Guide to the Human Genome
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Search of human proteins with 41282056

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41282056 pyrin and HIN domain family, member 1 beta 1
isoform [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41282056 pyrin and HIN domain family, member 1 beta 1 isoform...   910   0.0  
gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isofor...   895   0.0  
gi|41282051 pyrin and HIN domain family, member 1 beta 2 isoform...   886   0.0  
gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isofor...   870   0.0  
gi|112789562 interferon, gamma-inducible protein 16 [Homo sapiens]    587   e-167
gi|4505227 myeloid cell nuclear differentiation antigen [Homo sa...   399   e-111
gi|4757734 absent in melanoma 2 [Homo sapiens]                        169   6e-42
gi|169161845 PREDICTED: similar to hCG2041495 [Homo sapiens]          151   1e-36
gi|169162310 PREDICTED: similar to hCG2041495 [Homo sapiens]          150   3e-36
gi|169162679 PREDICTED: hypothetical protein LOC646377 [Homo sap...   150   3e-36
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             44   3e-04
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       43   5e-04
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...    41   0.003
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    41   0.003
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    41   0.003
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    41   0.003
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]             40   0.006
gi|6912458 calcineurin binding protein 1 [Homo sapiens]                38   0.017
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    37   0.029
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  37   0.029
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    37   0.038
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     37   0.049
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    37   0.049
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    37   0.049
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    37   0.049
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    37   0.049
gi|71979937 sialophorin [Homo sapiens]                                 37   0.049
gi|4507181 sialophorin [Homo sapiens]                                  37   0.049
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]             36   0.064
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]             36   0.064

>gi|41282056 pyrin and HIN domain family, member 1 beta 1 isoform
           [Homo sapiens]
          Length = 461

 Score =  910 bits (2352), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA
Sbjct: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
           GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT
Sbjct: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
           PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ
Sbjct: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH
Sbjct: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV
Sbjct: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE
Sbjct: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
           CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ
Sbjct: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420

Query: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK 461
           HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK
Sbjct: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK 461


>gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isoform
           [Homo sapiens]
          Length = 492

 Score =  895 bits (2312), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA
Sbjct: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
           GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT
Sbjct: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
           PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ
Sbjct: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH
Sbjct: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV
Sbjct: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE
Sbjct: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
           CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ
Sbjct: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420

Query: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK 453
           HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK
Sbjct: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK 453


>gi|41282051 pyrin and HIN domain family, member 1 beta 2 isoform
           [Homo sapiens]
          Length = 452

 Score =  886 bits (2289), Expect = 0.0
 Identities = 452/461 (98%), Positives = 452/461 (98%), Gaps = 9/461 (1%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA
Sbjct: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
           GLGKLIEFFKEIPTLGDLAETLKREKLKV         KGIIPSKKTKQKEVYPATPACT
Sbjct: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKV---------KGIIPSKKTKQKEVYPATPACT 111

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
           PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ
Sbjct: 112 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 171

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH
Sbjct: 172 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 231

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV
Sbjct: 232 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 291

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE
Sbjct: 292 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 351

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
           CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ
Sbjct: 352 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 411

Query: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK 461
           HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK
Sbjct: 412 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK 452


>gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isoform
           [Homo sapiens]
          Length = 483

 Score =  870 bits (2249), Expect = 0.0
 Identities = 444/453 (98%), Positives = 444/453 (98%), Gaps = 9/453 (1%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA
Sbjct: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
           GLGKLIEFFKEIPTLGDLAETLKREKLKV         KGIIPSKKTKQKEVYPATPACT
Sbjct: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKV---------KGIIPSKKTKQKEVYPATPACT 111

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
           PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ
Sbjct: 112 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 171

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH
Sbjct: 172 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 231

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV
Sbjct: 232 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 291

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE
Sbjct: 292 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 351

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
           CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ
Sbjct: 352 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 411

Query: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK 453
           HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK
Sbjct: 412 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK 444


>gi|112789562 interferon, gamma-inducible protein 16 [Homo sapiens]
          Length = 729

 Score =  587 bits (1512), Expect = e-167
 Identities = 308/457 (67%), Positives = 363/457 (79%), Gaps = 10/457 (2%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           M   YK IVLLKGLEVINDYHFR+VKSLLSNDLKLN KM+EEYDKIQIADLMEEKF GDA
Sbjct: 1   MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
           GLGKLI+ F++IPTL DLAETLK+EKLKV         KG   S+K K KEV   +PA +
Sbjct: 61  GLGKLIKIFEDIPTLEDLAETLKKEKLKV---------KGPALSRKRK-KEVDATSPAPS 110

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
            S+ +  +GAE T G QKRKK ++E+ G K SK+S+EQT+P   AGA  STAMGRSP P+
Sbjct: 111 TSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPK 170

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           TS SAPPN+SSTE+ K +A    T  +N+ ++ P+I  VL+ TK F+YE+ E E++ MFH
Sbjct: 171 TSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFH 230

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVATQTQFFHVKVLN +LK KF  K+IIIIS+Y + +SLLEVNE S+VSEAGP+QTFEV
Sbjct: 231 ATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEV 290

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           P  II RAK+  KI+ILHKQ SG IVYG+FMLH K VN+KTTIYEIQD  G M VVG G+
Sbjct: 291 PNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQ 350

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
           CHNIPCE+GDKL+LFCFRLRK+  MSKL+SEMHSFIQI+K TN R++D +SM LPQEQ Q
Sbjct: 351 CHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQ 410

Query: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKD 457
            P PSEASTT PESHL+TPQMPPTTPSSS FTK ++D
Sbjct: 411 LPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSED 447



 Score =  177 bits (449), Expect = 2e-44
 Identities = 118/298 (39%), Positives = 154/298 (51%), Gaps = 21/298 (7%)

Query: 114 PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 173
           P  P  TPS+    K +E+T+                R ++ KE +        S   A 
Sbjct: 429 PQMPPTTPSSSFFTKKSEDTISKMN---------DFMRMQILKEGSHFPGPFMTSIGPAE 479

Query: 174 GRSPPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIA-----MVLNATKVFKY 228
                PQ     PP+T S+  L  L  R  T  + +  ED   +     MVLNAT+ F Y
Sbjct: 480 SHPHTPQM----PPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY 535

Query: 229 ESSENEQRRMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASS 288
           E  E  Q++MFHATVAT+ + F VKV NI+LK KF  K+II I+NY  RN  LEV   + 
Sbjct: 536 EPKE--QKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593

Query: 289 VSEAGPDQTFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQD 348
           V++   D+  E+PK +IR A   PKIN L  QT G  V G+F +H K V  + T YEIQD
Sbjct: 594 VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQD 653

Query: 349 KTGSMAVVGKGECHNIPCEKGDKLRLFCFRLR-KRENMSKLMSEMHSFIQIQKNTNQR 405
            TG M VV  G    I CE+GDKL+L CF L  K  N  +L S +HS I++ K    +
Sbjct: 654 NTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNK 711


>gi|4505227 myeloid cell nuclear differentiation antigen [Homo
           sapiens]
          Length = 407

 Score =  399 bits (1024), Expect = e-111
 Identities = 214/400 (53%), Positives = 282/400 (70%), Gaps = 5/400 (1%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           M N YKKI+LLKG E+++DYHF  +KSLL+ DL L  KM+EEY++I+I DLME+KF G A
Sbjct: 1   MVNEYKKILLLKGFELMDDYHFTSIKSLLAYDLGLTTKMQEEYNRIKITDLMEKKFQGVA 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
            L KLIE  K++P+L +L   L++EK KVA KI++   +   P KK  Q+EV  A PA T
Sbjct: 61  CLDKLIELAKDMPSLKNLVNNLRKEKSKVAKKIKT---QEKAPVKKINQEEVGLAAPAPT 117

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
             N+LT++        QKRK P++E+T  KR+K+S+EQ++P   +GASTS A+   P PQ
Sbjct: 118 ARNKLTSEARGRIPVAQKRKTPNKEKTEAKRNKVSQEQSKPPGPSGASTSAAVDHPPLPQ 177

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           TSSS P NTS T + +  A R   A +N+ + DP+  +VL AT  FKYES EN +  MFH
Sbjct: 178 TSSSTPSNTSFTPNQETQAQRQVDARRNVPQNDPVTVVVLKATAPFKYESPENGKSTMFH 237

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVA++TQ+FHVKV +INLK KF++K++I IS+YS+   ++E+ EASSVS+   +Q FEV
Sbjct: 238 ATVASKTQYFHVKVFDINLKEKFVRKKVITISDYSECKGVMEIKEASSVSDF--NQNFEV 295

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           P  II  A K PKI+ L+KQ SG +VYGLFML  K V++K TIYEIQD TGSM VVG G+
Sbjct: 296 PNRIIEIANKTPKISQLYKQASGTMVYGLFMLQKKSVHKKNTIYEIQDNTGSMDVVGSGK 355

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQK 400
            HNI CEKGDKLRLFC +LR  +   KL+   HSFI++ K
Sbjct: 356 WHNIKCEKGDKLRLFCLQLRTVDRKLKLVCGSHSFIKVIK 395



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 3/70 (4%)

Query: 386 SKLMSEMHSFIQI---QKNTNQRSHDSRSMALPQEQSQHPKPSEASTTLPESHLKTPQMP 442
           +KL SE    I +   +K  N+   +++   + QEQS+ P PS AST+    H   PQ  
Sbjct: 120 NKLTSEARGRIPVAQKRKTPNKEKTEAKRNKVSQEQSKPPGPSGASTSAAVDHPPLPQTS 179

Query: 443 PTTPSSSSFT 452
            +TPS++SFT
Sbjct: 180 SSTPSNTSFT 189


>gi|4757734 absent in melanoma 2 [Homo sapiens]
          Length = 343

 Score =  169 bits (427), Expect = 6e-42
 Identities = 125/400 (31%), Positives = 189/400 (47%), Gaps = 62/400 (15%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           M + YK+I+LL GL+ I D      K  LS++  +        ++IQ+A LM +     +
Sbjct: 1   MESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLHTANRIQVATLMIQNAGAVS 60

Query: 61  GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
            + K I  F+++  +                                             
Sbjct: 61  AVMKTIRIFQKLNYM--------------------------------------------- 75

Query: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
               L AK  +E    +K K   + ++ TK   +S+ +  P+ SA      A  R+ P  
Sbjct: 76  ----LLAKRLQE----EKEKVDKQYKSVTKPKPLSQAEMSPAASAAIRNDVAKQRAAPKV 127

Query: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
           +    P      E  + +A + +   +  F++  +  MVL A K F +E+ E +Q  MFH
Sbjct: 128 SPHVKP------EQKQMVAQQESI--REGFQKRCLPVMVLKAKKPFTFETQEGKQE-MFH 178

Query: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
           ATVAT+ +FF VKV N  LK KFI KRIIII+ Y + +  LEVN AS V +A  DQ   V
Sbjct: 179 ATVATEKEFFFVKVFNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNV 238

Query: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
           P +IIR+A + PKIN L  Q  G IV GLF++      +K  ++++ D TG M V+G   
Sbjct: 239 PLNIIRKAGETPKINTLQTQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRN 298

Query: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQK 400
              + C++GDK+RL  F L K     +L S +HS I++ K
Sbjct: 299 EDTMKCKEGDKVRLTFFTLSKNGEKLQLTSGVHSTIKVIK 338


>gi|169161845 PREDICTED: similar to hCG2041495 [Homo sapiens]
          Length = 196

 Score =  151 bits (382), Expect = 1e-36
 Identities = 87/156 (55%), Positives = 100/156 (64%), Gaps = 14/156 (8%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           M + YK  VLLKGLE INDYHF I+ SLL NDLKLN   ++EYDKIQIADLMEEKFPGDA
Sbjct: 41  MVSKYKNNVLLKGLEAINDYHFSIINSLLINDLKLNSTRRDEYDKIQIADLMEEKFPGDA 100

Query: 61  GLGKLIEFFKEIPT-LGDLAETLKREK-------------LKVANKIESIPVKGIIPSKK 106
           GLGKL    +   T  GDLAETL++ K             L V NKI+SIP KG   SKK
Sbjct: 101 GLGKLRTLQRNTNTGRGDLAETLRKVKRSSALGLDVLLFSLLVVNKIKSIPAKGKTSSKK 160

Query: 107 TKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKP 142
            KQ++V P TP  T   + TA+G EET   Q+   P
Sbjct: 161 RKQRKVGPTTPLATTDKKFTAEGGEETPIAQRFHTP 196


>gi|169162310 PREDICTED: similar to hCG2041495 [Homo sapiens]
          Length = 196

 Score =  150 bits (378), Expect = 3e-36
 Identities = 86/156 (55%), Positives = 99/156 (63%), Gaps = 14/156 (8%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           M + YK  VLLKGLE INDYHF I+ SLL NDLKLN   ++EYDKIQIADLMEEKFPGDA
Sbjct: 41  MVSKYKNNVLLKGLEAINDYHFSIINSLLINDLKLNSTRRDEYDKIQIADLMEEKFPGDA 100

Query: 61  GLGKLIEFFKEIPT-LGDLAETLKREK-------------LKVANKIESIPVKGIIPSKK 106
           G GKL    +   T  GDLAETL++ K             L V NKI+SIP KG   SKK
Sbjct: 101 GFGKLRTLQRNTNTGRGDLAETLRKVKRSSALGLDVLLFSLLVVNKIKSIPAKGKTSSKK 160

Query: 107 TKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKP 142
            KQ++V P TP  T   + TA+G EET   Q+   P
Sbjct: 161 RKQRKVGPTTPLATTDKKFTAEGGEETPIAQRFHTP 196


>gi|169162679 PREDICTED: hypothetical protein LOC646377 [Homo
           sapiens]
          Length = 196

 Score =  150 bits (378), Expect = 3e-36
 Identities = 86/156 (55%), Positives = 99/156 (63%), Gaps = 14/156 (8%)

Query: 1   MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
           M + YK  VLLKGLE INDYHF I+ SLL NDLKLN   ++EYDKIQIADLMEEKFPGDA
Sbjct: 41  MVSKYKNNVLLKGLEAINDYHFSIINSLLINDLKLNSTRRDEYDKIQIADLMEEKFPGDA 100

Query: 61  GLGKLIEFFKEIPT-LGDLAETLKREK-------------LKVANKIESIPVKGIIPSKK 106
           G GKL    +   T  GDLAETL++ K             L V NKI+SIP KG   SKK
Sbjct: 101 GFGKLRTLQRNTNTGRGDLAETLRKVKRSSALGLDVLLFSLLVVNKIKSIPAKGKTSSKK 160

Query: 107 TKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKP 142
            KQ++V P TP  T   + TA+G EET   Q+   P
Sbjct: 161 RKQRKVGPTTPLATTDKKFTAEGGEETPIAQRFHTP 196


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 1/89 (1%)

Query: 73   PTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEE 132
            P L D+ E  ++ K K   K E +  K ++  +KT++K++ P  P   P   +  +    
Sbjct: 1019 PVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPP 1078

Query: 133  TLGPQKRKKPSEEETGTKRSKMSKEQTRP 161
             + P+  K PS  ET T   K S++  +P
Sbjct: 1079 PIQPEAEKFPS-TETATLAQKPSQDTEKP 1106


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/73 (35%), Positives = 32/73 (43%)

Query: 134  LGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTE 193
            L P++   P+  +  T      K    P CSA A+ ST    SPPP      PP      
Sbjct: 1218 LQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLS 1277

Query: 194  SLKPLANRHATAS 206
            SLKP A   ATA+
Sbjct: 1278 SLKPAAPSPATAA 1290


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
           sapiens]
          Length = 817

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 91  NKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETG-T 149
           NK       G++P+   K+  V  A P+  PS  +  K   +   P+KR  PS+  +   
Sbjct: 472 NKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 531

Query: 150 KRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLANRHATA 205
            RS     QT    +  A+ ++    S  P T     P    TE  KP   +  TA
Sbjct: 532 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG-KPAEVKKMTA 586


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 91  NKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETG-T 149
           NK       G++P+   K+  V  A P+  PS  +  K   +   P+KR  PS+  +   
Sbjct: 737 NKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 796

Query: 150 KRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLANRHATA 205
            RS     QT    +  A+ ++    S  P T     P    TE  KP   +  TA
Sbjct: 797 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG-KPAEVKKMTA 851


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 91  NKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETG-T 149
           NK       G++P+   K+  V  A P+  PS  +  K   +   P+KR  PS+  +   
Sbjct: 472 NKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 531

Query: 150 KRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLANRHATA 205
            RS     QT    +  A+ ++    S  P T     P    TE  KP   +  TA
Sbjct: 532 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG-KPAEVKKMTA 586


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 91  NKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETG-T 149
           NK       G++P+   K+  V  A P+  PS  +  K   +   P+KR  PS+  +   
Sbjct: 737 NKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 796

Query: 150 KRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLANRHATA 205
            RS     QT    +  A+ ++    S  P T     P    TE  KP   +  TA
Sbjct: 797 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG-KPAEVKKMTA 851


>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
          Length = 360

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 7/85 (8%)

Query: 127 AKGAEETLGPQKRKKPSEEETG---TKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSS 183
           A+GA   +G +KR +      G    KR K S++ T  +CSA    ST+ GR       +
Sbjct: 120 ARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSA----STSQGRKASTAPGA 175

Query: 184 SAPPNTSSTESLKPLANRHATASKN 208
            A P+   TE  K  A R   +S +
Sbjct: 176 EASPSPCITERSKQKARRRTRSSSS 200



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 104 SKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSC 163
           S+K K+K     +  C+ S   T++G + +  P     PS   T   + K ++ +TR S 
Sbjct: 144 SEKRKKKSRKDTSRNCSAS---TSQGRKASTAPGAEASPSPCITERSKQK-ARRRTRSSS 199

Query: 164 SAGASTSTAMGRSPPPQTSSSA 185
           S+ +S+S++   S    +SSS+
Sbjct: 200 SSSSSSSSSSSSSSSSSSSSSS 221


>gi|6912458 calcineurin binding protein 1 [Homo sapiens]
          Length = 2220

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 1/87 (1%)

Query: 114  PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 173
            PA P C P+      GAE T   + + +P     G  +   S+ Q   S    AS+    
Sbjct: 2046 PAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPS 2105

Query: 174  GRSPPPQTSSSAPPNTSSTESLKPLAN 200
              S  P       P  S  +S +PL N
Sbjct: 2106 SGSAQPPEGHPGKPEPSRAKS-RPLPN 2131


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 8/144 (5%)

Query: 63  GKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPS 122
           G+   F  E  T      T   E+  +AN+  ++   G   +++    E     PA    
Sbjct: 745 GQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTE 804

Query: 123 NRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTS 182
           NR      E T        P++      R+ ++ E+T PS +           +    TS
Sbjct: 805 NR------ERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTS 858

Query: 183 SSAPPNTSSTESLKPLANRHATAS 206
           SSA P   +  +  PLAN + T+S
Sbjct: 859 SSAEPTEHAERT--PLANENTTSS 880



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 48/205 (23%), Positives = 80/205 (39%), Gaps = 37/205 (18%)

Query: 120 TPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPP 179
           TPS     +  E T   +    P+E      R+ ++ E+T PS +           +   
Sbjct: 596 TPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEK 655

Query: 180 QTSSSAPP----------NTSSTES-LKPLANRHATASKNIFRE--DPIIAMVLNA---T 223
            TSSSA P          N ++T S  +P  NR  TA++N       P     + A   T
Sbjct: 656 TTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKT 715

Query: 224 KVFKYESSENEQRRMFHATVAT---------QTQFFHVKVLNINLKRKFIKKRIIIISNY 274
            +F  E +EN +R     T ++         +T F + K  + + +           + +
Sbjct: 716 TLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEP----------TEH 765

Query: 275 SKRNSLLEVNEASSVSEAGPDQTFE 299
            +R  L   NE +++S AGP +  E
Sbjct: 766 GERTPL--ANENTTLSPAGPTENRE 788



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 29/124 (23%), Positives = 43/124 (34%), Gaps = 19/124 (15%)

Query: 334 TKIVNRKTTIYEIQDKTGSMAVVGKGECHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMH 393
           +KI  RK+T       TG   V  K +    P EK                + K  +  H
Sbjct: 226 SKINCRKST-------TGKSTVTRKSDKTGRPLEKS------------MSTLDKTSTSSH 266

Query: 394 SFIQIQKNTNQRSHDSRSMALPQEQSQHPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK 453
                  N+       +S + P++ +   K +  +T  PE   KT     T  S    TK
Sbjct: 267 KTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTK 326

Query: 454 VTKD 457
            TK+
Sbjct: 327 TTKN 330


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 12/113 (10%)

Query: 74   TLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEET 133
            T GDL +   ++++K  N   +  + G  P   +K     P   + TPSN   +K     
Sbjct: 959  TTGDLGKEKTQKRVKEGNGTSNSTLSG--PGLDSK-----PGKRSRTPSNDGKSKDK--- 1008

Query: 134  LGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAP 186
              P KRKK   E      S  ++  T P+ + G+ +  + GRS  P   ++ P
Sbjct: 1009 --PPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPP 1059


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 8/144 (5%)

Query: 63  GKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPS 122
           G+   F  E  T      T   E+  +AN+  ++      P++ T+ +E   A    TP 
Sbjct: 683 GQRTPFANEKTTSSSAEPTEHGERTPLANENTTLS-----PAEPTENRE-RTANEKTTPF 736

Query: 123 NRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTS 182
                +  E T        P++      R+ ++ E+T PS +           +    TS
Sbjct: 737 PAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTS 796

Query: 183 SSAPPNTSSTESLKPLANRHATAS 206
           SSA P   +  +  PLAN + T+S
Sbjct: 797 SSAEPTEHAERT--PLANENTTSS 818



 Score = 35.8 bits (81), Expect = 0.084
 Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 120 TPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPP 179
           TPS     +  E T   +    P+E      R+ ++ E+T PS +           +   
Sbjct: 534 TPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEK 593

Query: 180 QTSSSAPPNTSSTESLKPLANRHATAS 206
            TSSSA P  +  E   PLAN + T S
Sbjct: 594 TTSSSAEP--TEHEERTPLANENTTPS 618



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 25/119 (21%), Positives = 51/119 (42%), Gaps = 2/119 (1%)

Query: 81   TLKREKLKVANKIESIPVKGIIPSKKTK--QKEVYPATPACTPSNRLTAKGAEETLGPQK 138
            T  R++   AN I   P + I  +K+T    +++   T   T     T    E+T    +
Sbjct: 1126 TEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPE 1185

Query: 139  RKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKP 197
            +     E+T   + K +    +P+ + G +T T      P +++ +     + T+++KP
Sbjct: 1186 KPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTIKP 1244



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 29/124 (23%), Positives = 43/124 (34%), Gaps = 19/124 (15%)

Query: 334 TKIVNRKTTIYEIQDKTGSMAVVGKGECHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMH 393
           +KI  RK+T       TG   V  K +    P EK                + K  +  H
Sbjct: 164 SKINCRKST-------TGKSTVTRKSDKTGRPLEKS------------MSTLDKTSTSSH 204

Query: 394 SFIQIQKNTNQRSHDSRSMALPQEQSQHPKPSEASTTLPESHLKTPQMPPTTPSSSSFTK 453
                  N+       +S + P++ +   K +  +T  PE   KT     T  S    TK
Sbjct: 205 KTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTK 264

Query: 454 VTKD 457
            TK+
Sbjct: 265 TTKN 268


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 15/117 (12%)

Query: 70   KEIPTLGDLAETLK-REKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAK 128
            KE P   ++ E  K +EK +VA K E    K   PSK  ++KE  P             K
Sbjct: 908  KEAPAKVEVKEDAKPKEKTEVAKK-EPDDAKAKEPSKPAEKKEAAP-----------EKK 955

Query: 129  GAEETLGPQKRKKPSEEETGTKRSK-MSKEQTRPSC-SAGASTSTAMGRSPPPQTSS 183
              +E    +  +KP  E    +  K +SKE ++P    A  S+ST    S PP+ ++
Sbjct: 956  DTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKAT 1012



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 10/119 (8%)

Query: 79  AETLKREKLKVANKIESIPVKGIIPSK-KTKQKEVYPATPACTPSNRLTAKGAEETLGPQ 137
           A++ ++E+ K   +++S       P K K+  KE   + P      +  AK   E   P+
Sbjct: 530 AKSPEKEEAKSPAEVKS-------PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582

Query: 138 KRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLK 196
           K K P++EE  +     S E+ +      A  S A  +SP  + + S P    S E  K
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK-SPAEAKSPVKEEAKS-PAEVKSPEKAK 639



 Score = 32.3 bits (72), Expect = 0.93
 Identities = 30/120 (25%), Positives = 42/120 (35%), Gaps = 2/120 (1%)

Query: 79  AETLKREKLKVANKIES-IPVKGIIPSK-KTKQKEVYPATPACTPSNRLTAKGAEETLGP 136
           AE    EK K   K E+  P +   P K K+  KE   +        +  AK   E   P
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635

Query: 137 QKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLK 196
           +K K P++EE  +     S E+        A +        P +  S       S E  K
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)

Query: 114 PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 173
           PA  A +P     +   EE   P + K P +EE  +     S E+ +      A  S   
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPPE 563

Query: 174 GRSPPPQTSSSAPPNTSSTESLKPLANRHA 203
            +SP  + + S P    S E  K  A   A
Sbjct: 564 AKSPEKEEAKS-PAEVKSPEKAKSPAKEEA 592



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 39/158 (24%), Positives = 55/158 (34%), Gaps = 12/158 (7%)

Query: 79  AETLKREKLKVANKIES-IPVKGIIPSK---KTKQKEVYPATPACTPSNRLTAKGAEETL 134
           AE    EK K   K E+  P K   P K   K+ +K   P         +  +   EE  
Sbjct: 672 AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 731

Query: 135 GPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM---GRSP----PPQTSSSAPP 187
            P+K K P +EE  +     S E+ +          T      RSP    P +  S    
Sbjct: 732 TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE 791

Query: 188 NTSSTESLK-PLANRHATASKNIFREDPIIAMVLNATK 224
              S E  K PL        K I +++ + + V    K
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 10/80 (12%)

Query: 84   REKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT----------PSNRLTAKGAEET 133
            +E  K A K E+ P K     +K K+ E  P T A            PS     K  + +
Sbjct: 939  KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998

Query: 134  LGPQKRKKPSEEETGTKRSK 153
               QK  KP E+ T  K +K
Sbjct: 999  STDQKDSKPPEKATEDKAAK 1018



 Score = 29.6 bits (65), Expect = 6.0
 Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 4/96 (4%)

Query: 103 PSKKTKQ--KEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTR 160
           P K+ K   KE   +        +  AK   E   P+K K P++EE   K    +K   +
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE--AKSPPEAKSPEK 569

Query: 161 PSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLK 196
               + A   +      P +  + +P    S E  K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 84  REKLKVANKIESIPVKGIIPSKKTKQKEVYPATPA---CTPSNRLTAKGAEETLGPQKRK 140
           R ++K + KI  +      P+K T  K   PA P       S     K  E++    +  
Sbjct: 288 RSQVKASEKILQVRAASA-PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346

Query: 141 KPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLAN 200
             SEEET   ++ +  + +  +   GA+++ A  +  P + ++ APP  +     K  A 
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPA--KESPRKGAAPAPPGKTGPAVAKAQAG 404

Query: 201 RHATASKNIFRE 212
           +    S++   E
Sbjct: 405 KREEDSQSSSEE 416



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 9/92 (9%)

Query: 97  PVKGIIPSKKTKQKEVYPATPACTPS-NRLTAKGAEETLGPQKRKKPSEEETGTKRSKMS 155
           P K   P +  +   V    PA  PS  +  A  A+   GP++    SEEE+ ++    +
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883

Query: 156 KEQTRPS--------CSAGASTSTAMGRSPPP 179
             Q +PS          A A  S   G +P P
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 15/144 (10%)

Query: 85  EKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSE 144
           ++  V  K    P +    S  TK+     A PA      +T +     L P KR K  E
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE 267

Query: 145 EETGTKRSKMSKEQTRPSCSAG----------ASTSTAMGRSPPPQTSSSAPPN-----T 189
           EE+ +       E+  P+ +               ++A  +  P + ++ APP       
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVA 327

Query: 190 SSTESLKPLANRHATASKNIFRED 213
           S T++ KP  +  +++ ++   E+
Sbjct: 328 SQTKAGKPEEDSESSSEESSDSEE 351



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 11/124 (8%)

Query: 103 PSKKTKQKEVYPATPACTPSNRLTAKGA--EETLGPQKRKKPSEEETGTKRSKMSKEQTR 160
           P+K++ +K   PA P  T      A+    EE       +  SEEE   +     K    
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436

Query: 161 PSCSAGASTSTAMGRSPPP---------QTSSSAPPNTSSTESLKPLANRHATASKNIFR 211
            + SA A  S   G +P P         Q         S + S +  ++R A A+ N  +
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496

Query: 212 EDPI 215
             P+
Sbjct: 497 VKPL 500


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 84  REKLKVANKIESIPVKGIIPSKKTKQKEVYPATPA---CTPSNRLTAKGAEETLGPQKRK 140
           R ++K + KI  +      P+K T  K   PA P       S     K  E++    +  
Sbjct: 288 RSQVKASEKILQVRAASA-PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346

Query: 141 KPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLAN 200
             SEEET   ++ +  + +  +   GA+++ A  +  P + ++ APP  +     K  A 
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPA--KESPRKGAAPAPPGKTGPAVAKAQAG 404

Query: 201 RHATASKNIFRE 212
           +    S++   E
Sbjct: 405 KREEDSQSSSEE 416



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 9/92 (9%)

Query: 97  PVKGIIPSKKTKQKEVYPATPACTPS-NRLTAKGAEETLGPQKRKKPSEEETGTKRSKMS 155
           P K   P +  +   V    PA  PS  +  A  A+   GP++    SEEE+ ++    +
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883

Query: 156 KEQTRPS--------CSAGASTSTAMGRSPPP 179
             Q +PS          A A  S   G +P P
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 15/144 (10%)

Query: 85  EKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSE 144
           ++  V  K    P +    S  TK+     A PA      +T +     L P KR K  E
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE 267

Query: 145 EETGTKRSKMSKEQTRPSCSAG----------ASTSTAMGRSPPPQTSSSAPPN-----T 189
           EE+ +       E+  P+ +               ++A  +  P + ++ APP       
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVA 327

Query: 190 SSTESLKPLANRHATASKNIFRED 213
           S T++ KP  +  +++ ++   E+
Sbjct: 328 SQTKAGKPEEDSESSSEESSDSEE 351



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 11/124 (8%)

Query: 103 PSKKTKQKEVYPATPACTPSNRLTAKGA--EETLGPQKRKKPSEEETGTKRSKMSKEQTR 160
           P+K++ +K   PA P  T      A+    EE       +  SEEE   +     K    
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436

Query: 161 PSCSAGASTSTAMGRSPPP---------QTSSSAPPNTSSTESLKPLANRHATASKNIFR 211
            + SA A  S   G +P P         Q         S + S +  ++R A A+ N  +
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496

Query: 212 EDPI 215
             P+
Sbjct: 497 VKPL 500


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 84  REKLKVANKIESIPVKGIIPSKKTKQKEVYPATPA---CTPSNRLTAKGAEETLGPQKRK 140
           R ++K + KI  +      P+K T  K   PA P       S     K  E++    +  
Sbjct: 288 RSQVKASEKILQVRAASA-PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346

Query: 141 KPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLAN 200
             SEEET   ++ +  + +  +   GA+++ A  +  P + ++ APP  +     K  A 
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPA--KESPRKGAAPAPPGKTGPAVAKAQAG 404

Query: 201 RHATASKNIFRE 212
           +    S++   E
Sbjct: 405 KREEDSQSSSEE 416



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 9/92 (9%)

Query: 97  PVKGIIPSKKTKQKEVYPATPACTPS-NRLTAKGAEETLGPQKRKKPSEEETGTKRSKMS 155
           P K   P +  +   V    PA  PS  +  A  A+   GP++    SEEE+ ++    +
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883

Query: 156 KEQTRPS--------CSAGASTSTAMGRSPPP 179
             Q +PS          A A  S   G +P P
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 15/144 (10%)

Query: 85  EKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSE 144
           ++  V  K    P +    S  TK+     A PA      +T +     L P KR K  E
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE 267

Query: 145 EETGTKRSKMSKEQTRPSCSAG----------ASTSTAMGRSPPPQTSSSAPPN-----T 189
           EE+ +       E+  P+ +               ++A  +  P + ++ APP       
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVA 327

Query: 190 SSTESLKPLANRHATASKNIFRED 213
           S T++ KP  +  +++ ++   E+
Sbjct: 328 SQTKAGKPEEDSESSSEESSDSEE 351



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 11/124 (8%)

Query: 103 PSKKTKQKEVYPATPACTPSNRLTAKGA--EETLGPQKRKKPSEEETGTKRSKMSKEQTR 160
           P+K++ +K   PA P  T      A+    EE       +  SEEE   +     K    
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436

Query: 161 PSCSAGASTSTAMGRSPPP---------QTSSSAPPNTSSTESLKPLANRHATASKNIFR 211
            + SA A  S   G +P P         Q         S + S +  ++R A A+ N  +
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496

Query: 212 EDPI 215
             P+
Sbjct: 497 VKPL 500


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 84  REKLKVANKIESIPVKGIIPSKKTKQKEVYPATPA---CTPSNRLTAKGAEETLGPQKRK 140
           R ++K + KI  +      P+K T  K   PA P       S     K  E++    +  
Sbjct: 288 RSQVKASEKILQVRAASA-PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346

Query: 141 KPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNTSSTESLKPLAN 200
             SEEET   ++ +  + +  +   GA+++ A  +  P + ++ APP  +     K  A 
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPA--KESPRKGAAPAPPGKTGPAVAKAQAG 404

Query: 201 RHATASKNIFRE 212
           +    S++   E
Sbjct: 405 KREEDSQSSSEE 416



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 9/92 (9%)

Query: 97  PVKGIIPSKKTKQKEVYPATPACTPS-NRLTAKGAEETLGPQKRKKPSEEETGTKRSKMS 155
           P K   P +  +   V    PA  PS  +  A  A+   GP++    SEEE+ ++    +
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883

Query: 156 KEQTRPS--------CSAGASTSTAMGRSPPP 179
             Q +PS          A A  S   G +P P
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 15/144 (10%)

Query: 85  EKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSE 144
           ++  V  K    P +    S  TK+     A PA      +T +     L P KR K  E
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE 267

Query: 145 EETGTKRSKMSKEQTRPSCSAG----------ASTSTAMGRSPPPQTSSSAPPN-----T 189
           EE+ +       E+  P+ +               ++A  +  P + ++ APP       
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVA 327

Query: 190 SSTESLKPLANRHATASKNIFRED 213
           S T++ KP  +  +++ ++   E+
Sbjct: 328 SQTKAGKPEEDSESSSEESSDSEE 351



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 11/124 (8%)

Query: 103 PSKKTKQKEVYPATPACTPSNRLTAKGA--EETLGPQKRKKPSEEETGTKRSKMSKEQTR 160
           P+K++ +K   PA P  T      A+    EE       +  SEEE   +     K    
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436

Query: 161 PSCSAGASTSTAMGRSPPP---------QTSSSAPPNTSSTESLKPLANRHATASKNIFR 211
            + SA A  S   G +P P         Q         S + S +  ++R A A+ N  +
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496

Query: 212 EDPI 215
             P+
Sbjct: 497 VKPL 500


>gi|71979937 sialophorin [Homo sapiens]
          Length = 400

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 31/229 (13%)

Query: 88  KVANKIESIPVKGIIPSKKTKQKEVYPATPACTPS--NRLTAKGAEETLGPQKRKKPSEE 145
           +V+ K+ S+P       ++T     +PA P    S  +     G   T  P+   + S  
Sbjct: 97  EVSIKMSSVP-------QETPHATSHPAVPITANSLGSHTVTGGTITTNSPETSSRTSGA 149

Query: 146 ETGTKRSKMSKEQTR---PSCSAGASTSTAMGRSPPP----------QTSSSAPPNTSST 192
              T  S +   +     P   A  S  T+ G S PP           T ++ PP T +T
Sbjct: 150 PVTTAASSLETSRGTSGPPLTMATVSLETSKGTSGPPVTMATDSLETSTGTTGPPVTMTT 209

Query: 193 ESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFHATVATQTQFFHV 252
            SL+P +        ++     +            + + +   R M    V        V
Sbjct: 210 GSLEPSSGASGPQVSSVKLSTMMSPTTSTNASTVPFRNPDENSRGMLPVAVLVALLAVIV 269

Query: 253 KVLNINLKRKFIKKR--IIIISNYSKRNSLLEVNEASSVSEAGPDQTFE 299
            V  + L R+  K+R   +++S   KRN +++       + AGP Q  E
Sbjct: 270 LVALLLLWRRRQKRRTGALVLSRGGKRNGVVD-------AWAGPAQVPE 311


>gi|4507181 sialophorin [Homo sapiens]
          Length = 400

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 31/229 (13%)

Query: 88  KVANKIESIPVKGIIPSKKTKQKEVYPATPACTPS--NRLTAKGAEETLGPQKRKKPSEE 145
           +V+ K+ S+P       ++T     +PA P    S  +     G   T  P+   + S  
Sbjct: 97  EVSIKMSSVP-------QETPHATSHPAVPITANSLGSHTVTGGTITTNSPETSSRTSGA 149

Query: 146 ETGTKRSKMSKEQTR---PSCSAGASTSTAMGRSPPP----------QTSSSAPPNTSST 192
              T  S +   +     P   A  S  T+ G S PP           T ++ PP T +T
Sbjct: 150 PVTTAASSLETSRGTSGPPLTMATVSLETSKGTSGPPVTMATDSLETSTGTTGPPVTMTT 209

Query: 193 ESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFHATVATQTQFFHV 252
            SL+P +        ++     +            + + +   R M    V        V
Sbjct: 210 GSLEPSSGASGPQVSSVKLSTMMSPTTSTNASTVPFRNPDENSRGMLPVAVLVALLAVIV 269

Query: 253 KVLNINLKRKFIKKR--IIIISNYSKRNSLLEVNEASSVSEAGPDQTFE 299
            V  + L R+  K+R   +++S   KRN +++       + AGP Q  E
Sbjct: 270 LVALLLLWRRRQKRRTGALVLSRGGKRNGVVD-------AWAGPAQVPE 311


>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
          Length = 338

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 127 AKGAEETLGPQKRKKPSEEETGT---KRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSS 183
           A+GA   +G +KR +      G    KR K S++ T  +CSA  S   +  ++     SS
Sbjct: 120 ARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQERSKQKARRRTRSS 179

Query: 184 SAPPNTSSTESLKPLANRHATAS 206
           S+  ++SS+ S    ++  +++S
Sbjct: 180 SSSSSSSSSSSSSSSSSSSSSSS 202


>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
          Length = 341

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 127 AKGAEETLGPQKRKKPSEEETGT---KRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSS 183
           A+GA   +G +KR +      G    KR K S++ T  +CSA  S   +  ++     SS
Sbjct: 120 ARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQERSKQKARRRTRSS 179

Query: 184 SAPPNTSSTESLKPLANRHATAS 206
           S+  ++SS+ S    ++  +++S
Sbjct: 180 SSSSSSSSSSSSSSSSSSSSSSS 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,197,813
Number of Sequences: 37866
Number of extensions: 784523
Number of successful extensions: 6247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 172
Number of HSP's that attempted gapping in prelim test: 5574
Number of HSP's gapped (non-prelim): 783
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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