BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] (1091 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] 2215 0.0 gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens] 2193 0.0 gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens] 2134 0.0 gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ... 100 8e-21 gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H... 79 2e-14 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 60 9e-09 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 60 9e-09 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 60 1e-08 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 57 7e-08 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 55 4e-07 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 1e-06 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 54 1e-06 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 54 1e-06 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 54 1e-06 gi|93141033 PAX interacting protein 1 [Homo sapiens] 52 2e-06 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 52 3e-06 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 52 4e-06 gi|209862789 microtubule associated monoxygenase, calponin and L... 52 4e-06 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 51 7e-06 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 51 7e-06 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 51 7e-06 gi|19924099 synapsin I isoform Ia [Homo sapiens] 50 1e-05 gi|50345997 E1A binding protein p300 [Homo sapiens] 50 2e-05 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 50 2e-05 gi|33286444 mastermind-like 2 [Homo sapiens] 50 2e-05 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 2e-05 gi|148277037 AP2 associated kinase 1 [Homo sapiens] 49 3e-05 gi|73808090 zinc finger protein 207 isoform b [Homo sapiens] 49 3e-05 gi|50345881 cytoplasmic polyadenylation element binding protein ... 49 3e-05 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 49 3e-05 >gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] Length = 1091 Score = 2215 bits (5739), Expect = 0.0 Identities = 1091/1091 (100%), Positives = 1091/1091 (100%) Query: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL Sbjct: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60 Query: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR Sbjct: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120 Query: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ Sbjct: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180 Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV Sbjct: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240 Query: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI Sbjct: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300 Query: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP Sbjct: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360 Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE Sbjct: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420 Query: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV Sbjct: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480 Query: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG Sbjct: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540 Query: 541 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF 600 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF Sbjct: 541 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF 600 Query: 601 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 660 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN Sbjct: 601 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 660 Query: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ Sbjct: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720 Query: 721 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 780 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD Sbjct: 721 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 780 Query: 781 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ 840 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ Sbjct: 781 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ 840 Query: 841 QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN 900 QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN Sbjct: 841 QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN 900 Query: 901 NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS 960 NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS Sbjct: 901 NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS 960 Query: 961 SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS 1020 SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS Sbjct: 961 SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS 1020 Query: 1021 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ 1080 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ Sbjct: 1021 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ 1080 Query: 1081 QRGQGTMNPPH 1091 QRGQGTMNPPH Sbjct: 1081 QRGQGTMNPPH 1091 >gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens] Length = 1137 Score = 2193 bits (5682), Expect = 0.0 Identities = 1091/1137 (95%), Positives = 1091/1137 (95%), Gaps = 46/1137 (4%) Query: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL Sbjct: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60 Query: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR Sbjct: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120 Query: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ Sbjct: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180 Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV Sbjct: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240 Query: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI Sbjct: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300 Query: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP Sbjct: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360 Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE Sbjct: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420 Query: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV Sbjct: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480 Query: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG Sbjct: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540 Query: 541 EKPVVTFKENIKTREVNRDQGRSFPPKE-------------------------------- 568 EKPVVTFKENIKTREVNRDQGRSFPPKE Sbjct: 541 EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL 600 Query: 569 --------------VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 614 VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS Sbjct: 601 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660 Query: 615 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 674 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ Sbjct: 661 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 720 Query: 675 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 734 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK Sbjct: 721 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 780 Query: 735 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 794 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM Sbjct: 781 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 840 Query: 795 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV Sbjct: 841 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 900 Query: 855 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 914 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS Sbjct: 901 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 960 Query: 915 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 974 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN Sbjct: 961 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 1020 Query: 975 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1034 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT Sbjct: 1021 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1080 Query: 1035 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1091 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH Sbjct: 1081 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1137 >gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens] Length = 1049 Score = 2134 bits (5530), Expect = 0.0 Identities = 1049/1049 (100%), Positives = 1049/1049 (100%) Query: 43 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 102 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY Sbjct: 1 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60 Query: 103 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 162 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA Sbjct: 61 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120 Query: 163 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 222 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA Sbjct: 121 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180 Query: 223 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 282 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR Sbjct: 181 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240 Query: 283 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 342 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL Sbjct: 241 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300 Query: 343 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 402 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP Sbjct: 301 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360 Query: 403 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 462 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI Sbjct: 361 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420 Query: 463 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 522 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG Sbjct: 421 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480 Query: 523 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 582 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE Sbjct: 481 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 540 Query: 583 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 642 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG Sbjct: 541 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 600 Query: 643 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 702 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP Sbjct: 601 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 660 Query: 703 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 762 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG Sbjct: 661 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 720 Query: 763 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 822 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE Sbjct: 721 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 780 Query: 823 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 882 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS Sbjct: 781 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 840 Query: 883 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 942 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP Sbjct: 841 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 900 Query: 943 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 1002 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT Sbjct: 901 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 960 Query: 1003 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1062 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM Sbjct: 961 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1020 Query: 1063 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1091 HPGPSALEQLLMQQKQKQQRGQGTMNPPH Sbjct: 1021 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1049 >gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor [Homo sapiens] Length = 1419 Score = 100 bits (249), Expect = 8e-21 Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 16/243 (6%) Query: 7 QYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFK 66 Q L+ + +L D + G ++ R L LY++ ++ D+E++ ++ V+Q LW +AF Sbjct: 591 QELQLSNLLSRDRISPE-GLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFY 649 Query: 67 NQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQL 126 I + K+ N +++ L L+ S F+ LLQ+L + L + + Sbjct: 650 QVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAI 709 Query: 127 GIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTS------QAESYYRHAAQ 180 ++T A++ Q C++ GDIARYR Q S +A S+Y A Sbjct: 710 RSKPLRKTVKYALIS---------AQRCMICQGDIARYREQASDTANYGKARSWYLKAQH 760 Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240 + P NG+PYNQLA+LA L ++YY RS+A P A +L + +++ Sbjct: 761 IAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQM 820 Query: 241 KTK 243 + K Sbjct: 821 EKK 823 Score = 36.6 bits (83), Expect = 0.13 Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 29/147 (19%) Query: 249 FIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLL--FQKAFNSQQLVHVTVINLFQLH 306 FI +F+ HG ++ +E + EK+ ++F+ LL S +++ + IN+F +H Sbjct: 892 FILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVH 951 Query: 307 H--LRD-FSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPL-------------QNE 350 + L+D FS E Q L LA+F S L C C L Q++ Sbjct: 952 NSQLKDCFSEECRSVIQEQAAALG----LAMF-SLLVRRCTCLLKESAKAQLSSPEDQDD 1006 Query: 351 SQEESYNAYP------LPAVKVSMDWL 371 + +++ LP+VKV DW+ Sbjct: 1007 QDDIKVSSFVPDLKELLPSVKVWSDWM 1033 >gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo sapiens] Length = 1016 Score = 79.0 bits (193), Expect = 2e-14 Identities = 62/225 (27%), Positives = 106/225 (47%), Gaps = 29/225 (12%) Query: 33 RQALQDLYQK-MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANL 91 R L++L K M + ++Y +K E+ LW + I ++ K+ + RS ++ Sbjct: 56 RNKLRELCVKLMFLHPVDYG--RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAY 111 Query: 92 SLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS-- 146 L A GFY LL + + + ++L C + + + T ++ KP S+S Sbjct: 112 RTHLVAGIGFYQHLLLYIQSHYQLELQCCIDWTHV---------TDPLIGCKKPVSASGK 162 Query: 147 ----CSYICQHCLVHLGDIARYRNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILA 196 C CLV+LGD++RY+N+ + AE +Y A + P G P+NQL LA Sbjct: 163 EMDWAQMACHRCLVYLGDLSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLA 222 Query: 197 SSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVK 241 SK ++ ++ Y R I + F A NL++ KA + ++K Sbjct: 223 GSKYYNVEAMYCYLRCIQSEVSFEGAYGNLKRLYDKAAKMYHQLK 267 Score = 41.6 bits (96), Expect = 0.004 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%) Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 407 LPAVKV +DWLR P + Q +W L LLN + P +DL Sbjct: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713 Query: 408 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 460 P LPE+ L+ LR + R +F ++ +E +R + Sbjct: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770 Query: 461 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 508 S G +IA Q ++Q EVG + I + + L ++A+ + +E Sbjct: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 60.5 bits (145), Expect = 9e-09 Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%) Query: 587 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 645 P+ +TP +S P+ G P P G P + PP G GY P G Sbjct: 373 PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426 Query: 646 PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 688 P + +Q A S G Q PY QQ PSG P P Q P Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484 Query: 689 QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 747 S QPPSQ P AQP+ Q Q Q L Q Q P P+ PPH Y Sbjct: 485 YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536 Query: 748 ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 807 ++ Q P QP Y Q P Q P QQQP + P Sbjct: 537 QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568 Query: 808 MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 867 + P+ + + R Q+ + D G ++ P M Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620 Query: 868 EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 926 K E + L S SS L+G + ++ V ++SS + +P+ +P Sbjct: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680 Query: 927 ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 980 L + +P PAS S SP + + +P PP+ +S+ P Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740 Query: 981 SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 1035 N I +R + P G SA S + S Q T G++ Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788 Score = 36.2 bits (82), Expect = 0.17 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%) Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 649 P Q S+ P H ++ P+R +PPP Y + P + GSG AG P Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252 Query: 650 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 706 P++ + A + S ++QQR G GP G QP + L L P+ Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303 Query: 707 A 707 + Sbjct: 304 S 304 Score = 33.1 bits (74), Expect = 1.5 Identities = 91/420 (21%), Positives = 139/420 (33%), Gaps = 54/420 (12%) Query: 558 RDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 617 + Q +S PP+ SQ + P + P+Q S +Q HP + PP S+P Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ----QHPQSQPPY-SQPQ 555 Query: 618 FPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 677 P P PA P T Q A+ Q Q+ + YSQQR Sbjct: 556 AQSPYQQQQPQQ----------PA----PSTLSQQAAYP----QPQSQQSQQTAYSQQRF 597 Query: 678 SGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL--GKS 735 P ++Q SQ S +TS Q L +Q+ + ++ L G Sbjct: 598 PPPQELSQDSFGSQASSAPSMTS---SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654 Query: 736 PPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS-LQPPVM 794 G + + + NP Q P P+ + P PS + P Sbjct: 655 GALSPGVSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGP----SPSPVGSPAS 705 Query: 795 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854 Q + P + P N P + P DS + N+S +AQ +R + P Sbjct: 706 VAQSRSGPLSPAAV-PGNQMPP--RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762 Query: 855 FRPEQDPV--PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN-QERYPNNSMFNEVYGKN 911 P+ PR P + +S G Q YP +N + N Sbjct: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN 822 Query: 912 LTSSSKA-ELSPSMAPQETSLYSLFEGTPWSP---SLPASSDHSTPASQSPHSSNPSSLP 967 S+ A ++P A + G P P +LP P+ N +++P Sbjct: 823 YPSAGMAGGINPMGAGGQ------MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMP 876 Score = 31.6 bits (70), Expect = 4.3 Identities = 37/186 (19%), Positives = 64/186 (34%), Gaps = 21/186 (11%) Query: 642 GVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSL 701 G + P T T PAG G Q+ P+ R P QQ+ PP Sbjct: 1432 GNAYPATATAATERRPAG-----GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486 Query: 702 PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQL-----W- 755 + AQ + Q + + ++ + + P +H + + ++ W Sbjct: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWP 1546 Query: 756 -----NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFE--PSLQPPVMQQQPLEKKMKPFPM 808 PP GP + P+ +P Q P + P + P +P+E + P Sbjct: 1547 SHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSP-SK 1603 Query: 809 EPYNHN 814 P+ H+ Sbjct: 1604 SPFLHS 1609 Score = 31.2 bits (69), Expect = 5.6 Identities = 48/226 (21%), Positives = 79/226 (34%), Gaps = 20/226 (8%) Query: 671 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730 PYS+ G G + GP+Q P P + +P + A Q P+ Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316 Query: 731 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP--YYLQTQDPIKLFEP 787 + SP + QQ QQ N QG P G P +Q Y Q Q+ + + Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDG 1375 Query: 788 SLQPPVM--------------QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMAD 833 + PP Q QP ++++ P +P + + P+ + Y A Sbjct: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAY 1435 Query: 834 NRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELM 879 + A G ++ F+ +D V P + P ++M Sbjct: 1436 PATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 60.5 bits (145), Expect = 9e-09 Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%) Query: 587 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 645 P+ +TP +S P+ G P P G P + PP G GY P G Sbjct: 373 PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426 Query: 646 PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 688 P + +Q A S G Q PY QQ PSG P P Q P Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484 Query: 689 QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 747 S QPPSQ P AQP+ Q Q Q L Q Q P P+ PPH Y Sbjct: 485 YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536 Query: 748 ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 807 ++ Q P QP Y Q P Q P QQQP + P Sbjct: 537 QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568 Query: 808 MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 867 + P+ + + R Q+ + D G ++ P M Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620 Query: 868 EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 926 K E + L S SS L+G + ++ V ++SS + +P+ +P Sbjct: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680 Query: 927 ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 980 L + +P PAS S SP + + +P PP+ +S+ P Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740 Query: 981 SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 1035 N I +R + P G SA S + S Q T G++ Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788 Score = 36.2 bits (82), Expect = 0.17 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%) Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 649 P Q S+ P H ++ P+R +PPP Y + P + GSG AG P Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252 Query: 650 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 706 P++ + A + S ++QQR G GP G QP + L L P+ Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303 Query: 707 A 707 + Sbjct: 304 S 304 Score = 33.1 bits (74), Expect = 1.5 Identities = 91/420 (21%), Positives = 139/420 (33%), Gaps = 54/420 (12%) Query: 558 RDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 617 + Q +S PP+ SQ + P + P+Q S +Q HP + PP S+P Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ----QHPQSQPPY-SQPQ 555 Query: 618 FPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 677 P P PA P T Q A+ Q Q+ + YSQQR Sbjct: 556 AQSPYQQQQPQQ----------PA----PSTLSQQAAYP----QPQSQQSQQTAYSQQRF 597 Query: 678 SGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL--GKS 735 P ++Q SQ S +TS Q L +Q+ + ++ L G Sbjct: 598 PPPQELSQDSFGSQASSAPSMTS---SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654 Query: 736 PPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS-LQPPVM 794 G + + + NP Q P P+ + P PS + P Sbjct: 655 GALSPGVSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGP----SPSPVGSPAS 705 Query: 795 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854 Q + P + P N P + P DS + N+S +AQ +R + P Sbjct: 706 VAQSRSGPLSPAAV-PGNQMPP--RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762 Query: 855 FRPEQDPV--PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN-QERYPNNSMFNEVYGKN 911 P+ PR P + +S G Q YP +N + N Sbjct: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN 822 Query: 912 LTSSSKA-ELSPSMAPQETSLYSLFEGTPWSP---SLPASSDHSTPASQSPHSSNPSSLP 967 S+ A ++P A + G P P +LP P+ N +++P Sbjct: 823 YPSAGMAGGINPMGAGGQ------MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMP 876 Score = 33.1 bits (74), Expect = 1.5 Identities = 46/199 (23%), Positives = 73/199 (36%), Gaps = 16/199 (8%) Query: 671 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730 PYS+ G G + GP+Q P P + +P + A Q P+ Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316 Query: 731 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQPYYLQTQDPIKLFEPSL 789 + SP + QQ QQ N QG P G P +Q Q Q + P Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375 Query: 790 QPPVMQQQPLE--------KKMKPFPMEPYNH-NPSEVKVPEFYWDSSY---SMADNRSV 837 +P + P + K K P P +H P+ V+ P D ++ S+ + V Sbjct: 1376 RPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPV 1435 Query: 838 MAQQANIDRRGKRSPGVFR 856 + Q+ + + +P +R Sbjct: 1436 LKQRRRLTMKDIGTPEAWR 1454 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 60.1 bits (144), Expect = 1e-08 Identities = 93/385 (24%), Positives = 144/385 (37%), Gaps = 58/385 (15%) Query: 626 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 685 PPP M + P T LQ A Q Q +Q + QQ+ + Q Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182 Query: 686 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 745 QQ Q +QQ Q Q QLQ Q QQQQ K HH QQ Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231 Query: 746 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805 QQ +QL Q+Q L + +Q Q Q ++ P QPP+ Q QP + P Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287 Query: 806 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 861 ++ +H P+ +A N+ +Q + + + PG Q P Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344 Query: 862 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNL 912 V + P + + ++ + + + ++ + G ++Q P + + G+ + Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--MLSSPSPGQQV 402 Query: 913 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS--SNPSSLPSSP 970 + P +PQ P PS +S+ S+ + SP S +PS PS Sbjct: 403 QTPQSMPPPPQPSPQ-----------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 451 Query: 971 P----THNHNSVPFSNFGPIGTPDN 991 P T + SVP + GP+ TP N Sbjct: 452 PVTARTPQNFSVP--SPGPLNTPVN 474 Score = 37.7 bits (86), Expect = 0.060 Identities = 62/268 (23%), Positives = 97/268 (36%), Gaps = 39/268 (14%) Query: 551 IKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFP 610 ++ ++ + Q + + +++Q +++ P+ + + P P Q H P P Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQP 305 Query: 611 PLP----SRPGFPPPTYVIPPPVAFSMGSG----YTFP--AGVSVPGTFLQPTAH----- 655 P ++P PP P V+ + YT P V P QP Sbjct: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365 Query: 656 -------SPAGNQVQAG---KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 705 + A V G QS +P PS PG Q P QS PP QP + P QP Sbjct: 366 QQTAVQTAQAAQMVAPGVQVSQSSLPMLSS-PS-PGQQVQTP-QSMPPPPQP-SPQPGQP 421 Query: 706 TAQSTSQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQ 759 ++Q S + + SP+ +P+ P P + Q + L NP Sbjct: 422 SSQPNSNVS----SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477 Query: 760 VQGPLGKIMPVKQPYYLQTQDPIKLFEP 787 V P G +Q Y + + K EP Sbjct: 478 VMSPAGSSQAEEQQYLDKLKQLSKYIEP 505 Score = 33.5 bits (75), Expect = 1.1 Identities = 48/225 (21%), Positives = 80/225 (35%), Gaps = 14/225 (6%) Query: 565 PPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV 624 PP V+ Q + ++T V A+ + Q S S + P + + PPP Sbjct: 357 PP--VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP 414 Query: 625 IPPPVAFSMGSGYTFPAG-VSVPGTFLQPTAHSPAGNQVQAGKQSHI----PYSQQRPSG 679 P P S +G P +FL + P+ + V A + P P Sbjct: 415 SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVN 474 Query: 680 PGPMNQGPQQSQPPSQQPLTSLP-----AQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 734 P + SQ QQ L L +P + +++ ++ S K++ + Sbjct: 475 PSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILT 534 Query: 735 SPPHHSGFQQYQQAD-ASKQLWNPPQV-QGPLGKIMPVKQPYYLQ 777 P + Q+ + A ++L N V P + P KQ Y Q Sbjct: 535 DPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQ 579 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 57.4 bits (137), Expect = 7e-08 Identities = 147/619 (23%), Positives = 220/619 (35%), Gaps = 122/619 (19%) Query: 433 NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL 492 +LD +K + G+K G+ I Q R S+ ++ P I+ + E K + E+ Sbjct: 619 SLDINK----LPGEKLGRVVHIIQSREPSL----KNSNPDEIEIDFETLKPSTLRELERY 670 Query: 493 ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK 552 + + ++ + ++ +A GS +K S+ S+ + + E+ + Sbjct: 671 VTSCLRKKRK----PQAEKVDVIA--GSSKMKGFSSSESESSSESSSSDS------EDSE 718 Query: 553 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL 612 T + + + P +E K + +A PV Q P PP Sbjct: 719 TEMAPKSKKKGHPGREQKKHHHHHHQQMQQA-PAPVPQQP-----------------PPP 760 Query: 613 PSRPGFPPP----TYVIPPPVAFSMGSGYTFPAGVSVPGTF-------LQP----TAHSP 657 P +P PPP PPP SM PA S P F L+P + P Sbjct: 761 PQQPPPPPPPQQQQQPPPPPPPPSMPQ-QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDP 819 Query: 658 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP--SQQPLTSLP----AQPTAQSTS 711 G+ Q H+P +P P + Q P+ S PP +Q + S P A P S Sbjct: 820 IGHFTQ--PILHLP----QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873 Query: 712 QLQVQALTQQQQSPTKAVPALGKSP--PHHSGFQQYQQADASKQLWNPP----QVQGPLG 765 + AL + P PAL ++P P Q Q ++ PP Q+Q L Sbjct: 874 SNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ 933 Query: 766 KIMPVKQPYYL------QTQDPIKL---FEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS 816 ++ V+ P L Q+Q P L PS+Q + QQ P +P P H P Sbjct: 934 QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP 993 Query: 817 EVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEK------- 869 V S + QQ G++ P P Q P+ + Sbjct: 994 PRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPP----PPQPAKPQQVIQHHHSPRHH 1049 Query: 870 --------SLLEKPSELMSHS---SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 918 L E PS LM HS S F SLT S Q+ + L ++S Sbjct: 1050 KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK-------QELRAASVV 1102 Query: 919 ELSPSMAPQETSLYS-LFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP---PTHN 974 + P + +E ++S + P+SPSL P P LP P P Sbjct: 1103 QPQPLVVVKEEKIHSPIIRSEPFSPSL-----RPEPPKHPESIKAPVHLPQRPEMKPVDV 1157 Query: 975 HNSV---PFSNFGPIGTPD 990 V P N P G PD Sbjct: 1158 GRPVIRPPEQNAPPPGAPD 1176 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 55.1 bits (131), Expect = 4e-07 Identities = 130/536 (24%), Positives = 191/536 (35%), Gaps = 88/536 (16%) Query: 607 GAFPPLPSRPGFPPPTYVIPPPVAFSMGS---GYTFPAGVSVPGTF-LQPTAHSPAGNQV 662 G++P S P PPP P A + G+ G AG+ + Q A SPA Sbjct: 377 GSYPEYSS-PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAA 435 Query: 663 QAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQP-LTSLPAQPTAQSTSQLQVQAL 718 Q ++SH S P PGP +QG ++P L + + P +Q Sbjct: 436 Q--QRSHPAMS---PGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490 Query: 719 TQQQQSPTK-AVPALGKSPPHHSGFQQYQQADASKQLWN------PPQV--QGPLGKIMP 769 + P + + G++P +G Q QQ D+ W PPQ QG G Sbjct: 491 SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ 550 Query: 770 VKQPYYLQTQDPIKL-----FEPS-----LQPPV-MQQQPLEKKMKPFPMEPYNHNPSEV 818 +QPYY Q P L + PS QP M Q+ + +P P+ P N ++ Sbjct: 551 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP-PLAPGKPNHEDL 609 Query: 819 KV-----PEFYWDSSYSMAD---------NRSVMAQQANIDRRGKRSP--GVFRPEQDP- 861 + P D S S+ D + +V A + + + +P F P P Sbjct: 610 NLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPH 669 Query: 862 ---VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 918 +P P PS + S S S +G ++ P + M + G SSS Sbjct: 670 LSSIPGGP-------SPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHP 721 Query: 919 ELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV 978 LS S PQE + GT +P + T S SPH S P + + S Sbjct: 722 ALSQSPMPQERGFMA---GTQRNPQMAQYGPQQTGPSMSPHPS-PGGQMHAGISSFQQSN 777 Query: 979 PFSNFGP----IGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1034 +GP G N R PA G + + S S + + Sbjct: 778 SSGTYGPQMSQYGPQGNYSR---------PPAYSG-----VPSASYSGPGPGMGISANNQ 823 Query: 1035 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP 1090 G GPS + AV + + S + P P + + Q+G M PP Sbjct: 824 MHGQGPS-QPCGAVPLGRMPS--AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP 876 Score = 44.7 bits (104), Expect = 5e-04 Identities = 80/319 (25%), Positives = 115/319 (36%), Gaps = 37/319 (11%) Query: 439 GHQGITGD-KEGQQRRIRQQ----RLISIGKWIADNQPRLIQCENEVGKLLFITEI-PEL 492 G QG++G ++GQQ QQ L +++ + Q + ++ + + T P L Sbjct: 540 GQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPL 599 Query: 493 ILEDPSEAKENLILQE--------TSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPV 544 P+ NLI QE + I+ L L S +S S + S+ D Sbjct: 600 APGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQ 659 Query: 545 VTFKENIKTREVNRDQGRSFPPKEVKS---QTELRKTPVSEARKTPVTQTPTQASNSQFI 601 F + + G S P V S + R P+S A P +Q P Q SQ Sbjct: 660 SPFSPHASPHLSSIPGGPS--PSPVGSPVGSNQSRSGPISPA-SIPGSQMPPQPPGSQSE 716 Query: 602 PIHHPG-AFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 660 HP + P+P GF T P + G G + P H G Sbjct: 717 SSSHPALSQSPMPQERGFMAGTQRNPQMAQY----------GPQQTGPSMSP--HPSPGG 764 Query: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQ--QSQPPSQQPLTSLP-AQPTAQSTSQLQVQA 717 Q+ AG S + GP GPQ S+PP+ + S + P Q Sbjct: 765 QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQM 824 Query: 718 LTQQQQSPTKAVPALGKSP 736 Q P AVP LG+ P Sbjct: 825 HGQGPSQPCGAVP-LGRMP 842 Score = 33.1 bits (74), Expect = 1.5 Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 39/225 (17%) Query: 604 HHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 663 H PG +P P+ Y PP G Y + Q ++ Sbjct: 1303 HQPGLYPQQPNYKRHMDGMY--GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP 1360 Query: 664 AGKQSHIPYSQQRPSGPGPMNQ---GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720 Q PYS++R GPG + PQ P Q + P Q + + + + Sbjct: 1361 IQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNR 1420 Query: 721 Q-QQSPTKAVPALGKS------------------PPHHSGFQQYQQADASKQ-LWNPPQV 760 Q PT+A P G + P H S Q Y + AS Q + PP Sbjct: 1421 QGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPP-- 1478 Query: 761 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805 QP Y QT + P Q+ LE +M P Sbjct: 1479 -----------QPSY-QTPPSLPNHISRAPSPASFQRSLENRMSP 1511 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 53.5 bits (127), Expect = 1e-06 Identities = 119/459 (25%), Positives = 169/459 (36%), Gaps = 86/459 (18%) Query: 571 SQTELRKTPVSEARKTPVTQT-PTQASNSQFIPIHHPGAFPP-----LPSRPGFPP---- 620 S T+ R P + TP+ T P + +P+ P P LPS P PP Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369 Query: 621 PTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP----AGNQVQAGKQSHIPYSQQR 676 P+ PP A S T P + VP + P+ +P A + +QA P Q Sbjct: 370 PSMTTPPMQA--PPSLQTIPP-IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426 Query: 677 PSGPGPMNQGPQQSQ----------------PPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720 S + P+Q+Q PP Q PL SLPA P Q++ V L+ Sbjct: 427 HSF---LTMSPRQTQASLTSPSRPASTPPDSPPLQAPL-SLPASPPLQTSLSPAVSPLSS 482 Query: 721 QQQ-SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQ 779 P +A+ +L P QA S + P + Q L P L T Sbjct: 483 PLTIHPLQALSSLASHSP---------QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533 Query: 780 DPIKLFEPSLQPPVMQQQP-------LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMA 832 L PSL PP +Q LE P P P PS + P SS + Sbjct: 534 PLENL--PSLAPPPLQTASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIATP 590 Query: 833 DNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFS 892 ++ A A+ +G SP + P P P+ P +L P + + L+ + Sbjct: 591 PPQAPPAL-ASPPLQGLPSPPL-SPLATPPPQAPPXLAL--PPLQAPPSPPASPPLSPLA 646 Query: 893 LNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHST 952 + PN + + +A SP +P + +S P+ P S +T Sbjct: 647 TPSPQAPNALAVHLL---------QAPFSPPPSPPVQAPFS-------PPASPPVSPSAT 690 Query: 953 PASQSPHS--SNPSSLPSSPPTHNHNSVPFSNFGPIGTP 989 P SQ+P S + P +P SPP S P S P TP Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPA----SPPMS---PSATP 722 Score = 43.1 bits (100), Expect = 0.001 Identities = 83/378 (21%), Positives = 127/378 (33%), Gaps = 61/378 (16%) Query: 628 PVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGP 687 P ++ +G PGT A + G P ++ RP GP Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210 Query: 688 QQSQPPSQQPLTSLPAQPTA----QSTSQLQVQALTQQQQSPTKAVPALGKSP--PHHSG 741 S+ + +P + +P+A Q + + + SP ++ P+ +P P H Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270 Query: 742 FQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY---LQTQDPIKLFEPSLQPPVMQQQP 798 Q Q PPQV P P P L T P + PP P Sbjct: 271 ----QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326 Query: 799 LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPE 858 L + P P P +P + + A + SP P Sbjct: 327 LPATLPPSP-------PLATPLP-------------LAPPSPSAPPSLQTLPSPPATPPS 366 Query: 859 QDP----VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 914 Q P P M SL P + HS + SL + P+ + + Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL-------QAPPSPLALSSLQATTSLG 419 Query: 915 SSKAELSPS---MAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPP 971 S + + S M+P++T + + SPS PAS+ +P Q+ P SLP+SPP Sbjct: 420 SPTLQATHSFLTMSPRQT------QASLTSPSRPASTPPDSPPLQA-----PLSLPASPP 468 Query: 972 THNHNSVPFSNFGPIGTP 989 S S P+ +P Sbjct: 469 LQTSLSPAVS---PLSSP 483 Score = 35.4 bits (80), Expect = 0.30 Identities = 65/245 (26%), Positives = 86/245 (35%), Gaps = 39/245 (15%) Query: 577 KTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPP------PVA 630 +TP S A TP Q P ++ + P PL + P PP +PP P A Sbjct: 582 ETPSSIA--TPPPQAPPALASPPLQGLPSP-PLSPLATPPPQAPPXLALPPLQAPPSPPA 638 Query: 631 FSMGSGYTFP---AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQR-----PSGPGP 682 S P A ++ LQ P VQA P+S PS P Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA------PFSPPASPPVSPSATPP 692 Query: 683 MNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGF 742 P + PP Q P S PA P ++ QA P + P+ SPP Sbjct: 693 SQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP----- 746 Query: 743 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIK-LFEPSLQ-PPVMQQQPLE 800 S PP+V PL P++ P P+ L +P Q PP + PL+ Sbjct: 747 -------MSPSATPPPRVP-PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798 Query: 801 KKMKP 805 P Sbjct: 799 ALPSP 803 Score = 35.4 bits (80), Expect = 0.30 Identities = 36/142 (25%), Positives = 47/142 (33%), Gaps = 11/142 (7%) Query: 579 PVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP--------PPTYVIPPPVA 630 P+S + P P A+ +P P + P PS P PP V P P A Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774 Query: 631 FSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQS 690 S P + P P P+ A P+S P+ P Q+ Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQA 831 Query: 691 QPPSQQPLTSLPAQPTAQSTSQ 712 P PL +P P A T Q Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQ 853 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 53.5 bits (127), Expect = 1e-06 Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%) Query: 557 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615 NR S P P++ +S ++ + P Q PT + + P P P LP+ Sbjct: 154 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 209 Query: 616 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 675 PG P +PP GS P P PTA P +Q H Q Sbjct: 210 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 255 Query: 676 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 735 RP P P P S P QPLT QP+A S +Q P G+ Sbjct: 256 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 296 Query: 736 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 789 PP Q Q + PPQ Q PLG P+ T + + +L Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 353 Query: 790 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 849 Q QQ P E+ + P P+ Sbjct: 354 QS---QQPPREQPLPPAPLA---------------------------------------- 370 Query: 850 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 909 P + P P+P++P ++ H + FS+N P ++ Sbjct: 371 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 415 Query: 910 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 969 K L+S S PS P L + P SP+ P S P S P+ L Sbjct: 416 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474 Query: 970 PPTHNHNSVPFSNFGP 985 P PF GP Sbjct: 475 APQPPFAQHPFVPGGP 490 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 53.5 bits (127), Expect = 1e-06 Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%) Query: 557 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615 NR S P P++ +S ++ + P Q PT + + P P P LP+ Sbjct: 708 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 763 Query: 616 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 675 PG P +PP GS P P PTA P +Q H Q Sbjct: 764 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 809 Query: 676 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 735 RP P P P S P QPLT QP+A S +Q P G+ Sbjct: 810 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 850 Query: 736 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 789 PP Q Q + PPQ Q PLG P+ T + + +L Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 907 Query: 790 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 849 Q QQ P E+ + P P+ Sbjct: 908 QS---QQPPREQPLPPAPLA---------------------------------------- 924 Query: 850 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 909 P + P P+P++P ++ H + FS+N P ++ Sbjct: 925 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 969 Query: 910 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 969 K L+S S PS P L + P SP+ P S P S P+ L Sbjct: 970 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028 Query: 970 PPTHNHNSVPFSNFGP 985 P PF GP Sbjct: 1029 APQPPFAQHPFVPGGP 1044 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 53.5 bits (127), Expect = 1e-06 Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%) Query: 557 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615 NR S P P++ +S ++ + P Q PT + + P P P LP+ Sbjct: 708 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 763 Query: 616 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 675 PG P +PP GS P P PTA P +Q H Q Sbjct: 764 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 809 Query: 676 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 735 RP P P P S P QPLT QP+A S +Q P G+ Sbjct: 810 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 850 Query: 736 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 789 PP Q Q + PPQ Q PLG P+ T + + +L Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 907 Query: 790 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 849 Q QQ P E+ + P P+ Sbjct: 908 QS---QQPPREQPLPPAPLA---------------------------------------- 924 Query: 850 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 909 P + P P+P++P ++ H + FS+N P ++ Sbjct: 925 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 969 Query: 910 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 969 K L+S S PS P L + P SP+ P S P S P+ L Sbjct: 970 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028 Query: 970 PPTHNHNSVPFSNFGP 985 P PF GP Sbjct: 1029 APQPPFAQHPFVPGGP 1044 >gi|93141033 PAX interacting protein 1 [Homo sapiens] Length = 1069 Score = 52.4 bits (124), Expect = 2e-06 Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 14/188 (7%) Query: 657 PAGNQVQAGKQSHI-PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 715 P Q Q +Q+H +SQQ+ P PQQ P QQ Q QLQ Sbjct: 447 PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQ 506 Query: 716 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY 775 L QQQ L + HS QQ QQ +Q Q ++ P+ Sbjct: 507 HQLQQQQ---------LAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHL 557 Query: 776 LQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE--FYWDSSYSMAD 833 QT ++ P QPP QQQ + P + + H+P+ V++PE F +++AD Sbjct: 558 SQTSQALQHQVPPQQPP-QQQQQQQPPPSPQQHQLFGHDPA-VEIPEEGFLLGCVFAIAD 615 Query: 834 NRSVMAQQ 841 M+ + Sbjct: 616 YPEQMSDK 623 Score = 44.7 bits (104), Expect = 5e-04 Identities = 46/154 (29%), Positives = 65/154 (42%), Gaps = 24/154 (15%) Query: 653 TAHSPAGN---QVQAGKQSH-----IPYSQQRPSGPGPMNQGPQQSQPPSQQ-PLTSLPA 703 T +P N QV +Q H + +SQ + + M Q QQ+Q QQ P+ L Sbjct: 362 TLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP 421 Query: 704 QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGP 763 Q Q+ L QQQQ P + PPH QQ QQ A ++ Q+Q P Sbjct: 422 Q---------QIMQLQQQQQQQISQQP-YPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFP 471 Query: 764 LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 797 ++ P +Q + Q Q +P Q +QQQ Sbjct: 472 QQQLHPPQQLHRPQQQ-----LQPFQQQHALQQQ 500 Score = 32.7 bits (73), Expect = 1.9 Identities = 50/291 (17%), Positives = 91/291 (31%), Gaps = 27/291 (9%) Query: 689 QSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPT------KAVPALGKSPPHHSGF 742 QS S+ T PA T ++ + A QQ P+ + + A K+ Sbjct: 320 QSSERSEMIATWSPAVRTLRNITN---NADIQQMNRPSNVAHILQTLSAPTKNLEQQVNH 376 Query: 743 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 802 Q +A+ L++ +V + +Q Q Q P+ +P + QQQ + Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQIS 436 Query: 803 MKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPV 862 +P+P +P + P A QQ ++ P Q + Sbjct: 437 QQPYPQQPPH--------PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQL 488 Query: 863 PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP 922 + +L ++ +L H L Q++ + + + + + Sbjct: 489 QPFQQQHALQQQFHQLQQH----------QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538 Query: 923 SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTH 973 M Q+ + P + H P Q P P SP H Sbjct: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH 589 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 52.0 bits (123), Expect = 3e-06 Identities = 59/217 (27%), Positives = 72/217 (33%), Gaps = 32/217 (14%) Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 665 P+ P PPP ++ PPP + G P G P Q +P G+ V G Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468 Query: 666 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 722 P P P P Q P PP QQ P P S+ QQ Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528 Query: 723 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 782 + T G PP +QQ Q A A+ PQ+QG P P Q P+ Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577 Query: 783 KLFEPSLQPPVMQQQPLEKKM-------KPFPMEPYN 812 P PP P M P PM+P N Sbjct: 578 ---PPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSN 611 Score = 33.9 bits (76), Expect = 0.86 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 6/49 (12%) Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFP 640 P N +P+ PG PPLP PG PPP PPP S G Y P Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAGMMYAPP 600 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 51.6 bits (122), Expect = 4e-06 Identities = 108/471 (22%), Positives = 151/471 (32%), Gaps = 87/471 (18%) Query: 591 TPTQASN-SQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPA-GVSVP 646 +P+ AS+ S F P + P A+ P P PG P P+ Y+ P A S T PA P Sbjct: 1547 SPSAASDASGFSPGYSP-AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSP 1605 Query: 647 GTFL-QPTAHSPAGNQVQAGKQSHIPYS-QQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQ 704 G + Q ++SP S+ P S P+ P P S TS Sbjct: 1606 GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665 Query: 705 PTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPL 764 PT+ S S T SPT SP + Y S +P P Sbjct: 1666 PTSPSYSP------TSPSYSPT--------SPSYSPTSPSYSPTSPSYSPTSPS--YSPT 1709 Query: 765 GKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFY 824 P Y T PS P P P N+ P+ Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSP---TSPNYTPT-------- 1758 Query: 825 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 884 SYS SP + P P PS + S Sbjct: 1759 -SPSYS------------------PTSPSYSPTSPNYTPTSPNYSP--TSPSYSPTSPSY 1797 Query: 885 FLSLTGFSLNQERY-PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPS 943 + +S + RY P + + +S S + SPS +P TP SPS Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTP------SSPSYSPSSPSYSPTSPKY------TPTSPS 1845 Query: 944 LPASSDHSTPASQSPHSSNPSSLPSSP-------------PTHNHNSVPFSNFGPIGTPD 990 SS TP S ++P P+SP P ++ S +S P+ TP Sbjct: 1846 YSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTP- 1904 Query: 991 NRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPS 1041 T+ ++ P Y + + + + ST S T G+ P+ Sbjct: 1905 -----TSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950 Score = 46.2 bits (108), Expect = 2e-04 Identities = 110/536 (20%), Positives = 167/536 (31%), Gaps = 48/536 (8%) Query: 526 VLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARK 585 +++ +R+ N DTG +F+E + G S P K V L + + Sbjct: 1411 LMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGC 1470 Query: 586 TPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGF---PPPTYVIPPPVA-FSMGSGYTFPA 641 + + IP + PG P+ F P P I P + ++ G+ + A Sbjct: 1471 FDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGA 1530 Query: 642 GVSVPGTFLQPTA--HSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPL 698 G+ + P A SP+ +G + P P PG + GP PS Sbjct: 1531 WSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPG--SPGPSSPYIPSPGGA 1588 Query: 699 TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQ-QYQQADASKQLWNP 757 S PT+ + T Q S + P+ + P +S Y S +P Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSP 1648 Query: 758 PQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSE 817 P P Y T PS P P P +PS Sbjct: 1649 SY--SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1706 Query: 818 VKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 877 Y +S S + + + S P P P+ Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPT-----------SPNY 1755 Query: 878 LMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEG 937 + S + +S Y TS + + SPS +P S Sbjct: 1756 TPTSPSYSPTSPSYSPTSPNYTP------------TSPNYSPTSPSYSPTSPSY------ 1797 Query: 938 TPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP------PTHNHNSVPFSNFGPIGTPDN 991 +P SPS SS TP S + S+PS PSSP P + S +S P TP + Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS 1857 Query: 992 -RDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSS 1046 + T+ ++ P Y T + S S +T P +S Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTS 1913 >gi|209862789 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 1 [Homo sapiens] Length = 2002 Score = 51.6 bits (122), Expect = 4e-06 Identities = 109/481 (22%), Positives = 182/481 (37%), Gaps = 84/481 (17%) Query: 496 DPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTRE 555 D ++ +E++ + + A DG PG T L ++ + P Sbjct: 1068 DENDLEEDVDSEPAEIEGEAAEDGDPG-----DTGAELDDDQHWSDSPS----------- 1111 Query: 556 VNRDQGRSFP-PKEVKSQTELR------KTPVSE-------ARKTPVTQTPTQASNSQFI 601 + D+ P P E +++ ELR K P S ++ T ++P Q S FI Sbjct: 1112 -DADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSP-QESALLFI 1169 Query: 602 PIHHPGA----FPPLPSRPGFPPPTY-VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 656 P+H P PP+P+ P + P P+ P+ + HS Sbjct: 1170 PVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKA--------VHS 1221 Query: 657 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 716 P +Q ++ P S P P P + PPS P+ S P QP+ ++T Sbjct: 1222 PIRSQPVTLPEARTPVS---PGSPQPQPPVAASTPPPSPLPICSQP-QPSTEAT------ 1271 Query: 717 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 776 + QSP + PA K+ + Q+D +L +P V L + V++ +++ Sbjct: 1272 -VPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEE-FWM 1329 Query: 777 QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 836 ++ + + + P+++ P P P P+ V + S D Sbjct: 1330 KSAEIRR---------SLGLTPVDRSKGPEPSFP---TPAFRPVSLKSYSVEKSPQDEGL 1377 Query: 837 VMAQQANIDRRGKRSPGVFRPEQDPV----PRMPFEKSLLEKPSELMS-HSSSFLSLTGF 891 + + +I +R G+ +PE +P+ PR P ++ L E SSS L L G Sbjct: 1378 HLLKPLSIPKR----LGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGS 1433 Query: 892 SLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSL-YSLFEGTPWS----PSLPA 946 S N + + S FN LT S P + +L L E P + P LPA Sbjct: 1434 SSNMKTLGSQS-FNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPA 1492 Query: 947 S 947 + Sbjct: 1493 T 1493 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 50.8 bits (120), Expect = 7e-06 Identities = 52/190 (27%), Positives = 64/190 (33%), Gaps = 22/190 (11%) Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 665 P+ P PPP ++ PPP + G P G P Q +P G+ V G Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468 Query: 666 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 722 P P P P Q P PP QQ P P S+ QQ Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528 Query: 723 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 782 + T G PP +QQ Q A A+ PQ+QG P P Q P+ Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577 Query: 783 KLFEPSLQPP 792 P PP Sbjct: 578 PPGAPPPPPP 587 Score = 31.6 bits (70), Expect = 4.3 Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 6/43 (13%) Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMG 634 P N +P+ PG PPLP PG PPP PPP S G Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAG 594 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 50.8 bits (120), Expect = 7e-06 Identities = 88/366 (24%), Positives = 125/366 (34%), Gaps = 57/366 (15%) Query: 463 GKWIADNQPRLIQCENEVGKLLFI----TEIPELILEDPSEAKENLILQETSVIESLAAD 518 GK I N+ +VG +FI EI E +L D A +ILQ ++ Sbjct: 81 GKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAF-GVILQTPKIMRDPDTG 139 Query: 519 GSPGLKSVLSTSRNLSNN----------CDTGEKPVVTFKENIKTREVNRDQGRSFPPKE 568 S G + S + S+ C+ FK++ K R + Sbjct: 140 NSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQN 199 Query: 569 VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIP---IHHPGAFPPLPSRPGFPPPTY-- 623 SQ + ++A P P +S +P + PG+FPP PG PP Sbjct: 200 PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP 259 Query: 624 VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS-----PAGNQVQAGKQSHIPYSQQRPS 678 +PPP +G+ P PG HS P G G S + + P Sbjct: 260 AMPPPPMPPGAAGHG-PPSAGTPGAGHPGHGHSHPHPFPPGGMPHPG-MSQMQLAHHGPH 317 Query: 679 GPGPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-- 734 G G + GP S QPP + P P P P +P G Sbjct: 318 GLGHPHAGPPGSGGQPPPRPP----PGMP---------------HPGPPPMGMPPRGPPF 358 Query: 735 -SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPV 793 SP H G + PP + P G P + P Y + P+ P+ +PPV Sbjct: 359 GSPMGHPGPMP------PHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPV 412 Query: 794 MQQQPL 799 + PL Sbjct: 413 PPRGPL 418 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 50.8 bits (120), Expect = 7e-06 Identities = 89/384 (23%), Positives = 134/384 (34%), Gaps = 46/384 (11%) Query: 626 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 685 PPP M + P T LQ A Q Q +Q + QQ+ + Q Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182 Query: 686 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 745 QQ Q +QQ Q Q QLQ Q QQQQ K HH QQ Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231 Query: 746 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805 QQ +QL Q+Q L + +Q Q Q ++ P QPP+ Q QP + P Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287 Query: 806 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 861 ++ +H P+ +A N+ +Q + + + PG Q P Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344 Query: 862 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSM-----FNEV 907 V + P + + ++ + + + ++ + G + E M F Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT 404 Query: 908 YGKNLTSSSKAEL--SPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSS 965 + SS L P ++SL L +P + P SP PSS Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSP-GQQVQTPQSMPPPPQPSPQPGQPSS 463 Query: 966 LPSSPPTHNHNSVPFSNFGPIGTP 989 P+S + P S+F P +P Sbjct: 464 QPNSNVSSGPAPSP-SSFLPSPSP 486 Score = 36.6 bits (83), Expect = 0.13 Identities = 47/166 (28%), Positives = 63/166 (37%), Gaps = 6/166 (3%) Query: 641 AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGP-GPMNQGPQQS-QPP---SQ 695 A VS P LQ PA G P G G M Q S QPP S Sbjct: 76 ASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSG 135 Query: 696 QPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLW 755 S+ TA +QLQ+Q + QQQ + ++ QQ QQ ++Q Sbjct: 136 MAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSA 195 Query: 756 NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEK 801 Q Q + + ++Q Q Q IKL + Q QQQ L++ Sbjct: 196 MQQQFQAVVQQQQQLQQQQQ-QQQHLIKLHHQNQQQIQQQQQQLQR 240 Score = 31.2 bits (69), Expect = 5.6 Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 15/143 (10%) Query: 652 PTAHSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 710 P++ P G Q A QS +P S P P QQ Q P P P+ Q + Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPML----SSPSP----GQQVQTPQSMPPPPQPSPQPGQPS 462 Query: 711 SQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQVQGPL 764 SQ + SP+ +P+ P P + Q + L NP V P Sbjct: 463 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522 Query: 765 GKIMPVKQPYYLQTQDPIKLFEP 787 G +Q Y + + K EP Sbjct: 523 GSSQAEEQQYLDKLKQLSKYIEP 545 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 50.1 bits (118), Expect = 1e-05 Identities = 58/205 (28%), Positives = 76/205 (37%), Gaps = 30/205 (14%) Query: 566 PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 625 P+ + S T + P S+A PTQ Q P+ PP P P P Sbjct: 505 PQRLPSPTSAPQQPASQAAP------PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA 558 Query: 626 PPPVAFSMGS---------GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYS--- 673 PP A S P G G +P PAG QA + +P + Sbjct: 559 GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP--GPAGPTRQASQAGPVPRTGPP 616 Query: 674 ---QQRPSGPGPMNQ-GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAV 729 Q RPSGPGP + PQ +Q PSQ +P TA + Q + QS T A Sbjct: 617 TTQQPRPSGPGPAGRPKPQLAQKPSQ----DVPPPATAAAGGPPHPQ--LNKSQSLTNAF 670 Query: 730 PALGKSPPHHSGFQQYQQADASKQL 754 +PP S Q +A+ + L Sbjct: 671 NLPEPAPPRPSLSQDEVKAETIRSL 695 Score = 41.2 bits (95), Expect = 0.005 Identities = 56/186 (30%), Positives = 67/186 (36%), Gaps = 37/186 (19%) Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 670 P P R G PP PPP SG PAG +P PT+ +P QA + Sbjct: 472 PGPQRQG--PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTS-APQQPASQAAPPTQG 528 Query: 671 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730 Q RP GP PP+ +P PA P+ Q Q T+Q A P Sbjct: 529 QGRQSRPVAGGP-------GAPPAARP----PASPSPQ--RQAGPPQATRQTSVSGPAPP 575 Query: 731 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQ 790 +PP G QQ Q PP Q P G P +Q P+ P Sbjct: 576 KASGAPP---GGQQRQ---------GPP--QKPPGPAGPTRQ---ASQAGPV----PRTG 614 Query: 791 PPVMQQ 796 PP QQ Sbjct: 615 PPTTQQ 620 Score = 38.5 bits (88), Expect = 0.035 Identities = 48/192 (25%), Positives = 64/192 (33%), Gaps = 37/192 (19%) Query: 663 QAGKQSHIPYSQQRPS--------GPGPMNQGPQQSQ--------------PPSQQPL-- 698 Q +Q P +QQRP GPGP QGP Q PP+ PL Sbjct: 447 QTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506 Query: 699 -----TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQ 753 TS P QP +Q+ Q Q + + P + P S +Q A++Q Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566 Query: 754 LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ---PLEKKMKPFPMEP 810 V GP P Q Q P + P P Q P+ + P +P Sbjct: 567 ----TSVSGPAPPKASGAPPGGQQRQGPPQK-PPGPAGPTRQASQAGPVPRTGPPTTQQP 621 Query: 811 YNHNPSEVKVPE 822 P P+ Sbjct: 622 RPSGPGPAGRPK 633 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 49.7 bits (117), Expect = 2e-05 Identities = 75/327 (22%), Positives = 121/327 (37%), Gaps = 43/327 (13%) Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 670 P+P +PG P + PP ++ PA +Q AG Q +AG Sbjct: 2099 PIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA--------MQNMNPMQAGVQ-RAGLPQQQ 2149 Query: 671 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730 P Q +P G Q Q + + P +Q L+ Q + QQQQ A P Sbjct: 2150 PQQQLQPPMGGMSPQAQQMNMNHNTMP---------SQFRDILRRQQMMQQQQQQG-AGP 2199 Query: 731 ALGKSPPHHSGFQQYQ------QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKL 784 +G +H+ FQQ Q Q Q QG +G+I + Q + ++ Sbjct: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA 2259 Query: 785 FEPSLQPPVMQQQPLEKKMKPFPMEPYNHN-PSEVKVPEFYWDSSYSMADNRSVMAQQAN 843 ++ L QQ + ++P PM P H P++ + P + N+ V + Q Sbjct: 2260 YQQRL-----LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQ-VRSPQPV 2313 Query: 844 IDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN--- 900 R + P P P PRM + S + S ++ + Q + + Sbjct: 2314 PSPRPQSQP----PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQ 2369 Query: 901 NSMFNEVYGK----NLTSSSKAELSPS 923 NSM +++ NL +S +L S Sbjct: 2370 NSMLSQLASNPGMANLHGASATDLGLS 2396 Score = 47.0 bits (110), Expect = 1e-04 Identities = 81/331 (24%), Positives = 117/331 (35%), Gaps = 77/331 (23%) Query: 577 KTPVSEARKTPVT---QTPTQASNSQFIPIH---------HPGAFPPLPSRPGFPPPTYV 624 + PVS+A+ + + +P SQ IH H + P+PSR P T Sbjct: 788 QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT-- 845 Query: 625 IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 684 PP + T PA V P PA + G QS + R + P Sbjct: 846 -PPSIGAQQPPATTIPAPVPTP----------PA---MPPGPQSQALHPPPRQTPTPPTT 891 Query: 685 QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ 744 Q PQQ QP SLPA A S Q Q Q +QQ + + P PP + Sbjct: 892 QLPQQVQP-------SLPA---APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941 Query: 745 YQQADASKQLWNPPQVQGP--LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 802 Q+ NPP + + KQP Q+ +E K Sbjct: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP--------------------SQEVKMEAK 981 Query: 803 MKPFPMEPYNHNP---SEVKVPEFYWDSSYS-------------MADNRSVMAQQANIDR 846 M+ EP + P SE KV + +S+ + D S A Q++ Sbjct: 982 MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSS-PA 1040 Query: 847 RGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 877 G+ +F+PE+ MP ++L + E Sbjct: 1041 PGQSKKKIFKPEELRQALMPTLEALYRQDPE 1071 Score = 42.0 bits (97), Expect = 0.003 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 22/154 (14%) Query: 663 QAGKQSHIPYSQQRPSGPGPMN-QGPQQSQPPSQQPLTSLP--------AQPTAQSTSQL 713 Q G S P + P+G P Q PQ + P P S+P A P +Q + Sbjct: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903 Query: 714 QVQALTQQQQSPTKAVPALGKSPPH--HSGFQQYQQADASKQLWNPPQVQGPLGKIMPVK 771 QV T P A P L PP Q + A+ +Q+ + Q P+ MP Sbjct: 1904 QVTPPTP----PQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959 Query: 772 QPYYLQ-------TQDPIKLFEPSLQPPVMQQQP 798 P T+ P EP + P MQQQP Sbjct: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQP 1993 Score = 41.6 bits (96), Expect = 0.004 Identities = 76/355 (21%), Positives = 116/355 (32%), Gaps = 82/355 (23%) Query: 435 DFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELIL 494 D S Q G RR+ QR I + QC N L Sbjct: 1714 DESNNQQAAATQSPGDSRRLSIQRCIQ-------SLVHACQCRNANCSL----------- 1755 Query: 495 EDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPV---VTFKENI 551 PS K ++Q T + G P K +++ + +C + PV + K+ + Sbjct: 1756 --PSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKL 1813 Query: 552 KTREV-NRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFP 610 + +++ +R Q + + S + +P TPT + Q Sbjct: 1814 RQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQ----------- 1862 Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 670 P+ P P PT P P + P + QA Sbjct: 1863 --PTTPQTPQPTSQPQPT----------------------PPNSMPPYLPRTQAAG---- 1894 Query: 671 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ--ALTQQQQSPTKA 728 P SQ + +G PQ +QPP LP P A +Q+Q A TQ+Q + + Sbjct: 1895 PVSQGKAAGQVTPPTPPQTAQPP-------LPGPPPAAVEMAMQIQRAAETQRQMAHVQI 1947 Query: 729 V--PALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 781 P + PP A + PP +GP G + P P +Q Q P Sbjct: 1948 FQRPIQHQMPP--------MTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP 1994 Score = 33.1 bits (74), Expect = 1.5 Identities = 44/168 (26%), Positives = 58/168 (34%), Gaps = 18/168 (10%) Query: 667 QSHIPYSQQRPSGPGPMNQGPQQSQPPSQ---QPLTSLPAQ-------PTAQSTSQLQV- 715 Q H +Q P PM GP+ QP +Q P T P+Q P A S+ Q V Sbjct: 734 QHHGQLAQPGALNP-PMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS 792 Query: 716 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMP----VK 771 QA P + S H Q Q + +P + P P + Sbjct: 793 QAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQ 852 Query: 772 QPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVK 819 QP T P + P PP Q Q L + P P P +V+ Sbjct: 853 QP--PATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQ 898 Score = 31.6 bits (70), Expect = 4.3 Identities = 35/117 (29%), Positives = 43/117 (36%), Gaps = 12/117 (10%) Query: 658 AGNQVQAGKQSHIPY--SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 715 AGN + Q P Q GP P+ G + P P T P Q S LQ+ Sbjct: 215 AGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQI 274 Query: 716 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQ 772 Q T+ S + A+ K G Q A PQVQ P G + PV Q Sbjct: 275 Q--TKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA-------PQVQQP-GLVTPVAQ 321 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 49.7 bits (117), Expect = 2e-05 Identities = 43/119 (36%), Positives = 49/119 (41%), Gaps = 19/119 (15%) Query: 587 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVP 646 P QTP + P+ PG PP P PG PPP V+PPP+A G P V P Sbjct: 231 PAGQTPPRP------PLGPPG--PPGP--PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280 Query: 647 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 705 G QP P G + G +P P GP P PQQ PP P P P Sbjct: 281 G---QPFGQPPLG-PLPPGPPPPVP-GYGPPPGPPP----PQQGPPPPPGPFPPRPPGP 330 Score = 33.5 bits (75), Expect = 1.1 Identities = 34/138 (24%), Positives = 43/138 (31%), Gaps = 11/138 (7%) Query: 566 PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 625 P + Q L P P P Q P PG FPP P P PP T Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339 Query: 626 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 685 PP + P G P + P P N S P P P ++ Sbjct: 340 PPHLPGP-------PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392 Query: 686 G----PQQSQPPSQQPLT 699 G P + ++ PL+ Sbjct: 393 GDYGPPGREMDTARTPLS 410 >gi|33286444 mastermind-like 2 [Homo sapiens] Length = 1156 Score = 49.7 bits (117), Expect = 2e-05 Identities = 77/343 (22%), Positives = 126/343 (36%), Gaps = 67/343 (19%) Query: 664 AGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQ 723 + +Q QQ+ Q QQ Q PS QP SLP+QP +S LQ + L QQ Q Sbjct: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696 Query: 724 SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPY----YLQTQ 779 + P G+Q QQ Q Q GP P P Y+ +Q Sbjct: 697 N----------QPIAGMGYQVSQQ-QRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745 Query: 780 DPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMA 839 + + + +Q+Q +E+K + + M + +A Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQ--------------------QMLADAEKIA 785 Query: 840 QQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYP 899 Q I+R R P ++ ++ V M +P+ S SS +SL Sbjct: 786 PQDQINRHLSRPPPDYKDQRRNVGNM--------QPTAQYSGGSSTISLNS--------- 828 Query: 900 NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDH----STPAS 955 N ++ N V + + + + LS S + SL + + +LP + + ++ + Sbjct: 829 NQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMN 888 Query: 956 QSPHSSNPSSLPSS--------PPT---HNHNSVPFSNFGPIG 987 Q NP L ++ PPT N+N+V G +G Sbjct: 889 QLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVG 931 Score = 36.2 bits (82), Expect = 0.17 Identities = 73/355 (20%), Positives = 120/355 (33%), Gaps = 62/355 (17%) Query: 497 PSEAKENLILQ-ETSVIESLAADGSPGLKSVLS-TSRNLSNNCDTGEKPVVTFKENIKTR 554 PS E ++++ E S + GSP L+ + + +++N+ + P+ + ++ Sbjct: 355 PSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQP 414 Query: 555 EVNRDQGRSFPP-KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLP 613 + R+ P +EV +L++ + + + Q Q H P + LP Sbjct: 415 QTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQ---------HQPTNWSALP 465 Query: 614 SRPGFPPPTY---VIPPPV--------------AFSMGSG-------YTFPAGVSVPGTF 649 S G P + IP P + GSG Y + AG S G Sbjct: 466 SSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGH 525 Query: 650 LQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQPLTSLPA--- 703 L + ++ + P + R P+ N Q PS P + P+ Sbjct: 526 LDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLH 585 Query: 704 ---QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 760 Q Q Q Q Q QQQQ QQ QQ +Q Q Sbjct: 586 YTQQQQQQQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQQQSSISAQQ 628 Query: 761 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNP 815 Q + +Q Q Q + + Q QQQP + + P +P +P Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 49.7 bits (117), Expect = 2e-05 Identities = 128/544 (23%), Positives = 183/544 (33%), Gaps = 91/544 (16%) Query: 601 IPIHHP-GAFPPLPSRPGFP--PPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP 657 +P P G P P P FP PPTY PP G+ PA + G +P A P Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTY---PPYPSPTGA----PAQPPMLGASSRPGAGQP 2223 Query: 658 AG-NQVQAGKQSHIPYSQQ---RPSGPGPMN----QGPQQSQPPSQQPLTSLPAQPTAQS 709 + G H P + +P P N + P + +PL S P P +S Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP--PFGES 2281 Query: 710 TSQLQVQALTQQQQSPTKAVPALG----KSPPHHSGFQQYQQADASKQLWNP------PQ 759 L+V+ SP+ P LG S H G + + D K P PQ Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341 Query: 760 VQG--------PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM---QQQPLEK----KMK 804 G P + + P + P +P QPP+ Q P E + Sbjct: 2342 SPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPR 2401 Query: 805 PFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQ---ANIDRRGKRSPGVFRPEQDP 861 P +P++ P+ + SS S R + A+ + + R + RP P Sbjct: 2402 SLPSDPFSRVPASPQSQS----SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP 2457 Query: 862 VPRMPFEKSLLEKPSELMSHSSSFL--SLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAE 919 R PF L KP +F SL SL +P L + E Sbjct: 2458 QSRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFP----------AALPAGPAGE 2505 Query: 920 LSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTP-ASQSPHSSNPSSLPSSPPTHNHNSV 978 L + + + GT P+ + P A P P P PP H NS Sbjct: 2506 LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS- 2564 Query: 979 PFSNFGP---IGTPDNRDRRTAD-----RWKTDKPAMGGFGIDY-LSATSSSESSWHQAS 1029 +FGP +G P + + A P+ G G Y LS A Sbjct: 2565 ---HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621 Query: 1030 TPSGTWTGHGPSM-----------EDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQ 1078 S + HG S ED + SL + PG S L Q +++++ Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681 Query: 1079 KQQR 1082 ++QR Sbjct: 2682 QRQR 2685 Score = 48.5 bits (114), Expect = 3e-05 Identities = 79/345 (22%), Positives = 120/345 (34%), Gaps = 35/345 (10%) Query: 494 LEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSN-NCDTGEKPVVTFKENIK 552 L P E+ L+E+ + + SP L++ LS S + E P+ E + Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562 Query: 553 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL 612 T S PP+E ++P+S + P + S P P + PP Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622 Query: 613 PSR--------PGFPPP-TYVIPPPVAFSMGSGYTFPAGVSVP---GTFLQPTAHSPAGN 660 SR P PPP + PP S S + +S P P SP Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682 Query: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720 +A + S P + P+ P P + + PP + L SLP + + + Q + Sbjct: 683 PPEASRLS--PPPEDSPTSPPPED---SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737 Query: 721 QQ---QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNP------------PQVQGPLG 765 + SP P L P Q ++ S Q P PQ +GP Sbjct: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-- 795 Query: 766 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEP 810 + P + +L Q P + P + QP E + P EP Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840 Score = 44.7 bits (104), Expect = 5e-04 Identities = 77/327 (23%), Positives = 118/327 (36%), Gaps = 57/327 (17%) Query: 662 VQAGKQSHIPYSQQRPSGP----GPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQV 715 VQ Q P +++ P P P++ P++S PP + S P + S + Sbjct: 424 VQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL 483 Query: 716 QALTQQQQSPTKAVPALG--KSPPHHSGFQQYQQADASKQLWNPPQ--VQGPLG---KIM 768 ++SP P PP S F +++ S +PP ++ PL + Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543 Query: 769 PVKQPYYLQTQDPIKLFEPSLQPPV---MQQQPLEKKMKPFPME-PYNHNPSEVKVPEFY 824 P+ P+ P P+ PP + P E M P P E P + P ++ + Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603 Query: 825 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 884 +S S S ++ R SP PE P+ P E+S + P E+ S Sbjct: 604 EESPLSPPPEESPLSPPPEASRL---SPP---PEDSPMSPPP-EESPMSPPPEVSRLSPL 656 Query: 885 FLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL 944 + + LSP P+E+ L E +P SP Sbjct: 657 PVV------------------------------SRLSPP--PEESPLSPPPEESPTSPP- 683 Query: 945 PASSDHSTPASQSPHSSNPSSLPSSPP 971 P +S S P SP S P P+SPP Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPP 710 Score = 43.9 bits (102), Expect = 8e-04 Identities = 100/438 (22%), Positives = 141/438 (32%), Gaps = 89/438 (20%) Query: 565 PPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV 624 PP+ ++P+S + T P +AS P P + PP S PP Sbjct: 539 PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598 Query: 625 IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 684 + PP S S P SP +A + S P + P P P Sbjct: 599 LFPPFEESPLS---------------PPPEESPLSPPPEASRLS--PPPEDSPMSPPP-- 639 Query: 685 QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-SPPHHSGFQ 743 + S PP L+ LP + S + ++SPT P + SPP Sbjct: 640 EESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698 Query: 744 QYQQADA------SKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 797 D+ L + P + PL +P+ + L + P + P + + Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPL---LPLPEEPQLCPRSEGPHLSPRPEEPHLSPR 755 Query: 798 PLEKKMKPFPMEPY----NHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPG 853 P E + P EP+ P VPE S + + S ++ ++ SP Sbjct: 756 PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHL------SPQ 809 Query: 854 VFRPEQDPVPRMPF---------------EKSLLEKPSELMSHSSSFLSLTGFSLNQERY 898 P PVP P E L +P E SH S L S E+ Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE--SHLSPELEKPPLSPRPEKP 867 Query: 899 PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL------PASSDHST 952 P E AP+E L+ P PSL PA S+ Sbjct: 868 PE------------------EPGQCPAPEELPLFP----PPGEPSLSPLLGEPALSEPGE 905 Query: 953 PASQSPHSSNPSSLPSSP 970 P P S P LP SP Sbjct: 906 P----PLSPLPEELPLSP 919 Score = 42.4 bits (98), Expect = 0.002 Identities = 61/229 (26%), Positives = 86/229 (37%), Gaps = 23/229 (10%) Query: 786 EPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANID 845 EP L+ P+ ++ PL + P+ P PE S S + + ++ Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486 Query: 846 RRGKRSPGVFRPEQDPV-------PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERY 898 R + SP PE+ P+ P P E+S L P E S S L T S E Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALE-TPLSPPPEAS 543 Query: 899 PNNSMFNEVY----GKNLTSSSKAELSP-SMAPQETSLYSLFEGTPWSPSLPAS------ 947 P + F E + L +S E S S P+E+ + E +P SP AS Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603 Query: 948 --SDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDR 994 S S P +SP S P + SPP + P P+ P R Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652 Score = 33.9 bits (76), Expect = 0.86 Identities = 57/264 (21%), Positives = 96/264 (36%), Gaps = 23/264 (8%) Query: 549 ENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGA 608 E+ T D S PP++ L P+ E+ P+ + P S+ + Sbjct: 694 EDSPTSPPPEDSPASPPPED-----SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748 Query: 609 FPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGT-FLQPTAH----SPAGNQVQ 663 P L RP P ++ P + P +VP L P A SP ++ Sbjct: 749 EPHLSPRPEEP---HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805 Query: 664 AGKQSHIPYSQQRPSGPGPMNQGPQQSQ--PPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 721 Q+ P+ P P ++ P++S P S++P S P + + +L+ L+ + Sbjct: 806 LSPQTEEPHLSPVPEEPC-LSPQPEESHLSPQSEEPCLS-PRPEESHLSPELEKPPLSPR 863 Query: 722 QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 781 + P + P +P F + S L P + + P+ + L Sbjct: 864 PEKPPEE-PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG- 921 Query: 782 IKLFEPSLQPPVMQQQPLEKKMKP 805 EPSL P +M PL + P Sbjct: 922 ----EPSLSPQLMPPDPLPPPLSP 941 Score = 32.7 bits (73), Expect = 1.9 Identities = 51/179 (28%), Positives = 62/179 (34%), Gaps = 20/179 (11%) Query: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720 Q Q +Q + QQ+ Q Q Q QQ L Q Q QLQ Q Q Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962 Query: 721 ----QQQSPTKAVPALGKSPPHHSGFQQYQQADA--------SKQLWNPPQVQGPLGKIM 768 QQQ + + L +S S QQ QQ A Q ++ P GP + Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLT 4022 Query: 769 PVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDS 827 +Q T DP E + P Q PL P E P EVK P DS Sbjct: 4023 GKEQ----NTVDPAVSSEATEGPSTHQGGPLAIGTTP---ESMATEPGEVK-PSLSGDS 4073 Score = 32.0 bits (71), Expect = 3.3 Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 17/128 (13%) Query: 646 PGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP----SQQPLTSL 701 PGT P G Q Q G + G GP QGP + P S P+ Sbjct: 4246 PGTQTSPL-QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG- 4303 Query: 702 PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQ 761 P PT +S Q Q SP+ +P + PP H G + Q P ++ Sbjct: 4304 PVHPTPPPSSP-QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQ----------GPTLE 4352 Query: 762 GPLGKIMP 769 P G++ P Sbjct: 4353 PPPGRVSP 4360 Score = 31.6 bits (70), Expect = 4.3 Identities = 40/164 (24%), Positives = 54/164 (32%), Gaps = 4/164 (2%) Query: 605 HPGAFPPL-PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 663 HPGA P P R + V+ P G G V+ Q H G+ Sbjct: 3814 HPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ-QQQQQHQQQGSMAG 3872 Query: 664 AG--KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 721 +QS + +S Q PM Q Q Q L Q Q Q Q+Q Q Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932 Query: 722 QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLG 765 QQ + + + Q QQ +Q + Q Q +G Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976 Score = 30.8 bits (68), Expect = 7.3 Identities = 61/249 (24%), Positives = 88/249 (35%), Gaps = 36/249 (14%) Query: 567 KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR-PGFPPPTYVI 625 K+ K T L ++ ++ Q Q +S + + P P L ++ PG P + + Sbjct: 3583 KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALS-PSQSPRLLTKLPGQLLPGHGL 3641 Query: 626 PPPVAFSMGSGYTF---PAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGP 682 PP G P G+++PG P ++ Q Q QQ G G Sbjct: 3642 QPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQ----------QQHSGGAGS 3691 Query: 683 MNQGPQQSQPPSQQPLTSLPA-------------QPTAQSTSQLQVQALTQQQQSPTKAV 729 + GP P L SL Q Q +LQ Q QQQQ Sbjct: 3692 L-AGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQ 3750 Query: 730 PALGKSPPHHSGFQQYQQADASKQ-LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS 788 A+ + G Q Q Q L P QG L + + + P Q P + P+ Sbjct: 3751 VAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPP-----QGPQGMLGPA 3805 Query: 789 LQPPVMQQQ 797 Q V+QQQ Sbjct: 3806 -QVAVLQQQ 3813 Score = 30.8 bits (68), Expect = 7.3 Identities = 97/437 (22%), Positives = 148/437 (33%), Gaps = 93/437 (21%) Query: 584 RKTPVTQTP-TQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSG------ 636 R+TP Q P TQ S Q G P GFP P P+ +G+G Sbjct: 4238 RQTPPYQEPGTQTSPLQ-------GLLGCQPQLGGFPGPQ---TGPLQ-ELGAGPRPQGP 4286 Query: 637 --YTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG-PGPMNQGPQQSQPP 693 P G G L P +P + P +RPS P P +Q P ++Q P Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSS---------PQEPKRPSQLPSPSSQLPTEAQLP 4337 Query: 694 SQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQ 753 P T P PT + A Q + T LG P + + + +S Sbjct: 4338 PTHPGTPKPQGPTLEPPPGRVSPAAA--QLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395 Query: 754 LWNPPQVQG---PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPM-- 808 + QV G P + +KQ EP +P + Q ++++ P+ Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQ-------------EPREEPCALGAQSVKREANGEPIGA 4442 Query: 809 -EPYNH--------NPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRR--------GKRS 851 NH + + + + ++ R +A I+ ++ Sbjct: 4443 PGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKL 4502 Query: 852 PGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKN 911 G ++D R P L KP + S +S S + R + +E K Sbjct: 4503 QGTPSNKEDAAARKP----LTPKPKRVQKASDRLVS----SRKKLRKEDGVRASEALLKQ 4554 Query: 912 LTSSSKAELSPSMAPQETSLYSLF---------------EGTPWSPSLPASSDHSTPASQ 956 L + L P P T+ +SLF G S +LP D+ + Sbjct: 4555 L--KQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLT 4612 Query: 957 SPHSSNPSSLPSS-PPT 972 + SNP + PSS PPT Sbjct: 4613 KNNLSNPPTPPSSLPPT 4629 >gi|148277037 AP2 associated kinase 1 [Homo sapiens] Length = 961 Score = 48.9 bits (115), Expect = 3e-05 Identities = 75/279 (26%), Positives = 93/279 (33%), Gaps = 42/279 (15%) Query: 566 PKEVKSQTELRKTPVSEARKT-PVTQTPTQASNSQFIPIHHPGAFPP-LPSRPGFPPP-- 621 P+ VK+ K +AR T P+ T T + Q P LP +P P Sbjct: 334 PEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKR 393 Query: 622 TYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG-- 679 V PPP A + A V P P+ P Q QA + P QQ PS Sbjct: 394 ATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLP---QTQAKQPQAPPTPQQTPSTQA 450 Query: 680 ---PGPMNQGPQQSQP----PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQS--PTKAVP 730 P PQ Q QQ PAQ T Q QA TQQ Q+ P P Sbjct: 451 QGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQP 510 Query: 731 ALGKSPPHHSGFQQ-------YQQADASKQLWNPPQV-----------------QGPLGK 766 A+ + P G Q YQQ +Q Q+ Q P Sbjct: 511 AIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMA 570 Query: 767 IMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805 QP P EP++Q PV QQ ++ P Sbjct: 571 AGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPP 609 Score = 45.1 bits (105), Expect = 4e-04 Identities = 53/214 (24%), Positives = 73/214 (34%), Gaps = 16/214 (7%) Query: 565 PPKEVKSQTELRKTPVSEA-RKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTY 623 PP + QT+ ++ ++TP TQ + +Q P H F + PPP Sbjct: 423 PPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQ 482 Query: 624 VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM 683 P + T P T A P +Q + +Q + QQ Sbjct: 483 QQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQ-------- 534 Query: 684 NQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQ---VQALTQQQQSPTKAVPALGKSPPHHS 740 Q QQ Q QQ T+L Q + LQ A QQ Q A P +P Sbjct: 535 -QQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ--PAPAQEP 591 Query: 741 GFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP 773 Q + Q PP VQG +G + P P Sbjct: 592 AIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSP 625 >gi|73808090 zinc finger protein 207 isoform b [Homo sapiens] Length = 463 Score = 48.9 bits (115), Expect = 3e-05 Identities = 67/291 (23%), Positives = 94/291 (32%), Gaps = 30/291 (10%) Query: 583 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 642 A T P Q P+ PG PP+P PG PP + P V M G Sbjct: 122 AASTSFQPQPVQPQQGYIPPMAQPG-LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180 Query: 643 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPG--PMNQGPQQSQPPSQQPLTS 700 + PG H Q G+ +P P GPG P+ G PP P Sbjct: 181 MP-PGLH-----HQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG----MPPGMPPPVP 230 Query: 701 LPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 760 P P + + + +PT VPA + P F QA A+ V Sbjct: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPA-PQPPVTKPLFPSAGQAQAA--------V 281 Query: 761 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKV 820 QGP+G T +P K P+ P P+ + Sbjct: 282 QGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 341 Query: 821 PE-----FYWDSSYSMADNRSVMAQ-QANIDRRGKRSPGVFRPEQDPVPRM 865 + D S+ + R+ + + Q N+ R G+ G P P+ M Sbjct: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPIGGM 390 Score = 32.3 bits (72), Expect = 2.5 Identities = 47/200 (23%), Positives = 68/200 (34%), Gaps = 28/200 (14%) Query: 598 SQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGV-SVPGTFLQPTAHS 656 + F P++ A P +P FP T + + + A + S P T +A S Sbjct: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 346 Query: 657 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 716 + I ++R P P+ P Q P+ + P P + Q Sbjct: 347 KLIHP-----DEDISLEERRAQLPKYQRNLPR----PGQAPIGNPPVGPIG---GMMPPQ 394 Query: 717 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 776 QQQ +P G+ HH G Y PP QGP P+ PY Sbjct: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM------PPYGQGP-----PMVPPYQG 443 Query: 777 QTQDPIKLFEPSLQPPVMQQ 796 P ++PPVM Q Sbjct: 444 GPPRP----PMGMRPPVMSQ 459 >gi|50345881 cytoplasmic polyadenylation element binding protein 3 [Homo sapiens] Length = 698 Score = 48.5 bits (114), Expect = 3e-05 Identities = 61/293 (20%), Positives = 94/293 (32%), Gaps = 81/293 (27%) Query: 559 DQGRSFPPKEVKSQTELRKTP---VSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615 D+ ++ P + + + + + P VSEA TP++ + + +P P A PP P+ Sbjct: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67 Query: 616 PGF--------------------PPPTYVIPPPVAFSMGSGYTFPAGVS----------- 644 P PPP P + S G T+ G + Sbjct: 68 PDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI 127 Query: 645 --VPGTFL--------QPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPS 694 V GT L P Q+ + H Q+P P P Q Q +QPP Sbjct: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH----HQQPPPPAPAPQPAQPAQPPQ 183 Query: 695 QQP--LTSLPAQPTAQSTSQLQV------QALTQQQQSPTKAVPALGKSPPHHSGFQQYQ 746 QP PA P+ +Q Q + + S + AV A + S + Sbjct: 184 AQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243 Query: 747 QADASKQLWNPPQ-------------------------VQGPLGKIMPVKQPY 774 + W+ P V PL I P+K+P+ Sbjct: 244 THQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296 Score = 32.3 bits (72), Expect = 2.5 Identities = 58/278 (20%), Positives = 97/278 (34%), Gaps = 37/278 (13%) Query: 779 QDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS---EVKVPEFYWDSSYSMADNR 835 QD + + + QP QQQ ++ +P P + PS + P+ +S+ Sbjct: 2 QDDLLMDKSKTQPQPQQQQ--RQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPA 59 Query: 836 SVMAQQANIDRRGKRSPGV------FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLT 889 + D+ SP + P+Q P P+ P PS + S+ + Sbjct: 60 AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119 Query: 890 GFSLNQERYP-NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASS 948 S Q P N +M + + ++ SP + +T + + P +P+ + Sbjct: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQ--QPPPPAPAPQPAQ 177 Query: 949 DHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMG 1008 P +Q P + PS P ++ PI T KP+ Sbjct: 178 PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPI--------------MTSKPSSS 223 Query: 1009 GF--GIDYLSATSSSESSW--HQA-----STPSGTWTG 1037 +A SS+ SSW HQ+ S PS W G Sbjct: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGG 261 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 48.5 bits (114), Expect = 3e-05 Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 7/165 (4%) Query: 602 PIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG---VSVPGT-FLQPTAHSP 657 P+ PG PP P P ++ PP + G FP G V+ PGT L PT Sbjct: 78 PMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIW 137 Query: 658 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQA 717 N+ GK + Y+ + G + Q P+ + AQ AQ+ +Q Q QA Sbjct: 138 VENKTPDGKVYY--YNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195 Query: 718 LTQQQQSPTKAVPALGKSPPHHSGFQQYQ-QADASKQLWNPPQVQ 761 Q Q A ++ Q Q QA A Q Q Q Sbjct: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240 Score = 34.3 bits (77), Expect = 0.66 Identities = 58/294 (19%), Positives = 98/294 (33%), Gaps = 38/294 (12%) Query: 560 QGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP 619 Q ++ +V++Q + + + TP T +P A ++ S P Sbjct: 234 QAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTS-----------TSSSTPSST 282 Query: 620 PPTYVIPPPVAFSMGS----GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSH------ 669 T VA ++ + T + VSV + + +P VQ Q H Sbjct: 283 TSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPP 342 Query: 670 -IPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKA 728 +P+S +P+ P P PP + PL +P Q A Sbjct: 343 AVPHSVPQPTTAIPAF--PPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAA 400 Query: 729 VPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS 788 PA S + +Y+ AD +N ++ K +K+ L+ K+ EP Sbjct: 401 SPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE----KIKEPI 456 Query: 789 LQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQA 842 +P +P PME +P E + E + AQ+A Sbjct: 457 KEP----------SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKA 500 Score = 33.1 bits (74), Expect = 1.5 Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 26/152 (17%) Query: 606 PGAFPPL--PSRPGFPP----------PTYVIPPPVAFSMGSGYTFPAGVSV-------P 646 P PP+ P P PP P + A + S +T P GV V P Sbjct: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175 Query: 647 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQ-QPLTSLPAQP 705 Q + A Q QA Q+ Q + Q Q+Q +Q Q AQ Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235 Query: 706 TAQSTSQLQVQALTQQQ------QSPTKAVPA 731 AQ+ +Q+Q Q Q Q +PT + PA Sbjct: 236 QAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.129 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,179,113 Number of Sequences: 37866 Number of extensions: 2527695 Number of successful extensions: 15107 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 96 Number of HSP's successfully gapped in prelim test: 782 Number of HSP's that attempted gapping in prelim test: 10636 Number of HSP's gapped (non-prelim): 3854 length of query: 1091 length of database: 18,247,518 effective HSP length: 113 effective length of query: 978 effective length of database: 13,968,660 effective search space: 13661349480 effective search space used: 13661349480 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.