Guide to the Human Genome
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Search of human proteins with 40556376

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
         (553 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]        1107   0.0  
gi|23308751 3-hydroxyisobutyrate dehydrogenase [Homo sapiens]         110   4e-24
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho...    71   3e-12
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]     69   1e-11
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    57   4e-08
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    57   4e-08
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...    56   1e-07
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo...    56   1e-07
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...    56   1e-07
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                51   3e-06
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]               51   3e-06
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]      50   5e-06
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi...    49   2e-05
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...    48   3e-05
gi|4504191 mutS homolog 6 [Homo sapiens]                               47   5e-05
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           46   8e-05
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           46   8e-05
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    45   2e-04
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    45   2e-04
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    45   2e-04
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    45   2e-04
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    45   2e-04
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...    45   2e-04
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       44   3e-04
gi|116812577 LUC7-like 2 [Homo sapiens]                                44   5e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    43   9e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           43   9e-04
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           43   9e-04
gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    42   0.002
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ...    42   0.002

>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
          Length = 553

 Score = 1107 bits (2863), Expect = 0.0
 Identities = 553/553 (100%), Positives = 553/553 (100%)

Query: 1   MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQL 60
           MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQL
Sbjct: 1   MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQL 60

Query: 61  KPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRP 120
           KPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRP
Sbjct: 61  KPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRP 120

Query: 121 NSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKD 180
           NSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKD
Sbjct: 121 NSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKD 180

Query: 181 LTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLK 240
           LTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLK
Sbjct: 181 LTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLK 240

Query: 241 ICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTA 300
           ICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTA
Sbjct: 241 ICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTA 300

Query: 301 EKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDM 360
           EKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDM
Sbjct: 301 EKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDM 360

Query: 361 STVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAM 420
           STVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAM
Sbjct: 361 STVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAM 420

Query: 421 GKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASI 480
           GKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASI
Sbjct: 421 GKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASI 480

Query: 481 FLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQS 540
           FLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQS
Sbjct: 481 FLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQS 540

Query: 541 DNDMSAVYRAYIH 553
           DNDMSAVYRAYIH
Sbjct: 541 DNDMSAVYRAYIH 553


>gi|23308751 3-hydroxyisobutyrate dehydrogenase [Homo sapiens]
          Length = 336

 Score =  110 bits (274), Expect = 4e-24
 Identities = 77/304 (25%), Positives = 130/304 (42%), Gaps = 7/304 (2%)

Query: 253 AADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 312
           A    AV      +   +GF+GLG MG+ +  NL+K G+ + +++   + C  F   G +
Sbjct: 25  AGSFAAVCSRSVASKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQ 84

Query: 313 LGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELA 372
           +  +PA+V    D     +     A +   G +G+L+ ++ G   +D ST+D     ELA
Sbjct: 85  VVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELA 144

Query: 373 QVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGN 432
           + +   G  F++APVSG    +  G L  +  G    +         MG    + G VG 
Sbjct: 145 KEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGT 204

Query: 433 AAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILN--QGQLASIFLDQKCQNIL 490
                +  NM+    M   AE + L    G   + L  ILN   G+  S         ++
Sbjct: 205 GQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVM 264

Query: 491 QG-----NFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMS 545
            G     N++  F    + KDL LA     +   P  + + A+++Y+   A   S  D S
Sbjct: 265 DGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFS 324

Query: 546 AVYR 549
           +V++
Sbjct: 325 SVFQ 328


>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
           sapiens]
          Length = 203

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 55/195 (28%), Positives = 92/195 (47%), Gaps = 24/195 (12%)

Query: 7   RLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAH 66
           + GDLV+ K+  YP WP +I   P+   KP   K + + FFGT + A++  + L PY  +
Sbjct: 10  KAGDLVFAKMKGYPHWPARIDELPEGAVKPPANK-YPIFFFGTHETAFLGPKDLFPYKEY 68

Query: 67  KEEMIKINKGKRFQQAVDAVE-----EFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPN 121
           K++  K NK K F + +  +E     +F      + Q+SS    +  N  ++S E     
Sbjct: 69  KDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSE----- 123

Query: 122 SGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDL 181
                      EG   +  G+GK++     S+R      K++ +QS +  G   +D+KD 
Sbjct: 124 ----------EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPG--DEDDKDC 171

Query: 182 TIPES-STVKGMMAG 195
              E+ S+ +G  AG
Sbjct: 172 KEEENKSSSEGGDAG 186


>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 64/215 (29%), Positives = 94/215 (43%), Gaps = 21/215 (9%)

Query: 7   RLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAH 66
           + GDLV+ K+  YP WP +I   P+   K    K + V FFGT + A++  + L PY   
Sbjct: 11  KCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANK-YQVFFFGTHETAFLGPKDLFPYEES 69

Query: 67  KEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
           KE+  K NK K F + +  +E          + S + SS  K+     E       GD  
Sbjct: 70  KEKFGKPNKRKGFSEGLWEIEN-----NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD 124

Query: 127 RKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQ----EQSPR--KRGRPPKDEKD 180
           +K   +EG   +   EGK  +   + E+  K  LKR      E SP+  K    P+ E+ 
Sbjct: 125 KK-GNAEGSSDE---EGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE- 179

Query: 181 LTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADP 215
               E++T++     PM   K   T SEP     P
Sbjct: 180 ---KEAATLEVERPLPMEVEK-NSTPSEPGSGRGP 210


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 60/241 (24%), Positives = 98/241 (40%), Gaps = 44/241 (18%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
           GDLV+ K+  YP WP +I +      KP   K + + FFGT + A++  + L PY   K+
Sbjct: 8   GDLVFAKMKGYPHWPARIDDIADGAVKPPPNK-YPIFFFGTHETAFLGPKDLFPYDKCKD 66

Query: 69  EMIKINKGKRFQQAV---------------------------------DAVEEFLRRAKG 95
           +  K NK K F + +                                 DA E+   R   
Sbjct: 67  KYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVM 126

Query: 96  KDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERG 155
                +  ++ D+   +S  ++S  NSG  KRK    +  V K     + R +S   ++ 
Sbjct: 127 AVTAVTATAASDRMESDSDSDKSSDNSG-LKRKTPALKMSVSK-----RARKASSDLDQA 180

Query: 156 SKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQ--PTASEPVKDA 213
           S SP +  +E S          ++D T  + + V+    GP+   K +  P+AS+    A
Sbjct: 181 SVSPSE--EENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKA 238

Query: 214 D 214
           D
Sbjct: 239 D 239



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 34/148 (22%), Positives = 61/148 (41%), Gaps = 29/148 (19%)

Query: 67  KEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEE--------RS 118
           K   +K++  KR ++A   +++       ++ + S + S+  + ++ + E        R 
Sbjct: 158 KTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRR 217

Query: 119 RPNSGDEKRKLSLSEGKVKKNMGEGKK-------RVSSGSSERGSKSPL----------- 160
            P  G +K+K   +     K   +G K       R +S SS   S S             
Sbjct: 218 GPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGR 277

Query: 161 KRAQEQSPRKRGRPPKDEKDLTIPESST 188
           K A++  P+ RGR PK E+    P SS+
Sbjct: 278 KPAEKPLPKPRGRKPKPERP---PSSSS 302



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 13/129 (10%)

Query: 83  VDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGE 142
           VD + E+ RR + + +        +  RR   EE  R     EK +      +  +   E
Sbjct: 310 VDRISEWKRRDEARRREL------EARRRREQEEELRRLREQEKEEKERRRERADRGEAE 363

Query: 143 GKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKW 202
                SSG   R    P+K+   +  + RGR P    D + PE+   +       +A K 
Sbjct: 364 RGSGGSSGDELREDDEPVKK---RGRKGRGRGPPSSSD-SEPEAELER---EAKKSAKKP 416

Query: 203 QPTASEPVK 211
           Q +++EP +
Sbjct: 417 QSSSTEPAR 425


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 60/241 (24%), Positives = 98/241 (40%), Gaps = 44/241 (18%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
           GDLV+ K+  YP WP +I +      KP   K + + FFGT + A++  + L PY   K+
Sbjct: 8   GDLVFAKMKGYPHWPARIDDIADGAVKPPPNK-YPIFFFGTHETAFLGPKDLFPYDKCKD 66

Query: 69  EMIKINKGKRFQQAV---------------------------------DAVEEFLRRAKG 95
           +  K NK K F + +                                 DA E+   R   
Sbjct: 67  KYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVM 126

Query: 96  KDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERG 155
                +  ++ D+   +S  ++S  NSG  KRK    +  V K     + R +S   ++ 
Sbjct: 127 AVTAVTATAASDRMESDSDSDKSSDNSG-LKRKTPALKMSVSK-----RARKASSDLDQA 180

Query: 156 SKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQ--PTASEPVKDA 213
           S SP +  +E S          ++D T  + + V+    GP+   K +  P+AS+    A
Sbjct: 181 SVSPSE--EENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKA 238

Query: 214 D 214
           D
Sbjct: 239 D 239



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 34/148 (22%), Positives = 61/148 (41%), Gaps = 29/148 (19%)

Query: 67  KEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEE--------RS 118
           K   +K++  KR ++A   +++       ++ + S + S+  + ++ + E        R 
Sbjct: 158 KTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRR 217

Query: 119 RPNSGDEKRKLSLSEGKVKKNMGEGKK-------RVSSGSSERGSKSPL----------- 160
            P  G +K+K   +     K   +G K       R +S SS   S S             
Sbjct: 218 GPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGR 277

Query: 161 KRAQEQSPRKRGRPPKDEKDLTIPESST 188
           K A++  P+ RGR PK E+    P SS+
Sbjct: 278 KPAEKPLPKPRGRKPKPERP---PSSSS 302



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 13/129 (10%)

Query: 83  VDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGE 142
           VD + E+ RR + + +        +  RR   EE  R     EK +      +  +   E
Sbjct: 310 VDRISEWKRRDEARRREL------EARRRREQEEELRRLREQEKEEKERRRERADRGEAE 363

Query: 143 GKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKW 202
                SSG   R    P+K+   +  + RGR P    D + PE+   +       +A K 
Sbjct: 364 RGSGGSSGDELREDDEPVKK---RGRKGRGRGPPSSSD-SEPEAELER---EAKKSAKKP 416

Query: 203 QPTASEPVK 211
           Q +++EP +
Sbjct: 417 QSSSTEPAR 425


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 14/188 (7%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
           GDL++ K+  YP WP ++   P    KP   K   + FFGT + A++  + + PY  +KE
Sbjct: 8   GDLIFAKMKGYPHWPARVDEVPDGAVKPPTNK-LPIFFFGTHETAFLGPKDIFPYSENKE 66

Query: 69  EMIKINKGKRFQQAVDAVEE--FLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
           +  K NK K F + +  ++    ++ +  +  T   N+S D          S+ ++  E+
Sbjct: 67  KYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEE 126

Query: 127 RKLSLSEGK-----VKKNMGEGKKRVSSGSSERGSKSPLKRAQ-----EQSPRKRGRPPK 176
           +  +    K       K    G+KR +    E      +  A      + SP KRGRP  
Sbjct: 127 KASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSP-KRGRPAA 185

Query: 177 DEKDLTIP 184
            E  +  P
Sbjct: 186 TEVKIPKP 193


>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 14/188 (7%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
           GDL++ K+  YP WP ++   P    KP   K   + FFGT + A++  + + PY  +KE
Sbjct: 8   GDLIFAKMKGYPHWPARVDEVPDGAVKPPTNK-LPIFFFGTHETAFLGPKDIFPYSENKE 66

Query: 69  EMIKINKGKRFQQAVDAVEE--FLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
           +  K NK K F + +  ++    ++ +  +  T   N+S D          S+ ++  E+
Sbjct: 67  KYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEE 126

Query: 127 RKLSLSEGK-----VKKNMGEGKKRVSSGSSERGSKSPLKRAQ-----EQSPRKRGRPPK 176
           +  +    K       K    G+KR +    E      +  A      + SP KRGRP  
Sbjct: 127 KASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSP-KRGRPAA 185

Query: 177 DEKDLTIP 184
            E  +  P
Sbjct: 186 TEVKIPKP 193


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 14/188 (7%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
           GDL++ K+  YP WP ++   P    KP   K   + FFGT + A++  + + PY  +KE
Sbjct: 8   GDLIFAKMKGYPHWPARVDEVPDGAVKPPTNK-LPIFFFGTHETAFLGPKDIFPYSENKE 66

Query: 69  EMIKINKGKRFQQAVDAVEE--FLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
           +  K NK K F + +  ++    ++ +  +  T   N+S D          S+ ++  E+
Sbjct: 67  KYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEE 126

Query: 127 RKLSLSEGK-----VKKNMGEGKKRVSSGSSERGSKSPLKRAQ-----EQSPRKRGRPPK 176
           +  +    K       K    G+KR +    E      +  A      + SP KRGRP  
Sbjct: 127 KASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSP-KRGRPAA 185

Query: 177 DEKDLTIP 184
            E  +  P
Sbjct: 186 TEVKIPKP 193


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 24/125 (19%)

Query: 4   VSLRLGDLVWGKLGRYPPWPGKIVNPPK----DLKKPRGKKCFFVKFFGTE-DHAWIKVE 58
           V  ++GDLVW K+G YP WP  + + P+         RG + + V+FF  + + AW+  +
Sbjct: 266 VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEK 325

Query: 59  QLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERS 118
           +++ Y  HK+                  EE L  A+   Q S+H+      +     ER+
Sbjct: 326 RVREYKGHKQ-----------------YEELL--AEATKQASNHSEKQKIRKPRPQRERA 366

Query: 119 RPNSG 123
           + + G
Sbjct: 367 QWDIG 371



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 10/114 (8%)

Query: 2    AAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKK----CFFVKFFGTEDHAWIKV 57
            A   L    +VW KLG Y  WP +I NP       +G K     F V FFG+ D+ W+  
Sbjct: 954  AGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQ 1013

Query: 58   EQLKPY----HAHKEEMIKINK--GKRFQQAVDAVEEFLRRAKGKDQTSSHNSS 105
             ++ PY     +  E    INK   K  ++A    +E   + + K+      +S
Sbjct: 1014 GRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNS 1067


>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
          Length = 645

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 24/125 (19%)

Query: 4   VSLRLGDLVWGKLGRYPPWPGKIVNPPK----DLKKPRGKKCFFVKFFGTE-DHAWIKVE 58
           V  ++GDLVW K+G YP WP  + + P+         RG + + V+FF  + + AW+  +
Sbjct: 266 VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEK 325

Query: 59  QLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERS 118
           +++ Y  HK+                  EE L  A+   Q S+H+      +     ER+
Sbjct: 326 RVREYKGHKQ-----------------YEELL--AEATKQASNHSEKQKIRKPRPQRERA 366

Query: 119 RPNSG 123
           + + G
Sbjct: 367 QWDIG 371


>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
          Length = 251

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 18/169 (10%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
           GDLV+ KL  Y  WP +I    + + +P   + FF   FGT + A++  ++L PY   KE
Sbjct: 12  GDLVFAKLKGYAHWPARI----EHMTQPNRYQVFF---FGTHETAFLSPKRLFPYKECKE 64

Query: 69  EMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRK 128
           +  K NK + F   +  +E          Q S    + +K   +          GDE + 
Sbjct: 65  KFGKPNKRRGFSAGLWEIEN-----NPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKP 119

Query: 129 LSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKD 177
                G      G+   +          K PLKR+    P    + PK+
Sbjct: 120 THAGGG------GDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKE 162


>gi|186928819 hepatoma-derived growth factor isoform b [Homo
           sapiens]
          Length = 256

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 56/199 (28%), Positives = 82/199 (41%), Gaps = 21/199 (10%)

Query: 23  PGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQA 82
           P  I   P+   K    K + V FFGT + A++  + L PY   KE+  K NK K F + 
Sbjct: 43  PHTIDEMPEAAVKSTANK-YQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEG 101

Query: 83  VDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGE 142
           +  +E          + S + SS  K+     E       GD  +K   +EG   +   E
Sbjct: 102 LWEIEN-----NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK-GNAEGSSDE---E 152

Query: 143 GKKRVSSGSSERGSKSPLKRAQ----EQSPR--KRGRPPKDEKDLTIPESSTVKGMMAGP 196
           GK  +   + E+  K  LKR      E SP+  K    P+ E+     E++T++     P
Sbjct: 153 GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE----KEAATLEVERPLP 208

Query: 197 MAAFKWQPTASEPVKDADP 215
           M   K   T SEP     P
Sbjct: 209 MEVEK-NSTPSEPGSGRGP 226


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
           sapiens]
          Length = 233

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 51/178 (28%), Positives = 75/178 (42%), Gaps = 20/178 (11%)

Query: 44  VKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHN 103
           V FFGT + A++  + L PY   KE+  K NK K F + +  +E          + S + 
Sbjct: 40  VFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIEN-----NPTVKASGYQ 94

Query: 104 SSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRA 163
           SS  K+     E       GD  +K   +EG   +   EGK  +   + E+  K  LKR 
Sbjct: 95  SSQKKSCVEEPEPEPEAAEGDGDKK-GNAEGSSDE---EGKLVIDEPAKEKNEKGALKRR 150

Query: 164 Q----EQSPR--KRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADP 215
                E SP+  K    P+ E+     E++T++     PM   K   T SEP     P
Sbjct: 151 AGDLLEDSPKRPKEAENPEGEE----KEAATLEVERPLPMEVEK-NSTPSEPGSGRGP 203


>gi|4504191 mutS homolog 6 [Homo sapiens]
          Length = 1360

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 41/167 (24%), Positives = 68/167 (40%), Gaps = 14/167 (8%)

Query: 9   GDLVWGKLGRYPPWPGKIVNPPKD--LKKPRGKKC-FFVKFF-GTEDHAWIKVEQLKPYH 64
           GDLVW K+  YP WP  + N P D    + +GK     V+FF  +    W+    LKPY 
Sbjct: 93  GDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYT 152

Query: 65  AHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGD 124
             K +  +  KG  F  A   +   ++RA           + DK +R        P+  +
Sbjct: 153 GSKSK--EAQKGGHFYSAKPEILRAMQRA-------DEALNKDKIKRLELAVCDEPSEPE 203

Query: 125 EKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKR 171
           E+ ++ +    V  +  E    + S    +      +R+  Q  ++R
Sbjct: 204 EEEEMEVGTTYV-TDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRR 249


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 24/164 (14%)

Query: 24  GKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQ--------LKPYHAHKEEMIKINK 75
           GK V P   LK+   K+    +    ED +  K+++        L  Y+    E    NK
Sbjct: 136 GKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNK 195

Query: 76  GKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGK 135
            K  +++         +++     SS  SS   + R+ S  RSR +S  + R  S S   
Sbjct: 196 KKSNRRSRS-------KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR-- 246

Query: 136 VKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSP------RKRGR 173
            +++   G K  SS  S RGS SP KR+   S       RKR R
Sbjct: 247 -ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 92  RAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGS 151
           R     +  S++SS     RN    RSR +S  +++K      + +    E + R SSGS
Sbjct: 264 RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK-----RRTRSRSPERRHRSSSGS 318

Query: 152 SERGSKSPLKR 162
           S  GS+S  K+
Sbjct: 319 SHSGSRSSSKK 329


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 24/164 (14%)

Query: 24  GKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQ--------LKPYHAHKEEMIKINK 75
           GK V P   LK+   K+    +    ED +  K+++        L  Y+    E    NK
Sbjct: 136 GKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNK 195

Query: 76  GKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGK 135
            K  +++         +++     SS  SS   + R+ S  RSR +S  + R  S S   
Sbjct: 196 KKSNRRSRS-------KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR-- 246

Query: 136 VKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSP------RKRGR 173
            +++   G K  SS  S RGS SP KR+   S       RKR R
Sbjct: 247 -ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 92  RAKGKDQTSSHNSSDDKNRRNSSEERSR-PNSGDEKRKLSLSEGKVKKNMGEGKKR 146
           R     +  S++SS     RN    RSR  +SGD K++ + S     + +GE  K+
Sbjct: 264 RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQVIGENTKQ 319


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 12/123 (9%)

Query: 2   AAVSLRLGDLVWGKLGRYPPWPGKIVNP---PKDLKKPRGKKCFF-VKFFGTEDHAWIKV 57
           A   L   D++W KLG Y  WP ++ +P   P +++K + +   F V FFG++D+ W   
Sbjct: 874 AGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQ 933

Query: 58  EQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEER 117
            ++ PY       ++ ++G R+ Q V  +    + A  + +         +  R + E  
Sbjct: 934 ARVFPY-------MEGDRGSRY-QGVRGIGRVFKNALQEAEARFREIKLQREARETQESE 985

Query: 118 SRP 120
            +P
Sbjct: 986 RKP 988



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281

Query: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340

Query: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398

Query: 171 RGRPPK 176
           R R  K
Sbjct: 399 RRRRAK 404


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 12/123 (9%)

Query: 2   AAVSLRLGDLVWGKLGRYPPWPGKIVNP---PKDLKKPRGKKCFF-VKFFGTEDHAWIKV 57
           A   L   D++W KLG Y  WP ++ +P   P +++K + +   F V FFG++D+ W   
Sbjct: 874 AGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQ 933

Query: 58  EQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEER 117
            ++ PY       ++ ++G R+ Q V  +    + A  + +         +  R + E  
Sbjct: 934 ARVFPY-------MEGDRGSRY-QGVRGIGRVFKNALQEAEARFREIKLQREARETQESE 985

Query: 118 SRP 120
            +P
Sbjct: 986 RKP 988



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281

Query: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340

Query: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398

Query: 171 RGRPPK 176
           R R  K
Sbjct: 399 RRRRAK 404


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 12/123 (9%)

Query: 2   AAVSLRLGDLVWGKLGRYPPWPGKIVNP---PKDLKKPRGKKCFF-VKFFGTEDHAWIKV 57
           A   L   D++W KLG Y  WP ++ +P   P +++K + +   F V FFG++D+ W   
Sbjct: 874 AGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQ 933

Query: 58  EQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEER 117
            ++ PY       ++ ++G R+ Q V  +    + A  + +         +  R + E  
Sbjct: 934 ARVFPY-------MEGDRGSRY-QGVRGIGRVFKNALQEAEARFREIKLQREARETQESE 985

Query: 118 SRP 120
            +P
Sbjct: 986 RKP 988



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281

Query: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340

Query: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398

Query: 171 RGRPPK 176
           R R  K
Sbjct: 399 RRRRAK 404


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 12/123 (9%)

Query: 2   AAVSLRLGDLVWGKLGRYPPWPGKIVNP---PKDLKKPRGKKCFF-VKFFGTEDHAWIKV 57
           A   L   D++W KLG Y  WP ++ +P   P +++K + +   F V FFG++D+ W   
Sbjct: 874 AGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQ 933

Query: 58  EQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEER 117
            ++ PY       ++ ++G R+ Q V  +    + A  + +         +  R + E  
Sbjct: 934 ARVFPY-------MEGDRGSRY-QGVRGIGRVFKNALQEAEARFREIKLQREARETQESE 985

Query: 118 SRP 120
            +P
Sbjct: 986 RKP 988



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281

Query: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340

Query: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398

Query: 171 RGRPPK 176
           R R  K
Sbjct: 399 RRRRAK 404


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 12/110 (10%)

Query: 10   DLVWGKLGRYPPWPGKIVNP---PKDLKKPRGKKCFF-VKFFGTEDHAWIKVEQLKPY-H 64
            ++VW K+GRY  WP +I +P   P ++ K R     F V FFG+ D+ W    ++ PY  
Sbjct: 1489 EIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYME 1548

Query: 65   AHKEEMIKINKG------KRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDK 108
                   K+ KG      K  Q+A    EE L+  K   Q      +D K
Sbjct: 1549 GDVSSKDKMGKGVDGTYKKALQEAAARFEE-LKAQKELRQLQEDRKNDKK 1597



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 11/82 (13%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP-------KDLKKPRGKKCFFVKFFG-TEDHAWI---K 56
           +GDL+W K  R P WP +I + P         +   R  + ++V+ FG   + AW+    
Sbjct: 54  VGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKA 113

Query: 57  VEQLKPYHAHKEEMIKINKGKR 78
           +   +  H  +E  +   +GK+
Sbjct: 114 IVMFEGRHQFEELPVLRRRGKQ 135


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
            [Homo sapiens]
          Length = 2696

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 12/110 (10%)

Query: 10   DLVWGKLGRYPPWPGKIVNP---PKDLKKPRGKKCFF-VKFFGTEDHAWIKVEQLKPY-H 64
            ++VW K+GRY  WP +I +P   P ++ K R     F V FFG+ D+ W    ++ PY  
Sbjct: 1758 EIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYME 1817

Query: 65   AHKEEMIKINKG------KRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDK 108
                   K+ KG      K  Q+A    EE L+  K   Q      +D K
Sbjct: 1818 GDVSSKDKMGKGVDGTYKKALQEAAARFEE-LKAQKELRQLQEDRKNDKK 1866



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 11/82 (13%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP-------KDLKKPRGKKCFFVKFFG-TEDHAWI---K 56
           +GDL+W K  R P WP +I + P         +   R  + ++V+ FG   + AW+    
Sbjct: 323 VGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKA 382

Query: 57  VEQLKPYHAHKEEMIKINKGKR 78
           +   +  H  +E  +   +GK+
Sbjct: 383 IVMFEGRHQFEELPVLRRRGKQ 404


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 7/144 (4%)

Query: 60  LKPYHAHKEEMIKINK----GKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSE 115
           L+ Y +  EE  +I++    G R      + +  L     K  T   + S  K R     
Sbjct: 137 LQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRS 196

Query: 116 ERSRPNSGDE--KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGR 173
           ++ +   G E  K K + S+ K +K      KR  S    R SKSP  R + Q    + R
Sbjct: 197 DKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKAR 256

Query: 174 PPKDEKDLTIPESSTVKGMMAGPM 197
            P D+K + I + S  K     P+
Sbjct: 257 SPTDDK-VKIEDKSKSKDRKKSPI 279



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 91  RRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSG 150
           RRAK +   S      +  RR  S  R+RP      R+   S+     N     +R S  
Sbjct: 390 RRAKSR---SLERKRREPERRRLSSPRTRPRDDILSRR-ERSKDASPINRWSPTRRRSRS 445

Query: 151 SSERGSKSPLKRAQEQSPRKRGRPPK 176
              R S+SPL+R+  +SPR+R R P+
Sbjct: 446 PIRRRSRSPLRRS--RSPRRRSRSPR 469



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 13/97 (13%)

Query: 92  RAKGKDQTSSHNSSDDKNRRNS---SEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVS 148
           R+   D+    + S  K+R+ S   +E RSR      +  + L  GK K      K+R S
Sbjct: 256 RSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDL-RGKSKDRRSRSKERKS 314

Query: 149 SGSSERGSKSPLKR--------AQEQSPRKR-GRPPK 176
             S     K P+K          + +SP +R GR PK
Sbjct: 315 KRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPK 351



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 23/122 (18%)

Query: 74  NKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRP--------NSGDE 125
           ++GK+ +  VD       R K KD+ S   S + K++R+ +++  +P        +SG E
Sbjct: 287 DRGKKSRSPVDL------RGKSKDRRS--RSKERKSKRSETDKEKKPIKSPSKDASSGKE 338

Query: 126 KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPL----KRAQEQSPRKRGRPPKDEKDL 181
            R  S   G+  K      K        R S+SPL    +  Q +SP +   P +  K  
Sbjct: 339 NRSPSRRPGRSPKRRSLSPK---PRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSR 395

Query: 182 TI 183
           ++
Sbjct: 396 SL 397



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 90  LRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLS---EGKVKKNMGEGKKR 146
           LRR++   + S      D+ RR+ S  R R  S   +R+ S S   E K K ++ EG K 
Sbjct: 455 LRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKV 514

Query: 147 VSSGSSE 153
               SS+
Sbjct: 515 EQESSSD 521


>gi|116812577 LUC7-like 2 [Homo sapiens]
          Length = 392

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 8/128 (6%)

Query: 56  KVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNR-RNSS 114
           K+E+LK   A K+E     + KR ++      E LRR++      SH+ +  ++R R   
Sbjct: 224 KLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSR------SHSKNPKRSRSREHR 277

Query: 115 EERSRPNSGDEKRKL-SLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGR 173
             RSR  S + KR+  S S  K  ++      R  S S +R   S   R++E+S R+  +
Sbjct: 278 RHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK 337

Query: 174 PPKDEKDL 181
               ++DL
Sbjct: 338 ERFRDQDL 345



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 92  RAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGS 151
           R+K +++   H S      R+ S +RSR +S D  R+ S      ++   +    ++S  
Sbjct: 293 RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQD---LASCD 349

Query: 152 SERGSKSPLKRAQEQSPRKR 171
            +R S+    R +++  +KR
Sbjct: 350 RDRSSRDRSPRDRDRKDKKR 369


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 47/208 (22%), Positives = 76/208 (36%), Gaps = 27/208 (12%)

Query: 67  KEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
           K++  KI      +  +++ E      K K  + + N    KN   S++  S P    +K
Sbjct: 397 KKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 456

Query: 127 RKLSLSEGKVKKNMGEGKK--RVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDLTIP 184
            K    +GK      + KK  + ++ S+E  S   LK+ ++ S  K+G     +KD    
Sbjct: 457 GKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKD 516

Query: 185 ESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEE 244
             ST           FK     S  +K +D          TE     Y+   KK      
Sbjct: 517 TESTDAEFDESSKTGFK----TSTKIKGSD----------TESEESLYKPGAKK------ 556

Query: 245 ETGSTSIQAADSTAVNGSITPTDKKIGF 272
                 I  +D T+ N  +   + K GF
Sbjct: 557 -----KIDESDGTSANSKMEGLESKRGF 579


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)

Query: 75   KGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEG 134
            K K+ +      +E  R +  + ++    SS+ K+R+ +SE RSR      K K   S+ 
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT 1861

Query: 135  KVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSP--RKRGRPPKDEKDLTIPESSTVKGM 192
            + +      ++   S S  RG +S  K  +++SP  R + R  K ++  +     TV+  
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRAR 1921

Query: 193  MAGP 196
               P
Sbjct: 1922 SRTP 1925



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 4/121 (3%)

Query: 56   KVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNS---SDDKNRRN 112
            K E+ K   +      K +K    +      E   R  K   ++ SH S   S  ++RR 
Sbjct: 1811 KGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR 1870

Query: 113  SSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRG 172
                RSR  S   +        +  K+  + ++R    SS R ++  + RA+ ++P +R 
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV-RARSRTPSRRS 1929

Query: 173  R 173
            R
Sbjct: 1930 R 1930


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)

Query: 75   KGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEG 134
            K K+ +      +E  R +  + ++    SS+ K+R+ +SE RSR      K K   S+ 
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT 1861

Query: 135  KVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSP--RKRGRPPKDEKDLTIPESSTVKGM 192
            + +      ++   S S  RG +S  K  +++SP  R + R  K ++  +     TV+  
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRAR 1921

Query: 193  MAGP 196
               P
Sbjct: 1922 SRTP 1925



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 4/121 (3%)

Query: 56   KVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNS---SDDKNRRN 112
            K E+ K   +      K +K    +      E   R  K   ++ SH S   S  ++RR 
Sbjct: 1811 KGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR 1870

Query: 113  SSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRG 172
                RSR  S   +        +  K+  + ++R    SS R ++  + RA+ ++P +R 
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV-RARSRTPSRRS 1929

Query: 173  R 173
            R
Sbjct: 1930 R 1930


>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
           [Homo sapiens]
          Length = 647

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281

Query: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340

Query: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398

Query: 171 RGRPPK 176
           R R  K
Sbjct: 399 RRRRAK 404


>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
           [Homo sapiens]
          Length = 629

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281

Query: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340

Query: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398

Query: 171 RGRPPK 176
           R R  K
Sbjct: 399 RRRRAK 404


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,990,466
Number of Sequences: 37866
Number of extensions: 953473
Number of successful extensions: 5219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 110
Number of HSP's successfully gapped in prelim test: 245
Number of HSP's that attempted gapping in prelim test: 4232
Number of HSP's gapped (non-prelim): 1012
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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