSWQQE 222
Query: 368 NT--HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIS-HA 424
T H + +Q+ + + + + T++ +++ S D S H
Sbjct: 223 KTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIG---KRDANSSFFDNSSSPHL 279
Query: 425 TEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA-------ERNLNDL 477
++L+ + ++ ELE + ++ ++ K + L A E+ LN
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339
Query: 478 RKENAHNRQKLTETELKFELLEK 500
R E + + K+ LE+
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQ 362
Score = 30.0 bits (66), Expect = 8.4
Identities = 68/330 (20%), Positives = 127/330 (38%), Gaps = 27/330 (8%)
Query: 104 EGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEE--KSKHSE 161
E YE+ + L D+ E + E + LN L D+ L EL E+ + E
Sbjct: 1313 EKYELVTELNDSRSECITATRKMAEEVGKLLNEVKI-LNDDSGLLHGELVEDIPGGEFGE 1371
Query: 162 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQES 221
Q +S + + L E +M F Q L+ K +++ Q+
Sbjct: 1372 QPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSK 1431
Query: 222 QKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAML 281
+L + K + L+ F+ V E L +E + +L+ + + L
Sbjct: 1432 MSELQTYVDSLKAENLVLSTNLRNFQGDLVK-EMQLGLEEGLVPSLSSSCVPDSSSLSSL 1490
Query: 282 GED------ITDDDNLELEMNSE---SENGAYLDNPPKGALKK--LIHAAKLNASLKTLE 330
G+ + ++ L N E S N +D +L++ L +A K +E
Sbjct: 1491 GDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVE 1550
Query: 331 GERNQIYIQLSEVDKTKEELTEH--IKN---------LQTEQASLQSENTHFENENQKLQ 379
+ + ++K +E++ +KN L +E+ L + +EN++ Q
Sbjct: 1551 ELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQ 1610
Query: 380 QKLKVMTELYQENEMKLHRKLTVEENYRLE 409
QKL +T L E+++ +K T + + LE
Sbjct: 1611 QKLTSVT-LEMESKLAAEKKQTEQLSLELE 1639
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 80.5 bits (197), Expect = 5e-15
Identities = 88/427 (20%), Positives = 194/427 (45%), Gaps = 44/427 (10%)
Query: 74 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 133
+EK+++L+L + E+++K+ + L++ E + + L+ EK ++++L+ + EK
Sbjct: 264 KEKQVSLLLIQITEKENKMKDLTFLLE---ESRDKVNQLE----EKTKLQSENLKQSIEK 316
Query: 134 LNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMT 193
+ ELED + L++ + +K+ E+D +A + + E E++ +S A A +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKAL--EEDLQIATKTICQLTEEKETQMEESNKARAAHS 374
Query: 194 FKI--------------------FQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWK 233
F + + NE++LKI + ++S+L+E K L EV
Sbjct: 375 FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK-LTNNKEVEL 433
Query: 234 EQVSEL--NKQKVTFEDSKVH--AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDD 289
E++ ++ K+ + +E+ + AE++ ++ I L R ++ D L T +
Sbjct: 434 EELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQ 493
Query: 290 NLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD----- 344
E+ L+N + H KL+ K L E + + ++L
Sbjct: 494 YYSKEVKDLKTE---LENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINN 550
Query: 345 --KTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 402
K +E + + I+NLQ + L++E + E ++ + ++K + +EN L +++
Sbjct: 551 NKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVEN 610
Query: 403 EENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 462
+ Y E +++ + +K + +++L Y + LE ELE + +++K+ D
Sbjct: 611 KNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIED 670
Query: 463 NWLAARN 469
++ N
Sbjct: 671 KKISEEN 677
Score = 70.9 bits (172), Expect = 4e-12
Identities = 91/427 (21%), Positives = 184/427 (43%), Gaps = 36/427 (8%)
Query: 86 IEEKSKLLEKFSLVQ-------KEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSN 138
+E KL E + +Q KE E + SL ++ + + L E+
Sbjct: 237 LEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV 296
Query: 139 SELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQ 198
++LE++ + LK+ K + + DI +Q K+L+ + A T I Q
Sbjct: 297 NQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKT--ICQ 354
Query: 199 MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLN 258
+ EE+ +Q++ES K + V V+E + E+ +Q L
Sbjct: 355 LTEEK-----------ETQMEESNKARAAHSFV----VTEFETTVCSLEELLRTEQQRLE 399
Query: 259 DKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELE----MNSESENGAYLDNPPKGALK 314
E +K LT L K + + +T++ +ELE + E E Y + + +
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTK-LTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 315 KLIHA-AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFEN 373
+L +L L+ E E + + IQL+ + +++ ++ +K+L+TE + + +NT +
Sbjct: 459 ELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTS 518
Query: 374 ENQKLQQKLKVMTELYQENEMKLHRKLTVEE-NYRLEKEEKLSKVDEKISHATEELETYR 432
KL + K +T+ + ++M L K E+ N ++EE++ K E + +L R
Sbjct: 519 HCNKLSLENKELTQ--ETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL---R 573
Query: 433 KRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETE 492
+ + EEL++ + ++ E+ ++ N + + +L++EN ++K T
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 493 LKFELLE 499
+ + E
Sbjct: 634 KQLNVYE 640
Score = 57.8 bits (138), Expect = 4e-08
Identities = 95/430 (22%), Positives = 177/430 (41%), Gaps = 45/430 (10%)
Query: 12 LGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLY 71
L +L EL++ + L E + +N EL V+G L + + F + L
Sbjct: 405 LKILTMELQKKSSELEEMTKLTNNK---EVELEELKKVLGEKETLLYENKQFEKIAEELK 461
Query: 72 VGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATC 131
G E++L +L +E L + + + + Y E E E + L + C
Sbjct: 462 -GTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHC 520
Query: 132 EKLNRSNSELEDEILCLEKELK---EEKSKHSEQDELMADISKRIQSLEDESKSLKSQVA 188
KL+ N EL E + ELK E+ + + +Q+E M K+I++L++ L++++
Sbjct: 521 NKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERML---KQIENLQETETQLRNELE 577
Query: 189 EAKMTFK--------IFQMNEERLKIAIKDALNEN---SQLQESQKQLLQEAEVWKEQVS 237
+ K +EE K N+N +LQ+ K L ++ +Q++
Sbjct: 578 YVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLN 637
Query: 238 ----ELNKQKVTFEDSKVHAEQVLNDKESHI---KTLTERLLKMKDWAAMLGEDITDDDN 290
++NK ++ E +K ++ + + I K E LL+ + A ++ ++
Sbjct: 638 VYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV---K 694
Query: 291 LELEMNSESENG----AYLDNPPKGALKKLIHAAKLNASL-KTLEGERNQIYIQLS-EVD 344
L+ E++ ++ L K K+I L K+ E E++ + L E+
Sbjct: 695 LQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELS 754
Query: 345 KTKEELTEHIKNLQTEQASLQ------SENTHF--ENENQKLQQKLKVMTELYQENEMKL 396
K EL K L+ E+ + ENT E +++K Q L E+Y + + K
Sbjct: 755 NLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLDSKA 814
Query: 397 HRKLTVEENY 406
TV N+
Sbjct: 815 VPSQTVSRNF 824
Score = 40.8 bits (94), Expect = 0.005
Identities = 65/267 (24%), Positives = 117/267 (43%), Gaps = 44/267 (16%)
Query: 188 AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFE 247
AE +K+ E R K + L EN ++ E+Q++ +QE + E+VS L ++ E
Sbjct: 113 AEKIKKWKVSTEAELRQK---ESKLQENRKIIEAQRKAIQELQFGNEKVS-LKLEEGIQE 168
Query: 248 DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDN 307
+ + E N+ H+ L +K+ A E + E E Y+D
Sbjct: 169 NKDLIKE---NNATRHLCNL------LKETCARSAE-----KTKKYEYEREETRQVYMD- 213
Query: 308 PPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE----VDKTKEELTEHIKNLQTEQAS 363
++K+I A E R +++ +L E + ++E + I + + + +
Sbjct: 214 -LNNNIEKMITA--FEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSL 270
Query: 364 LQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISH 423
L + T EN K+K +T L +E+ K+++ +EE +L+ E L + EK H
Sbjct: 271 LLIQITEKEN-------KMKDLTFLLEESRDKVNQ---LEEKTKLQ-SENLKQSIEKQHH 319
Query: 424 ATEELETYR-------KRAKDLEEELE 443
T+ELE + K LEE+L+
Sbjct: 320 LTKELEDIKVSLQRSVSTQKALEEDLQ 346
Score = 38.1 bits (87), Expect = 0.031
Identities = 40/181 (22%), Positives = 78/181 (43%), Gaps = 24/181 (13%)
Query: 341 SEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLH--- 397
+E+ + + +L E+ K ++ ++ ++Q E + KL++ ++ +L +EN H
Sbjct: 125 AELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNATRHLCN 184
Query: 398 -------RKLTVEENYRLEKEE------KLSKVDEKISHATEELETYRKRAK-----DLE 439
R + Y E+EE L+ EK+ A EEL + ++ L+
Sbjct: 185 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLK 244
Query: 440 EELERTIH---SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 496
E+ E+ H Y+ +I EK+ + E + DL +R K+ + E K +
Sbjct: 245 EDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTK 304
Query: 497 L 497
L
Sbjct: 305 L 305
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 80.5 bits (197), Expect = 5e-15
Identities = 90/444 (20%), Positives = 180/444 (40%), Gaps = 67/444 (15%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEV----ESSLKDASFEKEATEAQSLEAT 130
EK++A M + K +L K +KE E V E + + EA E
Sbjct: 850 EKEMANMKEEFEKTKEELA-KTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 131 CEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 190
C++L ++ +LE +I KE + +++E+ A+++ + + LEDE LK + +
Sbjct: 909 CDQLIKTKIQLEAKI-------KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
Query: 191 KMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK 250
++T + + + +K+ E + L E+ +++L K+K +++
Sbjct: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDET--------------IAKLTKEKKALQEAH 1007
Query: 251 VHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPK 310
L +E + TLT+ +K+ E DD LE + E E +D
Sbjct: 1008 QQTLDDLQAEEDKVNTLTKAKIKL--------EQQVDD----LEGSLEQEKKIRMD---- 1051
Query: 311 GALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTH 370
L + + LEG+ +++ K++L E +K + E + LQS+
Sbjct: 1052 -----------LERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100
Query: 371 FENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLEKEEKLSKVDEKISHATEE 427
+ +LQ+K+K + +E E ++ + E R + +L ++ E++ A
Sbjct: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
Query: 428 LETYRKRAKDLEEELERTIHSYQGQIISHE------KKAHDNWLA-----ARNAERNLND 476
+ K E E ++ + + HE +K H + +A N +R
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
Query: 477 LRKENAHNRQKLTETELKFELLEK 500
L KE + + ++ + E + K
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSK 1244
Score = 79.3 bits (194), Expect = 1e-14
Identities = 98/437 (22%), Positives = 189/437 (43%), Gaps = 56/437 (12%)
Query: 82 LSGLIEEKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 139
L+ I E K + + ++K E E E++++L++A E E + L E LN+ S
Sbjct: 1516 LTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLE-LNQVKS 1574
Query: 140 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 181
E++ +I ++E+ + K H S Q L A+I R + +E +
Sbjct: 1575 EVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1634
Query: 182 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 241
AEA ++ Q + ++ + DAL L+E + + A + + ++ EL
Sbjct: 1635 HANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1694
Query: 242 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 301
E S+ AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1695 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARN 1754
Query: 302 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 358
+ A K + AA + LK + + +++ K+ L + +K+LQ
Sbjct: 1755 AE------EKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNLEQTVKDLQHRL 1801
Query: 359 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
EQ +L+ + + QKL+ +++ + E E++ +K VE L K E+ K
Sbjct: 1802 DEAEQLALKGG----KKQIQKLEARVREL-----EGEVESEQKRNVEAVKGLRKHERKVK 1852
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
++++ TEE R +DL ++L+ + SY+ Q E++++ N R + L
Sbjct: 1853 ---ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHEL-- 1907
Query: 477 LRKENAHNRQKLTETEL 493
E A R + E+++
Sbjct: 1908 ---EEAEERADIAESQV 1921
Score = 67.0 bits (162), Expect = 6e-11
Identities = 89/442 (20%), Positives = 177/442 (40%), Gaps = 53/442 (11%)
Query: 85 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDE 144
L E K KL ++ ++ E + + + + ++ E + L E+ N + + L+ +
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKK 1449
Query: 145 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 204
+K L E K K E +++ + ES+SL +++ FKI EE L
Sbjct: 1450 QRNFDKILAEWKQKCEE-------THAELEASQKESRSLSTEL------FKIKNAYEESL 1496
Query: 205 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 264
++ EN LQ+ L ++ +++ EL K K E K + L + E+ +
Sbjct: 1497 D-QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASL 1555
Query: 265 KTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAA 320
+ ++L+ + + + I + D E++ N + + L I +
Sbjct: 1556 EHEEGKILRIQLELNQVKSEVDRKIAEKDE---EIDQMKRNHIRIVESMQSTLDAEIRSR 1612
Query: 321 KLNASL-KTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFEN---ENQ 376
L K +EG+ N++ IQL+ ++ E ++N + QA L+ H ++ +
Sbjct: 1613 NDAIRLKKKMEGDLNEMEIQLNHANRM---AAEALRNYRNTQAILKDTQLHLDDALRSQE 1669
Query: 377 KLQQKLKVM---TELYQENEMKLHRKLTVEENYRLEKEEKL------------------- 414
L+++L ++ L Q +L L E R E++L
Sbjct: 1670 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729
Query: 415 --SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAER 472
K++ IS E+E + A++ EE+ ++ I + + KK D ++
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAI-TDAAMMAEELKKEQDTSAHLERMKK 1788
Query: 473 NLNDLRKENAHNRQKLTETELK 494
NL K+ H + + LK
Sbjct: 1789 NLEQTVKDLQHRLDEAEQLALK 1810
Score = 60.1 bits (144), Expect = 8e-09
Identities = 79/400 (19%), Positives = 174/400 (43%), Gaps = 54/400 (13%)
Query: 82 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL 141
+ L EE + L E + + KE + +L++A ++ + Q+ E L ++ +L
Sbjct: 979 VKNLTEEMAGLDETIAKLTKE------KKALQEAH-QQTLDDLQAEEDKVNTLTKAKIKL 1031
Query: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKS--QVAEAKMTFKIFQM 199
E ++ LE L++EK + + + ++ ++ + +++ Q + K+ K F+M
Sbjct: 1032 EQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEM 1091
Query: 200 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 259
+ + KI + AL QLQ+ K+L + ++ EL ++ S+ AE+ +D
Sbjct: 1092 SGLQSKIEDEQALG--MQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 260 KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE----------NGAYLDNPP 309
++ ++ERL E+ + ++EMN + E A L +
Sbjct: 1143 LSRELEEISERL-----------EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 310 KGALKKLIHA---AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQS 366
A + HA A+L + L+ + ++ +K K E+ I +L + ++
Sbjct: 1192 TAATLRKKHADSVAELGEQIDNLQRVKQKL-------EKEKSEMKMEIDDLASNMETVSK 1244
Query: 367 ENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEE-NYRLEKEEKLSKVDEK---IS 422
+ E + L+ +L + + +E + +L LT + + E E ++DEK +S
Sbjct: 1245 AKGNLEKMCRALEDQLSEI-KTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVS 1303
Query: 423 HATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 462
+ + + ++ ++L+ +LE I + + + HD
Sbjct: 1304 QLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHD 1343
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/421 (19%), Positives = 170/421 (40%), Gaps = 33/421 (7%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 134
EK + L E K+K E+ L+ + + + ++ E +L + +L
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLIN-DLTAQRARLQTESGEYSRQLDEKDTLVS---QL 1305
Query: 135 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 194
+R +I L+++L+EE S + L ++ + + Q A+A++
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYE--EEQEAKAELQR 1363
Query: 195 KIFQMNEERLKIAIK---DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
+ + N E + K DA+ +L+E++K+L Q + +E V +N + + E +K
Sbjct: 1364 AMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQ 1423
Query: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE-SENGAYLDNPPK 310
+ + D ++ + A L + + D + E + E A L+ K
Sbjct: 1424 RLQNEVEDLMIDVE-------RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQK 1476
Query: 311 GALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTH 370
+ L+ L ++ + QL + + + L + I +L TEQ + + H
Sbjct: 1477 -------ESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL-TEQIAEGGKRIH 1528
Query: 371 -FENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELE 429
E ++++Q+ + +E E L + +LE + S+VD KI+ EE++
Sbjct: 1529 ELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1588
Query: 430 TYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLT 489
++ R + S Q + + + +D + E +LN++ + H +
Sbjct: 1589 -------QMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
Query: 490 E 490
E
Sbjct: 1642 E 1642
Score = 31.6 bits (70), Expect = 2.9
Identities = 43/200 (21%), Positives = 81/200 (40%), Gaps = 43/200 (21%)
Query: 83 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE 142
+ LI K KL S +Q E E E+ + +K T+A + +K +++ LE
Sbjct: 1725 TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 143 DEILCLEKELKEEKSKHSEQDEL-MADISKRIQSLEDESKSLKSQVA------------- 188
LE+ +K+ + + E ++L + K+IQ LE + L+ +V
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGL 1844
Query: 189 ---EAKMTFKIFQMNEERLKIA-IKDALNENSQLQESQKQLLQEAE-------------- 230
E K+ +Q E+R I ++D +++ +S K+ +EAE
Sbjct: 1845 RKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQ 1904
Query: 231 -----------VWKEQVSEL 239
+ + QV++L
Sbjct: 1905 HELEEAEERADIAESQVNKL 1924
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 79.7 bits (195), Expect = 9e-15
Identities = 91/443 (20%), Positives = 185/443 (41%), Gaps = 65/443 (14%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 134
EK++A M EE K+ K L + E + E+E + EK + Q ++A E L
Sbjct: 852 EKEMATMK----EEFQKI--KDELAKSEAKRKELEEKMVTLLKEKNDLQLQ-VQAEAEGL 904
Query: 135 NRSNSELEDEI---LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 191
+ + I + LE ++KE + +++E+ A+++ + + LEDE LK + + +
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 192 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
+T + + + +K+ E + L E+ +++L K+K +++
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDET--------------IAKLTKEKKALQEAHQ 1010
Query: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 311
L +E + TLT+ +K+ E DD LE + E E +D
Sbjct: 1011 QTLDDLQAEEDKVNTLTKAKIKL--------EQQVDD----LEGSLEQEKKLRMD----- 1053
Query: 312 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHF 371
L + + LEG+ + +++ K++L E +K + E ++LQS+
Sbjct: 1054 ----------LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 372 ENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLEKEEKLSKVDEKISHATEEL 428
+ +LQ+K+K + +E E ++ + E R + +L ++ E++ A
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
Query: 429 ETYRKRAKDLEEELERTIHSYQGQIISHE------KKAHDNWLA-----ARNAERNLNDL 477
+ K E E ++ + + HE +K H + +A N +R L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 478 RKENAHNRQKLTETELKFELLEK 500
KE + + ++ + E + K
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSK 1246
Score = 77.8 bits (190), Expect = 3e-14
Identities = 97/437 (22%), Positives = 188/437 (43%), Gaps = 56/437 (12%)
Query: 82 LSGLIEEKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 139
L+ I E K + + ++K E E E++++L++A E E + L E LN+ S
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLE-LNQVKS 1576
Query: 140 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 181
E++ +I ++E+ + K H S Q L A+I R + +E +
Sbjct: 1577 EVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Query: 182 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 241
AEA ++ Q + +I + DAL L+E + + A + + ++ EL
Sbjct: 1637 HANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1696
Query: 242 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 301
E S+ AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1697 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARN 1756
Query: 302 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 358
+ A K + AA + LK + + +++ K+ + + +K+LQ
Sbjct: 1757 A------EEKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNMEQTVKDLQLRL 1803
Query: 359 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
EQ +L+ + + QKL+ +++ + E E++ +K E L K E+ K
Sbjct: 1804 DEAEQLALKGG----KKQIQKLEARVREL-----EGEVESEQKRNAEAVKGLRKHERRVK 1854
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
++++ TEE R +DL ++L+ + SY+ Q E++++ N R + L
Sbjct: 1855 ---ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL-- 1909
Query: 477 LRKENAHNRQKLTETEL 493
E A R + E+++
Sbjct: 1910 ---EEAEERADIAESQV 1923
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/434 (19%), Positives = 168/434 (38%), Gaps = 74/434 (17%)
Query: 118 EKEATEAQ----SLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 173
EKE +E + L + E ++++ LE LE +L E KSK EQ L+ D++ +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 174 QSLE----------DESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQK 223
L+ DE ++L SQ++ K F E LK +++ + + L + +
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFT---QQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 224 QLLQEAEVWKEQVSELNKQKVTF-----------------------------EDSKVHAE 254
+ ++ +EQ E + K E++K
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 255 QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK 314
Q L E H++ + + ++ L ++ D L L++ + A LD + K
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED---LMLDVERTNAACAALDKKQRNFDK 1457
Query: 315 KLIH----AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENT- 369
L + +A L+ + E + +L ++ EE + ++ L+ E +LQ E +
Sbjct: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
Query: 370 -------------HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
E ++++Q+ + +E E L + +LE + S+
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
VD KI+ EE++ L+ R + S Q + + + +D + E +LN+
Sbjct: 1578 VDRKIAEKDEEID-------QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNE 1630
Query: 477 LRKENAHNRQKLTE 490
+ + H + E
Sbjct: 1631 MEIQLNHANRMAAE 1644
Score = 65.1 bits (157), Expect = 2e-10
Identities = 79/415 (19%), Positives = 162/415 (39%), Gaps = 21/415 (5%)
Query: 83 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE-ATEAQSLEATCEKLNRSNSEL 141
S IE K +F ++++ E ++ A+ K+ A L + L R +L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 201
E E ++ E+ + S + ++ K ++LED+ LKS+ E +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 202 ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 261
RL+ + + + + QL + + + +Q+ EL +Q +K L
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
Query: 262 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 321
L E+ + ++ A L ++ + + ++ E A KK K
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK-----K 1398
Query: 322 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 381
L L+ E + + + ++KTK+ L +++L + ++ N ++K +
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQRNF 1455
Query: 382 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 441
K++ E Q+ E + H +L + +L K+ + ++LET ++ K+L++E
Sbjct: 1456 DKILAEWKQKCE-ETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Query: 442 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 496
I QI K+ H+ E+ + +E + L E E E
Sbjct: 1515 ----ISDLTEQIAEGGKRIHE-------LEKIKKQVEQEKCELQAALEEAEASLE 1558
Score = 31.6 bits (70), Expect = 2.9
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 108 VESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 167
+E ++KD + E +L+ +++ + LE + LE E++ E+ +++E + +
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 168 DISKRIQSL-----EDESKSLKSQVAEAKMTFKI--FQMNEERLKIAIKDALNENSQLQE 220
+R++ L ED L+ Q K+ K+ ++ E + L + +LQ
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 221 SQKQLLQEAEVWKEQVSEL 239
++ + A++ + QV++L
Sbjct: 1908 ELEEAEERADIAESQVNKL 1926
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 79.7 bits (195), Expect = 9e-15
Identities = 91/443 (20%), Positives = 185/443 (41%), Gaps = 65/443 (14%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 134
EK++A M EE K+ K L + E + E+E + EK + Q ++A E L
Sbjct: 852 EKEMATMK----EEFQKI--KDELAKSEAKRKELEEKMVTLLKEKNDLQLQ-VQAEAEGL 904
Query: 135 NRSNSELEDEI---LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 191
+ + I + LE ++KE + +++E+ A+++ + + LEDE LK + + +
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 192 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
+T + + + +K+ E + L E+ +++L K+K +++
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDET--------------IAKLTKEKKALQEAHQ 1010
Query: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 311
L +E + TLT+ +K+ E DD LE + E E +D
Sbjct: 1011 QTLDDLQAEEDKVNTLTKAKIKL--------EQQVDD----LEGSLEQEKKLRMD----- 1053
Query: 312 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHF 371
L + + LEG+ + +++ K++L E +K + E ++LQS+
Sbjct: 1054 ----------LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 372 ENENQKLQQKLKVMTELYQENEMKLHRKLTVE---ENYRLEKEEKLSKVDEKISHATEEL 428
+ +LQ+K+K + +E E ++ + E R + +L ++ E++ A
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
Query: 429 ETYRKRAKDLEEELERTIHSYQGQIISHE------KKAHDNWLA-----ARNAERNLNDL 477
+ K E E ++ + + HE +K H + +A N +R L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 478 RKENAHNRQKLTETELKFELLEK 500
KE + + ++ + E + K
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSK 1246
Score = 77.8 bits (190), Expect = 3e-14
Identities = 97/437 (22%), Positives = 188/437 (43%), Gaps = 56/437 (12%)
Query: 82 LSGLIEEKSKLLEKFSLVQK--EYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 139
L+ I E K + + ++K E E E++++L++A E E + L E LN+ S
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLE-LNQVKS 1576
Query: 140 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 181
E++ +I ++E+ + K H S Q L A+I R + +E +
Sbjct: 1577 EVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Query: 182 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 241
AEA ++ Q + +I + DAL L+E + + A + + ++ EL
Sbjct: 1637 HANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1696
Query: 242 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 301
E S+ AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1697 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARN 1756
Query: 302 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 358
+ A K + AA + LK + + +++ K+ + + +K+LQ
Sbjct: 1757 A------EEKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNMEQTVKDLQLRL 1803
Query: 359 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
EQ +L+ + + QKL+ +++ + E E++ +K E L K E+ K
Sbjct: 1804 DEAEQLALKGG----KKQIQKLEARVREL-----EGEVESEQKRNAEAVKGLRKHERRVK 1854
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
++++ TEE R +DL ++L+ + SY+ Q E++++ N R + L
Sbjct: 1855 ---ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL-- 1909
Query: 477 LRKENAHNRQKLTETEL 493
E A R + E+++
Sbjct: 1910 ---EEAEERADIAESQV 1923
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/434 (19%), Positives = 168/434 (38%), Gaps = 74/434 (17%)
Query: 118 EKEATEAQ----SLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRI 173
EKE +E + L + E ++++ LE LE +L E KSK EQ L+ D++ +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 174 QSLE----------DESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQK 223
L+ DE ++L SQ++ K F E LK +++ + + L + +
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFT---QQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 224 QLLQEAEVWKEQVSELNKQKVTF-----------------------------EDSKVHAE 254
+ ++ +EQ E + K E++K
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 255 QVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALK 314
Q L E H++ + + ++ L ++ D L L++ + A LD + K
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED---LMLDVERTNAACAALDKKQRNFDK 1457
Query: 315 KLIH----AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENT- 369
L + +A L+ + E + +L ++ EE + ++ L+ E +LQ E +
Sbjct: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
Query: 370 -------------HFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
E ++++Q+ + +E E L + +LE + S+
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
VD KI+ EE++ L+ R + S Q + + + +D + E +LN+
Sbjct: 1578 VDRKIAEKDEEID-------QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNE 1630
Query: 477 LRKENAHNRQKLTE 490
+ + H + E
Sbjct: 1631 MEIQLNHANRMAAE 1644
Score = 65.1 bits (157), Expect = 2e-10
Identities = 79/415 (19%), Positives = 162/415 (39%), Gaps = 21/415 (5%)
Query: 83 SGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE-ATEAQSLEATCEKLNRSNSEL 141
S IE K +F ++++ E ++ A+ K+ A L + L R +L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 201
E E ++ E+ + S + ++ K ++LED+ LKS+ E +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 202 ERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 261
RL+ + + + + QL + + + +Q+ EL +Q +K L
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
Query: 262 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 321
L E+ + ++ A L ++ + + ++ E A KK K
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK-----K 1398
Query: 322 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 381
L L+ E + + + ++KTK+ L +++L + ++ N ++K +
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQRNF 1455
Query: 382 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 441
K++ E Q+ E + H +L + +L K+ + ++LET ++ K+L++E
Sbjct: 1456 DKILAEWKQKCE-ETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Query: 442 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 496
I QI K+ H+ E+ + +E + L E E E
Sbjct: 1515 ----ISDLTEQIAEGGKRIHE-------LEKIKKQVEQEKCELQAALEEAEASLE 1558
Score = 31.6 bits (70), Expect = 2.9
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 108 VESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMA 167
+E ++KD + E +L+ +++ + LE + LE E++ E+ +++E + +
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 168 DISKRIQSL-----EDESKSLKSQVAEAKMTFKI--FQMNEERLKIAIKDALNENSQLQE 220
+R++ L ED L+ Q K+ K+ ++ E + L + +LQ
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 221 SQKQLLQEAEVWKEQVSEL 239
++ + A++ + QV++L
Sbjct: 1908 ELEEAEERADIAESQVNKL 1926
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 79.3 bits (194), Expect = 1e-14
Identities = 97/438 (22%), Positives = 192/438 (43%), Gaps = 46/438 (10%)
Query: 86 IEEKSKLLEKFSLVQKEYEG-YEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDE 144
+E+K K ++ +K Y E +A ++ T+A SL E+ +ELE
Sbjct: 1439 LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERL 1498
Query: 145 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 204
E+++ S + + + ++ K ++LE + + +K+Q+ E + + + + RL
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 205 KIAI--------KDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQV 256
++ + +D + Q +E +KQL+++ + ++ + KQ+ ++ E
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMD 1618
Query: 257 LNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKL 316
L D E+HI + K +D E I L+ +M LD+ + L
Sbjct: 1619 LKDLEAHIDSAN----KNRD------EAIKQLRKLQAQMKDCMRE---LDDTRASREEIL 1665
Query: 317 IHAAKLNASLKTLEGERNQIYIQLSEVDKTK-------EELTEHIKNLQTEQASLQSENT 369
A + LK++E E Q+ +L+ ++ K +EL + I N + A E
Sbjct: 1666 AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKR 1725
Query: 370 HFENENQKLQQKLKVM---TELYQENEMKLHRKLT-VEENYRLEKEEKLSKVDEKISHAT 425
E +L+++L+ TEL + K + ++ + + LE+ +K +A
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHA-----QKNENAR 1780
Query: 426 EELETYRKRAKDLEEELERTIHS-YQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHN 484
++LE K K +E+E T+ S Y+ I + E K A+ E+ N+ ++ A
Sbjct: 1781 QQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKERQAAC 1834
Query: 485 RQ-KLTETELKFELLEKD 501
+Q + TE +LK LL+ D
Sbjct: 1835 KQVRRTEKKLKDVLLQVD 1852
Score = 73.9 bits (180), Expect = 5e-13
Identities = 98/440 (22%), Positives = 199/440 (45%), Gaps = 74/440 (16%)
Query: 60 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK 119
WR F V+ L V R+++ ++ KE E +V K + E
Sbjct: 828 WRLFTKVKPLLQVSRQEE-------------------EMMAKEEELVKVRE--KQLAAEN 866
Query: 120 EATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
TE ++L+ S+L E L L+++L+ E +E +EL A ++ + Q LE+
Sbjct: 867 RLTEMETLQ----------SQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKE-QVSE 238
L+++V E + + Q +++++ I++ L E + +ES +Q LQ +V E ++ +
Sbjct: 917 CHDLEARVEEEEERCQHLQAEKKKMQQNIQE-LEEQLEEEESARQKLQLEKVTTEAKLKK 975
Query: 239 LNKQKVTFEDSK---VHAEQVLNDKESHIKT-LTERLLKMKDWAAMLGEDITDDDNLELE 294
L ++++ ED +++L D+ + T LTE K K A + + +LE
Sbjct: 976 LEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEER 1035
Query: 295 MNSESENGAYLDNPPK-------------GALKKLIHAAK---------LNASLKTLEGE 332
+ E + L+ + L+ I K L A+L +E E
Sbjct: 1036 LRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEE 1095
Query: 333 RNQIYIQLSEVDKTKEELTEHIKNLQTEQAS---LQSENTHFENENQKLQQKLK------ 383
Q + L ++ + + +++E ++L++E+AS + + E + L+ +L+
Sbjct: 1096 AAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDST 1155
Query: 384 -VMTELYQENEMKLH-RKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 441
EL + E +++ K T+EE + E ++ ++ +K S A EEL ++ K ++
Sbjct: 1156 AAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 442 LER---TIHSYQGQIISHEK 458
LE+ T+ + +G++ + K
Sbjct: 1215 LEKAKQTLENERGELANEVK 1234
Score = 72.8 bits (177), Expect = 1e-12
Identities = 75/415 (18%), Positives = 176/415 (42%), Gaps = 59/415 (14%)
Query: 88 EKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILC 147
+ + L ++ + +Q + +++ + K+ + + A + ELE +I
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISE 1115
Query: 148 LEKELKEEKSKHSEQDELMADISKRIQSLEDESK-SLKSQVAEAKMTFKIFQMNEERLKI 206
L+++L+ E++ ++ ++ D+ + +++L+ E + +L S A+ ++ K Q K
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKT 1175
Query: 207 AIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKT 266
++A +Q+QE +++ Q E EQ+ + + K E +K E + + +K
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 267 LTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASL 326
L L+ +SE+
Sbjct: 1236 L-------------------------LQGKGDSEH-----------------------KR 1247
Query: 327 KTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMT 386
K +E + ++ ++ +E ++ + EL + + LQ E ++ + ++++ KL + +
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL- 1306
Query: 387 ELYQENEMKLHRKLTVEEN-YRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT 445
E++++ ++L EEN +L KL +V+++ + E+LE ++ + LE+
Sbjct: 1307 ----ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE----EEEEAKHNLEKQ 1358
Query: 446 IHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEK 500
I + Q+ +KK D+ AE L+K+ Q+ E ++ LEK
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK 1413
Score = 71.2 bits (173), Expect = 3e-12
Identities = 98/495 (19%), Positives = 196/495 (39%), Gaps = 36/495 (7%)
Query: 72 VGREKKLALMLSGLIEEKSKLLEKF--SLVQKEYEGYEVESSLKDASFEKEATEAQSLEA 129
+ E K+ L G E K K +E L K EG V + L D K E ++
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD-KVTKLQVELDNVTG 1287
Query: 130 TCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAE 189
+ + +S+L + LE +L++ + E++ +S +++ +EDE S + Q+ E
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEE 1347
Query: 190 AKMTFKIFQMNEERLKIAIKDA---LNENSQLQESQKQLLQEAEVWKEQVSELNKQKVT- 245
+ + L + D + ++ E+ +++ ++ + E +S+ +++KV
Sbjct: 1348 EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAA 1407
Query: 246 ---FEDSKVHAEQVLNDK----ESHIKTLTERLLKMKDWAAMLGEDIT-------DDDNL 291
E +K +Q L+D + ++ K K + +L E+ T + D
Sbjct: 1408 YDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA 1467
Query: 292 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELT 351
E E + L + A+++ +LN +T E + +V K+ EL
Sbjct: 1468 EAEAREKETKALSLARALEEAMEQKAELERLNKQFRT---EMEDLMSSKDDVGKSVHELE 1524
Query: 352 EHIKNLQTEQASLQSENTHFENENQKLQQ-KLKVMTELYQENEMKLHRKLTVEENYRLEK 410
+ + L+ + ++++ E+E Q + KL++ L Q + + R L + EK
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL-QAMKAQFERDLQGRDEQSEEK 1583
Query: 411 EEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA 470
+++L + ++ E+ R A ++LE + + I S K + R
Sbjct: 1584 KKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKL 1643
Query: 471 E-------RNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPL 523
+ R L+D R + E E K + +E + L A R R
Sbjct: 1644 QAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQER 1703
Query: 524 DH---QITNERGESS 535
D +I N G+ +
Sbjct: 1704 DELADEIANSSGKGA 1718
Score = 62.4 bits (150), Expect = 2e-09
Identities = 77/372 (20%), Positives = 154/372 (41%), Gaps = 44/372 (11%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 146
E+K +L+ + ++ E E + S+ A+ +K + + LEA + N++ E ++
Sbjct: 1582 EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLR 1641
Query: 147 CLEKELK----EEKSKHSEQDELMADIS---KRIQSLEDESKSLKSQVAEAKMTFKIFQM 199
L+ ++K E + ++E++A K+++S+E E L+ ++A A+ + Q
Sbjct: 1642 KLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQ 1701
Query: 200 NEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 259
+ L I ++ + + E +++L EA + E+ L +
Sbjct: 1702 ERDELADEIANSSGKGALALEEKRRL--EARI-------------------AQLEEELEE 1740
Query: 260 KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENG-AYLDNPPKGALKKLIH 318
++ + + + +RL K A + + I D NLE ++EN L+ K KL
Sbjct: 1741 EQGNTELINDRLKK----ANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE 1796
Query: 319 -----AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE-QASLQSENTHFE 372
+K AS+ LE + Q+ QL K ++ + ++ + + + L +
Sbjct: 1797 MEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERR 1856
Query: 373 NENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYR 432
N Q Q K T L Q L R+L E K+ ++ ATE +
Sbjct: 1857 NAEQYKDQADKASTRLKQ-----LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1911
Query: 433 KRAKDLEEELER 444
+ L+ +L R
Sbjct: 1912 REVSSLKNKLRR 1923
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 79.3 bits (194), Expect = 1e-14
Identities = 100/466 (21%), Positives = 207/466 (44%), Gaps = 77/466 (16%)
Query: 67 RSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGY---------EVESSLKDASF 117
++R+ V +E AL L I E+S+ L++ ++EY+ ++E L A
Sbjct: 523 QARMEVSQEDDKALQLLHDIREQSRKLQEIK--EQEYQAQVEEMRLMMNQLEEDLVSARR 580
Query: 118 EKEATEAQSLEA--TCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQS 175
+ E++ E+ E+ R +E + ++L + + K E ++++ +++ A+ +IQ
Sbjct: 581 RSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQE 640
Query: 176 LEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQ 235
L+++ + EA + + +ER + ++ N + +K+L+ EAE +E+
Sbjct: 641 LQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLV-EAEELEEK 699
Query: 236 VSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEM 295
E +V+ + +VH +Q E IK L ++ K D+ D + LE M
Sbjct: 700 HRE---AQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKK----------DLADKETLE-NM 745
Query: 296 NSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD----------- 344
E A+ K +I+A +++ +++LE Q ++LSE +
Sbjct: 746 MQRHEEEAHEKGKILSEQKAMINA--MDSKIRSLE----QRIVELSEANKLAANSSLFTQ 799
Query: 345 ---KTKEELTEHIKN----LQTEQASLQSENTHFENENQK--------------LQQKLK 383
K +EE+ ++ L+T+ L+++N E + +K L+ +L+
Sbjct: 800 RNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLR 859
Query: 384 VMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELE 443
++ ++E +++L R+LT + E+E +L+ + A LE+ ++AK EE
Sbjct: 860 EVSLEHEEQKLELKRQLTELQLSLQERESQLT----ALQAARAALESQLRQAKTELEETT 915
Query: 444 RTIHSYQGQIISHEKKAHDNWLAARNA-------ERNLNDLRKENA 482
+ +H + + A RN+ E LN L ++NA
Sbjct: 916 AEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNA 961
Score = 59.7 bits (143), Expect = 1e-08
Identities = 80/385 (20%), Positives = 167/385 (43%), Gaps = 18/385 (4%)
Query: 79 ALMLSGLIEEKSKLLEKFSLVQKEYEG---YEVESSLKDASFEKEATEAQSLEATCEKLN 135
A + S L + K++L E + ++E + + E K + T LE +L
Sbjct: 898 AALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLT 957
Query: 136 RSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 195
N+EL ++ L K+L E + E +L +++ + + + L SQ +
Sbjct: 958 EDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKT 1017
Query: 196 IFQMNEERLK--IAIKDALNENSQLQESQKQLL-QEAEVWKEQVSELNKQKVTFEDSKVH 252
M EE++ A+ D L E + E+ + +L E ++ +V EL + T + S+
Sbjct: 1018 TCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRAR 1077
Query: 253 AEQVLNDKESHIK-TLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 311
A+Q + + ++ + E ++ L E ++L ++N + A L+ +
Sbjct: 1078 ADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARS 1137
Query: 312 ALKKLIHAAKLNASLKTLEGE-RNQIYIQLSEVDKTKEELTEHIKN---LQTEQASL--Q 365
+KL +L L + + + Q+ +Q + + + + L E + L+TE++ L Q
Sbjct: 1138 LQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQ 1197
Query: 366 SENTH--FENENQKLQQKLKVMTELYQENEMKLHRKLTVEE---NYRLEKEEKLSKVDEK 420
EN + +E K++ + T+L + K+ + ++ + R E ++V +
Sbjct: 1198 LENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQ 1257
Query: 421 ISHATEELETYRKRAKDLEEELERT 445
+ LE + R +LEE L++T
Sbjct: 1258 YNELKLALEKEKARCAELEEALQKT 1282
Score = 57.0 bits (136), Expect = 6e-08
Identities = 95/438 (21%), Positives = 182/438 (41%), Gaps = 77/438 (17%)
Query: 86 IEEKSKLLEKFSL-VQKEYEGYE-VESSLKDASFEKEAT----EAQS--LEATCEKLNRS 137
+ E +KL SL Q+ + E + S L+ F E EAQ+ LE EK++
Sbjct: 784 LSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQ 843
Query: 138 NSELEDEILCLEKELKEEKSKHSEQD--------ELMADISKR---IQSLEDESKSLKSQ 186
+ ++ +L LE L+E +H EQ EL + +R + +L+ +L+SQ
Sbjct: 844 DHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQ 903
Query: 187 VAEAKMTFK---------IFQMNEERLKIAIK-DALNEN----SQLQESQKQLLQE-AEV 231
+ +AK + I + R +I K DAL + + L+E QL ++ AE+
Sbjct: 904 LRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAEL 963
Query: 232 ---------WKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLG 282
++ S N + V H + + ++E + + + + +K ML
Sbjct: 964 NNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLE 1023
Query: 283 EDITD-----DDNLELEMNSESENGAYLDNPPK-----GALKKLIHAAK---------LN 323
E + D D+ LE E E+ D + L++++ K +
Sbjct: 1024 EQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRIT 1083
Query: 324 ASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLK 383
S + +E + ++ + + +E ++L + L+ ++ E + LQQKL+
Sbjct: 1084 ESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLE 1143
Query: 384 VMTELYQ---ENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 440
EL Q E + KL +++ +++N+ + ++ + + A + + + DLE
Sbjct: 1144 TERELKQRLLEEQAKLQQQMDLQKNH-------IFRLTQGLQEALDRADLLKTERSDLEY 1196
Query: 441 ELERTIHSYQGQIISHEK 458
+LE Y SHEK
Sbjct: 1197 QLENIQVLY-----SHEK 1209
Score = 55.5 bits (132), Expect = 2e-07
Identities = 102/474 (21%), Positives = 189/474 (39%), Gaps = 104/474 (21%)
Query: 108 VESSLKDASFEKE----ATEAQSLEATCEK-------LNRSNSELEDEILCLEKELKEEK 156
++S K +S EK+ + E Q + C K L+R SE+E + E ELK +
Sbjct: 438 LDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASE 497
Query: 157 SKHS--EQD--------------------ELMADISKRIQSLED---------ESKSLKS 185
++ S EQD E+ + K +Q L D E K +
Sbjct: 498 TQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEY 557
Query: 186 QVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQES--------------QKQLLQEAEV 231
Q +M + Q+ E+ + + L E S+L+ES Q +LL+ +
Sbjct: 558 QAQVEEMRLMMNQLEEDLVSARRRSDLYE-SELRESRLAAEEFKRKATECQHKLLKAKDQ 616
Query: 232 WKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNL 291
K +V E K + K++AEQ L I+ L E+L K + E + +
Sbjct: 617 GKPEVGEYAKLE------KINAEQQLK-----IQELQEKLEKAVKASTEATELLQNIRQA 665
Query: 292 ELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE-- 349
+ E E ++ +G KKL+ A +L + + + + L + ++ EE
Sbjct: 666 KERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKI 725
Query: 350 --LTEHIKNLQTEQASLQSENTHFENE------------------NQKLQQKLKVMTELY 389
L IK ++ +L++ E E + K++ + + EL
Sbjct: 726 KVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS 785
Query: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
+ N++ + L + N + + EE +S++ ++ + + + + LEE+LE+
Sbjct: 786 EANKLAANSSLFTQRNMKAQ-EEMISELRQQKFYLETQAGKLEAQNRKLEEQLEK----- 839
Query: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTE--TELKFELLEKD 501
ISH+ + N L E L ++ E+ + +L TEL+ L E++
Sbjct: 840 ----ISHQDHSDKNRLL--ELETRLREVSLEHEEQKLELKRQLTELQLSLQERE 887
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 79.0 bits (193), Expect = 2e-14
Identities = 89/445 (20%), Positives = 193/445 (43%), Gaps = 46/445 (10%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 146
EE+ + ++ ++++KE E + E + ++E + + LE + R E + + L
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 147 CLEKEL--KEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 204
E++L K+E+ + +Q+E +R Q E + L+ + E + + EER
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 205 KIAIKDALNENSQLQE--SQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKES 262
+ ++ E + Q+ ++QL +E ++ +EQ +L +++ + ++ EQ L ++
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQ--QLRREQQLRREQQLRREQQLRREQQ 418
Query: 263 HIKTLTERLLKMKDWAAMLGEDITDDDNLELE-------MNSESENGAYLDNPPKGALKK 315
+ R + ++ E + L+ E + E E + K LK+
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 316 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENEN 375
E ER + +++L E ++ +E+ + L+ EQ + + + E
Sbjct: 479 ------------DQEEERRERWLKLEEEER-REQQERREQQLRREQEERREQRLKRQEEE 525
Query: 376 QKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL-----ET 430
++LQQ+L+ +L +E E + + L EE RLE+E + ++ + ++L E
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 431 YRKRAK-DLEEELERTIHSYQGQIISHEKKAHDN--------------WLAARNAERNLN 475
++R K + EE LE+ + + + + E++ + ER
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 476 DLRKENAHNRQKLTETELKFELLEK 500
LR+E R++ + E + E LE+
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQ 670
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/402 (18%), Positives = 169/402 (42%), Gaps = 39/402 (9%)
Query: 118 EKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKH-SEQDELMADISKRIQSL 176
E+E E + E+L + + + DE L +++ +E+ + +E+++L + +
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 177 EDESKSLKSQVAEAK-------------MTFKIFQMNEERLKIAIKDAL-NENSQLQESQ 222
DE + + ++ E + ++FQ EE+ + L E +LQE +
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 223 KQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLG 282
Q +E + +EQ+ +L +Q++ E + +Q +E ++ E
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE------------ 312
Query: 283 EDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE 342
+ + E + E + + L++ + + E ER + ++ +
Sbjct: 313 ----ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 343 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 402
++ +E+ + L+ EQ L+ E + + +Q+L+ +L +E +++ ++L
Sbjct: 369 EEERREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 403 E-ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQII--SHEKK 459
E E R E++ + + ++++ EE + KR EEE ER + Q + E++
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKR----EEETERHEQERRKQQLKRDQEEE 483
Query: 460 AHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
+ WL ER R+E R++ E + + E++
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Score = 63.9 bits (154), Expect = 5e-10
Identities = 77/401 (19%), Positives = 170/401 (42%), Gaps = 47/401 (11%)
Query: 94 EKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELK 153
E+ L+++E E ++ + E+E + + E+ R E LE++ +
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE-------LERQYR 1081
Query: 154 EEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALN 213
+E+ E+++L+ + ++ + E E + + + + + + + E+R + ++
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 214 ENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLK 273
E ++Q+ ++QLL+E E K + EL +Q E+ + EQ+L +++ + ER +
Sbjct: 1142 EEEEVQQEEEQLLRE-EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 274 MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNA---SLKTLE 330
++ E+ + Y D + LK K NA + +
Sbjct: 1201 EEE-----------------ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 331 GERNQIYIQLSEV---DKTKEELTEHI------KNLQTEQASLQSENTHFENENQ--KLQ 379
G N+ + QL + D+ ++ +H+ ++ + E+ Q + HF E Q + +
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE 1303
Query: 380 QKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE 439
QK + + E +L R+ E+ R E + K + ++ + E + R++ +D +
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE--QPLRRQERDRK 1361
Query: 440 EELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKE 480
E H QG+ E++ R ER L++E
Sbjct: 1362 FREEELRHQEQGRKFLEEEQ------RLRRQERERKFLKEE 1396
Score = 56.6 bits (135), Expect = 8e-08
Identities = 97/471 (20%), Positives = 183/471 (38%), Gaps = 50/471 (10%)
Query: 113 KDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKR 172
K A E+ E Q L+ E+L R E E++ +EE+ E+++L+ + ++
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQE-QERQYREEEQLQQEEEQLLREEREK 950
Query: 173 IQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVW 232
+ E E + K + + K + + E+R + + E +LQ+ ++QLL+E E
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE-ERE 1009
Query: 233 KEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE 292
K + E +Q ++ + EQ+L + E + L ER + + + E
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLRE-EREKRRLQERERQYR-------------EEEE 1055
Query: 293 LEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTE 352
L+ E G + + L++ E E Q QL + K E
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRK----------EEELQQEEEQLLREEPEKRRRQE 1105
Query: 353 HIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEE 412
+ + E+ Q E E +K +++ +L R+ EE + E+E+
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQ-------------ELERQYREEEEVQQEEEQ 1152
Query: 413 KLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAER 472
L + EK +ELE + ++L++E E+ + Q EK+ + R E
Sbjct: 1153 LLREEPEK--RRRQELERQYREEEELQQEEEQLLREEQ------EKRRQERERQYREEEE 1204
Query: 473 NLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPLDHQITNERG 532
RK+ + + ++ + ++E EK+ D GR + D Q+ + +
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWE-PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Query: 533 ESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDR 583
+ L + D W Q R FP Q + +R+DR
Sbjct: 1264 QQDLQHLLG-EQQERDREQERRRW-QQRDRHFPEEEQLEREEQKEAKRRDR 1312
Score = 54.7 bits (130), Expect = 3e-07
Identities = 89/422 (21%), Positives = 175/422 (41%), Gaps = 50/422 (11%)
Query: 100 QKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELK-EEKSK 158
++E + E E L+ K E Q L+ E+ E + + L E++L+ +E+ +
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQER-EEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Query: 159 HSEQDELMADISKRIQSLEDESKSLKSQ----VAEAKMTFKIFQMNEERLKIAIKDALNE 214
+ EL + +R + LE+E + + Q + + + + ++R + + E
Sbjct: 1502 KFREQELRSQEPER-KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 215 NSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSK---VHAEQVLNDKESHIKTLTERL 271
QE ++Q L E +++ L +QKV ++ + + EQ L +E + ER
Sbjct: 1561 EQLRQEREEQQLSRQE--RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 272 LKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK---- 327
K ++ +L E E +++ + + +L+ P+ ++ + + K
Sbjct: 1619 RKFREDEQLLQE------REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 328 ---TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKV 384
EGE Q+ Q E D+ E + ++ + E+ LQ E + Q+L++K +
Sbjct: 1673 EQLLQEGEEQQLRRQ--ERDRKFREEEQQLRRQERERKFLQEEQ---QLRRQELERKFRE 1727
Query: 385 MTELYQENEMKL------HRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDL 438
+L QE E + +RK+ EE R E+EE+ + E+ EE + L
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE--------EQL 1779
Query: 439 EEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELL 498
+E E + Q+ S E ER LR + + + E +L+ E
Sbjct: 1780 RQERE------EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
Query: 499 EK 500
E+
Sbjct: 1834 EQ 1835
Score = 51.6 bits (122), Expect = 3e-06
Identities = 79/442 (17%), Positives = 180/442 (40%), Gaps = 57/442 (12%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEIL 146
EE+ +L ++ ++ E + + ++ ++E + E ++L R E D++L
Sbjct: 523 EEEERLQQR---LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 147 CLEKELKEEKSKHSEQDELMADISKR-IQSLEDESKSLKSQVAEAKMTFKIFQMNEERLK 205
E+E ++++ K +++ L + + ++ LE E + + K + EER +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERR--------EQRLKREEPEEERRQ 631
Query: 206 IAIKDALNENSQLQE--SQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESH 263
+K E + Q+ ++Q +E + +E+ E +Q++ E + EQ L ++E
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ- 690
Query: 264 IKTLTERLL-KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPK--GALKKLIHAA 320
+ ER+ ++ W +LE +++ P K G ++
Sbjct: 691 -EQARERIKSRIPKW------------QWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 321 KLNASLKTLEG-ERNQIYIQLSEVDKTK--------EELTEHIKNLQTEQASLQSENTHF 371
K L+ E + + Q E ++ + EE +E + + + L+ +
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
Query: 372 ENENQKLQQKLKVMTELYQENEMKLHRKLT------VEENYRLEKEEKLSKVDEKISHAT 425
++ Q++ + + E ++ + + R+ +EE +L++ E+ ++ E+
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 426 EELETYRKRAK--------DLEEELERTIHSYQGQIISHEKKAHDNWLAARNAE---RNL 474
E+ E R + + LEEE +R H+ + E+ + L E R
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 475 NDLRKENAHNRQKLTETELKFE 496
+ R+ RQ E +L+ E
Sbjct: 918 REKRRRQEQERQYREEEQLQQE 939
Score = 50.8 bits (120), Expect = 5e-06
Identities = 69/373 (18%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 132 EKLNRSNSELEDEILCLEKELKEEKSKHSEQ---DELMADISKRIQSLEDESKSLKSQVA 188
++L R ++ L E+E + + KH ++ L + +R L+ E ++ + +
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Query: 189 EAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFED 248
K K Q E R + + Q + ++QL +E E +EQ + +++ +
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 249 SKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNP 308
+Q+ ++E E+LLK ++ + E + L+ E + +
Sbjct: 531 RLRSEQQLRREQEER----REQLLKREEEKRL--EQERREQRLKREQEERRDQLLKREEE 584
Query: 309 PKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSEN 368
+ K +L LK E ER L + ++ ++ L + Q L+SE
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVER------LEQEERREQRLKREEPEEERRQQLLKSE- 637
Query: 369 THFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL 428
E E ++ QQ + E ++ + + +E+ + E EE+ + + +
Sbjct: 638 ---EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 429 ETYRKRAKDLEEELERTIHSYQGQIISH------EKKAHDNWLAARNAERNLNDLRKENA 482
E + R + +LE + Q ++ S +++ + R E L +E A
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 483 HNRQKLTETELKF 495
H +Q+ E F
Sbjct: 755 HRQQQEEEQRRDF 767
Score = 48.5 bits (114), Expect = 2e-05
Identities = 95/461 (20%), Positives = 181/461 (39%), Gaps = 63/461 (13%)
Query: 87 EEKSKLLEKFSLVQKEYEG---YEVESSLKDASFEKEATEAQSLEATCEKLNRSNSEL-- 141
EE+ E+ L+++E E E+E ++ E + E Q L EK R E
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEE-EVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 142 -EDEILCLEKE--LKEEKSK--------HSEQDELMADISKRIQSLEDESKSLKSQVAEA 190
E+E L E+E L+EE+ K + E++EL K+ ED+ LK Q
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 191 KMTF----KIFQMNEERLKIA-IKDALNENSQLQESQKQLL---------QEAEVWK--- 233
K K++ E + ++D+ + Q Q+ + LL QE W+
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
Query: 234 ------EQVSELNKQKVTFEDSKVHAE-QVLNDKESHIKTLTERLLKMKDWAAMLGE--- 283
EQ+ +++ D K E Q+L ++ + E K ++ +L E
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 284 -----DITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 338
D E E+ + + +L+ + L++ K + L + + +
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQR--LRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 339 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKL-- 396
+ K +EE +Q S Q + F E Q+++++ + L +E +++
Sbjct: 1409 RQDRDRKFREE---------EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 397 HRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE-EELERTIHSYQGQIIS 455
HRK EE E+EE+ E+ EE + R++ +D + E E + + +
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 456 HEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFE 496
E++ H + + R+E R++ + + + E
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Score = 40.8 bits (94), Expect = 0.005
Identities = 72/390 (18%), Positives = 156/390 (40%), Gaps = 12/390 (3%)
Query: 67 RSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS 126
+ RL +E++L L E+ + E+ K E E S E+E Q
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 127 LEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMAD----ISKRIQSLEDESKS 182
L ++ + E+E LE+ LK E + + EL + +RI+S + +
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 183 LKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQ 242
A+A+ + K++ ++ + E + +ES+ Q +E ++Q E ++
Sbjct: 707 QLESEADARQS-KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Query: 243 KVTF----EDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
T+ E+ Q L+ + ++ ER L+ ++ + +++ E
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPP-LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
Query: 299 SENGAYLDN-PPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD-KTKEELTEHIKN 356
E L + L++ A +L L+ ++ + Q D K + +L E K
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 357 LQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
+ + + E Q LQ++ + + +E + ++ E +L++EE+
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTI 446
+E+ +E E ++ K L+++ E+ +
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLL 974
Score = 39.3 bits (90), Expect = 0.014
Identities = 70/338 (20%), Positives = 142/338 (42%), Gaps = 47/338 (13%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLKDASF-EKEATEAQSLEATCEKLNRSNSELEDEI 145
E++ K +E ++++ EG + +D F E E + E + R LE+E
Sbjct: 1592 EQERKFMEDEQQLRRQ-EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 146 LCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLK 205
L ++ +E++ +H ++D + + +Q E E + L+ Q + K F+ E++L+
Sbjct: 1651 Q-LRRQEREQQLRH-DRDRKFREEEQLLQ--EGEEQQLRRQERDRK-----FREEEQQLR 1701
Query: 206 IAIKDA--LNENSQL--QESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKE 261
++ L E QL QE +++ +E ++ +E E +++ + + EQ+ ++E
Sbjct: 1702 RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI-LEEEQLRPERE 1760
Query: 262 SHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAK 321
ER K ++ E+ + E ++ S+ + + +
Sbjct: 1761 EQQLRRQERDRKFRE------EEQLRQEREEQQLRSQESDRKFREE-------------- 1800
Query: 322 LNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQK 381
+ L ER + ++ + D E ++ + EQ Q + + E Q Q+
Sbjct: 1801 -----EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 382 L--KVMTELYQENEMKLH----RKLTVEENYRLEKEEK 413
+ EL+QE E K RKL E R +KEE+
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 78.6 bits (192), Expect = 2e-14
Identities = 97/488 (19%), Positives = 206/488 (42%), Gaps = 88/488 (18%)
Query: 95 KFSLVQKEYEGYEVESSLK--DASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKEL 152
K L ++ +E+E + D+ + EAQ + EKL R L E L+++L
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502
Query: 153 KEE---------------------KSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 191
+E+ S+ S+ + +A + K+++ LE + K + ++ E
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
Query: 192 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
T ++ + + RL++ ++ +S+ ES+ + ++EA + +L + +V E+
Sbjct: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR--QSCQKKLKQMEVQLEEEYE 1620
Query: 252 HAEQVLNDK---ESHIKTLTERLLK------------MKDWAAMLGEDITDDDNLELEMN 296
++VL +K E + TL++++ + +K A+L + D+L+
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
Query: 297 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 356
S+ E A L N + + A K + K +E E +++Q+ ++ K K L E +
Sbjct: 1681 SKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Query: 357 LQTE---------------------------QAS--------LQSENTHFENENQKLQQK 381
LQ E QAS LQ++ E Q+LQ+K
Sbjct: 1737 LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEK 1796
Query: 382 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 441
L+ + +++++ + V+++ +E K+ +++ ++ +++ A L+E
Sbjct: 1797 LQAL-----QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKEN 1851
Query: 442 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
+E+ +I + ++ N + +R L D ++E +K E K LE D
Sbjct: 1852 MEKLTEERDQRIAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD 1907
Query: 502 PYALDVPN 509
+L+ N
Sbjct: 1908 LESLEAAN 1915
Score = 56.2 bits (134), Expect = 1e-07
Identities = 94/467 (20%), Positives = 193/467 (41%), Gaps = 54/467 (11%)
Query: 60 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK 119
W+ F +VR + V ++ + EE +L K +KE + S ++ +
Sbjct: 1237 WKLFTTVRPLIEVQLSEE---QIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISE 1293
Query: 120 EATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
+E T E ++ E L EKE+KE ++++ +L+ +
Sbjct: 1294 LTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQY--------------DALKKQ 1339
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 239
+ ++ +V EA++ + ++N E D + + + ++ ++E + K+++ +
Sbjct: 1340 MEVMEMEVMEARL-IRAAEINGE------VDDDDAGGEWRLKYERAVREVDFTKKRLQQE 1392
Query: 240 NKQKVTFE-DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELE---- 294
+ K+ E +K E+ L D ++ + L ++K L ++ D L LE
Sbjct: 1393 FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAEL-QDTKLHLEGQQV 1451
Query: 295 MNSESEN-----GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE 349
N E E + L + A ++ + KL L E + QL E D
Sbjct: 1452 RNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAG 1511
Query: 350 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR-----KLTVEE 404
T+ + +L+ E + S+ + E K++++L+ + ++ E +L ++ +
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571
Query: 405 NYRLEKE-EKLSKVDEK-ISHATEELETYR----KRAKDLEEELERTIHSYQGQIISHEK 458
RLE E E++ + K + EE+E R K+ K +E +LE Q + EK
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQK--VLREK 1629
Query: 459 KAHDNWLAARNAERNLND------LRKENAHNRQKLTETELKFELLE 499
+ + LA + + N D LRK+ + L + +L + L+
Sbjct: 1630 RELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK 1676
Score = 55.1 bits (131), Expect = 2e-07
Identities = 78/387 (20%), Positives = 158/387 (40%), Gaps = 45/387 (11%)
Query: 76 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 135
K++ + L E+K K+L E E+E L S + + +S + + L
Sbjct: 1609 KQMEVQLEEEYEDKQKVLR---------EKRELEGKLATLSDQVNRRDFESEKRLRKDLK 1659
Query: 136 RSNSELEDEILCLE---------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQ 186
R+ + L D L L+ +E+ + K++ E + A K +++E E + L Q
Sbjct: 1660 RTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ 1719
Query: 187 V---AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQK 243
+ A+AK EE+L ++ ++L+E Q+ + + + K V++ ++
Sbjct: 1720 IDDIAKAKTAL------EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 244 VTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNL--------ELEM 295
D + E+ +K+ L E+L ++ L + + D + ELE
Sbjct: 1774 AQINDLQAQLEEANKEKQE----LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1829
Query: 296 NSESENGAY-----LDNPPKGALKKLIHAAKLNASLKTLEGERNQ-IYIQLSEVDKTKEE 349
E E L + K ++KL + + E E+N+ + QL + + E
Sbjct: 1830 RLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
Query: 350 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 409
L ++ L+ + E NQ LQ LK+ + + + + ++ +EN L
Sbjct: 1890 LARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLI 1949
Query: 410 KEEKLSKVDEKISHATEELETYRKRAK 436
E S VD ++ + ++++ + K
Sbjct: 1950 NSEGDSDVDSELEDRVDGVKSWLSKNK 1976
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 78.6 bits (192), Expect = 2e-14
Identities = 97/488 (19%), Positives = 206/488 (42%), Gaps = 88/488 (18%)
Query: 95 KFSLVQKEYEGYEVESSLK--DASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKEL 152
K L ++ +E+E + D+ + EAQ + EKL R L E L+++L
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502
Query: 153 KEE---------------------KSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAK 191
+E+ S+ S+ + +A + K+++ LE + K + ++ E
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
Query: 192 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
T ++ + + RL++ ++ +S+ ES+ + ++EA + +L + +V E+
Sbjct: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR--QSCQKKLKQMEVQLEEEYE 1620
Query: 252 HAEQVLNDK---ESHIKTLTERLLK------------MKDWAAMLGEDITDDDNLELEMN 296
++VL +K E + TL++++ + +K A+L + D+L+
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
Query: 297 SESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 356
S+ E A L N + + A K + K +E E +++Q+ ++ K K L E +
Sbjct: 1681 SKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Query: 357 LQTE---------------------------QAS--------LQSENTHFENENQKLQQK 381
LQ E QAS LQ++ E Q+LQ+K
Sbjct: 1737 LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEK 1796
Query: 382 LKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEE 441
L+ + +++++ + V+++ +E K+ +++ ++ +++ A L+E
Sbjct: 1797 LQAL-----QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKEN 1851
Query: 442 LERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
+E+ +I + ++ N + +R L D ++E +K E K LE D
Sbjct: 1852 MEKLTEERDQRIAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD 1907
Query: 502 PYALDVPN 509
+L+ N
Sbjct: 1908 LESLEAAN 1915
Score = 56.2 bits (134), Expect = 1e-07
Identities = 94/467 (20%), Positives = 193/467 (41%), Gaps = 54/467 (11%)
Query: 60 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEK 119
W+ F +VR + V ++ + EE +L K +KE + S ++ +
Sbjct: 1237 WKLFTTVRPLIEVQLSEE---QIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISE 1293
Query: 120 EATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
+E T E ++ E L EKE+KE ++++ +L+ +
Sbjct: 1294 LTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQY--------------DALKKQ 1339
Query: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 239
+ ++ +V EA++ + ++N E D + + + ++ ++E + K+++ +
Sbjct: 1340 MEVMEMEVMEARL-IRAAEINGE------VDDDDAGGEWRLKYERAVREVDFTKKRLQQE 1392
Query: 240 NKQKVTFE-DSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELE---- 294
+ K+ E +K E+ L D ++ + L ++K L ++ D L LE
Sbjct: 1393 FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAEL-QDTKLHLEGQQV 1451
Query: 295 MNSESEN-----GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE 349
N E E + L + A ++ + KL L E + QL E D
Sbjct: 1452 RNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAG 1511
Query: 350 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR-----KLTVEE 404
T+ + +L+ E + S+ + E K++++L+ + ++ E +L ++ +
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571
Query: 405 NYRLEKE-EKLSKVDEK-ISHATEELETYR----KRAKDLEEELERTIHSYQGQIISHEK 458
RLE E E++ + K + EE+E R K+ K +E +LE Q + EK
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQK--VLREK 1629
Query: 459 KAHDNWLAARNAERNLND------LRKENAHNRQKLTETELKFELLE 499
+ + LA + + N D LRK+ + L + +L + L+
Sbjct: 1630 RELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK 1676
Score = 50.1 bits (118), Expect = 8e-06
Identities = 78/390 (20%), Positives = 156/390 (40%), Gaps = 57/390 (14%)
Query: 76 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 135
K++ + L E+K K+L E E+E L S + + +S + + L
Sbjct: 1609 KQMEVQLEEEYEDKQKVLR---------EKRELEGKLATLSDQVNRRDFESEKRLRKDLK 1659
Query: 136 RSNSELEDEILCLE---------KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQ 186
R+ + L D L L+ +E+ + K++ E + A K +++E E + L Q
Sbjct: 1660 RTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ 1719
Query: 187 V---AEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQK 243
+ A+AK EE+L ++ ++L+E Q+ + + + K V++ ++
Sbjct: 1720 IDDIAKAKTAL------EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 244 VTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNL--------ELEM 295
D + E+ +K+ L E+L ++ L + + D + ELE
Sbjct: 1774 AQINDLQAQLEEANKEKQE----LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1829
Query: 296 NSESENGAY-----LDNPPKGALKKLIHAAKLNASLKTLEGERNQ-IYIQLSEVDKTKEE 349
E E L + K ++KL + + E E+N+ + QL + + E
Sbjct: 1830 RLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
Query: 350 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLE 409
L ++ L+ + E NQ LQ LK+ + + + + ++ +EN
Sbjct: 1890 LARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDEN---- 1945
Query: 410 KEEKLSKVDEKISHATEELETYRKRAKDLE 439
++ I+ + + Y+KR LE
Sbjct: 1946 --------EDLINSLQDMVTKYQKRKNKLE 1967
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 78.2 bits (191), Expect = 3e-14
Identities = 104/506 (20%), Positives = 213/506 (42%), Gaps = 104/506 (20%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEV-ESSLKDASFEKEATEAQSLEATCEK 133
+ L +L + ++ K+ +L+QK E + E +D + +A E ++ A +
Sbjct: 508 QNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGET--AVLNQ 565
Query: 134 LNRSNSELEDEILCLEKELKEEKSKHSEQDELMAD-----------ISKRIQSLEDESKS 182
L N L++++ L ++LK + H + E + D R+ SLE
Sbjct: 566 LQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNE 625
Query: 183 LKSQVAEAKMTFKIFQMN---EERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 239
L SQ+ E+K K+ Q++ + + ++ + + +Q + Q L +++ EL
Sbjct: 626 LNSQLNESKE--KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQEL 683
Query: 240 NK-----QKVT--FEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDIT--DDDN 290
NK +VT +D + H Q+ ESH+K E+ L ++ L I + D+
Sbjct: 684 NKITTQLDQVTAKLQDKQEHCSQL----ESHLKEYKEKYLSLEQKTEELEGQIKKLEADS 739
Query: 291 LELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERN-QIYIQLSEVDKTKEE 349
LE++ + E AL+ L +LN L+ E + Q+ ++ V T+ +
Sbjct: 740 LEVKASKEQ------------ALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLD 787
Query: 350 LTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE----LYQENEMKLHRKLTVEEN 405
L + + L+ S++ + T E E Q L+Q + +++ ++E ++ +T +
Sbjct: 788 LQKKSEALE----SIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQK 843
Query: 406 YRLEKE----------EKLSKVDEKISHATEELETYRKRAKDLEEELERT---------- 445
++EKE +KLSKV + + ++ E E ++ K +LE+T
Sbjct: 844 VKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQV 903
Query: 446 -----------------------------IHSYQGQIISHEKKAHDNWLAARNAERNLND 476
++S Q Q+I + N + + N+N+
Sbjct: 904 QMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINE 963
Query: 477 LRKENAHNRQKL--TETELKFELLEK 500
L++ + ++++ + ELK +L+K
Sbjct: 964 LKQSSEQKKKQIEALQGELKIAVLQK 989
Score = 77.8 bits (190), Expect = 3e-14
Identities = 89/449 (19%), Positives = 193/449 (42%), Gaps = 44/449 (9%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSE--LEDE 144
EE K LEK+ +Q++ + + + D+S E ++ E Q EA E N + E +
Sbjct: 107 EELKKELEKYQGLQQQEA--KPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQK 164
Query: 145 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 204
L E+ + KSK+ E+ L +++ L +E + + + K T + + E +
Sbjct: 165 AAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLK-TELLQRPGIEDV 223
Query: 205 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 264
+ K+ + + + + +E+E K++ +L Q + E + L +
Sbjct: 224 AVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEV 283
Query: 265 KTLTERLLKMKDWAAML---GEDITDD------DNLELEMNSESENGAYLDNPPKGALKK 315
+ L K+K L + +T++ D +LE +E N +K
Sbjct: 284 AVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLE-EKHNEESVSKKNIQATLHQK 342
Query: 316 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENEN 375
+ +L + L E ++I+++LSE + ++L E + ++T+ L++E + +
Sbjct: 343 DLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQR 402
Query: 376 QKLQQK-LKVMTELYQ---------------ENEMKLHRKLTVEENYRLEKEEKLSKVDE 419
++ +Q L++ +E+ Q +K R+L+ E+ ++KE++++ +
Sbjct: 403 EEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEK--LMDKEQQVADLQL 460
Query: 420 KISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRK 479
K+S E+L+ + +L+ +L++T +Q Q + R A+ +L + +
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQ----QALQQSTTAKLREAQNDLEQVLR 516
Query: 480 ENAHNRQKLTETEL-------KFELLEKD 501
+ QK+ E LLEK+
Sbjct: 517 QIGDKDQKIQNLEALLQKSKENISLLEKE 545
Score = 74.3 bits (181), Expect = 4e-13
Identities = 90/435 (20%), Positives = 180/435 (41%), Gaps = 44/435 (10%)
Query: 87 EEKSKLLEKFSLVQKEYEGYEVESSLK--DASFEKEATEAQSLEATCEKLNRSNSELEDE 144
E SK + +L QK+ + +++S L + S + E +KL SE+E +
Sbjct: 328 ESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETK 387
Query: 145 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 204
L+ E K+ + + E+++ + I L + + Q+ EA K E+
Sbjct: 388 YQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLK------EQR 441
Query: 205 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 264
+++ + +++ Q+ + Q +L + E KE+V+ + + + +K ++ ++S
Sbjct: 442 QLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTT 501
Query: 265 KTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNA 324
L E ++ +G+ NLE + EN + L+ L A
Sbjct: 502 AKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEK----------EREDLYA 551
Query: 325 SLKTLEGERNQIYIQLSEVDKTKEE----LTEHIKNLQTEQASLQSENTHFENENQKLQQ 380
++ EGE + QL E + T +E LTE +KN Q+E EN H + + QK
Sbjct: 552 KIQAGEGE-TAVLNQLQEKNHTLQEQVTQLTEKLKN-QSESHKQAQENLHDQVQEQKAHL 609
Query: 381 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATE-------------- 426
+ Q+ + L + + E +EK+S++D +I TE
Sbjct: 610 RAA------QDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA 663
Query: 427 ELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQ 486
+L+ + A++ ++ ++ ++ Q+ K D E +L + +++ Q
Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723
Query: 487 KLTETELKFELLEKD 501
K E E + + LE D
Sbjct: 724 KTEELEGQIKKLEAD 738
Score = 71.2 bits (173), Expect = 3e-12
Identities = 91/447 (20%), Positives = 183/447 (40%), Gaps = 67/447 (14%)
Query: 88 EKSKLLEKFSLVQKEYEGYEVESSLKDAS--FEKEATEAQS----LEATCEKLNRSNSEL 141
EK L+ + S V+ + +V SLK++ FEKE + ++ LE TC++L
Sbjct: 847 EKEALMTELSTVKDKLS--KVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ 904
Query: 142 EDEILCLEKELKEEKSKHSE-----------QDELMADISKRIQSLEDESKSLKSQVAEA 190
+ L +KELK+ K E E + ++ E E + L+ + E
Sbjct: 905 MENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINEL 964
Query: 191 KMTF----KIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTF 246
K + K + + LKIA+ ++LQ+ Q QE KE++S L +
Sbjct: 965 KQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN---Y 1021
Query: 247 EDSKVHAEQVLND---KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGA 303
E S+ +Q+ +D +ES + + L +++ ++ ED+ + N
Sbjct: 1022 EKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRN------------- 1068
Query: 304 YLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQ-----LSEVDKTKEELTEHIKNLQ 358
G KLI K + + + + +Q L ++ K K + + N +
Sbjct: 1069 -----QIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK 1123
Query: 359 TEQASLQSENTHFENENQKLQQKLKV--MTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
++ A ++ E E KL ++LK + + + +K ++L +++ +LE + K
Sbjct: 1124 SKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQ--KLELQGKADS 1181
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIIS-----------HEKKAHDNWL 465
+ + + + + K EEEL++ + ++ S HE+ +
Sbjct: 1182 LKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTM 1241
Query: 466 AARNAERNLNDLRKENAHNRQKLTETE 492
NL ++KE ++++++E E
Sbjct: 1242 QITALNENLGTVKKEWQSSQRRVSELE 1268
Score = 69.3 bits (168), Expect = 1e-11
Identities = 94/463 (20%), Positives = 198/463 (42%), Gaps = 76/463 (16%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 134
E++L L E++ EK +++ +++ S + +++ T + L+ +K
Sbjct: 427 ERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKT 486
Query: 135 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 194
+ + E + +L+E ++ + + D ++IQ+LE + + ++K
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLE-------ALLQKSKENI 539
Query: 195 KIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAE 254
+ + E L I+ E + L QL ++ +EQV++L ++ +S A+
Sbjct: 540 SLLEKEREDLYAKIQAGEGETAVL----NQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQ 595
Query: 255 QVLND----KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPK 310
+ L+D +++H++ +R+L ++ T + L ++N E + LD K
Sbjct: 596 ENLHDQVQEQKAHLRAAQDRVLSLE----------TSVNELNSQLNESKEKVSQLDIQIK 645
Query: 311 GALKKLIHA--------AKLNASLKTLEG-------ERNQIYIQLSEV-----DKTK--E 348
+ L+ A A L L T + E N+I QL +V DK +
Sbjct: 646 AKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCS 705
Query: 349 ELTEHIKNLQTEQASLQSENTHFENENQKLQ--------QKLKVMTELYQENEMKLHRKL 400
+L H+K + + SL+ + E + +KL+ K + + +L Q+ ++ +L
Sbjct: 706 QLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLEL 765
Query: 401 TVEE-NYRLEKEEKL-SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 458
E + +LE E+++ S + +E LE+ +++ EE E+ I + +S E
Sbjct: 766 RATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEE--EKQILKQDFETLSQET 823
Query: 459 KAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
K ++ E +NR + T TEL+ +EK+
Sbjct: 824 K-----------------IQHEELNNRIQTTVTELQKVKMEKE 849
Score = 65.1 bits (157), Expect = 2e-10
Identities = 97/437 (22%), Positives = 175/437 (40%), Gaps = 55/437 (12%)
Query: 74 REKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEK 133
+++ + + S L E K K L SL QK E L+ S E +A++ Q+L+ ++
Sbjct: 700 KQEHCSQLESHLKEYKEKYL---SLEQKTEELEGQIKKLEADSLEVKASKEQALQ-DLQQ 755
Query: 134 LNRSNSELEDEILCLEKELKEEKSKHS-------EQDELMADISKRIQSLEDESKSLKSQ 186
+ N++LE L K+L+ EK S ++ E + I +++ E+E + LK
Sbjct: 756 QRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQD 815
Query: 187 VAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSE----LNKQ 242
KI E L I+ + E +++ ++ L+ E K+++S+ L
Sbjct: 816 FETLSQETKI---QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNS 872
Query: 243 KVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENG 302
K FE + + D E K L +L + + + L+ + E E
Sbjct: 873 KSEFEKENQKGKAAILDLEKTCKELKHQL------QVQMENTLKEQKELKKSLEKEKEAS 926
Query: 303 AYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA 362
L ++LI A +LK E E Q+ ++E+ ++ E+ + I+ LQ E
Sbjct: 927 HQLKLELNSMQEQLIQAQN---TLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELK 983
Query: 363 SLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIS 422
+ T EN KL ++LT ++EK+S +
Sbjct: 984 IAVLQKTELEN---------------------KLQQQLTQAAQELAAEKEKISVLQNNYE 1022
Query: 423 HATEELETYRKRAKDLEEELERTIHSYQGQIISHEKK---AHDNWLAARNAERNLNDLRK 479
+ E + + E EL T + + S E+K A ++ ++ RN N N L +
Sbjct: 1023 KSQETFKQLQSDFYGRESELLAT----RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQ 1078
Query: 480 ENAHNRQKLTETELKFE 496
E + L + K E
Sbjct: 1079 ELKTAKATLEQDSAKKE 1095
Score = 62.4 bits (150), Expect = 2e-09
Identities = 75/309 (24%), Positives = 145/309 (46%), Gaps = 23/309 (7%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 134
E+KL+L LI ++++ + L+Q E +++L+ S +KE Q L+ C+ L
Sbjct: 1053 EEKLSLAQEDLISNRNQIGNQNKLIQ---ELKTAKATLEQDSAKKE----QQLQERCKAL 1105
Query: 135 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 194
+++ E EKEL EKSK +E +E+ K I L +E KS K + +
Sbjct: 1106 Q----DIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNL 1161
Query: 195 KIFQ--MNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVH 252
K + + +++L++ K + + QE + Q + + +V KE+ EL K+ + +++K+H
Sbjct: 1162 KDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE-EELKKEFIE-KEAKLH 1219
Query: 253 AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGA 312
+E + +KE +K E K+ L E++ ++ E S + L+
Sbjct: 1220 SE--IKEKEVGMKKHEENEAKLTMQITALNENL---GTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 313 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE 372
++ A L A+++ + ER + + + + E+L + LQ + + +
Sbjct: 1275 RGEI---AVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELG 1331
Query: 373 NENQKLQQK 381
ENQ LQ K
Sbjct: 1332 RENQSLQIK 1340
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 78.2 bits (191), Expect = 3e-14
Identities = 97/450 (21%), Positives = 198/450 (44%), Gaps = 56/450 (12%)
Query: 82 LSGLIEEKSKLLEKFSLVQKE--YEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNS 139
L+ I E K + + V+K+ +E E+++SL++A E E + L E LN+ S
Sbjct: 1516 LTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLE-LNQVKS 1574
Query: 140 ELEDEILCLEKELKEEKSKH-----SEQDELMADISKR-------------IQSLEDESK 181
E++ +I ++EL + K H S Q L A+I R + +E +
Sbjct: 1575 EIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLN 1634
Query: 182 SLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNK 241
Q AEA + Q + ++ + DA+ L+E + + A + + +V EL
Sbjct: 1635 HANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRA 1694
Query: 242 QKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESEN 301
E + AEQ L D ++ L + + + L DI+ ++ E+ N
Sbjct: 1695 SLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARN 1754
Query: 302 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ--- 358
+ A K + AA + LK + + +++ K+ + + +K+LQ
Sbjct: 1755 AE------EKAKKAITDAAMMAEELKKEQDTS-------AHLERMKKNMEQTVKDLQLRL 1801
Query: 359 --TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSK 416
EQ +L+ + + QKL+ +++ + E+E++ +K VE L K E+ K
Sbjct: 1802 DEAEQLALKGG----KKQIQKLEARVREL-----ESEVESEQKHNVEAVKGLRKHERRVK 1852
Query: 417 VDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
++++ TEE R +DL ++L+ + +Y+ Q E++++ N R + L +
Sbjct: 1853 ---ELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEE 1909
Query: 477 LRK-----ENAHNRQKLTETELKFELLEKD 501
++ E+ N+ ++ E+ +++ ++
Sbjct: 1910 AKERADIAESQVNKLRVKSREVHTKVISEE 1939
Score = 74.3 bits (181), Expect = 4e-13
Identities = 94/460 (20%), Positives = 188/460 (40%), Gaps = 43/460 (9%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEV----ESSLKDASFEKEATEAQSLEAT 130
EK++A M + K +L K +KE E V E + + EA E
Sbjct: 850 EKEMANMKEEFEKTKEELA-KTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 131 CEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 190
C++L ++ +LE +I KE + +++E+ A+++ + + LEDE LK + +
Sbjct: 909 CDQLIKTKIQLEAKI-------KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
Query: 191 KMTF------------KIFQMNEER--LKIAIKDALNENSQLQESQKQLLQEAEVWKEQV 236
++T K+ + EE L I E LQE+ +Q L + ++ +++V
Sbjct: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKV 1021
Query: 237 SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMN 296
+ L K K E E L ++ L K++ + E D +N + ++N
Sbjct: 1022 NTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLN 1081
Query: 297 SESENGAY--------LDNPPKGALKKLIHAAKLNASLKTLEGE-------RNQIYIQLS 341
+ + + +++ A++ +L A ++ LE E R + Q S
Sbjct: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 342 EVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLT 401
++ + EE++E ++ ++ N E E QK+++ L+ T ++ L +K
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHA 1201
Query: 402 VEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAH 461
E+ + L +V +K+ EL+ E + + +++ + E +
Sbjct: 1202 DSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLS 1261
Query: 462 DNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKD 501
+ +R +N+L + A R E +L EKD
Sbjct: 1262 EIKTKEEEQQRLINELSAQKA--RLHTESGEFSRQLDEKD 1299
Score = 65.1 bits (157), Expect = 2e-10
Identities = 86/421 (20%), Positives = 177/421 (42%), Gaps = 40/421 (9%)
Query: 75 EKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKL 134
EK + L E K+K E+ L+ E + + F ++ E +A +L
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLIN-ELSAQKARLHTESGEFSRQLDEK---DAMVSQL 1305
Query: 135 NRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTF 194
+R +I L+++L+EE S + L ++ + + Q A+A++
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYE--EEQEAKAELQR 1363
Query: 195 KIFQMNEERLKIAIK---DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
+ + N E + K DA+ +L+E++K+L Q + +E V +N + + E +K
Sbjct: 1364 GMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQ 1423
Query: 252 HAEQVLNDKESHIKTLTERLL----KMKDWAAMLGEDITDDDNLELEMNSESENGAYLDN 307
+ + D ++ + K +++ +L E + + E+ + + L
Sbjct: 1424 RLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLST 1483
Query: 308 PPKGALKKLIHAAKLNAS-LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQS 366
L K+ +A + + L+TL+ E + ++S++ + E +HI L+ + L
Sbjct: 1484 ----ELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQL-- 1537
Query: 367 ENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATE 426
++E +LQ L+ + E K+ R +LE + S++D KI+ E
Sbjct: 1538 -----DHEKSELQTSLEEAEASLEHEEGKILR-------IQLELNQVKSEIDRKIAEKDE 1585
Query: 427 ELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAH-NR 485
EL+ L+ R + S Q + + + +D + E +LN++ + H NR
Sbjct: 1586 ELD-------QLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANR 1638
Query: 486 Q 486
Q
Sbjct: 1639 Q 1639
Score = 65.1 bits (157), Expect = 2e-10
Identities = 86/430 (20%), Positives = 181/430 (42%), Gaps = 43/430 (10%)
Query: 85 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDE 144
L E K KL ++ ++ E + + + + ++ E + L E+ N + L+ +
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKK 1449
Query: 145 ILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL 204
+K L E K K+ E +++ + ES+SL +++ + K ++ + E L
Sbjct: 1450 QRNFDKVLAEWKQKYEE-------TQAELEASQKESRSLSTELFKVKNAYEESLDHLETL 1502
Query: 205 KIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHI 264
K EN LQ+ L ++ + + EL K K + K + L + E+ +
Sbjct: 1503 K-------RENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL 1555
Query: 265 KTLTERLLK----MKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAA 320
+ ++L+ + + + I + D E++ N + + L I +
Sbjct: 1556 EHEEGKILRIQLELNQVKSEIDRKIAEKDE---ELDQLKRNHLRVVESMQSTLDAEIRSR 1612
Query: 321 KLNASL---KTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENE--- 374
N +L K +EG+ N++ IQL+ ++ + E ++NL+ Q L+ H ++
Sbjct: 1613 --NDALRIKKKMEGDLNEMEIQLNHANR---QAAEALRNLRNTQGILKDTQLHLDDAIRG 1667
Query: 375 NQKLQQKLKVM---TELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETY 431
L+++L ++ L Q +L L E R E++L E++ + L T
Sbjct: 1668 QDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERV----QLLHTQ 1723
Query: 432 RKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTET 491
+ +++LE I QG++ ++A + A A++ + D A +K +T
Sbjct: 1724 NTSLINTKKKLETDISQIQGEMEDIVQEARN---AEEKAKKAITDAAM-MAEELKKEQDT 1779
Query: 492 ELKFELLEKD 501
E ++K+
Sbjct: 1780 SAHLERMKKN 1789
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/431 (20%), Positives = 180/431 (41%), Gaps = 73/431 (16%)
Query: 76 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 135
K L ++GL E +KL ++ +Q+ ++ +L D E++ L
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQ-----QTLDDLQMEEDKVNT---------LT 1025
Query: 136 RSNSELEDEILCLEKELKEEKSKHSEQDELMADIS---KRIQSLEDESKSLKSQVAEAKM 192
++ ++LE ++ LE L++EK + + + K Q ++++ K Q+ E K+
Sbjct: 1026 KAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNE-KL 1084
Query: 193 TFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVH 252
K F+M+ + KI + AL QLQ+ K+L + ++ EL ++ S+
Sbjct: 1085 KKKEFEMSNLQGKIEDEQALA--IQLQKKIKEL-------QARIEELEEEIEAERASRAK 1135
Query: 253 AEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESE----------NG 302
AE+ +D ++ ++ERL E+ + ++EMN + E
Sbjct: 1136 AEKQRSDLSRELEEISERL-----------EEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 303 AYLDNPPKGALKKLIHA---AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQT 359
+ L + A + HA A+L + +L+ + ++ +K K EL I +L +
Sbjct: 1185 STLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKL-------EKEKSELKMEINDLAS 1237
Query: 360 EQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDE 419
++ +FE + L+ +L + +E + ++ + E E ++DE
Sbjct: 1238 NMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDE 1297
Query: 420 K---ISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLND 476
K +S + + + ++ ++L+ +LE E KA A + R+ D
Sbjct: 1298 KDAMVSQLSRGKQAFTQQIEELKRQLE------------EETKAKSTLAHALQSARHDCD 1345
Query: 477 LRKENAHNRQK 487
L +E Q+
Sbjct: 1346 LLREQYEEEQE 1356
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,897,924
Number of Sequences: 37866
Number of extensions: 2361807
Number of successful extensions: 27099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 511
Number of HSP's successfully gapped in prelim test: 1813
Number of HSP's that attempted gapping in prelim test: 11391
Number of HSP's gapped (non-prelim): 9146
length of query: 761
length of database: 18,247,518
effective HSP length: 110
effective length of query: 651
effective length of database: 14,082,258
effective search space: 9167549958
effective search space used: 9167549958
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.