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Search of human proteins with 41281911
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281911 Ymer protein long isoform [Homo sapiens]
(482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281911 Ymer protein long isoform [Homo sapiens] 983 0.0
gi|28372509 Ymer protein short isoform [Homo sapiens] 334 1e-91
gi|148746195 trichohyalin [Homo sapiens] 67 4e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 65 1e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 3e-10
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 61 2e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 58 2e-08
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 57 4e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 56 8e-08
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 52 9e-07
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 52 9e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 52 2e-06
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 51 2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 3e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 6e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 6e-06
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 50 6e-06
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 50 6e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 50 6e-06
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 50 6e-06
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 49 1e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 49 1e-05
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 49 1e-05
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 49 1e-05
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 49 1e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 49 1e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 49 1e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 49 1e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 49 1e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 49 1e-05
>gi|41281911 Ymer protein long isoform [Homo sapiens]
Length = 482
Score = 983 bits (2542), Expect = 0.0
Identities = 482/482 (100%), Positives = 482/482 (100%)
Query: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK
Sbjct: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
Query: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE
Sbjct: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
Query: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHK 180
LQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHK
Sbjct: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHK 180
Query: 181 KEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPT 240
KEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPT
Sbjct: 181 KEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPT 240
Query: 241 ISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGE 300
ISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGE
Sbjct: 241 ISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGE 300
Query: 301 HRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQE 360
HRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQE
Sbjct: 301 HRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQE 360
Query: 361 EELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKA 420
EELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKA
Sbjct: 361 EELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKA 420
Query: 421 ANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHY 480
ANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHY
Sbjct: 421 ANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHY 480
Query: 481 KH 482
KH
Sbjct: 481 KH 482
>gi|28372509 Ymer protein short isoform [Homo sapiens]
Length = 306
Score = 334 bits (856), Expect = 1e-91
Identities = 163/185 (88%), Positives = 169/185 (91%)
Query: 298 QGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK 357
Q E ++++H P P + + D GMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK
Sbjct: 122 QEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK 181
Query: 358 LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKT 417
LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKT
Sbjct: 182 LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKT 241
Query: 418 AKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKG 477
AKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKG
Sbjct: 242 AKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKG 301
Query: 478 FHYKH 482
FHYKH
Sbjct: 302 FHYKH 306
Score = 300 bits (768), Expect = 2e-81
Identities = 182/332 (54%), Positives = 201/332 (60%), Gaps = 71/332 (21%)
Query: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK
Sbjct: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
Query: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE
Sbjct: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
Query: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCR----------- 169
LQEEKKRKKHFPEFPATRAYADSYYYED G + R + S P R
Sbjct: 121 LQEEKKRKKHFPEFPATRAYADSYYYED----GGMKPRVMKEAVSTPSRMAHRDQEWYDA 176
Query: 170 ---------------------------------LQRDGKTVKHKKEKPEHPLENLEEPEQ 196
+ + K K KE+ + L+ ++ +
Sbjct: 177 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQ-DP 235
Query: 197 HCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWET 256
K + +++S K D PH S ERP RP P ++ D +
Sbjct: 236 EWKPKTAKAANSKSKESDEPH---------HSKNERPARPPPPIMT---------DGEDA 277
Query: 257 KINHQTRNWEKQSRHQDRLSPKSSQKAGLHCK 288
H T N + +RH S S G H K
Sbjct: 278 DYTHFT-NQQSSTRH---FSKSESSHKGFHYK 305
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 287 CKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHR- 345
C++ DH + + + +L HD + ++ +E + +++ R
Sbjct: 18 CRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRY 77
Query: 346 -DQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKE 398
D E D EIA+++QE+ LA + + R Q +DE+IARLL +E + KK K+
Sbjct: 78 KDLEQQDCEIAQEIQEK--LAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKK 129
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 67.0 bits (162), Expect = 4e-11
Identities = 90/446 (20%), Positives = 184/446 (41%), Gaps = 68/446 (15%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAK----QLQEEDLKAQAQLQKRYKDLEQQ---DCEI 87
+QE E L ++ RL + + Q + Q +EE L + + +R ++LE+Q + E+
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 88 AQEIQEKLAIEAERRRIQE-----KKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
QE ++ L E E+RR QE +++E++ + +E++L E++ K+ E +
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQ--EEEQLLREEREKRRRQELERQYREEE 1144
Query: 143 SYYYED----GDQPGSRRARELGSGFSRPCRLQRDGKTV---KHKKEKPEHPLENLEEPE 195
E+ ++P RR +EL + LQ++ + + + +K + E + EE E
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Query: 196 --------------QHCSSKRSLSSSSSGKGRDNPHI----NNEQHERKRSTQERPRRPL 237
Q K RDN NEQ + +Q R R+
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ 1264
Query: 238 --LPTISGEVFLSTECDDWETKINHQTRNWEKQSRH---QDRLSPKSSQKAGLHCKEVVY 292
L + GE E + R W+++ RH +++L + ++A ++
Sbjct: 1265 QDLQHLLGE--------QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE 1316
Query: 293 GRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+ + E ++R R T EEQL ++E P R RD+++ +
Sbjct: 1317 EKQLLREEREEKRRRQETDRKFREEEQL-----------LQEREEQPLRRQERDRKFREE 1365
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
E+ + Q + L + +R + E + L E++ ++ +++ + D++ ++ E
Sbjct: 1366 ELRHQEQGRKFLEEEQRLR-----RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 413 WKPKTAKAANSKSKESDEPHHSKNER 438
+ + +E + + ER
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERER 1446
Score = 62.0 bits (149), Expect = 1e-09
Identities = 82/437 (18%), Positives = 187/437 (42%), Gaps = 33/437 (7%)
Query: 26 DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDC 85
+ L +E+ E Q+ R Q + + +QL+ E + + Q +R ++ E+++
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 86 EIAQEIQEKLAIEAERRRIQEKKDEDIAR---------LLQEKELQEEK--KRKKHFPEF 134
++ +E +E+ + RR Q ++++ + R L +E++L+ E+ +R++
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 135 PATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEP 194
R + +E + R R R L+R+ +T +H++E+ + L+ +E
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 195 EQHCS-SKRSLSSSSSGKGRDNPHINNEQHERK--RSTQERPRRPLLPTISGEVFLSTEC 251
E+ K + R + EQ ER+ R ++ L + E L E
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 252 DDW-ETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHR-KRRHRPR 309
++ E + + +Q R + RL + ++ ++ + R+ + + R KR R
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEER-----RDQLLKREEERRQQRLKREQEER 597
Query: 310 TPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVD 369
+ EE L + + +K R Q+ +E + ++++L Q +
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERR----QQLLKSEEQEERRQQQLRREQQE 653
Query: 370 MRAAQVAQDEEIARLLM------AEEKKAYKKAKEREKSSLDK-RKQDPEWKPKTAKAAN 422
R ++ ++EE RL EE++ + A+E ++ + ++ + + P+W+ + A+
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
Query: 423 SK-SKESDEPHHSKNER 438
++ SK P + +R
Sbjct: 714 ARQSKVYSRPRKQEGQR 730
Score = 61.6 bits (148), Expect = 2e-09
Identities = 94/455 (20%), Positives = 187/455 (41%), Gaps = 67/455 (14%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAK----QLQEEDLKAQAQLQKRYKDLE---QQDCEI 87
+QE E L ++ R + + Q K Q +EE L + ++R ++ E +++ E+
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 88 AQEIQEKLAIEAERRRIQE------KKDEDIARLLQEKE-LQEEKKRKKHFPEFPATRAY 140
QE ++ L E E+RR QE KKDE L QE+E L E++ K+ E
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDE----LQQEEEQLLREEREKRRLQERERQYRE 1052
Query: 141 ADSYYYED----GDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQ 196
+ E+ G++ +RR +EL + + LQ++ + + +E+PE +E E+
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL--LREEPEK--RRRQERER 1108
Query: 197 HCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWET 256
C + L + + E+ +R+R ER R E L E +
Sbjct: 1109 QCREEEELQQ------EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 257 K--INHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFS 314
+ + Q R E+ + +++L + +K + + Q + RK+R+R
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Query: 315 -----------------------ESEEQLHLHDAGMKPRVMKEAVS-TPSRMAHRDQE-- 348
E+E+ L D+ ++ R ++ + RD+E
Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282
Query: 349 ---WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLD 405
W + R EEE L + A + + + + L+ EE++ ++ +E ++ +
Sbjct: 1283 RRRWQQRD--RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 406 KRK--QDPEWKPKTAKAANSKSKESDEPHHSKNER 438
+ + Q+ E +P + + K +E + H + +
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Score = 60.8 bits (146), Expect = 3e-09
Identities = 91/490 (18%), Positives = 199/490 (40%), Gaps = 80/490 (16%)
Query: 3 EVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK-- 60
E+ ++ +L G + R LE +QE E L ++ R + + Q +
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 61 --QLQEEDLKAQAQLQKRYKDLEQQ---DCEIAQEIQEKLAIEAERRRIQE-----KKDE 110
Q +EE L + + ++R ++LE+Q + E+ QE ++ L E E+RR QE +++E
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 111 DIAR----LLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPG------------- 153
++ + LL+E++ + ++R++ + E + Y D DQ
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 154 ------------SRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLE---------NLE 192
+ + R+L R + Q+D + + ++++ + E +
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 193 EPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
E EQ ++ + K ++ + E+ E KR QE R+ E L E +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK-----FREEEQLLQERE 1349
Query: 253 DWETKINHQTRNW-EKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTP 311
+ + + R + E++ RHQ++ GR + E R RR R
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQ------------------GRKFLEEEQRLRRQE-RER 1390
Query: 312 PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMR 371
F + E+QL + + R ++ + +Q+ E RK +EEE + +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDR-----KFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 372 AAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEP 431
+ +++++ + + ++ + +ERE+ L ++++D ++ + + +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 432 HHSKNERPAR 441
+++ P R
Sbjct: 1506 QELRSQEPER 1515
Score = 58.9 bits (141), Expect = 1e-08
Identities = 80/431 (18%), Positives = 177/431 (41%), Gaps = 68/431 (15%)
Query: 15 KEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQ 74
+E R + E+ L+ QE+ Q+ + ++ + Q+ ++ +EE + Q + +
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 75 KRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEF 134
++ + EQQ+ Q++ RR QE++ E R QE+E +E++ R+
Sbjct: 323 EQQERREQQEERREQQL----------RREQEERREQQLRREQEEERREQQLRR------ 366
Query: 135 PATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEE- 193
+Q RR ++L R +L+R+ + + ++ + E L ++
Sbjct: 367 ---------------EQEEERREQQL----RREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 194 -PEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
EQ ++ L + + ++HE++R Q R E
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE------------QEERR 455
Query: 253 DW-----ETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHR 307
DW ET+ + Q R KQ +D+ + + L +E ++ + + R+ +
Sbjct: 456 DWLKREEETERHEQER--RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Query: 308 PRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQ 367
R EE+ L + R+ E + R+QE ++ ++ +E+ L +
Sbjct: 514 RREQRLKRQEEEERL-----QQRLRSE------QQLRREQEERREQLLKREEEKRLEQER 562
Query: 368 VDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKE 427
+ R + Q+E +LL EE++ ++ K ++ L++R + E + + + +
Sbjct: 563 REQRLKR-EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 428 SDEPHHSKNER 438
+EP + ++
Sbjct: 622 REEPEEERRQQ 632
Score = 58.9 bits (141), Expect = 1e-08
Identities = 81/399 (20%), Positives = 163/399 (40%), Gaps = 62/399 (15%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQD 84
++ L L+ +E+E + RL + + + ++ +++ LK++ Q ++R + L ++
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPE--EERRQQLLKSEEQEERRQQQLRREQ 651
Query: 85 CEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSY 144
E +++L E E R++++ + +E+EL EE++ + ++ +
Sbjct: 652 QE---RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR----ERIKSRIPKW 704
Query: 145 YYEDGDQPGSRRARELGSGFSRPCRL--QRDGKTVKHKKEKPEHPLENLEEPEQHCSSKR 202
++ + +R+++ +SRP + QR + + K+ + E L+ EE H
Sbjct: 705 QWQLESEADARQSKV----YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH----- 755
Query: 203 SLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQT 262
+ RD + + +R Q RP L + Q
Sbjct: 756 -RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL----------------REQRERQL 798
Query: 263 RNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHL 322
R E+Q R Q R P+ +K + R+RR R + F E EEQL
Sbjct: 799 RAEERQQREQ-RFLPEEEEK---------------EQRRRQRREREKELQFLEEEEQLQR 842
Query: 323 HDAGMKPRVMKEAVSTP-----SRMAHRDQEW-YDAEIARKLQEEELL---ATQVDMRAA 373
+ + + ++ + S+ RDQ+W + E RK + L A Q +R
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902
Query: 374 QVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
Q EE L E +K ++ +ER+ ++ +Q+ E
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE 941
Score = 57.4 bits (137), Expect = 3e-08
Identities = 87/442 (19%), Positives = 180/442 (40%), Gaps = 81/442 (18%)
Query: 21 FAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQL---QEEDLKAQAQLQKRY 77
F LED L +Q+++H L +R+R + + +EE L+ + Q + +
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 78 KDLEQQDCE--IAQEIQEKLA-------IEAERRRIQEKKDEDIA-----RLLQEKELQE 123
+D + Q+ + + +E +EK E + +QE++++ + R +E+EL+
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 124 EKKRKKHFPEFPATRAY--ADSYYYEDGDQPGSRRARELGSGFSRPCR-----LQRDGKT 176
+++ +K E R + E+ R ++L R R L R +
Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 177 VKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRP 236
K ++E E + E + ++ L K R+ + E+ E++ QER R+
Sbjct: 1430 RKFREE--EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 237 LLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDH 296
L + E ++ Q R +++ R Q+ S + +K +
Sbjct: 1488 L---------------EEEQQLRRQER--DRKFREQELRSQEPERKF----------LEE 1520
Query: 297 GQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIAR 356
Q HR++R R F + E+QL + G + R RD+++ + E R
Sbjct: 1521 EQQLHRQQRQR----KFLQEEQQLRRQERGQQ------------RRQDRDRKFREEEQLR 1564
Query: 357 KLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPK 416
+ +EE+ L+ Q E R EE+K ++ +ER+ +++ + E + +
Sbjct: 1565 QEREEQQLSRQ------------ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 417 TAKAANSKSKESDEPHHSKNER 438
+ + K +E ++ + E+
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQ 1634
Score = 56.2 bits (134), Expect = 6e-08
Identities = 94/446 (21%), Positives = 181/446 (40%), Gaps = 65/446 (14%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQ-----LQEEDLKAQAQLQKRYKDLEQQDCEI 87
LQE+E E L + + ++ + Q+ +Q +E++L++Q +K ++ +Q +
Sbjct: 1470 LQERE-EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 88 AQE--IQEKLAIEAERRRIQEKKDEDIA-----RLLQEKELQE----EKKRKKHFPEFPA 136
Q +QE+ + + R Q ++D D +L QE+E Q+ E+ RK E
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Query: 137 TRAYADSYYYEDGDQ----PGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLEN-- 190
R + + ED Q G ++ R+ R + + D + ++ ++E+ H E
Sbjct: 1589 RRQEQERKFMEDEQQLRRQEGQQQLRQ-----ERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 191 --LEEPEQHCSSKRS--LSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVF 246
LEE Q +R L K R+ + E E++ QER R+
Sbjct: 1644 KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK----------- 1692
Query: 247 LSTECDDWETKINHQTRN----WEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHR 302
+ E ++ Q R E+Q + L K ++ L +E + Q +R
Sbjct: 1693 ----FREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR-QETEQEQLRRQERYR 1747
Query: 303 KRRHRPRTPPFSESEEQLHLHDAGMKPR----VMKEAVSTPSRMAHRDQEWYDAEIARKL 358
K + P E E+QL + K R + +E R D+++ + E R+
Sbjct: 1748 KILEEEQLRPERE-EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 359 QEEELLATQVDMRAAQVAQDEEIARL------LMAEEKKAYKKAKEREKSSLDKRKQDPE 412
+EE+ L Q R + +EE +L L E + Y+ ++ +R++
Sbjct: 1807 REEQQLRPQ--QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL 1864
Query: 413 WKPKTAKAANSKSKESDEPHHSKNER 438
W+ + K + ++ E H + ++
Sbjct: 1865 WQEEEQKRRQERERKLREEHIRRQQK 1890
Score = 54.7 bits (130), Expect = 2e-07
Identities = 80/411 (19%), Positives = 162/411 (39%), Gaps = 60/411 (14%)
Query: 60 KQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEK 119
+QL+EE Q + QKR ++Q+ E+A+ ++ E +R ++++DE++ R Q +
Sbjct: 127 RQLEEEP--GQRRRQKR----QEQERELAEGEEQSEKQERLEQRDRQRRDEELWR--QRQ 178
Query: 120 ELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRAREL---GSGFSRPCRLQRDGKT 176
E QE ++R+ + + + + ++ + D +Q R EL G + R +R +
Sbjct: 179 EWQEREERRAEEEQLQSCKGH-ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 177 VKHKKEK--------------------PEHPLENLEEPE-------QHCSSKRSLSSSSS 209
+ ++EK P+ E EE E Q +R
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 210 GKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQS 269
+ R + +Q E +R QE R + E + Q R +++
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQ-----------QERREQQEERREQQLRREQEER 346
Query: 270 RHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKP 329
R Q + ++ +E R+ Q E R+ + R ++ +
Sbjct: 347 REQQLRREQEEER-----REQQLRRE--QEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 330 RVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEEL--LATQVDMRAAQVAQDEEIARLLMA 387
++ +E + R+Q+ + R+ QEEE + + R ++ +++E R +
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459
Query: 388 EEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 438
E++ + +ER K L KR Q+ E + + K + +E E + R
Sbjct: 460 REEETERHEQERRKQQL-KRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Score = 49.7 bits (117), Expect = 6e-06
Identities = 93/442 (21%), Positives = 184/442 (41%), Gaps = 48/442 (10%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAK----QLQEEDLKAQAQLQKRYKDLEQQ---DCEI 87
+QE E L ++ R + + Q K Q +EE L + + ++R ++ E+Q + E+
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 88 AQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR-KKHFPEFPATRAYADSYYY 146
QE ++ L E E RR QE + + +E+ELQ+E+++ + PE +
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQ----YRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 147 ED----------GDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQ 196
E+ ++ RR +EL + +Q++ + + +E+PE +E E+
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL--LREEPEK--RRRQELER 1168
Query: 197 HCSSKRSLSSSSSGKGRDNPHINNEQHERK-RSTQERPRRPLLPTISGEVFLSTECDDWE 255
+ L R+ ++ ER+ R +E R+ E S WE
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE 1228
Query: 256 TKINHQTR----------NWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRR 305
+ + R N + + +L + SQ+ H RD Q E R+ +
Sbjct: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ-ERRRWQ 1287
Query: 306 HRPRTPPFSESEEQLHLHDAGMKPR-------VMKEAVSTPSRMAHRDQEWYDAEIARKL 358
R R P E E+ +A + R +++E R D+++ + E +
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
Query: 359 QEEELLATQVDMR--AAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPK 416
+EE+ L Q R + + +E R + EE++ ++ +ER+ +++ + E + +
Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 417 TAKAANSKSKESDEPHHSKNER 438
+ + K +E +E S+ ER
Sbjct: 1408 LRQDRDRKFRE-EEQQLSRQER 1428
Score = 48.9 bits (115), Expect = 1e-05
Identities = 80/393 (20%), Positives = 161/393 (40%), Gaps = 68/393 (17%)
Query: 47 QRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQE 106
Q+ R + D ++ ++E K + L+K + L++++ + +E+QE E ++++
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE------EEEQLRK 280
Query: 107 KKDEDIARLLQEKELQ------EEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRAREL 160
+ +++ R QE+E Q E++ R+K Q RR +
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRK---------------------QEEERREQ-- 317
Query: 161 GSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINN 220
Q + + + ++E+ E E EQ ++ L + R+ +
Sbjct: 318 ----------QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ-QLRR 366
Query: 221 EQHERKRSTQERPRRPLL--PTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPK 278
EQ E +R Q R + L + E L E + + Q R E+Q R + +L +
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRRE---QQLRREQQLRR-EQQLRREQQL--R 420
Query: 279 SSQKAGLHCKEVVYGRDHGQ--GEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAV 336
Q+ +E + + H Q E R +R + + + EE+ H+ + + +K
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK--- 477
Query: 337 STPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKA 396
RDQE E KL+EEE Q + R Q+ +++E R + ++ ++
Sbjct: 478 --------RDQEEERRERWLKLEEEE-RREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 397 KEREKSSLDKRKQDPEWKPKTAKAANSKSKESD 429
++R +S R++ E + + K K E +
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Score = 42.4 bits (98), Expect = 0.001
Identities = 63/303 (20%), Positives = 115/303 (37%), Gaps = 55/303 (18%)
Query: 141 ADSYYYEDGDQPG---SRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQH 197
A + YY G G +RAR G R Q + + + E + LE EEP Q
Sbjct: 82 AQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQ---RRFEPRDRQLE--EEPGQR 136
Query: 198 CSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETK 257
KR +G EQ E++ ++R R+ + L + +W+ +
Sbjct: 137 RRQKRQEQERELAEGE-------EQSEKQERLEQRDRQ------RRDEELWRQRQEWQER 183
Query: 258 INHQTRNWEKQS--RHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSE 315
+ + QS H+ P Q L +E++ R G+ E +++R + F E
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQ---LRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 316 SEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQV 375
EE+ EW E + +EEE L + R ++
Sbjct: 241 EEEK----------------------------EWRKRETVLR-KEEEKLQEEEPQRQREL 271
Query: 376 AQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSK 435
++EE R L +E + ++ +E+++ L + +Q + + + + +E E +
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 436 NER 438
ER
Sbjct: 332 EER 334
Score = 32.0 bits (71), Expect = 1.3
Identities = 27/132 (20%), Positives = 65/132 (49%), Gaps = 31/132 (23%)
Query: 23 VLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ 82
+LE+ L +EQ++ +R+R + + Q+ ++ +E+ L++Q + +++++ EQ
Sbjct: 1749 ILEEEQLRPEREEQQLRRQ-----ERDRKFREEEQLRQEREEQQLRSQ-ESDRKFREEEQ 1802
Query: 83 QDCEIAQEI-------------QEKLAIEAERRRIQEKKD------------EDIARLLQ 117
E ++ +E+L +E + +R+++++D E R Q
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQ 1862
Query: 118 EKELQEEKKRKK 129
E +EE+KR++
Sbjct: 1863 ELWQEEEQKRRQ 1874
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 65.5 bits (158), Expect = 1e-10
Identities = 83/384 (21%), Positives = 153/384 (39%), Gaps = 35/384 (9%)
Query: 60 KQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEK 119
K+L+EE K + + Q+ K+ +++ E +E + + E ER R +E++ E +EK
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERR---ERERERERERERE------KEK 339
Query: 120 ELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKH 179
E + E++R + D D D+ R+ + SR RD + +
Sbjct: 340 ERERERERDRDRDRTKERDRDRDRERDRDRDR---ERSSDRNKDRSRSREKSRDRERERE 396
Query: 180 KKEKPEHPLENLEEPEQHCSSKRSLS-SSSSGKGRDNPHINNEQHERKRSTQERPRRPLL 238
++ + E E E E+ +R K RD + +ER++ ER R
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK--LERKLR--- 451
Query: 239 PTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQ 298
E +WE + +TR +EK++ ++ + +++A KE + D +
Sbjct: 452 ---EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEA-KRLKEFLEDYDDDR 507
Query: 299 GEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKL 358
+ + R + E+++ + K R +E R+ DAE+ R
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADERDRK-REKEELEEIRQRLLAEGHPDPDAELQRME 566
Query: 359 QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTA 418
QE E R Q+ Q+ E +EE++ K+ KE ++ + +++PE KP
Sbjct: 567 QEAE------RRRQPQIKQEPE------SEEEEEEKQEKEEKREEPMEEEEEPEQKPCLK 614
Query: 419 KAANSKSKESDEPHHSKNERPARP 442
S S N P P
Sbjct: 615 PTLRPISSAPSVSSASGNATPNTP 638
Score = 42.7 bits (99), Expect = 7e-04
Identities = 40/220 (18%), Positives = 92/220 (41%), Gaps = 18/220 (8%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDC----EIAQ 89
+++E E +R R + + + ++ + E + + + +KR ++ +++D ++ +
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Query: 90 EIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDG 149
+++EK A ER + E ++ R +++ +EE++R++ E + + + Y +D
Sbjct: 449 KLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED-YDDDR 507
Query: 150 DQPGSRRARELGSGF-SRPCRLQRDGKTVKHKKEKPEH------------PLENLEEPEQ 196
D P R L R ++ D + K +KE+ E P L+ EQ
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ 567
Query: 197 HCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRP 236
+R + + E+ E++ E P
Sbjct: 568 EAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEP 607
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 63.9 bits (154), Expect = 3e-10
Identities = 82/426 (19%), Positives = 179/426 (42%), Gaps = 48/426 (11%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
Q QE E + ++ R + + ++ E K + +++ +D E++ E + ++E
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 408
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPG 153
K ER R QEK E + ++ +EK++QE++K+ TR + E+
Sbjct: 409 K----EERMREQEKMWEQVEKMREEKKMQEQEKK---------TRDQEEKMQEEE----- 450
Query: 154 SRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSS-----S 208
R RE R +++ + +T++ ++EK + EN+ E E+ ++ L
Sbjct: 451 --RIRE------REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 209 SGKGRDNPHINNEQHERKRSTQE-------RPRRPLLPTISGEVFLSTE-CDDWETKINH 260
K ++ EQ E+ R +E R+ + +++ E D E K+
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 261 QTRNWEKQSRHQDRLS----PKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSES 316
Q EK+++ Q++ + K ++ + +E + ++ + + + E
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 317 EEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYD---AEIARKLQEEELLATQVDMRAA 373
EE++ + M+ + K ++ W E KL E E + Q M+
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 374 Q--VAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEP 431
+ + + E++ + +EKK + + K RE+ S+ +R++ + + + K +E +E
Sbjct: 683 EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEK 742
Query: 432 HHSKNE 437
+ E
Sbjct: 743 MQEQEE 748
Score = 55.8 bits (133), Expect = 8e-08
Identities = 68/377 (18%), Positives = 164/377 (43%), Gaps = 21/377 (5%)
Query: 63 QEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKK--DEDIARLLQEKE 120
QE++L+ Q + + K+L +Q+ E QE +EK+ + E+ R QE+K ++ QEK+
Sbjct: 326 QEKELREQEKELREQKELREQE-EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHK 180
++E++++ + E R + + ++ R RE + + ++ R+ K ++ +
Sbjct: 385 MREQEQKMRDQEE----RMWEQDERLREKEE----RMREQEKMWEQVEKM-REEKKMQEQ 435
Query: 181 KEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPT 240
++K E ++E E+ ++ + + ++ ++ ++ LP
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 241 ISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGE 300
+++ + + E KI WE++ + +D+ +K +++ D +
Sbjct: 496 QKEKLWEQEKMQEQEEKI------WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 301 HRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQE 360
K R + + E + + K +E + RM R+++ + E + QE
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 361 EELLATQVDMRAAQVAQDEEIARLLMAEEK--KAYKKAKEREKSSLDKRKQDPEWKPKTA 418
E++ + M+ + E+ ++ EEK + +K E+E+ ++++ PE K K
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL-PEQKEKLW 668
Query: 419 KAANSKSKESDEPHHSK 435
+ + +E + K
Sbjct: 669 EHEKMQEQEKMQEQEEK 685
Score = 50.1 bits (118), Expect = 5e-06
Identities = 72/388 (18%), Positives = 156/388 (40%), Gaps = 37/388 (9%)
Query: 56 LQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARL 115
LQ QEE+L+ Q + ++ ++ + E +E + K+ + E+ QEK+ +
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLRE---- 325
Query: 116 LQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGK 175
QEKEL+E++K + E + +Q R +E + + RL K
Sbjct: 326 -QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQE-EKMWRQEERLWEQEK 383
Query: 176 TVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRR 235
++ +++K E + E ++ K + + E+K QE+ R
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE---QVEKMREEKKMQEQEKKTR 440
Query: 236 PLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRD 295
D E K+ + R E++ + ++ Q+ + +E +
Sbjct: 441 -----------------DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE-----E 478
Query: 296 HGQGEHRKRRHRPRTPPFSES-EEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEI 354
+ + K + R P E EQ + + K +E + M ++++ + E
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 538
Query: 355 ARKLQEEELLATQVDMRAAQVA---QDEEIARLLMAEEKKAY-KKAKEREKSSLDKRKQD 410
R+ QE+++ + MR + Q+E + + +EKK + ++ K RE+ + +R++
Sbjct: 539 MRE-QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 411 PEWKPKTAKAANSKSKESDEPHHSKNER 438
+ + + K +E +E + E+
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEK 625
Score = 44.7 bits (104), Expect = 2e-04
Identities = 72/397 (18%), Positives = 160/397 (40%), Gaps = 54/397 (13%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQ 92
++EQE ++ + +Q + + QEE ++ + ++++R K + +++ E +E +
Sbjct: 413 MREQEKMWEQVEKMREEKKMQEQEKKTRD-QEEKMQEEERIREREKKMREEE-ETMREQE 470
Query: 93 EKLAIEAERRRIQEKKDEDIARLLQEKEL----------------QEEKKRKKHFPEFPA 136
EK+ + E QE+K+ RL ++KE QEEK R +
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 137 TRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQ 196
+ + E DQ + + + +R K + +++K E + E E+
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 197 HCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWET 256
++ + R+ + EQ E+ + +E+ + E WE
Sbjct: 591 MREREKKM--------REEEEMMREQEEKMQEQEEKMQEQ-------------EEKMWEQ 629
Query: 257 KINHQTRN---WEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPF 313
+ Q + WE++ + ++ Q+ KE ++ EH K + + +
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW-------EHEKMQEQEK---M 679
Query: 314 SESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVD-MRA 372
E EE++ + M+ + ++ T + R++E + +EEE++ Q + M+
Sbjct: 680 QEQEEKIWEQEK-MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE 738
Query: 373 AQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQ 409
+ E+ + EEK ++ K E+ L ++K+
Sbjct: 739 QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Score = 31.6 bits (70), Expect = 1.7
Identities = 26/124 (20%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Query: 7 DQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDL--QVAKQLQE 64
+Q +LP KE + +++ +QEQE + +++ Q K +E
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQ---EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 65 EDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKD-EDIARLLQEKELQE 123
E ++ + + + +++ ++ E QE +EK+ + E QE+K E ++ +++ L E
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772
Query: 124 EKKR 127
+K++
Sbjct: 773 QKEK 776
Score = 30.0 bits (66), Expect = 4.9
Identities = 18/104 (17%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
Query: 23 VLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ 82
+ E + QEQE + ++ ++ + ++ +E + + ++Q++ + +++
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 83 QDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKK 126
Q+ E+ ++ +EK+ + E+ Q++ E +L + +++QE++K
Sbjct: 746 QEEEMWEQ-EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 61.2 bits (147), Expect = 2e-09
Identities = 91/447 (20%), Positives = 182/447 (40%), Gaps = 61/447 (13%)
Query: 30 AHSLQEQEIEHHLASNVQ-RNRLVQHDLQVAKQLQEEDLKAQAQ---LQKRYKDLEQQDC 85
AH LQE+E +H LA +N +H +A++ E+ K + + +Q+ ++LEQ++
Sbjct: 540 AHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREA 599
Query: 86 EIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYY 145
E+ +K+ E R QE K+ + R+LQE E ++K ++ + T A ++
Sbjct: 600 EL-----QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFK 654
Query: 146 YEDGDQPGSRRARELGSGF---SRPCRLQRDGKTVKHKKEKPEHPLENLEEPE------- 195
D + EL F + +L+++ K ++ + + E ++ E +
Sbjct: 655 DIDIED-----LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPL 709
Query: 196 -QHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDW 254
+ ++ + + ++ I Q ER+++ + + R + +
Sbjct: 710 IKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNR-------MSRMLEDRDLFVM 762
Query: 255 ETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFS 314
K Q+ EK + ++RL+ E + R + RK R
Sbjct: 763 RLKAARQSVYEEKLKQFEERLA------------EERHNRLEERKRQRKEERRITYYREK 810
Query: 315 ESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYD-AEIARKLQEEELLATQVDMRAA 373
E EEQ + +K R +E + A R++E + E +KL+E E Q ++
Sbjct: 811 EEEEQRRAEEQMLKEREERER----AERAKREEELREYQERVKKLEEVERKKRQRELEIE 866
Query: 374 QVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDP----EWK--PKTAKAANSKSKE 427
+ + E R L + + K ++ ++ S ++ P EW+ P + + ++
Sbjct: 867 ERERRREEERRL-GDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD 925
Query: 428 SDEPHHSKNERPARPPPPIMTDGEDAD 454
D H ERP R + D ED +
Sbjct: 926 EDRSHRRDEERPRR-----LGDDEDRE 947
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 57.8 bits (138), Expect = 2e-08
Identities = 76/405 (18%), Positives = 163/405 (40%), Gaps = 32/405 (7%)
Query: 42 LASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAER 101
L VQ N L + + ++L+E++ K + Q +K ++ E+ +E + K+ + E+
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER-----LREQEGKMREQEEK 277
Query: 102 RRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELG 161
R QEK+ + QEKEL+E++K + + + +Q R +E
Sbjct: 278 MRRQEKRLRE-----QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE-E 331
Query: 162 SGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNE 221
+ + RL K ++ +++K E + E ++ K + E
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 222 QHERKRSTQERPRRPLLPTISGEVFLSTECDDWE--------TKINHQTRNWEKQSRHQD 273
+ R+R + R + E E + WE ++ Q +Q + Q+
Sbjct: 392 ERIREREKKMREEEETMRE-QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 274 RLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMK 333
+ Q+ + +E ++G++ K R E E+Q+ + M+ + K
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR---------EQEDQMWEQEEKMRDQEQK 501
Query: 334 EAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAY 393
RM +D+ + E R +++++ + MR + Q++E E+ +
Sbjct: 502 -MWDQEERMWEQDERLREKE-ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 394 KKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 438
++ +EREK ++ + E + K + K +E +E + E+
Sbjct: 560 ERMREREKKMREEEEMMREQEEK-MQEQEEKMREQEEKMWEQEEK 603
Score = 56.6 bits (135), Expect = 5e-08
Identities = 77/437 (17%), Positives = 175/437 (40%), Gaps = 24/437 (5%)
Query: 47 QRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQE 106
Q RL + + ++ +Q E++L+ Q +L+++ + +++Q+ E E +EK+ + E+ QE
Sbjct: 281 QEKRLREQEKELREQ--EKELREQKKLREQEEQMQEQE-EKMWEQEEKMREQEEKMWRQE 337
Query: 107 KKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSR 166
++ + + ++E+E + + ++ + + R + ++ + +E R
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 167 PCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERK 226
+++ + +T++ ++EK + EN+ E E+ ++ L EQ E+
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM--QEQEEKI 455
Query: 227 RSTQERPRRPLLPTISGEVFLSTECDDW--ETKINHQTRNWEKQSRHQDRLSPKSSQKAG 284
+E+ R E E W E + + WE++ + +D+ Q+
Sbjct: 456 WEQEEKIR-------DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE-- 506
Query: 285 LHCKEVVYGRDHG--QGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRM 342
E ++ +D + E R R + + E+ + K +E + RM
Sbjct: 507 ----ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 343 AHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKS 402
R+++ + E + QEE++ + MR + E+ ++ EEK ++ K E+
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 403 SLDKRKQDPE--WKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTN 460
DK ++ E W+ + + E + E R M E+
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Query: 461 QQSSTRHFSKSESSHKG 477
Q + E +G
Sbjct: 683 MQGQEEKMREQEEKMRG 699
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/411 (16%), Positives = 165/411 (40%), Gaps = 24/411 (5%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
Q QE E + ++ R + + ++ E K + +++ +D E++ E + ++E
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 370
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPG 153
K ER R QEK E ++ +E+ ++E +K+ + E + ++
Sbjct: 371 K----EERMREQEKMWEQEEKMQEEERIREREKKMREEEET-----------MREQEEKM 415
Query: 154 SRRARELGSGFSRPCRLQR--DGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGK 211
++ + + + QR + K ++EK + E + E E+ + +
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 212 GRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTE-CDDWETKINHQTRNWEKQSR 270
R E ++ + R + + ++ E + E ++ Q + W+++ +
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
Query: 271 HQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPR 330
++ + +K +E + R+ + R+++ R E EE++ + M+ +
Sbjct: 536 MREEKKTQEQEKKTWDQEEKM--REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 331 VMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEK 390
K ++ W E + +EE+ + Q +M Q + +E + +E+
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 391 K---AYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 438
K +K +E+E+ + ++ E + K + K +E +E + E+
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEK-MQGQEEKMREQEEKMRGQEEK 703
Score = 34.7 bits (78), Expect = 0.20
Identities = 30/166 (18%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
+E+ E Q ++ + + ++ +Q +E+ ++ Q ++ ++ Q+ E E +E
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPG 153
K+ + E+ R QE+K + ++E+E + + + +K + R + + ++ ++
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE-EKMW 712
Query: 154 SRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCS 199
+ + G ++ + ++ +KEK + E L E E+ CS
Sbjct: 713 GQEEKMWGQE-----EMREKEERIRDQKEKMQ---ERLPEHEERCS 750
Score = 30.4 bits (67), Expect = 3.7
Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 12/119 (10%)
Query: 19 RDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYK 78
R+ + E+ + +E+ E Q ++ + + +++QE++ K Q +K ++
Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE----EKMQEQEEKMWEQEEKMWE 620
Query: 79 DLE----QQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKEL----QEEKKRKK 129
E Q+ E+ E +EK+ + E+ QE+K + ++E+E QEEK R++
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Score = 29.6 bits (65), Expect = 6.4
Identities = 19/95 (20%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQ 92
++E+E ++ + + + Q QEE ++ Q + ++ Q+ E E +
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 93 EKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
EK+ + E ++QE+++ QE+++QE++++
Sbjct: 616 EKMWEQEEEDKMQEQEE---MMWEQEEKMQEQEEK 647
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 57.0 bits (136), Expect = 4e-08
Identities = 91/406 (22%), Positives = 182/406 (44%), Gaps = 39/406 (9%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEK 94
EQ+++ L ++++ + ++ DL+ AK+ E DLK Q+ D+E ++ +++++K
Sbjct: 1032 EQQVDD-LEGSLEQEKKIRMDLERAKRKLEGDLKL---AQESTMDIENDKQQLDEKLKKK 1087
Query: 95 LAIEAERRRIQEK-KDEDIARLLQEKELQEEKKRKKHF-PEFPATRAYADSYYYEDGD-- 150
E E +Q K +DE + +K+++E + R + E A RA + D
Sbjct: 1088 ---EFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
Query: 151 ---QPGSRRARELGSGFSRPCRL--QRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLS 205
+ S R E G S + +R+ + K +++ E L++ E K + S
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQH-EATAATLRKKHADS 1203
Query: 206 SSSSGKGRDNPHINNEQHERKRSTQERPRRPL---LPTIS-GEVFLSTECDDWETKINHQ 261
+ G+ DN ++ E+++S + L + T+S + L C E +++
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 1263
Query: 262 TRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLH 321
E+Q R ++ ++Q+A L + Y R + + + F++ E+L
Sbjct: 1264 KTKEEEQQR---LINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL- 1319
Query: 322 LHDAGMKPRVMKEAVSTPSRMAHRDQ-EWYDAEIARKLQEEELLATQVDMRAAQVAQDEE 380
R ++E + S +AH Q +D ++ R+ EEE A + +++ A + E
Sbjct: 1320 -------KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEA-KAELQRAMSKANSE 1371
Query: 381 IARLLMAEEKKAYKKAKERE--KSSLDKRKQDPEWKPKTAKAANSK 424
+A+ E A ++ +E E K L +R QD E + +A N+K
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE---EHVEAVNAK 1414
Score = 31.6 bits (70), Expect = 1.7
Identities = 25/124 (20%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 14 VKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQL 73
+ ++ A L+ + +S Q E + ++ + + ++ K+ EE++KA++ L
Sbjct: 1274 INDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSAL 1333
Query: 74 QKRYKDLEQQDCEIAQE-IQEKLAIEAERRRIQEKKDEDIAR---------LLQEKELQE 123
+ + DC++ +E +E+ +AE +R K + ++A+ + + +EL+E
Sbjct: 1334 AHALQS-SRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 124 EKKR 127
KK+
Sbjct: 1393 AKKK 1396
Score = 30.8 bits (68), Expect = 2.9
Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 21/113 (18%)
Query: 33 LQEQEIEHHLASNVQR-NRLVQHDLQVAKQLQE--------EDLKAQAQLQKRY------ 77
LQ Q LA +R ++L++ +Q+ +++E E++ A+ +KR
Sbjct: 893 LQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 952
Query: 78 ---KDLEQQDCEIAQEIQEKLAIEAERRRIQEKK---DEDIARLLQEKELQEE 124
KD++ + +A+ +EK A E + + + E+ DE IA+L +EK+ +E
Sbjct: 953 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1005
Score = 30.4 bits (67), Expect = 3.7
Identities = 18/63 (28%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 54 HDLQ-VAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDI 112
H+L+ + KQ+++E + QA L++ LE ++ +I + E +++E R +KDE+I
Sbjct: 1528 HELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1587
Query: 113 ARL 115
++
Sbjct: 1588 DQM 1590
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 55.8 bits (133), Expect = 8e-08
Identities = 86/393 (21%), Positives = 161/393 (40%), Gaps = 34/393 (8%)
Query: 59 AKQLQEEDLKAQAQLQKRYKDLEQQDC--EIAQEIQEKLAIEAERRRIQEKKDEDIARLL 116
AK+ + + K + + +K+ +D ++ D E+ + E I+A+R + K E+
Sbjct: 32 AKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTEN----- 86
Query: 117 QEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRAR---ELGSGFSRPCRLQRD 173
E+E + K+KK + DS ED D + A+ E+ SG +
Sbjct: 87 NEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKL 146
Query: 174 GKTVKHKKEKPEHPLENLEEPEQHCSS--KRSLSSSSSGKGRDNPHINNEQHERKRSTQE 231
K K K +K + EE E + +RS +SS G ++ + +K++ +
Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKN 206
Query: 232 RPRRPLLPTISGEVFLSTECDDWETKINHQT-RNWEKQSRHQDRLSPKSSQKAGLHCKEV 290
+P P I E DD KI + EK+ R + + + ++ L KE
Sbjct: 207 KPG----PNIES----GNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258
Query: 291 VYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLH-DAGMKPRVMKEAVSTPSRMAHRDQEW 349
+ + G+ + K++ R F E + + D G+ P +E TP+ A D E
Sbjct: 259 L---ETGKKDQSKQKESQRK--FEEETVKSKVTVDTGVIP-ASEEKAETPTA-AEDDNEG 311
Query: 350 YDAEIARKL-----QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSL 404
+ +K +E+E + +A A E +A+L EE++ ++ + ++
Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371
Query: 405 DKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 437
+ K+ E + + K K KE + K E
Sbjct: 372 LEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Score = 38.5 bits (88), Expect = 0.014
Identities = 82/400 (20%), Positives = 151/400 (37%), Gaps = 80/400 (20%)
Query: 91 IQEKLAIEAERRRIQEKKDEDIARLLQEKELQE----------EKKRKKHFPE------- 133
+ +K A + ER R +K+DE+ A+L + KE +E +K+ ++ F E
Sbjct: 228 VAQKKAEKKERER--KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285
Query: 134 ------FPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHP 187
PA+ A++ + D G ++ ++ + ++ G+ + +KEK + P
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKKD---------KKKKKGEKEEKEKEKKKGP 336
Query: 188 -----------LENLEEPEQHCSSKRSLS----SSSSGKGRDNPHINNEQHERKRSTQ-E 231
L L+E E+ + K ++ + E+ ERK+ + E
Sbjct: 337 SKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKE 396
Query: 232 RPRR-----PLLPTISGEVFLSTEC-----DDWETKINHQTRNWEKQSRHQDRLSPKSSQ 281
R R LL E E ++ + +K+ ++D+ K Q
Sbjct: 397 RKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQ 456
Query: 282 KAGLHCKEVVYGRDHGQGEHRKRRHRPR---TPPFSESEEQLHLHDAGMKPRVMKEAVST 338
+ L KEV + + P TPP E EE+ DAG+ EA+++
Sbjct: 457 Q--LESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDD---WEAMAS 511
Query: 339 PSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKE 398
+ E+ +EEE + +DEE EE++ +++
Sbjct: 512 DEETEKVEGNKVHIEVKENPEEEE-------EEEEEEEEDEE-----SEEEEEEEGESEG 559
Query: 399 REKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 438
E D++ D + KT SK SD + S ++R
Sbjct: 560 SEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDR 599
Score = 35.8 bits (81), Expect = 0.089
Identities = 58/283 (20%), Positives = 108/283 (38%), Gaps = 30/283 (10%)
Query: 14 VKEVCRDFAVLEDHTLAHSLQEQE----IEHHLASNVQRNRLVQHDLQVAKQLQEED--- 66
VK + A L++ +E+E +E A + RL Q + KQ ++E
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 67 LKAQAQL----QKRYKDLEQQDCEIAQ----EIQEKLAIEAERRRIQEKKDEDIARLLQE 118
LK + +L Q+ + + ++ Q E+ K ++ +R ++KK + I + L+
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 119 KELQEEKK-------RKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQ 171
KE+ E + ++ PE T + ED + G + S
Sbjct: 461 KEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMAS--DEETEKV 518
Query: 172 RDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQE 231
K KE PE E EE E+ S+ +G + + + + K S +
Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKT 578
Query: 232 RPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDR 274
++P S + + DD TK + R ++K R ++
Sbjct: 579 LDKKPSKEMSSDSEY---DSDDDRTK---EERAYDKAKRRIEK 615
Score = 29.3 bits (64), Expect = 8.3
Identities = 23/104 (22%), Positives = 42/104 (40%)
Query: 81 EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAY 140
E + E +E +E+ E+E +E + E +++++ +EK K + P+
Sbjct: 529 ENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMS 588
Query: 141 ADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKP 184
+DS Y D D+ RA + RL+ K P
Sbjct: 589 SDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAP 632
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 52.4 bits (124), Expect = 9e-07
Identities = 55/245 (22%), Positives = 102/245 (41%), Gaps = 14/245 (5%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRI---QEKKDEDIARLLQEKELQEE 124
+ Q+R K+L +QQ+ E + +E++ E ERRR QE K + + Q + LQ +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
Query: 125 KKRKK-------HFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTV 177
K+++ H + Y+Y++G P + A + Q T
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTA 523
Query: 178 KHK-KEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRP 236
E+P L +E S + + +S +NP + + RS+ R
Sbjct: 524 SQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEED 583
Query: 237 LLPTI 241
+ P +
Sbjct: 584 IPPKV 588
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 52.4 bits (124), Expect = 9e-07
Identities = 55/245 (22%), Positives = 102/245 (41%), Gaps = 14/245 (5%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRI---QEKKDEDIARLLQEKELQEE 124
+ Q+R K+L +QQ+ E + +E++ E ERRR QE K + + Q + LQ +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
Query: 125 KKRKK-------HFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTV 177
K+++ H + Y+Y++G P + A + Q T
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTA 523
Query: 178 KHK-KEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRP 236
E+P L +E S + + +S +NP + + RS+ R
Sbjct: 524 SQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEED 583
Query: 237 LLPTI 241
+ P +
Sbjct: 584 IPPKV 588
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/342 (19%), Positives = 133/342 (38%), Gaps = 42/342 (12%)
Query: 58 VAKQLQEEDLKAQAQLQKR--YKDLEQQDCEIA-------QEIQEKLAIEAERRRIQEKK 108
+ K+LQ K QAQ+++ + L QQ E QE +EK+ + E+ R QE+K
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK 317
Query: 109 DEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPC 168
++ EKE + ++ + + + R + + ++ + + +E +
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 377
Query: 169 RLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRS 228
R +++ K + ++EK E + E E+ + K + EQ E+ R
Sbjct: 378 RQEQEAK-MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 229 TQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCK 288
+E+ R + E KI Q +Q K ++ G C+
Sbjct: 437 QEEKIR------------------EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 289 EVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQE 348
+ ++ E + RR + E++ + + K R +E M ++++
Sbjct: 479 QEAKMQEQ---EEKMRRQEEKI-----REQEKKIREQEEKIREQEE------MMQEQEEK 524
Query: 349 WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEK 390
++ E QEE++ + MR + E+ RL EEK
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/370 (17%), Positives = 148/370 (40%), Gaps = 37/370 (10%)
Query: 89 QEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYED 148
+E++EK A E+ ++ E + +I L KEL+ + +R K +A AD E
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQ--LNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 149 GDQPGSRRAR----ELGSGFSRPC--RLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKR 202
+A+ EL + ++ ++ R + ++ ++EK + E + E E+ +
Sbjct: 263 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE 322
Query: 203 SLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQT 262
+ K R + E+ E+ R +E+ ++ E E KI Q
Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE------QEKIREQEEKRQEEEKIREQE 376
Query: 263 RNWEKQS---RHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQ 319
+ E+++ R ++++ + ++ +E++ ++ GE ++ E EE+
Sbjct: 377 KRQEQEAKMWRQEEKI--REQEEKIREQEEMMQEQEEKMGEQEEKMW--------EQEEE 426
Query: 320 LHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDE 379
+ + M R +E + + +E + ++EE + Q Q A+ +
Sbjct: 427 MQEQEEKM--RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 380 EIARLLMAEEKKAYKKAKE--------REKSSLDKRKQDPEWKPKTAKAANSKSKESDEP 431
E + +E+K ++ K+ RE+ + + +++ W+ + + + E
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544
Query: 432 HHSKNERPAR 441
+ E R
Sbjct: 545 KMRRQEEKMR 554
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 51.2 bits (121), Expect = 2e-06
Identities = 77/354 (21%), Positives = 147/354 (41%), Gaps = 48/354 (13%)
Query: 101 RRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRAREL 160
R+ +EKK +D +E++++ ++ + RA + S +++E
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKS----------RSKSKEK 467
Query: 161 GSGFSRPCRLQR-DGKTVKHKKEKPEHPLENLEEPEQHCSSK-------RSLSSSSSGKG 212
R + R + K ++ + + +H EN++E E+ SK RS S +
Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSKGRDH--ENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 213 RDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQ 272
+ N H +++ E+ R Q R R ECD + K ++ +R E+ SR +
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSR---------------ECDITKGKHSYNSRTRER-SRSR 569
Query: 273 DR---LSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPR---TPPFSESEEQLHLHDAG 326
DR + ++ + KE Y R Q R+ R R R TPP +
Sbjct: 570 DRSRRVRSRTHDRDRSRSKE--YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRD 627
Query: 327 MKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLM 386
+ +E+ S ++ +R+QE + + E+ + ++ + E+ A
Sbjct: 628 SRSSEREESQSR-NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQ 686
Query: 387 AEEKKAYKKAKERE-KSSLDKRKQDPEWKPKTAKAANSKSKESDEPH-HSKNER 438
+ K + +++ E KSS+ K K+D + + K N KSK + H H KN++
Sbjct: 687 SPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEK-ENQKSKGQENDHVHEKNKK 739
Score = 47.0 bits (110), Expect = 4e-05
Identities = 78/406 (19%), Positives = 160/406 (39%), Gaps = 52/406 (12%)
Query: 86 EIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYY 145
E+ +EI+ + +A + E + L+ + ++++E+K K+H ++ + +DS
Sbjct: 149 EVVREIENQKT-DAASKPFAEVRILSCGELIPKSKVKKEEK-KRHKSSSSSSSSSSDSDS 206
Query: 146 YEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLS 205
D E + + K+ K KK+ ++ ++ +E ++ SK+S S
Sbjct: 207 SSDSQSSSDSSDSESAT----------EEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSAS 256
Query: 206 SSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNW 265
S S E E + + RP +P I FL + K + + R
Sbjct: 257 SESEA----------ENLEAQPQSTVRPEE--IPPIPENRFLMRKSPP---KADEKERKN 301
Query: 266 EKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDA 325
++ R ++ +P +SQ A + +V G+ + R RTP S S ++ +
Sbjct: 302 RERERERE-CNPPNSQPASYQRRLLV--TRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Query: 326 GMKPRVMKEAVSTPSRM-AHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARL 384
P ++ + RM + W + + + +E + V ++ ++ ++
Sbjct: 359 ---PPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSES 415
Query: 385 LMAEEKKAYK----KAKEREKSSLDKRKQDPEWKPKTAKAA----------NSKSKESDE 430
+ +K K K+ +E+ ++D ++K K K A SKSKE D
Sbjct: 416 PNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS 475
Query: 431 PHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK 476
H+ E+ R + G D + +QS ++ + S K
Sbjct: 476 KHNRNEEKRMRS----RSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/415 (16%), Positives = 166/415 (40%), Gaps = 34/415 (8%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
+++E+ ++R + + + + QEE + + + +R +++ + E +E++E
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPG 153
K+ + + R +EK+ E+ EK ++EK++++ A + E+ +
Sbjct: 399 KMHEQEKIREQEEKRQEE------EKIREQEKRQEQE----------AKMWRQEEKIREQ 442
Query: 154 SRRARELGSGFSRPCRLQRDGKTVKHKKEKPE-----HPLENLEEPEQHCSSKRSLSSSS 208
+ RE R + + ++ ++++ E E + E E+ K +
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 209 SGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDW--ETKINHQTRNWE 266
K R Q E+ R +E+ R E + + + W E K++ Q + WE
Sbjct: 503 E-KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
Query: 267 KQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSES----EEQLHL 322
++ R + ++ +E V+ ++ E ++R + + E++ +
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 323 HDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIA 382
+ K R +E + M +E + + ++EE + Q + Q+E+I
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE---TMWRQEEKIR 678
Query: 383 RLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 437
E+K ++ K RE+ + + +++ W+ + + + E + E
Sbjct: 679 E---QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 50.4 bits (119), Expect = 3e-06
Identities = 64/370 (17%), Positives = 149/370 (40%), Gaps = 32/370 (8%)
Query: 53 QHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDI 112
+ ++ ++ E K + Q +KR ++ + ++ E QE + K+ + E+ R QE+K +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE- 448
Query: 113 ARLLQEKEL--QEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRL 170
QEK++ QEEK ++ R + + ++ + E + + ++
Sbjct: 449 ----QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE------EKIHEQEEIWRQKEKM 498
Query: 171 QRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQ---HERKR 227
+ ++ ++EK E + E E+ + K R+ + E+ HE+++
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 228 STQERPRRPLLPTISGEVFLSTECDDW--ETKINHQTRN-WEKQSRHQDRLSPKSSQKAG 284
+E R+ E W E KI Q W ++ + +++ + Q+
Sbjct: 559 IWEEEKRQ------------EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 285 LHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAH 344
+ +E + + ++ + R + E EE + M + K
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 345 RDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSL 404
+ W E R+ QE+++ + +R + E+ ++ EEK ++ K +E+
Sbjct: 667 EETMWRQEEKIRE-QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Query: 405 DKRKQDPEWK 414
+R+++ W+
Sbjct: 726 MRRQEEKMWE 735
Score = 45.4 bits (106), Expect = 1e-04
Identities = 70/408 (17%), Positives = 158/408 (38%), Gaps = 40/408 (9%)
Query: 36 QEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKL 95
Q + L + V+ N L Q QEE + Q + + +++ Q+ E +E +EK+
Sbjct: 275 QSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 96 AIEAER-RRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGS 154
+ E+ RR +E E ++ +++E+ EK+ K E E+
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
Query: 155 RRARELGSGFSRPCRL------QRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSS 208
+ REL ++ +++ + ++ ++++ E + + E+ + +
Sbjct: 391 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 209 SGKGRDNPHINNEQ---HERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNW 265
R I+ ++ E KR QE R E KI+ Q W
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ------------------EEKIHEQEEIW 492
Query: 266 -EKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHD 324
+K+ H+ + ++ +E + ++ E ++ R + EQ +
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE----EKIREQEEMWR 548
Query: 325 AGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARL 384
K ++ R D+ W E R+ QEE++ + +R + + E+ ++
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE-QEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 385 LMAEEK--KAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDE 430
EEK + +K +E+E+ ++ ++ E + T + ++ ++
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 43.5 bits (101), Expect = 4e-04
Identities = 73/368 (19%), Positives = 145/368 (39%), Gaps = 27/368 (7%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQK-RYKDLEQQDCEIAQEI 91
L+E+ E + R + ++ ++ QE++ K Q +K R ++ + ++ E
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 92 QEKLAIEAERRRIQEKKDEDIARLLQEKELQEEK-----KRKKHFPEFPATRAYADSYYY 146
QE+ E E+ R +EK+ E QE+++ E++ K K H E + +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 147 EDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSS 206
E+ + + RE R R+ + + ++EK H E + E E+ + +
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM-HEQEKIWEEEKRQEQEDKMWR 574
Query: 207 SSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQT---R 263
K R+ Q E+ R +E+ + E + + E KI Q R
Sbjct: 575 QEE-KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ----EEKIQEQEEKIR 629
Query: 264 NWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLH 323
E++ R Q+ ++ + +K G ++ E ++ + + E+ +
Sbjct: 630 EQEEKIREQEEMTQEQEEKMG--------EQEEKMCEQEEKMQEQEETMWRQEEK---IR 678
Query: 324 DAGMKPRVMKEAVSTPSRMAHRDQE-WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIA 382
+ K R +E + M +E ++ E QEE++ + MR + E+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 383 RLLMAEEK 390
RL EEK
Sbjct: 739 RLRQQEEK 746
Score = 30.8 bits (68), Expect = 2.9
Identities = 18/71 (25%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 63 QEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKEL- 121
QE+ ++ Q + + +++ Q+ E E +EK+ + E+ + QE+K + E+E+
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Query: 122 --QEEKKRKKH 130
Q+E+K ++H
Sbjct: 740 LRQQEEKMQEH 750
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 49.7 bits (117), Expect = 6e-06
Identities = 74/411 (18%), Positives = 162/411 (39%), Gaps = 54/411 (13%)
Query: 36 QEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKL 95
Q + L + V+ N L Q QEE + Q + + +++ Q+ E +E +EK+
Sbjct: 275 QSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 96 AIEAERRRIQEK----KDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQ 151
+ E+ R QE+ K+E + R QE+ + E++++ + E + E +
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRR--QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
Query: 152 PGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGK 211
R +E +++ + ++ ++++ E + + E+ + +
Sbjct: 389 QEKIREQE---------EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 212 GRDNPHINNEQ---HERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNW-EK 267
R I+ ++ E KR QE R E KI Q W +K
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQ------------------EEKIREQEEIWRQK 481
Query: 268 QSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGM 327
+ H+ K +K +E ++ ++ E ++ R + E EE++
Sbjct: 482 EKMHEQEKIRKQEEKVWRQ-EEKMHDQEEKIREQEEKMWR-QEEKIREQEEKI------- 532
Query: 328 KPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMA 387
R +E + M ++QE E K+QE+E + Q + Q + E +
Sbjct: 533 --REQEEKIREQEEMM-QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589
Query: 388 EEKKAYKKAKE-REKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 437
+E+K +++ ++ RE+ + + +++ W+ + + + E + E
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Score = 44.3 bits (103), Expect = 2e-04
Identities = 75/405 (18%), Positives = 161/405 (39%), Gaps = 17/405 (4%)
Query: 42 LASNVQRNRLVQHDLQVAKQLQEEDLKA----QAQLQKRYKDLEQQDCEIAQEIQEKLAI 97
L+ + RN + +L+ +E L+ ++++Q K+L+++ E A+ + + +
Sbjct: 205 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLPQQQL 263
Query: 98 EAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRA 157
+AE + ++ A+L + E E R E R +E+ Q +
Sbjct: 264 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323
Query: 158 RELGSGF-SRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNP 216
RE + +++R + + K+EK E + E E+ + K R+
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRE-- 381
Query: 217 HINNEQHERKRSTQERPRRPLLPTI-SGEVFLSTECDDWETKINHQTRNWEKQSRHQDRL 275
+ + HE+++ ++ +R I E E W + + R E++ R Q++
Sbjct: 382 -LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE--EKIREQEEKIREQEKK 438
Query: 276 SPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEA 335
+ +K +H +E + + Q + R + E Q K R +E
Sbjct: 439 MWRQEEK--IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK 496
Query: 336 VSTPSRMAHRDQEWYDAEIARKL--QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAY 393
V H DQE E K+ QEE++ + +R + E+ + EEK
Sbjct: 497 VWRQEEKMH-DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Query: 394 KKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 438
++ K +E+ + ++++ + + + K +E +E + E+
Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Score = 42.0 bits (97), Expect = 0.001
Identities = 69/401 (17%), Positives = 165/401 (41%), Gaps = 65/401 (16%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
QE++I ++R + + + + QEE + + + +R +++ + E +E++E
Sbjct: 326 QEEKIREQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPG 153
K+ + + R +EK+ E E++++E++KR++ A + E+ +
Sbjct: 385 KMHEQEKIREQEEKRQE-------EEKIREQEKRQEQ---------EAKMWRQEEKIREQ 428
Query: 154 SRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGR 213
+ RE + ++ R + + H++EK + E+ E ++ + +
Sbjct: 429 EEKIRE------QEKKMWRQEEKI-HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 214 DNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQD 273
+ H + E+ R +E+ R + D E KI Q EK R ++
Sbjct: 482 EKMH----EQEKIRKQEEKVWRQ-----------EEKMHDQEEKIREQE---EKMWRQEE 523
Query: 274 RLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMK 333
++ + ++ +E + ++ E ++ E EE++ + K R +
Sbjct: 524 KI--REQEEKIREQEEKIREQEEMMQEQEEK--------MGEQEEKMQEQE---KMRRQE 570
Query: 334 EAVSTPSRMAHRDQEWYDAEIARKL--QEEELLATQVDMRAAQVAQDEEIARLLMAEEKK 391
E + R+QE E K+ QEE++ + +R + E+ ++ EEK
Sbjct: 571 EKI--------REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 392 AYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPH 432
++ K +E+ +R+++ W+ + + + + H
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
Score = 30.8 bits (68), Expect = 2.9
Identities = 24/100 (24%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQ 92
+ EQE V R HD + + QEE + Q + + ++ ++ E +E +
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 93 EKLAIEAERRRIQEKKDEDIARLLQEKEL---QEEKKRKK 129
E + + E+ QE+K ++ ++ +++E QEEK R++
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 49.7 bits (117), Expect = 6e-06
Identities = 70/394 (17%), Positives = 155/394 (39%), Gaps = 24/394 (6%)
Query: 58 VAKQLQEEDLKAQAQLQKR--YKDLEQQDCEIA-------QEIQEKLAIEAERRRIQEKK 108
+ K+LQ K QAQ+++ + L QQ E QE +EK+ + E+ R QE+K
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 390
Query: 109 -DEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRP 167
E ++ +++E+ EK+ K E E+ + REL
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 168 CRLQ------RDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNE 221
+++ ++ + ++ ++++ E + + E+ + + R I
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI--- 507
Query: 222 QHERKRSTQERPRRPLLPTISGEVFLSTECDDW--ETKINHQTRNWEKQSRHQDRLSPKS 279
HE+++ +E R+ E + + + W + KI+ Q KQ R K
Sbjct: 508 -HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 280 -SQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVST 338
Q+ + +E R + ++ + R + E EE + M + K
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC-EQ 625
Query: 339 PSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKE 398
+M ++++ E + QE+++ + +R + E+ ++ EEK ++ K
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685
Query: 399 REKSSLDKRKQDPEWKPKTAKAANSKSKESDEPH 432
+E+ +R+++ W+ + + + + H
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719
Score = 43.1 bits (100), Expect = 6e-04
Identities = 69/365 (18%), Positives = 151/365 (41%), Gaps = 34/365 (9%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
QE++I+ ++ ++ + ++ QEE ++ Q ++ ++ ++ E+ E +E
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKIRE-QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 94 KLAIEAER--------RRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYY 145
K+ + E R ++EK E QE++ QEE+K ++ + A +
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE---QEKRQEQEAKMWR 481
Query: 146 YEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLS 205
E+ + + RE + ++ R + + H++EK + E+ E ++
Sbjct: 482 QEEKIREQEEKIRE------QEEKMWRQEEKI-HEQEKIREEEKRQEQEEMWRQEEKIRE 534
Query: 206 SSSSGKGRDNPHINNEQHERKRSTQERP-RRPLLPTISGEVFLSTECDDW--ETKINHQ- 261
+ ++ H EQ E+ R +E+ R+ E E W E KI Q
Sbjct: 535 QEEIWRQKEKIH---EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 262 --TRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRH-----RPRTPPFS 314
R E++ R Q+ ++ + +K G +++ + Q + K R R +
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 315 ESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQ 374
E EE++ + M+ + K +M ++++ + E + QEE++ +V +R +
Sbjct: 652 EQEEKIREQEEMMQEQEEK-MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Query: 375 VAQDE 379
E
Sbjct: 711 EKMQE 715
Score = 35.4 bits (80), Expect = 0.12
Identities = 48/269 (17%), Positives = 102/269 (37%), Gaps = 44/269 (16%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQ-----LQEEDLKAQAQLQKRYKDLEQQDCEIA 88
QE+ E Q ++ + + ++ +Q QEE + Q ++++ K EQ++
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM--- 525
Query: 89 QEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYED 148
+EK+ + E R +EK E ++ +++E ++ K H E + E+
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 149 GDQPGSRRARE------------------LGSGFSRPC----RLQRDGKTVKHKKEKPEH 186
+ + RE +G + C ++Q + ++ ++EK
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 187 PLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVF 246
+ + E E+ + + K + EQ E+ + +E+ RR
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR----------- 694
Query: 247 LSTECDDWETKINHQTRNWEKQSRHQDRL 275
E WE ++ + + EK HQ+ L
Sbjct: 695 --QEEKMWEQEVRLRQQE-EKMQEHQEHL 720
Score = 32.3 bits (72), Expect = 0.98
Identities = 27/98 (27%), Positives = 56/98 (57%), Gaps = 12/98 (12%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQ---LQEEDLKAQAQLQKRYKDLEQQDCEIAQ 89
+QEQE + Q ++ + + ++ +Q ++E++ Q Q +K ++ E++ CE +
Sbjct: 629 MQEQEEKMRR----QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEE 683
Query: 90 EIQEKLAIEAERRRIQEKKDEDIARLLQEKE-LQEEKK 126
++QE+ E + RR +EK E RL Q++E +QE ++
Sbjct: 684 KMQEQ---EEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 49.7 bits (117), Expect = 6e-06
Identities = 60/230 (26%), Positives = 102/230 (44%), Gaps = 25/230 (10%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHP 187
++ E Y E R+A L R + +RD + + + P
Sbjct: 463 QQLLHEQALLLEYKRKQLEE------QRQAERL----QRQLKQERDYLVSLQHQRQEQRP 512
Query: 188 LENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKR-STQERPRRP 236
+E ++P H K +S S + P E ER R + Q P P
Sbjct: 513 VE--KKPLYH--YKEGMSPS------EKPAWAKEVEERSRLNRQSSPAMP 552
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 49.7 bits (117), Expect = 6e-06
Identities = 60/230 (26%), Positives = 102/230 (44%), Gaps = 25/230 (10%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHP 187
++ E Y E R+A L R + +RD + + + P
Sbjct: 463 QQLLHEQALLLEYKRKQLEE------QRQAERL----QRQLKQERDYLVSLQHQRQEQRP 512
Query: 188 LENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKR-STQERPRRP 236
+E ++P H K +S S + P E ER R + Q P P
Sbjct: 513 VE--KKPLYH--YKEGMSPS------EKPAWAKEVEERSRLNRQSSPAMP 552
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 49.7 bits (117), Expect = 6e-06
Identities = 89/430 (20%), Positives = 177/430 (41%), Gaps = 35/430 (8%)
Query: 20 DFAVLEDHTLAHSLQEQEIEHH---LASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKR 76
D V ED + S + ++E L ++++ + V+ DL+ AK+ E DLK Q+
Sbjct: 1011 DLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL---TQES 1067
Query: 77 YKDLEQQDCEIAQEIQEK-LAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHF-PEF 134
DLE ++ +++++K I + +I+ DE + L +K+L+E + R + E
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQNSKIE---DEQVLALQLQKKLKENQARIEELEEEL 1124
Query: 135 PATRAYADSYYYEDGD-----QPGSRRARELGSGFSRPCRL--QRDGKTVKHKKEKPEHP 187
A R D + S R E G S + +R+ + K +++ E
Sbjct: 1125 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1184
Query: 188 LENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFL 247
L++ E K + S + G+ DN ++ E+++S + + + +
Sbjct: 1185 LQH-EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKA 1243
Query: 248 STECDDWETKINHQTRNWE-KQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRH 306
+ + Q + K Q L+ ++Q+A L + R + E +
Sbjct: 1244 KANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
Query: 307 RPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQE-WYDAEIARKLQEEELLA 365
+++ E L R ++E + +AH Q +D ++ R+ EEE A
Sbjct: 1304 TRGKLSYTQQMEDL--------KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEA 1355
Query: 366 TQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKERE--KSSLDKRKQDPEWKPKTAKAANS 423
+ +++ + E+A+ E A ++ +E E K L +R QD E + +A N+
Sbjct: 1356 -KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE---EAVEAVNA 1411
Query: 424 KSKESDEPHH 433
K ++ H
Sbjct: 1412 KCSSLEKTKH 1421
Score = 40.8 bits (94), Expect = 0.003
Identities = 79/406 (19%), Positives = 163/406 (40%), Gaps = 29/406 (7%)
Query: 47 QRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQE 106
Q+N ++ + +A QLQ++ + QA++++ ++LE + A+ + + + E I E
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 107 KKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRR-----ARELG 161
+ +E A +++ KKR+ F + R ++ + R+ ELG
Sbjct: 1151 RLEE--AGGATSVQIEMNKKREAEFQKM--RRDLEEATLQHEATAAALRKKHADSVAELG 1206
Query: 162 SGFSRPCRLQRDGKTVKHKKEKPEHPLE---NLEEPEQHCSSKRSLSSSSSGKGRDNPHI 218
R+++ K +KEK E LE EQ +K +L S
Sbjct: 1207 EQIDNLQRVKQ-----KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 219 NNEQHERKRSTQE-RPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSP 277
+ E +RS + +R L T +GE L+ + ++ E I+ TR ++ + L
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGE--LARQLEEKEALISQLTRGKLSYTQQMEDLK- 1318
Query: 278 KSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVS 337
+ ++ G + + + + R + +++E Q L A + +
Sbjct: 1319 RQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1378
Query: 338 TPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQ-----DEEIARLLM-AEEKK 391
T + + E ++A++LQ+ E V+ + + + + EI L++ E
Sbjct: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Query: 392 AYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 437
A A ++++ + DK EWK K ++ + E E
Sbjct: 1439 AAAAALDKKQRNFDKIL--AEWKQKYEESQSELESSQKEARSLSTE 1482
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 7/102 (6%)
Query: 36 QEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE-K 94
+E HL + + N+ +Q ++ + E K +L+K K LE + E+ ++E +
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAE 1550
Query: 95 LAIEAERRRIQEKKDE------DIARLLQEKELQEEKKRKKH 130
++E E +I + E +I R L EK+ + E+ ++ H
Sbjct: 1551 ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH 1592
Score = 31.6 bits (70), Expect = 1.7
Identities = 27/125 (21%), Positives = 59/125 (47%), Gaps = 16/125 (12%)
Query: 3 EVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQL 62
+V +Q L +E C D + + +Q + A + N ++ + ++ +L
Sbjct: 892 QVQAEQDNLNDAEERC-------DQLIKNKIQLE------AKVKEMNERLEDEEEMNAEL 938
Query: 63 QEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKK---DEDIARLLQEK 119
+ K + + + KD++ + +A+ +EK A E + + + E+ DE IA+L +EK
Sbjct: 939 TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK 998
Query: 120 ELQEE 124
+ +E
Sbjct: 999 KALQE 1003
Score = 30.4 bits (67), Expect = 3.7
Identities = 35/137 (25%), Positives = 69/137 (50%), Gaps = 16/137 (11%)
Query: 8 QSKLPGVKEVCRDF------AVLEDHTLAHSLQ-EQEIEHHLA---SNVQRN-RLVQHDL 56
QS++ + CR+ A+ + +A L+ EQ+ HL N+++ + +QH L
Sbjct: 1740 QSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1799
Query: 57 QVAKQLQEEDLKAQAQ-LQKRYKDLEQQ-DCEIAQEIQEKLAIEAERRRIQE---KKDED 111
A+Q+ + K Q Q L+ R ++LE + + E + + + RRI+E + +ED
Sbjct: 1800 DEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEED 1859
Query: 112 IARLLQEKELQEEKKRK 128
LL+ ++L ++ + K
Sbjct: 1860 KKNLLRLQDLVDKLQLK 1876
Score = 29.3 bits (64), Expect = 8.3
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
Query: 22 AVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLE 81
AV+E + L EQE+ + VQ L K+ E DL QLQ ++
Sbjct: 1692 AVVEQTERSRKLAEQELIE-TSERVQLLHSQNTSLINQKKKMESDL---TQLQSEVEEAV 1747
Query: 82 QQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQ--EKELQEEKKRKKH 130
Q+ C A+E +K +A + KK++D + L+ +K +++ K +H
Sbjct: 1748 QE-CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1797
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 49.7 bits (117), Expect = 6e-06
Identities = 89/415 (21%), Positives = 164/415 (39%), Gaps = 47/415 (11%)
Query: 25 EDHTLAHSLQ--EQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ 82
E+H L+ ++ + ++E SN L + ++ +QLQ + +A ++ KDLEQ
Sbjct: 502 ENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQ 561
Query: 83 QDCEIAQ---EIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRA 139
+ + + ++E+ + +E R +K+ + E K EF +
Sbjct: 562 EKDHLNRAMWSLRERSQVSSEARMKDVEKENKALH-----QTVTEANGKLSQLEFEKRQL 616
Query: 140 YADSYYYEDGDQPGSRRARELGSGFSRPCRLQR---DGKTVKHKKEKPEHPLENLE---- 192
+ D ++ + + REL RL R +T K E EH + L+
Sbjct: 617 HRDLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENR 676
Query: 193 EPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
+ + +++S G RDN ++ E E +R L+ T+ F ST+
Sbjct: 677 TLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRR---------LVETMR---FTSTKLA 724
Query: 253 DWETKINHQTRNWEKQSRHQDRLSP--KSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRT 310
E + R E+ ++ D L K S++ L + V Q H+ +T
Sbjct: 725 QMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQT 784
Query: 311 PPFSESE------------EQLHLHDAGMK-PRVMKEAVSTPSRMAHRDQEWYDAEIARK 357
E E L L +A ++ ++A+ +D++ + E R
Sbjct: 785 LESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRL 844
Query: 358 LQEEELLATQVDMRAAQVAQDEEIARLL---MAEEKKAYKKAKEREKSSLDKRKQ 409
Q+ EL +D A+++ E+ +R L +A + A K KE EK + D KQ
Sbjct: 845 WQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQ 899
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 48.9 bits (115), Expect = 1e-05
Identities = 85/414 (20%), Positives = 170/414 (41%), Gaps = 37/414 (8%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEK 94
EQ+++ L ++++ + V+ DL+ AK+ E DLK Q+ DLE ++ + +++K
Sbjct: 1028 EQQVDD-LEGSLEQEKKVRMDLERAKRKLEGDLKL---TQESIMDLENDKQQLDERLKKK 1083
Query: 95 --------LAIEAER---RRIQEKKDEDIARLLQ-EKELQEEKKRKKHFPEFPATRAYAD 142
IE E+ ++Q+K E AR+ + E+EL+ E+ + + + +
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 143 SYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKR 202
E ++ G + ++ R Q+ + ++ + E L ++H S
Sbjct: 1144 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR--KKHADSVA 1201
Query: 203 SLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQT 262
L R + E+ E K + + I + L C E ++N
Sbjct: 1202 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-MEQIIKAKANLEKMCRTLEDQMNEHR 1260
Query: 263 RNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHL 322
E+ R + L +SQ+A L + R + E + +++ E L
Sbjct: 1261 SKAEETQRSVNDL---TSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDL-- 1315
Query: 323 HDAGMKPRVMKEAVSTPSRMAHRDQE-WYDAEIARKLQEEELLATQVDMRAAQVAQDEEI 381
R ++E V + +AH Q +D ++ R+ EEE A + +++ + E+
Sbjct: 1316 ------KRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEA-KAELQRVLSKANSEV 1368
Query: 382 ARLLMAEEKKAYKKAKERE--KSSLDKRKQDPEWKPKTAKAANSKSKESDEPHH 433
A+ E A ++ +E E K L +R Q+ E + +A N+K ++ H
Sbjct: 1369 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE---EAVEAVNAKCSSLEKTKH 1419
Score = 45.1 bits (105), Expect = 1e-04
Identities = 84/400 (21%), Positives = 158/400 (39%), Gaps = 40/400 (10%)
Query: 64 EEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQE-KELQ 122
E++ +QLQK+ K+L+ + +E++E+L E R EK D++R L+E E
Sbjct: 1095 EDEQALGSQLQKKLKELQAR----IEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 123 EE---------KKRKKHFPEFPATRAYADSYYYEDGDQPGSRRAR------ELGSGFSRP 167
EE + KK EF R + + + R + ELG
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 168 CRLQRDGKTVKHKKEKPEHPLE---NLEEPEQHCSSKRSLSS-SSSGKGRDNPHINNEQH 223
R+++ K +KEK E LE EQ +K +L + + + N H + +
Sbjct: 1211 QRVKQ-----KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEE 1265
Query: 224 ERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKA 283
++ +R L T +GE LS + D+ E I+ TR ++ + L + ++
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGE--LSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEV 1323
Query: 284 GLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMA 343
+ + + + R + +++E Q L A + + T +
Sbjct: 1324 KAK-NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 344 HRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQ-----DEEIARLLM-AEEKKAYKKAK 397
+ E ++A++LQE E V+ + + + + EI L++ E A A
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 398 EREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 437
++++ + DK EWK K ++ + E E
Sbjct: 1443 DKKQRNFDKIL--AEWKQKYEESQSELESSQKEARSLSTE 1480
Score = 31.6 bits (70), Expect = 1.7
Identities = 36/143 (25%), Positives = 73/143 (51%), Gaps = 16/143 (11%)
Query: 2 AEVSIDQSKLPGVKEVCRDF------AVLEDHTLAHSLQ-EQEIEHHLA---SNVQRN-R 50
A++S Q+++ + CR+ A+ + +A L+ EQ+ HL N+++ +
Sbjct: 1732 ADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK 1791
Query: 51 LVQHDLQVAKQLQEEDLKAQAQ-LQKRYKDLEQQ-DCEIAQEIQEKLAIEAERRRIQE-- 106
+QH L A+Q+ + K Q Q L+ R ++LE + + E + + + RRI+E
Sbjct: 1792 DLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELT 1851
Query: 107 -KKDEDIARLLQEKELQEEKKRK 128
+ +ED LL+ ++L ++ + K
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLK 1874
Score = 31.2 bits (69), Expect = 2.2
Identities = 24/102 (23%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Query: 36 QEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE-K 94
+E HL + + N+ +Q ++ + K +L+K K LE + E+ ++E +
Sbjct: 1489 EESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAE 1548
Query: 95 LAIEAERRRIQEKKDE------DIARLLQEKELQEEKKRKKH 130
++E E +I + E +I R L EK+ + E+ ++ H
Sbjct: 1549 ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH 1590
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 48.9 bits (115), Expect = 1e-05
Identities = 53/211 (25%), Positives = 95/211 (45%), Gaps = 17/211 (8%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHP 187
++ E Y E R+A L R + +RD + + + P
Sbjct: 463 QQLLHEQALLLEYKRKQLEE------QRQAERL----QRQLKQERDYLVSLQHQRQEQRP 512
Query: 188 LENLEEPEQHCSSKRSLSSSSSGKGRDNPHI 218
+E ++P H S S ++ PH+
Sbjct: 513 VE--KKPLYHYKEGMS-PSEKPAWAKEIPHL 540
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 48.9 bits (115), Expect = 1e-05
Identities = 53/211 (25%), Positives = 95/211 (45%), Gaps = 17/211 (8%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHP 187
++ E Y E R+A L R + +RD + + + P
Sbjct: 463 QQLLHEQALLLEYKRKQLEE------QRQAERL----QRQLKQERDYLVSLQHQRQEQRP 512
Query: 188 LENLEEPEQHCSSKRSLSSSSSGKGRDNPHI 218
+E ++P H S S ++ PH+
Sbjct: 513 VE--KKPLYHYKEGMS-PSEKPAWAKEIPHL 540
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 48.9 bits (115), Expect = 1e-05
Identities = 41/160 (25%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRI---QEKKDEDIARLLQEKELQEE 124
+ Q+R K+L +QQ+ E + +E++ E ERRR QE K + + Q + LQ +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
Query: 125 KKRKK-------HFPEFPATRAYADSYYYEDGDQPGSRRA 157
K+++ H + Y+Y++G P + A
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPA 503
Score = 38.1 bits (87), Expect = 0.018
Identities = 42/184 (22%), Positives = 83/184 (45%), Gaps = 20/184 (10%)
Query: 56 LQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARL 115
LQ+A + + E L+ Q QL+++ ++ E+ ++ E Q+++ + E+RR E++
Sbjct: 357 LQLANKERSEALRRQ-QLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR----- 410
Query: 116 LQEKEL--QEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRD 173
+EKEL Q+E+++++H+ E +E + + R + +RD
Sbjct: 411 -REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERD 469
Query: 174 GKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKR-STQER 232
+ + + P+E ++P H K +S S + P E ER R + Q
Sbjct: 470 YLVSLQHQRQEQRPVE--KKPLYH--YKEGMSPS------EKPAWAKEVEERSRLNRQSS 519
Query: 233 PRRP 236
P P
Sbjct: 520 PAMP 523
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 48.9 bits (115), Expect = 1e-05
Identities = 41/160 (25%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRI---QEKKDEDIARLLQEKELQEE 124
+ Q+R K+L +QQ+ E + +E++ E ERRR QE K + + Q + LQ +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
Query: 125 KKRKK-------HFPEFPATRAYADSYYYEDGDQPGSRRA 157
K+++ H + Y+Y++G P + A
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPA 503
Score = 38.1 bits (87), Expect = 0.018
Identities = 42/184 (22%), Positives = 83/184 (45%), Gaps = 20/184 (10%)
Query: 56 LQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARL 115
LQ+A + + E L+ Q QL+++ ++ E+ ++ E Q+++ + E+RR E++
Sbjct: 357 LQLANKERSEALRRQ-QLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR----- 410
Query: 116 LQEKEL--QEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRD 173
+EKEL Q+E+++++H+ E +E + + R + +RD
Sbjct: 411 -REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERD 469
Query: 174 GKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKR-STQER 232
+ + + P+E ++P H K +S S + P E ER R + Q
Sbjct: 470 YLVSLQHQRQEQRPVE--KKPLYH--YKEGMSPS------EKPAWAKEVEERSRLNRQSS 519
Query: 233 PRRP 236
P P
Sbjct: 520 PAMP 523
Score = 37.0 bits (84), Expect = 0.040
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 294 RDHGQGEHRKRRHRPRTP-PFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDA 352
+DH +KR + T +S SEE+ +D+G ++ + P R +++
Sbjct: 303 KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSIL----NLPGESTLR-RDFLRL 357
Query: 353 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 412
++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++++++ E
Sbjct: 358 QLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 413 WKPKTAKAANSKSKESDEPHHSKNE 437
+ K +E ++ H + +
Sbjct: 415 LR---------KQQEREQRRHYEEQ 430
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 48.9 bits (115), Expect = 1e-05
Identities = 77/394 (19%), Positives = 160/394 (40%), Gaps = 69/394 (17%)
Query: 37 EIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLE-QQDCEIAQEIQEKL 95
E+E + +++ R Q L ++ ++E + + Q Q+R + LE ++ E +E++ +
Sbjct: 364 ELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423
Query: 96 AIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSR 155
E ERR+ E+++ L ++++L+ E+ R++ ++
Sbjct: 424 --EEERRKEIERREAAKRELERQRQLEWERNRRQELL---------------------NQ 460
Query: 156 RARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSK------------RS 203
R +E Q D +K KK+ E LE L + + K +
Sbjct: 461 RNKE-----------QEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQE 509
Query: 204 LSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTR 263
+ S++ + I + Q + + S Q R L+P + +N Q +
Sbjct: 510 IESTNKSRELRIAEITHLQQQLQESQQMLGR--LIPE--------------KQILNDQLK 553
Query: 264 NWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQL-HL 322
++ S H+D L + K L KE+ Q + ++ R + QL L
Sbjct: 554 QVQQNSLHRDSL---VTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKEL 610
Query: 323 HDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQ--DEE 380
+ K ++ K+ R+ ++QE E+ ++ +E + A + D + + Q DE
Sbjct: 611 REIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEH 670
Query: 381 IARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWK 414
+ EE+K ++ ++K +K KQ+ + K
Sbjct: 671 QRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDK 704
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 48.9 bits (115), Expect = 1e-05
Identities = 77/394 (19%), Positives = 160/394 (40%), Gaps = 69/394 (17%)
Query: 37 EIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLE-QQDCEIAQEIQEKL 95
E+E + +++ R Q L ++ ++E + + Q Q+R + LE ++ E +E++ +
Sbjct: 364 ELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423
Query: 96 AIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSR 155
E ERR+ E+++ L ++++L+ E+ R++ ++
Sbjct: 424 --EEERRKEIERREAAKRELERQRQLEWERNRRQELL---------------------NQ 460
Query: 156 RARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSK------------RS 203
R +E Q D +K KK+ E LE L + + K +
Sbjct: 461 RNKE-----------QEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQE 509
Query: 204 LSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTR 263
+ S++ + I + Q + + S Q R L+P + +N Q +
Sbjct: 510 IESTNKSRELRIAEITHLQQQLQESQQMLGR--LIPE--------------KQILNDQLK 553
Query: 264 NWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQL-HL 322
++ S H+D L + K L KE+ Q + ++ R + QL L
Sbjct: 554 QVQQNSLHRDSL---VTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKEL 610
Query: 323 HDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQ--DEE 380
+ K ++ K+ R+ ++QE E+ ++ +E + A + D + + Q DE
Sbjct: 611 REIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEH 670
Query: 381 IARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWK 414
+ EE+K ++ ++K +K KQ+ + K
Sbjct: 671 QRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDK 704
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 48.9 bits (115), Expect = 1e-05
Identities = 87/433 (20%), Positives = 171/433 (39%), Gaps = 78/433 (18%)
Query: 43 ASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERR 102
A + + Q LQ ++L +E L+ Q Q +K DL++Q + +++E+++ E
Sbjct: 1982 AMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIE-- 2039
Query: 103 RIQEKKDEDIARLLQEKELQEEK--KRKKHFPEFPATRAYADSYYYEDGDQPGSRRAREL 160
++++K+ ++ L Q+ + E++ K +K E R + + ++
Sbjct: 2040 -LEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ---------- 2088
Query: 161 GSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSS----SSSGKGRDNP 216
+L++ K V + EH +E+ H K S S RD
Sbjct: 2089 --------KLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 2140
Query: 217 HINNEQHERKRSTQERPRRPLL------------PTISGEVFLSTECDDWETKINHQTRN 264
N E + + +E + L+ P +S EV L E D + K T
Sbjct: 2141 ERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNL 2200
Query: 265 WEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHD 324
E+ + ++ L K+ + LH Q E +K+ R E E +L D
Sbjct: 2201 EEQLEQFREELENKNEEVQQLHM----------QLEIQKKESTTRLQEL-EQENKLFKDD 2249
Query: 325 AGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQD------ 378
+KE+ M+ +DQ + A+ +QE+E+ Q++ + ++ Q
Sbjct: 2250 MEKLGLAIKES----DAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTD 2305
Query: 379 ----EEIARLL---------MAEEKKAYKKAKEREKSSLDK-----RKQDPEWKPKTAKA 420
EE L+ + +++ K+ +E E L++ +++ KT+
Sbjct: 2306 NKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMN 2365
Query: 421 ANSKSKESDEPHH 433
A+S S+E+D H
Sbjct: 2366 AHSLSEEADSLKH 2378
Score = 36.2 bits (82), Expect = 0.068
Identities = 19/92 (20%), Positives = 54/92 (58%), Gaps = 1/92 (1%)
Query: 37 EIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLA 96
E E + ++Q + ++ D QV ++ + + +A + QK+ +L+ + ++ ++++EK
Sbjct: 3357 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQ 3416
Query: 97 IEAERRRIQEKKDEDIARLLQEKELQEEKKRK 128
+ + ++ ++ + I + Q++EL+ E+KR+
Sbjct: 3417 -QVYKLDLEGQRLQGIMQEFQKQELEREEKRE 3447
Score = 33.1 bits (74), Expect = 0.58
Identities = 35/113 (30%), Positives = 52/113 (46%), Gaps = 21/113 (18%)
Query: 19 RDFAVLEDHT-LAHSLQEQ----EIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQL 73
+D VL+ T L HS +E E+E A +V + + A++LQEE L + +
Sbjct: 2659 QDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNM 2718
Query: 74 QKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKK 126
KDL Q +++ LA E+ I EK+D E E+QE KK
Sbjct: 2719 TSLQKDLSQ--------VRDHLAEAKEKLSILEKED--------ETEVQESKK 2755
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 48.9 bits (115), Expect = 1e-05
Identities = 93/424 (21%), Positives = 170/424 (40%), Gaps = 44/424 (10%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLE-QQ 83
E+H L+E E E + R + + ++L+ LKA L+ R + E Q
Sbjct: 1598 EEHVAVAQLRE-EAERRAQQQAEAERARE---EAERELERWQLKANEALRLRLQAEEVAQ 1653
Query: 84 DCEIAQEIQEKLAIEAERRRIQEKKDEDIA---RLLQEKELQEEKK------RKKHFPEF 134
+AQ EK EAER + K E+ A R L E+EL+++++ +++ E
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1713
Query: 135 PATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLE-E 193
R A++ E G+Q EL RLQR+ K+++ E L + E
Sbjct: 1714 ELIRLRAET---EQGEQQRQLLEEELA-------RLQREAAAATQKRQELEAELAKVRAE 1763
Query: 194 PEQHCSSK-RSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
E +SK R+ S S + + E + +E R L + E D
Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 253 DWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPP 312
+ + EK + + K+ + L KE + E +R
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA-------ENERLRRLAEDEAFQ 1876
Query: 313 FSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRA 372
EEQ H A ++ R+ + ++ S + + D R+ EEE+LA +
Sbjct: 1877 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1936
Query: 373 AQVAQDE---EIARL-------LMAEEKKAYKKAKERE-KSSLDKRKQDPEWKPKTAKAA 421
A + E E+ R+ L ++E+ + A++R+ + ++R+++ E + + + AA
Sbjct: 1937 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAA 1996
Query: 422 NSKS 425
++
Sbjct: 1997 EEEA 2000
Score = 41.6 bits (96), Expect = 0.002
Identities = 81/430 (18%), Positives = 180/430 (41%), Gaps = 45/430 (10%)
Query: 29 LAHSLQEQEIEHHLASNV---QRNRL--VQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQ 83
++ +L+ E E LA +R RL V+ L+ +QL E +A+AQ ++ K+L+Q+
Sbjct: 1337 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1396
Query: 84 DCE--------IAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFP 135
E Q+K +I+ E +++++ + +I ++ E E+ R + E
Sbjct: 1397 MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE-AAERSRLRIEEEIR 1455
Query: 136 ATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPE 195
R ++ + G G +A + + + Q + + +++ + +
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1515
Query: 196 QHCSSKRSLSSSSSGKGR-----DNPHINNEQHER--KRSTQERPRRPLLPTISGEVFLS 248
+ S ++ + ++ K R + + E+ ER +++ ER R+ +V L
Sbjct: 1516 ELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV-------QVALE 1568
Query: 249 TECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRP 308
T E ++ + ++ +++ +R S + A +E R Q E + R
Sbjct: 1569 TAQRSAEAELQSKRASFAEKTAQLER-SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Query: 309 RTPPFSESEE-QLHLHDAGMKPRVMKEAVSTPSRM----AHRDQEWYDAEIARKLQEEEL 363
E E QL ++A ++ R+ E V+ + A + +E + E R+ + EE
Sbjct: 1628 E----RELERWQLKANEA-LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQ 1682
Query: 364 LATQVDMRAAQVAQDEEI----ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWK--PKT 417
Q ++ ++ + ++ A+ +A E++ + E E+ ++ + E +
Sbjct: 1683 AVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQRE 1742
Query: 418 AKAANSKSKE 427
A AA K +E
Sbjct: 1743 AAAATQKRQE 1752
Score = 38.5 bits (88), Expect = 0.014
Identities = 73/376 (19%), Positives = 142/376 (37%), Gaps = 20/376 (5%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQD 84
+D+T +E E +A R + + +QL EEDL Q L E+
Sbjct: 2259 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL------AEKML 2312
Query: 85 CEIAQEIQEKLAIEAERRRIQEKKD--EDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
E Q +QE ++AE +Q++K+ ++ AR LQE + Q ++ + F T A+
Sbjct: 2313 KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAE 2371
Query: 143 SYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLE-EPEQHCSSK 201
+ R + R + D + + + E+ L E ++ +
Sbjct: 2372 RQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV 2431
Query: 202 RSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDD--WETKIN 259
++L D + E +R ++ + L + E + + + ET+
Sbjct: 2432 QTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2491
Query: 260 HQTRNWEKQS--RHQDRLSPKSSQKAGLHCKEVVYG---RDHGQGEHRKRRHRPRTPPFS 314
Q+ EK S + + + + ++ L EV R+ Q + ++ + S
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS 2551
Query: 315 ESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQ 374
E + H+A R +E + + + +E E R ++ +LL Q A
Sbjct: 2552 MEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQ---HRAA 2608
Query: 375 VAQDEEIARLLMAEEK 390
+A EE+ +A K
Sbjct: 2609 LAHSEEVTASQVAATK 2624
Score = 37.7 bits (86), Expect = 0.023
Identities = 66/330 (20%), Positives = 126/330 (38%), Gaps = 58/330 (17%)
Query: 8 QSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEED- 66
Q + +K+V + A L + Q E LA Q+ L + L+ Q +E
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA---QQRALAEKMLKEKMQAVQEAT 2323
Query: 67 -LKAQAQLQKRYKDLEQQDCEIAQEIQEKLA-------------IEAERR---------- 102
LKA+A+L ++ K+L Q+ QE +E++A +EAER+
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2383
Query: 103 ----------RIQEKKDEDIARL-LQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQ 151
R Q + +ED R Q +E+ E+ R + + T + D
Sbjct: 2384 RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH 2443
Query: 152 PGSRRARELGSGFSRPCRLQRDGKTVKHKKE-----KPEHPLENLEEPEQ-HCSSKRSLS 205
R + +LQ++ K ++ K E + E L+ + +Q S K SL
Sbjct: 2444 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2503
Query: 206 SSSSGKGRDNPHIN-------------NEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
++ + E+ +R++ E+ R+ L+ ++ E +
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 253 DWETKINHQTRNWEKQSRHQDRLSPKSSQK 282
+ + + + E+Q R Q+ L + +Q+
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Score = 36.2 bits (82), Expect = 0.068
Identities = 70/421 (16%), Positives = 148/421 (35%), Gaps = 60/421 (14%)
Query: 24 LEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDL----QVAKQLQEEDLKAQAQLQK---- 75
L+ AH+ Q+ E L +Q+ + V L + A++ EE +A+ Q ++
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 76 ---------RYKDLEQQDCEI---AQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQE 123
R K ++ + AQ EKL EAE+ + + E A L Q++
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ-AALRQKQAADA 2165
Query: 124 EKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEK 183
E ++ K F E + +++++ T++ + E+
Sbjct: 2166 EMEKHKKFAE----------------------------QTLRQKAQVEQELTTLRLQLEE 2197
Query: 184 PEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISG 243
+H L+E Q L + ++ R + E + +E +
Sbjct: 2198 TDHQKNLLDEELQR------LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2251
Query: 244 EVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRK 303
+ + D+ + + + ++ + RLS + + A L + + R
Sbjct: 2252 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR-----QLAEEDLAQQRA 2306
Query: 304 RRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEEL 363
+ +E L + KE +R D+E ++A + Q +
Sbjct: 2307 LAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQR 2366
Query: 364 LATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANS 423
R +++ + E +L +AE +A +A+E + + ++ E +T A
Sbjct: 2367 TLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2426
Query: 424 K 424
K
Sbjct: 2427 K 2427
Score = 35.8 bits (81), Expect = 0.089
Identities = 76/432 (17%), Positives = 159/432 (36%), Gaps = 54/432 (12%)
Query: 15 KEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQ 74
++ R A +E LQ +E +H Q+N L+ +LQ K E + ++Q++
Sbjct: 2175 EQTLRQKAQVEQELTTLRLQLEETDH------QKN-LLDEELQRLKAEATEAARQRSQVE 2227
Query: 75 KRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQE-----KELQEEKKRKK 129
+ + Q E+++ K IEAE R + + ++ R LQE K++ EE R
Sbjct: 2228 EELFSVRVQMEELSKL---KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2284
Query: 130 HFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLE 189
+ A + +E RL+ + + ++ +KE +
Sbjct: 2285 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2344
Query: 190 NLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLST 249
L+E ++ + + L+ + G R + ER+R + +S
Sbjct: 2345 RLQEDKEQMAQQ--LAEETQGFQR------TLEAERQRQLE----------------MSA 2380
Query: 250 ECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAG--LHCKEVVYGR----------DHG 297
E + + ++ +R + R K +++ G LH E+
Sbjct: 2381 EAERLKLRVAEMSRAQARAEEDAQRFR-KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 298 QGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK 357
Q +H R R +E+L ++ + + ++ Q + ++ K
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 358 --LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKP 415
L + E Q + Q+ QDE + EE++ ++ E+E+ L ++ +
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2559
Query: 416 KTAKAANSKSKE 427
A+ + +E
Sbjct: 2560 HEAEEGVRRKQE 2571
Score = 31.6 bits (70), Expect = 1.7
Identities = 74/434 (17%), Positives = 170/434 (39%), Gaps = 61/434 (14%)
Query: 60 KQLQEEDLKAQAQLQ----KRYKDLEQQDCEIAQ----EIQEKLAIEAERRRIQEKKDED 111
KQ EE +A+AQ Q K K+ EQ+ AQ +++K A +AE + ++ ++
Sbjct: 2118 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 112 IARLLQ-EKELQ------EEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSG- 163
+ + Q E+EL EE +K+ + R A++ + + S+ EL S
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA---TEAARQRSQVEEELFSVR 2234
Query: 164 ------FSRPCRLQRDGKT-VKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNP 216
R++ + + + K+ + L+ E + + + + S ++ +
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR 2294
Query: 217 HINNEQHERKRSTQERPRRPLLPTISGEVFLSTEC---------------------DDWE 255
+ E ++R+ E+ + + + L E +
Sbjct: 2295 QLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMA 2354
Query: 256 TKINHQTRNWEKQ-SRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFS 314
++ +T+ +++ + R S++ L + R + E +R R +
Sbjct: 2355 QQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA---E 2411
Query: 315 ESEEQLHLHDAGMKPRV-MKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAA 373
E E+LH + + +V + + + + + D E IA +E+E L + +
Sbjct: 2412 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQL 2471
Query: 374 QVAQDEEIARLLMAEEKKAYKKAKEREKSSL---------DKRKQDPEWKPKTAKAANSK 424
+ + + + + + +E +A +++ EK SL +K K + ++ + AKA +
Sbjct: 2472 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2531
Query: 425 SKESDEPHHSKNER 438
++ + + ER
Sbjct: 2532 EEQQRQQQQMEQER 2545
Score = 30.4 bits (67), Expect = 3.7
Identities = 22/97 (22%), Positives = 49/97 (50%), Gaps = 4/97 (4%)
Query: 16 EVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQK 75
EV + + E+ EQE + L ++++ R QH+ + + ++E+L+ QL++
Sbjct: 2523 EVAKAQQLREEQQRQQQQMEQERQ-RLVASMEEARRRQHEAEEGVRRKQEELQ---QLEQ 2578
Query: 76 RYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDI 112
+ + E+ E Q ++E+L + E+ R E++
Sbjct: 2579 QRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEV 2615
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 48.9 bits (115), Expect = 1e-05
Identities = 93/424 (21%), Positives = 170/424 (40%), Gaps = 44/424 (10%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLE-QQ 83
E+H L+E E E + R + + ++L+ LKA L+ R + E Q
Sbjct: 1602 EEHVAVAQLRE-EAERRAQQQAEAERARE---EAERELERWQLKANEALRLRLQAEEVAQ 1657
Query: 84 DCEIAQEIQEKLAIEAERRRIQEKKDEDIA---RLLQEKELQEEKK------RKKHFPEF 134
+AQ EK EAER + K E+ A R L E+EL+++++ +++ E
Sbjct: 1658 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1717
Query: 135 PATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLE-E 193
R A++ E G+Q EL RLQR+ K+++ E L + E
Sbjct: 1718 ELIRLRAET---EQGEQQRQLLEEELA-------RLQREAAAATQKRQELEAELAKVRAE 1767
Query: 194 PEQHCSSK-RSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
E +SK R+ S S + + E + +E R L + E D
Sbjct: 1768 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1827
Query: 253 DWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPP 312
+ + EK + + K+ + L KE + E +R
Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA-------ENERLRRLAEDEAFQ 1880
Query: 313 FSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRA 372
EEQ H A ++ R+ + ++ S + + D R+ EEE+LA +
Sbjct: 1881 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1940
Query: 373 AQVAQDE---EIARL-------LMAEEKKAYKKAKERE-KSSLDKRKQDPEWKPKTAKAA 421
A + E E+ R+ L ++E+ + A++R+ + ++R+++ E + + + AA
Sbjct: 1941 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAA 2000
Query: 422 NSKS 425
++
Sbjct: 2001 EEEA 2004
Score = 41.6 bits (96), Expect = 0.002
Identities = 81/430 (18%), Positives = 180/430 (41%), Gaps = 45/430 (10%)
Query: 29 LAHSLQEQEIEHHLASNV---QRNRL--VQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQ 83
++ +L+ E E LA +R RL V+ L+ +QL E +A+AQ ++ K+L+Q+
Sbjct: 1341 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1400
Query: 84 DCE--------IAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFP 135
E Q+K +I+ E +++++ + +I ++ E E+ R + E
Sbjct: 1401 MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE-AAERSRLRIEEEIR 1459
Query: 136 ATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPE 195
R ++ + G G +A + + + Q + + +++ + +
Sbjct: 1460 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1519
Query: 196 QHCSSKRSLSSSSSGKGR-----DNPHINNEQHER--KRSTQERPRRPLLPTISGEVFLS 248
+ S ++ + ++ K R + + E+ ER +++ ER R+ +V L
Sbjct: 1520 ELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV-------QVALE 1572
Query: 249 TECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRP 308
T E ++ + ++ +++ +R S + A +E R Q E + R
Sbjct: 1573 TAQRSAEAELQSKRASFAEKTAQLER-SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1631
Query: 309 RTPPFSESEE-QLHLHDAGMKPRVMKEAVSTPSRM----AHRDQEWYDAEIARKLQEEEL 363
E E QL ++A ++ R+ E V+ + A + +E + E R+ + EE
Sbjct: 1632 E----RELERWQLKANEA-LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQ 1686
Query: 364 LATQVDMRAAQVAQDEEI----ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWK--PKT 417
Q ++ ++ + ++ A+ +A E++ + E E+ ++ + E +
Sbjct: 1687 AVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQRE 1746
Query: 418 AKAANSKSKE 427
A AA K +E
Sbjct: 1747 AAAATQKRQE 1756
Score = 38.5 bits (88), Expect = 0.014
Identities = 73/376 (19%), Positives = 142/376 (37%), Gaps = 20/376 (5%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQD 84
+D+T +E E +A R + + +QL EEDL Q L E+
Sbjct: 2263 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL------AEKML 2316
Query: 85 CEIAQEIQEKLAIEAERRRIQEKKD--EDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
E Q +QE ++AE +Q++K+ ++ AR LQE + Q ++ + F T A+
Sbjct: 2317 KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAE 2375
Query: 143 SYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLE-EPEQHCSSK 201
+ R + R + D + + + E+ L E ++ +
Sbjct: 2376 RQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV 2435
Query: 202 RSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDD--WETKIN 259
++L D + E +R ++ + L + E + + + ET+
Sbjct: 2436 QTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2495
Query: 260 HQTRNWEKQS--RHQDRLSPKSSQKAGLHCKEVVYG---RDHGQGEHRKRRHRPRTPPFS 314
Q+ EK S + + + + ++ L EV R+ Q + ++ + S
Sbjct: 2496 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS 2555
Query: 315 ESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQ 374
E + H+A R +E + + + +E E R ++ +LL Q A
Sbjct: 2556 MEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQ---HRAA 2612
Query: 375 VAQDEEIARLLMAEEK 390
+A EE+ +A K
Sbjct: 2613 LAHSEEVTASQVAATK 2628
Score = 37.7 bits (86), Expect = 0.023
Identities = 66/330 (20%), Positives = 126/330 (38%), Gaps = 58/330 (17%)
Query: 8 QSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEED- 66
Q + +K+V + A L + Q E LA Q+ L + L+ Q +E
Sbjct: 2271 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA---QQRALAEKMLKEKMQAVQEAT 2327
Query: 67 -LKAQAQLQKRYKDLEQQDCEIAQEIQEKLA-------------IEAERR---------- 102
LKA+A+L ++ K+L Q+ QE +E++A +EAER+
Sbjct: 2328 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2387
Query: 103 ----------RIQEKKDEDIARL-LQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQ 151
R Q + +ED R Q +E+ E+ R + + T + D
Sbjct: 2388 RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH 2447
Query: 152 PGSRRARELGSGFSRPCRLQRDGKTVKHKKE-----KPEHPLENLEEPEQ-HCSSKRSLS 205
R + +LQ++ K ++ K E + E L+ + +Q S K SL
Sbjct: 2448 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2507
Query: 206 SSSSGKGRDNPHIN-------------NEQHERKRSTQERPRRPLLPTISGEVFLSTECD 252
++ + E+ +R++ E+ R+ L+ ++ E +
Sbjct: 2508 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2567
Query: 253 DWETKINHQTRNWEKQSRHQDRLSPKSSQK 282
+ + + + E+Q R Q+ L + +Q+
Sbjct: 2568 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2597
Score = 36.2 bits (82), Expect = 0.068
Identities = 70/421 (16%), Positives = 148/421 (35%), Gaps = 60/421 (14%)
Query: 24 LEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDL----QVAKQLQEEDLKAQAQLQK---- 75
L+ AH+ Q+ E L +Q+ + V L + A++ EE +A+ Q ++
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 76 ---------RYKDLEQQDCEI---AQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQE 123
R K ++ + AQ EKL EAE+ + + E A L Q++
Sbjct: 2111 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ-AALRQKQAADA 2169
Query: 124 EKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEK 183
E ++ K F E + +++++ T++ + E+
Sbjct: 2170 EMEKHKKFAE----------------------------QTLRQKAQVEQELTTLRLQLEE 2201
Query: 184 PEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISG 243
+H L+E Q L + ++ R + E + +E +
Sbjct: 2202 TDHQKNLLDEELQR------LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2255
Query: 244 EVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRK 303
+ + D+ + + + ++ + RLS + + A L + + R
Sbjct: 2256 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR-----QLAEEDLAQQRA 2310
Query: 304 RRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEEL 363
+ +E L + KE +R D+E ++A + Q +
Sbjct: 2311 LAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQR 2370
Query: 364 LATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANS 423
R +++ + E +L +AE +A +A+E + + ++ E +T A
Sbjct: 2371 TLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2430
Query: 424 K 424
K
Sbjct: 2431 K 2431
Score = 35.8 bits (81), Expect = 0.089
Identities = 76/432 (17%), Positives = 159/432 (36%), Gaps = 54/432 (12%)
Query: 15 KEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQ 74
++ R A +E LQ +E +H Q+N L+ +LQ K E + ++Q++
Sbjct: 2179 EQTLRQKAQVEQELTTLRLQLEETDH------QKN-LLDEELQRLKAEATEAARQRSQVE 2231
Query: 75 KRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQE-----KELQEEKKRKK 129
+ + Q E+++ K IEAE R + + ++ R LQE K++ EE R
Sbjct: 2232 EELFSVRVQMEELSKL---KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2288
Query: 130 HFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLE 189
+ A + +E RL+ + + ++ +KE +
Sbjct: 2289 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2348
Query: 190 NLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLST 249
L+E ++ + + L+ + G R + ER+R + +S
Sbjct: 2349 RLQEDKEQMAQQ--LAEETQGFQR------TLEAERQRQLE----------------MSA 2384
Query: 250 ECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAG--LHCKEVVYGR----------DHG 297
E + + ++ +R + R K +++ G LH E+
Sbjct: 2385 EAERLKLRVAEMSRAQARAEEDAQRFR-KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 298 QGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK 357
Q +H R R +E+L ++ + + ++ Q + ++ K
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2503
Query: 358 --LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKP 415
L + E Q + Q+ QDE + EE++ ++ E+E+ L ++ +
Sbjct: 2504 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2563
Query: 416 KTAKAANSKSKE 427
A+ + +E
Sbjct: 2564 HEAEEGVRRKQE 2575
Score = 31.6 bits (70), Expect = 1.7
Identities = 74/434 (17%), Positives = 170/434 (39%), Gaps = 61/434 (14%)
Query: 60 KQLQEEDLKAQAQLQ----KRYKDLEQQDCEIAQ----EIQEKLAIEAERRRIQEKKDED 111
KQ EE +A+AQ Q K K+ EQ+ AQ +++K A +AE + ++ ++
Sbjct: 2122 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2181
Query: 112 IARLLQ-EKELQ------EEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSG- 163
+ + Q E+EL EE +K+ + R A++ + + S+ EL S
Sbjct: 2182 LRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA---TEAARQRSQVEEELFSVR 2238
Query: 164 ------FSRPCRLQRDGKT-VKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNP 216
R++ + + + K+ + L+ E + + + + S ++ +
Sbjct: 2239 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR 2298
Query: 217 HINNEQHERKRSTQERPRRPLLPTISGEVFLSTEC---------------------DDWE 255
+ E ++R+ E+ + + + L E +
Sbjct: 2299 QLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMA 2358
Query: 256 TKINHQTRNWEKQ-SRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFS 314
++ +T+ +++ + R S++ L + R + E +R R +
Sbjct: 2359 QQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA---E 2415
Query: 315 ESEEQLHLHDAGMKPRV-MKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAA 373
E E+LH + + +V + + + + + D E IA +E+E L + +
Sbjct: 2416 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQL 2475
Query: 374 QVAQDEEIARLLMAEEKKAYKKAKEREKSSL---------DKRKQDPEWKPKTAKAANSK 424
+ + + + + + +E +A +++ EK SL +K K + ++ + AKA +
Sbjct: 2476 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2535
Query: 425 SKESDEPHHSKNER 438
++ + + ER
Sbjct: 2536 EEQQRQQQQMEQER 2549
Score = 30.4 bits (67), Expect = 3.7
Identities = 22/97 (22%), Positives = 49/97 (50%), Gaps = 4/97 (4%)
Query: 16 EVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQK 75
EV + + E+ EQE + L ++++ R QH+ + + ++E+L+ QL++
Sbjct: 2527 EVAKAQQLREEQQRQQQQMEQERQ-RLVASMEEARRRQHEAEEGVRRKQEELQ---QLEQ 2582
Query: 76 RYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDI 112
+ + E+ E Q ++E+L + E+ R E++
Sbjct: 2583 QRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEV 2619
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,904,051
Number of Sequences: 37866
Number of extensions: 1077669
Number of successful extensions: 11742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 223
Number of HSP's successfully gapped in prelim test: 763
Number of HSP's that attempted gapping in prelim test: 6893
Number of HSP's gapped (non-prelim): 3753
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.