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Search of human proteins with 40788018
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo
sapiens]
(501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo sa... 1001 0.0
gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sap... 986 0.0
gi|89886350 Rho GTPase activating protein 11B [Homo sapiens] 438 e-123
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 85 1e-16
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a... 85 1e-16
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b... 85 1e-16
gi|91208437 GEM interacting protein [Homo sapiens] 82 9e-16
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 82 1e-15
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 81 2e-15
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 81 2e-15
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 81 2e-15
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 81 2e-15
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 79 1e-14
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 79 1e-14
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 79 1e-14
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 79 1e-14
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 78 2e-14
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 77 3e-14
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 77 3e-14
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 75 2e-13
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 75 2e-13
gi|54860105 nadrin isoform 2 [Homo sapiens] 75 2e-13
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 75 2e-13
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 75 2e-13
gi|54860079 nadrin isoform 1 [Homo sapiens] 74 3e-13
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 74 4e-13
gi|56119110 family with sequence similarity 13, member A1 isofor... 71 2e-12
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 71 3e-12
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 71 3e-12
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 71 3e-12
>gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo
sapiens]
Length = 501
Score = 1001 bits (2588), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
Sbjct: 1 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
Query: 61 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
Sbjct: 61 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
Sbjct: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
Sbjct: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
Query: 241 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300
VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
Sbjct: 241 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300
Query: 301 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360
RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
Sbjct: 301 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360
Query: 361 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420
NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
Sbjct: 361 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420
Query: 421 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480
FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
Sbjct: 421 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480
Query: 481 LLFSPDVDEKLPKKGTFTYYC 501
LLFSPDVDEKLPKKGTFTYYC
Sbjct: 481 LLFSPDVDEKLPKKGTFTYYC 501
>gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo
sapiens]
Length = 1023
Score = 986 bits (2550), Expect = 0.0
Identities = 495/496 (99%), Positives = 496/496 (100%)
Query: 1 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
Sbjct: 1 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
Query: 61 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
Sbjct: 61 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
Sbjct: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
Sbjct: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
Query: 241 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300
VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
Sbjct: 241 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300
Query: 301 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360
RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
Sbjct: 301 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360
Query: 361 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420
NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
Sbjct: 361 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420
Query: 421 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480
FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
Sbjct: 421 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480
Query: 481 LLFSPDVDEKLPKKGT 496
LLFSPDVDEKLPKKG+
Sbjct: 481 LLFSPDVDEKLPKKGS 496
>gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]
Length = 267
Score = 438 bits (1126), Expect = e-123
Identities = 220/231 (95%), Positives = 222/231 (96%), Gaps = 5/231 (2%)
Query: 1 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
MWDQRLV+LALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
Sbjct: 1 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
Query: 61 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
EYGHIPSFLVDACTSLE+HIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
Sbjct: 61 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKA LLLSCLLADHTVHVLRYFFNFLRN
Sbjct: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN 180
Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTL 231
VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSN EKK V QTL
Sbjct: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTL 226
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 85.1 bits (209), Expect = 1e-16
Identities = 59/171 (34%), Positives = 84/171 (49%), Gaps = 7/171 (4%)
Query: 42 IGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALK 99
+GG IFG H + LV+ C E + EGLFR G ++ L+
Sbjct: 148 LGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQ 207
Query: 100 NKVDHGEGCL--SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATL 157
+ D GE L S+ +A LLK + RELPEP++P +E L QL T+++ + TL
Sbjct: 208 DSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTL 267
Query: 158 LLS---CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQ 205
L+ L ++LRY FL V S+ NKM NLA +F PN+L+
Sbjct: 268 ELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILR 318
>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
[Homo sapiens]
Length = 1071
Score = 85.1 bits (209), Expect = 1e-16
Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 5/152 (3%)
Query: 83 EGLFRKSGSVIRLKALKNKVDHGE----GCLSSAPPCDIAGLLKQFFRELPEPILPADL- 137
EG+FR SGS + + +KN + GE G + IAG+LK +FR L P+ P D+
Sbjct: 523 EGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIF 582
Query: 138 HEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAV 197
H+ + +E+ + +L T+ ++RY F FL ++S S EN MD NLA+
Sbjct: 583 HDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAI 642
Query: 198 IFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ 229
F P+L+ EGH+++S ++ ++Q
Sbjct: 643 CFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQ 674
>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
[Homo sapiens]
Length = 836
Score = 85.1 bits (209), Expect = 1e-16
Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 5/152 (3%)
Query: 83 EGLFRKSGSVIRLKALKNKVDHGE----GCLSSAPPCDIAGLLKQFFRELPEPILPADL- 137
EG+FR SGS + + +KN + GE G + IAG+LK +FR L P+ P D+
Sbjct: 523 EGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIF 582
Query: 138 HEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAV 197
H+ + +E+ + +L T+ ++RY F FL ++S S EN MD NLA+
Sbjct: 583 HDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAI 642
Query: 198 IFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ 229
F P+L+ EGH+++S ++ ++Q
Sbjct: 643 CFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQ 674
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 82.4 bits (202), Expect = 9e-16
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 25/189 (13%)
Query: 46 IFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH--IHTEGLFRKSGSVIRLKALKNKVD 103
+FGV F LP E +P F+V CT+ +H + +G++R SGS +R++ L +
Sbjct: 548 LFGVDFLQLPRDFPEE---VP-FVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE 603
Query: 104 HGEGC--LSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQL---------GTEE- 151
+G LS P D++ +LK+F +EL EP++P L++A + + GT
Sbjct: 604 NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSP 663
Query: 152 -----KNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQT 206
++ TLL+ L D + LR+ L V+ R ENKM ++NL ++F P LL+
Sbjct: 664 SPEVIRSLKTLLVQ--LPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP 721
Query: 207 SEGHEKMSS 215
+G S+
Sbjct: 722 PDGPRAASA 730
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 82.0 bits (201), Expect = 1e-15
Identities = 55/154 (35%), Positives = 81/154 (52%), Gaps = 9/154 (5%)
Query: 83 EGLFRKSGSVIRLKALKNKVDHGE-----GCLSSAPPCD-IAGLLKQFFRELPEPILPAD 136
EG+FR SG+ +R+ +++ + GE GC +A D +AG+LK +FR L P+ P D
Sbjct: 539 EGIFRVSGAQLRVSEIRDAFERGEDPLVEGC--TAHDLDSVAGVLKLYFRSLEPPLFPPD 596
Query: 137 LHEALLKAQQL-GTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNL 195
L LL + +L T E+ + L L + VLRY F FL +++ S EN MD NL
Sbjct: 597 LFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNL 656
Query: 196 AVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ 229
AV F P LL G + ++ +Q +VQ
Sbjct: 657 AVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQ 690
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 81.3 bits (199), Expect = 2e-15
Identities = 64/207 (30%), Positives = 99/207 (47%), Gaps = 23/207 (11%)
Query: 47 FGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHG 105
FGV L PE IP L + L+ H + TEG+FR+S + ++ ++ K + G
Sbjct: 242 FGVSLQHLQEKN-PEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG 300
Query: 106 EGCLSSAPPCDI---------AGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
P D A +LK F RELPEP+L DL+ ++ + ++ AT
Sbjct: 301 L-------PVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPAT 353
Query: 157 LLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSN 216
L + L + VLR+ FL +S S +NKM ++NLAV+F PNLL K ++
Sbjct: 354 LQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWA-----KDAAI 408
Query: 217 TEKKLRLQAAVVQTLIDYASDIGRVPD 243
T K + + L+D+ ++ PD
Sbjct: 409 TLKAINPINTFTKFLLDHQGELFPSPD 435
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 81.3 bits (199), Expect = 2e-15
Identities = 66/216 (30%), Positives = 100/216 (46%), Gaps = 19/216 (8%)
Query: 60 PEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPC--D 116
P Y +P + C LE H + T G+FR S R++ L+ + D G D
Sbjct: 202 PIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHD 261
Query: 117 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRY 173
+A LLK+F R++P+P+L +L+ A + L EE+ LL LL T+H L
Sbjct: 262 VAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 321
Query: 174 FFNFLR-----NVSLRSSE---NKMDSSNLAVIFAPNLLQTSEGHEK-----MSSNTEKK 220
F + + N+S E NKM S NLA IF PNLL + +K S+ E+
Sbjct: 322 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 381
Query: 221 LRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGID 256
+ A V + + +Y + PD E + ++L D
Sbjct: 382 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 417
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 81.3 bits (199), Expect = 2e-15
Identities = 66/216 (30%), Positives = 100/216 (46%), Gaps = 19/216 (8%)
Query: 60 PEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPC--D 116
P Y +P + C LE H + T G+FR S R++ L+ + D G D
Sbjct: 405 PIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHD 464
Query: 117 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRY 173
+A LLK+F R++P+P+L +L+ A + L EE+ LL LL T+H L
Sbjct: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 524
Query: 174 FFNFLR-----NVSLRSSE---NKMDSSNLAVIFAPNLLQTSEGHEK-----MSSNTEKK 220
F + + N+S E NKM S NLA IF PNLL + +K S+ E+
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
Query: 221 LRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGID 256
+ A V + + +Y + PD E + ++L D
Sbjct: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 81.3 bits (199), Expect = 2e-15
Identities = 66/216 (30%), Positives = 100/216 (46%), Gaps = 19/216 (8%)
Query: 60 PEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPC--D 116
P Y +P + C LE H + T G+FR S R++ L+ + D G D
Sbjct: 405 PIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHD 464
Query: 117 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRY 173
+A LLK+F R++P+P+L +L+ A + L EE+ LL LL T+H L
Sbjct: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 524
Query: 174 FFNFLR-----NVSLRSSE---NKMDSSNLAVIFAPNLLQTSEGHEK-----MSSNTEKK 220
F + + N+S E NKM S NLA IF PNLL + +K S+ E+
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
Query: 221 LRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGID 256
+ A V + + +Y + PD E + ++L D
Sbjct: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 79.0 bits (193), Expect = 1e-14
Identities = 56/177 (31%), Positives = 89/177 (50%), Gaps = 12/177 (6%)
Query: 67 SFLVDACTS--LEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLS-----SAPPCDIAG 119
+F ++AC + LE + EGLFR + S +LK LK +D C+ SA P IAG
Sbjct: 269 AFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC---CVVDVQEYSADPHAIAG 325
Query: 120 LLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVH-VLRYFFNFL 178
LK + RELPEP++ +L++ ++A + ++K L +C H +RY FL
Sbjct: 326 ALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFL 385
Query: 179 RNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYA 235
+S NKM SN+A++ PNLL T L++ +++ +I +A
Sbjct: 386 SKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI-VGIIEPIIQHA 441
>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 78.6 bits (192), Expect = 1e-14
Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 11/215 (5%)
Query: 45 KIFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKN 100
++FGVP ++L H +P +P L + LE + EG+ R GS R+K L+
Sbjct: 266 RLFGVPLDSLLEADHKVLPST-QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQ 324
Query: 101 KVDH----GEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
K++ G D + LLK+F R+LP P+L A+ A + ++
Sbjct: 325 KLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQV 384
Query: 157 L-LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
L LL +L + + L+ FLR V R NKM N++ + APNL K+
Sbjct: 385 LHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPK 444
Query: 216 NTEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
EK+L AA VVQ ++ Y + V F++ ++
Sbjct: 445 GKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQV 479
>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 78.6 bits (192), Expect = 1e-14
Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 11/215 (5%)
Query: 45 KIFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKN 100
++FGVP ++L H +P +P L + LE + EG+ R GS R+K L+
Sbjct: 266 RLFGVPLDSLLEADHKVLPST-QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQ 324
Query: 101 KVDH----GEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
K++ G D + LLK+F R+LP P+L A+ A + ++
Sbjct: 325 KLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQV 384
Query: 157 L-LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
L LL +L + + L+ FLR V R NKM N++ + APNL K+
Sbjct: 385 LHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPK 444
Query: 216 NTEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
EK+L AA VVQ ++ Y + V F++ ++
Sbjct: 445 GKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQV 479
>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
sapiens]
Length = 622
Score = 78.6 bits (192), Expect = 1e-14
Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 11/215 (5%)
Query: 45 KIFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKN 100
++FGVP ++L H +P +P L + LE + EG+ R GS R+K L+
Sbjct: 266 RLFGVPLDSLLEADHKVLPST-QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQ 324
Query: 101 KVDH----GEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
K++ G D + LLK+F R+LP P+L A+ A + ++
Sbjct: 325 KLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQV 384
Query: 157 L-LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
L LL +L + + L+ FLR V R NKM N++ + APNL K+
Sbjct: 385 LHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPK 444
Query: 216 NTEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
EK+L AA VVQ ++ Y + V F++ ++
Sbjct: 445 GKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQV 479
>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
Length = 663
Score = 77.8 bits (190), Expect = 2e-14
Identities = 67/214 (31%), Positives = 98/214 (45%), Gaps = 11/214 (5%)
Query: 46 IFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNK 101
+F VP AL VP IP + +E+ + TEGL R G+ IR+K L +
Sbjct: 321 LFCVPLTALLEQDQRKVPGM-RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQE 379
Query: 102 VD----HGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKN-KAT 156
++ G S D A LLK F RELP+P+L + +A Q L T+++ +A
Sbjct: 380 LEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439
Query: 157 LLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSN 216
LL LL D L+ FL+ V +NKM N+A++ APNL K S
Sbjct: 440 NLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQ 499
Query: 217 TEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
E + A + LI Y + +P FI+ ++
Sbjct: 500 REFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQV 533
>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
Length = 1528
Score = 77.4 bits (189), Expect = 3e-14
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 9/175 (5%)
Query: 46 IFGVPFNA-LPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVD 103
+FGVP + + P +P + A L +H + GLFRKSG R++AL+ +
Sbjct: 1075 VFGVPLTVNVQRTGQP----LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNE 1130
Query: 104 HGEGCLS--SAPPCDIAGLLKQFFRELPEPILPADLHEALLKA-QQLGTEEKNKATLLLS 160
C++ D+A +LKQ+FR+LPEP++ L E L+ Q + +++ +A
Sbjct: 1131 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 1190
Query: 161 CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
LL D VL+ FL +V+ EN+M +NLAV AP+L + + SS
Sbjct: 1191 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSS 1245
>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
Length = 1091
Score = 77.4 bits (189), Expect = 3e-14
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 9/175 (5%)
Query: 46 IFGVPFNA-LPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVD 103
+FGVP + + P +P + A L +H + GLFRKSG R++AL+ +
Sbjct: 638 VFGVPLTVNVQRTGQP----LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNE 693
Query: 104 HGEGCLS--SAPPCDIAGLLKQFFRELPEPILPADLHEALLKA-QQLGTEEKNKATLLLS 160
C++ D+A +LKQ+FR+LPEP++ L E L+ Q + +++ +A
Sbjct: 694 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 753
Query: 161 CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
LL D VL+ FL +V+ EN+M +NLAV AP+L + + SS
Sbjct: 754 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSS 808
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 74.7 bits (182), Expect = 2e-13
Identities = 60/183 (32%), Positives = 90/183 (49%), Gaps = 10/183 (5%)
Query: 65 IPSFLVDACTSL-EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDI---AGL 120
IP L T L E + TEGLFR+S SV ++ ++ + G+ ++ DI A +
Sbjct: 331 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP-VNFDDYGDIHIPAVI 389
Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
LK F RELP+P+L +E +L + + + + L +H VLRY FL
Sbjct: 390 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHA 449
Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
VS S NKM+SSNLA +F NL+ S+G +S+ + + LI+Y I
Sbjct: 450 VSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNM-----FTELLIEYYEKIFS 504
Query: 241 VPD 243
P+
Sbjct: 505 TPE 507
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 74.7 bits (182), Expect = 2e-13
Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 7/171 (4%)
Query: 51 FNALPHSAVPEYGHIPSFLVDACTSLED--HIHTEGLFRKSGSVIRLKALKNKVDHGEGC 108
FN + V + G + +V++C + + +G+FR SGS + + +KN + GE
Sbjct: 504 FNGDLETFVKDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENP 563
Query: 109 L----SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGT-EEKNKATLLLSCLL 163
L S+ +AG+LK +FR L P+ P + L+ ++ E+ L L
Sbjct: 564 LADDQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALHIRKLLLTL 623
Query: 164 ADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMS 214
+ V+RY F FL ++S S EN MD NLA+ F P L+ E +++S
Sbjct: 624 PRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVS 674
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 74.7 bits (182), Expect = 2e-13
Identities = 68/239 (28%), Positives = 105/239 (43%), Gaps = 18/239 (7%)
Query: 70 VDACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSS--APPCDIAGLLKQFF 125
++AC L E + EGLFR +LK LK +D L + P +AG LK +
Sbjct: 269 IEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYL 328
Query: 126 RELPEPILPADLHEALLKAQQLGTEEKNKATLLLSC-LLADHTVHVLRYFFNFLRNVSLR 184
RELPEP++ +L+E + + ++K L +C L RY FL ++
Sbjct: 329 RELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQT 388
Query: 185 SSENKMDSSNLAVIFAPNLL-QTSEGH-EKMSSNTEKKLRLQAAVVQTLIDYASDIGRVP 242
S NKM SN+A++ PNLL +EG +M++ T + AV++ +I +A
Sbjct: 389 SDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV---VAVIEPIIQHAD------ 439
Query: 243 DFILEKIPAML--GIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKP 299
F E++ + L S F G G +RKR S+ + K P
Sbjct: 440 WFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESP 498
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
sapiens]
Length = 433
Score = 74.7 bits (182), Expect = 2e-13
Identities = 60/183 (32%), Positives = 90/183 (49%), Gaps = 10/183 (5%)
Query: 65 IPSFLVDACTSL-EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDI---AGL 120
IP L T L E + TEGLFR+S SV ++ ++ + G+ ++ DI A +
Sbjct: 209 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP-VNFDDYGDIHIPAVI 267
Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
LK F RELP+P+L +E +L + + + + L +H VLRY FL
Sbjct: 268 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHA 327
Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
VS S NKM+SSNLA +F NL+ S+G +S+ + + LI+Y I
Sbjct: 328 VSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNM-----FTELLIEYYEKIFS 382
Query: 241 VPD 243
P+
Sbjct: 383 TPE 385
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
sapiens]
Length = 464
Score = 74.7 bits (182), Expect = 2e-13
Identities = 60/183 (32%), Positives = 90/183 (49%), Gaps = 10/183 (5%)
Query: 65 IPSFLVDACTSL-EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDI---AGL 120
IP L T L E + TEGLFR+S SV ++ ++ + G+ ++ DI A +
Sbjct: 240 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP-VNFDDYGDIHIPAVI 298
Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
LK F RELP+P+L +E +L + + + + L +H VLRY FL
Sbjct: 299 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHA 358
Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
VS S NKM+SSNLA +F NL+ S+G +S+ + + LI+Y I
Sbjct: 359 VSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNM-----FTELLIEYYEKIFS 413
Query: 241 VPD 243
P+
Sbjct: 414 TPE 416
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 73.9 bits (180), Expect = 3e-13
Identities = 55/173 (31%), Positives = 86/173 (49%), Gaps = 10/173 (5%)
Query: 70 VDACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSS--APPCDIAGLLKQFF 125
++AC L E + EGLFR +LK LK +D L + P +AG LK +
Sbjct: 269 IEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYL 328
Query: 126 RELPEPILPADLHEALLKAQQLGTEEKNKATLLLSC-LLADHTVHVLRYFFNFLRNVSLR 184
RELPEP++ +L+E + + ++K L +C L RY FL ++
Sbjct: 329 RELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQT 388
Query: 185 SSENKMDSSNLAVIFAPNLL-QTSEGH-EKMSSNTEKKLRLQAAVVQTLIDYA 235
S NKM SN+A++ PNLL +EG +M++ T + AV++ +I +A
Sbjct: 389 SDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV---VAVIEPIIQHA 438
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 73.6 bits (179), Expect = 4e-13
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 7/171 (4%)
Query: 51 FNALPHSAVPEYGHIPSFLVDACTSLED--HIHTEGLFRKSGSVIRLKALKNKVDHGEGC 108
FN + + + G +V++C + + +G+FR GS + + +KN + GE
Sbjct: 504 FNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDP 563
Query: 109 L----SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQL-GTEEKNKATLLLSCLL 163
L + +AG+LK +FR L P+ P + + L+ +L E+ + L
Sbjct: 564 LVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTL 623
Query: 164 ADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMS 214
+ V+RY F FL ++S S EN MD NLA+ F P L+ +G + +S
Sbjct: 624 PRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVS 674
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/173 (31%), Positives = 83/173 (47%), Gaps = 5/173 (2%)
Query: 45 KIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVD 103
K+FGV L + E G IP+ + + L H + EGLFR +G+V ++ L+ K +
Sbjct: 39 KLFGVSLQELERQGLTENG-IPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFE 97
Query: 104 HGEGCL--SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLL-LS 160
G C A LLK F RELP+ ++ + L ++ Q G + +++L L
Sbjct: 98 SGVPVELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLI 157
Query: 161 CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKM 213
L D +L+Y FL V+ +N+M+ NLA +F PN G E M
Sbjct: 158 KELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGM 210
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 70.9 bits (172), Expect = 3e-12
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
Query: 43 GGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALKN 100
GG IFG + LV+ C + + EGLFR G +K L++
Sbjct: 34 GGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQD 93
Query: 101 KVDHGE--GCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLL 158
D GE S+ +A LLK + RELPEP++P +E L +L ++E+
Sbjct: 94 AFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKE 153
Query: 159 LSCLLADHTV---HVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQ 205
L+ + V ++L+Y FL V S NKM NLA +F PN+L+
Sbjct: 154 LAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR 203
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 70.9 bits (172), Expect = 3e-12
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
Query: 43 GGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALKN 100
GG IFG + LV+ C + + EGLFR G +K L++
Sbjct: 129 GGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQD 188
Query: 101 KVDHGE--GCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLL 158
D GE S+ +A LLK + RELPEP++P +E L +L ++E+
Sbjct: 189 AFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKE 248
Query: 159 LSCLLADHTV---HVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQ 205
L+ + V ++L+Y FL V S NKM NLA +F PN+L+
Sbjct: 249 LAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR 298
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 70.9 bits (172), Expect = 3e-12
Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
Query: 80 IHTEGLFRKSGSVIRLKALKNKVDHGEGCL----SSAPPCDIAGLLKQFFRELPEPILPA 135
+ +G+FR GS + + +KN + GE L + +AG+LK +FR L P+ P
Sbjct: 511 LQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPK 570
Query: 136 DLHEALLKAQQL-GTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSN 194
+ + L+ +L E+ + L + V+RY F FL ++S S EN MD N
Sbjct: 571 ERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYN 630
Query: 195 LAVIFAPNLLQTSEGHEKMS 214
LA+ F P L+ +G + +S
Sbjct: 631 LAICFGPTLMHIPDGQDPVS 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,901,352
Number of Sequences: 37866
Number of extensions: 858859
Number of successful extensions: 2511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2222
Number of HSP's gapped (non-prelim): 174
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.