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Search of human proteins with 41152097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
(695 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 1383 0.0
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 96 9e-20
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 96 9e-20
gi|148746195 trichohyalin [Homo sapiens] 94 4e-19
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 88 2e-17
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 88 2e-17
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 88 2e-17
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 88 2e-17
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 88 3e-17
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 84 6e-16
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 83 8e-16
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 83 1e-15
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 82 1e-15
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 81 3e-15
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 81 3e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 80 6e-15
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 79 1e-14
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 79 1e-14
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 79 1e-14
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 78 2e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 78 3e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 77 5e-14
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 77 5e-14
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 76 9e-14
gi|56549694 enabled homolog isoform a [Homo sapiens] 76 1e-13
gi|39930375 enabled homolog isoform b [Homo sapiens] 76 1e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 76 1e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 76 1e-13
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 74 3e-13
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 74 3e-13
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 1383 bits (3579), Expect = 0.0
Identities = 695/695 (100%), Positives = 695/695 (100%)
Query: 1 MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALPQLKQPGKSISNWEVMERLKGMVQ 60
MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALPQLKQPGKSISNWEVMERLKGMVQ
Sbjct: 1 MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALPQLKQPGKSISNWEVMERLKGMVQ 60
Query: 61 NHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKID 120
NHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKID
Sbjct: 61 NHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKID 120
Query: 121 FPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALKESGSEKPSEDVLVKVFEK 180
FPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALKESGSEKPSEDVLVKVFEK
Sbjct: 121 FPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALKESGSEKPSEDVLVKVFEK 180
Query: 181 FGEIRNVDIPMLDPYREEMTGRNFHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLM 240
FGEIRNVDIPMLDPYREEMTGRNFHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLM
Sbjct: 181 FGEIRNVDIPMLDPYREEMTGRNFHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLM 240
Query: 241 YKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQR 300
YKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQR
Sbjct: 241 YKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQR 300
Query: 301 AEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEE 360
AEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEE
Sbjct: 301 AEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEE 360
Query: 361 RKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEE 420
RKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEE
Sbjct: 361 RKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEE 420
Query: 421 KERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVS 480
KERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVS
Sbjct: 421 KERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVS 480
Query: 481 ATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEK 540
ATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEK
Sbjct: 481 ATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEK 540
Query: 541 RCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK 600
RCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK
Sbjct: 541 RCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK 600
Query: 601 RERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERS 660
RERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERS
Sbjct: 601 RERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERS 660
Query: 661 RERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
RERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR
Sbjct: 661 RERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 96.3 bits (238), Expect = 9e-20
Identities = 90/310 (29%), Positives = 150/310 (48%), Gaps = 47/310 (15%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQ---ELEQQREEQKRR------------EKEAEER 298
KV D + L + +K+ + R+ LQ +EQ +EE+K++ EK EER
Sbjct: 558 KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 617
Query: 299 QRAEERKQK----ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE 354
E+ K+K ++EE+E RK+EE+ R+ Q++ E RR+Q+ L+K + EEQ++L+
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLR- 676
Query: 355 KIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAEL 414
K E K L QR Q R + + REQE++E++ +L +QE RR + +
Sbjct: 677 --KAAEAKRLAEQRE-QERREQERREQERREQERREQERREQERQLAEQERRREQERLQA 733
Query: 415 RRVEEEKERALGLQRK--ERELRERLLSILLSKKPDDS--------HTHDELGVAHADLL 464
R +E+E+AL LQ++ +REL E+ KK ++ E A
Sbjct: 734 ERELQEREKALRLQKEQLQRELEEK-------KKKEEQQRLAERQLQEEQEKKAKEAAGA 786
Query: 465 QPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEA-PCK 523
L++ V S ++ + P G + P PK +P+ G + + S +EA P K
Sbjct: 787 SKALNVTVDVQSPACTSYQMTPQGHRAP---PK---INPDNYGMDLNSDDSTDDEAHPRK 840
Query: 524 EVQSSCRVVP 533
+ + R P
Sbjct: 841 PIPTWARGTP 850
Score = 81.6 bits (200), Expect = 2e-15
Identities = 64/211 (30%), Positives = 119/211 (56%), Gaps = 26/211 (12%)
Query: 228 IQAMSALRGMKLMYKGE-DGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQR- 285
+QA + MK K + + K + K + L++ KK+ + K++E+E +R
Sbjct: 582 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK-KMEEVEARRK 640
Query: 286 -EEQKRR----EKEAEERQRAEERKQKELEELERERKREEKLR--------KREQKQRDR 332
EE+ RR ++E EER+ E ++K+ EE ER RK E R +REQ++R++
Sbjct: 641 QEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 700
Query: 333 ELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
E RR Q++ E+ + E+++QL E+ + E++ L A+R LQ R KA++L++++
Sbjct: 701 E-RREQERREQERREQERQLAEQERRREQERLQAERELQE---------REKALRLQKEQ 750
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEKER 423
+ E +++EE++RL E +L+ +E+K +
Sbjct: 751 LQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/171 (30%), Positives = 106/171 (61%), Gaps = 19/171 (11%)
Query: 280 ELEQQREEQKRREKEAEE--RQRAEERKQKELEELERERKREEKLRK------REQKQRD 331
E E+QR E RR++EAE+ RQ+ EE K++ LEE++ KREE+LRK R ++ ++
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 593
Query: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
+ ++ ++K ++ + +K +E++ E+ K A + ++ + + A+ ++ +Q
Sbjct: 594 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 392 EQKE----EKLRLQQQEERRRLQE-AELRRVEEEKERALGLQRKERELRER 437
E++E E L+ +++EE+ RL++ AE +R+ E++E+ +R+E+E RE+
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ----ERREQERREQ 700
Score = 60.1 bits (144), Expect = 7e-09
Identities = 48/149 (32%), Positives = 82/149 (55%), Gaps = 14/149 (9%)
Query: 312 LERERKREEKLRKREQ-----KQRDRELRRNQKKLEKLQAEE--QKQLQEKIKLEERKLL 364
+E+ER+R E LR++E+ +Q+ E +R + + KL+ EE +K LQ + ++E+ K
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594
Query: 365 LAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQE-ERRRLQEAELRRV------ 417
++ Q I E +AK +L E++ K++ + +E E RR QE E RR+
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 418 EEEKERALGLQRKERELRERLLSILLSKK 446
EEE+ LQ+K+ E +ERL +K+
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKR 683
Score = 32.7 bits (73), Expect = 1.2
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 19/133 (14%)
Query: 567 VSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPR-----KER 621
+ K ++++++ E +K + A K E ARR E R R +E
Sbjct: 606 IDEKTEKAKEERLAEEKAKKKAAAK--------KMEEVEARRKQEEEARRLRWLQQEEEE 657
Query: 622 RPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRE---RSRERRGSASRKHSR---HR 675
R H++ K + R + +++ RRE R +ERR R+ R R
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717
Query: 676 RRSERSRSRSPSR 688
+ +E+ R R R
Sbjct: 718 QLAEQERRREQER 730
Score = 32.7 bits (73), Expect = 1.2
Identities = 24/118 (20%), Positives = 46/118 (38%), Gaps = 1/118 (0%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRE-RSRARRASSREDGRPRKERR 622
++ R+ Q K E + R A LA++ ++E R + RR R + R++ R
Sbjct: 653 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 712
Query: 623 PHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSER 680
++ + RR R + K ++ +R +K +R +ER
Sbjct: 713 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 770
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 96.3 bits (238), Expect = 9e-20
Identities = 90/310 (29%), Positives = 150/310 (48%), Gaps = 47/310 (15%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQ---ELEQQREEQKRR------------EKEAEER 298
KV D + L + +K+ + R+ LQ +EQ +EE+K++ EK EER
Sbjct: 554 KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 613
Query: 299 QRAEERKQK----ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE 354
E+ K+K ++EE+E RK+EE+ R+ Q++ E RR+Q+ L+K + EEQ++L+
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLR- 672
Query: 355 KIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAEL 414
K E K L QR Q R + + REQE++E++ +L +QE RR + +
Sbjct: 673 --KAAEAKRLAEQRE-QERREQERREQERREQERREQERREQERQLAEQERRREQERLQA 729
Query: 415 RRVEEEKERALGLQRK--ERELRERLLSILLSKKPDDS--------HTHDELGVAHADLL 464
R +E+E+AL LQ++ +REL E+ KK ++ E A
Sbjct: 730 ERELQEREKALRLQKEQLQRELEEK-------KKKEEQQRLAERQLQEEQEKKAKEAAGA 782
Query: 465 QPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEA-PCK 523
L++ V S ++ + P G + P PK +P+ G + + S +EA P K
Sbjct: 783 SKALNVTVDVQSPACTSYQMTPQGHRAP---PK---INPDNYGMDLNSDDSTDDEAHPRK 836
Query: 524 EVQSSCRVVP 533
+ + R P
Sbjct: 837 PIPTWARGTP 846
Score = 81.6 bits (200), Expect = 2e-15
Identities = 64/211 (30%), Positives = 119/211 (56%), Gaps = 26/211 (12%)
Query: 228 IQAMSALRGMKLMYKGE-DGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQR- 285
+QA + MK K + + K + K + L++ KK+ + K++E+E +R
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK-KMEEVEARRK 636
Query: 286 -EEQKRR----EKEAEERQRAEERKQKELEELERERKREEKLR--------KREQKQRDR 332
EE+ RR ++E EER+ E ++K+ EE ER RK E R +REQ++R++
Sbjct: 637 QEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
Query: 333 ELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
E RR Q++ E+ + E+++QL E+ + E++ L A+R LQ R KA++L++++
Sbjct: 697 E-RREQERREQERREQERQLAEQERRREQERLQAERELQE---------REKALRLQKEQ 746
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEKER 423
+ E +++EE++RL E +L+ +E+K +
Sbjct: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Score = 77.8 bits (190), Expect = 3e-14
Identities = 62/180 (34%), Positives = 99/180 (55%), Gaps = 25/180 (13%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEE--RQRAEERKQKELEELERERKREEKLRKR 325
IK+ R +E E+QR E RR++EAE+ RQ+ EE K++ LEE++ KREE+LRK
Sbjct: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKV 577
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
Q + +++E+++ E++KQ+++K + K A+ RL E + A
Sbjct: 578 LQAR---------ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEE----RLAEEKAKKKAA 624
Query: 386 VK-------LREQEQKEEKLR-LQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K R+QE++ +LR LQQ+EE RR QE ++ EEE+ER +R +R
Sbjct: 625 AKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR 684
Score = 73.6 bits (179), Expect = 6e-13
Identities = 54/177 (30%), Positives = 109/177 (61%), Gaps = 21/177 (11%)
Query: 271 RQLERQKLQELEQQRE-EQKRREK-EAEERQRAEERKQKELEELER---ERKREEKLRKR 325
++ ERQ+L+ L ++ E EQ RR+K E ++R+R EE K K E L + R+R E++++
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
++KQ +++ + +K EK A+E++ +EK K + A + ++ + + A+
Sbjct: 591 KKKQIEQKFAQIDEKTEK--AKEERLAEEKAKKK-----AAAKKMEEVEARRKQEEEARR 643
Query: 386 VKLREQEQKE----EKLRLQQQEERRRLQE-AELRRVEEEKERALGLQRKERELRER 437
++ +QE++E E L+ +++EE+ RL++ AE +R+ E++E+ +R+E+E RE+
Sbjct: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ----ERREQERREQ 696
Score = 63.2 bits (152), Expect = 8e-10
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 305 KQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLL 364
K+KE + LE R++EE + R QK + + RR ++ K + +K LQ + ++E+ K
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 365 LAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQE-ERRRLQEAELRRV------ 417
++ Q I E +AK +L E++ K++ + +E E RR QE E RR+
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
Query: 418 EEEKERALGLQRKERELRERLLSILLSKK 446
EEE+ LQ+K+ E +ERL +K+
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKR 679
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/173 (23%), Positives = 80/173 (46%), Gaps = 32/173 (18%)
Query: 303 ERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
+R Q + R + KR R + +++LE L+ +E+ + + K+EE K
Sbjct: 500 QRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDK 559
Query: 363 LLLAQRNLQSIRLIAE------LLSRAKAVKLREQEQKEEKLRLQQQEER---------- 406
+R L+ ++L E L +R + +++E+++K+ + + Q +E+
Sbjct: 560 ----RRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 615
Query: 407 ----------RRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDD 449
++++E E RR +EE+ R L ++E E ER LL KK ++
Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE--ERRHQELLQKKKEE 666
Score = 32.7 bits (73), Expect = 1.2
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 19/133 (14%)
Query: 567 VSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPR-----KER 621
+ K ++++++ E +K + A K E ARR E R R +E
Sbjct: 602 IDEKTEKAKEERLAEEKAKKKAAAK--------KMEEVEARRKQEEEARRLRWLQQEEEE 653
Query: 622 RPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRE---RSRERRGSASRKHSR---HR 675
R H++ K + R + +++ RRE R +ERR R+ R R
Sbjct: 654 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713
Query: 676 RRSERSRSRSPSR 688
+ +E+ R R R
Sbjct: 714 QLAEQERRREQER 726
Score = 32.7 bits (73), Expect = 1.2
Identities = 24/118 (20%), Positives = 46/118 (38%), Gaps = 1/118 (0%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRE-RSRARRASSREDGRPRKERR 622
++ R+ Q K E + R A LA++ ++E R + RR R + R++ R
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 708
Query: 623 PHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSER 680
++ + RR R + K ++ +R +K +R +ER
Sbjct: 709 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/184 (32%), Positives = 117/184 (63%), Gaps = 10/184 (5%)
Query: 269 KKRQLERQKLQELEQQREEQKRR--EKEAEERQRAEERKQKELEELERERKREEKLRKRE 326
++ + ER+K Q Q EE++ R + E EER+ +ER++++L E+E +RE++L+++E
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR-EQEERREQRLKRQE 523
Query: 327 QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAV 386
+++R ++ R++++L + Q E ++QL +K EE K L +R Q RL E R +
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQL---LKREEEKRLEQERREQ--RLKREQEERRDQL 578
Query: 387 KLREQEQKEEKLRLQQQEE-RRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSK 445
RE+E+++++L+ +Q+E +RL+ E+ R+E+E+ R L+R+E E ER +L S+
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE-EERRQQLLKSE 637
Query: 446 KPDD 449
+ ++
Sbjct: 638 EQEE 641
Score = 90.1 bits (222), Expect = 6e-18
Identities = 58/192 (30%), Positives = 118/192 (61%), Gaps = 24/192 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
++ + E+Q +E E++RE+Q RRE+E EER+ + R+++E E E++ +RE++LR+ +Q
Sbjct: 331 QEERREQQLRREQEERREQQLRREQE-EERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 329 QRDRELRRNQ--------KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIR------ 374
+R+++LRR Q ++ ++L+ E+Q + +++++ E+ + Q++ Q R
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 375 ---LIAELLSRAKAVKLREQEQKEEKLRLQQQEERR----RLQEAELRRVEEEKERALGL 427
+ L R + + EQE+++++L+ Q+EERR +L+E E R +E +E+ L
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ--L 507
Query: 428 QRKERELRERLL 439
+R++ E RE+ L
Sbjct: 508 RREQEERREQRL 519
Score = 89.7 bits (221), Expect = 8e-18
Identities = 51/185 (27%), Positives = 110/185 (59%), Gaps = 13/185 (7%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRA-----EERKQKELEELERERKREEKLRK 324
+R+ E ++ ++ E++RE+Q+RRE++ E R++ EER++++L + E +RE++LR+
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 325 REQKQR-------DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIA 377
++++R +++LRR Q+ + Q ++QL+ + +L + L ++ L+ + +
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRRL-QEAELRRVEEEKERALGLQRKERELRE 436
+ + EQE++E++L+ +Q+E R L +E E R E+E+ + + +E E RE
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 437 RLLSI 441
R L +
Sbjct: 487 RWLKL 491
Score = 89.4 bits (220), Expect = 1e-17
Identities = 62/208 (29%), Positives = 124/208 (59%), Gaps = 20/208 (9%)
Query: 261 KHLSDASIKKRQLERQKL----QELEQQ-----REEQKRREKEAEERQRAEE-RKQKELE 310
+ L + + R+LERQ+L QE EQQ RE+Q RR++E E R++ EE R+Q+E
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 311 ELERERKREEKLRKREQKQRDRELRRNQ---KKLEKLQAEEQKQLQEKIKLEERKLLLAQ 367
E ++E +RE++LR+ ++++R+++LRR Q ++ ++L+ E++++ +E+ E++L Q
Sbjct: 329 E-QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 368 RNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGL 427
+ + +L E R + REQ+ + E+ ++Q+ RR +E + E++ R L
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 428 QRKERELRERLLSILLSKKPDDSHTHDE 455
+R++ E R+ L K+ +++ H++
Sbjct: 448 KREQEERRDWL------KREEETERHEQ 469
Score = 87.4 bits (215), Expect = 4e-17
Identities = 55/194 (28%), Positives = 112/194 (57%), Gaps = 19/194 (9%)
Query: 262 HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEK 321
H ++ + QL R++L EL ++ E+K++++ + + +E ++KE + E ++EE+
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 322 LRKREQKQRDRELRRNQKKLEKLQAEE-------QKQLQEKIKLE---------ERKLLL 365
+ E+ QR REL+ +++L KL+ +E ++Q Q++++ E ER+
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 366 AQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERAL 425
+R Q R + R + ++ ++E++E++LR +Q+EERR E +LRR +EE+ R
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR---EQQLRREQEEERREQ 375
Query: 426 GLQRKERELRERLL 439
L+R+++ RE+ L
Sbjct: 376 QLRREQQLRREQQL 389
Score = 86.7 bits (213), Expect = 7e-17
Identities = 60/184 (32%), Positives = 111/184 (60%), Gaps = 14/184 (7%)
Query: 269 KKRQLERQKLQELEQQREEQKRRE------KEAEERQRAEERKQKELEELE---RERKRE 319
+K+Q R++ + Q+ EE++ R+ KE E+ Q E ++Q+EL+E E R+ +R+
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 320 EKLRKR-EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAE 378
E R+R E++Q+ + LRR Q+ K + E ++Q +E+ + +ER+ +R Q +R E
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 379 LLSRAKAVKLREQEQKEEKLRLQQQEERRRLQ---EAELRRVEEEKERALGLQRKERELR 435
+ + +E+E++E++LR +Q+EERR Q E +LRR E++ R L+R+++ R
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR-EQQLRREQQLRREQQLRR 403
Query: 436 ERLL 439
E+ L
Sbjct: 404 EQQL 407
Score = 86.7 bits (213), Expect = 7e-17
Identities = 63/190 (33%), Positives = 110/190 (57%), Gaps = 21/190 (11%)
Query: 269 KKRQLERQKLQELEQQ--REEQKRREKEAE------ERQRAEERKQKELEELERERKREE 320
+++QL R++ EQQ RE+Q RRE+E E E++R E+R ++E EE KREE
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 321 KLRKREQKQRDRELRRNQKKLE-----KLQAEEQKQLQE------KIKLEERKLLLAQRN 369
+ + EQ++R ++L+R+Q++ KL+ EE+++ QE + + EER+ +R
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 370 LQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQR 429
+ RL L R++ REQE++ E+L +++E+R + E R E++ER L +
Sbjct: 523 EEEERLQQRL--RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 430 KERELRERLL 439
+E E R++ L
Sbjct: 581 REEERRQQRL 590
Score = 86.3 bits (212), Expect = 9e-17
Identities = 59/177 (33%), Positives = 109/177 (61%), Gaps = 16/177 (9%)
Query: 272 QLERQKLQELEQQREEQKRREKEAE-----ERQRAEERKQKEL---EELERER-KREEKL 322
+LE ++ +E +++RE+Q RRE+E +RQ EER Q+ L ++L RE+ +R E+L
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 323 RKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSR 382
KRE+++R + RR Q +L+ E++++ + +K EE + + Q RL + L R
Sbjct: 550 LKREEEKRLEQERREQ----RLKREQEERRDQLLKREEERRQQRLKREQEERL-EQRLKR 604
Query: 383 AKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLL 439
+ +L ++E++E++L+ ++ EE RR Q L+ E+E+ R L+R+++E RE+ L
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQ--LLKSEEQEERRQQQLRREQQERREQRL 659
Score = 85.1 bits (209), Expect = 2e-16
Identities = 56/203 (27%), Positives = 114/203 (56%), Gaps = 28/203 (13%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER-------- 316
+ +++ Q E ++ Q+L +++EE++R ++ E+Q E++ + ++L RE+
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 317 KREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE--ERKLLLA-------- 366
+RE++LR+ +Q +R+++LRR Q++ Q EQ++ ++++K E ER+ L
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 367 --QRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERA 424
+R Q ++ E R + +KL E+E++E++ R +QQ R + + E R +E+E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 425 L--------GLQRKERELRERLL 439
L L+R++ E RE+LL
Sbjct: 528 LQQRLRSEQQLRREQEERREQLL 550
Score = 84.3 bits (207), Expect = 3e-16
Identities = 52/174 (29%), Positives = 113/174 (64%), Gaps = 4/174 (2%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
++++L+RQ+ +E QQR +++ + +E +R + K++E + LE+ER RE++L++ +++
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER-REQRLKREQEE 573
Query: 329 QRDRELRRNQ-KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVK 387
+RD+ L+R + ++ ++L+ E++++L++++K EE + L Q + RL E + +
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL-EQEERREQRLKREEPEEERRQQ 632
Query: 388 LREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRK-ERELRERLLS 440
L + E++EE+ + Q + E++ +E L+R EEE+ L+R+ E E RE+ L+
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Score = 83.6 bits (205), Expect = 6e-16
Identities = 57/180 (31%), Positives = 115/180 (63%), Gaps = 13/180 (7%)
Query: 270 KRQLERQKLQELEQQREE---QKRREKEAEERQRAEERKQKELEELERER----KREEKL 322
+R+ E ++ Q L++Q EE Q+R E + R+ EER+++ L+ E +R +RE++L
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Query: 323 RKREQKQRDRELRR-NQKKLEKLQAEEQKQLQEKIKLEE-RKLLLAQRNLQSI-RLIAEL 379
++ ++++RD+ L+R +++ ++L+ E++++L++++K EE +L +R Q + R E
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 380 LSRAKAVKLREQEQ-KEEKLRLQQQE--ERRRLQEAELRRVEEEKERALGLQRKERELRE 436
R + +K EQE+ ++++LR +QQE E+R +E E R+E+ +R +R+E+EL E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Score = 83.6 bits (205), Expect = 6e-16
Identities = 63/190 (33%), Positives = 116/190 (61%), Gaps = 15/190 (7%)
Query: 260 TKHLSDASIKKRQLERQKLQELEQ--QREEQKRREKEAEERQ-RAEERKQKELEELERER 316
T + A ++ + E+Q LQE E+ QREE+++R ++ +ERQ R EE+ Q+E E+L RE
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947
Query: 317 KREEKLRKREQKQRDRELRRNQKKLEKLQAE--EQKQLQEKIKLEERKLLLAQRNLQSIR 374
+ EK R++E++++ R+ ++ Q+K E+L E E+++ QE+ K + L Q Q +R
Sbjct: 948 R--EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Query: 375 LIAELLSR---AKAVKLREQEQKEEKLRLQQQEERRRLQEAELR-----RVEEEKERALG 426
E R + + +++ Q+EE+ L+++ E+RRLQE E + +++E+E+ LG
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 427 LQRKERELRE 436
+R+ R +E
Sbjct: 1066 EERETRRRQE 1075
Score = 83.2 bits (204), Expect = 8e-16
Identities = 54/189 (28%), Positives = 101/189 (53%), Gaps = 24/189 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
+ RQLE + Q Q+R+EQ+R E EE + KQ+ LE+ +R+R+ EE R+R++
Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEE----QSEKQERLEQRDRQRRDEELWRQRQEW 180
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLL----------LAQRNLQSIRLI-- 376
Q E R +++L+ + E ++ ++ +L R+LL QR + R+
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 377 --------AELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQ 428
E + R + KL+E+E + ++ +++E+ R+L+ ELRR +E+E+
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 429 RKERELRER 437
R+E++LR +
Sbjct: 301 RREQQLRRK 309
Score = 82.4 bits (202), Expect = 1e-15
Identities = 53/180 (29%), Positives = 110/180 (61%), Gaps = 9/180 (5%)
Query: 270 KRQLERQKLQEL---EQQ--REEQKRREK--EAEERQRAEERKQKELEELERERKREEKL 322
KRQ E ++LQ+ EQQ RE+++RRE+ + EE +R E+ ++++ + E+E +R++ L
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 323 RKREQKQRDRELRRNQKKLE-KLQAEEQKQLQEKIKLEER-KLLLAQRNLQSIRLIAELL 380
++ E++++ R R +++LE +L+ EE ++L+++ + E+R K + + L +E
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 381 SRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLS 440
+ +LR ++Q+ + RL+++EE RL++ R EEE+ + ++ + RER+ S
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Score = 81.3 bits (199), Expect = 3e-15
Identities = 58/203 (28%), Positives = 113/203 (55%), Gaps = 31/203 (15%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAE-------------------ERQRAEERKQKEL 309
++ QL++++ Q L ++RE+++R+E+E + E++R +ER++K
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 310 EELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE---KIKLEERKLLLA 366
EE E +++ E+ LR+ +K+R +E R +K ++LQ EE++ L+E K +L+ER+
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 367 QRN---LQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKER 423
+ + +L+ E + +L Q +KEE+L QQEE + L+E +R +E+ER
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEEL---QQEEEQLLREEPEKRRRQERER 1108
Query: 424 ALGLQRKERELRERLLSILLSKK 446
R+E EL++ +L ++
Sbjct: 1109 QC---REEEELQQEEEQLLREER 1128
Score = 81.3 bits (199), Expect = 3e-15
Identities = 65/194 (33%), Positives = 110/194 (56%), Gaps = 25/194 (12%)
Query: 269 KKRQLERQKLQELEQQRE-------EQKRREKE----AEERQRAEERKQKELEELERERK 317
KK +L++++ Q L ++RE E++ RE+E EE+ EER+ + +ELER+ +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 318 REEKLRKRE--------QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQ-R 368
+EE+L++ E +K+R +E R ++ E+LQ EE++ L+E+ + R+ L Q R
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 369 NLQSIRLIAELLSRAKAVKLREQE---QKEEKLRLQQQEERRRLQEAELRRVEEEKE--R 423
+ ++ E L R + K R QE Q E+ LQQ+EE+ +E E RR E E++
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 424 ALGLQRKERELRER 437
LQR++R+ R R
Sbjct: 1202 EEELQRQKRKQRYR 1215
Score = 80.9 bits (198), Expect = 4e-15
Identities = 61/178 (34%), Positives = 104/178 (58%), Gaps = 10/178 (5%)
Query: 263 LSDASIKKRQLERQKL--QELEQQREEQKRREKEAEERQRAE-ERKQKELEELERERKRE 319
L + K+R+ ER+K +E E Q+EE++ +E E+R+R E ER+ ++ +EL++E E
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE--EE 1031
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQ-RNLQSIRLIAE 378
+ LR+ +K+R +E R ++ E+LQ EE++ L E+ + R+ L Q R + ++ E
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 379 LLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
L R + K R QE++ R ++EE + +E +L R E EK R L+R+ RE E
Sbjct: 1092 QLLREEPEKRRRQERE----RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Score = 79.3 bits (194), Expect = 1e-14
Identities = 61/182 (33%), Positives = 108/182 (59%), Gaps = 22/182 (12%)
Query: 274 ERQKLQELEQQREEQKRREK----EAEERQRAEERKQKELEELERERKREEKLRKRE--- 326
+RQ+ QE E++R E+++ + E EE E+ +++EL EL R+ + E++ ++RE
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Query: 327 ---QKQRDRELRRNQ----KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAEL 379
Q++ ++E R+ + K+ EKLQ EE+ Q Q +++ EE +L +R Q +R +
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQ-EEEPQRQRELQEEEEQLRKLER--QELRRERQE 292
Query: 380 LSRAKAVKLREQE--QKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ + REQ+ +K+E+ R +QQEERR QE RR ++E+ R L+R++ E RE+
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQE---RREQQEERREQQLRREQEERREQ 349
Query: 438 LL 439
L
Sbjct: 350 QL 351
Score = 79.3 bits (194), Expect = 1e-14
Identities = 49/174 (28%), Positives = 107/174 (61%), Gaps = 4/174 (2%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
+KR+ +K +E Q+ E Q++RE + EE Q + +Q+ E + E +++++LR+ +Q
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
+R +E R +++ E+ + +E+++ QE+ + ++ + +R Q +R E R + ++
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 389 -REQEQKEEKLRLQQQ--EERRRLQEAELRRVEEEKERALGLQRKERELRERLL 439
+E+E++E++LR +QQ E++ +E +LRR E++ R L+R+++ RE+ L
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQQL 419
Score = 79.0 bits (193), Expect = 1e-14
Identities = 60/193 (31%), Positives = 107/193 (55%), Gaps = 29/193 (15%)
Query: 269 KKRQLERQKLQELEQQ--REEQKRREKEAEERQ--------------RAEERKQKELEEL 312
+K+ E ++LQ+ E+Q REE+++R ++ ERQ EER+++ L+E
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 313 ERERKREEKLRKREQK--------QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLL 364
ER+ + EE+L++ E++ +R +EL R +K E+LQ EE++ L+E+ + R+
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 365 LAQ-RNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKER 423
Q R + ++ E L R + RE+ +++E R ++EE + +E +L R E EK R
Sbjct: 1107 ERQCREEEELQQEEEQLLREE----REKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 424 ALGLQRKERELRE 436
L+R+ RE E
Sbjct: 1163 RQELERQYREEEE 1175
Score = 78.6 bits (192), Expect = 2e-14
Identities = 50/171 (29%), Positives = 102/171 (59%), Gaps = 6/171 (3%)
Query: 274 ERQKLQELEQQREEQKRREKEAE---ERQRAEERKQKELEELERERKREEKLRKREQKQR 330
E +KLQE E QR+ + + E+E ERQ +Q+E ++ +R R+ ++ RK+E+++R
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 331 DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLRE 390
+++ R +++ + Q EE+++ Q + + EER+ +R + R +L + + +
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 391 QEQKEEKLRLQQQ--EERRRLQEAELRRVEEEKERALGLQRKERELRERLL 439
Q ++E++LR +QQ E++ +E +LRR E++ R L+R+++ RE+ L
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQQL 425
Score = 77.8 bits (190), Expect = 3e-14
Identities = 72/255 (28%), Positives = 121/255 (47%), Gaps = 63/255 (24%)
Query: 269 KKRQLERQKLQELEQQ---REEQKRREKEAEERQRAEERKQKELEE--------LERERK 317
+K + E Q LQE E+Q R+E+ R+ +E E++ R +ER++K L+E LER+ +
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 318 REEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIA 377
EE+LR+ ++++ R R +K LE+ Q +++ Q+ + E + + L+ R
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 378 ELLSRAKAVKLREQEQ---------------------KEEKLRLQQQE------------ 404
+L S+ K RE+EQ +EE+L+L++QE
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR 1846
Query: 405 --------ERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTH--- 453
E+ R +E EL + EE+K R Q +ER+LRE I +K + H
Sbjct: 1847 AEEQFATQEKSRREEQELWQEEEQKRR----QERERKLREE--HIRRQQKEEQRHRQVGE 1900
Query: 454 --DELGVAHADLLQP 466
+ G H LL+P
Sbjct: 1901 IKSQEGKGHGRLLEP 1915
Score = 77.4 bits (189), Expect = 4e-14
Identities = 58/196 (29%), Positives = 110/196 (56%), Gaps = 16/196 (8%)
Query: 269 KKRQLERQKLQELEQQ--REEQKRREKEAE-ERQRAEERKQKELEELERERKREEKLRKR 325
+++QL R++ EQQ RE+Q RRE++ E+Q E++ + ++L RE++ E +K
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 326 EQKQRDRELRRNQKKLE---KLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRL----IAE 378
EQ++R++ L+R Q++ K + E ++ QE+ K + ++ +R + ++L E
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 379 LLSRAKAVKLREQEQKEEKLRLQQQEERRRLQ-----EAELRRVEEEKERALGLQRKERE 433
R + REQE++ E+ RL++QEE RLQ E +LRR +EE+ L + +E+
Sbjct: 499 QQERREQQLRREQEERREQ-RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 434 LRERLLSILLSKKPDD 449
L + L ++ ++
Sbjct: 558 LEQERREQRLKREQEE 573
Score = 76.6 bits (187), Expect = 7e-14
Identities = 88/438 (20%), Positives = 188/438 (42%), Gaps = 64/438 (14%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
KR+ E ++ Q L+++ E +++R K +E + + K++E+E LE+E +RE++L++ E ++
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 330 RDREL-----RRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
R+ + +++ ++L+ E+Q++ ++++K EE + L QR ++ E R +
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR----LKREHEEERREQ 683
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQ-EAELRRVE----EEKERALGLQRKERELRERLL 439
+ EQEQ E+++ + + + +L+ EA+ R+ + K+ ++++ E R R
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 440 SILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKES 499
S L ++ + +H + D + S L +PP +E
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQW-------QAEEKSERGRQRLSARPPLREQRER 796
Query: 500 PAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKG 559
E + Q R +PE+ E+R ++ K
Sbjct: 797 QLRAE------------------ERQQREQRFLPEEEEKEQRRR--------QRREREKE 830
Query: 560 IPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSR-----ED 614
+ E E+++ R + + DGL + +R RS+ +R + E+
Sbjct: 831 LQFLE----------EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE 880
Query: 615 GRPRKERRPHKKHAYKDDSPRRRS-TSPDHTRSRRSHSKDRHRRERSRE-RRGSASRKHS 672
R R+ + K A ++ + + + +R + R R+E+ R+ R ++
Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Query: 673 RHRRRSERSRSRSPSRHR 690
R ER + R R R
Sbjct: 941 EQLLREEREKRRRQERER 958
Score = 76.6 bits (187), Expect = 7e-14
Identities = 57/188 (30%), Positives = 103/188 (54%), Gaps = 25/188 (13%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE----RKQKELEELE----------- 313
++++ ERQ +E + Q+EE++ +E E+R+R E RK K+L++ E
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR 981
Query: 314 RERKREEKLRKREQKQRDRE--LRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQ 371
R ++RE+K R+ E+ Q++ E LR ++K + + E Q + +++++ EE +LL +R +
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 372 SIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAE--LRRVEEEKERALGLQR 429
L R + + E+ Q+EE+ L ++ E RR QE E R+ EE ++ L R
Sbjct: 1042 ------RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 430 KERELRER 437
+E E R R
Sbjct: 1096 EEPEKRRR 1103
Score = 76.3 bits (186), Expect = 9e-14
Identities = 57/194 (29%), Positives = 111/194 (57%), Gaps = 25/194 (12%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
D +K+ + RQ+ + EQ+ ++R ++E ER EER+++ L+ E E +R ++L K
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 325 REQKQ--RDRELRRNQKKLEK---LQAEEQKQLQEKIKL----EERKLLLAQRNLQSIR- 374
E+++ R ++LRR Q++ + + EE+++L++++K E R+ LA+ + R
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Query: 375 ------------LIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKE 422
L +E +R V R ++Q+ ++ R Q+QEE+RR +E+EL+ +E+E
Sbjct: 696 RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR-RRQEQEEKRRRRESELQ--WQEEE 752
Query: 423 RALGLQRKERELRE 436
RA Q++E + R+
Sbjct: 753 RAHRQQQEEEQRRD 766
Score = 76.3 bits (186), Expect = 9e-14
Identities = 59/200 (29%), Positives = 113/200 (56%), Gaps = 23/200 (11%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREE-------QKRREKEAEERQRAEERKQKELE 310
D L + +++++ ER+ +++ +Q R + Q+R K E+ Q +ER++++L
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Query: 311 ELERERK---REEKLRKREQKQ-----RDRELRRNQKKLEKLQAEEQKQLQE---KIKLE 359
ER+RK E +LR++E++Q RDR+ R ++ L++ + E+Q + QE K + E
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE-EQQLRRQERDRKFREE 1696
Query: 360 ERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE---QKEEKLRLQQQEERRRLQEAELRR 416
E++L +R + ++ +L + K RE+E Q+ E+ +L++QE R++ E E R
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 417 VEEEKERALGLQRKERELRE 436
E E E+ L Q ++R+ RE
Sbjct: 1757 PERE-EQQLRRQERDRKFRE 1775
Score = 75.5 bits (184), Expect = 2e-13
Identities = 56/184 (30%), Positives = 104/184 (56%), Gaps = 27/184 (14%)
Query: 265 DASIKKRQLERQKLQELEQQREE--------QKRREKEAEERQRAEERKQKELEELERER 316
+ +++++LER K +E EQ R+E Q+R K EE Q ER++++L ER+R
Sbjct: 1713 EQQLRRQELER-KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 317 K--REEKLR--KREQKQRDRELRRNQKKLEKLQAEEQKQL-------------QEKIKLE 359
K EE+LR + EQ+ R +E R ++ E+L+ E ++Q +E+++LE
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 360 ERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEE 419
E++ L Q + R + ++ K+ + EQE +E+ + ++QE R+L+E +RR ++
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKS-RREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 420 EKER 423
E++R
Sbjct: 1891 EEQR 1894
Score = 75.1 bits (183), Expect = 2e-13
Identities = 64/218 (29%), Positives = 120/218 (55%), Gaps = 39/218 (17%)
Query: 269 KKRQLERQKLQELEQQREEQKRRE----KEAEERQRAEERKQKELEELERERK-REEKLR 323
+K Q E+Q L+E +REE++RR+ K EE Q +ER+++ L ER+RK REE+LR
Sbjct: 1312 RKSQEEKQLLRE---EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR 1368
Query: 324 KREQKQR----DRELRRNQKKLEKLQAEEQKQLQE-----------KIKLEERKLLLAQR 368
+EQ ++ ++ LRR +++ + L+ E+Q + QE K + EE++L +R
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Query: 369 NLQSIRLIAELLSRAKAVKLREQEQK-----------EEKLRLQQQEERRRLQEAELRRV 417
+ + ++ + + K E+EQ+ EE+L +++E++ QE + + +
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 418 EEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
EEE++ L Q ++R+ RE+ L S++P+ +E
Sbjct: 1489 EEEQQ--LRRQERDRKFREQELR---SQEPERKFLEEE 1521
Score = 74.7 bits (182), Expect = 3e-13
Identities = 98/451 (21%), Positives = 193/451 (42%), Gaps = 56/451 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAE-ERKQKELEELERERKREEKLRKREQ 327
++++LERQ +E E Q+EE++ +E E+R+R E ER+ +E EEL++E EE+L + EQ
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE---EEQLLREEQ 1188
Query: 328 KQRDRELRRNQKKLEKLQAEEQKQL----------------QEKIKLEERKLLLAQRNLQ 371
++R +E R ++ E+LQ +++KQ +++ + + K+ R +
Sbjct: 1189 EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE 1248
Query: 372 SIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRK 430
R + + R + + Q E+ +++ERRR Q+ + EEE+ ER + K
Sbjct: 1249 QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308
Query: 431 ERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQ 490
R+ + + LL ++ ++ E + Q +LQ PL Q
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ----LLQEREE--------QPLRRQ 1356
Query: 491 PPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCI 550
+E + G + EE + + + + E+ + RC
Sbjct: 1357 ERDRKFREEELRHQEQG-----RKFLEEEQRLRRQERERKFLKEE--QQLRCQEREQQLR 1409
Query: 551 PDNNQQPKGIPACEQNVSRKDT----RSEQDKCNREPSKGRGRATGDGL-ADRHKRERSR 605
D +++ EQ +SR++ R E+ + R+ + + L +RH++ R
Sbjct: 1410 QDRDRK---FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 606 ARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRR------ER 659
+ RE+ + ++ R K +++ RR R + S++ R+ +
Sbjct: 1467 EQLLQEREEQQLHRQERDRK--FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 660 SRERRGSASRKHSRHRRRSERSRSRSPSRHR 690
R++R + + RR ER + R R R
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Score = 74.3 bits (181), Expect = 3e-13
Identities = 60/195 (30%), Positives = 104/195 (53%), Gaps = 36/195 (18%)
Query: 270 KRQLERQKLQELEQQREEQ-KRREKEAEERQRAEERKQKELEELERE------------R 316
+ Q ERQ E QQRE++ E+E E+R+R ++KEL+ LE E +
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 317 KREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQ---------LQEKIKLEERKLLLAQ 367
+ E+ L++ ++++R +E RR+QK +L+ E +++ LQE+++ E++ L +
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 368 RNLQSIRLIAELLSRAKAVKLREQEQK---EEKLRLQQQEERRRLQEAELRRVEEEKERA 424
LQ R + K R QEQ+ E+ +LQQ+EE+ +E E RR +E+ER
Sbjct: 911 EELQ----------REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR-RQERERQ 959
Query: 425 LGLQRKERELRERLL 439
+K ++ E+LL
Sbjct: 960 YRKDKKLQQKEEQLL 974
Score = 74.3 bits (181), Expect = 3e-13
Identities = 58/194 (29%), Positives = 109/194 (56%), Gaps = 34/194 (17%)
Query: 269 KKRQLERQKLQELEQQRE--------EQKRREKEAEERQRAEERKQKELEELERERK--- 317
+K + E Q+++ E++R+ Q+R K EE Q +ER++++L ER+RK
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 318 REEKLRK--REQKQRDRELRRNQKKLEKLQAEEQ---KQLQEKIKLEERKLLLAQRNLQS 372
E++LR+ R++K R++ELR + + + L+ E+Q +Q Q K EE++L +R Q
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 373 IRLIAELLSRAKAVKLREQEQ-----KEEKLRLQQQEERRRLQEAELRRVEEEK-----E 422
+ + K RE+EQ +E++L Q+++ + RL+E ++RR E+E+ E
Sbjct: 1550 --------RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 423 RALGLQRKERELRE 436
+ L Q +++LR+
Sbjct: 1602 QQLRRQEGQQQLRQ 1615
Score = 73.9 bits (180), Expect = 5e-13
Identities = 108/450 (24%), Positives = 189/450 (42%), Gaps = 88/450 (19%)
Query: 269 KKRQLERQKLQELEQ-QREEQKRREKEAE-------ERQRAEE--RKQKELEELERERKR 318
++R+ E Q L+E EQ QR E+ ++ +E E ER+R++E R QK +LE ERKR
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 319 -----------EEKLRKREQ---------KQRDRELRRNQKKLEKLQAEEQ-KQLQEKIK 357
+E+LRK +Q ++ +RE RR Q++ + + EEQ +Q +E++
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 358 LEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQ-EAELRR 416
EER+ Q + R K ++ +QKEE+L ++ E+RRR + E + R
Sbjct: 945 REEREKRRRQERERQYR------------KDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 417 VEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSS 476
EE ++ L R+ERE R R +K D+ +E LL+ + +
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE------QLLREEREKRRLQE- 1045
Query: 477 GCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDG 536
++ E + + G E +E++ R E
Sbjct: 1046 ------------------RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 537 SPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLA 596
E++ +L P+ ++ + C + ++ + E+++ RE + R R
Sbjct: 1088 QEEEQ----LLREEPEKRRRQERERQCRE---EEELQQEEEQLLREEREKRRRQE----L 1136
Query: 597 DRHKRERSRARRASS---REDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKD 653
+R RE ++ RE+ P K RR + Y+++ ++ + R K
Sbjct: 1137 ERQYREEEEVQQEEEQLLREE--PEKRRRQELERQYREEEELQQE---EEQLLREEQEKR 1191
Query: 654 RHRRERSRERRGSASRKHSRHRRRSERSRS 683
R RER R+ + R R E RS
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Score = 73.6 bits (179), Expect = 6e-13
Identities = 59/209 (28%), Positives = 105/209 (50%), Gaps = 37/209 (17%)
Query: 268 IKKRQLER--QKLQELEQQR-EEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
+K+ Q ER Q+L+ E +R E+++RRE+ + + EER+Q+ L+ E+E +R+++LR+
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 325 REQKQRDRELRRNQ----------------KKLEKLQAEEQKQLQEKIK----------- 357
+Q++R++ L+R + ++ ++L EEQ+Q +E+IK
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
Query: 358 ----LEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAE 413
+ K+ R + R E + + + Q Q+EE+ QQQEE +R
Sbjct: 710 SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW 769
Query: 414 LRRVEEEKERA---LGLQRKERELRERLL 439
+ EE+ ER L + RE RER L
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQL 798
Score = 73.2 bits (178), Expect = 8e-13
Identities = 56/229 (24%), Positives = 125/229 (54%), Gaps = 21/229 (9%)
Query: 220 QYREYMGFIQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQ 279
Q R++M Q + G + + + D K + + + + +++ +R+ L+
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRK-----FREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 280 E----LEQQREEQKRREKEA---EERQRAEERKQKELEELERERKREEKLRKREQKQRDR 332
E Q+RE+Q R +++ EE Q +E ++++L ER+RK E+ ++ +++R+R
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 333 ELRRNQKKLEKLQAEEQKQLQEKIKLE-ERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
+ + +++L + + E + + +E+++ E E++ L Q + I +L + +LR Q
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Query: 392 E-----QKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELR 435
E ++EE+LR +++E++ R QE++ + EEE+ R +R+E++LR
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ---EREEQQLR 1813
Score = 71.6 bits (174), Expect = 2e-12
Identities = 59/188 (31%), Positives = 103/188 (54%), Gaps = 24/188 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK--------REE 320
+++QL RQ+ Q Q E+Q RR++ ++R++ +RK +E E+L +ER+ R+
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579
Query: 321 KLRKREQKQRDRELRR----NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI-RL 375
K R EQK R +E R ++++L + + ++Q + + K E + LL +R Q + R
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ 1639
Query: 376 IAELLSRAKAVKLREQEQKEEKLRLQQ----QEERRRLQEAE---LRRVEEE---KERAL 425
+ + +LR QE +E++LR + +EE + LQE E LRR E + +E
Sbjct: 1640 ERDRKFLEEEPQLRRQE-REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 426 GLQRKERE 433
L+R+ERE
Sbjct: 1699 QLRRQERE 1706
Score = 71.2 bits (173), Expect = 3e-12
Identities = 60/212 (28%), Positives = 110/212 (51%), Gaps = 41/212 (19%)
Query: 232 SALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRR 291
+A+R K+ KG + + + L D+ ++ +RQ Q+L+ EQ+ R
Sbjct: 1233 NAVRDNKVYCKGREN-----------EQFRQLEDSQLR----DRQSQQDLQHLLGEQQER 1277
Query: 292 EKEAEERQ-RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQK 350
++E E R+ + +R E E+LERE ++E K R R+ ++ +K+L + + EE++
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE--------EKQLLREEREEKR 1329
Query: 351 QLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQ-----E 404
+ QE K E + LL +R Q +R + R+++ +EE+LR Q+Q E
Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRR-----------QERDRKFREEELRHQEQGRKFLE 1378
Query: 405 ERRRLQEAELRRVEEEKERALGLQRKERELRE 436
E +RL+ E R ++E+ L Q +E++LR+
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Score = 71.2 bits (173), Expect = 3e-12
Identities = 55/188 (29%), Positives = 105/188 (55%), Gaps = 17/188 (9%)
Query: 269 KKRQLERQ------KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERE-RKREEK 321
+++QL RQ +L+E + +R+EQ+R+ E E++ R +E +Q+ +E +R+ R+ E+
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 322 LRKREQKQ-----RDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI-RL 375
L++RE++Q RDR+ + +L + + E+Q + K E + LL + Q + R
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 376 IAELLSRAKAVKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKE 431
+ R + +LR QE++ +E+ +L++QE R+ +E E R E E+E+ +R
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747
Query: 432 RELRERLL 439
+ L E L
Sbjct: 1748 KILEEEQL 1755
Score = 70.5 bits (171), Expect = 5e-12
Identities = 55/178 (30%), Positives = 104/178 (58%), Gaps = 13/178 (7%)
Query: 271 RQLERQKLQELEQQ--REEQKRREKEAEERQRAEERKQKELEELERERK-REEKLRKREQ 327
RQ +K +E EQQ R+E+ R+ +E E++ R +ER++K LEE ++ R+ R K R+ EQ
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 328 KQRDRE---LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRA 383
++RE L R ++ + L+ E+Q + QE+ K E++L + + + +L +
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 384 KAVKLREQEQ---KEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
+ K ++EQ ++E+ + ++Q+ R+ +E E R E E+++ L R+ER+ + RL
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ---LSRQERDRKFRL 1583
Score = 69.7 bits (169), Expect = 9e-12
Identities = 54/207 (26%), Positives = 108/207 (52%), Gaps = 21/207 (10%)
Query: 261 KHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREE 320
K L + +RQ +K + EQQ Q+R ++ ++R R ++++L ER+RK E
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434
Query: 321 KLRKREQKQRDRELRRNQKKLEKLQ----AEEQKQLQEKIKLEERKLLLAQRNLQSIRLI 376
+ ++ +++R+R+ +++L + + EE++ LQE+ EE++L +R+ + +
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER---EEQQLHRQERDRKFLEEE 1491
Query: 377 AELLSRAKAVKLREQE-----------QKEEKLRLQQQEERRRLQEAELRRVEEEKERAL 425
+L + + K REQE ++E++L QQ++ + +E +LRR E ++R
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Query: 426 GLQRK---ERELRERLLSILLSKKPDD 449
RK E +LR+ LS++ D
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERD 1578
Score = 68.9 bits (167), Expect = 1e-11
Identities = 51/193 (26%), Positives = 104/193 (53%), Gaps = 27/193 (13%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQR-------AEERKQKELEELERE----RK 317
++ + R++ EL+ Q EE+ R+++ EE++R AEE+ ++ + L +
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
Query: 318 REEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIA 377
RE +LR E++QR++ +++ E+ + + +++ +E LEE + L + Q ++
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRR----------LQE---AELRRVEEEKERA 424
+ L + + +++++++K R Q +EER+R LQE E + ++EE+E
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE- 912
Query: 425 LGLQRKERELRER 437
LQR+ERE R R
Sbjct: 913 --LQREEREKRRR 923
Score = 68.6 bits (166), Expect = 2e-11
Identities = 56/193 (29%), Positives = 112/193 (58%), Gaps = 23/193 (11%)
Query: 265 DASIKKRQLERQKLQELEQQ-REEQKRREKEAEERQRAEERKQK-ELEE-----LERERK 317
+ +++++ +Q+ Q+ +++ REE++ R++ E++ +ER +K LEE E+ERK
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 318 ---REEKLRKRE-----QKQRDRELRRNQKKLEKLQAEE-QKQLQEKIKLEERKLLLAQR 368
E++LR++E +++RDR+ R +++ L++ + ++ +Q +++ LEE L Q
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656
Query: 369 NLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEK-----ER 423
Q +R + R + L QE +E++LR Q+++ + R +E +LRR E E+ E+
Sbjct: 1657 REQQLRHDRDRKFREEEQLL--QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714
Query: 424 ALGLQRKERELRE 436
L Q ER+ RE
Sbjct: 1715 QLRRQELERKFRE 1727
Score = 68.2 bits (165), Expect = 2e-11
Identities = 60/206 (29%), Positives = 109/206 (52%), Gaps = 32/206 (15%)
Query: 261 KHLSDASIKKRQLERQKL-----------QELEQQREEQK-------RREKEAEERQRAE 302
K + D +RQ +Q+L ++L Q+REEQ+ R+ E E + R +
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Query: 303 ERKQKELEELERERKREEKLRKREQKQ------RDRELRRNQKKLEKLQAEEQKQLQEKI 356
ER+Q+ + +R+ + EE+L + ++Q RDR+ R +++L + Q E+K LQE+
Sbjct: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR-QERERKFLQEEQ 1714
Query: 357 KLEERKLLLAQRNLQSIRLIAE---LLSRAKAVKLREQEQ---KEEKLRLQQQEERRRLQ 410
+L ++L R + +R E L + + K+ E+EQ + E+ +L++QE R+ +
Sbjct: 1715 QLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFR 1774
Query: 411 EAELRRVEEEKERALGLQRKERELRE 436
E E R +E +E+ L Q +R+ RE
Sbjct: 1775 EEEQLR-QEREEQQLRSQESDRKFRE 1799
Score = 67.4 bits (163), Expect = 4e-11
Identities = 55/195 (28%), Positives = 108/195 (55%), Gaps = 20/195 (10%)
Query: 261 KHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREE 320
K L + +RQ +K +E E + +E +R+ E E++ ++R++K L+E E++ +R+E
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE-EQQLRRQE 1544
Query: 321 KLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE---KIKLEERKLLLAQRNLQSIRLIA 377
+ ++R Q RDR+ R +++L + + E+Q QE K +LEE+K+ ++ + +
Sbjct: 1545 RGQQRRQ-DRDRKFRE-EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 378 ELLSRAKAVKLRE-------------QEQKEEKLRLQQQEERRRLQEAELRRVEEEKERA 424
+L + +LR+ QE++E++L Q+++ + +E +LRR E E++
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 425 LGLQRKERELRERLL 439
RK RE E+LL
Sbjct: 1663 HDRDRKFRE-EEQLL 1676
Score = 65.9 bits (159), Expect = 1e-10
Identities = 45/176 (25%), Positives = 103/176 (58%), Gaps = 9/176 (5%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERK--QKELEELERERKREEKLRKRE 326
+++ L+ ++ Q+L +Q ++K E+E + R++ +RK ++EL E ERK E+ ++
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Query: 327 QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI-RLIAELLSRAKA 385
++QR R+ + +++L + + +Q++ K E + L +R Q + R + R +
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 386 VKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K+R QEQ+ E++ +L++QE +++L++ R+ E+++ L +R+E++L +
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ--LLQEREEQQLHRQ 1639
Score = 63.2 bits (152), Expect = 8e-10
Identities = 52/202 (25%), Positives = 108/202 (53%), Gaps = 33/202 (16%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA-----EERQR------AEERKQKELEELERERK 317
K+ +L++++ Q L ++ E+++R+E+E EE Q+ EER+++ +ELER+ +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 318 REEK--------LRKREQKQRDRELRRNQKKLEKLQAEEQKQL---QEKIKLEERKLLLA 366
EE+ LR+ +K+R +EL R ++ E+LQ EE++ L QEK + E +
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 367 QRNLQSIRLIAELLSRAKAVKLREQEQKEEK---------LRLQQQEERRRLQEAEL--R 415
+ LQ + + L+ Q + E++ + ++ E+ R+L++++L R
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 416 RVEEEKERALGLQRKERELRER 437
+ +++ + LG Q++ +ER
Sbjct: 1262 QSQQDLQHLLGEQQERDREQER 1283
Score = 62.4 bits (150), Expect = 1e-09
Identities = 56/215 (26%), Positives = 108/215 (50%), Gaps = 38/215 (17%)
Query: 269 KKRQLERQKLQELEQQ--REEQKRREKEAEERQRAEERKQKELEELERERKREE------ 320
+++QL R++ + EQ+ REE++ R ++ +R+ EER+++EL E E+E+ RE
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Query: 321 -------------------KLRKRE-QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEE 360
+ RK+E Q++R + + +++ +LQ +E+++ + + EE
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 361 RKLLLA---QRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAE---- 413
++ Q +S R L +R LREQ +++ + +QQ E+R L E E
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPP---LREQRERQLRAEERQQREQRFLPEEEEKEQ 819
Query: 414 LRRVEEEKERALGLQRKERELRERLLSILLSKKPD 448
RR E+E+ L +E +L+ R + L ++ D
Sbjct: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/180 (24%), Positives = 90/180 (50%), Gaps = 34/180 (18%)
Query: 286 EEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQ 345
+E +++ EE QR E + ++LEE +R+R+ +++EQ++ E +K E+L+
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ---KRQEQERELAEGEEQSEKQERLE 162
Query: 346 AEEQ--------KQLQEKIKLEERKLLLAQRNLQSI----------------RLIAELLS 381
++ +Q QE + EER+ + LQS R + EL
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERR--AEEEQLQSCKGHETEEFPDEEQLRRRELLELRR 220
Query: 382 RAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRR-----VEEEKERALGLQRKERELRE 436
+ + K +++ ++++++ +++E+ R +E LR+ EEE +R LQ +E +LR+
Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
Score = 38.9 bits (89), Expect = 0.016
Identities = 77/402 (19%), Positives = 149/402 (37%), Gaps = 69/402 (17%)
Query: 294 EAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQ 353
+ E+R R + + E L ++R++EE R+ E + R E Q++ +K Q E++++L
Sbjct: 96 DEEKRARCDGK-----ESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ-EQERELA 149
Query: 354 EKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAE 413
E +EQ E++ RL+Q++ +RR +E
Sbjct: 150 EG-----------------------------------EEQSEKQERLEQRDRQRRDEELW 174
Query: 414 LRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQT 473
+R E + +R+ER E L K + DE + +LL+
Sbjct: 175 RQRQEWQ-------EREERRAEEEQLQ--SCKGHETEEFPDEEQLRRRELLE-------- 217
Query: 474 VSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVP 533
+ Q +E + + + + EE P ++ R +
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ-----RELQ 272
Query: 534 EDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRK--DTRSEQDKCNREPSKGRGR-- 589
E+ ++ L +Q + EQ + RK + R EQ + RE + R +
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 590 ATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRS 649
+ R + ER + +E+ R ++ R ++ ++ RR + RR
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 650 HS--KDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRH 689
+++ R + RR R+ + RR + R + RH
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Score = 38.1 bits (87), Expect = 0.028
Identities = 28/123 (22%), Positives = 45/123 (36%), Gaps = 10/123 (8%)
Query: 573 RSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDD 632
R E++K E + R R + K ER RR E+ + ++ RR +
Sbjct: 254 RKEEEKLQEEEPQ-RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR---------E 303
Query: 633 SPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRST 692
RR + + + + RRE+ ERR R+ RR + R + R
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 693 WNR 695
R
Sbjct: 364 LRR 366
Score = 36.6 bits (83), Expect = 0.081
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 9/131 (6%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
E+ RK R E + +E + + R + R + E R ++ RE R+++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRH----RRERSRERRGSASRKHSRHRRRSE 679
++ + + RR + RR ++R RRE+ ERR R+ + RR +
Sbjct: 334 RREQQLRREQEERREQ-----QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 680 RSRSRSPSRHR 690
R + R +
Sbjct: 389 LRREQQLRREQ 399
Score = 36.6 bits (83), Expect = 0.081
Identities = 27/133 (20%), Positives = 51/133 (38%), Gaps = 8/133 (6%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
EQ + R+ + + RE + R + +RE+ R R + + R+E++
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 624 HKKHAYKDDSPRRRSTSPDHTRS-------RRSHSKDRHRRERSRERRGSASRKHSRHRR 676
++ + + RR + RR ++RH ++ +ERR K + R
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR-EQRLKREQEER 454
Query: 677 RSERSRSRSPSRH 689
R R RH
Sbjct: 455 RDWLKREEETERH 467
Score = 36.2 bits (82), Expect = 0.11
Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 16/136 (11%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASS-----REDGRPR 618
+Q + R+ + + RE + R L R KRE RR +E R R
Sbjct: 644 QQQLRREQQERREQRLKREEEEER-------LEQRLKREHEEERREQELAEEEQEQARER 696
Query: 619 -KERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRR 677
K R P + + ++ R+S ++R R+ + R R+E+ +RR S + R
Sbjct: 697 IKSRIPKWQWQLESEADARQSKV--YSRPRKQEGQ-RRRQEQEEKRRRRESELQWQEEER 753
Query: 678 SERSRSRSPSRHRSTW 693
+ R + R TW
Sbjct: 754 AHRQQQEEEQRRDFTW 769
Score = 35.0 bits (79), Expect = 0.23
Identities = 19/74 (25%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Query: 261 KHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREE 320
++ ++ ++ R++ QEL Q+ E+++R+E+E + R+ R+QKE E+ ++
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE----EQRHRQVG 1899
Query: 321 KLRKREQKQRDREL 334
+++ +E K R L
Sbjct: 1900 EIKSQEGKGHGRLL 1913
Score = 33.9 bits (76), Expect = 0.52
Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 19/142 (13%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
E R+ R EQ+ RE ++G ++ ++ R+R R++ + R+ERR
Sbjct: 132 EPGQRRRQKRQEQE---RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188
Query: 624 ----------HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRER-----SRERRGSAS 668
H+ + D+ RR + R R K + RRER E
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR-EEKQQQRRERQDRVFQEEEEKEWR 247
Query: 669 RKHSRHRRRSERSRSRSPSRHR 690
++ + R+ E+ + P R R
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQR 269
Score = 33.5 bits (75), Expect = 0.68
Identities = 24/125 (19%), Positives = 44/125 (35%), Gaps = 7/125 (5%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
EQ + R+ + + RE + R +H++ER R +E+ R +R
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHE-------QKHEQERREQRLKREQEERRDWLKREE 462
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRS 683
+ ++ ++ + R R + R +ERR R+ RR R
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 684 RSPSR 688
R
Sbjct: 523 EEEER 527
Score = 33.5 bits (75), Expect = 0.68
Identities = 24/129 (18%), Positives = 50/129 (38%), Gaps = 4/129 (3%)
Query: 564 EQNVSRKDTRSEQDK----CNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRK 619
EQ R + + EQ++ RE + R + +RH++ER + + +E+ R +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 620 ERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSE 679
+ ++ + R + + R K + ER ++R S + R E
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 680 RSRSRSPSR 688
+ R +
Sbjct: 548 QLLKREEEK 556
Score = 32.3 bits (72), Expect = 1.5
Identities = 20/119 (16%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
++ +++ R EQ + RE + R + + + ++ R + R + + R+E++
Sbjct: 325 QERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSR 682
++ + + RR + R + R ++ RE++ ++ RH ++ E+ R
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Score = 31.6 bits (70), Expect = 2.6
Identities = 21/106 (19%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 594 GLADRHKRERSRARRASSREDGRPRKERRP---HKKHAYKDDSPRRRSTSPDHTRSRRSH 650
G ++ ++ R R R E+ + ++R ++ +++ P+R+ + R
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 651 SKDRHRRER-SRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
+ RRER E++ R+ + RR+ E R R R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Score = 31.2 bits (69), Expect = 3.4
Identities = 28/147 (19%), Positives = 60/147 (40%), Gaps = 12/147 (8%)
Query: 550 IPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRA 609
+ + +Q + + E R++ +Q + RE R + +R +++ R +
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE-----ERREQQEERREQQ 325
Query: 610 SSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRS--RRSHSKDRH----RRERSRER 663
RE R+E++ ++ + + RR + RR ++R RRE+ + R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ-QLR 384
Query: 664 RGSASRKHSRHRRRSERSRSRSPSRHR 690
R R+ + RR + R + R +
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQ 411
Score = 31.2 bits (69), Expect = 3.4
Identities = 29/139 (20%), Positives = 50/139 (35%), Gaps = 16/139 (11%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
EQ + R+ + + RE R + +RE+ R R + + R+E+
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQL--------RREQQLRREQQLRREQQLRREQE- 430
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSK-----DRHRRERSRE--RRGSASRKHSRHRR 676
++H K + RR RR K +RH +ER ++ +R + R +
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 677 RSERSRSRSPSRHRSTWNR 695
E R R R
Sbjct: 491 LEEEERREQQERREQQLRR 509
Score = 30.4 bits (67), Expect = 5.8
Identities = 27/121 (22%), Positives = 42/121 (34%), Gaps = 5/121 (4%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDG---LADRHKRER-SRARRASSREDGRPRK 619
EQ + R+ RE + + R + L R KRE R + RE R+
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Query: 620 ERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRER-RGSASRKHSRHRRRS 678
E ++ + R ++ + R +RE ER R+H RR
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 679 E 679
E
Sbjct: 684 E 684
Score = 30.4 bits (67), Expect = 5.8
Identities = 19/93 (20%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Query: 598 RHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRR 657
RH R+R ++G ++ RR + ++++ + R R R+ +++ R
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR----QERERKFLQEEQQLR 1717
Query: 658 ERSRERRGSASRKHSRHRRRSERSRSRSPSRHR 690
+ ER+ R+ + R+ +E+ + R R+R
Sbjct: 1718 RQELERK---FREEEQLRQETEQEQLRRQERYR 1747
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/180 (33%), Positives = 104/180 (57%), Gaps = 12/180 (6%)
Query: 271 RQLERQKLQELEQQREEQK---RREKEAEERQRAEERKQKEL----EELERERKREEKLR 323
+QLE+ K +LEQ+R E + +RE+E +RQ R+Q+E+ +E ER+R+ EE+L
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI--KLEERKLLLAQRNLQSIRLIAELLS 381
+R+Q++ R R + L + + EE++Q QE+ +LEER+ +R Q L +
Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840
Query: 382 RAKAVKLREQEQK---EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
AK + E+ Q+ E +LR++++ R R +E E +R E E +R L R+ ++ +E L
Sbjct: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900
Score = 82.8 bits (203), Expect = 1e-15
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 59/228 (25%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE-----------RKQKELE------- 310
K+ + ER++ +EL +Q+EE RR++E E ++R EE R+Q+E E
Sbjct: 743 KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 802
Query: 311 ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEE-----------QKQLQE-KIKL 358
E E +++EE LR+ E+++R+ E RR Q++L + Q EE Q++L+E ++++
Sbjct: 803 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 862
Query: 359 EERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE------- 411
EE L + R E + R K + + Q+Q+E RLQQQ+++++L +
Sbjct: 863 EEEAARLRHEEEERKRKELE-VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
Query: 412 -------------------AELRRVEEEKERAL--GLQRKERELRERL 438
AE++++EEE+ER L +R++REL + L
Sbjct: 922 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 969
Score = 70.9 bits (172), Expect = 4e-12
Identities = 53/171 (30%), Positives = 99/171 (57%), Gaps = 18/171 (10%)
Query: 271 RQLERQKLQELEQQREEQ--KRREKEAEERQRAEERKQKELEE----LERERKR-----E 319
R+LE ++ +E E++++E+ +++E+EA + R EE Q+ LEE +E E R E
Sbjct: 815 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
Query: 320 EKLRKREQKQRDRELRR----NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRL 375
E+ RK + QR +EL R Q+ L +LQ ++Q+Q ++KL Q N + +
Sbjct: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934
Query: 376 IAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALG 426
A LS A+ KL +E++E +LR +Q+ ++R L +A ++ ++++++ G
Sbjct: 935 QA-TLSLAEIQKL--EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 982
Score = 70.5 bits (171), Expect = 5e-12
Identities = 47/138 (34%), Positives = 78/138 (56%), Gaps = 16/138 (11%)
Query: 296 EERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
E+ Q+ E+ K +LE+ RE + K R+ E+++R ELRR Q+++ + Q EE+++ +E+
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEILRRQQEEERKRREE 776
Query: 356 IKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR 415
+L RK E L R + ++ + Q+EE+ R QQ+E RRL+E R
Sbjct: 777 EELARRKQ-------------EEALRRQREQEIALRRQREEEERQQQEEALRRLEER--R 821
Query: 416 RVEEEKERALGLQRKERE 433
R EEE+ + L RK+ E
Sbjct: 822 REEEERRKQEELLRKQEE 839
Score = 63.2 bits (152), Expect = 8e-10
Identities = 42/130 (32%), Positives = 77/130 (59%), Gaps = 10/130 (7%)
Query: 309 LEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQR 368
LE+L++ K K K EQ++R+ E+R ++ EE+++ QE+++ ++ ++L Q+
Sbjct: 717 LEQLQQLEKA--KAAKLEQERREAEMRAKRE-------EEERKRQEELRRQQEEILRRQQ 767
Query: 369 NLQSIRLIAELLSRAKAVK-LREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGL 427
+ R E L+R K + LR Q ++E LR Q++EE R+ QE LRR+EE +
Sbjct: 768 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 827
Query: 428 QRKERELRER 437
+++E LR++
Sbjct: 828 RKQEELLRKQ 837
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/151 (18%), Positives = 81/151 (53%), Gaps = 7/151 (4%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
+A+ + + E +K +ELE QR+++ R+++ ++ ++Q++ ++L + +
Sbjct: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 924
Query: 325 REQKQR--DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLA-----QRNLQSIRLIA 377
++ + + +++KL+ E ++QL+E+ + ++R+L+ A Q+ Q +
Sbjct: 925 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWG 984
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
+ + K + Q+EE ++Q+Q+++++
Sbjct: 985 NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1015
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 44/166 (26%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQK--------------------- 307
K+++LE Q+ +EL +QR++Q+ + +++Q+ ++ Q
Sbjct: 877 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 936
Query: 308 -----ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
E+++LE ER+R+ + EQ+++ REL ++ LQ ++Q+Q Q+
Sbjct: 937 TLSLAEIQKLEEERERQ---LREEQRRQQREL------MKALQQQQQQQQQK-------- 979
Query: 363 LLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
L N+ + L + + R+ ++++++ + QQ R R
Sbjct: 980 -LSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1024
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 11/106 (10%)
Query: 350 KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRL 409
+QLQ+ K + KL +R + +A + E+ +++E+LR QQ+E RR
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEM-----------RAKREEEERKRQEELRRQQEEILRRQ 766
Query: 410 QEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
QE E +R EEE+ + R RE+ +++ ++ ++ +E
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Score = 34.7 bits (78), Expect = 0.31
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 28/110 (25%)
Query: 243 GEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKE----AEER 298
G+ AC + + LS A I+K + ER++ Q REEQ+R+++E +++
Sbjct: 924 GQQSNTTACQSQAT------LSLAEIQKLEEERER-----QLREEQRRQQRELMKALQQQ 972
Query: 299 QRAEERK-------------QKELEELERERKREEKLRKREQKQRDRELR 335
Q+ +++K K L E+++E R+ + ++++Q+Q + R
Sbjct: 973 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1022
Score = 33.5 bits (75), Expect = 0.68
Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 596 ADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRH 655
A R + ER R +++ R+++ +K +++ RR+ + + + R
Sbjct: 742 AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQ 801
Query: 656 RRERSRERRGSASRKHSRHRRRSERSRSR 684
R E R+++ A R+ RRR E R +
Sbjct: 802 REEEERQQQEEALRR-LEERRREEEERRK 829
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/180 (33%), Positives = 104/180 (57%), Gaps = 12/180 (6%)
Query: 271 RQLERQKLQELEQQREEQK---RREKEAEERQRAEERKQKEL----EELERERKREEKLR 323
+QLE+ K +LEQ+R E + +RE+E +RQ R+Q+E+ +E ER+R+ EE+L
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI--KLEERKLLLAQRNLQSIRLIAELLS 381
+R+Q++ R R + L + + EE++Q QE+ +LEER+ +R Q L +
Sbjct: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 867
Query: 382 RAKAVKLREQEQK---EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
AK + E+ Q+ E +LR++++ R R +E E +R E E +R L R+ ++ +E L
Sbjct: 868 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 927
Score = 82.8 bits (203), Expect = 1e-15
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 59/228 (25%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE-----------RKQKELE------- 310
K+ + ER++ +EL +Q+EE RR++E E ++R EE R+Q+E E
Sbjct: 770 KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 829
Query: 311 ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEE-----------QKQLQE-KIKL 358
E E +++EE LR+ E+++R+ E RR Q++L + Q EE Q++L+E ++++
Sbjct: 830 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 889
Query: 359 EERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE------- 411
EE L + R E + R K + + Q+Q+E RLQQQ+++++L +
Sbjct: 890 EEEAARLRHEEEERKRKELE-VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
Query: 412 -------------------AELRRVEEEKERAL--GLQRKERELRERL 438
AE++++EEE+ER L +R++REL + L
Sbjct: 949 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 996
Score = 70.9 bits (172), Expect = 4e-12
Identities = 53/171 (30%), Positives = 99/171 (57%), Gaps = 18/171 (10%)
Query: 271 RQLERQKLQELEQQREEQ--KRREKEAEERQRAEERKQKELEE----LERERKR-----E 319
R+LE ++ +E E++++E+ +++E+EA + R EE Q+ LEE +E E R E
Sbjct: 842 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
Query: 320 EKLRKREQKQRDRELRR----NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRL 375
E+ RK + QR +EL R Q+ L +LQ ++Q+Q ++KL Q N + +
Sbjct: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961
Query: 376 IAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALG 426
A LS A+ KL +E++E +LR +Q+ ++R L +A ++ ++++++ G
Sbjct: 962 QA-TLSLAEIQKL--EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 1009
Score = 70.5 bits (171), Expect = 5e-12
Identities = 47/138 (34%), Positives = 78/138 (56%), Gaps = 16/138 (11%)
Query: 296 EERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
E+ Q+ E+ K +LE+ RE + K R+ E+++R ELRR Q+++ + Q EE+++ +E+
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEILRRQQEEERKRREE 803
Query: 356 IKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR 415
+L RK E L R + ++ + Q+EE+ R QQ+E RRL+E R
Sbjct: 804 EELARRKQ-------------EEALRRQREQEIALRRQREEEERQQQEEALRRLEER--R 848
Query: 416 RVEEEKERALGLQRKERE 433
R EEE+ + L RK+ E
Sbjct: 849 REEEERRKQEELLRKQEE 866
Score = 63.2 bits (152), Expect = 8e-10
Identities = 42/130 (32%), Positives = 77/130 (59%), Gaps = 10/130 (7%)
Query: 309 LEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQR 368
LE+L++ K K K EQ++R+ E+R ++ EE+++ QE+++ ++ ++L Q+
Sbjct: 744 LEQLQQLEKA--KAAKLEQERREAEMRAKRE-------EEERKRQEELRRQQEEILRRQQ 794
Query: 369 NLQSIRLIAELLSRAKAVK-LREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGL 427
+ R E L+R K + LR Q ++E LR Q++EE R+ QE LRR+EE +
Sbjct: 795 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 854
Query: 428 QRKERELRER 437
+++E LR++
Sbjct: 855 RKQEELLRKQ 864
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/151 (18%), Positives = 81/151 (53%), Gaps = 7/151 (4%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
+A+ + + E +K +ELE QR+++ R+++ ++ ++Q++ ++L + +
Sbjct: 892 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 951
Query: 325 REQKQR--DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLA-----QRNLQSIRLIA 377
++ + + +++KL+ E ++QL+E+ + ++R+L+ A Q+ Q +
Sbjct: 952 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWG 1011
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
+ + K + Q+EE ++Q+Q+++++
Sbjct: 1012 NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1042
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 44/166 (26%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQK--------------------- 307
K+++LE Q+ +EL +QR++Q+ + +++Q+ ++ Q
Sbjct: 904 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 963
Query: 308 -----ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
E+++LE ER+R+ + EQ+++ REL ++ LQ ++Q+Q Q+
Sbjct: 964 TLSLAEIQKLEEERERQ---LREEQRRQQREL------MKALQQQQQQQQQK-------- 1006
Query: 363 LLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
L N+ + L + + R+ ++++++ + QQ R R
Sbjct: 1007 -LSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1051
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 11/106 (10%)
Query: 350 KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRL 409
+QLQ+ K + KL +R + +A + E+ +++E+LR QQ+E RR
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEM-----------RAKREEEERKRQEELRRQQEEILRRQ 793
Query: 410 QEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
QE E +R EEE+ + R RE+ +++ ++ ++ +E
Sbjct: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
Score = 34.7 bits (78), Expect = 0.31
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 28/110 (25%)
Query: 243 GEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKE----AEER 298
G+ AC + + LS A I+K + ER++ Q REEQ+R+++E +++
Sbjct: 951 GQQSNTTACQSQAT------LSLAEIQKLEEERER-----QLREEQRRQQRELMKALQQQ 999
Query: 299 QRAEERK-------------QKELEELERERKREEKLRKREQKQRDRELR 335
Q+ +++K K L E+++E R+ + ++++Q+Q + R
Sbjct: 1000 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1049
Score = 33.5 bits (75), Expect = 0.68
Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 596 ADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRH 655
A R + ER R +++ R+++ +K +++ RR+ + + + R
Sbjct: 769 AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQ 828
Query: 656 RRERSRERRGSASRKHSRHRRRSERSRSR 684
R E R+++ A R+ RRR E R +
Sbjct: 829 REEEERQQQEEALRR-LEERRREEEERRK 856
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/180 (33%), Positives = 104/180 (57%), Gaps = 12/180 (6%)
Query: 271 RQLERQKLQELEQQREEQK---RREKEAEERQRAEERKQKEL----EELERERKREEKLR 323
+QLE+ K +LEQ+R E + +RE+E +RQ R+Q+E+ +E ER+R+ EE+L
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI--KLEERKLLLAQRNLQSIRLIAELLS 381
+R+Q++ R R + L + + EE++Q QE+ +LEER+ +R Q L +
Sbjct: 787 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846
Query: 382 RAKAVKLREQEQK---EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
AK + E+ Q+ E +LR++++ R R +E E +R E E +R L R+ ++ +E L
Sbjct: 847 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 906
Score = 82.8 bits (203), Expect = 1e-15
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 59/228 (25%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE-----------RKQKELE------- 310
K+ + ER++ +EL +Q+EE RR++E E ++R EE R+Q+E E
Sbjct: 749 KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 808
Query: 311 ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEE-----------QKQLQE-KIKL 358
E E +++EE LR+ E+++R+ E RR Q++L + Q EE Q++L+E ++++
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 868
Query: 359 EERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE------- 411
EE L + R E + R K + + Q+Q+E RLQQQ+++++L +
Sbjct: 869 EEEAARLRHEEEERKRKELE-VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Query: 412 -------------------AELRRVEEEKERAL--GLQRKERELRERL 438
AE++++EEE+ER L +R++REL + L
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
Score = 70.9 bits (172), Expect = 4e-12
Identities = 53/171 (30%), Positives = 99/171 (57%), Gaps = 18/171 (10%)
Query: 271 RQLERQKLQELEQQREEQ--KRREKEAEERQRAEERKQKELEE----LERERKR-----E 319
R+LE ++ +E E++++E+ +++E+EA + R EE Q+ LEE +E E R E
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 320 EKLRKREQKQRDRELRR----NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRL 375
E+ RK + QR +EL R Q+ L +LQ ++Q+Q ++KL Q N + +
Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
Query: 376 IAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALG 426
A LS A+ KL +E++E +LR +Q+ ++R L +A ++ ++++++ G
Sbjct: 941 QA-TLSLAEIQKL--EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 988
Score = 70.5 bits (171), Expect = 5e-12
Identities = 47/138 (34%), Positives = 78/138 (56%), Gaps = 16/138 (11%)
Query: 296 EERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
E+ Q+ E+ K +LE+ RE + K R+ E+++R ELRR Q+++ + Q EE+++ +E+
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEILRRQQEEERKRREE 782
Query: 356 IKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR 415
+L RK E L R + ++ + Q+EE+ R QQ+E RRL+E R
Sbjct: 783 EELARRKQ-------------EEALRRQREQEIALRRQREEEERQQQEEALRRLEER--R 827
Query: 416 RVEEEKERALGLQRKERE 433
R EEE+ + L RK+ E
Sbjct: 828 REEEERRKQEELLRKQEE 845
Score = 63.2 bits (152), Expect = 8e-10
Identities = 42/130 (32%), Positives = 77/130 (59%), Gaps = 10/130 (7%)
Query: 309 LEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQR 368
LE+L++ K K K EQ++R+ E+R ++ EE+++ QE+++ ++ ++L Q+
Sbjct: 723 LEQLQQLEKA--KAAKLEQERREAEMRAKRE-------EEERKRQEELRRQQEEILRRQQ 773
Query: 369 NLQSIRLIAELLSRAKAVK-LREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGL 427
+ R E L+R K + LR Q ++E LR Q++EE R+ QE LRR+EE +
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
Query: 428 QRKERELRER 437
+++E LR++
Sbjct: 834 RKQEELLRKQ 843
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/151 (18%), Positives = 81/151 (53%), Gaps = 7/151 (4%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
+A+ + + E +K +ELE QR+++ R+++ ++ ++Q++ ++L + +
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 930
Query: 325 REQKQR--DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLA-----QRNLQSIRLIA 377
++ + + +++KL+ E ++QL+E+ + ++R+L+ A Q+ Q +
Sbjct: 931 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWG 990
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
+ + K + Q+EE ++Q+Q+++++
Sbjct: 991 NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1021
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 44/166 (26%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQK--------------------- 307
K+++LE Q+ +EL +QR++Q+ + +++Q+ ++ Q
Sbjct: 883 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 942
Query: 308 -----ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
E+++LE ER+R+ + EQ+++ REL ++ LQ ++Q+Q Q+
Sbjct: 943 TLSLAEIQKLEEERERQ---LREEQRRQQREL------MKALQQQQQQQQQK-------- 985
Query: 363 LLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
L N+ + L + + R+ ++++++ + QQ R R
Sbjct: 986 -LSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1030
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 11/106 (10%)
Query: 350 KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRL 409
+QLQ+ K + KL +R + +A + E+ +++E+LR QQ+E RR
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEM-----------RAKREEEERKRQEELRRQQEEILRRQ 772
Query: 410 QEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
QE E +R EEE+ + R RE+ +++ ++ ++ +E
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Score = 34.7 bits (78), Expect = 0.31
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 28/110 (25%)
Query: 243 GEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKE----AEER 298
G+ AC + + LS A I+K + ER++ Q REEQ+R+++E +++
Sbjct: 930 GQQSNTTACQSQAT------LSLAEIQKLEEERER-----QLREEQRRQQRELMKALQQQ 978
Query: 299 QRAEERK-------------QKELEELERERKREEKLRKREQKQRDRELR 335
Q+ +++K K L E+++E R+ + ++++Q+Q + R
Sbjct: 979 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
Score = 33.5 bits (75), Expect = 0.68
Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 596 ADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRH 655
A R + ER R +++ R+++ +K +++ RR+ + + + R
Sbjct: 748 AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQ 807
Query: 656 RRERSRERRGSASRKHSRHRRRSERSRSR 684
R E R+++ A R+ RRR E R +
Sbjct: 808 REEEERQQQEEALRR-LEERRREEEERRK 835
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/180 (33%), Positives = 104/180 (57%), Gaps = 12/180 (6%)
Query: 271 RQLERQKLQELEQQREEQK---RREKEAEERQRAEERKQKEL----EELERERKREEKLR 323
+QLE+ K +LEQ+R E + +RE+E +RQ R+Q+E+ +E ER+R+ EE+L
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI--KLEERKLLLAQRNLQSIRLIAELLS 381
+R+Q++ R R + L + + EE++Q QE+ +LEER+ +R Q L +
Sbjct: 787 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846
Query: 382 RAKAVKLREQEQK---EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
AK + E+ Q+ E +LR++++ R R +E E +R E E +R L R+ ++ +E L
Sbjct: 847 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 906
Score = 82.8 bits (203), Expect = 1e-15
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 59/228 (25%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE-----------RKQKELE------- 310
K+ + ER++ +EL +Q+EE RR++E E ++R EE R+Q+E E
Sbjct: 749 KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 808
Query: 311 ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEE-----------QKQLQE-KIKL 358
E E +++EE LR+ E+++R+ E RR Q++L + Q EE Q++L+E ++++
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 868
Query: 359 EERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE------- 411
EE L + R E + R K + + Q+Q+E RLQQQ+++++L +
Sbjct: 869 EEEAARLRHEEEERKRKELE-VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Query: 412 -------------------AELRRVEEEKERAL--GLQRKERELRERL 438
AE++++EEE+ER L +R++REL + L
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
Score = 70.9 bits (172), Expect = 4e-12
Identities = 53/171 (30%), Positives = 99/171 (57%), Gaps = 18/171 (10%)
Query: 271 RQLERQKLQELEQQREEQ--KRREKEAEERQRAEERKQKELEE----LERERKR-----E 319
R+LE ++ +E E++++E+ +++E+EA + R EE Q+ LEE +E E R E
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 320 EKLRKREQKQRDRELRR----NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRL 375
E+ RK + QR +EL R Q+ L +LQ ++Q+Q ++KL Q N + +
Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
Query: 376 IAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALG 426
A LS A+ KL +E++E +LR +Q+ ++R L +A ++ ++++++ G
Sbjct: 941 QA-TLSLAEIQKL--EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 988
Score = 70.5 bits (171), Expect = 5e-12
Identities = 47/138 (34%), Positives = 78/138 (56%), Gaps = 16/138 (11%)
Query: 296 EERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
E+ Q+ E+ K +LE+ RE + K R+ E+++R ELRR Q+++ + Q EE+++ +E+
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEILRRQQEEERKRREE 782
Query: 356 IKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR 415
+L RK E L R + ++ + Q+EE+ R QQ+E RRL+E R
Sbjct: 783 EELARRKQ-------------EEALRRQREQEIALRRQREEEERQQQEEALRRLEER--R 827
Query: 416 RVEEEKERALGLQRKERE 433
R EEE+ + L RK+ E
Sbjct: 828 REEEERRKQEELLRKQEE 845
Score = 63.2 bits (152), Expect = 8e-10
Identities = 42/130 (32%), Positives = 77/130 (59%), Gaps = 10/130 (7%)
Query: 309 LEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQR 368
LE+L++ K K K EQ++R+ E+R ++ EE+++ QE+++ ++ ++L Q+
Sbjct: 723 LEQLQQLEKA--KAAKLEQERREAEMRAKRE-------EEERKRQEELRRQQEEILRRQQ 773
Query: 369 NLQSIRLIAELLSRAKAVK-LREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGL 427
+ R E L+R K + LR Q ++E LR Q++EE R+ QE LRR+EE +
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
Query: 428 QRKERELRER 437
+++E LR++
Sbjct: 834 RKQEELLRKQ 843
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/151 (18%), Positives = 81/151 (53%), Gaps = 7/151 (4%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
+A+ + + E +K +ELE QR+++ R+++ ++ ++Q++ ++L + +
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 930
Query: 325 REQKQR--DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLA-----QRNLQSIRLIA 377
++ + + +++KL+ E ++QL+E+ + ++R+L+ A Q+ Q +
Sbjct: 931 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWG 990
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
+ + K + Q+EE ++Q+Q+++++
Sbjct: 991 NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1021
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 44/166 (26%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQK--------------------- 307
K+++LE Q+ +EL +QR++Q+ + +++Q+ ++ Q
Sbjct: 883 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 942
Query: 308 -----ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
E+++LE ER+R+ + EQ+++ REL ++ LQ ++Q+Q Q+
Sbjct: 943 TLSLAEIQKLEEERERQ---LREEQRRQQREL------MKALQQQQQQQQQK-------- 985
Query: 363 LLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
L N+ + L + + R+ ++++++ + QQ R R
Sbjct: 986 -LSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1030
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 11/106 (10%)
Query: 350 KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRL 409
+QLQ+ K + KL +R + +A + E+ +++E+LR QQ+E RR
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEM-----------RAKREEEERKRQEELRRQQEEILRRQ 772
Query: 410 QEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
QE E +R EEE+ + R RE+ +++ ++ ++ +E
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Score = 34.7 bits (78), Expect = 0.31
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 28/110 (25%)
Query: 243 GEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKE----AEER 298
G+ AC + + LS A I+K + ER++ Q REEQ+R+++E +++
Sbjct: 930 GQQSNTTACQSQAT------LSLAEIQKLEEERER-----QLREEQRRQQRELMKALQQQ 978
Query: 299 QRAEERK-------------QKELEELERERKREEKLRKREQKQRDRELR 335
Q+ +++K K L E+++E R+ + ++++Q+Q + R
Sbjct: 979 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
Score = 33.5 bits (75), Expect = 0.68
Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 596 ADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRH 655
A R + ER R +++ R+++ +K +++ RR+ + + + R
Sbjct: 748 AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQ 807
Query: 656 RRERSRERRGSASRKHSRHRRRSERSRSR 684
R E R+++ A R+ RRR E R +
Sbjct: 808 REEEERQQQEEALRR-LEERRREEEERRK 835
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 87.8 bits (216), Expect = 3e-17
Identities = 54/173 (31%), Positives = 103/173 (59%), Gaps = 7/173 (4%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERE----RKREEKLRK 324
+KR+ ER+K ++ E+ ++E+K+R+K ++R +RK++E + ER RKR+++ +K
Sbjct: 44 EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKK 103
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
RE+KQR R R+ +K+ ++ + E +++ + K K +K +R + R E + K
Sbjct: 104 RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE--RKRK 161
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K E+E+K E+ R ++++ER R + E R+ E +KER +RK+ +R
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRE-RKKERKKERRKKKERKKDRKTDR 213
Score = 74.7 bits (182), Expect = 3e-13
Identities = 43/171 (25%), Positives = 102/171 (59%), Gaps = 16/171 (9%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELE----RERKREEKLRK 324
KK++ +R++ +E E++R+E++++ KE E++R + +K+K+ E + RERK++++ ++
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
RE++ + R R+ +K+ +K + +E+K+ +E+ K E ++ + + R R +
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR------ERNR 176
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELR 435
+ +E+E+KE + R +++++ RR ++ E +K+R Q + R
Sbjct: 177 KERKKERERKERRERKKERKKERR------KKKERKKDRKTDRQTDSQVFR 221
Score = 65.9 bits (159), Expect = 1e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 8/128 (6%)
Query: 561 PACEQNVSRKDTRSEQDKCNREPSKGRGRATGDG-LADRHKRERSRARRASSREDGRPRK 619
P ++ RK R E++K RE K R R G R KRER + R +E + RK
Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
Query: 620 ERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHR---R 676
ERR ++ K + +R R RR K + R+ER RE + RK + R R
Sbjct: 88 ERREKERRKRKKEKKKRERKQ----RGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
Query: 677 RSERSRSR 684
R ER R +
Sbjct: 144 RKERKREK 151
Score = 52.4 bits (124), Expect = 1e-06
Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 570 KDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAY 629
K+ R + + + K RGR +R +RER +R + R +K+RR +K
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR-- 149
Query: 630 KDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRH 689
+ + +R + R ++R+R+ER +ER R+ + R++ ER + + +
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK-ERRKKKERKKD 208
Query: 690 RST 692
R T
Sbjct: 209 RKT 211
Score = 46.6 bits (109), Expect = 8e-05
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Query: 597 DRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR 656
+R KR+R R + R+ R +KE++ KK + R+R + RR + + +
Sbjct: 42 EREKRKREREK---ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 657 RE---RSRERRGSASRKHSRHRRRSERSRSRSPSRHR 690
+E R R++RG RK + R+ ER + R R
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 15/107 (14%)
Query: 597 DRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR 656
+R +RE+ + R R+ R +KE++ KK + R+R + R K+R
Sbjct: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-------KEREKQRKERRE 91
Query: 657 RER--------SRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
+ER RER+ R+ + + R ER R R R R
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
Query: 596 ADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDR- 654
++R K R R +R RE R R+ + KK ++R + R R+ K R
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKR------KKRERGKERERKRKEREKQRK 87
Query: 655 HRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
RRE+ R +R +K R +R + + + R N+
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 604 SRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDH--TRSRRSHSKDRHRRERSR 661
S + ++ + +KERR +K + + R+R R +R K+R R+ + R
Sbjct: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER 82
Query: 662 ERRGSASRKHSRHRRRSERSRSRSPSRHR 690
E++ R+ R +R+ E+ + R R
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGR 111
Score = 33.9 bits (76), Expect = 0.52
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRER-----SRARRASSREDGRPR 618
E R+ R ++ K R + R + G R KR++ R R R+ R R
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 619 KERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSK 652
KERR KK K + +++ D R++ S+
Sbjct: 186 KERRERKKER-KKERRKKKERKKDRKTDRQTDSQ 218
Score = 33.5 bits (75), Expect = 0.68
Identities = 30/124 (24%), Positives = 49/124 (39%), Gaps = 17/124 (13%)
Query: 573 RSEQDKCNREPSKGRGRATGDGLADRHKRER-SRARRASSREDGRPRKERRPHKKHAYKD 631
R ++K RE + + R + ++ER R R+ R+ K+R ++K K+
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKE 182
Query: 632 DSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRS 691
R + ++ER +ERR RK R R S+ P R S
Sbjct: 183 ---------------RERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLR-ES 226
Query: 692 TWNR 695
+NR
Sbjct: 227 AFNR 230
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 83.6 bits (205), Expect = 6e-16
Identities = 61/206 (29%), Positives = 120/206 (58%), Gaps = 17/206 (8%)
Query: 243 GEDGKAVACNIKVSFDSTK---HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
G++ ++V+ ++ + + L+ +K + +K+QE E++ +EQ+ + +E EE+
Sbjct: 259 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM 318
Query: 300 RAEERKQKELEELERER-----KREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE 354
R +E E EE R + ++EEK+R+ E+K ++E R Q+ EK Q EE+ + QE
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE--EKRQEEEKIREQE 376
Query: 355 KIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEA 412
K + +E K+ R + IR E + R + ++EQE+K E++ ++ +QEE + QE
Sbjct: 377 KRQEQEAKM---WRQEEKIREQEEKI-REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 413 ELRRVEEE-KERALGLQRKERELRER 437
++RR EE+ +E+ ++ +E ++RE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQ 458
Score = 80.9 bits (198), Expect = 4e-15
Identities = 54/179 (30%), Positives = 118/179 (65%), Gaps = 19/179 (10%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAE--ERQRAEERKQKELEELERERKREEKLRKRE 326
K R+LE +K+ E E+ RE++++R++E + E+++ +E++ K + E+ R++EEK+R++E
Sbjct: 345 KIRELE-EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 327 QKQRDRELRRNQKKLEKL--QAEEQKQLQEKIKLEERKLLLAQRNL----QSIRLIAELL 380
+ +++E + +++ EK+ Q EE ++ +EK++ +E K+ ++ + + IR E++
Sbjct: 404 EMMQEQEEKMGEQE-EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462
Query: 381 SRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ K+ EQE K E++ ++Q+QEE+ R QE ++R E+EK+ ++ +E ++RE+
Sbjct: 463 QEQEE-KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR--EQEKK----IREQEEKIREQ 514
Score = 80.5 bits (197), Expect = 5e-15
Identities = 60/204 (29%), Positives = 118/204 (57%), Gaps = 25/204 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAE----------ERKQKELEELERERKR 318
K R+ E+++ QE + R+E+K RE+E + R++ E E+++K E+ E +++
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ 430
Query: 319 EEKLRKREQKQRDRELR-RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIA 377
EEK+R++E+K R++E + R Q++ + Q E ++ +EK+ +E K+ + +Q
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE----Q 486
Query: 378 ELLSRAKAVKLREQEQK----EEKLR-----LQQQEERRRLQEAELRRVEEE-KERALGL 427
E R + K+REQE+K EEK+R +Q+QEE+ QE ++ EE+ +E+ +
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 428 QRKERELRERLLSILLSKKPDDSH 451
+R+E ++RE+ + + ++ H
Sbjct: 547 RRQEEKMREQEVRLRQQEEKMQEH 570
Score = 76.3 bits (186), Expect = 9e-14
Identities = 48/190 (25%), Positives = 119/190 (62%), Gaps = 20/190 (10%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA-----EERQRAEERKQKELEELERERK-----R 318
+K + + +K QE E+ RE++KR+E+EA EE+ R +E K +E EE+ +E++ +
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 319 EEKLRKREQKQRDRE--LRRNQKKL----EKLQAEEQKQLQEKIKLEERKLLLAQRNLQS 372
EEK+ ++E++ +++E +RR ++K+ +K++ +E+K +++ ++E++ + ++ +
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 373 IRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVE----EEKERALGLQ 428
A++ + + ++ +E++ +E++ ++++QEE+ R QE ++ E E++E+ +
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536
Query: 429 RKERELRERL 438
K +E E++
Sbjct: 537 EKMQEQEEKM 546
Score = 75.1 bits (183), Expect = 2e-13
Identities = 56/197 (28%), Positives = 113/197 (57%), Gaps = 28/197 (14%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEA----EERQRAEERKQKELEEL-ERERKRE 319
+ I++++ + ++ +E+ ++EE+ RR++E EE+ R E K E E++ E+E KR+
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQK---------QLQEKIKLEERKLLLAQRNL 370
E+ + REQ++R + + ++ EK++ +E+K + +EK+ +E K+ + +
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 371 QSIRLIAELLSRAKAVKLREQEQK----EEKLRLQQ---QEERRRLQEAELRRVEEE--- 420
Q E R + K+REQE+K EEK+R Q+ QE+ ++ E E + E+E
Sbjct: 428 QE----QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 421 KERALGLQRKERELRER 437
+E+ ++R+E ++RE+
Sbjct: 484 QEQEEKMRRQEEKIREQ 500
Score = 67.8 bits (164), Expect = 3e-11
Identities = 50/173 (28%), Positives = 102/173 (58%), Gaps = 18/173 (10%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELER----ERKREEKLRKR 325
KR+LER KL L Q++ Q + +E Q + Q ++EE E +++EEK+ ++
Sbjct: 236 KRKLERAKL--LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 293
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+K ++RE EK+Q +E+K +++ K+ ++ ++ ++ + R E + K
Sbjct: 294 EEKIQERE--------EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR--QEEMMWEKE 343
Query: 386 VKLREQEQK-EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K+RE E+K E+ ++++QEE+R+ +E ++R E+ +E+ + R+E ++RE+
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQ-EEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Score = 51.6 bits (122), Expect = 2e-06
Identities = 48/161 (29%), Positives = 84/161 (52%), Gaps = 8/161 (4%)
Query: 280 ELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQK 339
ELEQ ++K+A+ R E KE + L E R + E K+++ +L+ +
Sbjct: 164 ELEQALSAVATQKKKAD---RYIEELTKERDALSLELYRNT-ITDEELKEKNAKLQEKLQ 219
Query: 340 KLEKLQAEEQKQLQE-KIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ-EQKEEK 397
+E ++E Q ++E K KLE KLLL Q+ LQ+ ++ + KL+ Q E+ E
Sbjct: 220 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 279
Query: 398 LRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
RL QQ+E + ++ E +++E +E+ + K RE E++
Sbjct: 280 NRLNQQQEEKMWRQEE--KIQEREEKIQEQEEKIREQEEKM 318
Score = 46.2 bits (108), Expect = 1e-04
Identities = 23/90 (25%), Positives = 61/90 (67%), Gaps = 10/90 (11%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKE---------AEERQRAEERKQKELEELERE 315
+A +++++ + ++ +E +++E++ R ++E E+ ++ E+++K E+ E+
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Query: 316 RKREEKLRKREQKQRDRELRRNQKKLEKLQ 345
+++EEK+R++E+K R++E+R Q++ EK+Q
Sbjct: 540 QEQEEKMRRQEEKMREQEVRLRQQE-EKMQ 568
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 83.2 bits (204), Expect = 8e-16
Identities = 57/178 (32%), Positives = 107/178 (60%), Gaps = 13/178 (7%)
Query: 269 KKRQLERQKLQELEQQREEQK--RREKEAEERQRAEERKQKELEELERERKREEKLRKRE 326
+KR+ ER+K ++ E+ ++E+K R+++E E ++R E++ KE EE E+ +K+E+K R R
Sbjct: 67 EKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRT 126
Query: 327 QKQ-RDRELRRNQKKLEKLQAEEQKQLQEKI------KLEERKLLLAQRNLQSIRLIAEL 379
K+ ++RE + +K+ E+ + E +K+ +EK K ERK + + + + E
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 380 LSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
R + K R++E +E K R ++++ER++ +E R+ E +K+R + KER RER
Sbjct: 187 KKRERNRKERKKE-RERKERRERKKERKKKEE---RKKERQKDRQTNWREKERGKRER 240
Score = 80.5 bits (197), Expect = 5e-15
Identities = 57/206 (27%), Positives = 111/206 (53%), Gaps = 21/206 (10%)
Query: 248 AVACNIKVSFDSTKHLS--------DASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
AV N ++ S H+S + I++R+ E + +E +++RE ++++E+ E++
Sbjct: 10 AVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKR 69
Query: 300 RAEERKQKELEELERERKREEKLRKREQKQRDR--------ELRRNQKKLEKLQAEEQKQ 351
+ E K+++ E ++E+K E K +RE+K+R R E + +KK +K + K+
Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129
Query: 352 LQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE 411
+E+ + EERK ++ + + E K K RE++Q EK ++++ER+ ++
Sbjct: 130 GKERERKEERK-REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188
Query: 412 AELRRVEEEKERALGLQRKERELRER 437
E R E +KER +RKER R++
Sbjct: 189 RERNRKERKKER----ERKERRERKK 210
Score = 58.9 bits (141), Expect = 2e-08
Identities = 28/87 (32%), Positives = 62/87 (71%), Gaps = 3/87 (3%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
++++ ER+++ E E++R+E++R+E++ ER R E +K++E +E RERK+E K K+E++
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE-RRERKKERK--KKEER 218
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEK 355
+++R+ R EK + + +++ ++K
Sbjct: 219 KKERQKDRQTNWREKERGKRERKERKK 245
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Query: 575 EQDKCNREPSKGRGRATGDGLADRHKRERSRARRAS---SREDGRPRKERRPHKKHAYKD 631
E++K ++ K RGR + +G K ER R R +E+ +ER+ KK K
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQ 170
Query: 632 DSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRS 691
+ + R+ ++R R++ RER+ RK R +++ ER + R R ++
Sbjct: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKER-KKKEERKKERQKDR-QT 228
Query: 692 TW 693
W
Sbjct: 229 NW 230
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/143 (26%), Positives = 59/143 (41%), Gaps = 11/143 (7%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGD----GLADRHKRERSRARRASSREDG---- 615
E+ RK R E++K RE K R R G G + +RER + RR ++G
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 616 -RPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKH--S 672
R +KE++ + + + R+ R R K+ +ER R+ R RK
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
Query: 673 RHRRRSERSRSRSPSRHRSTWNR 695
+ R E+ R R R+ R
Sbjct: 174 KEEERKEKERKERKKRERNRKER 196
Score = 54.7 bits (130), Expect = 3e-07
Identities = 23/76 (30%), Positives = 52/76 (68%)
Query: 261 KHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREE 320
K + + ++++ ER++ ++ E+ R+E+K+ + E R+R +ERK+KE + ER++ R+
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228
Query: 321 KLRKREQKQRDRELRR 336
R++E+ +R+R+ R+
Sbjct: 229 NWREKERGKRERKERK 244
Score = 53.1 bits (126), Expect = 8e-07
Identities = 27/91 (29%), Positives = 60/91 (65%), Gaps = 10/91 (10%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEER--------QRAEERKQKELEELERERKREE 320
++ + ER+K + + +E++R+EKE +ER +R +ER++KE E ++ERK++E
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Query: 321 KLRKREQKQRDRELRRNQKKLEKLQAEEQKQ 351
+ +++++Q+DR+ +K+ K + +E+K+
Sbjct: 217 E--RKKERQKDRQTNWREKERGKRERKERKK 245
Score = 47.0 bits (110), Expect = 6e-05
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 3/113 (2%)
Query: 573 RSEQDKCNREPSKGRGRATGDGLADRHKRERSRARR--ASSREDGRPRKERRPHKK-HAY 629
R +++ RE K R R + +R ++ER + R +E+ R KER+ KK
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 630 KDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSR 682
+ + + R R + K+ ++ER ++R+ + K R R ER +
Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/111 (21%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 585 KGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHT 644
+G+ + +R +RE+ + R R+ R +KE++ +K ++ RRR
Sbjct: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE------ 103
Query: 645 RSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
+ + + R+++ ++ RG S++ R+ ER R R R R
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Score = 43.9 bits (102), Expect = 5e-04
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 569 RKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERS----RARRASSREDGRPRKERRPH 624
RK E+++ +E K + G+ +R ++ER R R R+ R RKERR
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
Query: 625 KKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSR 661
KK K + ++ T R R R+ER +
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 37.0 bits (84), Expect = 0.062
Identities = 18/94 (19%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 597 DRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR 656
+R R ++ E + R+ER K+ K+ +R + R+ ++R +
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKE--RKRERGKKEKKGERKKEERERKK 99
Query: 657 RERSRERRGSASRKHSRHRRRSERSRSRSPSRHR 690
R R +E + ++ + + + ER R+ + R
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Score = 36.2 bits (82), Expect = 0.11
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 603 RSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR----RE 658
R R R +R++G+ KER +K ++ R+R + R R K R RE
Sbjct: 39 REREREIETRKEGK--KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 659 RSRERRGSASRKHSRHRRRSERSR 682
R + RR +++ +R ++ +
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEK 120
Score = 32.0 bits (71), Expect = 2.0
Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 616 RPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHR 675
R R+ +K K+ R+ + + +R K+R R +E++G +K R R
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER-KKEERER 97
Query: 676 RRSERSRSRSPSRHR 690
++ R + +
Sbjct: 98 KKRRREKENKEGEEK 112
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 82.8 bits (203), Expect = 1e-15
Identities = 60/195 (30%), Positives = 110/195 (56%), Gaps = 28/195 (14%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEER---KQKELEELERERKREEKLRKR 325
K+ + + QK+++ E++ EQ R +E EER R +E+ ++++++E ER R+RE+K+R+
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQ-----------SIR 374
E+ R++E + QK+ E + +E+K+ Q++ E+++ L Q +Q IR
Sbjct: 405 EETMREQE-EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 375 LIAELLSRAKAV----KLREQE----QKEEKLRLQQ-----QEERRRLQEAELRRVEEEK 421
E+ + K + K+REQE ++EEK+R Q+ QEER Q+ LR EE
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523
Query: 422 ERALGLQRKERELRE 436
+ ++E ++RE
Sbjct: 524 REQKKMWQQEEKMRE 538
Score = 82.8 bits (203), Expect = 1e-15
Identities = 48/180 (26%), Positives = 114/180 (63%), Gaps = 15/180 (8%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
D +++++ ER + Q+ Q+EE+ R EK+ +E+++ +++++ E ER R+RE+K+R+
Sbjct: 513 DERLREKE-ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
E+ R++E + Q++ EK++ +E+K +++ K++E++ + ++ ++ + +
Sbjct: 572 EEEMMREQE-EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE-------EKMWEQEE 623
Query: 385 AVKLREQEQK--EEKLRLQQQEERRRLQEAELR----RVEEEKERALGLQRKERELRERL 438
K++EQE+ E++ ++Q+QEE+ QE ++R ++ E++E+ G + K RE E++
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Score = 82.0 bits (201), Expect = 2e-15
Identities = 70/268 (26%), Positives = 137/268 (51%), Gaps = 35/268 (13%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELE 313
K + + K D K R+ ER + +E + + EE+ RE+E ++ +E+++K E+ E
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE----EKMQEQEEKMREQEE 595
Query: 314 RERKREEKLRKREQKQRDRELRR-NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQS 372
+ ++EEK++++E+K ++E + Q++ +K+Q +E+ +++ K++E++ + ++
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ---- 651
Query: 373 IRLIAELLSRAKAVKLREQEQK----EEKLR-----LQQQEERRRLQEAELRRVEE---- 419
E R + K+REQE+K EEK+R +Q QEE+ R QE ++R EE
Sbjct: 652 -----EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
Query: 420 EKERALGLQRK---ERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSS 476
++E+ G + K + E+RE+ I K+ + L P + +
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHT 766
Query: 477 GCVSATTLHPLGGQPPAGAPKESPAHPE 504
G V P GG+ G+P+++P E
Sbjct: 767 GSV-----EPAGGEAGEGSPQDNPTAQE 789
Score = 78.2 bits (191), Expect = 2e-14
Identities = 47/173 (27%), Positives = 105/173 (60%), Gaps = 5/173 (2%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKE---LEELERERKREEKLRK 324
++ L+ + ++ E+ RE++K+ K+ E+ R EER +++ + E E + +R+EK R
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK-RL 285
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
REQ++ RE + ++ +KL+ +E++ +++ K+ E++ + ++ + R L + K
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
++ +EQ+ ++++ R+ +Q+ER R +E +R E+ E+ +Q +ER +RER
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER-IRER 397
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/180 (28%), Positives = 110/180 (61%), Gaps = 13/180 (7%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERK----QKELEELERERKREEKLRK 324
KK + + +K+ E++ EQ+ + +E EE+ R +E++ +KEL E E+E + ++KLR+
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLRE 307
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELL---- 380
+E++ +++E + +++ EK++ +E+K +++ +L E++ + ++ Q +R E +
Sbjct: 308 QEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQE-QKMRDQEERMWEQD 365
Query: 381 --SRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKERELRER 437
R K ++REQE+ E+ Q+EER R +E ++R EE +E+ +Q++E + E+
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Score = 77.0 bits (188), Expect = 5e-14
Identities = 54/173 (31%), Positives = 99/173 (57%), Gaps = 16/173 (9%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
+K E++KL+E E+Q +EQ+ + E EE+ R +E K EE R ++E+++R++EQK
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE--RLWEQEKQMREQEQK 353
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
RD+E R ++ + EE+ + QEK+ +E K+ +R + R K ++
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER----------IREREKKMRE 403
Query: 389 REQEQKEEKLRLQQQEERRRLQEA---ELRRVEEEKERALGLQRKERELRERL 438
E+ +E++ ++Q+QEE QE + +R+ E+KE+ L Q K +E E++
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LWEQEKMQEQEEKI 455
Score = 73.2 bits (178), Expect = 8e-13
Identities = 59/188 (31%), Positives = 110/188 (58%), Gaps = 26/188 (13%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEER----QRAEERKQKELEELERERKREEKLRK 324
KK + E + ++E E++ ++Q+ E EE+ QR E+K+K L E E+ +++EEK+ +
Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LWEQEKMQEQEEKIWE 457
Query: 325 REQKQRDRELRRNQKK----LEKLQAEEQK--QLQEKIKLEERKLLLAQRNL--QSIRLI 376
+E+K RD+E Q+K EK++ +E + + +EK++ +E+K+ + + Q RL
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL- 516
Query: 377 AELLSRAKAVKLREQE---QKEEKLR----LQQQEERRRLQEAELRRVEEEKERALGLQR 429
R K ++REQ+ Q+EEK+R Q+QE++ QE ++R E +ER ++
Sbjct: 517 -----REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 430 KERELRER 437
+E +RE+
Sbjct: 572 EEEMMREQ 579
Score = 73.2 bits (178), Expect = 8e-13
Identities = 56/202 (27%), Positives = 114/202 (56%), Gaps = 21/202 (10%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE---RKQKELEELERERKREEKLRKR 325
K++ E++K+QE E++ EQ+ + ++ EE E+ R++K E+ ++ ++EEK+R +
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
Query: 326 EQKQRDRELR------RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNL---QSIRLI 376
EQK D+E R R ++K E+++ E++K Q++ K+ E K Q Q ++
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMR-EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 377 AELLSRAKAVKLREQEQ--KEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKEREL 434
E R + K+RE+E+ +E++ ++Q+QEE+ R QE ++ EE+ +Q +E ++
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK------MQEQEEKM 611
Query: 435 RERLLSILLSKKPDDSHTHDEL 456
E+ + ++ D +E+
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEM 633
Score = 72.8 bits (177), Expect = 1e-12
Identities = 46/181 (25%), Positives = 101/181 (55%), Gaps = 22/181 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK---R 325
+K + + QK+ + E++ EQ R +E EER R +++ ++ E++ E+K +E+ +K +
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+K R+ E R ++K + + E ++ +EK++ +E K+ + + +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-----------QE 601
Query: 386 VKLREQEQK--EEKLRLQQQEERRRLQEAE------LRRVEEEKERALGLQRKERELRER 437
K++EQE+K E++ ++ +QEE ++QE E +++E++E+ + K RE E+
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Query: 438 L 438
+
Sbjct: 662 M 662
Score = 72.4 bits (176), Expect = 1e-12
Identities = 58/176 (32%), Positives = 100/176 (56%), Gaps = 19/176 (10%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
KR+LER K + Q + EE R +E+K ++ EE + ++EE+LR++E K
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE--KMWRQEERLREQEGKM 271
Query: 330 RDRE--LRRNQKKL---EKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
R++E +RR +K+L EK E++K+L+E+ KL E++ + ++ E +
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ---------EEKMWEQ 322
Query: 385 AVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRER 437
K+REQE+K ++ RL +QE++ R QE ++R EE E+ L+ KE +RE+
Sbjct: 323 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Score = 71.6 bits (174), Expect = 2e-12
Identities = 49/171 (28%), Positives = 102/171 (59%), Gaps = 15/171 (8%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEE--RKQKELEELERERKREEKLRKREQ 327
+ Q ++ + QE + R+E++ RE+E + R++ E+ R++K L E E+E + +EK REQ
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK-ELREQ 302
Query: 328 KQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVK 387
K+ + + Q++ EK+ +E+K +++ K+ ++ L ++ Q R + K
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ---------MREQEQK 353
Query: 388 LREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
+R+QE++ E+ RL+++EER R QE ++ EE+ + ++ +E+++RE
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMRE 403
Score = 67.8 bits (164), Expect = 3e-11
Identities = 54/197 (27%), Positives = 106/197 (53%), Gaps = 18/197 (9%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEA----------EERQRAEERKQK 307
+ K L + + Q E+ + QE + +E+K RE+E E+ ++ E++QK
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
Query: 308 ELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQ 367
++ ER +++E+LR++E++ R++E Q+ EK+Q EE+ + +EK EE + + Q
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQE--EKMQEEERIREREKKMREEEETMREQ 411
Query: 368 R---NLQSIRLIAELLSRAKAVKLREQEQK-EEKLRLQQQEERRRLQEAELRRVEE--EK 421
Q + + + +L EQ++K E+ ++Q+QEE+ QE ++R EE +
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 422 ERALGLQRKERELRERL 438
E+ + Q K RE +++
Sbjct: 472 EKKMWRQEKMREQEDQM 488
Score = 58.2 bits (139), Expect = 3e-08
Identities = 49/167 (29%), Positives = 89/167 (53%), Gaps = 17/167 (10%)
Query: 295 AEERQRA-------EERKQKELEELERERKR------EEKLRKREQKQRDRELRRNQKKL 341
A E QRA ++ + +EEL +ER + E K+++ EL+ +
Sbjct: 140 AGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLA 199
Query: 342 EKLQAEEQKQLQE-KIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRL 400
E ++E Q ++E K KLE K LL Q +Q+ L E+ + + ++ +E++ ++++ ++
Sbjct: 200 ESEKSEIQLNVKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257
Query: 401 QQQEERRRLQEAELRRVEEEKERA-LGLQRKERELRERLLSILLSKK 446
+QEER R QE ++R EE+ R L+ +E+ELRE+ + KK
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Score = 55.8 bits (133), Expect = 1e-07
Identities = 53/192 (27%), Positives = 97/192 (50%), Gaps = 32/192 (16%)
Query: 264 SDASIKKRQLERQKLQELEQQR-----EEQKRREKEAEERQRAEERKQKELEELERERKR 318
+D I++ ER L LE R EE K++ E +E+ R E ++ E++ +E KR
Sbjct: 157 ADRYIEELTKERDALS-LELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR 215
Query: 319 EEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAE 378
KL + + + Q+++ + Q EE ++ ++KI+ +E K+ + L
Sbjct: 216 --KLERAKFLLPQVQTNTLQEEMWR-QEEELREQEKKIRKQEEKMWRQEERL-------- 264
Query: 379 LLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELR----------RVEEEKERALG 426
R + K+REQE+K ++ RL++QE+ R QE ELR +++E++E+
Sbjct: 265 ---REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321
Query: 427 LQRKERELRERL 438
+ K RE E++
Sbjct: 322 QEEKMREQEEKM 333
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/124 (20%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 240 MYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
M++ E+ + ++ ++ + + + K + E + ++ E+ RE++++ + + E+ +
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677
Query: 300 RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE 359
EE+ Q + E++ R++EEK+R +E+K +E + ++ + EE ++ +E+I+ +
Sbjct: 678 EQEEKMQGQEEKM---REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Query: 360 ERKL 363
+ K+
Sbjct: 735 KEKM 738
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 82.4 bits (202), Expect = 1e-15
Identities = 102/434 (23%), Positives = 186/434 (42%), Gaps = 66/434 (15%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
I++++ +R++L+E +Q+RE + RR++E E+R+R +E K++ LEELER RK EE+ R+ E+
Sbjct: 399 IEQQKEQRRRLEE-QQRREREARRQQEREQRRREQEEKRR-LEELERRRKEEEERRRAEE 456
Query: 328 KQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVK 387
++R + R Q+ + + EEQ+ L+ + +++LL Q L R E+ +A +
Sbjct: 457 EKR--RVEREQEYIRRQLEEEQRHLE----VLQQQLLQEQAMLLECRW-REMEEHRQAER 509
Query: 388 LREQEQKEEKLRLQQQEERRR-----LQEAELRRVEEEKERALGLQRKE--------REL 434
L+ Q Q+E+ L Q + RR Q+ + E K + K RE+
Sbjct: 510 LQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREV 569
Query: 435 RERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPA- 493
+R +K + S + L PV ++ S+G ++ ++HP +P
Sbjct: 570 EDRF------RKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNG--NSESVHPALQRPAEP 621
Query: 494 ------------GAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKR 541
S +H +D +PK + + + PC +S D E
Sbjct: 622 QVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAP 681
Query: 542 CPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKR 601
P D+++ P +P + SR S +D P +G G +
Sbjct: 682 DPTQKAWSRSDSDEVPPRVPV--RTTSRSPVLSRRD----SPLQGSG------------Q 723
Query: 602 ERSRARRASSREDGRP-----RKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR 656
+ S+A + +S P R E+ + + + P +S S +R R
Sbjct: 724 QNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFR 783
Query: 657 RERSRERRGSASRK 670
S + GS S++
Sbjct: 784 VRSSSKSEGSPSQR 797
Score = 69.3 bits (168), Expect = 1e-11
Identities = 54/204 (26%), Positives = 109/204 (53%), Gaps = 15/204 (7%)
Query: 253 IKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEEL 312
+ V +ST +++ ER + +Q +EQ+ RE+E +RQ ER+++ ++
Sbjct: 344 VNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQK 403
Query: 313 ERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI---KLEERKLLLAQRN 369
E+ R+ E EQ++R+RE RR Q++ ++ + +E+K+ E++ + EE + A+
Sbjct: 404 EQRRRLE------EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEE 457
Query: 370 LQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQR 429
+ + E + R +L E+++ E L+ Q +E+ L E R +EE ++ A LQR
Sbjct: 458 KRRVEREQEYIRR----QLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQ-AERLQR 512
Query: 430 KERELRERLLSILLS-KKPDDSHT 452
+ ++ + LLS+ ++P H+
Sbjct: 513 QLQQEQAYLLSLQHDHRRPHPQHS 536
Score = 67.4 bits (163), Expect = 4e-11
Identities = 114/467 (24%), Positives = 189/467 (40%), Gaps = 104/467 (22%)
Query: 268 IKKRQLERQKLQELEQQ--REEQKRREK-EAEERQRAEERKQKELEELERERKR------ 318
I+ + ERQ +L+ R +KR EK E E E +++E+ E E E
Sbjct: 289 IRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPG 348
Query: 319 EEKLRK------REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQS 372
E LR+ +E K+R LRR Q+ L++ Q EQ++ + ++ L ER+ + Q+ Q
Sbjct: 349 ESTLRRDFLRLQQENKERSEALRR-QQLLQEQQLREQEEYKRQL-LAERQKRIEQQKEQR 406
Query: 373 IRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKER 432
RL + +A + +E+EQ R ++QEE+RRL+E E RR EEE ER + K R
Sbjct: 407 RRLEEQQRREREARRQQEREQ-----RRREQEEKRRLEELERRRKEEE-ERRRAEEEKRR 460
Query: 433 ELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPP 492
RE+ + ++ ++ H L V LLQ +L+
Sbjct: 461 VEREQ---EYIRRQLEEEQRH--LEVLQQQLLQEQAMLLEC------------------- 496
Query: 493 AGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPD 552
+E H +A+ + + E+A +Q R P P
Sbjct: 497 --RWREMEEHRQAERLQRQLQ---QEQAYLLSLQHDHR------RPH-----------PQ 534
Query: 553 NNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSR 612
++QQP P +Q S+ + + K + EP+ R R + DR ++ + A S+
Sbjct: 535 HSQQP---PPPQQERSKPSFHAPEPKAHYEPA-DRARE----VEDRFRKTNHSSPEAQSK 586
Query: 613 EDGRPRKERRPHKKHAYKDDS----------PRRRSTSPDHTRS--------RRSHS--- 651
+ GR + P + ++ + + P H S RSHS
Sbjct: 587 QTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSD 646
Query: 652 ---KDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
K H RS++ S +S S+S +P + W+R
Sbjct: 647 PSPKFAHHHLRSQD---PCPPSRSEVLSQSSDSKSEAPDPTQKAWSR 690
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 81.3 bits (199), Expect = 3e-15
Identities = 58/196 (29%), Positives = 115/196 (58%), Gaps = 27/196 (13%)
Query: 268 IKKRQLERQKLQELEQQR-EEQKRREKEAEERQRA----EERKQKELEELERERKR---- 318
++++ E++K++E E++R EE+K RE+E + Q A +E K +E EE RE+++
Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 441
Query: 319 -------EEKLRKREQKQRDRELRRNQKKL----EKLQAEEQKQLQEKIKLEERKLLLAQ 367
+EK+R+ E++Q E+ R ++K+ E + +E+ QEKI+ +E K+ +
Sbjct: 442 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE 501
Query: 368 RNL----QSIRLIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEK 421
+ + IR E + R + K+REQE+K E++ ++++QEE + QE ++ EE+
Sbjct: 502 EKMHDQEEKIREQEEKMWRQEE-KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 422 ERALGLQRKERELRER 437
+ ++R+E ++RE+
Sbjct: 561 QEQEKMRRQEEKIREQ 576
Score = 79.3 bits (194), Expect = 1e-14
Identities = 49/171 (28%), Positives = 106/171 (61%), Gaps = 16/171 (9%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
+K + +K++E E++ Q+ + +E EE+ R +E K +E EE+ +E+ EEK+ ++E+K
Sbjct: 502 EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ--EEKMGEQEEK 559
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
+++E R Q++ + Q E+ ++ +EKI+ +E K+ + + R + +
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI-----------REQEEMM 608
Query: 389 REQEQK--EEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRE 436
+EQE+K E++ ++ +QEE+ + QE ++RR EE+ E+ + L+++E +++E
Sbjct: 609 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 77.4 bits (189), Expect = 4e-14
Identities = 59/208 (28%), Positives = 120/208 (57%), Gaps = 17/208 (8%)
Query: 243 GEDGKAVACNIKVSFDSTK---HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
G++ ++V+ ++ + + L+ +K + +K+QE E++ +EQ+ + +E EE+
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 300 RAEERKQKELEELERERKREEKLRKREQK--QRDRELRRNQ----KKLEKL-QAEEQKQL 352
R +E K + EE+ E+ EEK+R++E+ +++ ++RR + +K EK+ + EE+
Sbjct: 331 REQEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
Query: 353 QEKIKLEERKLLLAQR-NLQSIRLIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRL 409
QEKI+ +E K ++ Q R E + K+REQE+K E++ ++ +QEE ++
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE--KI 446
Query: 410 QEAELRRVEEEKERALGLQRKERELRER 437
E E R EE+++ + R+E ++RE+
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQ 474
Score = 77.4 bits (189), Expect = 4e-14
Identities = 68/229 (29%), Positives = 124/229 (54%), Gaps = 45/229 (19%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKEL-------EELERERKREEK 321
KK + +K+ E E+ REE+KR+E+E RQ + R+Q+E+ E E+ RK+EEK
Sbjct: 437 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK 496
Query: 322 LRKREQKQRDRE--LRRNQKKL-----------EKLQAEEQK---------QLQEKIKLE 359
+ ++E+K D+E +R ++K+ EK++ +E+K + +EK+ +
Sbjct: 497 VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
Query: 360 ERKLL---LAQRNLQSIRLIAELLSRAKAVKLREQEQK----EEKLR-----LQQQEERR 407
E K+ +R + IR E + R + K+REQE+K EEK+R +Q+QEE+
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKI-REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
Query: 408 RLQEAELRRVEEE-KERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
QE ++ EE+ +E+ ++R+E ++ E+ + L ++ + H E
Sbjct: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ--EVRLRQQEEKMQEHQE 662
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/186 (27%), Positives = 98/186 (52%), Gaps = 28/186 (15%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKR---------E 319
+KRQ + K+ E++ EQ+ + +E E++ +E K E E++ E KR E
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 320 EKLRKREQKQRDRELRRNQKKLEK------LQAEEQKQLQEKIKLEERKLLLAQRNLQSI 373
EK+R++E+ R +E Q+K+ K Q E+ +EKI+ +E K+ + +
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI--- 525
Query: 374 RLIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKE 431
R + K+REQE+K E++ +Q+QEE+ QE +++ E+ + + ++ +E
Sbjct: 526 --------REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE 577
Query: 432 RELRER 437
++RE+
Sbjct: 578 EKIREQ 583
Score = 74.3 bits (181), Expect = 3e-13
Identities = 55/202 (27%), Positives = 117/202 (57%), Gaps = 29/202 (14%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEA-----EERQRAEE---RKQKELEELERER 316
+ I++++ + ++ +E+ ++EE+ RR++E E+ +R EE K++++ ELE +
Sbjct: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 386
Query: 317 KREEKLRKREQKQRDRELRRNQKKLEKLQA------EEQKQLQEKIKLEERKLLLAQRNL 370
+EK+R++E+K+++ E R Q+K ++ +A E+ ++ +EKI+ +E+K+ + +
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 446
Query: 371 QSIRLIAELLSR-------AKAVKLREQE----QKE---EKLRLQQQEERRRLQEAELRR 416
I E R + K+REQE QKE E+ ++++QEE+ QE ++
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 417 VEEE-KERALGLQRKERELRER 437
EE+ +E+ + R+E ++RE+
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQ 528
Score = 72.4 bits (176), Expect = 1e-12
Identities = 39/157 (24%), Positives = 97/157 (61%), Gaps = 4/157 (2%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
+K + +K++E E++ EQ+ + +E EE + +E K E EE +E +EK+R++E+K
Sbjct: 516 EKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE---QEKMRRQEEK 572
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
R++E + ++K EK++ +E+K +++ K+ E++ ++ ++ + ++ + + ++
Sbjct: 573 IREQEEKIREQK-EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Query: 389 REQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERAL 425
+E++ + ++ ++ +QE R R QE +++ +E E A+
Sbjct: 632 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 67.0 bits (162), Expect = 6e-11
Identities = 51/198 (25%), Positives = 107/198 (54%), Gaps = 40/198 (20%)
Query: 270 KRQLERQKLQELEQQ------------------------------REEQKRREKEAEERQ 299
KR+LER KL +QQ R Q++ EK + +
Sbjct: 248 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 307
Query: 300 RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE 359
+ +E ++K E+ E+ R++EEK+R++E+K R +E +K+ EK++ +E+ +++ K+
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMR 366
Query: 360 ERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEE 419
+ ++ ++ + IR + E + + K+REQE+K ++ +++E+R+ QEA++ R EE
Sbjct: 367 RLEEMMWEKE-EKIRELEEKMHEQE--KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 420 EKERALGLQRKERELRER 437
+ ++ +E ++RE+
Sbjct: 424 K------IREQEEKIREQ 435
Score = 60.5 bits (145), Expect = 5e-09
Identities = 43/163 (26%), Positives = 87/163 (53%), Gaps = 31/163 (19%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELE 313
K+ K + + Q E+ QE + Q +E+ RR++E + E+++K E+ E
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE-----KIREQEEKIREQKE 585
Query: 314 RERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI 373
+ R++EEK+ ++E+K R++E Q++ EK+ +E+K +++ K++E++
Sbjct: 586 KIREQEEKIWEQEEKIREQE-EMMQEQEEKMWEQEEKMCEQEEKMQEQE----------- 633
Query: 374 RLIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAEL 414
K+R QE+K E+++RL+QQEE+ + + L
Sbjct: 634 ------------EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/188 (26%), Positives = 99/188 (52%), Gaps = 34/188 (18%)
Query: 263 LSDASIKKRQLERQ-KLQELEQQREEQKRREKEAEER-QRA-----EERKQKELEELERE 315
++D +K++ + Q KLQ +E ++ E + KE + + +RA +++ Q E + L +E
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
Query: 316 RKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQK--QLQEKIKLEERKLLLAQRNLQSI 373
+ + + ++ + R NQ++ EK+ +E+K + +EKI+ +E K+
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI---------- 323
Query: 374 RLIAELLSRAKAVKLREQEQK---EEKLRLQQQEERRRLQEAELRRVEEEKERALG--LQ 428
R + K+REQE+K +E++ +++E+ RR + E+ +EEK R L +
Sbjct: 324 --------REQEEKIREQEEKMRRQEEMMWEKEEKMRR--QEEMMWEKEEKMRRLEEMMW 373
Query: 429 RKERELRE 436
KE ++RE
Sbjct: 374 EKEEKIRE 381
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/201 (28%), Positives = 99/201 (49%), Gaps = 29/201 (14%)
Query: 280 ELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQK 339
ELEQ ++K+A+ R E KE + L E R + E K+++ +L+ +
Sbjct: 176 ELEQALSAVATQKKKAD---RYIEELTKERDALSLELYRNT-ITDEELKEKNAKLQEKLQ 231
Query: 340 KLEKLQAEEQKQLQE-KIKLEERKLLLAQRNLQ-------------SIRLIAEL------ 379
+E ++E Q ++E K KLE KLLL Q+ LQ S +L A++
Sbjct: 232 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 380 --LSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELR 435
L++ + K+ QE+K E + ++Q+QEE+ R QE ++R +EEK R E+E +
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE-QEEKMRRQEEMMWEKEEK 350
Query: 436 ERLLSILLSKKPDDSHTHDEL 456
R ++ +K + +E+
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEM 371
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/202 (22%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 263 LSDASIKKRQLERQKLQELEQQR--------------EEQKRREKEAEERQRAEERKQKE 308
LS + +K++ +R ++EL ++R EE K + + +E+ + E ++ E
Sbjct: 181 LSAVATQKKKADRY-IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
Query: 309 LE----ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLL 364
++ EL+R+ +R + L ++Q Q + + K+L+ + A+ Q Q++E E L
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQLQAEAD--HLGKELQSVSAKLQAQVEEN---ELWNRL 294
Query: 365 LAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERA 424
Q+ + R ++ + ++ +E++ +E++ ++++QEE+ R QE + EE+ R
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 425 LGLQRKERELRERLLSILLSKK 446
+ ++ E RL ++ K+
Sbjct: 355 EEMMWEKEEKMRRLEEMMWEKE 376
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 81.3 bits (199), Expect = 3e-15
Identities = 89/285 (31%), Positives = 139/285 (48%), Gaps = 32/285 (11%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
+ +RQ ER L+E E++ EQ+ R E EER +E + E EE R R++EE+LR++E+
Sbjct: 193 LNRRQEER--LREQEERLHEQEERLHEQEERLCEQEERLCEQEE--RLREQEERLREQEE 248
Query: 328 KQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAE---LLSRAK 384
+ ++E R +++ + EE+ QEK+ +ER L ++ L+ R E LL R +
Sbjct: 249 RLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERER 308
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEA--ELRRVEE-EKERALGLQRKERELRERLLSI 441
L E E+ E+ RL+QQ+ER QE EL R+ E E+ R L R+ + E
Sbjct: 309 L--LDEVEELLEQERLRQQDERLWQQETLRELERLRELERLRELERLRELERMLELGWEA 366
Query: 442 LLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSS-------GCVSATTLHPLGGQP-PA 493
L ++ + +EL + LQ + + S G SA P+ G P P
Sbjct: 367 LYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSESAAAARPVPGAPVPQ 426
Query: 494 GA---------PKESPA-HPEADGAPKSVNGSVAEEAPCKEVQSS 528
GA P+E P EA G ++ G AEEA C +++
Sbjct: 427 GAWMCGQAGWTPQEHPGLSGEAVGTGEAAGG--AEEAACHSFRAA 469
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 89/178 (50%), Gaps = 49/178 (27%)
Query: 280 ELEQQREEQKRREKEAEE--RQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRN 337
++EQ ++E KE E RQ E + ++ L R++EE+LR++E++ ++E R +
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL-LNRRQEERLREQEERLHEQEERLH 216
Query: 338 QKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEK 397
+++ E+L +E++ +++ +L E++ +LREQE+
Sbjct: 217 EQE-ERLCEQEERLCEQEERLREQE-----------------------ERLREQEE---- 248
Query: 398 LRLQQQEER-----RRLQEAELRRVEEEK-----------ERALGLQRKERELRERLL 439
RL +QEER RL E E R E+EK E+ L +R++ E +ERLL
Sbjct: 249 -RLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEE-QERLL 304
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 80.1 bits (196), Expect = 6e-15
Identities = 59/183 (32%), Positives = 111/183 (60%), Gaps = 16/183 (8%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKEL--------EELERERKREE 320
KK + +K+ E E+ REE+KR+E+E RQ + +Q+E+ E+ E+ RK+EE
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 321 KLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNL-QSIRLIAEL 379
K+ ++E+K R++E + +++ + + EE+ + QE++ EE K+ ++ + R E
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 380 LSRAKAVKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKEREL 434
+ K+REQE+K EEK+R +QEE+R+ QE ++ + EE+ +E+ +Q +E ++
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIR--EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 435 RER 437
RE+
Sbjct: 629 REQ 631
Score = 79.3 bits (194), Expect = 1e-14
Identities = 54/223 (24%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 243 GEDGKAVACNIKVSFDSTK---HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
G++ ++V+ ++ + + L+ +K + +K+QE E++ +EQ+ + +E EE+
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 300 RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE 359
R +E K + EE+ E+ EEK+R++E+ ++E + +++ + EE+ + QE++ E
Sbjct: 331 REQEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 360 ERKLL--LAQRNLQSIRLIAELLSRAKAVKLREQEQK-EEKLRLQQQEERRRLQEAELRR 416
+ + + L ++ + ++ + R + K+REQE++ E++ ++ +QEE+ R QE ++R
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 417 VEEE---KERALGLQRKERELRERLLSILLSKKPDDSHTHDEL 456
E++ +E + Q K RE +R + ++ + H +E+
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Score = 78.2 bits (191), Expect = 2e-14
Identities = 61/194 (31%), Positives = 114/194 (58%), Gaps = 26/194 (13%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA-----EERQRAEERKQKELEE----LERERKRE 319
+K + + +K QE E+ RE++KR+E+EA EE+ R +E K +E E+ E + +
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
Query: 320 EKLRKREQKQRDRELRRNQKKLEK-----LQAEEQKQLQEKIKLEERKLLLAQRNL---- 370
EK+R+ E++Q E+ R ++K+ + Q E+ + +EKI+ +E K+ + +
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 371 QSIRLIAELLSRAKAVKLREQEQ---KEEKLRLQQ---QEERRRLQEAELRRVEEE-KER 423
+ IR E + R + K+REQE+ +EEK+ Q+ +EE+R+ QE ++ R EE+ +E+
Sbjct: 524 EKIREQEEKMWRQEE-KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 424 ALGLQRKERELRER 437
+ R+E ++RE+
Sbjct: 583 EEKVWRQEEKIREQ 596
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/173 (29%), Positives = 103/173 (59%), Gaps = 14/173 (8%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
++ ++ RQK + EQ+ + +K+ EK + ++ E+++K E+ E+ ++EEK+R++E+
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546
Query: 329 QRDRELRRNQKKL---EKLQAEEQK--QLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
R+ E Q+K+ EK Q +E K + +EKI+ +E K+ + ++ E +
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE----QEEKRQE 602
Query: 384 KAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEE---EKERALGLQRKE 431
+ K+ +QE+K E++ ++Q+QEE+ R QE ++R EE E+E +G Q ++
Sbjct: 603 QEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 75.5 bits (184), Expect = 2e-13
Identities = 61/179 (34%), Positives = 113/179 (63%), Gaps = 16/179 (8%)
Query: 271 RQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEEL-ERERKREEKLRK-REQK 328
RQ E+ + QE + R+E+K RE+E E+RQ EE+ K+ E++ E+E K +E+ K REQ+
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQE-EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 329 QRDRELRR-NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVK 387
++ RE Q++ EK+ +E+K +++ K++E++ + R + IR E R + K
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM-WRQEEKIR-EQEKKIREQEEK 690
Query: 388 LREQE----QKEEKL-----RLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRE 436
+REQE ++EEK+ ++ +QEE+ + QE ++RR EE+ E+ + L+++E +++E
Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/210 (24%), Positives = 122/210 (58%), Gaps = 17/210 (8%)
Query: 234 LRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREK 293
L KL+ + +A A ++ S A +++ +L + Q+ E++ Q+ + +
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 310
Query: 294 EAEERQRAEERKQKELEELERERKREEKLRKREQK--QRDRELRRNQ----KKLEKLQAE 347
E EE+ + +E K +E E E+ R++EEK+R++E+ +++ ++RR + +K EK++ +
Sbjct: 311 EWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
Query: 348 EQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERR 407
E+ +++ K+ ++ ++ ++ + IR + E + + K+REQE+K ++ +++E+R
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKMHEQE--KIREQEEKRQEEEKIREQEKR 425
Query: 408 RLQEAELRRVEEEKERALGLQRKERELRER 437
+ QEA++ R EE+ ++ +E ++RE+
Sbjct: 426 QEQEAKMWRQEEK------IREQEEKIREQ 449
Score = 74.3 bits (181), Expect = 3e-13
Identities = 53/175 (30%), Positives = 111/175 (63%), Gaps = 17/175 (9%)
Query: 269 KKRQLERQKLQELEQQ-REEQKRREKE-AEERQRAEERKQKELEELERERKREEKLRKRE 326
+K + +K++E E+ REE+K E+E E ++ +E++ K + E+ R++EEK+ ++E
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 327 QKQRDRELRRNQKKLEKLQAEEQK--QLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
+K R++E +R Q++ EK+ +E+K + +EKI+ +E K+ + ++ E +++ +
Sbjct: 591 EKIREQEEKR-QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE----QEEMTQEQ 645
Query: 385 AVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K+ EQE+K E++ ++Q+QEE QE ++R E+EK+ ++ +E ++RE+
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR--EQEKK----IREQEEKIREQ 694
Score = 72.8 bits (177), Expect = 1e-12
Identities = 53/187 (28%), Positives = 107/187 (57%), Gaps = 22/187 (11%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA--EERQRAEERKQKELEELERERKREEKLRKRE 326
K+ ++ RQ +E+ ++EE+ RR++E E+ ++ E ++K + E E+ R++EEK R+ E
Sbjct: 361 KEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKIRELEEK-MHEQEKIREQEEK-RQEE 416
Query: 327 QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAV 386
+K R++E R+ Q+ Q E+ ++ +EKI+ +E+K+ + + I E R +
Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Query: 387 KLREQEQK--------EEKLRLQQQEERRRLQEAELRRVEEE--------KERALGLQRK 430
++ QE+K +K ++ +QEE+ R QE ++ R EE+ +E+ + R+
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Query: 431 ERELRER 437
E ++RE+
Sbjct: 537 EEKIREQ 543
Score = 70.9 bits (172), Expect = 4e-12
Identities = 46/179 (25%), Positives = 107/179 (59%), Gaps = 15/179 (8%)
Query: 274 ERQKLQELEQQREEQKRREKE-----AEERQRAEERK-----QKELEELERERKREEKLR 323
E +K+ E E+ EE+KR+E+E EE+ R +E K +K E+ E+ +++EEK+
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
K+E+K R++E + Q++ EK++ +E+K +++ +E++ + ++ + ++ +
Sbjct: 609 KQEEKIREQE-EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 384 KAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVE----EEKERALGLQRKERELRERL 438
+ + +E++ +E++ ++++QEE+ R QE ++ E E++E+ + K +E E++
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726
Score = 68.2 bits (165), Expect = 2e-11
Identities = 52/186 (27%), Positives = 104/186 (55%), Gaps = 14/186 (7%)
Query: 262 HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKR--- 318
H + I+K++ +K+ E++ EQ+ + +E EE+ +E K +E EE+ RE ++
Sbjct: 499 HEQEEKIRKQE---EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 319 EEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNL----QSIR 374
+EK+ + E++Q + Q++ + Q E+ + +EKI+ +E K + + + IR
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 375 LIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKE 431
E + + K+REQE+K E++ Q+QEE+ QE ++ EE+ +E+ + R+E
Sbjct: 616 EQEEKIQEQEE-KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 432 RELRER 437
++RE+
Sbjct: 675 EKIREQ 680
Score = 66.6 bits (161), Expect = 7e-11
Identities = 48/180 (26%), Positives = 102/180 (56%), Gaps = 24/180 (13%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA----EERQRAEER----KQKELEELERERKREE 320
K+ ++ RQ +E+ ++EE+ RR++E EE+ R +E K++++ ELE + +E
Sbjct: 347 KEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 321 KLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELL 380
K+R++E+K+++ E R Q+K ++ +A+ +Q +EKI+ +E K+ ++ +
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIREQEEKIREQEKKMWR-------- 455
Query: 381 SRAKAVKLREQEQ--KEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
+ K+ EQE+ +EEK + Q++ R+ + E + +KE+ + K R+ E++
Sbjct: 456 ---QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Score = 58.2 bits (139), Expect = 3e-08
Identities = 40/171 (23%), Positives = 98/171 (57%), Gaps = 7/171 (4%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELER----ERKREEKLRKR 325
KR+LER KL L Q++ Q + +E Q + Q ++EE E +++EEK+ ++
Sbjct: 248 KRKLERAKL--LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+K ++ E + Q++ EK++ +E+K +++ K+ ++ ++ ++ + R + + +
Sbjct: 306 EEKIQEWE-EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 386 VKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
++ +E+ E++ ++++QEE +E ++R +EE+ ++ +E + +E
Sbjct: 365 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 415
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/200 (29%), Positives = 107/200 (53%), Gaps = 29/200 (14%)
Query: 263 LSDASIKKRQLERQ-KLQELEQQREEQKRREKEAEER-QRA-----EERKQKELEELERE 315
++D +K++ + Q KLQ +E ++ E + KE + + +RA +++ Q E + L +E
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
Query: 316 RKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQK--QLQEKIKLEERKLLLAQRNLQSI 373
+ + + ++ + R NQ++ EK+ +E+K + +EKI+ +E K+ + + I
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI---REQEEKI 330
Query: 374 RLIAELLSR------AKAVKLREQE----QKEEKLRLQQQ-----EERRRLQEAELRRVE 418
R E + R K K+R QE +KEEK+R Q++ EE+ R QE E+ +
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE-EMMWEK 389
Query: 419 EEKERALGLQRKERE-LRER 437
EEK R L + E+E +RE+
Sbjct: 390 EEKIRELEEKMHEQEKIREQ 409
Score = 50.1 bits (118), Expect = 7e-06
Identities = 32/119 (26%), Positives = 69/119 (57%), Gaps = 11/119 (9%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKE-----AEERQRAEERKQKE 308
K+ K + + Q E+ QE + +E+K +E+E EE+ R +E+K +E
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Query: 309 LEELERE-----RKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
EE RE +++EEK+ ++E+K ++E + Q++ EK++ +E+K +++++L +++
Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/77 (32%), Positives = 48/77 (62%), Gaps = 10/77 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
KK + + +K++E E+ +EQ+ + E EE+ +E K +E +EEK+R++E+K
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE---------QEEKMRRQEEK 732
Query: 329 QRDRELRRNQKKLEKLQ 345
++E+R Q++ EK+Q
Sbjct: 733 MWEQEVRLRQQE-EKMQ 748
Score = 29.6 bits (65), Expect = 9.8
Identities = 16/67 (23%), Positives = 35/67 (52%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELE 313
K+ K + + Q E+ QE + +E+K +E+E + R++ E+ ++E+ +
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Query: 314 RERKREE 320
+E K +E
Sbjct: 743 QEEKMQE 749
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 79.3 bits (194), Expect = 1e-14
Identities = 52/185 (28%), Positives = 101/185 (54%), Gaps = 6/185 (3%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK 317
D+ K L + KK + ERQ++++ ++RE ++ RE+E ER+R ER+++ +E ERER+
Sbjct: 286 DTHKKLEEEKGKKEK-ERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 318 REEKLRKREQKQRDRELRRNQ-----KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQS 372
RE + K+RDR+ R + ++ + +++ + +EK + ER+ + +
Sbjct: 345 RERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERE 404
Query: 373 IRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKER 432
E + + RE+E++++K R ++++E + +L R EKE A + K
Sbjct: 405 REREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW 464
Query: 433 ELRER 437
E+RER
Sbjct: 465 EIRER 469
Score = 79.0 bits (193), Expect = 1e-14
Identities = 77/318 (24%), Positives = 149/318 (46%), Gaps = 62/318 (19%)
Query: 256 SFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAE-ERQRAEERKQKELEELER 314
S D K S + K R ER++ +E E++RE ++ RE+E E ER+R ER++++ ++ +R
Sbjct: 374 SSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433
Query: 315 E---------RKREEKLRKREQKQRDR----ELRRNQKKLE-KLQAEEQKQLQEKIKLEE 360
E RK E KLR++E ++R E+R +K E + +AE +++ + ++ E
Sbjct: 434 EEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEA 493
Query: 361 RKLLLAQRNLQSIR----------LIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQ 410
++L + R L L R K ++ E+++K EK L++ +R +
Sbjct: 494 KRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAE 553
Query: 411 -----EAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQ 465
+AEL+R+E+E ER R++ ++++ +P+ +E +
Sbjct: 554 GHPDPDAELQRMEQEAER-----RRQPQIKQ---------EPESEEEEEEKQEKEEKREE 599
Query: 466 PVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEV 525
P+ + + C+ TL P+ P + + A P G +E+PC
Sbjct: 600 PMEEEEEPEQKPCLK-PTLRPISSAPSVSSASGN-ATPNTPG----------DESPCG-- 645
Query: 526 QSSCRVVPEDGSPEKRCP 543
++P + SP+++ P
Sbjct: 646 ----IIIPHENSPDQQQP 659
Score = 74.7 bits (182), Expect = 3e-13
Identities = 51/184 (27%), Positives = 107/184 (58%), Gaps = 5/184 (2%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEER-KQKELEELERER 316
+ + L I K + +KL+E E+ ++E++R+E E E R+R ER +++E E ERER
Sbjct: 271 EDKRDLISREISKFRDTHKKLEE-EKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 317 KREEKLRKREQKQRDRELRRNQ---KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI 373
+RE + K ++++R+RE R++ K+ ++ + E+ + +++ + +R ++ +S
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 374 RLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERE 433
E + + RE+E++ E+ R +++E R ++ + R EE++E A ++ ER+
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Query: 434 LRER 437
LRE+
Sbjct: 450 LREK 453
Score = 55.5 bits (132), Expect = 2e-07
Identities = 46/131 (35%), Positives = 61/131 (46%), Gaps = 10/131 (7%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRAR-RASSREDGRPRKERR 622
E+ ++ R E +K RE + R R +R +RER R R R +E R R+ R
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERER-----ERREREREREREREREKEKERERERER 347
Query: 623 PHKKHAYKD-DSPRRRSTSPDHTRSRRS-HSKDRHR-RERSRERRGSASRKHSRHRRRSE 679
+ K+ D R R D R R S +KDR R RE+SR+R R+ R R R E
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER-E 406
Query: 680 RSRSRSPSRHR 690
R R R R R
Sbjct: 407 RERERERERER 417
Score = 54.3 bits (129), Expect = 4e-07
Identities = 50/177 (28%), Positives = 76/177 (42%), Gaps = 9/177 (5%)
Query: 520 APCKEVQSSCRVVPEDGSPE--KRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQD 577
AP +E S R ++ + +R P V IP + I A E ++D S +
Sbjct: 224 APSQESDSHPRKKKKEKKEDIFRRFP--VAPLIPYPLITKEDINAIEMEEDKRDLISREI 281
Query: 578 KCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRR 637
R+ K G +R + E+ R R RE R R+ER ++ + + + R
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 638 STSPDHTRSR-RSHSKDRHR---RERSRERRGSASRKHSRHRRRSERSRSRSPSRHR 690
+ R R R+ +DR R R+R R+R S+ R R R R E+SR R R R
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR-EKSRDRERERER 397
Score = 52.8 bits (125), Expect = 1e-06
Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 8/128 (6%)
Query: 570 KDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPR-KERRPHKKHA 628
+DT + ++ + K R + +RER R RR RE R R +E+ ++
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 629 YKDDSPRRRSTSPDHTRSR-RSHSKDRHR-----RERSRERRGSASRKHSRHRRRSERSR 682
+ D R R+ D R R R +DR R ++RSR R S R+ R R R ER R
Sbjct: 345 RERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERER-ERER 403
Query: 683 SRSPSRHR 690
R R R
Sbjct: 404 ERERERER 411
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 1/127 (0%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
E+ ++ E+++ RE + R R +RER R R + D +ER
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRS 683
+ D + RS S + +R R + RER RER R+ R R R ER R
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERER-ERERE 426
Query: 684 RSPSRHR 690
+ R R
Sbjct: 427 KDKKRDR 433
Score = 40.4 bits (93), Expect = 0.006
Identities = 30/128 (23%), Positives = 47/128 (36%), Gaps = 1/128 (0%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRAR-RASSREDGRPRKERR 622
+++ R R + +R + R R +RER R R R RE R R+ R
Sbjct: 360 DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERER 419
Query: 623 PHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSR 682
++ KD R D R+ K R + +ER + + + R E+
Sbjct: 420 EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEA 479
Query: 683 SRSPSRHR 690
R R R
Sbjct: 480 EREEERRR 487
Score = 38.5 bits (88), Expect = 0.021
Identities = 24/119 (20%), Positives = 49/119 (41%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
++N R +R + RE + R R +RER R R + +++R
Sbjct: 376 DRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREE 435
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSR 682
++ AY+ R+ + R + + R+++RE A R+ R R ++ ++
Sbjct: 436 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAK 494
Score = 38.1 bits (87), Expect = 0.028
Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLA-DRHKRERS-RARRASSRE-----DGR 616
E+ R+ R + + RE K R R + A +R K ER R + A+ +E + R
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Query: 617 PRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRR 676
RK+ R ++K A +++ RRR + + R + R+ + RGSA +K R R
Sbjct: 468 ERKKTREYEKEAEREEE-RRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526
Query: 677 RSERSRSRSPSRHR 690
+ + R R +
Sbjct: 527 KEMEADERDRKREK 540
Score = 35.4 bits (80), Expect = 0.18
Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 13/131 (9%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK-RERSRAR---RASSREDGRPR- 618
E++ R T+ +RE + R R +DR+K R RSR + R RE R R
Sbjct: 346 ERDRDRDRTKERDRDRDRERDRDRDRERS---SDRNKDRSRSREKSRDRERERERERERE 402
Query: 619 --KERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRR---ERSRERRGSASRKHSR 673
+ER ++ + + R R D R R +D + R ER + +A ++ +
Sbjct: 403 REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK 462
Query: 674 HRRRSERSRSR 684
+ ER ++R
Sbjct: 463 NWEIRERKKTR 473
Score = 34.7 bits (78), Expect = 0.31
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK-RERSRAR---RASSREDGRPRK 619
E+ ++ R + +R+ +K R R D DR + RERS R R+ SRE R R+
Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDR-DRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
Query: 620 ERRPHKKHAYKD-DSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRS 678
R ++ ++ + R R + R R + +R+R + + R+ + R
Sbjct: 393 REREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLRE 452
Query: 679 ERS 681
+ +
Sbjct: 453 KEA 455
Score = 32.3 bits (72), Expect = 1.5
Identities = 23/110 (20%), Positives = 44/110 (40%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
E++ R+ R + + RE + R R +RER + ++ ED ERR
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSR 673
++ + ++ + R R+ + ER ERR +++ R
Sbjct: 446 LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 79.0 bits (193), Expect = 1e-14
Identities = 57/207 (27%), Positives = 112/207 (54%), Gaps = 31/207 (14%)
Query: 243 GEDGKAVACNIKVSFDSTK---HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
G++ ++V+ ++ + + L+ +K + +K+QE E++ +EQ+ + +E EE+
Sbjct: 332 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 300 RAEERKQKELEEL-----ERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE 354
R +E K + EE+ E+ R++EE + ++E+K R +E +K+ + + EE+ QE
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 355 KIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQK-EEKLRLQQQEERRRLQEAE 413
KI+ +E K R + K+REQE++ E++ ++ +QEE+ R QE +
Sbjct: 452 KIREQEEK-------------------RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 414 LRRVEEE---KERALGLQRKERELRER 437
+R EE+ +E + Q K RE +R
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKR 519
Score = 79.0 bits (193), Expect = 1e-14
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 29/197 (14%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA-----EERQRAEERKQKELEEL----ERERKRE 319
+K + + +K QE E+ RE++KR+E+EA EE+ R +E K +E EE E + +
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 320 EKLRKREQKQRDRELRRNQKKLEKL-----QAEEQKQLQEKIKLEERKLLLAQRNL---- 370
EK+R+ E++Q E+ R ++K+ + Q E+ + +EKI+ +E K+ + +
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 371 QSIRLIAELLSRAKAVKLREQEQK----EEKLR-----LQQQEERRRLQEAELRRVEEE- 420
+ IR E + R + K+REQE+K EEK+R Q+QEE+ QE ++ EE+
Sbjct: 571 EKIREQEEKVWRQEE-KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Query: 421 KERALGLQRKERELRER 437
+E+ ++R+E ++RE+
Sbjct: 630 QEQEEKMRRQEEKIREQ 646
Score = 77.8 bits (190), Expect = 3e-14
Identities = 65/227 (28%), Positives = 122/227 (53%), Gaps = 46/227 (20%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKEL--------EELERERKREE 320
+K + +K+ E E+ REE+KR+E+E RQ + R+Q+E+ E+ E+ RK+EE
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 321 KLRKREQKQRDRE--LRRNQKKL-----------EKLQAEEQK---------QLQEKIKL 358
K+ ++E+K D+E +R ++K+ EK++ +E+K + +EK+
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 359 EERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQK----EEKLR-----LQQQEERRRL 409
+E K+ + +Q E R + K+REQE+K EEK+R +Q+QEE+
Sbjct: 618 QEEKMCEQEEKMQE----QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 410 QEAELRRVEEE-KERALGLQRKERELRERLLSILLSKKPDDSHTHDE 455
QE ++ EE+ +E+ ++R+E ++ E+ + L ++ + H E
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQ--EVRLRQQEEKMQEHQE 718
Score = 75.1 bits (183), Expect = 2e-13
Identities = 57/185 (30%), Positives = 113/185 (61%), Gaps = 28/185 (15%)
Query: 270 KRQLERQKLQELEQQREEQKRRE----KEAEERQRAE-----ERKQKELEELERERKR-- 318
+ Q E+ + QE + R+E+K E +E E+RQ E E K +E EE+ R++++
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 319 --EEKLRKREQKQRDRELRRNQKKLEKLQAEEQK--QLQEKIKLEERKLLLAQRNLQSIR 374
EEK+RK+E+K +E + + ++ EK++ +E+K + +EKI+ +E K+ + ++
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQE-EKIREQEEKVWRQEEKIREQEEKIREQEEKIRE-- 603
Query: 375 LIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKER 432
E +++ + K+ EQE+K E++ ++Q+QEE+ R QE ++R E+EK+ ++ +E
Sbjct: 604 --QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR--EQEKK----IREQEE 655
Query: 433 ELRER 437
++RE+
Sbjct: 656 KIREQ 660
Score = 72.4 bits (176), Expect = 1e-12
Identities = 48/179 (26%), Positives = 109/179 (60%), Gaps = 13/179 (7%)
Query: 262 HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEK 321
H + I+K++ + + +E +EE+ R ++E RQ + R+Q+ E+ R++EEK
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE-----EKIREQEEK 600
Query: 322 LRKREQKQRDRELRRNQKKLEKLQAEEQKQLQ-EKIKLEERKLLLAQRNLQSIRLIAELL 380
+R++E+ +++E + +++ + + EE+ Q Q EK++ +E K+ ++ ++ E
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE----QEEK 656
Query: 381 SRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRE 436
R + ++EQE+K E++ ++ +QEE+ + QE ++RR EE+ E+ + L+++E +++E
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Score = 72.0 bits (175), Expect = 2e-12
Identities = 53/187 (28%), Positives = 106/187 (56%), Gaps = 22/187 (11%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA--EERQRAEERKQKELEELERERKREEKLRKRE 326
K+ ++ RQ +E+ ++EE+ RR++E E+ ++ E ++K + E E+ R++EEK R+ E
Sbjct: 408 KEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKIRELEEK-MHEQEKIREQEEK-RQEE 463
Query: 327 QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAV 386
+K R++E R+ Q+ Q E+ ++ +EKI+ +E K+ + + I E R +
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 387 KLREQEQK--------EEKLRLQQQEERRRLQEAELRRVEEE--------KERALGLQRK 430
++ QE+K +K ++ +QEE+ R QE ++ R EE+ +E+ + R+
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 431 ERELRER 437
E ++RE+
Sbjct: 584 EEKIREQ 590
Score = 69.3 bits (168), Expect = 1e-11
Identities = 37/162 (22%), Positives = 101/162 (62%), Gaps = 6/162 (3%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK-----REEKLR 323
+K + +K++E E++ Q+ + +E EE+ R +E K +E EE+ +E++ +EEK+
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
++E+K +++E + +++ EK++ +E+K +++ K+ E++ ++ ++ + ++ +
Sbjct: 624 EQEEKMQEQEEKMRRQE-EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Query: 384 KAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERAL 425
+ ++ +E++ + ++ ++ +QE R R QE +++ +E E A+
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 68.2 bits (165), Expect = 2e-11
Identities = 51/198 (25%), Positives = 108/198 (54%), Gaps = 40/198 (20%)
Query: 270 KRQLERQKLQELEQQ------------------------------REEQKRREKEAEERQ 299
KR+LER KL +QQ R Q++ EK + +
Sbjct: 309 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 368
Query: 300 RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE 359
+ +E ++K E+ E+ R++EEK+R++E+K R +E +K+ EK++ +E+ +++ K+
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMR 427
Query: 360 ERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEE 419
++ ++ ++ + IR + E + + K+REQE+K ++ +++E+R+ QEA++ R EE
Sbjct: 428 RQEEMMWEKE-EKIRELEEKMHEQE--KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 420 EKERALGLQRKERELRER 437
+ ++ +E ++RE+
Sbjct: 485 K------IREQEEKIREQ 496
Score = 55.1 bits (131), Expect = 2e-07
Identities = 42/163 (25%), Positives = 84/163 (51%), Gaps = 37/163 (22%)
Query: 254 KVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELE 313
K+ K + + Q E+ QE + +E+K +E+ EE+ R +E K +E E +
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ--EEKMRRQEEKIREQE--K 648
Query: 314 RERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI 373
+ R++EEK+R++E+ +++E EK+ +E+K +++ K++E++
Sbjct: 649 KIREQEEKIREQEEMMQEQE--------EKMWEQEEKMCEQEEKMQEQE----------- 689
Query: 374 RLIAELLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAEL 414
K+R QE+K E+++RL+QQEE+ + + L
Sbjct: 690 ------------EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 52.8 bits (125), Expect = 1e-06
Identities = 57/201 (28%), Positives = 99/201 (49%), Gaps = 29/201 (14%)
Query: 280 ELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQK 339
ELEQ ++K+A+ R E KE + L E R + E K+++ +L+ +
Sbjct: 237 ELEQALSAVATQKKKAD---RYIEELTKERDALSLELYRNT-ITDEELKEKNAKLQEKLQ 292
Query: 340 KLEKLQAEEQKQLQE-KIKLEERKLLLAQRNLQ-------------SIRLIAEL------ 379
+E ++E Q ++E K KLE KLLL Q+ LQ S +L A++
Sbjct: 293 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 352
Query: 380 --LSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELR 435
L++ + K+ QE+K E + ++Q+QEE+ R QE ++R +EEK R E+E +
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE-QEEKMRRQEEMMWEKEEK 411
Query: 436 ERLLSILLSKKPDDSHTHDEL 456
R ++ +K + +E+
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEM 432
Score = 47.0 bits (110), Expect = 6e-05
Identities = 44/202 (21%), Positives = 102/202 (50%), Gaps = 24/202 (11%)
Query: 263 LSDASIKKRQLERQKLQELEQQR--------------EEQKRREKEAEERQRAEERKQKE 308
LS + +K++ +R ++EL ++R EE K + + +E+ + E ++ E
Sbjct: 242 LSAVATQKKKADRY-IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 300
Query: 309 LE----ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLL 364
++ EL+R+ +R + L ++Q Q + + K+L+ + A+ Q Q++E E L
Sbjct: 301 IQLNVKELKRKLERAKLLLPQQQLQAEAD--HLGKELQSVSAKLQAQVEEN---ELWNRL 355
Query: 365 LAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERA 424
Q+ + R ++ + ++ +E++ +E++ ++++QEE+ R QE + EE+ R
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 415
Query: 425 LGLQRKERELRERLLSILLSKK 446
+ ++ E R ++ K+
Sbjct: 416 EEMMWEKEEKMRRQEEMMWEKE 437
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 79.0 bits (193), Expect = 1e-14
Identities = 90/439 (20%), Positives = 185/439 (42%), Gaps = 55/439 (12%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELR- 335
K++ + Q++ E+K RE++ + ++A+ RK KE EELE +K + K ++ ++K + ++
Sbjct: 224 KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS 283
Query: 336 ----------RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
+++K E A E +K K +++K + + + + KA
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 386 VK--LREQEQKEEKLRLQQQEERRRLQEAELRRVEEEK---ERALGLQRKERELRERLL- 439
++ L + +++EE+ + +++E +RL+E E +R EEE+ E+ ++KE+E +ERL
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403
Query: 440 -SILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKE 498
LL+K ++ E L +LQ S +L PK+
Sbjct: 404 EGKLLTKSQREARARAE----------ATLKLLQAQGVEVPSKDSL-----------PKK 442
Query: 499 SPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRV-----VPEDGSPEKRCPGGVLSCIPDN 553
P + + + ++ KEV S + V E G PEK + +
Sbjct: 443 RPIYED------KKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEE 496
Query: 554 NQQPKGIPACEQNVSRKDT-RSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSR 612
+ + G+ E S ++T + E +K + E + + + + E
Sbjct: 497 DTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN----PEEEEEEEEEEEEDEESEEEEE 552
Query: 613 EDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHS 672
E+G + D+ ++ ++ S S+ +R++E R K
Sbjct: 553 EEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRR 612
Query: 673 RHRRRSERSRSRSPSRHRS 691
+RR E S++ + + R+
Sbjct: 613 IEKRRLEHSKNVNTEKLRA 631
Score = 59.3 bits (142), Expect = 1e-08
Identities = 43/173 (24%), Positives = 98/173 (56%), Gaps = 6/173 (3%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
KK++ +++K E E++ +E+K+ +A + +E K EE ER+++ EE+ KR ++
Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAM-QEALAKLKEEEERQKREEEERIKRLEE 371
Query: 329 ---QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
+R E R Q+K E+ + +++K+ +E++K E + L +QR ++ L +A+
Sbjct: 372 LEAKRKEEERLEQEKRER-KKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQG 430
Query: 386 VKLREQEQKEEKLRLQQQEERRRL-QEAELRRVEEEKERALGLQRKERELRER 437
V++ ++ +K + + ++R+++ Q+ E + V E E ++ E+ + E+
Sbjct: 431 VEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEK 483
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/192 (25%), Positives = 97/192 (50%), Gaps = 16/192 (8%)
Query: 269 KKRQLER-QKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
K+ + ER ++L+ELE +R+E++R E+E ER +KQKE E ER +K + L K ++
Sbjct: 359 KREEEERIKRLEELEAKRKEEERLEQEKRER-----KKQKEKERKERLKKEGKLLTKSQR 413
Query: 328 KQRDR-ELRRNQKKLEKLQAEEQKQLQEKIKL-EERKLLLAQRNLQSIRLIAELLSRAKA 385
+ R R E + + ++ + L +K + E++K + L+S + ++E + A
Sbjct: 414 EARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES-KEVSESMELCAA 472
Query: 386 VKLREQ--EQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILL 443
V++ EQ +KEE + EE ++A L + A+ + ++ + I +
Sbjct: 473 VEVMEQGVPEKEETPPPVEPEEEEDTEDAGL-----DDWEAMASDEETEKVEGNKVHIEV 527
Query: 444 SKKPDDSHTHDE 455
+ P++ +E
Sbjct: 528 KENPEEEEEEEE 539
Score = 34.3 bits (77), Expect = 0.40
Identities = 76/465 (16%), Positives = 179/465 (38%), Gaps = 85/465 (18%)
Query: 256 SFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERE 315
S DSTK D ++E + ++ ++ + +++KE +++ E+ KELEEL E
Sbjct: 9 SEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLE 68
Query: 316 ----------------RKREEKLRKREQKQRDRELRR------NQKKLEKLQAEEQKQLQ 353
EE+ +++K++ ++ ++ + ++LE ++ +K +
Sbjct: 69 AQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAK 128
Query: 354 EKI-------------KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ--------E 392
K+ KL ++ AQ++ + E +K +K R + +
Sbjct: 129 PKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGD 188
Query: 393 QKEEKLRLQQQEERRRLQEA---------------ELRRVEEEKERALGLQRKERELRER 437
+ +E L+ ++ +++ + + +++ V ++K +RK+R+ +
Sbjct: 189 ESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKA 248
Query: 438 LLSILLSKKPDDSHTHDELGVAHAD--LLQPVLDILQTVSSGCVSATTLHPLGGQPPAGA 495
L L K+ ++ D+ + + + TV +G + A+ + A
Sbjct: 249 KLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPAS-------EEKAET 301
Query: 496 PKESPAHPEADGAPKSVNGSVAE-------------EAPCKEVQSSCRVVPEDGSPEKRC 542
P + E D K E +A K +Q + + E+ +KR
Sbjct: 302 PTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKRE 361
Query: 543 PGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRE 602
+ + + + K EQ +++ + +++K +E K G+ + R
Sbjct: 362 EEERIKRLEELEAKRKEEERLEQ--EKRERKKQKEKERKERLKKEGKLLTKSQREARARA 419
Query: 603 RSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSR 647
+ + ++ P K+ P K+ Y+D ++R P S+
Sbjct: 420 EATLKLLQAQGVEVPSKDSLPKKRPIYED---KKRKKIPQQLESK 461
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 78.2 bits (191), Expect = 2e-14
Identities = 46/179 (25%), Positives = 112/179 (62%), Gaps = 6/179 (3%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER-KREEKLR 323
+ ++K++ + QK +E +++EEQ R ++E Q + KQKE E E + ++EE++R
Sbjct: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
++E++ R++E + +++ + + EEQ QE+ E+++ + Q+ Q + ++ +
Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE-QMWKQEEQMGEQE 358
Query: 384 KAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEE---EKERALGLQRKE-RELRERL 438
+ ++ +E++ ++++ ++++QEE+ R QE ++R+ EE E++ +G Q+++ RE E++
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417
Score = 68.2 bits (165), Expect = 2e-11
Identities = 45/188 (23%), Positives = 107/188 (56%), Gaps = 27/188 (14%)
Query: 270 KRQLERQKLQELEQQREEQKRREKE-----AEERQRAEERKQKELEELERERKREEKLRK 324
+++ + QK +E ++EEQ R+++E E+ Q+ EE+ QK+ E++ RK+EE++R+
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM---RKQEEQMRE 266
Query: 325 REQKQRDRE----LRRNQKKLEKLQAEEQKQLQE---------------KIKLEERKLLL 365
+E++ R++E ++ Q + E+ E+++Q++E + ++ E++ +
Sbjct: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
Query: 366 AQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERAL 425
++ Q ++ + + + +E++ E++ ++Q+QEE+ R QE ++R+ EE+ +
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Query: 426 GLQRKERE 433
RK+ E
Sbjct: 387 EQMRKQEE 394
Score = 68.2 bits (165), Expect = 2e-11
Identities = 38/177 (21%), Positives = 104/177 (58%), Gaps = 12/177 (6%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
++ Q+++Q+ Q EQ+ + +K+ E+ E+ ++ ++++++ ++ E+ RK+EE++R++E++
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNL----QSIRLIAELLSRAK 384
R++E + ++K + Q E+ + +E+++ +E ++ + + + +R E + + +
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
Query: 385 AVKLREQEQKEEKL--------RLQQQEERRRLQEAELRRVEEEKERALGLQRKERE 433
++EQ E+ ++ +QEE+ + QE ++R+ EE+ + RK+ E
Sbjct: 331 EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
Score = 64.7 bits (156), Expect = 3e-10
Identities = 40/163 (24%), Positives = 96/163 (58%), Gaps = 5/163 (3%)
Query: 272 QLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRD 331
Q+ Q+ Q EQ+ + +++ + E+ + E++++ E+ E+ +K+EE++ ++E++ R
Sbjct: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231
Query: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
+E + +++ + + EEQ Q QE+ ++ + + Q + +R E + + K +E+
Sbjct: 232 QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE--EQMREQEEQMLKQKEQTEQEE 289
Query: 392 EQKEEKLRLQQQEERRRLQEAELRRVEE---EKERALGLQRKE 431
+ E++ ++++QEE+ R QE ++R EE E+E +G Q ++
Sbjct: 290 QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQ 332
Score = 62.8 bits (151), Expect = 1e-09
Identities = 42/173 (24%), Positives = 104/173 (60%), Gaps = 16/173 (9%)
Query: 271 RQLERQKLQELEQQREEQKR-REKEAEERQRAEERKQKELEELERERK---REEKLRKRE 326
R+ E Q ++ Q RE++ + RE+E + R++ + ++E + E+E + +EE+++K+E
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
Query: 327 QK--QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
++ +++ ++R+ ++++ + + + QKQ ++ K EE+ ++ + +R E + +
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM----RKQEEQMREQEEQMREQE 275
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
L+++EQ E++ + +QEE+ R QE ++R EE+ ++ +E ++RE+
Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ------MREQEEQMREQ 322
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/165 (25%), Positives = 95/165 (57%), Gaps = 9/165 (5%)
Query: 271 RQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQR 330
R+ E Q L++ EQ +E++ E+E + R++ E+ +++E E+ R++EE++R++E++
Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQE----EQMREQEEQMREQEEQMG 327
Query: 331 DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAV--KL 388
+E + ++K + + +EQ QE+ E+ + + Q+ + +R E + + + K
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM--QKQEEQVRKQEEQMRKQEEQMRKQ 385
Query: 389 REQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERE 433
EQ +K+E+ ++ +Q+E+ Q+ ++R EE+ RK+ E
Sbjct: 386 EEQMRKQEE-QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 60.8 bits (146), Expect = 4e-09
Identities = 39/166 (23%), Positives = 99/166 (59%), Gaps = 6/166 (3%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERE-----RKREEKLRKREQKQRD 331
+++E E Q EQ+ + +E E + R +E + +E E RE R++E ++R++E + +
Sbjct: 137 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGE 196
Query: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
+E + +++ + + EEQ Q QE+ ++ E++ + ++ Q ++ + + V+ +E+
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEE-QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255
Query: 392 EQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ ++++ ++++QEE+ R QE ++ + +E+ E+ +E ++RE+
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/174 (24%), Positives = 101/174 (58%), Gaps = 10/174 (5%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKREQKQRDRE 333
+++E E Q EQ+ + +E E + R +E + +E E RE++ RE++ + REQ+ + RE
Sbjct: 116 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 175
Query: 334 LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
++ E E++ Q+ E+ ++ E++ + ++ Q + ++ + + ++ +E++
Sbjct: 176 QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKK 446
E++ ++Q+QEE+ + QE ++R+ EE+ ++ +E ++RE+ +L K+
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQ------MREQEEQMREQEEQMLKQKE 283
Score = 57.0 bits (136), Expect = 6e-08
Identities = 40/165 (24%), Positives = 100/165 (60%), Gaps = 11/165 (6%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERE-----RKREEKLRKREQKQRD 331
+++E E Q EQ+ + +E E + R +E + +E E RE R++E ++R++E + R+
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
+E + +++ + + EEQ QE+ ++++++ + ++ Q + ++ + + V+ +E+
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEE-QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
Query: 392 EQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
+ ++++ ++++QEE+ R QE ++R EE+ L++KE+ +E
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQM-----LKQKEQTEQE 288
Score = 53.9 bits (128), Expect = 5e-07
Identities = 40/166 (24%), Positives = 97/166 (58%), Gaps = 5/166 (3%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKREQKQRDRE 333
+++E E Q EQ+ + +E E + R +E + +E E RE++ RE++ + REQ+ + RE
Sbjct: 102 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 161
Query: 334 LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
++ E E++ Q++E+ ++ E++ + ++ Q ++ + + ++ +E++
Sbjct: 162 QEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQ 221
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRK-ERELRER 437
E++ ++++QEE+ QE ++++ EE+ ++ RK E ++RE+
Sbjct: 222 MGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
Score = 52.4 bits (124), Expect = 1e-06
Identities = 40/166 (24%), Positives = 97/166 (58%), Gaps = 5/166 (3%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKREQKQRDRE 333
+++E E Q EQ+ + +E E + R +E + +E E RE++ RE++ + REQ+ + RE
Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147
Query: 334 LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
++ E E++ Q++E+ ++ E++ + ++ Q ++ + + +E++
Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ 207
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRER 437
E++ ++Q+QEE+ QE ++R+ EE+ E+ +Q++E +++++
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Score = 51.6 bits (122), Expect = 2e-06
Identities = 38/166 (22%), Positives = 98/166 (59%), Gaps = 5/166 (3%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKREQKQRDRE 333
+++E E Q EQ+ + +E E + R +E + +E E RE++ RE++ + REQ+ + RE
Sbjct: 95 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 154
Query: 334 LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
++ E E++ Q++E+ ++ E++ + ++ Q ++ + + + +E++
Sbjct: 155 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ 214
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKERELRER 437
++++ ++ +QEE+ R QE ++ EE+ +++ +Q++E ++R++
Sbjct: 215 MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
Score = 50.1 bits (118), Expect = 7e-06
Identities = 45/182 (24%), Positives = 98/182 (53%), Gaps = 15/182 (8%)
Query: 270 KRQLERQKL--------QELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---R 318
KR+LE K+ +E E Q EQ+ + +E E + R +E + +E E RE++ R
Sbjct: 38 KRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 97
Query: 319 EEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIA 377
E++ + REQ+ + RE ++ E E++ Q++E+ ++ E++ + ++ Q
Sbjct: 98 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 157
Query: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVE---EEKERALGLQRKEREL 434
++ + V+ +E + +E++ ++++QE + R QE ++ E E+E +G Q ++ +
Sbjct: 158 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQK 217
Query: 435 RE 436
+E
Sbjct: 218 QE 219
Score = 49.3 bits (116), Expect = 1e-05
Identities = 39/161 (24%), Positives = 88/161 (54%), Gaps = 4/161 (2%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKREQKQRDRE 333
+++E E Q EQ+ + +E E + R +E + +E E RE++ RE++ + REQ+ + RE
Sbjct: 74 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 133
Query: 334 LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
++ E E++ Q++E+ ++ E++ + ++ Q ++ + V+ +E +
Sbjct: 134 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 193
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERE 433
E++ ++ +QEE+ QE ++++ EE+ RK+ E
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234
Score = 48.1 bits (113), Expect = 3e-05
Identities = 39/166 (23%), Positives = 94/166 (56%), Gaps = 5/166 (3%)
Query: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKREQKQRDRE 333
+++E E Q EQ+ + +E E + R +E + +E E RE++ RE++ + REQ+ + RE
Sbjct: 60 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 119
Query: 334 LRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
++ E E++ Q++E+ ++ E++ + ++ Q ++ + V+ +E +
Sbjct: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 179
Query: 393 QKEEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRER 437
+E++ ++++QE + QE ++ EE+ E+ +Q++E ++ E+
Sbjct: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/81 (28%), Positives = 51/81 (62%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
+++ + QK +E +++EEQ R+++E +Q + RKQ+E ++E+ E+K + REQ++
Sbjct: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
Query: 330 RDRELRRNQKKLEKLQAEEQK 350
+ E + +K E+ E+++
Sbjct: 416 QMGEQKEQMRKQEEHMGEQKE 436
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/94 (30%), Positives = 59/94 (62%), Gaps = 9/94 (9%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
+K Q+ +Q+ Q EQ+ + QK+ EE+ R +E + ++ E E+ RK+EE++RK+E++
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQ-----EEQVRKQEEQMRKQE--EQMRKQEEQMRKQEEQ 395
Query: 329 QRDRELRRNQKKLEKLQAEEQ--KQLQEKIKLEE 360
+++ + ++K + + EEQ +Q ++ K EE
Sbjct: 396 MGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/87 (27%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
K++ + + +E Q++EEQ R+++E +Q + RKQ+E + E+ E+K + EQK+
Sbjct: 349 KQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKE 408
Query: 330 RDRELRRNQ-KKLEKLQAEEQKQLQEK 355
+ RE ++ E+++ +E+ ++K
Sbjct: 409 QMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/78 (25%), Positives = 51/78 (65%), Gaps = 2/78 (2%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKEL--EELERERKREEKL 322
+ ++K++ + +K +E +++EEQ R+++E +Q + +QKE E+ E+ R++EE++
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417
Query: 323 RKREQKQRDRELRRNQKK 340
+++++ R +E ++K
Sbjct: 418 GEQKEQMRKQEEHMGEQK 435
Score = 40.4 bits (93), Expect = 0.006
Identities = 38/170 (22%), Positives = 94/170 (55%), Gaps = 6/170 (3%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQK-ELEEL---ERERKREEKLRKREQKQ 329
E K + E Q E Q +++E + +E K+K E +++ + + RE++ + REQ+
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 330 RDRELRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
+ RE ++ E E++ Q++E+ ++ E++ + ++ Q ++ + V+
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 389 REQEQKEEKLRLQQQEERRRLQEAELRRVE-EEKERALGLQRKERELRER 437
+E + +E++ ++++QE + R QE ++R E + +E+ ++ +E ++RE+
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 176
Score = 36.2 bits (82), Expect = 0.11
Identities = 17/65 (26%), Positives = 40/65 (61%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
+ ++K++ + +K +E +++EEQ +KE Q+ + R+Q+E ++E+ R+++
Sbjct: 372 EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Query: 325 REQKQ 329
EQK+
Sbjct: 432 GEQKE 436
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 77.8 bits (190), Expect = 3e-14
Identities = 54/172 (31%), Positives = 103/172 (59%), Gaps = 9/172 (5%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEEL--ERERKREEKLRKREQKQRD 331
+ +K+QE E++ +EQ+ + E EE+ + +E K E EE E+E K E+ R EQK++
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
E + Q++ EK+Q +E+K + E+ K+E++ ++ ++ E R + K+RE+
Sbjct: 668 WEHEKMQEQ-EKMQEQEEK-IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 392 EQ--KEEKLRLQQQEERRRLQEAELRRVEE---EKERALGLQRKERELRERL 438
E+ +E++ ++Q+QEE+ + QE E+ EE E+E + Q++ E +E+L
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Score = 77.0 bits (188), Expect = 5e-14
Identities = 52/168 (30%), Positives = 103/168 (61%), Gaps = 10/168 (5%)
Query: 276 QKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELR 335
+K QE E++ +Q+ + +E EER R E+K +E EE+ RE+ EEK++++E+K +++E +
Sbjct: 569 KKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQ--EEKMQEQEEKMQEQEEK 625
Query: 336 RNQKKLEKLQAEEQKQLQEKIKL--EERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQ 393
+++ EK+Q +E+K +++ K+ +E K+ QR + + E + K++EQE+
Sbjct: 626 MWEQE-EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Query: 394 K---EEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKERELRER 437
K +EK+ + QE+ ++ + E R EE +ER ++ +E +RE+
Sbjct: 685 KIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Score = 76.3 bits (186), Expect = 9e-14
Identities = 58/199 (29%), Positives = 114/199 (57%), Gaps = 33/199 (16%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
D +++++ ER + QE ++ E+ R EK+ +E+++ ++++++E ER R+RE+K+R+
Sbjct: 403 DERLREKE-ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQ-----------SI 373
E+ R++E + QK+ E + +E+K+ Q++ E+++ L Q +Q I
Sbjct: 462 EEETMREQE-EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 374 RLIAELLSRAKAV----KLREQE----QKEEKLRLQQ-----QEER--RRLQEAELRRVE 418
R E+ + K + K+REQE ++EEK+R Q+ QEER ++ QE E + +
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 419 EEKERALGLQRKERELRER 437
+E++ R+E +RER
Sbjct: 581 QEEK-----MREEERMRER 594
Score = 75.1 bits (183), Expect = 2e-13
Identities = 50/169 (29%), Positives = 105/169 (62%), Gaps = 10/169 (5%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
++ E++K+QE E++ EQ++ EK+ +E+++ + Q+++ E E R+RE+K+R+ E+
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK-KTWDQEKMREEESMREREKKMREEEEMM 729
Query: 330 RDRELRRNQKKLEKLQAEEQK--QLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVK 387
R++E + Q++ EK+Q +E++ + +EK+ +E K+ QR + + E + K
Sbjct: 730 REQE-EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Query: 388 LREQEQK--EEKLRLQQQEERRRLQEAELRRVEE----EKERALGLQRK 430
+ EQE+K +++ +++ QEE+ R QE ++R EE ++E+ G + K
Sbjct: 789 IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK 837
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/187 (26%), Positives = 113/187 (60%), Gaps = 21/187 (11%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERK----QKELEELERERKREEKLRK 324
KK + + +K+ E++ EQ+ + +E EE+ +E++ +KEL E E+E + +++LR+
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELL---- 380
+E++ +++E + +++ EK++ +E+K +++ +L E++ + ++ Q +R E +
Sbjct: 346 QEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQE-QKMRDQEERMWEQD 403
Query: 381 --SRAKAVKLREQEQ--------KEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRK 430
R K ++REQE+ +EEK ++Q+QE++ R QE +++ E +ER ++ +
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEK-KMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 431 ERELRER 437
E +RE+
Sbjct: 463 EETMREQ 469
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/175 (28%), Positives = 103/175 (58%), Gaps = 7/175 (4%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK---REEKLRKR 325
K+ + + QK+++ E++ EQ R +E EER R +E+ +++E++ E+K +E+K R +
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAK 384
E+K ++ E R ++K + + E ++ +EK+ K EE ++ Q RL + +
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 385 AVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K++EQE+K E++ +++ QEE QE ++ R E+ +E+ + +E ++R++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWG-QEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/181 (25%), Positives = 106/181 (58%), Gaps = 12/181 (6%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
K R+ E Q ++ E+ R+++++ + E ++ + ++K+ + E + + EE++R+RE+K
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 329 QRDRE--LRRNQKKL----EKLQAEEQK--QLQEKIKLEERKLLLAQRNL--QSIRLIAE 378
R+ E +R ++K+ EK+Q +E+K + +EK++ +E K+ + + Q ++ +
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 379 LLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQ--RKERELRE 436
+ KL E E+ +E+ ++Q+QEE+ QE ++ +E++++ + R+E +RE
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE 717
Query: 437 R 437
R
Sbjct: 718 R 718
Score = 73.6 bits (179), Expect = 6e-13
Identities = 53/172 (30%), Positives = 103/172 (59%), Gaps = 15/172 (8%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEE--RKQKELEELERERKREEKLRKREQ 327
+ Q ++ + QE + R+E++ RE+E + R++ E+ R++K L E E+E + +EK REQ
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK-ELREQ 340
Query: 328 KQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVK 387
K ELR ++++++ Q E+ + +EK++ +E K+ + L E R + K
Sbjct: 341 K----ELREQEEQMQE-QEEKMWEQEEKMREQEEKMWRQEERLWE----QEKQMREQEQK 391
Query: 388 LREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+R+QE++ E+ RL+++EER R QE +VE+ +E +Q +E++ R++
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK-KMQEQEKKTRDQ 442
Score = 72.8 bits (177), Expect = 1e-12
Identities = 51/176 (28%), Positives = 102/176 (57%), Gaps = 16/176 (9%)
Query: 275 RQKLQELEQQRE--EQKRREKEAEERQRAEERKQKELEEL-----ERERKREEKLRKREQ 327
R++ +EL +Q+E EQ+ + +E EE+ +E K +E EE ER ++E+++R++EQ
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 328 KQRDRELR------RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLS 381
K RD+E R R ++K E+++ +E+ Q + EE+K+ Q + R E +
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM---QEQEKKTRDQEEKMQ 447
Query: 382 RAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ ++ RE++ +EE+ +++QEE+ + QE + EE++ + L ++ +L E+
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Score = 72.4 bits (176), Expect = 1e-12
Identities = 53/173 (30%), Positives = 102/173 (58%), Gaps = 5/173 (2%)
Query: 269 KKRQLERQKLQELEQQRE-EQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
KK + + +K+QE E+ RE E+K RE+E R++ E+ +++E E+E K ++ R EQ
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 328 KQRDRELRRNQKKLEKLQAEEQK-QLQEKIKLEERKLLLAQ--RNLQSIRLIAELLSRAK 384
K++ E + Q++ EK+ +E+K + QE++ +E+K+ + R + E R +
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
K+ +QE++ EK + Q+QE++ QE ++R E +ER ++ +E +RE+
Sbjct: 557 EQKMWDQEERMEK-KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Score = 71.2 bits (173), Expect = 3e-12
Identities = 43/173 (24%), Positives = 105/173 (60%), Gaps = 5/173 (2%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKE---LEELERERKREEKLRK 324
++ L+ + ++ E+ RE++K+ K+ E+ R EER +++ + E E + R+EK R
Sbjct: 265 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEK-RL 323
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
REQ++ RE + ++ ++L+ +E++ +++ K+ E++ + ++ + R L + K
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 383
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
++ +EQ+ ++++ R+ +Q+ER R +E +R E+ E+ + R+E++++E+
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ-VEKMREEKKMQEQ 435
Score = 70.9 bits (172), Expect = 4e-12
Identities = 52/190 (27%), Positives = 106/190 (55%), Gaps = 30/190 (15%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERK-----------QKELEELERE-R 316
+K E+++L+E E+Q +EQ+ + E EE+ R +E K +K++ E E++ R
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 317 KREEKL-----RKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQ 371
+EE++ R RE+++R RE + +++EK++ E++ Q QEK ++ + + + ++
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 372 SIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEA---ELRRVEEEKERALGLQ 428
R K ++ E+ +E++ ++Q+QEE QE + +R+ E+KE+ L Q
Sbjct: 454 ---------EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LWEQ 503
Query: 429 RKERELRERL 438
K +E E++
Sbjct: 504 EKMQEQEEKI 513
Score = 70.1 bits (170), Expect = 7e-12
Identities = 50/170 (29%), Positives = 93/170 (54%), Gaps = 18/170 (10%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKR---------- 318
+K Q + +K+QE E++ EQ+ + +E EE+ +E K E EE E++R
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 319 EEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAE 378
EK++++E+ Q E Q+K+EK E++K+ ++ K+ E + + R + E
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE---SMREREKKMREEE 726
Query: 379 LLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEA---ELRRVEEEKER 423
+ R + K++EQE+K E++ + +QEE+ QE E +R+ E+KE+
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Score = 69.7 bits (169), Expect = 9e-12
Identities = 54/184 (29%), Positives = 112/184 (60%), Gaps = 19/184 (10%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEE-RKQKELEELERE-RKREEKLRKREQ 327
+ Q + + QE + R+E++ RE+E E R++ +E R+QKEL E E + +++EEK+ ++E+
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362
Query: 328 KQRDRELR--RNQKKL----EKLQAEEQKQLQEKIKL---EERKLLLAQRNLQSIRLIAE 378
K R++E + R +++L ++++ +EQK ++ ++ +ER +R + ++ +
Sbjct: 363 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422
Query: 379 LLSRAKAVKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKERE 433
+ + K++EQE+K EEK+ Q+EER R +E ++R EE +E+ +Q++E
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKM---QEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 434 LRER 437
+ E+
Sbjct: 480 MWEQ 483
Score = 69.3 bits (168), Expect = 1e-11
Identities = 61/199 (30%), Positives = 100/199 (50%), Gaps = 37/199 (18%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEA-----EERQRAEERKQKELEELERERK-----R 318
KK Q + +K + E+ REE+ RE+E EE R +E K +E EE +E++ +
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ 753
Query: 319 EEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAE 378
EEK+ ++E+K +++ QK EKL E+ Q QEKI +E K+ + ++ E
Sbjct: 754 EEKMWEQEEKMWEQQRLPEQK--EKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG----QE 807
Query: 379 LLSRAKAVKLREQEQK------------------EEKLRLQQQEERRRLQ-EAELRRVEE 419
R + K+R QE+K EEK+ Q+++ ++Q + E R +E
Sbjct: 808 EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867
Query: 420 EKERALGLQRKERELRERL 438
EK R G + K RE E++
Sbjct: 868 EKMR--GQEEKMREQEEKM 884
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/175 (28%), Positives = 104/175 (59%), Gaps = 9/175 (5%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEE---RKQKELEELERERKREEKLRKR 325
K++ E++K+QE E++ EQ+ + ++ EE E+ R++K E+ ++ ++EEK+R +
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 326 EQKQRDRELRRNQK--KLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
EQK D+E R +K + EK +++++++E+ ++ ER+ + R + + E +
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM--REEEEMMREQEEKMQE 614
Query: 384 KAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
+ K++EQE+K E++ ++Q+QEE+ QE ++ EE+ L ++ +L E
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Score = 68.2 bits (165), Expect = 2e-11
Identities = 53/199 (26%), Positives = 113/199 (56%), Gaps = 30/199 (15%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEER----QRAEERKQKELEELERERKREEKLRK 324
KK + E + ++E E++ ++Q+ E EE+ QR E+K+K L E E+ +++EEK+ +
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LWEQEKMQEQEEKIWE 515
Query: 325 REQKQRDRELRRNQKKL----EKLQAEEQK--QLQEKIKLEERKLLLAQRNL-------- 370
+E+K RD+E Q+K EK++ +E + + +EK++ +E+K+ + +
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 371 -----QSIRLIAELLSRAKAVKLREQEQ--KEEKLRLQQQEERRRLQEAEL----RRVEE 419
Q ++ E R + K+RE+E+ +E++ ++Q+QEE+ + QE ++ +++E
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635
Query: 420 EKERALGLQRKERELRERL 438
++E+ + K E E++
Sbjct: 636 QEEKMWEQEEKMWEQEEKM 654
Score = 67.8 bits (164), Expect = 3e-11
Identities = 56/176 (31%), Positives = 99/176 (56%), Gaps = 19/176 (10%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
KR+LER K + Q + EE R +E+K ++ EE + ++EE+LR++E K
Sbjct: 252 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE--KMWRQEERLREQEGKM 309
Query: 330 RDRE--LRRNQKKL---EKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
R++E + R +K+L EK E++K+L+E+ +L E++ + ++ E +
Sbjct: 310 REQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQ---------EEKMWEQ 360
Query: 385 AVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEK-ERALGLQRKERELRER 437
K+REQE+K ++ RL +QE++ R QE ++R EE E+ L+ KE +RE+
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 416
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/191 (26%), Positives = 102/191 (53%), Gaps = 30/191 (15%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEEL-----ERERKREEKLRKREQK 328
+ +K++E E++ Q+ R E E++ R +E+K ++ EE ER R++EE++R++E+
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 329 QRDRELRRNQKKLEKLQA-----EEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
E R +KK+++ + EE+ Q +E+I+ E+K+ + ++ E +
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE----QEEKMQK 475
Query: 384 KAVKLREQEQKE--------------EKLRLQQQEERRRLQEAELRRVEE--EKERALGL 427
+ + EQE+KE E+ ++Q+QEE+ QE ++R EE +E+ +
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 535
Query: 428 QRKERELRERL 438
Q K RE +++
Sbjct: 536 QEKMREQEDQM 546
Score = 67.4 bits (163), Expect = 4e-11
Identities = 51/178 (28%), Positives = 106/178 (59%), Gaps = 19/178 (10%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEER---KQKELEELERERKREEKLRKREQKQR 330
+++KL E E+ +EQ+ + E EE+ R +E ++K++ E+ R++E+++ ++E+K R
Sbjct: 496 QKEKLWEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 331 DRELRR--NQKKLEKLQAEEQKQL---QEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
D+E + ++++EK E++K+ +EK++ EER R + E + R +
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER-----MREREKKMREEEEMMREQE 609
Query: 386 VKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEE---EKERALGLQRKERELRERL 438
K++EQE+K E++ ++ +QEE+ + QE ++ EE E+E + Q++ E +E+L
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Score = 67.0 bits (162), Expect = 6e-11
Identities = 52/208 (25%), Positives = 115/208 (55%), Gaps = 28/208 (13%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAE----------------ERQRA 301
+ K D K ++ ER + +E + + EE+ RE+E + ++QR
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Query: 302 EERKQKELEELERERKREEKLRKREQKQRDRELRRNQKK----LEKLQAEEQK--QLQEK 355
E+K+K L E E+ +++EEK+ ++E+K RD+E Q+K EK++ +E + + +EK
Sbjct: 494 PEQKEK-LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 356 IKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQ-KEEKLRLQQQEERRRLQEAEL 414
++ +E+K+ + ++ E + + K+RE+E+ +E + +++++EE R QE ++
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 415 R----RVEEEKERALGLQRKERELRERL 438
+ +++E++E+ + K +E E++
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Score = 65.1 bits (157), Expect = 2e-10
Identities = 52/195 (26%), Positives = 105/195 (53%), Gaps = 23/195 (11%)
Query: 254 KVSFDSTKHLSDASIKKRQL----ERQKLQELEQQREEQKRREKEAEERQRAEERKQKEL 309
K ++D K + S+++R+ E + ++E E++ +EQ+ + +E EE +E K E
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 310 EELERERKR----EEKLRKREQKQRDRELRRNQKKL----EKLQAEEQKQL--QEKIKLE 359
EE E++R +EKL + E+ Q ++ ++K+ EK++ +E+K +EK++ +
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Query: 360 ERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR---- 415
E K+ + + E + K+ QE+K E+ ++Q QEE+ R QE ++R
Sbjct: 821 EEKMWGQEEKMWG----QEEKMWGQEEKMWGQEEKMEE-KMQGQEEKMREQEEKMRGQEE 875
Query: 416 RVEEEKERALGLQRK 430
++ E++E+ G + K
Sbjct: 876 KMREQEEKMRGQEEK 890
Score = 64.3 bits (155), Expect = 4e-10
Identities = 53/185 (28%), Positives = 104/185 (56%), Gaps = 25/185 (13%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKE---AEERQRAEERKQKELEELERERKREEKLRKR 325
++ ++ Q+ E + Q +E+K ++E EE R E+K +E EE+ RE +EEK++++
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE--QEEKMQEQ 739
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+K +++E +++ EK+ +E+K +++ E+++ L +Q I E +
Sbjct: 740 EEKMQEQEEEMWEQE-EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE-----QE 793
Query: 386 VKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEE----EKERALGLQRK----ERE 433
K+R+QE+K EEK+R QEE+ R QE ++ EE ++E+ G + K E +
Sbjct: 794 EKMRDQEEKMRGQEEKMR--GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 434 LRERL 438
+ E++
Sbjct: 852 MEEKM 856
Score = 58.9 bits (141), Expect = 2e-08
Identities = 50/202 (24%), Positives = 104/202 (51%), Gaps = 41/202 (20%)
Query: 238 KLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEE 297
KL + + N+K + + L A Q++ LQE E R+E++ RE+E +
Sbjct: 233 KLPLAESEKSEIQLNVK---ELKRKLERAKFLLPQVQTNTLQE-EMWRQEEELREQEKKI 288
Query: 298 RQRAEERKQKELEELERERKREEKLRKREQK--QRDRELRRNQKKLEKLQAEEQKQLQEK 355
R++ E+ ++E ER R++E K+R++E+K ++++ LR +K+L E++K+L+E+
Sbjct: 289 RKQEEKMWRQE----ERLREQEGKMREQEEKMWRQEKRLREQEKELR----EQEKELREQ 340
Query: 356 IKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR 415
+L E++ EQ Q++E+ +Q+E+ R +E R
Sbjct: 341 KELREQE---------------------------EQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 416 RVEEEKERALGLQRKERELRER 437
+ E E+ ++ +E+++R++
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQ 395
Score = 57.8 bits (138), Expect = 3e-08
Identities = 46/180 (25%), Positives = 98/180 (54%), Gaps = 20/180 (11%)
Query: 274 ERQKLQELEQQREEQKRREKEAE-----ERQRAEERKQKELEELERERKREEKLRKREQK 328
+ +K+ E E++ EQ+R ++ E E+ + +E+ Q++ E++ + K E+K +++E+K
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
D+E R + E ++ E+K +E+ + E++ + ++ + E+ + + K+
Sbjct: 703 TWDQEKMREE---ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE--KM 757
Query: 389 REQEQKE-EKLRLQQQEER----RRLQEAELRRVEEEK-----ERALGLQRKERELRERL 438
EQE+K E+ RL +Q+E+ ++QE E +EEK E+ G + K R E++
Sbjct: 758 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM 817
Score = 43.9 bits (102), Expect = 5e-04
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 33/119 (27%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELE---------------- 313
++ E++K+ E E++ +Q+ + + EE+ R +E K + EE
Sbjct: 781 EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWG 840
Query: 314 -------RERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQK--QLQEKIKLEERKL 363
+E K EEK++ +E+K R++E EK++ +E+K + +EK++ +E K+
Sbjct: 841 QEEKMWGQEEKMEEKMQGQEEKMREQE--------EKMRGQEEKMREQEEKMRGQEEKI 891
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 77.0 bits (188), Expect = 5e-14
Identities = 95/451 (21%), Positives = 170/451 (37%), Gaps = 39/451 (8%)
Query: 249 VACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKE 308
V I + F + S S ++R L + RE +++E+E +R ER+
Sbjct: 18 VEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDR 77
Query: 309 LEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQR 368
E RE+ R K + ++QRDRE R ++ + + +K+ + + E +R
Sbjct: 78 KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137
Query: 369 NLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQ 428
+ + RE+++ EK R +Q + R+ Q R+ E E+E+
Sbjct: 138 GRD---------RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK----N 184
Query: 429 RKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLG 488
R+ER RER ++ ++ T D H++ + +T + T
Sbjct: 185 RQERRERER-------QREKENKTEDR----HSERGRERERERETETETERKRQTDRERD 233
Query: 489 GQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLS 548
Q +E A E ++ E ++ R + +++
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 549 CIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARR 608
D + K E+ R+ R + + RE + R R T DR K + +R
Sbjct: 294 ---DRETERKRERQRERERERERNRKRERERERERERERQRETE---RDREKERERKRKR 347
Query: 609 ASSREDGRPRKERRPHKKHAYKD-DSPRRRSTSPDHTRSRRSHSKDRHR---RERSRERR 664
+ + R R+ R ++ A ++ + R R R R +DR R RER E+
Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 665 GSASRKHSRHR-----RRSERSRSRSPSRHR 690
R+ + R R SER R R R +
Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREK 438
Score = 76.3 bits (186), Expect = 9e-14
Identities = 51/174 (29%), Positives = 95/174 (54%), Gaps = 19/174 (10%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAE-----ERQRAEERKQKELEELERERKREEKLR 323
+KRQ ++ +E E++RE Q+ RE+E E ER+R ER+++ E ER+R++E + +
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
++ Q + DRE R + + QAE +++ + +R+ QS R E
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERER------------ERDRQSAREREERERDR 392
Query: 384 KAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ +E+E++ EK R Q+E ++ + + R E +ER G +R++++ RER
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER--GREREKQKGRER 444
Score = 74.7 bits (182), Expect = 3e-13
Identities = 100/442 (22%), Positives = 169/442 (38%), Gaps = 61/442 (13%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK 324
DA R+ RQK +E +++ + +R ER+R ++R +K ER+R RE K
Sbjct: 48 DADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE----K 103
Query: 325 REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
++Q DRE R ++K Q E +++ + + + + QR
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE--------------- 148
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLS 444
RE+++ EK R +Q + R+ Q R+ E E+E+ R+ER RER
Sbjct: 149 ----RERQRDAEKERERQTDRERQRQTERNRQKEREREK----NRQERRERER------- 193
Query: 445 KKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPE 504
++ ++ T D H++ + +T + T Q +E A E
Sbjct: 194 QREKENKTEDR----HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 505 ADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACE 564
++ E ++ R + +++ D + K E
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER---DRETERKRERQRE 306
Query: 565 QNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK-RERSRAR-------------RAS 610
+ R+ R + + RE + R R T DR K RER R R R
Sbjct: 307 RERERERNRKRERERERERERERQRETE---RDREKERERKRKRQTEMDRERNRQTGREG 363
Query: 611 SREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSR-RSHSKDRH-RRERSRERRGSAS 668
R+ R R+ R + + ++ R R D + R R KDR +RE ++R
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423
Query: 669 RKHSRHRRRSERSRSRSPSRHR 690
R+ R R R R R + R R
Sbjct: 424 RESERGRERG-REREKQKGRER 444
Score = 62.8 bits (151), Expect = 1e-09
Identities = 44/166 (26%), Positives = 83/166 (50%), Gaps = 21/166 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQK 328
++R+ ER++ ++ E +R+ +K R ERK+K E++RER R+ R Q
Sbjct: 319 RERERERERERQRETERDREKER-----------ERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 329 QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
+R+RE R + + + EE+++ +++ + +ER +R + R + + K
Sbjct: 368 ERERERERERDRQSAREREERERDRDRDRQKER-----ERQTEKDR-----DGQRETEKQ 417
Query: 389 REQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKEREL 434
RE+E+ E R +++ R Q+ R E + +R G QRK L
Sbjct: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 56.2 bits (134), Expect = 1e-07
Identities = 38/136 (27%), Positives = 62/136 (45%), Gaps = 13/136 (9%)
Query: 569 RKDTRSEQDKCNREPSKGRGRATGDGLADR-HKRERSRA-------RRASSREDGRPRKE 620
R+ ++ Q++ RE + + T D ++R +RER R +R + RE R RK
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 621 RRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHR----- 675
R +K A ++ + R + R +DR RR++ RER+ R+ R
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 676 RRSERSRSRSPSRHRS 691
R+ ER R R R R+
Sbjct: 299 RKRERQRERERERERN 314
Score = 53.5 bits (127), Expect = 6e-07
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 5/123 (4%)
Query: 570 KDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAY 629
++T +E ++ R+ + R R +R + +++ RAS RE R ++ R +
Sbjct: 216 RETETETER-KRQTDRERDRQRK---TEREREKQAERERASERETERDKERERERDRDRD 271
Query: 630 KDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRH 689
+D + R D R RR+ R+R R+R R+ +R R R ER R R R
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER-ERERERERERQ 330
Query: 690 RST 692
R T
Sbjct: 331 RET 333
Score = 53.1 bits (126), Expect = 8e-07
Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 12/137 (8%)
Query: 568 SRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRAR--RASSREDGRPRKERRPHK 625
SR+ S++ R + A GD ++ER R R R + RE R R+ RR
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 626 KHAYKD---------DSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASR-KHSRHR 675
+H +D + R R T + R R + RER ER G R + + +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 676 RRSERSRSRSPSRHRST 692
R ER R R R T
Sbjct: 147 RERERQRDAEKERERQT 163
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 12/139 (8%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
++ R + + + RE +GR R T DG +R ++ + R + R R+ R
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQT-DGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRH-----RRERSRERRGSASRKHSRHR--- 675
+K ++ + R+ + R + + ++DRH RER RE RK R
Sbjct: 175 RQKEREREKN-RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 676 --RRSERSRSRSPSRHRST 692
R++ER R + R R++
Sbjct: 234 RQRKTEREREKQAERERAS 252
Score = 48.9 bits (115), Expect = 2e-05
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 23/137 (16%)
Query: 571 DTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYK 630
+ +E+DK RE + R R DR +R++ R R+ + R ++R +K +
Sbjct: 253 ERETERDK-ERERERDRDR-------DRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 631 DDSPRRRSTSPDHTRSR-RSHSKDRHR---------RERSRERRGSASRKHSRH-----R 675
+ R R + R R R ++R R RER R+R+ R+ +R R
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
Query: 676 RRSERSRSRSPSRHRST 692
R++ER R R R R +
Sbjct: 365 RQAERERERERERDRQS 381
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/133 (30%), Positives = 59/133 (44%), Gaps = 18/133 (13%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK-----RERSRARRASSREDGRPR 618
++ R+ R Q + +RE ++ GR G A+R + R+R AR RE R R
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGRE-GRRQAERERERERERDRQSAREREERERDRDR 394
Query: 619 KERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR---RERSRERRGSASRKHSRHR 675
++ ++ KD +R T +R KDR RER RER R+ R R
Sbjct: 395 DRQKERERQTEKDRDGQR------ETEKQREREKDRESERGRERGREREKQKGRERDRER 448
Query: 676 ---RRSERSRSRS 685
R++ R R RS
Sbjct: 449 QTDRQAGRQRKRS 461
Score = 48.1 bits (113), Expect = 3e-05
Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 13/139 (9%)
Query: 564 EQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
E+ R+ R Q + R K R R +R +RER R + + ED + R
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNR--QERRERERQREKE-NKTEDRHSERGRER 212
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSR----------ERRGSASRKHSR 673
++ + ++ R+R T + R R++ + + ER R ER R R
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 674 HRRRSERSRSRSPSRHRST 692
RR+ ER R R R T
Sbjct: 273 DRRQKERERQTDRKRQRRT 291
Score = 47.4 bits (111), Expect = 5e-05
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 7/130 (5%)
Query: 570 KDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAY 629
++ R E+ + RE + R R DRH++ R RE R R+ R +
Sbjct: 62 RERRREKRQTERETDRKRERRREK---DRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
Query: 630 KD---DSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHR-RRSERSRSRS 685
K+ R R T + R R + + RER R+ R+ R R R++ER+R +
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 686 PSRHRSTWNR 695
R ++ R
Sbjct: 179 REREKNRQER 188
Score = 43.5 bits (101), Expect = 7e-04
Identities = 19/76 (25%), Positives = 51/76 (67%), Gaps = 1/76 (1%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELE-ELERERKREEKLR 323
D + + ER++ ++ ++Q+E +++ EK+ + ++ E+++++E + E ER R+R +
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 324 KREQKQRDRELRRNQK 339
K++ ++RDRE + +++
Sbjct: 438 KQKGRERDRERQTDRQ 453
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 77.0 bits (188), Expect = 5e-14
Identities = 60/193 (31%), Positives = 112/193 (58%), Gaps = 21/193 (10%)
Query: 276 QKLQELEQQREEQKRREKEAEERQR---------AEERKQKELEE----LERERKR-EEK 321
+K++E +++R E +R EAEER+R A+ER + E EE ERER+ EE+
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 322 LRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLS 381
R RE+++R E R+ K+ EK AEE+++++E+ E+R QR + + AE
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEE---EKRAAEERQRIKEEEKRAAEERQ 371
Query: 382 RAKAVKLREQEQKEEKLRLQQQEERRRLQEAELR--RVEEEKERALGLQRKERELRERLL 439
RA+A + + + +E+K Q +E++ +QE +++ +VE++ E ++K +E ++L
Sbjct: 372 RARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQE--DKLQ 429
Query: 440 SILLSKKPDDSHT 452
+ +L K+ ++ T
Sbjct: 430 TAVLKKQGEEKGT 442
Score = 67.8 bits (164), Expect = 3e-11
Identities = 61/231 (26%), Positives = 121/231 (52%), Gaps = 25/231 (10%)
Query: 240 MYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299
M + + +A A ++ + + + KK ER ++ E E++ Q+R +EAEER+
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI-EAEEKAAAQERERREAEERE 315
Query: 300 RAEERKQKELEELER-----ERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQL-- 352
R E +++ EE +R +R EE+ R +E+++R E R+ K+ EK AEE+++
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375
Query: 353 --QEKIKLEERK----LLLAQRNLQSIRLIAELLSRAKAVK-LREQEQKEEKLRL----Q 401
+EK K+EE+K L + +Q ++ E + + K + E++ +E+KL+ +
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 402 QQEERRRLQEAELRRVEEEKERALGLQ------RKERELRERLLSILLSKK 446
Q EE+ +A+ +++E+K + +K++E +E + S + KK
Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKK 486
Score = 65.1 bits (157), Expect = 2e-10
Identities = 44/175 (25%), Positives = 98/175 (56%), Gaps = 13/175 (7%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKE-----AEERQRAEERKQKELEELERERKREEKLR 323
K+ ERQ+++E E++ E+++R KE AEERQR +E +++ EE +R R EE+
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Query: 324 KREQKQRDRELRRNQKKLE--KLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLS 381
K E+++R+++L + ++ K++ E+ +Q E + E+K + LQ+ L +
Sbjct: 382 KVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK--AQEDKLQTAVLKKQGEE 439
Query: 382 RAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
+ V+ + ++ +E+K +++E +++ ++++ +E KE +++ E
Sbjct: 440 KGTKVQAKREKLQEDKPTFKKEE----IKDEKIKKDKEPKEEVKSFMDRKKGFTE 490
Score = 59.7 bits (143), Expect = 9e-09
Identities = 95/445 (21%), Positives = 182/445 (40%), Gaps = 63/445 (14%)
Query: 267 SIKKRQLERQKLQELEQQREEQ-----KRREKEAEERQRAEERKQ--------KELEELE 313
SI + Q+E ++ + +EE K + +EE ++ EER+Q +++EE +
Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 314 RERKREEKLRKREQKQRDRELRRNQKKL----EKLQAEEQKQLQEKIKLE----ERKLLL 365
+ER E+ R E ++R+R KK+ +++AEE+ QE+ + E ER
Sbjct: 262 KERAEAERAR-LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREE 320
Query: 366 AQRNLQSIRLIAELLSRA----KAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEK 421
+R + + I E RA + +K E+ EE+ R+ ++EE+R +E + R EEE+
Sbjct: 321 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI-KEEEKRAAEERQRARAEEEE 379
Query: 422 ERALGLQRKERELRERLLSILLSKKPDDSHTHDELG------VAHADLLQPVLDILQTVS 475
+ + Q++ ++L E+ ++ +K + G A D LQ + Q
Sbjct: 380 KAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEE 439
Query: 476 SGCVSATTLHPLGGQPPAGAPKE-SPAHPEADGAPK-SVNGSVAEEAPCKEVQSS----- 528
G L P +E + D PK V + + EV+S
Sbjct: 440 KGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM 499
Query: 529 CRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRG 588
+ + R PGG S + ++ +G P E ++ R +
Sbjct: 500 THKLKHTENTFSR-PGGRASV---DTKEAEGAPQVEAGKRLEELRRRR------------ 543
Query: 589 RATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRR 648
G + + E+ + ++ + + K++R ++ +++ RR+ D R R
Sbjct: 544 -----GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEAD--RKLR 596
Query: 649 SHSKDRHRRERSRERRGSASRKHSR 673
+ R +E RR A+ K +
Sbjct: 597 EEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/209 (18%), Positives = 102/209 (48%), Gaps = 19/209 (9%)
Query: 271 RQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKRE----------- 319
+ ++ ++ E+ ++E K +E+E EE+ + + ++E + E+ E
Sbjct: 170 KSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLK 229
Query: 320 ------EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSI 373
E+ ++ E++++ + + +K+E+ E + + +++ EER+ + A+++ +
Sbjct: 230 NGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIA 289
Query: 374 RLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERE 433
A + + KA + ++ E+ ++EE+R +E + R++EE++RA +++ +E
Sbjct: 290 DERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQ--RIKEEEKRAAEERQRIKE 347
Query: 434 LRERLLSILLSKKPDDSHTHDELGVAHAD 462
+R K ++ +E A A+
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAE 376
Score = 54.3 bits (129), Expect = 4e-07
Identities = 87/431 (20%), Positives = 161/431 (37%), Gaps = 67/431 (15%)
Query: 278 LQELEQQRE--EQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELR 335
+ + E++RE QKR E E + A +R + EE RER+R + + QKQ + L
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 336 RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKE 395
+ ++E Q + EE K ++ A L
Sbjct: 61 QVTDQVEV-------NAQNSVPDEEAKTTTTNTQVEGDDEAAFL---------------- 97
Query: 396 EKLRLQQQEERRRLQEAELRRVEEEKERA-LGLQRKERELRERLLSILLSKKPDDSHTHD 454
E+L +++ ++RLQEA R+ E + L R ++ ++K + S +
Sbjct: 98 ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ 157
Query: 455 ELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNG 514
E + ++ +TV T + A K+ E + K G
Sbjct: 158 E---------RYEIEETETV-------TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 515 SVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPD--NNQQPKGIPACEQN---VSR 569
S+ E + V+ E+ + E + V+S ++++PK EQ +S
Sbjct: 202 SIGE--------NQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISH 253
Query: 570 KDTRSEQDKCNREPSKGRGRATGDGLADRHKRERS------RARRASSREDGRPRKERRP 623
+ E+DK E + R A +R K E+ RAR + + +ERR
Sbjct: 254 HEKMEEEDKERAEAERARLEAEE---RERIKAEQDKKIADERARIEAEEKAAAQERERRE 310
Query: 624 HKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASR---KHSRHRRRSER 680
++ + +R + + + + +R + E+R + R K R ER
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 681 SRSRSPSRHRS 691
R+R+ ++
Sbjct: 371 QRARAEEEEKA 381
Score = 52.8 bits (125), Expect = 1e-06
Identities = 42/199 (21%), Positives = 98/199 (49%), Gaps = 25/199 (12%)
Query: 265 DASIKKRQLERQKLQELEQQREEQKRR-EKEAEERQRAEERKQKELEELERERKREEKLR 323
+ I+ + + +K QE + Q K++ E++ + Q E+ Q++ ++E ++EK++
Sbjct: 410 EQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK 469
Query: 324 K-REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKL------------------- 363
K +E K+ + +K +++++ + + K+K E
Sbjct: 470 KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 529
Query: 364 LLAQRNLQSIRLIAELLSRAKAVKLREQEQKE----EKLRLQQQEERRRLQEAELRRVEE 419
+ A + L+ +R + KL++++Q+ E+L+ +++E R+ L+E E RR +E
Sbjct: 530 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
Query: 420 EKERALGLQRKERELRERL 438
E +R L + ++R L+E +
Sbjct: 590 EADRKLREEEEKRRLKEEI 608
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/436 (15%), Positives = 161/436 (36%), Gaps = 54/436 (12%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRK---- 324
++R+L RQK +E+ + E + + +E + A ER+++ +E R+++ EE L +
Sbjct: 6 RRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQ 65
Query: 325 ----REQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIR------ 374
+ D E + + +E L+ + EER+ Q L+ +
Sbjct: 66 VEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTI 125
Query: 375 --LIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKER 432
L SR E E E++ + + ++ER ++E E +K + ++
Sbjct: 126 TDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK 185
Query: 433 ELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPP 492
E +E+ ++ ++ +G +++ + + + + GQ
Sbjct: 186 EDKEK------EEEEEEKPKRGSIGENQVEVM-----VEEKTTESQEETVVMSLKNGQIS 234
Query: 493 AGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPD 552
+ PK+ E S + + EE + R+ E+ K
Sbjct: 235 SEEPKQEEER-EQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKA----------- 282
Query: 553 NNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSR 612
+Q K I + ++ + Q++ RE A+ +R R +RA+
Sbjct: 283 --EQDKKIADERARIEAEEKAAAQERERRE-------------AEERERMREEEKRAAEE 327
Query: 613 EDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHS 672
+E+R ++ + +R + + + + +R R+ E + +
Sbjct: 328 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387
Query: 673 RHRRRSERSRSRSPSR 688
R+++ E+ + ++
Sbjct: 388 RNKQLEEKKHAMQETK 403
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/193 (23%), Positives = 97/193 (50%), Gaps = 11/193 (5%)
Query: 270 KRQLERQKLQE------LEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLR 323
K Q +R+KLQE E+ ++E+ +++KE +E ++ ++K E+ + + E
Sbjct: 443 KVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV-KSQNGEFMTH 501
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRA 383
K + + + ++ +AE Q++ +LEE + + + + + A
Sbjct: 502 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 561
Query: 384 KAVKLREQEQK-EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSIL 442
A++L E ++K EE+ ++ ++EE+RR QE R++ EE+E+ ++E E R +
Sbjct: 562 -ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKR--RLKEEIERRRAEAAEK 618
Query: 443 LSKKPDDSHTHDE 455
K P+D + D+
Sbjct: 619 RQKMPEDGLSDDK 631
Score = 50.8 bits (120), Expect = 4e-06
Identities = 45/202 (22%), Positives = 97/202 (48%), Gaps = 25/202 (12%)
Query: 257 FDSTKHLSDASI----KKRQLERQKLQELEQQREEQKRREK-EAEERQRAEERKQKELEE 311
FD T ++DAS+ ++ Q + + + E++ + + R+E+ E EE + + QK
Sbjct: 121 FDPT--ITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWR 178
Query: 312 LERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKI--------------- 356
E K+E+K ++ E++++ + + ++E + E+ + QE+
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 357 KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRR 416
K EE + + ++ E RA+A + R + ++ E+++ +Q +++ + R
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD---KKIADERARI 295
Query: 417 VEEEKERALGLQRKERELRERL 438
EEK A +R+E E RER+
Sbjct: 296 EAEEKAAAQERERREAEERERM 317
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/105 (25%), Positives = 61/105 (58%), Gaps = 3/105 (2%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERK 317
++ K L + ++ + E ++ ++L+Q+++E E EE ++ E ++K LEE E+ RK
Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAAL---ELEELKKKREERRKVLEEEEQRRK 587
Query: 318 REEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
+EE RK +++ R L+ ++ AE+++++ E +++K
Sbjct: 588 QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/105 (28%), Positives = 63/105 (60%), Gaps = 5/105 (4%)
Query: 266 ASIKKRQLERQKLQELEQQREEQKRR--EKEAEERQRAEERKQKELEELERERKREEKLR 323
AS+ ++ E E ++ EE +RR E E+EE ++ ++++Q+ ELE +K+ E+ R
Sbjct: 517 ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERR 576
Query: 324 KREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQR 368
K +++ E RR Q++ ++ EE+++ + K ++E R+ A++
Sbjct: 577 KVLEEE---EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 76.3 bits (186), Expect = 9e-14
Identities = 110/493 (22%), Positives = 201/493 (40%), Gaps = 87/493 (17%)
Query: 253 IKVSFDSTKHLSDASIKKRQLERQKLQELEQQ--REEQKRREKEAEERQRAEERKQKELE 310
+++S S + S S +K + +K ++ E++ R Q R K +E Q AEE + +E
Sbjct: 196 LELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETP 255
Query: 311 E------LERERKREEKLRKREQKQRD-------------------RELRRNQKKLEKLQ 345
+R K EE+ + E+++ D +E + +++ +++
Sbjct: 256 SRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVK 315
Query: 346 AEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEE 405
EE + K + +E+++L +R + R E K+ R+Q++KE K +EE
Sbjct: 316 PEEMMDERPKTRSQEQEVL--ERGGRFTRSQEE---ARKSHLARQQQEKEMKTTSPLEEE 370
Query: 406 RRRLQEAE-----------LRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHD 454
R ++ ++ R E+ K+ +L ++ E LL+K+ H
Sbjct: 371 EREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHP 430
Query: 455 ELGVAHAD--------LLQPVLDILQTVSSGC------VSATTLHPLGGQPPAGAPKESP 500
+L H++ PVL L ++ VS T+ +GG P +P ++
Sbjct: 431 QL---HSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTK 487
Query: 501 AHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGI 560
A A+ P+ + +++ + + + PE D + QP +
Sbjct: 488 AESPAEKVPEESVLPLVQKSTLADYSAQKDLEPES----------------DRSAQPLPL 531
Query: 561 PACEQNVSRKDTRSEQDKCNREPS--KGRGRATGDGLADRHKRERSRARRASSREDGRPR 618
E +++ T ++C ++PS + GR L H+ ++S A +SSR
Sbjct: 532 KIEELALAKGIT----EECLKQPSLEQKEGRRASHTLLPSHRLKQS-ADSSSSRSSSSSS 586
Query: 619 KERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRS 678
R + DS RS SP ++ R H R R + GS S SR R RS
Sbjct: 587 SSSRSRSR---SPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRS 643
Query: 679 ERSRSRSPSRHRS 691
RSRS S + +S
Sbjct: 644 -RSRSASSNSRKS 655
Score = 63.5 bits (153), Expect = 6e-10
Identities = 45/171 (26%), Positives = 81/171 (47%), Gaps = 11/171 (6%)
Query: 274 ERQKLQELEQQR---EEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQR 330
+ + ++ EQ+R E+ RE+E E R+R ++ + +++ + + R R +K+R
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKER 1188
Query: 331 DRELRRNQKKLEKLQAEEQKQLQE----KIKLEERKLLLAQRNLQSIRLIAELLSRAKAV 386
+ + +K EK Q E +L + K K L + Q ++ AE RAK
Sbjct: 1189 AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKER 1248
Query: 387 KLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ R +EQ+EE +Q+E + + R++E EK R +R RER
Sbjct: 1249 EKRRKEQEEE----EQKEREKEAERERNRQLEREKRREHSRERDRERERER 1295
Score = 57.0 bits (136), Expect = 6e-08
Identities = 36/95 (37%), Positives = 59/95 (62%), Gaps = 3/95 (3%)
Query: 258 DSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAE-ERQRAEERKQKELEELERER 316
DS +A +R ER+K ++ EQ+ EEQK REKEAE ER R ER+++ ER+R
Sbjct: 1231 DSQIVQKEAERAERAKEREKRRK-EQEEEEQKEREKEAERERNRQLEREKRREHSRERDR 1289
Query: 317 KREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQ 351
+RE + R+R++ RDR+ R++++ + + K+
Sbjct: 1290 ERERE-RERDRGDRDRDRERDRERGRERDRRDTKR 1323
Score = 52.4 bits (124), Expect = 1e-06
Identities = 23/93 (24%), Positives = 60/93 (64%), Gaps = 3/93 (3%)
Query: 263 LSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKL 322
L+D+ I +++ ER E ++RE++++ ++E E+++R +E +++ +LERE++RE
Sbjct: 1229 LTDSQIVQKEAERA---ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSR 1285
Query: 323 RKREQKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
+ +++R+RE R + ++ + E+ + +++
Sbjct: 1286 ERDRERERERERDRGDRDRDRERDRERGRERDR 1318
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/220 (25%), Positives = 86/220 (39%), Gaps = 23/220 (10%)
Query: 491 PPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCI 550
PP P + P HP A+ + +V E+ +E + R E E+ +
Sbjct: 1119 PPPPPPVQPPQHPRAE--QREQERAVREQWAEREREMERR---ERTRSEREWDRDKVREG 1173
Query: 551 PDNNQQPKGIPACEQNVSRKDTRSEQDKCNREP-----------SKGRGRATGDGLADRH 599
P + + + E+ S++ +++K EP +K L D
Sbjct: 1174 PRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQ 1233
Query: 600 --KRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHR- 656
++E RA RA RE R +E K+ + + R R + RR HS++R R
Sbjct: 1234 IVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLERE---KRREHSRERDRE 1290
Query: 657 RERSRER-RGSASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
RER RER RG R R R R R RH + +R
Sbjct: 1291 RERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSR 1330
Score = 50.8 bits (120), Expect = 4e-06
Identities = 41/173 (23%), Positives = 78/173 (45%), Gaps = 19/173 (10%)
Query: 283 QQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLE 342
+QRE+++ ++ ER+R ER+++ E E +R + + + + RDR + K E
Sbjct: 1134 EQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKE 1193
Query: 343 KLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQ 402
K +++K +E +L+ +L + KA + +Q+
Sbjct: 1194 KKSEKKEKAQEEP----------------PAKLLDDLFRKTKAAPCIYWLPLTDSQIVQK 1237
Query: 403 QEER-RRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHD 454
+ ER R +E E RR E+E+E +R++ RER + K+ + S D
Sbjct: 1238 EAERAERAKEREKRRKEQEEEEQK--EREKEAERERNRQLEREKRREHSRERD 1288
Score = 47.4 bits (111), Expect = 5e-05
Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 20/173 (11%)
Query: 518 EEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQD 577
E A KE +S + ++ P K + D ++ K P C + D++ Q
Sbjct: 1187 ERAKSKEKKSEKKEKAQEEPPAK--------LLDDLFRKTKAAP-CIYWLPLTDSQIVQK 1237
Query: 578 KCNR-EPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRR 636
+ R E +K R + + + K A R +R+ ER ++H+ + D R
Sbjct: 1238 EAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQ-----LEREKRREHSRERDRERE 1292
Query: 637 RSTSPDHTRSRRSHSKDRHR-RERSRERRGSASRKHSRHRRRSERSRSRSPSR 688
R + R R +DR R RER RER +++HSR R RS R R R
Sbjct: 1293 R----ERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 7/73 (9%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAE----ERQRAEER-KQKELEELERERKREEKLR 323
+ RQLER+K +E RE + RE+E E +R R ER +++ E R+ KR + R
Sbjct: 1271 RNRQLEREKRRE--HSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSR 1328
Query: 324 KREQKQRDRELRR 336
R RDR RR
Sbjct: 1329 SRSTPVRDRGGRR 1341
Score = 40.4 bits (93), Expect = 0.006
Identities = 19/70 (27%), Positives = 45/70 (64%), Gaps = 2/70 (2%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAE-ERQRAEERKQKELEELERERKREEKLRKREQ 327
++++ ER++ ++LE+++ + RE++ E ER+R +R ++ + ER+R+R + +R+
Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD-RDRERDRERGRERDRRDT 1321
Query: 328 KQRDRELRRN 337
K+ R R+
Sbjct: 1322 KRHSRSRSRS 1331
Score = 36.6 bits (83), Expect = 0.081
Identities = 84/381 (22%), Positives = 138/381 (36%), Gaps = 52/381 (13%)
Query: 331 DRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLRE 390
D R +LE++ + K LQ +++ + K L QR L + L+ R K + E
Sbjct: 52 DPSTSRKMAELEEVTLDG-KPLQA-LRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLE 109
Query: 391 QEQKEEKLRLQQQEERR---RLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKP 447
QK Q + + + + EK++ L QR ERE RE S +
Sbjct: 110 NLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAES 169
Query: 448 DDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADG 507
+D H E GV A LL P D ++ +P + SP +
Sbjct: 170 EDEMIHPE-GV--ASLLPP--DFQSSLE--------------RPELELSRHSPRKSSSIS 210
Query: 508 APKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNV 567
K G +E P K + S RV ++ LS QP ++
Sbjct: 211 EEK---GDSDDEKPRKGERRSSRV--------RQARAAKLS----EGSQPAEEEEDQETP 255
Query: 568 SRK-DTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPH-K 625
SR R++++ E + D + E ++R A ++ + E P K
Sbjct: 256 SRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVK 315
Query: 626 KHAYKDDSPRRRSTSPD-------HTRSRRSHSKDRHRRERSRERRGSASRKHSRHRR-- 676
D+ P+ RS + TRS+ K R++ + + S R
Sbjct: 316 PEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIK 375
Query: 677 --RSERSRSRSPSRHRSTWNR 695
+ + +S+SPS R T +R
Sbjct: 376 SSQGLKEKSKSPSPPRLTEDR 396
Score = 30.8 bits (68), Expect = 4.4
Identities = 25/86 (29%), Positives = 29/86 (33%), Gaps = 2/86 (2%)
Query: 605 RARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERR 664
R + E G PR P PR + R+ R +R R RER
Sbjct: 1102 RPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQE--RAVREQWAEREREMERRERT 1159
Query: 665 GSASRKHSRHRRRSERSRSRSPSRHR 690
S R RSRSRS R R
Sbjct: 1160 RSEREWDRDKVREGPRSRSRSRDRRR 1185
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 75.9 bits (185), Expect = 1e-13
Identities = 94/407 (23%), Positives = 175/407 (42%), Gaps = 76/407 (18%)
Query: 267 SIKKRQLERQKLQELEQQRE-EQKRREKEAEERQRAEERKQKELEELERERKREEKLRKR 325
S ++ +++R++LQE ++Q+E E++R E+E ER+R E R++ E E LERER +E+L +R
Sbjct: 136 SQEELEIQRRQLQEQQRQKELERERLERERMERERLE-RERLERERLERERLEQEQL-ER 193
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+++R+R+ E+L+ +E+ + QE+++ +ER L R +
Sbjct: 194 ERQERERQ--------ERLERQERLERQERLERQER------------------LDRER- 226
Query: 386 VKLREQEQKEEKLRLQ-QQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSIL-- 442
+E++++E RL+ +++ER R ++ E ++E E+ER + + L S+L
Sbjct: 227 ---QERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGD 283
Query: 443 -------LSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGA 495
L + T + G+ L P L G A+ P PP G
Sbjct: 284 SSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPL---PPGPAQASVALP----PPPGP 336
Query: 496 PKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQ 555
P P P P + + P P +P G L+ + ++N+
Sbjct: 337 PPPPPL-PSTGPPPPPPPPPLPNQVPPPP--------PPPPAPPLPASGFFLASMSEDNR 387
Query: 556 QPKGIPACEQNVS-RKDTRSEQ------------DKCNREPSKGRGRAT----GDGLADR 598
G+ A RK +R E + + + GRG G GL +
Sbjct: 388 PLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEE 447
Query: 599 HKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTR 645
+R RR + + +++ + + S +++P+ TR
Sbjct: 448 MSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTR 494
Score = 47.4 bits (111), Expect = 5e-05
Identities = 26/79 (32%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
Query: 261 KHLSDASIKKRQLERQKLQELEQQR--EEQKRREK-EAEERQRAEERKQKELEELERERK 317
+ L +++ + ER++ + LE+Q E Q+R E+ E +R+R E ++++ LE LERER+
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQ 243
Query: 318 REEKLRKREQKQRDRELRR 336
E+ + E++Q + E R
Sbjct: 244 ERERQEQLEREQLEWERER 262
Score = 34.7 bits (78), Expect = 0.31
Identities = 33/150 (22%), Positives = 55/150 (36%), Gaps = 13/150 (8%)
Query: 550 IPDNNQQPKGIPACEQNVSRKDT----RSEQDKCNREPSKGRGRATGDGLADRHKRERSR 605
+P N Q +PA QN ++ R + + R+ R R + + +R + ER R
Sbjct: 120 LPRQNSQ---LPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERM-ERERLERER 175
Query: 606 ARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRG 665
R + +++ ++ + + R+ R R DR R+ER
Sbjct: 176 LERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQER--- 232
Query: 666 SASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
R R R ER R R + W R
Sbjct: 233 --ERLERLERERQERERQEQLEREQLEWER 260
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 75.9 bits (185), Expect = 1e-13
Identities = 94/407 (23%), Positives = 175/407 (42%), Gaps = 76/407 (18%)
Query: 267 SIKKRQLERQKLQELEQQRE-EQKRREKEAEERQRAEERKQKELEELERERKREEKLRKR 325
S ++ +++R++LQE ++Q+E E++R E+E ER+R E R++ E E LERER +E+L +R
Sbjct: 136 SQEELEIQRRQLQEQQRQKELERERLERERMERERLE-RERLERERLERERLEQEQL-ER 193
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+++R+R+ E+L+ +E+ + QE+++ +ER L R +
Sbjct: 194 ERQERERQ--------ERLERQERLERQERLERQER------------------LDRER- 226
Query: 386 VKLREQEQKEEKLRLQ-QQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSIL-- 442
+E++++E RL+ +++ER R ++ E ++E E+ER + + L S+L
Sbjct: 227 ---QERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGD 283
Query: 443 -------LSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGA 495
L + T + G+ L P L G A+ P PP G
Sbjct: 284 SSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPL---PPGPAQASVALP----PPPGP 336
Query: 496 PKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQ 555
P P P P + + P P +P G L+ + ++N+
Sbjct: 337 PPPPPL-PSTGPPPPPPPPPLPNQVPPPP--------PPPPAPPLPASGFFLASMSEDNR 387
Query: 556 QPKGIPACEQNVS-RKDTRSEQ------------DKCNREPSKGRGRAT----GDGLADR 598
G+ A RK +R E + + + GRG G GL +
Sbjct: 388 PLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEE 447
Query: 599 HKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTR 645
+R RR + + +++ + + S +++P+ TR
Sbjct: 448 MSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTR 494
Score = 47.4 bits (111), Expect = 5e-05
Identities = 26/79 (32%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
Query: 261 KHLSDASIKKRQLERQKLQELEQQR--EEQKRREK-EAEERQRAEERKQKELEELERERK 317
+ L +++ + ER++ + LE+Q E Q+R E+ E +R+R E ++++ LE LERER+
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQ 243
Query: 318 REEKLRKREQKQRDRELRR 336
E+ + E++Q + E R
Sbjct: 244 ERERQEQLEREQLEWERER 262
Score = 34.7 bits (78), Expect = 0.31
Identities = 33/150 (22%), Positives = 55/150 (36%), Gaps = 13/150 (8%)
Query: 550 IPDNNQQPKGIPACEQNVSRKDT----RSEQDKCNREPSKGRGRATGDGLADRHKRERSR 605
+P N Q +PA QN ++ R + + R+ R R + + +R + ER R
Sbjct: 120 LPRQNSQ---LPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERM-ERERLERER 175
Query: 606 ARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRG 665
R + +++ ++ + + R+ R R DR R+ER
Sbjct: 176 LERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQER--- 232
Query: 666 SASRKHSRHRRRSERSRSRSPSRHRSTWNR 695
R R R ER R R + W R
Sbjct: 233 --ERLERLERERQERERQEQLEREQLEWER 260
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 75.9 bits (185), Expect = 1e-13
Identities = 65/192 (33%), Positives = 117/192 (60%), Gaps = 26/192 (13%)
Query: 269 KKRQLERQKLQELEQQ--REEQKRREKE--AEERQRAEERKQKELEELERER-----KRE 319
+K + + +K+QE E++ R+E+K RE+E +E+ +E+K +E +E RE+ ++E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 320 EKLRKREQKQRDRE--LRRNQKKL----EKLQAEEQK--QLQEKIKLEERKLLLAQRNLQ 371
EK+R+ E+ +D+E LR ++K+ EK+Q +E+K + +EKI+ +E K ++ L+
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 372 SIRLIAELLSR--AKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEE-KERALG 426
I E + + K+ EQE+K E++ ++Q+QEE+ R QE L + EE+ +E+ +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 427 LQRKERELRERL 438
LQ EL ERL
Sbjct: 554 LQ----ELEERL 561
Score = 73.2 bits (178), Expect = 8e-13
Identities = 58/199 (29%), Positives = 108/199 (54%), Gaps = 32/199 (16%)
Query: 263 LSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER-----K 317
L+ +K + +K+QE E++ EQ+ + +E EE+ +E K E EE RE+ +
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 318 REEKLRKREQKQRDRELRRNQKKLEKLQAEEQK---------QLQEKIKLEERKLLLAQR 368
+EEK+R++E+K R++E EK+ +E+K + +E++ +E K+ +
Sbjct: 351 QEEKIREQEEKIREQE--------EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 369 NLQSIRLIAELLSRAKAVKLREQEQ----KEEKLR-----LQQQEERRRLQEAELRRVEE 419
Q E R + K+REQE+ +EEK+R +Q QEE+ R E +++ EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 420 E-KERALGLQRKERELRER 437
+ +E+ +QR+E +++E+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQ 481
Score = 72.8 bits (177), Expect = 1e-12
Identities = 47/171 (27%), Positives = 104/171 (60%), Gaps = 14/171 (8%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
+ Q E+ + QE + R+E+K RE++ + +++ EE ++E + E+E KR+EK+ ++E+K
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 330 RDRELRRNQKKLEKLQAEEQ-KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
R+++ + +++ E + EE+ ++L+E ++ +E KL + +Q + K+
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE-----------EEEKM 464
Query: 389 REQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+EQE+K ++ ++Q+QEE+ QE L++ E+ E+ + R+E ++ E+
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQ 515
Score = 71.6 bits (174), Expect = 2e-12
Identities = 52/180 (28%), Positives = 109/180 (60%), Gaps = 17/180 (9%)
Query: 262 HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKE-LEELERER-KRE 319
H + I++++ + + +E +++EE+ R ++E RQ + R+Q E ++E E E ++E
Sbjct: 335 HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAEL 379
EK+R++E+K++++ R+ +K E+ EKI+ +E ++ R + IR + E+
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQ---------DEKIREQEEEM---WRQEEKIRELEEM 442
Query: 380 LSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ + + KLRE E+K EE+ ++Q+QEE+ + QE +++ EE+ R L ++E ++ E+
Sbjct: 443 M-QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Score = 70.5 bits (171), Expect = 5e-12
Identities = 46/150 (30%), Positives = 96/150 (64%), Gaps = 20/150 (13%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ-RDR 332
+ +K++ELE+ ++Q+ + +E EE+ + EE K +E EE + +++EEK++++E+K R
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE--KIQRQEEKIQEQEEKTWRQE 489
Query: 333 ELRRNQKKL----EKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
+L + ++K+ EK+ +E+K +++ K++E++ + ++ E R + V+L
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ---------EEKMREQEVRL 540
Query: 389 REQEQK--EEKLRLQQQEER--RRLQEAEL 414
+QE+K E+++RLQ+ EER + Q+AEL
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Score = 66.6 bits (161), Expect = 7e-11
Identities = 53/181 (29%), Positives = 110/181 (60%), Gaps = 20/181 (11%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELER----ERKREEKLRKR 325
KR+LER +L L Q++ Q ++ +E Q + Q ++EE E +++EEK+ ++
Sbjct: 245 KRKLERAQL--LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+K +++E + +++L K++ +E+K +++ K+ E++ + ++ + R ++ R +
Sbjct: 303 EEKIQEQEEKMCEQEL-KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI--REQE 359
Query: 386 VKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEE-----EKERALGLQRKERELRE 436
K+REQE+K EEK+R +Q+E+ + QE E+ R EE E++R + R+E+++RE
Sbjct: 360 EKIREQEEKMWRQEEKIR--EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 437 R 437
+
Sbjct: 418 Q 418
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/182 (24%), Positives = 106/182 (58%), Gaps = 18/182 (9%)
Query: 261 KHLSDASIK-KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKRE 319
K L S K + Q+E +L L Q++E+K +E ++ +E+++K E+ + R++E
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE----EKIQEQEEKMCEQELKIREQE 324
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAEL 379
EK+ ++E+K ++E EK++ +E K +++ K+ E++ + ++ + R ++
Sbjct: 325 EKMWRQEEKMHEQE--------EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 380 LSRAKAVKLREQEQKEEKLRLQQQEERRR----LQEAELRRVEEE-KERALGLQRKEREL 434
+ + ++ +E+E ++ ++++QEE+R+ QE ++R +E+ +E+ + R+E ++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 435 RE 436
RE
Sbjct: 437 RE 438
Score = 60.8 bits (146), Expect = 4e-09
Identities = 50/183 (27%), Positives = 102/183 (55%), Gaps = 8/183 (4%)
Query: 234 LRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQ--KRR 291
+R ++ M + ++ K K+ + K +RQ E+ + QE + R+E+ K+
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
Query: 292 EKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQK- 350
EK E+ ++ +++K E+ E+ +++EEK++++E+K R++E+R Q++ EK+Q +E +
Sbjct: 496 EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-EKMQEQEVRL 554
Query: 351 -QLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
+L+E++ KL ++ LL +S L+ V+L+ QE + L+ QQ R
Sbjct: 555 QELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQE--AQSLQQQQDHYRGH 612
Query: 409 LQE 411
LQ+
Sbjct: 613 LQQ 615
Score = 53.9 bits (128), Expect = 5e-07
Identities = 45/159 (28%), Positives = 90/159 (56%), Gaps = 21/159 (13%)
Query: 286 EEQKRREKEAEERQRAEERKQKELE----ELERERKREEKLRKREQKQRDRELRRNQKKL 341
EE K + E +E+ R E ++ E++ +L+R+ +R + L ++Q Q + + R K+L
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEAD--RLGKEL 271
Query: 342 EKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQK--EEKLR 399
+ + A+ Q Q++E E LL Q+ + R + K++EQE+K E++L+
Sbjct: 272 QSVSAKLQAQVEEN---ELWNLLNQQQEEKMWR---------QEEKIQEQEEKMCEQELK 319
Query: 400 LQQQEERRRLQEAELRRVEEE-KERALGLQRKERELRER 437
+++QEE+ QE ++ EE+ +E+ + R+E ++RE+
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Score = 49.7 bits (117), Expect = 9e-06
Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 9/137 (6%)
Query: 305 KQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE-KIKLEERKL 363
K+++ LE R + E K+++ EL+ + +E ++E Q +++ K KLE +L
Sbjct: 197 KERDAPSLELYRNT---ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253
Query: 364 LLAQRNLQ--SIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEK 421
LL Q+ LQ + RL EL S + ++ + +E + L QQQEE+ QE +++E++
Sbjct: 254 LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE---EKIQEQE 310
Query: 422 ERALGLQRKERELRERL 438
E+ + K RE E++
Sbjct: 311 EKMCEQELKIREQEEKM 327
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 75.9 bits (185), Expect = 1e-13
Identities = 65/192 (33%), Positives = 117/192 (60%), Gaps = 26/192 (13%)
Query: 269 KKRQLERQKLQELEQQ--REEQKRREKE--AEERQRAEERKQKELEELERER-----KRE 319
+K + + +K+QE E++ R+E+K RE+E +E+ +E+K +E +E RE+ ++E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 320 EKLRKREQKQRDRE--LRRNQKKL----EKLQAEEQK--QLQEKIKLEERKLLLAQRNLQ 371
EK+R+ E+ +D+E LR ++K+ EK+Q +E+K + +EKI+ +E K ++ L+
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 372 SIRLIAELLSR--AKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEE-KERALG 426
I E + + K+ EQE+K E++ ++Q+QEE+ R QE L + EE+ +E+ +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 427 LQRKERELRERL 438
LQ EL ERL
Sbjct: 554 LQ----ELEERL 561
Score = 73.2 bits (178), Expect = 8e-13
Identities = 58/199 (29%), Positives = 108/199 (54%), Gaps = 32/199 (16%)
Query: 263 LSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER-----K 317
L+ +K + +K+QE E++ EQ+ + +E EE+ +E K E EE RE+ +
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 318 REEKLRKREQKQRDRELRRNQKKLEKLQAEEQK---------QLQEKIKLEERKLLLAQR 368
+EEK+R++E+K R++E EK+ +E+K + +E++ +E K+ +
Sbjct: 351 QEEKIREQEEKIREQE--------EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 369 NLQSIRLIAELLSRAKAVKLREQEQ----KEEKLR-----LQQQEERRRLQEAELRRVEE 419
Q E R + K+REQE+ +EEK+R +Q QEE+ R E +++ EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 420 E-KERALGLQRKERELRER 437
+ +E+ +QR+E +++E+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQ 481
Score = 72.8 bits (177), Expect = 1e-12
Identities = 47/171 (27%), Positives = 104/171 (60%), Gaps = 14/171 (8%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
+ Q E+ + QE + R+E+K RE++ + +++ EE ++E + E+E KR+EK+ ++E+K
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 330 RDRELRRNQKKLEKLQAEEQ-KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
R+++ + +++ E + EE+ ++L+E ++ +E KL + +Q + K+
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE-----------EEEKM 464
Query: 389 REQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+EQE+K ++ ++Q+QEE+ QE L++ E+ E+ + R+E ++ E+
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQ 515
Score = 71.6 bits (174), Expect = 2e-12
Identities = 52/180 (28%), Positives = 109/180 (60%), Gaps = 17/180 (9%)
Query: 262 HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKE-LEELERER-KRE 319
H + I++++ + + +E +++EE+ R ++E RQ + R+Q E ++E E E ++E
Sbjct: 335 HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAEL 379
EK+R++E+K++++ R+ +K E+ EKI+ +E ++ R + IR + E+
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQ---------DEKIREQEEEM---WRQEEKIRELEEM 442
Query: 380 LSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
+ + + KLRE E+K EE+ ++Q+QEE+ + QE +++ EE+ R L ++E ++ E+
Sbjct: 443 M-QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Score = 70.5 bits (171), Expect = 5e-12
Identities = 46/150 (30%), Positives = 96/150 (64%), Gaps = 20/150 (13%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ-RDR 332
+ +K++ELE+ ++Q+ + +E EE+ + EE K +E EE + +++EEK++++E+K R
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE--KIQRQEEKIQEQEEKTWRQE 489
Query: 333 ELRRNQKKL----EKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKL 388
+L + ++K+ EK+ +E+K +++ K++E++ + ++ E R + V+L
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ---------EEKMREQEVRL 540
Query: 389 REQEQK--EEKLRLQQQEER--RRLQEAEL 414
+QE+K E+++RLQ+ EER + Q+AEL
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Score = 66.6 bits (161), Expect = 7e-11
Identities = 53/181 (29%), Positives = 110/181 (60%), Gaps = 20/181 (11%)
Query: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELER----ERKREEKLRKR 325
KR+LER +L L Q++ Q ++ +E Q + Q ++EE E +++EEK+ ++
Sbjct: 245 KRKLERAQL--LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
E+K +++E + +++L K++ +E+K +++ K+ E++ + ++ + R ++ R +
Sbjct: 303 EEKIQEQEEKMCEQEL-KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI--REQE 359
Query: 386 VKLREQEQK----EEKLRLQQQEERRRLQEAELRRVEE-----EKERALGLQRKERELRE 436
K+REQE+K EEK+R +Q+E+ + QE E+ R EE E++R + R+E+++RE
Sbjct: 360 EKIREQEEKMWRQEEKIR--EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 437 R 437
+
Sbjct: 418 Q 418
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/182 (24%), Positives = 106/182 (58%), Gaps = 18/182 (9%)
Query: 261 KHLSDASIK-KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKRE 319
K L S K + Q+E +L L Q++E+K +E ++ +E+++K E+ + R++E
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE----EKIQEQEEKMCEQELKIREQE 324
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAEL 379
EK+ ++E+K ++E EK++ +E K +++ K+ E++ + ++ + R ++
Sbjct: 325 EKMWRQEEKMHEQE--------EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 380 LSRAKAVKLREQEQKEEKLRLQQQEERRR----LQEAELRRVEEE-KERALGLQRKEREL 434
+ + ++ +E+E ++ ++++QEE+R+ QE ++R +E+ +E+ + R+E ++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 435 RE 436
RE
Sbjct: 437 RE 438
Score = 60.8 bits (146), Expect = 4e-09
Identities = 50/183 (27%), Positives = 102/183 (55%), Gaps = 8/183 (4%)
Query: 234 LRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQ--KRR 291
+R ++ M + ++ K K+ + K +RQ E+ + QE + R+E+ K+
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
Query: 292 EKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQK- 350
EK E+ ++ +++K E+ E+ +++EEK++++E+K R++E+R Q++ EK+Q +E +
Sbjct: 496 EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-EKMQEQEVRL 554
Query: 351 -QLQEKI-KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRR 408
+L+E++ KL ++ LL +S L+ V+L+ QE + L+ QQ R
Sbjct: 555 QELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQE--AQSLQQQQDHYRGH 612
Query: 409 LQE 411
LQ+
Sbjct: 613 LQQ 615
Score = 54.3 bits (129), Expect = 4e-07
Identities = 53/182 (29%), Positives = 99/182 (54%), Gaps = 27/182 (14%)
Query: 268 IKKRQLERQKLQELEQQR-----EEQKRREKEAEERQRAEERKQKELE----ELERERKR 318
I+K ER L LE R EE K + E +E+ R E ++ E++ +L+R+ +R
Sbjct: 192 IEKLTKERDALS-LELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 319 EEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAE 378
+ L ++Q Q + + R K+L+ + A+ Q Q++E E LL Q+ + R
Sbjct: 251 AQLLLPQQQLQVEAD--RLGKELQSVSAKLQAQVEEN---ELWNLLNQQQEEKMWR---- 301
Query: 379 LLSRAKAVKLREQEQK--EEKLRLQQQEERRRLQEAELRRVEEE-KERALGLQRKERELR 435
+ K++EQE+K E++L++++QEE+ QE ++ EE+ +E+ + R+E ++R
Sbjct: 302 -----QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR 356
Query: 436 ER 437
E+
Sbjct: 357 EQ 358
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/139 (30%), Positives = 76/139 (54%), Gaps = 7/139 (5%)
Query: 303 ERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQE-KIKLEER 361
E+ KE + L E R + E K+++ EL+ + +E ++E Q +++ K KLE
Sbjct: 193 EKLTKERDALSLELYRNT-ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 362 KLLLAQRNLQ--SIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEE 419
+LLL Q+ LQ + RL EL S + ++ + +E + L QQQEE+ QE +++E
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE---EKIQE 308
Query: 420 EKERALGLQRKERELRERL 438
++E+ + K RE E++
Sbjct: 309 QEEKMCEQELKIREQEEKM 327
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 74.3 bits (181), Expect = 3e-13
Identities = 108/464 (23%), Positives = 192/464 (41%), Gaps = 87/464 (18%)
Query: 259 STKHLSDASIKKRQLERQKLQELEQQR----EEQKRREKEAEERQRAEERKQKELEELER 314
+ K S+A ++++QLE+Q+ + E +R E QKR E++ E+R+R EE++++E +EL +
Sbjct: 360 ANKERSEA-LRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRRE-KELRK 417
Query: 315 ERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIR 374
+++RE++ EQ +R+ E RR + EQ+ ++ +++ E+R+L + Q+ L +
Sbjct: 418 QQEREQRRHYEEQMRREEERRRAE--------HEQEYIRRQLEEEQRQLEILQQQLLHEQ 469
Query: 375 LIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKEREL 434
+ L E ++K+ L++Q + RLQ R++++E++ + LQ + +E
Sbjct: 470 AL-----------LLEYKRKQ----LEEQRQAERLQ----RQLKQERDYLVSLQHQRQEQ 510
Query: 435 RERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAG 494
R + KKP H + + + + L V S + T + QP G
Sbjct: 511 RP------VEKKP-LYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKG 563
Query: 495 APKESPA---------HPEADGAPKSVNGSV---------------AEEAPCKEVQSSCR 530
A P + P S N + E+ P K Q +
Sbjct: 564 LSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTS 623
Query: 531 VVPEDGSPEKRCPGGVLSCIPDNNQQP---------KGIPACEQNVSRKDTRSEQDKC-- 579
+ P K PG + P QP + P E + R + S
Sbjct: 624 ISP--ALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTP 681
Query: 580 NREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRST 639
+ +PS G G + ER+R RA+S+ +G P P K + R S
Sbjct: 682 SSQPSSQGGSQPG---SQAGSSERTRV-RANSKSEGSPVLPHEPAKVKPEESRDITRPSR 737
Query: 640 SPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRS 683
D T + + RE E +K + + SE S S
Sbjct: 738 PADLT------ALAKELRELRIEETNRPMKKVTDYSSSSEESES 775
Score = 57.8 bits (138), Expect = 3e-08
Identities = 53/180 (29%), Positives = 91/180 (50%), Gaps = 12/180 (6%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
I+ + ERQ +L+ + K++ E +E + ++E EE + E
Sbjct: 289 IRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGES 348
Query: 328 KQRDRELRRNQKKLEKLQAEEQKQL--QEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
R LR E+ +A ++QL Q++ E ++ LLA+R + I E + +
Sbjct: 349 TLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ----KRIEEQKEQRR- 403
Query: 386 VKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQ---RKERELRERLLSIL 442
+L EQ+++E++LR QQ+ E+RR E ++RR EEE+ RA Q R++ E +R L IL
Sbjct: 404 -RLEEQQRREKELRKQQEREQRRHYEEQMRR-EEERRRAEHEQEYIRRQLEEEQRQLEIL 461
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/169 (26%), Positives = 88/169 (52%), Gaps = 21/169 (12%)
Query: 282 EQQREEQKRREKEAEERQRAEERKQKELEELERERK-REEKLRKREQKQRDRELRRNQKK 340
E++ EE E + E +++ L+ K R E LR+++ +Q+ RE N++
Sbjct: 327 EEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRE---NEEH 383
Query: 341 LEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQK---EEK 397
+L AE QK+++E+ K + R+L QR + +R K +E+EQ+ EE+
Sbjct: 384 KRQLLAERQKRIEEQ-KEQRRRLEEQQRREKELR------------KQQEREQRRHYEEQ 430
Query: 398 LRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKK 446
+R +++ R ++ +RR EE++R L + +++ L E+ L + +K
Sbjct: 431 MRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQL-LHEQALLLEYKRK 478
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/149 (21%), Positives = 76/149 (51%), Gaps = 6/149 (4%)
Query: 293 KEAEERQRAEE-RKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQ 351
K +R E+ K + + ER+ +L+ + + + +++ + E +EE+++
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEE 331
Query: 352 LQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE 411
+ + L + L+ L +L ++ ++ LR Q+ +++ + + +E +R+L
Sbjct: 332 ENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQ--QRENEEHKRQLLA 389
Query: 412 AELRRVEEEKERALGL---QRKERELRER 437
+R+EE+KE+ L QR+E+ELR++
Sbjct: 390 ERQKRIEEQKEQRRRLEEQQRREKELRKQ 418
Score = 30.0 bits (66), Expect = 7.5
Identities = 25/129 (19%), Positives = 52/129 (40%), Gaps = 2/129 (1%)
Query: 552 DNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASS 611
+ + G P+ N+ + T + +K R A ++ +RE +R
Sbjct: 329 EEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL 388
Query: 612 REDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKH 671
E + R E + ++ ++ R + R +R H +++ RRE R RR +++
Sbjct: 389 AERQK-RIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER-RRAEHEQEY 446
Query: 672 SRHRRRSER 680
R + E+
Sbjct: 447 IRRQLEEEQ 455
>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
isoform 2 [Homo sapiens]
Length = 470
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/174 (28%), Positives = 99/174 (56%), Gaps = 10/174 (5%)
Query: 269 KKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEEL-ERERKREE---KLRK 324
+KR+ R++ E ++QREE++R+ KE E+R+R + K K+++ + ER++ ++E KL K
Sbjct: 213 EKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLK 272
Query: 325 REQKQRDREL--RRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSR 382
+ +K ++EL R KKL+K +++ + L +R + L+ +
Sbjct: 273 KPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKR----SDSELKDEKPKRPEDES 328
Query: 383 AKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
+ + RE+E + ++ R+ ++ ER + QE E RR +E E+ +RKE E+++
Sbjct: 329 GRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKK 382
Score = 45.8 bits (107), Expect = 1e-04
Identities = 48/200 (24%), Positives = 96/200 (48%), Gaps = 24/200 (12%)
Query: 274 ERQKLQELEQQREEQKRREKEAEERQRAEER-----KQKELEELERERKREEKLRKREQK 328
E+ +EL++ RE+ K+ +KE +RA + K+ + E + + KR E R+ +
Sbjct: 275 EKGDEKELDK-REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYR 333
Query: 329 QRDRELRRNQKKL----EKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAK 384
+R+RE R+Q+++ E+L+ +E+++ ++K + E+ K + + E + + K
Sbjct: 334 EREREYERDQERILRERERLKRQEEERRRQKERYEKEK---------TFKRKEEEMKKEK 384
Query: 385 AVKLREQEQKEEKLRLQQQEERRRLQEAELR--RVEEEKERALGLQRKERELRERLLSIL 442
LR++ +K E E+ +E ++ R+ + A+ L + R RL
Sbjct: 385 DT-LRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPD 443
Query: 443 LSKKPDDS--HTHDELGVAH 460
S K DS E G++H
Sbjct: 444 DSTKSGDSAAERKQESGISH 463
Score = 44.3 bits (103), Expect = 4e-04
Identities = 35/129 (27%), Positives = 69/129 (53%), Gaps = 6/129 (4%)
Query: 237 MKLMYKGEDG--KAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKE 294
+KL+ K E G K + K ++LSD + K + E + E+ KR E E
Sbjct: 268 IKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDE 327
Query: 295 AEERQRAEERK-QKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQ 353
+ R ER+ +++ E + RER E+L+++E+++R ++ R ++K K + EE K+ +
Sbjct: 328 SGRDYREREREYERDQERILRER---ERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEK 384
Query: 354 EKIKLEERK 362
+ ++ + +K
Sbjct: 385 DTLRDKGKK 393
Score = 44.3 bits (103), Expect = 4e-04
Identities = 37/143 (25%), Positives = 76/143 (53%), Gaps = 14/143 (9%)
Query: 265 DASIKKRQLERQKLQELEQQREE---QKRREKEA--EERQRAEERKQKELEELERERKRE 319
D K ++L+++ L + + KR + E E+ +R E+ ++ E ERE +R+
Sbjct: 283 DKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERD 342
Query: 320 EK--LRKREQKQRDRELRRNQKKLEKLQAEEQ-KQLQEKIKLEERKLLLAQRNLQSIRLI 376
++ LR+RE+ +R E RR QK E+ + E+ K+ +E++K E+ L + +S
Sbjct: 343 QERILRERERLKRQEEERRRQK--ERYEKEKTFKRKEEEMKKEKDTLRDKGKKAES---- 396
Query: 377 AELLSRAKAVKLREQEQKEEKLR 399
E + ++ + +E+ K +++R
Sbjct: 397 TESIGSSEKTEKKEEVVKRDRIR 419
Score = 39.7 bits (91), Expect = 0.010
Identities = 25/99 (25%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Query: 264 SDASIKKRQLERQKLQELEQQREEQK--RREKEAEERQRAEERKQKELEELERERKREEK 321
SD+ +K + +R + + RE ++ R++E R+R ++Q+E ++ER +EK
Sbjct: 312 SDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEK 371
Query: 322 LRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEE 360
KR++++ +E + K +K ++ E EK + +E
Sbjct: 372 TFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKE 410
Score = 39.3 bits (90), Expect = 0.012
Identities = 66/351 (18%), Positives = 135/351 (38%), Gaps = 25/351 (7%)
Query: 320 EKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAEL 379
+K K++ K+RD ++ E + E + + LL + ++ LIA+
Sbjct: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAK- 195
Query: 380 LSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLL 439
K L + ++++R +++EERRR + R+ EEE+ + ++++R+ E+L
Sbjct: 196 ----KTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLK 251
Query: 440 SILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKES 499
I + P+ DE P + +L+ G + +
Sbjct: 252 KI--DRIPERDKLKDE----------PKIKLLKKPEKGDEKELDKREKAKKLDKENLSDE 299
Query: 500 PAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGV------LSCIPDN 553
A ++ PK + + +E P + S R E +R + L +
Sbjct: 300 RASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEE 359
Query: 554 NQQPKGIPACEQNVSRKDTRSEQDKCN-REPSKGRGRATGDGLADRHKRERSRARRASSR 612
++ K E+ RK+ +++K R+ K G +++ +++ +R R
Sbjct: 360 RRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIR 419
Query: 613 EDGRPRKE-RRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRE 662
RP + +P + + P + S D R+ S HR+E E
Sbjct: 420 NKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
Score = 35.4 bits (80), Expect = 0.18
Identities = 19/78 (24%), Positives = 43/78 (55%)
Query: 268 IKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
+K+++ ER++ +E ++ + KR+E+E ++ + K K+ E E E+ +K E
Sbjct: 353 LKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEV 412
Query: 328 KQRDRELRRNQKKLEKLQ 345
+RDR +++ ++ Q
Sbjct: 413 VKRDRIRNKDRPAMQLYQ 430
Score = 33.5 bits (75), Expect = 0.68
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 8/128 (6%)
Query: 565 QNVSRKDTRSEQDKCNREPS-KGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRP 623
+ + + D E+DK EP K + + KRE+++ + D R +
Sbjct: 248 EKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCT 307
Query: 624 HKKHA---YKDDSPRR--RSTSPDHTRSRRSHSKDRHR--RERSRERRGSASRKHSRHRR 676
K + KD+ P+R + D+ R + +D+ R RER R +R R+ + R
Sbjct: 308 LPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERY 367
Query: 677 RSERSRSR 684
E++ R
Sbjct: 368 EKEKTFKR 375
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,134,353
Number of Sequences: 37866
Number of extensions: 1561496
Number of successful extensions: 69210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1408
Number of HSP's successfully gapped in prelim test: 1300
Number of HSP's that attempted gapping in prelim test: 11545
Number of HSP's gapped (non-prelim): 21097
length of query: 695
length of database: 18,247,518
effective HSP length: 109
effective length of query: 586
effective length of database: 14,120,124
effective search space: 8274392664
effective search space used: 8274392664
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.