Guide to the Human Genome
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Search of human proteins with 40538799

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo
sapiens]
         (601 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo sa...  1175   0.0  
gi|16753203 ubiquilin 1 isoform 1 [Homo sapiens]                      688   0.0  
gi|16753207 ubiquilin 2 [Homo sapiens]                                666   0.0  
gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]                      627   e-180
gi|8567418 ubiquilin 3 [Homo sapiens]                                 306   3e-83
gi|145580580 ubiquilin-like [Homo sapiens]                            187   3e-47
gi|38158015 mastermind-like 3 [Homo sapiens]                           58   3e-08
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       55   2e-07
gi|4826964 UV excision repair protein RAD23 homolog A [Homo sapi...    55   2e-07
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       54   5e-07
gi|4506387 UV excision repair protein RAD23 homolog B [Homo sapi...    53   9e-07
gi|41152107 ubiquitin-like 7 [Homo sapiens]                            52   2e-06
gi|14249682 ubiquitin-like 7 [Homo sapiens]                            52   2e-06
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]    51   3e-06
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]     51   3e-06
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]     51   3e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     50   5e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     50   5e-06
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]    49   1e-05
gi|50345997 E1A binding protein p300 [Homo sapiens]                    48   3e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ...    47   4e-05
gi|238859557 regulatory factor X1 [Homo sapiens]                       44   3e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    44   4e-04
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    44   4e-04
gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]    44   6e-04
gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]    44   6e-04
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              44   6e-04
gi|241982780 programmed cell death 6 interacting protein isoform...    43   7e-04
gi|22027538 programmed cell death 6 interacting protein isoform ...    43   7e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          42   0.001

>gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo
           sapiens]
          Length = 601

 Score = 1175 bits (3039), Expect = 0.0
 Identities = 601/601 (100%), Positives = 601/601 (100%)

Query: 1   MAEPSGAETRPPIRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKI 60
           MAEPSGAETRPPIRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKI
Sbjct: 1   MAEPSGAETRPPIRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKI 60

Query: 61  LKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQ 120
           LKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQ
Sbjct: 61  LKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQ 120

Query: 121 PSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFME 180
           PSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFME
Sbjct: 121 PSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFME 180

Query: 181 LQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLN 240
           LQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLN
Sbjct: 181 LQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLN 240

Query: 241 NPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQ 300
           NPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQ
Sbjct: 241 NPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQ 300

Query: 301 FGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHP 360
           FGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHP
Sbjct: 301 FGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHP 360

Query: 361 TVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFA 420
           TVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFA
Sbjct: 361 TVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFA 420

Query: 421 AQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ 480
           AQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ
Sbjct: 421 AQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ 480

Query: 481 TEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQM 540
           TEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQM
Sbjct: 481 TEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQM 540

Query: 541 IQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGSQL 600
           IQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGSQL
Sbjct: 541 IQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGSQL 600

Query: 601 S 601
           S
Sbjct: 601 S 601


>gi|16753203 ubiquilin 1 isoform 1 [Homo sapiens]
          Length = 589

 Score =  688 bits (1775), Expect = 0.0
 Identities = 384/612 (62%), Positives = 449/612 (73%), Gaps = 62/612 (10%)

Query: 4   PSGAETRPP--IRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKIL 61
           P+ A +  P  ++VTVKTPK+KEE  + + +SV++FKEEIS+RFK+  DQLVLIFAGKIL
Sbjct: 26  PAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKIL 85

Query: 62  KDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQP 121
           KD DTL+QHGI DGLTVHLVIKT  + QD +A   ++      A +  TT +   TP   
Sbjct: 86  KDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNT------AGSNVTTSS---TPNSN 136

Query: 122 STSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMEL 181
           STSGSA+S+                            L G GG+ GL SLGL + NF EL
Sbjct: 137 STSGSATSNPFG-------------------------LGGLGGLAGLSSLGLNTTNFSEL 171

Query: 182 QQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNN 241
           Q QMQRQL+SNPEM+ QIMENP VQ M+SNPDLMR +IMANPQMQQL++RNPEISHMLNN
Sbjct: 172 QSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNN 231

Query: 242 PELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQF 301
           P++MRQT+ELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPM SAA+EQF
Sbjct: 232 PDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQF 291

Query: 302 GNNPFSSLAGNSDS-SSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGG-------S 353
           G NPF+SL  N+ S   SQP RTENR+PLPNPW+P    S +  SG   T G       S
Sbjct: 292 GGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTAS 351

Query: 354 GTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTL 413
           GTS    T  N        +G+ MFN+P MQ+LLQQI+ENPQLMQN++SAPYMRSMMQ+L
Sbjct: 352 GTSGQSTTAPN----LVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSL 407

Query: 414 AQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQ 473
           +QNPD AAQMM+N PLFAGNPQLQEQ+R QLP FLQQMQNP++LS ++NPRAMQALLQIQ
Sbjct: 408 SQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQ 467

Query: 474 QGLQTLQTEAPGLV----PSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGA 529
           QGLQTL TEAPGL+    P LG+ G +   + + GSNA  TP   TS   T  T+ P   
Sbjct: 468 QGLQTLATEAPGLIPGFTPGLGALGSTGGSSGTNGSNA--TPSENTS--PTAGTTEP--- 520

Query: 530 SSAQQQLMQQMIQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDIN 589
               QQ +QQM+Q LAG  N Q+Q PEVRFQQQLEQL++MGF+NREANLQALIATGGDIN
Sbjct: 521 --GHQQFIQQMLQALAGV-NPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDIN 577

Query: 590 AAIERLLGSQLS 601
           AAIERLLGSQ S
Sbjct: 578 AAIERLLGSQPS 589


>gi|16753207 ubiquilin 2 [Homo sapiens]
          Length = 624

 Score =  666 bits (1719), Expect = 0.0
 Identities = 374/642 (58%), Positives = 446/642 (69%), Gaps = 79/642 (12%)

Query: 2   AEPSGAETRPP--IRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGK 59
           A+ S A    P  I+VTVKTPK+KEE  + + +SV++FKE IS+RFK+Q DQLVLIFAGK
Sbjct: 20  AQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGK 79

Query: 60  ILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPA 119
           ILKD DTL QHGI DGLTVHLVIK+  + Q  +           P++A  T   S +TP 
Sbjct: 80  ILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQST---------QPSNAAGTNTTSASTPR 130

Query: 120 QPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFM 179
             ST  S +S+                            L   GG+ GL SLGL S NF 
Sbjct: 131 SNSTPISTNSNPFG-------------------------LGSLGGLAGLSSLGLSSTNFS 165

Query: 180 ELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHML 239
           ELQ QMQ+QLM++PEM+ QIMENP VQ M+SNPDLMR +IMANPQMQQL++RNPEISH+L
Sbjct: 166 ELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLL 225

Query: 240 NNPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAARE 299
           NNP++MRQT+E+ARNPAMMQEMMRNQD ALSNLESIPGGYNALRRMYTDIQEPM +AA+E
Sbjct: 226 NNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQE 285

Query: 300 QFGNNPFSSLAGNSDS-SSSQPLRTENREPLPNPWSPSPPT-SQAPGSGGEGTG-GSGTS 356
           QFG NPF+S+  +S S   +QP RTENR+PLPNPW+P P T S A  S    TG GSG S
Sbjct: 286 QFGGNPFASVGSSSSSGEGTQPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNS 345

Query: 357 QVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQN 416
             + T +    + AA+  + +F++P MQ+LLQQI+ENPQL+QN++SAPYMRSMMQ+L+QN
Sbjct: 346 SSNATGNT---VAAANYVASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQN 402

Query: 417 PDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGL 476
           PD AAQMM+N PLF  NPQLQEQ+R QLP FLQQMQNP++LS ++NPRAMQAL+QIQQGL
Sbjct: 403 PDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGL 462

Query: 477 QTLQTEAPGLVPS----------------------LGSFG-------------ISRT-PA 500
           QTL TEAPGL+PS                      +G  G             I  T PA
Sbjct: 463 QTLATEAPGLIPSFTPGVGVGVLGTAIGPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPA 522

Query: 501 PSAGSNAGSTPEAPTSSPATPA-TSSPTGASSAQQQLMQQMIQLLAGSGNSQVQTPEVRF 559
              GS     P  PT S A P+ T+SPT  S   QQ +QQM+Q LAG+   Q+  PEVRF
Sbjct: 523 APPGSTGSGGPTGPTVSSAAPSETTSPTSESGPNQQFIQQMVQALAGANAPQLPNPEVRF 582

Query: 560 QQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGSQLS 601
           QQQLEQLN+MGF+NREANLQALIATGGDINAAIERLLGSQ S
Sbjct: 583 QQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS 624


>gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]
          Length = 561

 Score =  627 bits (1617), Expect = e-180
 Identities = 361/612 (58%), Positives = 424/612 (69%), Gaps = 90/612 (14%)

Query: 4   PSGAETRPP--IRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKIL 61
           P+ A +  P  ++VTVKTPK+KEE  + + +SV++FKEEIS+RFK+  DQLVLIFAGKIL
Sbjct: 26  PAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKIL 85

Query: 62  KDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQP 121
           KD DTL+QHGI DGLTVHLVIKT  + QD +A   ++      A +  TT +   TP   
Sbjct: 86  KDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNT------AGSNVTTSS---TPNSN 136

Query: 122 STSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMEL 181
           STSGSA+S+                            L G GG+ GL SLGL + NF EL
Sbjct: 137 STSGSATSNPFG-------------------------LGGLGGLAGLSSLGLNTTNFSEL 171

Query: 182 QQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNN 241
           Q QMQRQL+SNPEM+ QIMENP VQ M+SNPDLMR +IMANPQMQQL++RNPEISHMLNN
Sbjct: 172 QSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNN 231

Query: 242 PELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQF 301
           P++MRQT+ELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPM SAA+EQF
Sbjct: 232 PDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQF 291

Query: 302 GNNPFSSLAGNSDS-SSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGG-------S 353
           G NPF+SL  N+ S   SQP RTENR+PLPNPW+P    S +  SG   T G       S
Sbjct: 292 GGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTAS 351

Query: 354 GTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTL 413
           GTS    T  N        +G+ MFN+P MQ+LLQQI+ENPQLMQN++SAPYMRSMMQ+L
Sbjct: 352 GTSGQSTTAPN----LVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSL 407

Query: 414 AQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQ 473
           +QNPD AA                            QMQNP++LS ++NPRAMQALLQIQ
Sbjct: 408 SQNPDLAA----------------------------QMQNPDTLSAMSNPRAMQALLQIQ 439

Query: 474 QGLQTLQTEAPGLV----PSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGA 529
           QGLQTL TEAPGL+    P LG+ G +   + + GSNA  TP   TS   T  T+ P   
Sbjct: 440 QGLQTLATEAPGLIPGFTPGLGALGSTGGSSGTNGSNA--TPSENTS--PTAGTTEP--- 492

Query: 530 SSAQQQLMQQMIQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDIN 589
               QQ +QQM+Q LAG  N Q+Q PEVRFQQQLEQL++MGF+NREANLQALIATGGDIN
Sbjct: 493 --GHQQFIQQMLQALAGV-NPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDIN 549

Query: 590 AAIERLLGSQLS 601
           AAIERLLGSQ S
Sbjct: 550 AAIERLLGSQPS 561


>gi|8567418 ubiquilin 3 [Homo sapiens]
          Length = 655

 Score =  306 bits (785), Expect = 3e-83
 Identities = 209/571 (36%), Positives = 292/571 (51%), Gaps = 81/571 (14%)

Query: 13  IRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGI 72
           I+VTVKTPKDKE+  + D  ++++ KEEIS+RFKA  DQLVLIFAGKILKD D+L Q G+
Sbjct: 22  IKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQLVLIFAGKILKDPDSLAQCGV 81

Query: 73  KDGLTVHLVIKTPQKAQDPAAATASSPST-PDPASAPSTTPASPATPAQPSTSGSASSDA 131
           +DGLTVHLVIK   +A       AS P+  P P S P  +   PA               
Sbjct: 82  RDGLTVHLVIKRQHRAMGNECPAASVPTQGPSPGSLPQPSSIYPA--------------- 126

Query: 132 GSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMS 191
                            +G P+ +  +L+G      L  LGL    F +    + RQ +S
Sbjct: 127 -----------------DGPPAFSLGLLTG------LSRLGLAYRGFPDQPSSLMRQHVS 163

Query: 192 NPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMEL 251
            PE ++Q++++P +  ++SN  L+R +++ NP MQQL++ NPEI H+LNNPE+MRQT+E 
Sbjct: 164 VPEFVTQLIDDPFIPGLLSNTGLVRQLVLDNPHMQQLIQHNPEIGHILNNPEIMRQTLEF 223

Query: 252 ARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPF-SSLA 310
            RNPAMMQEM+R+QDR LSNLESIPGGYN L  MYTDI +PM +A +EQFG NPF ++  
Sbjct: 224 LRNPAMMQEMIRSQDRVLSNLESIPGGYNVLCTMYTDIMDPMLNAVQEQFGGNPFATATT 283

Query: 311 GNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINA 370
            N+ +++SQP R EN +PLPNPW      +   G  G   G     Q  P + N F    
Sbjct: 284 DNATTTTSQPSRMENCDPLPNPW------TSTHGGSGSRQGRQDGDQDAPDIRNRF---- 333

Query: 371 ASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQN---PDFAAQMMVNV 427
                       +   LQQ+ ENPQ +       Y++     L+Q+   P    ++  + 
Sbjct: 334 ----PNFLGIIRLYDYLQQLHENPQSL-----GTYLQGTASALSQSQEPPPSVNRVPPSS 384

Query: 428 PLF----AGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTL--QT 481
           P      +G P  +E + ++      +   P  L   T     Q   Q   G  +    T
Sbjct: 385 PSSQEPGSGQPLPEESVAIK-----GRSSCPAFLRYPTENSTGQGGDQDGAGKSSTGHST 439

Query: 482 EAPGLVPSLGSFGISRTP-APSAGSNAGSTPEAP----TSSPATPATSSPTGASSAQ--Q 534
             P LV  LG    +R P AP + S   + P  P      SPA P +  P G + A   Q
Sbjct: 440 NLPDLVSGLGD-SANRVPFAPLSFSPTAAIPGIPEPPWLPSPAYPRSLRPDGMNPAPQLQ 498

Query: 535 QLMQQMIQLLAGSGNSQVQTPEVRFQQQLEQ 565
             +Q  + LL     +      ++  +Q+EQ
Sbjct: 499 DEIQPQLPLLMHLQAAMANPRALQALRQIEQ 529


>gi|145580580 ubiquilin-like [Homo sapiens]
          Length = 475

 Score =  187 bits (474), Expect = 3e-47
 Identities = 149/489 (30%), Positives = 222/489 (45%), Gaps = 90/489 (18%)

Query: 14  RVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIK 73
           RV VKT  ++++ ++ D  SV++FKE +   F+ Q DQLVL+F G +LKD DTL+Q GI 
Sbjct: 32  RVIVKTAGNQKDFMVADDISVRQFKEMLLAHFQCQMDQLVLVFMGCLLKDHDTLSQRGIM 91

Query: 74  DGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGS 133
           DG T++LVIK+ Q ++  A +    P T DP      T  + +   QP+    A  +   
Sbjct: 92  DGHTIYLVIKSKQGSRSLAHSFRDLP-TNDPCHRDRNTKGNSSRVHQPTGMNQAPVELAH 150

Query: 134 GSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNP 193
                         G  +P      L                              +S+P
Sbjct: 151 F------------VGSDAPKVHTQNLE-----------------------------VSHP 169

Query: 194 EMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHML-NNPELMRQTMELA 252
           E  +Q++ENP +Q ++SN + M   I  +   QQLM++NPE+S +L +N E++ QT+ELA
Sbjct: 170 ECKAQMLENPSIQRLLSNMEFMWQFISEHLDTQQLMQQNPEVSRLLLDNSEILLQTLELA 229

Query: 253 RNPAMMQEMMRNQDRALS-----------NLESIPGGYNALRRMYTDIQEPMFSAAREQF 301
           RN AM+QE+M+ Q  + +            LE++PGG NAL + Y DI + M ++ ++ F
Sbjct: 230 RNLAMIQEIMQIQQPSQNLEYPLNPQPYLGLETMPGGNNALGQNYADINDQMLNSMQDPF 289

Query: 302 GNNPFSSLAGNS--DSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVH 359
           G NPF++L      +   S P      +   +  +  P T     S G  +  +  +   
Sbjct: 290 GGNPFTALLAGQVLEQVQSSPPPPPPSQEQQDQLTQHPATRVIYNSSGGFSSNTSANDTL 349

Query: 360 PTVSNPFGINAASL---GSGMFNSPEMQA---------LLQQISE--------------- 392
             V++    N A +   G     +    A         L QQ+ E               
Sbjct: 350 NKVNHTSKANTAMISTKGQSHICATRQPAWIPALPSIELTQQLQEEYKDATVSLSSSRQT 409

Query: 393 ---NPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQ 449
              + QL     S+     MMQ L  NP  AAQ+M    LF   PQL EQ R QLP FLQ
Sbjct: 410 LKGDLQLSDEQSSSQITGGMMQLLMNNPYLAAQIM----LFTSMPQLSEQWRQQLPTFLQ 465

Query: 450 QMQNPESLS 458
           Q Q  + LS
Sbjct: 466 QTQISDLLS 474


>gi|38158015 mastermind-like 3 [Homo sapiens]
          Length = 1133

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 116/542 (21%), Positives = 192/542 (35%), Gaps = 122/542 (22%)

Query: 94  ATASSPSTPDPASAPSTTPA-SPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSP 152
           + AS+P+ P+PAS+P+     SP TP Q  T G A    G+G   +       G+  G  
Sbjct: 396 SVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPV 455

Query: 153 SATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLM---------------------- 190
           +  +S +S    +  + +     A  M+ +QQ Q+Q                        
Sbjct: 456 AVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWS 515

Query: 191 ------------------SNPEMLSQIM--ENPLVQDM--------MSNPDLMRHMIMAN 222
                             ++P M  Q    +NP+V  M        M+N     HM M N
Sbjct: 516 PLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMIN 575

Query: 223 PQMQQLMERNPEISHML----NNPELMRQTMELA-----------RNPAM-----MQEMM 262
            Q   L   +    H +    N   L     +L+           +NP M      Q+  
Sbjct: 576 QQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQ 635

Query: 263 RNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDSSSSQPLR 322
           + Q +     +  P    A R   ++ Q+ +    ++   N P +  A  S      P+ 
Sbjct: 636 QQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPV- 694

Query: 323 TENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPE 382
                 LP    P   +S  PGSGG  +G                  A+  G G   S  
Sbjct: 695 -----GLPRTTGPM-QSSVPPGSGGMVSG------------------ASPAGPGFLGSQP 730

Query: 383 MQALLQQ--ISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQL 440
             A+++Q  I +  QL++      ++R   Q   Q     A+            QLQ+  
Sbjct: 731 QAAIMKQMLIDQRAQLIEQQ-KQQFLREQRQQQQQQQQILAEQ-----------QLQQS- 777

Query: 441 RLQLP-VFLQQMQNPESLSILT----NPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGI 495
              LP   LQ  +NP  +  +     +P+ + A ++ Q  LQ+++T    +  + G  GI
Sbjct: 778 --HLPRQHLQPQRNPYPVQQVNQFQGSPQDI-AAVRSQAALQSMRTSRL-MAQNAGMMGI 833

Query: 496 SRTPAPSAGSNAGSTPEAPTSSPATPATSSP--TGASSAQQQLMQQMIQLLAGSGNSQVQ 553
             +  P   + A +  E   +  +T  TS P     S+   Q++Q   Q      ++Q Q
Sbjct: 834 GPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQ 893

Query: 554 TP 555
            P
Sbjct: 894 GP 895



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 11/122 (9%)

Query: 462 NPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATP 521
           NP +  A   +Q      Q   PG  P     G    PA    + + S P A  SS  +P
Sbjct: 405 NPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSP 464

Query: 522 ATSSPTGASSAQQ--QLMQQMIQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQ 579
           A      A+  QQ  +LMQQ           Q Q  + + QQQ +Q       N+ +N  
Sbjct: 465 AEQLKQMAAQQQQRAKLMQQ---------KQQQQQQQQQQQQQQQQQQQQQHSNQTSNWS 515

Query: 580 AL 581
            L
Sbjct: 516 PL 517



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 21/152 (13%)

Query: 434 PQLQEQLRLQLPVFLQQMQNPESLSILTNPRA------MQALLQIQQGLQTLQTEAPGLV 487
           P +Q+Q + Q     QQ Q       L  PRA       + LL  Q+G+   Q  A   +
Sbjct: 626 PYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMN-QPMAYAAL 684

Query: 488 PSLGS----FGISRTPAPSAGS-NAGSTPEAPTSSPATPAT--SSPTGASSAQ------- 533
           PS G      G+ RT  P   S   GS      +SPA P    S P  A   Q       
Sbjct: 685 PSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRA 744

Query: 534 QQLMQQMIQLLAGSGNSQVQTPEVRFQQQLEQ 565
           Q + QQ  Q L      Q Q  ++  +QQL+Q
Sbjct: 745 QLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ 776


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 108/517 (20%), Positives = 175/517 (33%), Gaps = 106/517 (20%)

Query: 83  KTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGG 142
           K+     DP  A  S   T  PA+  +     P  P Q  + G   S    G   S  G 
Sbjct: 73  KSQASVSDPMNALQSL--TGGPAAGAAGIGMPPRGPGQ--SLGGMGSLGAMGQPMSLSGQ 128

Query: 143 PSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMEN 202
           P PG    +P + A + +          L L      + QQQ Q Q      +  Q  + 
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQT----QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQ 184

Query: 203 PLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHML-----NNPELMRQTMELARNPAM 257
              Q       + +       Q QQL ++  +  H++     N  ++ +Q  +L R   +
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQL 244

Query: 258 MQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDSSS 317
             +  + Q +     +       AL+      Q PM     +Q    P  +L        
Sbjct: 245 QLQQQQQQQQQQQQQQQ-----QALQAQPPIQQPPM-----QQPQPPPSQALP----QQL 290

Query: 318 SQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGM 377
            Q   T++ +P P P  P       P +  + +     SQ  P VS       A  G  +
Sbjct: 291 QQMHHTQHHQPPPQPQQP-------PVAQNQPSQLPPQSQTQPLVSQA----QALPGQML 339

Query: 378 FNSPEMQ-----ALLQQISENPQLMQNVIS----------APYMRSMMQTLAQN------ 416
           +  P ++      ++QQ    PQ+ Q   +          AP ++ + + LAQ       
Sbjct: 340 YTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRA 399

Query: 417 ---PDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFL-----QQMQNPESLSILTNPRAMQA 468
              P  A   + +  +  G   + +  +  LP+       QQ+Q P+S+     P     
Sbjct: 400 RFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP----- 454

Query: 469 LLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT----- 523
                       +  PG   S  +  +S  PAPS  S   S    P+ SP T  T     
Sbjct: 455 ------------SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 502

Query: 524 ----------------SSPTGASSA-QQQLMQQMIQL 543
                            SP G+S A +QQ + ++ QL
Sbjct: 503 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQL 539



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 12/97 (12%)

Query: 485 GLVPSLGSFG--ISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQ 542
           G + SLG+ G  +S +  P  G++  +       S ATP T       + QQQ  QQ  Q
Sbjct: 111 GGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQ 170

Query: 543 LLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQ 579
                     Q  +   QQQ +Q     F  +++ +Q
Sbjct: 171 ----------QQQQAALQQQQQQQQQQQFQAQQSAMQ 197


>gi|4826964 UV excision repair protein RAD23 homolog A [Homo
           sapiens]
          Length = 363

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/252 (23%), Positives = 108/252 (42%), Gaps = 38/252 (15%)

Query: 54  LIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPAS-----AP 108
           LI+AGKIL D   +  + I +   V +++   +  Q  +A   +SP+    +S     AP
Sbjct: 48  LIYAGKILSDDVPIRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAP 107

Query: 109 STTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSG------F 162
           ++  + P   A+   S S  S   +     SG  PS G+      A +++++G       
Sbjct: 108 TSGMSHPPPAAREDKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETML 167

Query: 163 GGILGLG--------SLGLGSANFMELQQQMQRQLMSNPE------MLSQIMENPLVQDM 208
             I+ +G        +L     N     + +   +  +PE        SQ+ E P  +  
Sbjct: 168 TEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAA 227

Query: 209 MSNPDLMRHMIMANPQ---MQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQ 265
             NP      +   PQ   M+Q++++NP +      P L++Q  +   NP ++Q++ R+Q
Sbjct: 228 GENP---LEFLRDQPQFQNMRQVIQQNPALL-----PALLQQLGQ--ENPQLLQQISRHQ 277

Query: 266 DRALSNLESIPG 277
           ++ +  L   PG
Sbjct: 278 EQFIQMLNEPPG 289



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 13/138 (9%)

Query: 459 ILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSP 518
           ++T  +A Q      +   T   E+    P   + G+S  P  +    + S   APT+SP
Sbjct: 75  MVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSP 134

Query: 519 ATPATSSPTGASSAQQQLMQQMIQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANL 578
            + + S P+  SS +++       L+ GS           ++  L ++ SMG+  RE  +
Sbjct: 135 ESVSGSVPSSGSSGREE--DAASTLVTGS----------EYETMLTEIMSMGY-ERERVV 181

Query: 579 QALIATGGDINAAIERLL 596
            AL A+  + + A+E LL
Sbjct: 182 AALRASYNNPHRAVEYLL 199



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 4/81 (4%)

Query: 374 GSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN 433
           GS   +    Q   +   ENP  ++ +   P  ++M Q + QNP     ++    L   N
Sbjct: 211 GSVQESQVSEQPATEAAGENP--LEFLRDQPQFQNMRQVIQQNPALLPALLQQ--LGQEN 266

Query: 434 PQLQEQLRLQLPVFLQQMQNP 454
           PQL +Q+      F+Q +  P
Sbjct: 267 PQLLQQISRHQEQFIQMLNEP 287


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 110/494 (22%), Positives = 166/494 (33%), Gaps = 100/494 (20%)

Query: 83  KTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGG 142
           K+     DP  A  S   T  PA+  +     P  P Q  + G   S    G   S  G 
Sbjct: 73  KSQASVSDPMNALQSL--TGGPAAGAAGIGMPPRGPGQ--SLGGMGSLGAMGQPMSLSGQ 128

Query: 143 PSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMEN 202
           P PG    +P + A + +          L L      + QQQ Q Q      +  Q  + 
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQT----QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQ 184

Query: 203 PLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHML-----NNPELMRQTMELARNPAM 257
              Q       + +       Q QQL ++  +  H++     N  ++ +Q  +L R   +
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQL 244

Query: 258 MQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDSSS 317
             +  + Q +     +       AL+      Q PM     +Q    P  +L        
Sbjct: 245 QLQQQQQQQQQQQQQQQ-----QALQAQPPIQQPPM-----QQPQPPPSQALP----QQL 290

Query: 318 SQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGM 377
            Q   T++ +P P P  P       P +  + +     SQ  P VS       A  G  +
Sbjct: 291 QQMHHTQHHQPPPQPQQP-------PVAQNQPSQLPPQSQTQPLVSQA----QALPGQML 339

Query: 378 FNSPEMQ-----ALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAG 432
           +  P ++      ++QQ    PQ+ Q            QT  Q    AAQM+       G
Sbjct: 340 YTQPPLKFVRAPMVVQQPPVQPQVQQQ-----------QTAVQTAQ-AAQMVA-----PG 382

Query: 433 NPQLQEQL-RLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLG 491
               Q  L  L  P   QQ+Q P+S+     P                 +  PG   S  
Sbjct: 383 VQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP-----------------SPQPGQPSSQP 425

Query: 492 SFGISRTPAPSAGSNAGSTPEAPTSSPATPAT---------------------SSPTGAS 530
           +  +S  PAPS  S   S    P+ SP T  T                      SP G+S
Sbjct: 426 NSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSS 485

Query: 531 SA-QQQLMQQMIQL 543
            A +QQ + ++ QL
Sbjct: 486 QAEEQQYLDKLKQL 499



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 12/97 (12%)

Query: 485 GLVPSLGSFG--ISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQ 542
           G + SLG+ G  +S +  P  G++  +       S ATP T       + QQQ  QQ  Q
Sbjct: 111 GGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQ 170

Query: 543 LLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQ 579
                     Q  +   QQQ +Q     F  +++ +Q
Sbjct: 171 ----------QQQQAALQQQQQQQQQQQFQAQQSAMQ 197


>gi|4506387 UV excision repair protein RAD23 homolog B [Homo
           sapiens]
          Length = 409

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 89/371 (23%), Positives = 147/371 (39%), Gaps = 53/371 (14%)

Query: 13  IRVTVKTPKDKE-EIVICDRASVKEFKEEISRRFKAQQDQLV---LIFAGKILKDGDTLN 68
           ++VT+KT + +  +I I    +VK  KE+I          +    LI+AGKIL D   L 
Sbjct: 1   MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALK 60

Query: 69  QHGIKDGLTVHLVIKTPQKAQDPAAATA--SSPS-----------------TPDPASAPS 109
           ++ I +   V +++  P+    PA AT   S+P+                 TP PA AP+
Sbjct: 61  EYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPT 120

Query: 110 TTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLG 169
           +TPAS  TPA  +T+ S  + A +  +      P+      SP+AT S  SG      L 
Sbjct: 121 STPAS-ITPAS-ATASSEPAPASAAKQEKPAEKPAETPVATSPTATDS-TSGDSSRSNLF 177

Query: 170 SLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPD-LMRHMIMANP-QMQQ 227
                +    +  + M  ++MS      Q++    ++   +NPD  + +++M  P   + 
Sbjct: 178 EDATSALVTGQSYENMVTEIMSMGYEREQVI--AALRASFNNPDRAVEYLLMGIPGDRES 235

Query: 228 LMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGY--NALRRM 285
               +P  +     P+        A   A             +   +  GG+    LR  
Sbjct: 236 QAVVDPPQAASTGAPQSSAVAAAAATTTA-------------TTTTTSSGGHPLEFLR-- 280

Query: 286 YTDIQEPMFSAAREQFGNNP--FSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP 343
                +P F   R+    NP    +L       + Q L+  ++         + P  +A 
Sbjct: 281 ----NQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAG 336

Query: 344 GSGGEGTGGSG 354
           G GG G GGSG
Sbjct: 337 GQGGGGGGGSG 347


>gi|41152107 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 15/100 (15%)

Query: 496 SRTPAPSA-GSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQ-LLAGSGNSQVQ 553
           S TP P   G ++G++P +      TP T+           L  Q +Q  L  SG   +Q
Sbjct: 286 SHTPTPGTQGHSSGTSPMSSGVQSGTPITND----------LFSQALQHALQASGQPSLQ 335

Query: 554 TPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIE 593
           +   ++Q QL+QL  MG  + E +L+AL ATGGDI AA+E
Sbjct: 336 S---QWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 18/39 (46%), Positives = 27/39 (69%), Gaps = 1/39 (2%)

Query: 54  LIFAGKILKDGDTLNQHGIKDGLTVHLVIKT-PQKAQDP 91
           LI+ G+ LKD  TL+ +GI+ G TVH++ K+ P+  Q P
Sbjct: 63  LIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKP 101



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 95  TASSPSTPDPASAPSTTPASPATPAQPST-SGSASSDAGSGSRRSSGGGPSPGAGEGSPS 153
           T S+PS+  P+S P++   S A   +P T S  A++ A + +  SS   P+PG  +G  S
Sbjct: 240 TRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGT-QGHSS 298

Query: 154 ATASILSG 161
            T+ + SG
Sbjct: 299 GTSPMSSG 306


>gi|14249682 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 15/100 (15%)

Query: 496 SRTPAPSA-GSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQ-LLAGSGNSQVQ 553
           S TP P   G ++G++P +      TP T+           L  Q +Q  L  SG   +Q
Sbjct: 286 SHTPTPGTQGHSSGTSPMSSGVQSGTPITND----------LFSQALQHALQASGQPSLQ 335

Query: 554 TPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIE 593
           +   ++Q QL+QL  MG  + E +L+AL ATGGDI AA+E
Sbjct: 336 S---QWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 18/39 (46%), Positives = 27/39 (69%), Gaps = 1/39 (2%)

Query: 54  LIFAGKILKDGDTLNQHGIKDGLTVHLVIKT-PQKAQDP 91
           LI+ G+ LKD  TL+ +GI+ G TVH++ K+ P+  Q P
Sbjct: 63  LIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKP 101



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 95  TASSPSTPDPASAPSTTPASPATPAQPST-SGSASSDAGSGSRRSSGGGPSPGAGEGSPS 153
           T S+PS+  P+S P++   S A   +P T S  A++ A + +  SS   P+PG  +G  S
Sbjct: 240 TRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGT-QGHSS 298

Query: 154 ATASILSG 161
            T+ + SG
Sbjct: 299 GTSPMSSG 306


>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/266 (22%), Positives = 108/266 (40%), Gaps = 46/266 (17%)

Query: 5   SGAETRPPIRVTVKT-PKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKD 63
           +  E    + V VKT        ++  + +VKEFKE I+       ++  LI+ G++L+D
Sbjct: 9   TAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQD 68

Query: 64  GDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPST 123
              L ++ +  G  +HLV + P             P T  P+ A S T            
Sbjct: 69  DKKLQEYNV-GGKVIHLVERAP-------------PQTHLPSGASSGT------------ 102

Query: 124 SGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQ 183
            GSAS+  G GS   + G   PGA     +A + ++ G   +   GS        +++  
Sbjct: 103 -GSASATHGGGSPPGTRG---PGASVHDRNANSYVMVGTFNLPSDGSA-------VDVHI 151

Query: 184 QMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPE 243
            M++  + +   +  +M   +++D+ +    M       PQ  Q   + P ++     PE
Sbjct: 152 NMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVT-----PE 206

Query: 244 ---LMRQTMELARNPAMMQEMMRNQD 266
              L  QT E   + A  +E M  ++
Sbjct: 207 PVALSSQTSEPVESEAPPREPMEAEE 232



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 34/189 (17%)

Query: 323 TENREPLPNPWSPSPP-----TSQAPG--SGGEGT-GGSGTSQVHP-----TVSNPFGIN 369
           T+   P P P  P PP     T   PG  SGG G+ GG G   + P      V       
Sbjct: 647 TQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 706

Query: 370 AASLGSGMFNSPEMQALLQQISENPQLMQNVISAP--YMRSMMQTLAQNPDFAAQMMVNV 427
             SLG+   +S  + A +Q++S +  + +        +  +++  L QN      M+  V
Sbjct: 707 LGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQN----FSMVDVV 762

Query: 428 PLFAGNPQLQEQLRLQLPVFLQ------QMQNPESLSILTNP---------RAMQALLQI 472
            L  G+ Q  ++L+ QL  F        Q   P ++ + T+          R   +L+Q+
Sbjct: 763 MLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQV 822

Query: 473 QQGLQTLQT 481
           Q G+  ++T
Sbjct: 823 QPGVDIIRT 831



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 468 ALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPS-AGSNAGSTPEAPTSSPAT--PATS 524
           +L Q+  GL       P LV   G+ G++  PAP+ A ++AG+T  A T+ PA   PA  
Sbjct: 530 SLAQMVSGLVGQLLMQPVLVAQ-GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588

Query: 525 SPT-GASSAQQQLMQQMIQLLA----GSGNSQVQTPEV 557
            PT   S A  Q  Q +  LL     G+G S V +P +
Sbjct: 589 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTI 626



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 44/223 (19%)

Query: 329 LPNPWSPSPPTSQAPGSGGE--GTGGSGTSQVHPTVSNPFGINAASLGSGMFNSP----- 381
           LP+  S    ++ A   GG   GT G G S VH   +N + +       G FN P     
Sbjct: 94  LPSGASSGTGSASATHGGGSPPGTRGPGAS-VHDRNANSYVM------VGTFNLPSDGSA 146

Query: 382 -EMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQL 440
            ++   ++Q     +    ++ A +M   +QTL    +             G PQ Q   
Sbjct: 147 VDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECR-----------GGPQPQHS- 194

Query: 441 RLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPA 500
             Q P        P+  ++   P A+ +     Q  + +++EAP   P        R PA
Sbjct: 195 --QPP--------PQPPAVTPEPVALSS-----QTSEPVESEAPPREPMEAEEVEERAPA 239

Query: 501 PSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQL 543
            +     G  P  PT +P T A + P+ A     +++Q++ +L
Sbjct: 240 QNPELTPGPAPAGPTPAPETNAPNHPSPAEYV--EVLQELQRL 280



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 5/79 (6%)

Query: 84  TPQKAQDPAAATASSPS----TPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSS 139
           TP  A  PA ATAS+ +    T   A      PA P    QPS +    S    G+    
Sbjct: 553 TPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQL-LGNLLGP 611

Query: 140 GGGPSPGAGEGSPSATASI 158
            G  + G+G  SP+ T ++
Sbjct: 612 AGPGAGGSGVASPTITVAM 630


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/266 (22%), Positives = 108/266 (40%), Gaps = 46/266 (17%)

Query: 5   SGAETRPPIRVTVKT-PKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKD 63
           +  E    + V VKT        ++  + +VKEFKE I+       ++  LI+ G++L+D
Sbjct: 9   TAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQD 68

Query: 64  GDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPST 123
              L ++ +  G  +HLV + P             P T  P+ A S T            
Sbjct: 69  DKKLQEYNV-GGKVIHLVERAP-------------PQTHLPSGASSGT------------ 102

Query: 124 SGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQ 183
            GSAS+  G GS   + G   PGA     +A + ++ G   +   GS        +++  
Sbjct: 103 -GSASATHGGGSPPGTRG---PGASVHDRNANSYVMVGTFNLPSDGSA-------VDVHI 151

Query: 184 QMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPE 243
            M++  + +   +  +M   +++D+ +    M       PQ  Q   + P ++     PE
Sbjct: 152 NMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVT-----PE 206

Query: 244 ---LMRQTMELARNPAMMQEMMRNQD 266
              L  QT E   + A  +E M  ++
Sbjct: 207 PVALSSQTSEPVESEAPPREPMEAEE 232



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 34/189 (17%)

Query: 323 TENREPLPNPWSPSPP-----TSQAPG--SGGEGT-GGSGTSQVHP-----TVSNPFGIN 369
           T+   P P P  P PP     T   PG  SGG G+ GG G   + P      V       
Sbjct: 647 TQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 706

Query: 370 AASLGSGMFNSPEMQALLQQISENPQLMQNVISAP--YMRSMMQTLAQNPDFAAQMMVNV 427
             SLG+   +S  + A +Q++S +  + +        +  +++  L QN      M+  V
Sbjct: 707 LGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQN----FSMVDVV 762

Query: 428 PLFAGNPQLQEQLRLQLPVFLQ------QMQNPESLSILTNP---------RAMQALLQI 472
            L  G+ Q  ++L+ QL  F        Q   P ++ + T+          R   +L+Q+
Sbjct: 763 MLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQV 822

Query: 473 QQGLQTLQT 481
           Q G+  ++T
Sbjct: 823 QPGVDIIRT 831



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 468 ALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPS-AGSNAGSTPEAPTSSPAT--PATS 524
           +L Q+  GL       P LV   G+ G++  PAP+ A ++AG+T  A T+ PA   PA  
Sbjct: 530 SLAQMVSGLVGQLLMQPVLVAQ-GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588

Query: 525 SPT-GASSAQQQLMQQMIQLLA----GSGNSQVQTPEV 557
            PT   S A  Q  Q +  LL     G+G S V +P +
Sbjct: 589 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTI 626



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 44/223 (19%)

Query: 329 LPNPWSPSPPTSQAPGSGGE--GTGGSGTSQVHPTVSNPFGINAASLGSGMFNSP----- 381
           LP+  S    ++ A   GG   GT G G S VH   +N + +       G FN P     
Sbjct: 94  LPSGASSGTGSASATHGGGSPPGTRGPGAS-VHDRNANSYVM------VGTFNLPSDGSA 146

Query: 382 -EMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQL 440
            ++   ++Q     +    ++ A +M   +QTL    +             G PQ Q   
Sbjct: 147 VDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECR-----------GGPQPQHS- 194

Query: 441 RLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPA 500
             Q P        P+  ++   P A+ +     Q  + +++EAP   P        R PA
Sbjct: 195 --QPP--------PQPPAVTPEPVALSS-----QTSEPVESEAPPREPMEAEEVEERAPA 239

Query: 501 PSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQL 543
            +     G  P  PT +P T A + P+ A     +++Q++ +L
Sbjct: 240 QNPELTPGPAPAGPTPAPETNAPNHPSPAEYV--EVLQELQRL 280



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 5/79 (6%)

Query: 84  TPQKAQDPAAATASSPS----TPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSS 139
           TP  A  PA ATAS+ +    T   A      PA P    QPS +    S    G+    
Sbjct: 553 TPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQL-LGNLLGP 611

Query: 140 GGGPSPGAGEGSPSATASI 158
            G  + G+G  SP+ T ++
Sbjct: 612 AGPGAGGSGVASPTITVAM 630


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/266 (22%), Positives = 108/266 (40%), Gaps = 46/266 (17%)

Query: 5   SGAETRPPIRVTVKT-PKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKD 63
           +  E    + V VKT        ++  + +VKEFKE I+       ++  LI+ G++L+D
Sbjct: 9   TAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQD 68

Query: 64  GDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPST 123
              L ++ +  G  +HLV + P             P T  P+ A S T            
Sbjct: 69  DKKLQEYNV-GGKVIHLVERAP-------------PQTHLPSGASSGT------------ 102

Query: 124 SGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQ 183
            GSAS+  G GS   + G   PGA     +A + ++ G   +   GS        +++  
Sbjct: 103 -GSASATHGGGSPPGTRG---PGASVHDRNANSYVMVGTFNLPSDGSA-------VDVHI 151

Query: 184 QMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPE 243
            M++  + +   +  +M   +++D+ +    M       PQ  Q   + P ++     PE
Sbjct: 152 NMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVT-----PE 206

Query: 244 ---LMRQTMELARNPAMMQEMMRNQD 266
              L  QT E   + A  +E M  ++
Sbjct: 207 PVALSSQTSEPVESEAPPREPMEAEE 232



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 34/189 (17%)

Query: 323 TENREPLPNPWSPSPP-----TSQAPG--SGGEGT-GGSGTSQVHP-----TVSNPFGIN 369
           T+   P P P  P PP     T   PG  SGG G+ GG G   + P      V       
Sbjct: 647 TQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 706

Query: 370 AASLGSGMFNSPEMQALLQQISENPQLMQNVISAP--YMRSMMQTLAQNPDFAAQMMVNV 427
             SLG+   +S  + A +Q++S +  + +        +  +++  L QN      M+  V
Sbjct: 707 LGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQN----FSMVDVV 762

Query: 428 PLFAGNPQLQEQLRLQLPVFLQ------QMQNPESLSILTNP---------RAMQALLQI 472
            L  G+ Q  ++L+ QL  F        Q   P ++ + T+          R   +L+Q+
Sbjct: 763 MLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQV 822

Query: 473 QQGLQTLQT 481
           Q G+  ++T
Sbjct: 823 QPGVDIIRT 831



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 468 ALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPS-AGSNAGSTPEAPTSSPAT--PATS 524
           +L Q+  GL       P LV   G+ G++  PAP+ A ++AG+T  A T+ PA   PA  
Sbjct: 530 SLAQMVSGLVGQLLMQPVLVAQ-GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588

Query: 525 SPT-GASSAQQQLMQQMIQLLA----GSGNSQVQTPEV 557
            PT   S A  Q  Q +  LL     G+G S V +P +
Sbjct: 589 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTI 626



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 44/223 (19%)

Query: 329 LPNPWSPSPPTSQAPGSGGE--GTGGSGTSQVHPTVSNPFGINAASLGSGMFNSP----- 381
           LP+  S    ++ A   GG   GT G G S VH   +N + +       G FN P     
Sbjct: 94  LPSGASSGTGSASATHGGGSPPGTRGPGAS-VHDRNANSYVM------VGTFNLPSDGSA 146

Query: 382 -EMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQL 440
            ++   ++Q     +    ++ A +M   +QTL    +             G PQ Q   
Sbjct: 147 VDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECR-----------GGPQPQHS- 194

Query: 441 RLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPA 500
             Q P        P+  ++   P A+ +     Q  + +++EAP   P        R PA
Sbjct: 195 --QPP--------PQPPAVTPEPVALSS-----QTSEPVESEAPPREPMEAEEVEERAPA 239

Query: 501 PSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQL 543
            +     G  P  PT +P T A + P+ A     +++Q++ +L
Sbjct: 240 QNPELTPGPAPAGPTPAPETNAPNHPSPAEYV--EVLQELQRL 280



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 5/79 (6%)

Query: 84  TPQKAQDPAAATASSPS----TPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSS 139
           TP  A  PA ATAS+ +    T   A      PA P    QPS +    S    G+    
Sbjct: 553 TPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQL-LGNLLGP 611

Query: 140 GGGPSPGAGEGSPSATASI 158
            G  + G+G  SP+ T ++
Sbjct: 612 AGPGAGGSGVASPTITVAM 630


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 120/534 (22%), Positives = 178/534 (33%), Gaps = 85/534 (15%)

Query: 85  PQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRS----SG 140
           P ++  P  A A + S+P   +  S   A+  +   PS+S SASS + S +++      G
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276

Query: 141 GGPSPGAGEGSPSATA-----------SILSGFGGILG--------LGSLGLGSANFME- 180
           GGPS  AG G+P  TA           S   G+ G  G         G  G G A+    
Sbjct: 277 GGPS-AAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQ 335

Query: 181 -----------------LQQQMQRQLMSNPEM---LSQIMENPLVQDMMSNPDLMRHMIM 220
                             QQ+     MS          +   P     M     MR    
Sbjct: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395

Query: 221 --ANP-QMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLESI-- 275
              NP   QQ     P+  H         QT +  R P  MQ   ++    LS  + I  
Sbjct: 396 GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQ--RYPMTMQGRAQSAMGGLSYTQQIPP 453

Query: 276 -----PGGYNAL-RRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDS----SSSQPLRTEN 325
                P GY    +  Y + Q P     +  +   P S       S      SQP + ++
Sbjct: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513

Query: 326 REPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQA 385
            +P  +     PP  Q+P           T+Q HP    P+    A        SP  Q 
Sbjct: 514 SQPPYSQQPSQPPHQQSP---APYPSQQSTTQQHPQSQPPYSQPQA-------QSPYQQQ 563

Query: 386 LLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLP 445
             QQ + +    Q     P  +   QT      F     ++   F         +     
Sbjct: 564 QPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSS-- 621

Query: 446 VFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGS 505
              +  Q   +LS+ + P ++  L      L  + TE   L P + + GIS +      S
Sbjct: 622 ---KGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEG-ALSPGVSTSGISSSQGEQ--S 674

Query: 506 NAGSTPEAPTSSPATPA----TSSPTGASSAQQQLMQQMIQLLAGSGNSQVQTP 555
           N   +P +P +SP  P     + SP G+ ++  Q     +   A  GN     P
Sbjct: 675 NPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRP 728



 Score = 32.7 bits (73), Expect = 0.98
 Identities = 48/231 (20%), Positives = 73/231 (31%), Gaps = 9/231 (3%)

Query: 176 ANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNP---DLMRHMIMANPQMQQLMERN 232
           A +   Q   Q+   S P       ++P  Q     P    L +      PQ QQ  +  
Sbjct: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591

Query: 233 PEISHMLNNPELMRQTM--ELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQ 290
                     EL + +   + +  P+M       +D  LS L+S P     L     D+ 
Sbjct: 592 YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLP 650

Query: 291 EPMFSAAREQFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGT 350
                A       +  SS  G   + +  P        LP    PSP    +P S  +  
Sbjct: 651 MGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSR 710

Query: 351 GGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQ---ISENPQLMQ 398
            G  +    P    P    +    S M  S    ++ Q    +  NPQ+ Q
Sbjct: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 12/102 (11%)

Query: 86  QKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPS----TSGSASSDAGSGSRRSSGG 141
           ++A   AAA A++      A+A   +      P QP       G+ S+  G G    SGG
Sbjct: 33  EEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGG 92

Query: 142 GP--------SPGAGEGSPSATASILSGFGGILGLGSLGLGS 175
           GP        S G     P+   ++    GG  G  S G+G+
Sbjct: 93  GPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 120/534 (22%), Positives = 178/534 (33%), Gaps = 85/534 (15%)

Query: 85  PQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRS----SG 140
           P ++  P  A A + S+P   +  S   A+  +   PS+S SASS + S +++      G
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276

Query: 141 GGPSPGAGEGSPSATA-----------SILSGFGGILG--------LGSLGLGSANFME- 180
           GGPS  AG G+P  TA           S   G+ G  G         G  G G A+    
Sbjct: 277 GGPS-AAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQ 335

Query: 181 -----------------LQQQMQRQLMSNPEM---LSQIMENPLVQDMMSNPDLMRHMIM 220
                             QQ+     MS          +   P     M     MR    
Sbjct: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395

Query: 221 --ANP-QMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLESI-- 275
              NP   QQ     P+  H         QT +  R P  MQ   ++    LS  + I  
Sbjct: 396 GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQ--RYPMTMQGRAQSAMGGLSYTQQIPP 453

Query: 276 -----PGGYNAL-RRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDS----SSSQPLRTEN 325
                P GY    +  Y + Q P     +  +   P S       S      SQP + ++
Sbjct: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513

Query: 326 REPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQA 385
            +P  +     PP  Q+P           T+Q HP    P+    A        SP  Q 
Sbjct: 514 SQPPYSQQPSQPPHQQSP---APYPSQQSTTQQHPQSQPPYSQPQA-------QSPYQQQ 563

Query: 386 LLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLP 445
             QQ + +    Q     P  +   QT      F     ++   F         +     
Sbjct: 564 QPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSS-- 621

Query: 446 VFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGS 505
              +  Q   +LS+ + P ++  L      L  + TE   L P + + GIS +      S
Sbjct: 622 ---KGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEG-ALSPGVSTSGISSSQGEQ--S 674

Query: 506 NAGSTPEAPTSSPATPA----TSSPTGASSAQQQLMQQMIQLLAGSGNSQVQTP 555
           N   +P +P +SP  P     + SP G+ ++  Q     +   A  GN     P
Sbjct: 675 NPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRP 728



 Score = 32.7 bits (73), Expect = 0.98
 Identities = 48/231 (20%), Positives = 73/231 (31%), Gaps = 9/231 (3%)

Query: 176 ANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNP---DLMRHMIMANPQMQQLMERN 232
           A +   Q   Q+   S P       ++P  Q     P    L +      PQ QQ  +  
Sbjct: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591

Query: 233 PEISHMLNNPELMRQTM--ELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQ 290
                     EL + +   + +  P+M       +D  LS L+S P     L     D+ 
Sbjct: 592 YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLP 650

Query: 291 EPMFSAAREQFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGT 350
                A       +  SS  G   + +  P        LP    PSP    +P S  +  
Sbjct: 651 MGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSR 710

Query: 351 GGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQ---ISENPQLMQ 398
            G  +    P    P    +    S M  S    ++ Q    +  NPQ+ Q
Sbjct: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 12/102 (11%)

Query: 86  QKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPS----TSGSASSDAGSGSRRSSGG 141
           ++A   AAA A++      A+A   +      P QP       G+ S+  G G    SGG
Sbjct: 33  EEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGG 92

Query: 142 GP--------SPGAGEGSPSATASILSGFGGILGLGSLGLGS 175
           GP        S G     P+   ++    GG  G  S G+G+
Sbjct: 93  GPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 58/267 (21%), Positives = 109/267 (40%), Gaps = 42/267 (15%)

Query: 5   SGAETRPPIRVTVKT-PKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKD 63
           +  E    + V VKT        ++  + +VKEFKE I+       ++  LI+ G++L+D
Sbjct: 9   TAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQD 68

Query: 64  GDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPST 123
              L ++ +  G  +HLV + P             P T  P+ A S T            
Sbjct: 69  DKKLQEYNV-GGKVIHLVERAP-------------PQTHLPSGASSGT------------ 102

Query: 124 SGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQ 183
            GSAS+  G GS   + G   PGA     +A + ++ G   +   GS        +++  
Sbjct: 103 -GSASATHGGGSPPGTRG---PGASVHDRNANSYVMVGTFNLPSDGSA-------VDVHI 151

Query: 184 QMQRQLMSNPEMLSQIMENPLVQD---MMSNPDLMRHMIMANPQMQQLMERNPEISHMLN 240
            M++  + +   +  +M   +++D   ++S  + + ++        Q  +  P+   +  
Sbjct: 152 NMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMETLPYLQCRGGPQPQHSQPPPQPPAVTP 211

Query: 241 NP-ELMRQTMELARNPAMMQEMMRNQD 266
            P  L  QT E   + A  +E M  ++
Sbjct: 212 EPVALSSQTSEPVESEAPPREPMEAEE 238



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 34/189 (17%)

Query: 323 TENREPLPNPWSPSPP-----TSQAPG--SGGEGT-GGSGTSQVHP-----TVSNPFGIN 369
           T+   P P P  P PP     T   PG  SGG G+ GG G   + P      V       
Sbjct: 653 TQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 712

Query: 370 AASLGSGMFNSPEMQALLQQISENPQLMQNVISAP--YMRSMMQTLAQNPDFAAQMMVNV 427
             SLG+   +S  + A +Q++S +  + +        +  +++  L QN      M+  V
Sbjct: 713 LGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQN----FSMVDVV 768

Query: 428 PLFAGNPQLQEQLRLQLPVFLQ------QMQNPESLSILTNP---------RAMQALLQI 472
            L  G+ Q  ++L+ QL  F        Q   P ++ + T+          R   +L+Q+
Sbjct: 769 MLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQV 828

Query: 473 QQGLQTLQT 481
           Q G+  ++T
Sbjct: 829 QPGVDIIRT 837



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 52/223 (23%), Positives = 88/223 (39%), Gaps = 38/223 (17%)

Query: 329 LPNPWSPSPPTSQAPGSGGE--GTGGSGTSQVHPTVSNPFGINAASLGSGMFNSP----- 381
           LP+  S    ++ A   GG   GT G G S VH   +N + +       G FN P     
Sbjct: 94  LPSGASSGTGSASATHGGGSPPGTRGPGAS-VHDRNANSYVM------VGTFNLPSDGSA 146

Query: 382 -EMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQL 440
            ++   ++Q     +    ++ A +M   +QTL    +    +        G PQ Q   
Sbjct: 147 VDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMETLPYLQCR-----GGPQPQHS- 200

Query: 441 RLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPA 500
             Q P        P+  ++   P A+ +     Q  + +++EAP   P        R PA
Sbjct: 201 --QPP--------PQPPAVTPEPVALSS-----QTSEPVESEAPPREPMEAEEVEERAPA 245

Query: 501 PSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQL 543
            +     G  P  PT +P T A + P+ A     +++Q++ +L
Sbjct: 246 QNPELTPGPAPAGPTPAPETNAPNHPSPAEYV--EVLQELQRL 286



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 468 ALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPS-AGSNAGSTPEAPTSSPAT--PATS 524
           +L Q+  GL       P LV   G+ G++  PAP+ A ++AG+T  A T+ PA   PA  
Sbjct: 536 SLAQMVSGLVGQLLMQPVLVAQ-GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 594

Query: 525 SPT-GASSAQQQLMQQMIQLLA----GSGNSQVQTPEV 557
            PT   S A  Q  Q +  LL     G+G S V +P +
Sbjct: 595 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTI 632



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 5/79 (6%)

Query: 84  TPQKAQDPAAATASSPS----TPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSS 139
           TP  A  PA ATAS+ +    T   A      PA P    QPS +    S    G+    
Sbjct: 559 TPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQL-LGNLLGP 617

Query: 140 GGGPSPGAGEGSPSATASI 158
            G  + G+G  SP+ T ++
Sbjct: 618 AGPGAGGSGVASPTITVAM 636


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 121/572 (21%), Positives = 188/572 (32%), Gaps = 92/572 (16%)

Query: 41   ISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPS 100
            I ++ + QQ Q  L  A  + +   ++ + G+  G    L   TP     P     ++P 
Sbjct: 1809 IKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVV-GQQQGLPSPTPATPTTPTGQQPTTPQ 1867

Query: 101  TPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILS 160
            TP P S P  TP +   P  P T  +     G  + + +   P   A    P    + + 
Sbjct: 1868 TPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVE 1927

Query: 161  GFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIM 220
                I          A+    Q+ +Q Q+     M    M  P    M   P       M
Sbjct: 1928 MAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPP---PMTRGPSGHLEPGM 1984

Query: 221  ANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQ-----------DRAL 269
                MQQ   + P     L  P+ ++  M     PAMM      Q              +
Sbjct: 1985 GPTGMQQ---QPPWSQGGLPQPQQLQSGMP---RPAMMSVAQHGQPLNMAPQPGLGQVGI 2038

Query: 270  SNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDSSSS----QPLRTEN 325
            S L+       AL+ +   ++ P     ++Q      S L  N    ++    +  +  N
Sbjct: 2039 SPLKPGTVSQQALQNLLRTLRSPSSPLQQQQV----LSILHANPQLLAAFIKQRAAKYAN 2094

Query: 326  REPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFN------ 379
              P P P  P  P  Q PG       G      +P + N   + A    +G+        
Sbjct: 2095 SNPQPIPGQPGMPQGQ-PGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQ 2153

Query: 380  --------SPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQM----MVNV 427
                    SP+ Q +    +  P   ++++    M    Q     P     M        
Sbjct: 2154 LQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQ 2213

Query: 428  PLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAM------------QALLQIQQG 475
            P   G P  Q+Q   ++   +QQMQ      I   P+A+            Q LLQ Q G
Sbjct: 2214 PQGVGYPPQQQQ---RMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMG 2270

Query: 476  -------------LQTLQTEAPGL----VPSLGSFGISRTPAPSAGSNAGSTPEAPTSSP 518
                         +   Q ++P L    +P+  S  + R+P P       S P   + SP
Sbjct: 2271 SPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQV-RSPQPVPSPRPQSQPPHSSPSP 2329

Query: 519  ----------ATPATSSP-TGASSAQQQLMQQ 539
                       +P TSSP  G  +AQ   M+Q
Sbjct: 2330 RMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQ 2361



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 81/346 (23%), Positives = 124/346 (35%), Gaps = 50/346 (14%)

Query: 86   QKAQDPAAATASSPSTP-DPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPS 144
            Q+A      T  SPS+P       S   A+P   A       A+  A S  +   G    
Sbjct: 2048 QQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAA-FIKQRAAKYANSNPQPIPG---Q 2103

Query: 145  PGAGEGSPSATASILSGFGGI------LGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQ 198
            PG  +G P      + G  G+        +  +  G       QQQ Q+QL   P M   
Sbjct: 2104 PGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQ--PPMGGM 2161

Query: 199  IMENPLVQDMMSN----PDLMRHMIMANPQMQQLMERN--PEISHMLNNPELMRQTMELA 252
               +P  Q M  N    P   R ++     MQQ  ++   P I   + N    +Q   + 
Sbjct: 2162 ---SPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG 2218

Query: 253  RNPAMMQEMMRN----QDRALSNLESIPGGYNA--------------LRRMYTDIQEPMF 294
              P   Q M  +    Q   +  +  +P    A               ++M + +Q    
Sbjct: 2219 YPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPM 2278

Query: 295  SAAREQFGNNPFSS-LAGNS-DSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGG 352
            S  +    N   S  L G    +S S  +R+    P P P S  P +S +P    + +  
Sbjct: 2279 SPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPS-- 2336

Query: 353  SGTSQVHPTVSNPF-GINAAS---LGSGMFNSPEMQALLQQISENP 394
                 V P  S+P  G+ AA    +  G F SP+  ++L Q++ NP
Sbjct: 2337 --PHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNP 2380



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 79/326 (24%), Positives = 120/326 (36%), Gaps = 80/326 (24%)

Query: 330  PNPWSPSPPTSQAPGSGGEGT---------GGSGTSQVHPTVSNPFGINAASLGSGMFNS 380
            P P +  P     PG G  G          G     Q+   +  P  ++ A  G  +  +
Sbjct: 1969 PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMA 2028

Query: 381  PEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQL 440
            P  Q  L Q+  +P L    +S   ++++++TL ++P    Q    + +   NPQL    
Sbjct: 2029 P--QPGLGQVGISP-LKPGTVSQQALQNLLRTL-RSPSSPLQQQQVLSILHANPQL---- 2080

Query: 441  RLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPA 500
               L  F++Q     + S   NP+ +     + QG   LQ   P  +P  G  G+   PA
Sbjct: 2081 ---LAAFIKQRAAKYANS---NPQPIPGQPGMPQGQPGLQ---PPTMP--GQQGVHSNPA 2129

Query: 501  PS------AGSNAGSTPEAPTSSPATPATSSPTGASSAQ--------------------- 533
                    AG      P+        P    P G  S Q                     
Sbjct: 2130 MQNMNPMQAGVQRAGLPQQQPQQQLQP----PMGGMSPQAQQMNMNHNTMPSQFRDILRR 2185

Query: 534  QQLMQQMIQLLAGSG-------NSQVQTP---------EVRFQQQLEQL--NSMGFINRE 575
            QQ+MQQ  Q  AG G       ++Q Q P         + R Q  ++Q+   +MG I + 
Sbjct: 2186 QQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQL 2245

Query: 576  ANLQALIA-TGGDINAAIERLLGSQL 600
               QAL A  G  + A  +RLL  Q+
Sbjct: 2246 P--QALGAEAGASLQAYQQRLLQQQM 2269


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 99/480 (20%), Positives = 169/480 (35%), Gaps = 79/480 (16%)

Query: 55   IFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSP-----STPDPASAPS 109
            +  G  ++ G T+ +  ++       +I+TP   Q  A     +            SAP+
Sbjct: 2051 VITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPN 2110

Query: 110  TTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLG 169
            T  +   TP Q S + SA+S +   S  S    P  G  + + +    +  G GG  GL 
Sbjct: 2111 TVSS---TPGQKSLT-SATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLT 2166

Query: 170  SLGLGSANFMELQQQMQRQLMSNP----EMLSQIMENPLVQDMMSNPDLM---------- 215
             +  G        Q + + +   P    +++   M N  VQ  +  P             
Sbjct: 2167 VVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTT 2226

Query: 216  -----------RHMIMANPQMQQLMERN--PEISHMLNNPELMRQTMELARNPAMMQEMM 262
                       +     +PQMQ   ++   P  S  +   E   QT + +  P    +  
Sbjct: 2227 TVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQ 2286

Query: 263  RNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFG--NNPFSSLAGNSDSSSSQP 320
                  +     +         + ++ Q     +++ Q    + P S++ G S      P
Sbjct: 2287 SPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSP 2346

Query: 321  LRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINA------ASLG 374
             +T  R        PS P+  +PG           SQV  T S P  I         S G
Sbjct: 2347 SQTRIR--------PSTPSQLSPGQ---------QSQVQTTTSQPIPIQPHTSLQIPSQG 2389

Query: 375  SGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAA------------- 421
                + P++Q+  Q +S    L Q  +S+P  R  +Q     P   A             
Sbjct: 2390 QPQ-SQPQVQSSTQTLSSGQTLNQVTVSSP-SRPQLQIQQPQPQVIAVPQLQQQVQVLSQ 2447

Query: 422  -QMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ 480
             Q  V   + A    + +Q++LQLP+ +QQ    ++  I  N   +QA   +Q+ LQ +Q
Sbjct: 2448 IQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQI-QNVVTVQA-ASVQEQLQRVQ 2505



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 10/79 (12%)

Query: 277 GGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPS 336
           G    LR  +       ++AA+ +    P + L+     SSS+      R+P P P  P+
Sbjct: 34  GPIGGLRSRHRGSSRGRWAAAQAEVA--PKTRLSSPRGGSSSR------RKPPPPP--PA 83

Query: 337 PPTSQAPGSGGEGTGGSGT 355
           PP++ APG GG G GG  T
Sbjct: 84  PPSTSAPGRGGRGGGGGRT 102



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 17/43 (39%), Positives = 20/43 (46%), Gaps = 1/43 (2%)

Query: 100 STPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGG 142
           S+P   S+    P  P  PA PSTS       G G  R+ GGG
Sbjct: 65  SSPRGGSSSRRKPPPPP-PAPPSTSAPGRGGRGGGGGRTGGGG 106


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 11/139 (7%)

Query: 80  LVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASP------ATPAQPSTSGSASSDAGS 133
           L  +T   +   AA TA+  STP  + A +++ + P         A  +++G+ +S++  
Sbjct: 322 LYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPMYVSGSQVVASSTSTGAGASNSSG 381

Query: 134 GSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNP 193
           G     GGG   G G G   +T    SG G  +  G   LGSA+     Q       ++P
Sbjct: 382 GGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSAS-----QSYSHTTRASP 436

Query: 194 EMLSQIMENPLVQDMMSNP 212
             +  +++N    + +S P
Sbjct: 437 ATVQWLLDNYETAEGVSLP 455


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 92  AAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGS 151
           A + A  P+    A+ P   PA PA PA P+   + ++ AG G     G GP PG G+ +
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA---ALAARAGPGPGPGPGPGPGPGPGKPA 190

Query: 152 PSATASILSGFGGIL 166
               A  L+G   +L
Sbjct: 191 GPGAAQTLNGSAALL 205



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 14/90 (15%)

Query: 81  VIKTPQ---KAQDPAAATASSPSTP---DPASAPSTTPASPAT-------PAQPSTSGSA 127
           VI+TP     A  PA A  S P+ P    PA+AP   P +PAT       PA P T+  A
Sbjct: 237 VIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296

Query: 128 -SSDAGSGSRRSSGGGPSPGAGEGSPSATA 156
               A + +  S+G  P+P    G P+  +
Sbjct: 297 VPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 62/269 (23%), Positives = 100/269 (37%), Gaps = 40/269 (14%)

Query: 310 AGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPT-VSNPFGI 368
           +G + +++S  +    +  LP+P +  PP    P    +G  G+ T  +  T  +   GI
Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGI 423

Query: 369 NAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYM---RSMMQTLAQNPDFA-AQMM 424
            A            +   L Q  +NP  +QN    P M   RS    L   P  A AQM 
Sbjct: 424 RAT------LTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQ 477

Query: 425 VNVPLFAGNPQLQEQLRLQL-----PVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTL 479
                    PQ     R        PV +  +Q P +  I         + Q+ Q   T+
Sbjct: 478 AQA---HAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTV 534

Query: 480 QTEA-----PGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQ 534
           Q  A     PG+ P L   G ++T      ++ G+     T +P      + T +S+A +
Sbjct: 535 QPSATLQRSPGVQPQLVLGGAAQT------ASLGTATAVQTGTPQRTVPGATTTSSAATE 588

Query: 535 QL---------MQQMIQLLAGSGNSQVQT 554
            +         +  +I+ LA SG    +T
Sbjct: 589 TMENVKKCKNFLSTLIK-LASSGKQSTET 616



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 11/83 (13%)

Query: 84  TPQKAQDPAAATASSPSTPDPASAPSTTP---------ASPATPAQPSTSGSASSDAGSG 134
           +P  A  PAA  A++P  P PA A    P         A+PA P  P+ + +  S   + 
Sbjct: 256 SPPAAPAPAAP-AAAPPPPPPAPATLARPPGHPAGPPTAAPAVP-PPAAAQNGGSAGAAP 313

Query: 135 SRRSSGGGPSPGAGEGSPSATAS 157
           +   + GGP+  +G+  P A A+
Sbjct: 314 APAPAAGGPAGVSGQPGPGAAAA 336



 Score = 33.1 bits (74), Expect = 0.75
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 91  PAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEG 150
           PA    ++P+ P PA+A +   A  A PA    +G  +  +G     ++   P+PG    
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAG-AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE 345

Query: 151 SP 152
           SP
Sbjct: 346 SP 347



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 2/75 (2%)

Query: 91  PAAATASSPSTPDPASA-PSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPG-AG 148
           P       P  P P        PA PA   +P   GSA S A   +  +   GP P  AG
Sbjct: 97  PGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156

Query: 149 EGSPSATASILSGFG 163
              P+  A++ +  G
Sbjct: 157 PAKPAGPAALAARAG 171



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 6/74 (8%)

Query: 481 TEAPGLVPSL-----GSFGISRTPAPSAGSNAG-STPEAPTSSPATPATSSPTGASSAQQ 534
           T AP + P       GS G +  PAP+AG  AG S    P ++ A PA      +     
Sbjct: 292 TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV 351

Query: 535 QLMQQMIQLLAGSG 548
           Q      Q LA SG
Sbjct: 352 QAAPPAAQTLAASG 365



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 26/96 (27%), Positives = 35/96 (36%), Gaps = 21/96 (21%)

Query: 79  HLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRS 138
           HL  +TP+     A A  +   +  PA A    PA+PA  A     G+A     +G  R 
Sbjct: 42  HLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAP----GAAPEPPPAGRARP 97

Query: 139 SGGGP-----------------SPGAGEGSPSATAS 157
            GGGP                 +P A +  P    S
Sbjct: 98  GGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 55/201 (27%), Positives = 72/201 (35%), Gaps = 25/201 (12%)

Query: 352 GSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQ----------------ISENPQ 395
           GS   Q  P VS P  I+ + +      S E+    +Q                I  +P 
Sbjct: 523 GSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPV 582

Query: 396 LMQNVISAPYMRSMMQTLAQN--PDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQN 453
            +  V SA   +  + +LAQ   P   A   V  PL    P  Q Q   Q P+   QM  
Sbjct: 583 NVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAP 642

Query: 454 PESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEA 513
               S+  NP +     +  Q    LQT      PS    G   T  P A       P  
Sbjct: 643 GHVKSVTQNPAS-----EYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQ 697

Query: 514 PTSSPATPATSS--PTGASSA 532
           PT+ PA PA +S  P G + A
Sbjct: 698 PTAVPAQPAGASVQPVGQAPA 718



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 87/417 (20%), Positives = 144/417 (34%), Gaps = 44/417 (10%)

Query: 151 SPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDM-- 208
           S S++ S LS +   +G G +G  +   ++ QQQ Q+Q    P +    ++         
Sbjct: 469 SVSSSVSTLSHYTESVGSGEMGAPTV-VVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGP 527

Query: 209 MSNPDLMRHMIMANPQMQQLMERNPEISHMLNN---PELMRQTMELARNPAMMQEMMRNQ 265
            S P +     ++  Q+ Q+  ++ E+S+       P  ++ TM  A         +   
Sbjct: 528 QSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGV 587

Query: 266 DRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGNSDSSSSQPLRTEN 325
             AL    SI              Q P   AA       P +           QP+ +  
Sbjct: 588 TSALGQQPSISS--------LAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQ 639

Query: 326 REP------LPNPWSP----SPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGS 375
             P        NP S      P    A  SG   + G G       V+ P GI      +
Sbjct: 640 MAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPT 699

Query: 376 GMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVP---LFAG 432
            +   P   A +Q + + P  +  V +   + ++ Q  A  P    Q    VP   +  G
Sbjct: 700 AVPAQPA-GASVQPVGQAPAAVSAVPTGSQIANIGQQ-ANIPTAVQQPSTQVPPSVIQQG 757

Query: 433 NPQ------------LQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ 480
            P             + + ++   P   QQ+      S+LT P   Q +  + QG+ + Q
Sbjct: 758 APPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQ 817

Query: 481 TEAPGLVPSLGSFGISRTPAPSAGSNAGSTPE---APTSSPATPATSSPTGASSAQQ 534
             A   +PS  S  ++   + +  S   S P     P +   TPAT +     S  Q
Sbjct: 818 LPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQ 874


>gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 91  PAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEG 150
           P ++++SS  +   A  PS+T +S  T A P+ S  A++ A S S       P+P +G G
Sbjct: 201 PGSSSSSSSRSQSAAVTPSSTTSS--TRATPAPSAPAAASATSPS-------PAPSSGNG 251

Query: 151 SPSATASI----LSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQ 206
           + +A +      LS    IL   ++  G A      QQ+    +  PE+++ I       
Sbjct: 252 ASTAASPTQPIQLSDLQSILATMNVPAGPAG----GQQVDLASVLTPEIMAPI------- 300

Query: 207 DMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMR 246
             ++N D+   ++   P  + L +   EI + L +P+  +
Sbjct: 301 --LANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQ 338



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 13/111 (11%)

Query: 484 PGLVPSLGSFGI--SRTPAPSAGSNAGSTPEAPTSSP-ATPATSSPTGASSAQQQLMQQM 540
           PGL   LGS G   S + + S   +A  TP + TSS  ATPA S+P  AS+         
Sbjct: 189 PGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPS- 247

Query: 541 IQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAA 591
               +G+G S   +P      Q  QL+ +  I    N+ A  A G  ++ A
Sbjct: 248 ----SGNGASTAASP-----TQPIQLSDLQSILATMNVPAGPAGGQQVDLA 289



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 9/87 (10%)

Query: 480 QTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQ 539
           ++++  + PS  +     TPAPSA + A +T  +P  S    A+++ +     Q   +Q 
Sbjct: 210 RSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQS 269

Query: 540 MIQLL---AGSGNSQ------VQTPEV 557
           ++  +   AG    Q      V TPE+
Sbjct: 270 ILATMNVPAGPAGGQQVDLASVLTPEI 296


>gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 91  PAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEG 150
           P ++++SS  +   A  PS+T +S  T A P+ S  A++ A S S       P+P +G G
Sbjct: 201 PGSSSSSSSRSQSAAVTPSSTTSS--TRATPAPSAPAAASATSPS-------PAPSSGNG 251

Query: 151 SPSATASI----LSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQ 206
           + +A +      LS    IL   ++  G A      QQ+    +  PE+++ I       
Sbjct: 252 ASTAASPTQPIQLSDLQSILATMNVPAGPAG----GQQVDLASVLTPEIMAPI------- 300

Query: 207 DMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMR 246
             ++N D+   ++   P  + L +   EI + L +P+  +
Sbjct: 301 --LANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQ 338



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 13/111 (11%)

Query: 484 PGLVPSLGSFGI--SRTPAPSAGSNAGSTPEAPTSSP-ATPATSSPTGASSAQQQLMQQM 540
           PGL   LGS G   S + + S   +A  TP + TSS  ATPA S+P  AS+         
Sbjct: 189 PGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPS- 247

Query: 541 IQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAA 591
               +G+G S   +P      Q  QL+ +  I    N+ A  A G  ++ A
Sbjct: 248 ----SGNGASTAASP-----TQPIQLSDLQSILATMNVPAGPAGGQQVDLA 289



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 9/87 (10%)

Query: 480 QTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQ 539
           ++++  + PS  +     TPAPSA + A +T  +P  S    A+++ +     Q   +Q 
Sbjct: 210 RSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQS 269

Query: 540 MIQLL---AGSGNSQ------VQTPEV 557
           ++  +   AG    Q      V TPE+
Sbjct: 270 ILATMNVPAGPAGGQQVDLASVLTPEI 296


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 108/524 (20%), Positives = 173/524 (33%), Gaps = 114/524 (21%)

Query: 108  PSTTPASPATPAQPSTSGSASSDAGSGSRRSSGGGPSPG---AGEGSPSATASILSGFGG 164
            PSTT  +P     P    + +     G     G GP         G P+     L G  G
Sbjct: 534  PSTTATTPGNSGAPQLQANQNVQHAGGQ----GAGPPQNQMQVSHGPPNMMQPSLMGIHG 589

Query: 165  ILG---LGSLGLGSANFMELQQQMQR----QLMS----------------------NPEM 195
             +     G+ G+   N   +Q Q Q+    QLM                       NP +
Sbjct: 590  NMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMI 649

Query: 196  LS--------QIMENPLVQDMMSNPDLMR----------------HMIMANPQMQQLMER 231
            LS        Q+M NP  Q++  +P  M                 H  M  PQ Q L+++
Sbjct: 650  LSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQ 709

Query: 232  NPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLES--IPGGYNALRRMYTDI 289
            NP I  ++ N                  +M  N+ +  +  +S  +PG    +R    ++
Sbjct: 710  NPMIEQIMTN------------------QMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 751

Query: 290  QEPMFSAAREQFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEG 349
            Q  M     +  G        G  ++S SQ +  + +  +  P  PSP  +Q  G     
Sbjct: 752  QGNMVQFTGQMSGQ--MLPQQGPVNNSPSQVMGIQGQ--VLRPPGPSPHMAQQHGDPATT 807

Query: 350  TGGS-GTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVIS--APYM 406
                   SQ+ P V         S+       P +QA+    +       + +S  AP+ 
Sbjct: 808  ANNDVSLSQMMPDV---------SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFS 858

Query: 407  ---RSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNP 463
                    +  QNP F     VN  +   +P L   L+  +      + N ++ +    P
Sbjct: 859  GAPNGNQMSCGQNPGFP----VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKP 914

Query: 464  RAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAG-----STPEAPTSSP 518
            +  +   + +   Q L T      P     G+     P      G     S P+ P  S 
Sbjct: 915  KKKKPPRKKKNSQQDLNT------PDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSN 968

Query: 519  ATPATSSPTGASSAQQQLMQQMIQLLAGSGNSQVQTPEVRFQQQ 562
              P   S        QQ+  Q++Q +A       Q P+ +  QQ
Sbjct: 969  RPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQ 1012



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 62/247 (25%), Positives = 86/247 (34%), Gaps = 38/247 (15%)

Query: 303  NNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTV 362
            N P          +S Q L T +  P     +  PP    PG  G     SG     P  
Sbjct: 912  NKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL---PGEQGINLDNSGPKL--PEF 966

Query: 363  SNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQ 422
            SN           G  + P  Q  LQQ+   PQLMQ+V   P      Q   Q P    Q
Sbjct: 967  SNR--------PPGYPSQPVEQRPLQQMP--PQLMQHVAPPP-QPPQQQPQPQLP----Q 1011

Query: 423  MMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTE 482
                 P      Q Q+Q + Q+ + L   Q+P+S+ +  +         +    Q +  +
Sbjct: 1012 QQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQ 1071

Query: 483  APGLVPSLGSF----------GISRTPAP---SAGSNA-----GSTPEAPTSSPATPATS 524
              G VP + S              R P P     GSN+       +P+ P+SSP     S
Sbjct: 1072 QSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMAS 1131

Query: 525  SPTGASS 531
             P  + S
Sbjct: 1132 LPEASGS 1138



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 52/267 (19%), Positives = 98/267 (36%), Gaps = 57/267 (21%)

Query: 210  SNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRAL 269
            S P     ++ ++P +QQ+ E NP+ +    N    + T+  +++  M+  ++ N   + 
Sbjct: 1745 SPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSS 1804

Query: 270  SNLESIPGGYNALRRMYTDIQEPMFSAA-----------REQFGNNPFSSLAGNSDSS-- 316
             N  S P   +  +     I + + + A            EQ+G +  +   G   ++  
Sbjct: 1805 GNRRS-PVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPG 1863

Query: 317  --SSQPLRTENREPLPNPWSP------SPPTSQAPGSGGEGTGGSG-------------- 354
               ++ L TE     P P +P      S P      S G    G                
Sbjct: 1864 LMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVP 1923

Query: 355  ---TSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLM------QNVISAPY 405
                S V  T SN  GI + SL  G+          +++  +P+L+      QN++S   
Sbjct: 1924 SELISAVPTTKSNHGGIASESLAGGLVE--------EKVGSHPELLPSIAPSQNLVSKET 1975

Query: 406  MRSMMQTLAQNPDFAAQMMVNVPLFAG 432
              + +Q     P    ++ VN  + +G
Sbjct: 1976 STTALQASVARP----ELEVNAAIVSG 1998


>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 12/85 (14%)

Query: 82  IKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQP------STSGSASSDAGSGS 135
           I TP     PA   A +P TP P + P T P  PA P  P      + S +A S  G+G+
Sbjct: 727 IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGT 786

Query: 136 -----RRSSGGGPSPGAGEGSPSAT 155
                 ++ G  P P A +G P  T
Sbjct: 787 AAPAPSQTPGSAPPPQA-QGPPYPT 810



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)

Query: 89  QDPAAATASSPSTPDPA--SAP----STTPASPA----TPAQPSTSGSASSDAGSGSRRS 138
           Q   A   S+PS P PA  S+P    + TP +PA     P +P             +R  
Sbjct: 715 QQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP 774

Query: 139 SGGGPSP-GAGEGSPS 153
           S   PSP GAG  +P+
Sbjct: 775 SATAPSPVGAGTAAPA 790


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 12/85 (14%)

Query: 82  IKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQP------STSGSASSDAGSGS 135
           I TP     PA   A +P TP P + P T P  PA P  P      + S +A S  G+G+
Sbjct: 722 IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGT 781

Query: 136 -----RRSSGGGPSPGAGEGSPSAT 155
                 ++ G  P P A +G P  T
Sbjct: 782 AAPAPSQTPGSAPPPQA-QGPPYPT 805



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)

Query: 89  QDPAAATASSPSTPDPA--SAP----STTPASPA----TPAQPSTSGSASSDAGSGSRRS 138
           Q   A   S+PS P PA  S+P    + TP +PA     P +P             +R  
Sbjct: 710 QQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP 769

Query: 139 SGGGPSP-GAGEGSPS 153
           S   PSP GAG  +P+
Sbjct: 770 SATAPSPVGAGTAAPA 785


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 26/68 (38%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 78  VHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPATPAQPSTSGSASSDAGSGSRR 137
           +H V   P  AQ P       P TP    + ST PA P T AQP  SG+A+S    GS  
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAAS---GGSIA 527

Query: 138 SSGGGPSP 145
                P P
Sbjct: 528 GGSSCPLP 535



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 23/63 (36%), Positives = 26/63 (41%), Gaps = 7/63 (11%)

Query: 477 QTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQL 536
           Q LQ + P L    G      TPAPS  S    TP+ PT  P   AT+ P   S    Q 
Sbjct: 178 QMLQAQPPALQAPTGV-----TPAPS--SAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 230

Query: 537 MQQ 539
             Q
Sbjct: 231 PNQ 233



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 38/141 (26%), Positives = 57/141 (40%), Gaps = 20/141 (14%)

Query: 18  KTPKDKEEIVICDRASVKEFK-EEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGL 76
           K   D EE    DR S K+ K +EISR     + +     +  +  +G +  +   +D  
Sbjct: 99  KVASDTEE---ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR 155

Query: 77  TVHLVIKTPQKAQD--------------PAAATASSPSTPDPASAPSTTPASPATPAQPS 122
           +    I +PQ  +               P A  A +  TP P+SAP  TP  P TP  P+
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP-TPG-PT 213

Query: 123 TSGSASSDAGSGSRRSSGGGP 143
            S +A    GS +   +   P
Sbjct: 214 PSATAVPPQGSPTASQAPNQP 234



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 63/267 (23%), Positives = 89/267 (33%), Gaps = 45/267 (16%)

Query: 335 PSPPTSQAPGSGGEGTGGSGTSQV-----HPTVSNPFGI------NAASLGSG------- 376
           PS P+   P   G+G  G  + Q      HP    PFG+        A LG+        
Sbjct: 282 PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH 341

Query: 377 -MFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPD---FAAQMMVNVPLFAG 432
                P  Q+ LQ  S+ P   Q +  AP     ++     P     A Q   + P  +G
Sbjct: 342 TSLQLPASQSALQ--SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 399

Query: 433 NPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQI---QQGLQTLQTEAPGLV-- 487
                    L  P  L+ +    SLS    P A    LQ+    Q L +   + PGL   
Sbjct: 400 PSPFSMNANLPPPPALKPL---SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQS 456

Query: 488 ----------PSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLM 537
                     P  G   ++  P P A          P + P  P+TS+P        Q  
Sbjct: 457 QNLPPPPASHPPTGLHQVAPQP-PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 515

Query: 538 QQMIQLLAGS--GNSQVQTPEVRFQQQ 562
                   GS  G S    P V+ +++
Sbjct: 516 CSGAAASGGSIAGGSSCPLPTVQIKEE 542


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,605,966
Number of Sequences: 37866
Number of extensions: 1473884
Number of successful extensions: 29078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 454
Number of HSP's successfully gapped in prelim test: 1003
Number of HSP's that attempted gapping in prelim test: 17090
Number of HSP's gapped (non-prelim): 11080
length of query: 601
length of database: 18,247,518
effective HSP length: 108
effective length of query: 493
effective length of database: 14,157,990
effective search space: 6979889070
effective search space used: 6979889070
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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