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Search of human proteins with 40538772
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40538772 protein arginine methyltransferase 10 (putative)
[Homo sapiens]
(845 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40538772 protein arginine methyltransferase 10 (putative) [Ho... 1688 0.0
gi|9506615 protein arginine methyltransferase 7 [Homo sapiens] 87 8e-17
gi|150456457 HMT1 hnRNP methyltransferase-like 2 isoform 2 [Homo... 75 2e-13
gi|154759421 HMT1 hnRNP methyltransferase-like 2 isoform 1 [Homo... 75 3e-13
gi|151301219 HMT1 hnRNP methyltransferase-like 2 isoform 3 [Homo... 75 3e-13
gi|227908867 protein arginine methyltransferase 6 [Homo sapiens] 73 1e-12
gi|223556010 protein arginine methyltransferase 3 isoform 3 [Hom... 72 2e-12
gi|223556008 protein arginine methyltransferase 3 isoform 2 [Hom... 72 2e-12
gi|44771198 protein arginine methyltransferase 3 isoform 1 [Homo... 72 2e-12
gi|40288288 coactivator-associated arginine methyltransferase 1 ... 69 2e-11
gi|74099699 HMT1 hnRNP methyltransferase-like 4 [Homo sapiens] 68 4e-11
gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens] 60 6e-09
gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens] 60 6e-09
gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens] 39 0.015
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 38 0.034
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 38 0.034
gi|83415184 transmembrane and tetratricopeptide repeat containin... 35 0.38
gi|20270349 MIT, microtubule interacting and transport, domain c... 33 0.85
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 33 1.4
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap... 33 1.4
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap... 33 1.4
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap... 33 1.4
gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi... 33 1.4
gi|239756067 PREDICTED: similar to Putative ankyrin repeat domai... 32 2.5
gi|239744894 PREDICTED: similar to Putative ankyrin repeat domai... 32 2.5
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 32 3.2
gi|34222104 hypothetical protein LOC26074 [Homo sapiens] 31 5.5
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom... 30 7.2
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad... 30 7.2
gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens] 30 9.4
>gi|40538772 protein arginine methyltransferase 10 (putative) [Homo
sapiens]
Length = 845
Score = 1688 bits (4372), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MSNSRPRSRRDAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKH 60
MSNSRPRSRRDAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKH
Sbjct: 1 MSNSRPRSRRDAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKH 60
Query: 61 DVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEA 120
DVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEA
Sbjct: 61 DVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEA 120
Query: 121 AGYFHKAVKLNPDFSDAKENFYRVANWLVERWHFIMLNDTKRNTIYNAAIQKAVCLGSKS 180
AGYFHKAVKLNPDFSDAKENFYRVANWLVERWHFIMLNDTKRNTIYNAAIQKAVCLGSKS
Sbjct: 121 AGYFHKAVKLNPDFSDAKENFYRVANWLVERWHFIMLNDTKRNTIYNAAIQKAVCLGSKS 180
Query: 181 VLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLHTKSLDIE 240
VLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLHTKSLDIE
Sbjct: 181 VLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLHTKSLDIE 240
Query: 241 IPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKTKGESANCEKYGKVIPAS 300
IPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKTKGESANCEKYGKVIPAS
Sbjct: 241 IPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKTKGESANCEKYGKVIPAS 300
Query: 301 AVIFGMAVECAEIRRHHRVGIKDIAGIHLPTNVKFQSPAYSSVDTEETIEPYTTEKMSRV 360
AVIFGMAVECAEIRRHHRVGIKDIAGIHLPTNVKFQSPAYSSVDTEETIEPYTTEKMSRV
Sbjct: 301 AVIFGMAVECAEIRRHHRVGIKDIAGIHLPTNVKFQSPAYSSVDTEETIEPYTTEKMSRV 360
Query: 361 PGGYLALTECFEIMTVDFNNLQELKSLATKKPDKIGIPVIKEGILDAIMVWFVLQLDDEH 420
PGGYLALTECFEIMTVDFNNLQELKSLATKKPDKIGIPVIKEGILDAIMVWFVLQLDDEH
Sbjct: 361 PGGYLALTECFEIMTVDFNNLQELKSLATKKPDKIGIPVIKEGILDAIMVWFVLQLDDEH 420
Query: 421 SLSTSPSEETCWEQAVYPVQDLADYWIKPGDHVMMEVSCQDCYLRIQSISVLGLECEMDV 480
SLSTSPSEETCWEQAVYPVQDLADYWIKPGDHVMMEVSCQDCYLRIQSISVLGLECEMDV
Sbjct: 421 SLSTSPSEETCWEQAVYPVQDLADYWIKPGDHVMMEVSCQDCYLRIQSISVLGLECEMDV 480
Query: 481 AKSFTQNKDLLSLGNEAELCSALANLQTSKPDAVEQTCILESTEIALLNNIPYHEGFKMA 540
AKSFTQNKDLLSLGNEAELCSALANLQTSKPDAVEQTCILESTEIALLNNIPYHEGFKMA
Sbjct: 481 AKSFTQNKDLLSLGNEAELCSALANLQTSKPDAVEQTCILESTEIALLNNIPYHEGFKMA 540
Query: 541 MSKVLSSLTPEKLYQTMDTHCQNEMSSGTGQSNTVQNILEPFYVLDVSEGFSVLPVIAGT 600
MSKVLSSLTPEKLYQTMDTHCQNEMSSGTGQSNTVQNILEPFYVLDVSEGFSVLPVIAGT
Sbjct: 541 MSKVLSSLTPEKLYQTMDTHCQNEMSSGTGQSNTVQNILEPFYVLDVSEGFSVLPVIAGT 600
Query: 601 LGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFWLRHVEDESAMLQRPKSDKLWSIII 660
LGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFWLRHVEDESAMLQRPKSDKLWSIII
Sbjct: 601 LGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFWLRHVEDESAMLQRPKSDKLWSIII 660
Query: 661 LDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGLLVESQTLLEENAVQGTERT 720
LDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGLLVESQTLLEENAVQGTERT
Sbjct: 661 LDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGLLVESQTLLEENAVQGTERT 720
Query: 721 LGLNIAPFINQFQVPIRVFLDLSSLPCIPLSKPVELLRLDLMTPYLNTSNREVKVYVCKS 780
LGLNIAPFINQFQVPIRVFLDLSSLPCIPLSKPVELLRLDLMTPYLNTSNREVKVYVCKS
Sbjct: 721 LGLNIAPFINQFQVPIRVFLDLSSLPCIPLSKPVELLRLDLMTPYLNTSNREVKVYVCKS 780
Query: 781 GRLTAIPFWYHMYLDEEIRLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKSNVS 840
GRLTAIPFWYHMYLDEEIRLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKSNVS
Sbjct: 781 GRLTAIPFWYHMYLDEEIRLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKSNVS 840
Query: 841 ITVKQ 845
ITVKQ
Sbjct: 841 ITVKQ 845
>gi|9506615 protein arginine methyltransferase 7 [Homo sapiens]
Length = 692
Score = 86.7 bits (213), Expect = 8e-17
Identities = 79/303 (26%), Positives = 138/303 (45%), Gaps = 34/303 (11%)
Query: 156 MLNDTKRNTIYNAAIQKAVCL----GSKS-VLDIGAGTGILSMFAKKAGAHSVYACELSK 210
ML+D RN Y I+ AV G K+ VLDIG GTG+LSM A AGA YA E+ K
Sbjct: 38 MLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFK 97
Query: 211 TMYELACDVVAANKMEAGIKLLHTKSLDIEIPKH--IPERVSLVVTETVDAGLFGEGIVE 268
M + A +V N IK+++ S ++ + +P R +++VTE D L GEG +
Sbjct: 98 PMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALP 157
Query: 269 SLIHAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIH 328
S HA HL+ NCE +P A ++ VE + ++ + IH
Sbjct: 158 SYEHAHRHLV--------EENCE----AVPHRATVYAQLVESGRMWSWNK-----LFPIH 200
Query: 329 LPTNVKFQSPAYSSVDTEET--IEPYTTEKMSRV-PGGYLALTECFEIMTVDFNNLQELK 385
+ T++ + VD E ++++V P + L++ + ++DF+ +++
Sbjct: 201 VQTSLG-EQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFS--KQVS 257
Query: 386 SLATKKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSPSEETCWEQAVYPVQDLADY 445
S A + + G ++ W+ +++D E + + + W + D+
Sbjct: 258 SSAACHSRR--FEPLTSGRAQVVLSWWDIEMDPEGKIKCTMA--PFWAHSDPEEMQWRDH 313
Query: 446 WIK 448
W++
Sbjct: 314 WMQ 316
>gi|150456457 HMT1 hnRNP methyltransferase-like 2 isoform 2 [Homo
sapiens]
Length = 347
Score = 75.5 bits (184), Expect = 2e-13
Identities = 81/348 (23%), Positives = 156/348 (44%), Gaps = 50/348 (14%)
Query: 114 MGFRDEAAGYFHKAVKLNPDFSDAKENFY-RVANWLVERWHFIMLNDTKRNTIY-NAAIQ 171
+G + + G + K N + +K+ ++ A++ + H ML D R Y N+
Sbjct: 2 VGVAEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGI---HEEMLKDEVRTLTYRNSMFH 58
Query: 172 KAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKL 231
K VLD+G+GTGIL MFA KAGA V E S ++ + A +V ANK++ + +
Sbjct: 59 NRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS-SISDYAVKIVKANKLDHVVTI 117
Query: 232 LHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKTKGESANCE 291
+ K ++E+P E+V ++++E + LF E ++ ++++A + L
Sbjct: 118 IKGKVEEVELP---VEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPD---------- 164
Query: 292 KYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP--TNVKFQSPAYSSVDTEETI 349
G + P A ++ A+E + + + +++ G + +V + P VD ++ +
Sbjct: 165 --GLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLV 222
Query: 350 EPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLATKKPDKIGIPVIKEGILDAIM 409
T I VD + +++ L P + V + + A++
Sbjct: 223 ------------------TNACLIKEVDIYTV-KVEDLTFTSP--FCLQVKRNDYVHALV 261
Query: 410 VWFVLQLDDEH---SLSTSP-SEETCWEQAVYPVQDLADYWIKPGDHV 453
+F ++ H STSP S T W+Q V+ ++D +K G+ +
Sbjct: 262 AYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLT--VKTGEEI 307
>gi|154759421 HMT1 hnRNP methyltransferase-like 2 isoform 1 [Homo
sapiens]
Length = 371
Score = 75.1 bits (183), Expect = 3e-13
Identities = 75/308 (24%), Positives = 138/308 (44%), Gaps = 46/308 (14%)
Query: 153 HFIMLNDTKRNTIY-NAAIQKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H ML D R Y N+ K VLD+G+GTGIL MFA KAGA V E S +
Sbjct: 63 HEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS-S 121
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+ + A +V ANK++ + ++ K ++E+P E+V ++++E + LF E ++ +++
Sbjct: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEVELP---VEKVDIIISEWMGYCLFYESMLNTVL 178
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP- 330
+A + L G + P A ++ A+E + + + +++ G +
Sbjct: 179 YARDKWLAPD------------GLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSC 226
Query: 331 -TNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389
+V + P VD ++ + T I VD + +++ L
Sbjct: 227 IKDVAIKEPLVDVVDPKQLV------------------TNACLIKEVDIYTV-KVEDLTF 267
Query: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEH---SLSTSP-SEETCWEQAVYPVQDLADY 445
P + V + + A++ +F ++ H STSP S T W+Q V+ ++D
Sbjct: 268 TSP--FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLT- 324
Query: 446 WIKPGDHV 453
+K G+ +
Sbjct: 325 -VKTGEEI 331
>gi|151301219 HMT1 hnRNP methyltransferase-like 2 isoform 3 [Homo
sapiens]
Length = 353
Score = 75.1 bits (183), Expect = 3e-13
Identities = 75/308 (24%), Positives = 138/308 (44%), Gaps = 46/308 (14%)
Query: 153 HFIMLNDTKRNTIY-NAAIQKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H ML D R Y N+ K VLD+G+GTGIL MFA KAGA V E S +
Sbjct: 45 HEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS-S 103
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+ + A +V ANK++ + ++ K ++E+P E+V ++++E + LF E ++ +++
Sbjct: 104 ISDYAVKIVKANKLDHVVTIIKGKVEEVELP---VEKVDIIISEWMGYCLFYESMLNTVL 160
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP- 330
+A + L G + P A ++ A+E + + + +++ G +
Sbjct: 161 YARDKWLAPD------------GLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSC 208
Query: 331 -TNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389
+V + P VD ++ + T I VD + +++ L
Sbjct: 209 IKDVAIKEPLVDVVDPKQLV------------------TNACLIKEVDIYTV-KVEDLTF 249
Query: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEH---SLSTSP-SEETCWEQAVYPVQDLADY 445
P + V + + A++ +F ++ H STSP S T W+Q V+ ++D
Sbjct: 250 TSP--FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLT- 306
Query: 446 WIKPGDHV 453
+K G+ +
Sbjct: 307 -VKTGEEI 313
>gi|227908867 protein arginine methyltransferase 6 [Homo sapiens]
Length = 375
Score = 72.8 bits (177), Expect = 1e-12
Identities = 54/153 (35%), Positives = 83/153 (54%), Gaps = 18/153 (11%)
Query: 153 HFIMLNDTKRNTIYNAAIQKA-VCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H M+ D R Y I + L K+VLD+GAGTGILS+F +AGA VYA E S
Sbjct: 57 HEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-A 115
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+++ A +VV N +E + +L +E +PE+V +V+E + GL E ++ S++
Sbjct: 116 IWQQAREVVRFNGLEDRVHVLPGPVETVE----LPEQVDAIVSEWMGYGLLHESMLSSVL 171
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIF 304
HA +TK ++ G ++PASA +F
Sbjct: 172 HA--------RTKW----LKEGGLLLPASAELF 192
Score = 30.4 bits (67), Expect = 7.2
Identities = 11/23 (47%), Positives = 17/23 (73%)
Query: 806 ASHWKQAAVVLDNPIQVEMGEEL 828
A+HWKQA + L+ P+QVE ++
Sbjct: 315 ATHWKQALLYLNEPVQVEQDTDV 337
>gi|223556010 protein arginine methyltransferase 3 isoform 3 [Homo
sapiens]
Length = 454
Score = 72.4 bits (176), Expect = 2e-12
Identities = 83/310 (26%), Positives = 137/310 (44%), Gaps = 39/310 (12%)
Query: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H ML D R Y I Q K VLD+G GTGILSMFA KAGA V + S+
Sbjct: 153 HEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEI 212
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+Y+ A D++ NK+E I L+ K ++ +P E+V ++++E + L E +++S++
Sbjct: 213 LYQ-AMDIIRLNKLEDTITLIKGKIEEVHLP---VEKVDVIISEWMGYFLLFESMLDSVL 268
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRH-HRVGI-KDIAGIHL 329
+A L K G V P I +AV +++ +H R+ D+ G +
Sbjct: 269 YAKNKYL------------AKGGSVYPDICTISLVAV--SDVNKHADRIAFWDDVYGFKM 314
Query: 330 PTNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389
K +V E +E + + P G + +C D E S T
Sbjct: 315 SCMKK-------AVIPEAVVEVLDPKTLISEPCG-IKHIDCHTTSISDL----EFSSDFT 362
Query: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSP-SEETCWEQAVYPVQDLADYWIK 448
K + + G D ++F + ST P S +T W+Q V+ ++ + +K
Sbjct: 363 LKITRTSMCTAIAGYFD---IYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLE--KPFSVK 417
Query: 449 PGDHVMMEVS 458
G+ + +V+
Sbjct: 418 AGEALKGKVT 427
Score = 37.7 bits (86), Expect = 0.045
Identities = 54/274 (19%), Positives = 111/274 (40%), Gaps = 30/274 (10%)
Query: 577 NILEPFYVLDVSEGFSVLPVIAGTLGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFW 636
+I + VLDV G +L + A G K + + A+D+I
Sbjct: 175 HIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIR------------- 221
Query: 637 LRHVEDESAMLQRPKSDKLWSIIILDVI--EPSG--LIQQEIMEKAAISRC-LLQSGGKI 691
L +ED +++ + + +DVI E G L+ + +++ ++ L GG +
Sbjct: 222 LNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSV 281
Query: 692 FPQYVLMFGLLVESQTLLEENAVQGTERTLGLNIAPFINQFQVPIRVFLDLSSLPCIPLS 751
+P + L+ S + + + G ++ + + +P V L P +S
Sbjct: 282 YPD-ICTISLVAVSDVNKHADRIAFWDDVYGFKMS-CMKKAVIPEAVVEVLD--PKTLIS 337
Query: 752 KPVELLRLDLMTPYLNTS--NREVKVYVCKSGRLTAIPFWYHMYLDEEIR------LDTS 803
+P + +D T ++ + + + + ++ TAI ++ +Y ++
Sbjct: 338 EPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQ 397
Query: 804 SEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKS 837
S +HWKQ +L+ P V+ GE L + HK+
Sbjct: 398 STKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKN 431
>gi|223556008 protein arginine methyltransferase 3 isoform 2 [Homo
sapiens]
Length = 469
Score = 72.4 bits (176), Expect = 2e-12
Identities = 83/310 (26%), Positives = 137/310 (44%), Gaps = 39/310 (12%)
Query: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H ML D R Y I Q K VLD+G GTGILSMFA KAGA V + S+
Sbjct: 168 HEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEI 227
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+Y+ A D++ NK+E I L+ K ++ +P E+V ++++E + L E +++S++
Sbjct: 228 LYQ-AMDIIRLNKLEDTITLIKGKIEEVHLP---VEKVDVIISEWMGYFLLFESMLDSVL 283
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRH-HRVGI-KDIAGIHL 329
+A L K G V P I +AV +++ +H R+ D+ G +
Sbjct: 284 YAKNKYL------------AKGGSVYPDICTISLVAV--SDVNKHADRIAFWDDVYGFKM 329
Query: 330 PTNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389
K +V E +E + + P G + +C D E S T
Sbjct: 330 SCMKK-------AVIPEAVVEVLDPKTLISEPCG-IKHIDCHTTSISDL----EFSSDFT 377
Query: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSP-SEETCWEQAVYPVQDLADYWIK 448
K + + G D ++F + ST P S +T W+Q V+ ++ + +K
Sbjct: 378 LKITRTSMCTAIAGYFD---IYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLE--KPFSVK 432
Query: 449 PGDHVMMEVS 458
G+ + +V+
Sbjct: 433 AGEALKGKVT 442
Score = 37.7 bits (86), Expect = 0.045
Identities = 54/274 (19%), Positives = 111/274 (40%), Gaps = 30/274 (10%)
Query: 577 NILEPFYVLDVSEGFSVLPVIAGTLGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFW 636
+I + VLDV G +L + A G K + + A+D+I
Sbjct: 190 HIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIR------------- 236
Query: 637 LRHVEDESAMLQRPKSDKLWSIIILDVI--EPSG--LIQQEIMEKAAISRC-LLQSGGKI 691
L +ED +++ + + +DVI E G L+ + +++ ++ L GG +
Sbjct: 237 LNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSV 296
Query: 692 FPQYVLMFGLLVESQTLLEENAVQGTERTLGLNIAPFINQFQVPIRVFLDLSSLPCIPLS 751
+P + L+ S + + + G ++ + + +P V L P +S
Sbjct: 297 YPD-ICTISLVAVSDVNKHADRIAFWDDVYGFKMS-CMKKAVIPEAVVEVLD--PKTLIS 352
Query: 752 KPVELLRLDLMTPYLNTS--NREVKVYVCKSGRLTAIPFWYHMYLDEEIR------LDTS 803
+P + +D T ++ + + + + ++ TAI ++ +Y ++
Sbjct: 353 EPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQ 412
Query: 804 SEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKS 837
S +HWKQ +L+ P V+ GE L + HK+
Sbjct: 413 STKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKN 446
>gi|44771198 protein arginine methyltransferase 3 isoform 1 [Homo
sapiens]
Length = 531
Score = 72.4 bits (176), Expect = 2e-12
Identities = 83/310 (26%), Positives = 137/310 (44%), Gaps = 39/310 (12%)
Query: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H ML D R Y I Q K VLD+G GTGILSMFA KAGA V + S+
Sbjct: 230 HEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEI 289
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+Y+ A D++ NK+E I L+ K ++ +P E+V ++++E + L E +++S++
Sbjct: 290 LYQ-AMDIIRLNKLEDTITLIKGKIEEVHLP---VEKVDVIISEWMGYFLLFESMLDSVL 345
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRH-HRVGI-KDIAGIHL 329
+A L K G V P I +AV +++ +H R+ D+ G +
Sbjct: 346 YAKNKYL------------AKGGSVYPDICTISLVAV--SDVNKHADRIAFWDDVYGFKM 391
Query: 330 PTNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389
K +V E +E + + P G + +C D E S T
Sbjct: 392 SCMKK-------AVIPEAVVEVLDPKTLISEPCG-IKHIDCHTTSISDL----EFSSDFT 439
Query: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSP-SEETCWEQAVYPVQDLADYWIK 448
K + + G D ++F + ST P S +T W+Q V+ ++ + +K
Sbjct: 440 LKITRTSMCTAIAGYFD---IYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLE--KPFSVK 494
Query: 449 PGDHVMMEVS 458
G+ + +V+
Sbjct: 495 AGEALKGKVT 504
Score = 37.7 bits (86), Expect = 0.045
Identities = 54/274 (19%), Positives = 111/274 (40%), Gaps = 30/274 (10%)
Query: 577 NILEPFYVLDVSEGFSVLPVIAGTLGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFW 636
+I + VLDV G +L + A G K + + A+D+I
Sbjct: 252 HIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIR------------- 298
Query: 637 LRHVEDESAMLQRPKSDKLWSIIILDVI--EPSG--LIQQEIMEKAAISRC-LLQSGGKI 691
L +ED +++ + + +DVI E G L+ + +++ ++ L GG +
Sbjct: 299 LNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSV 358
Query: 692 FPQYVLMFGLLVESQTLLEENAVQGTERTLGLNIAPFINQFQVPIRVFLDLSSLPCIPLS 751
+P + L+ S + + + G ++ + + +P V L P +S
Sbjct: 359 YPD-ICTISLVAVSDVNKHADRIAFWDDVYGFKMS-CMKKAVIPEAVVEVLD--PKTLIS 414
Query: 752 KPVELLRLDLMTPYLNTS--NREVKVYVCKSGRLTAIPFWYHMYLDEEIR------LDTS 803
+P + +D T ++ + + + + ++ TAI ++ +Y ++
Sbjct: 415 EPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQ 474
Query: 804 SEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKS 837
S +HWKQ +L+ P V+ GE L + HK+
Sbjct: 475 STKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKN 508
>gi|40288288 coactivator-associated arginine methyltransferase 1
[Homo sapiens]
Length = 608
Score = 68.6 bits (166), Expect = 2e-11
Identities = 45/123 (36%), Positives = 70/123 (56%), Gaps = 6/123 (4%)
Query: 156 MLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYE 214
M+ D R Y AI Q K VLD+G G+GILS FA +AGA +YA E S TM +
Sbjct: 162 MMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEAS-TMAQ 220
Query: 215 LACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLIHAW 274
A +V +N + I ++ K ++ +PE+V ++++E + LF E ++ES +HA
Sbjct: 221 HAEVLVKSNNLTDRIVVIPGKVEEVS----LPEQVDIIISEPMGYMLFNERMLESYLHAK 276
Query: 275 EHL 277
++L
Sbjct: 277 KYL 279
>gi|74099699 HMT1 hnRNP methyltransferase-like 4 [Homo sapiens]
Length = 394
Score = 67.8 bits (164), Expect = 4e-11
Identities = 75/345 (21%), Positives = 148/345 (42%), Gaps = 52/345 (15%)
Query: 153 HFIMLNDTKRNTIY-NAAIQKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211
H ML D R Y N+ K VLD+G+GTGILSMFA KAGA V+ E S +
Sbjct: 86 HEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECS-S 144
Query: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271
+ + + ++ AN ++ I + K ++E+P E+V ++++E + LF E ++ ++I
Sbjct: 145 ISDYSEKIIKANHLDNIITIFKGKVEEVELP---VEKVDIIISEWMGYCLFYESMLNTVI 201
Query: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP- 330
A + L + G + P A ++ +A+E + + +++ G +
Sbjct: 202 FARDKWL------------KPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTC 249
Query: 331 -TNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389
+V + P VD ++ + L + +I TV L +
Sbjct: 250 IRDVAMKEPLVDIVDPKQVVT-------------NACLIKEVDIYTVKTEELSFTSAFC- 295
Query: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEH---SLSTSP-SEETCWEQAVYPVQDLADY 445
+ + + + A++ +F ++ H ST+P + T W+Q V+ ++D
Sbjct: 296 -------LQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLT- 347
Query: 446 WIKPGDHVMMEVSCQDCYLRIQSISVL------GLECEMDVAKSF 484
++ G+ + +S + ++ + G CE V+ +
Sbjct: 348 -VRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDY 391
>gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
Length = 433
Score = 60.5 bits (145), Expect = 6e-09
Identities = 76/302 (25%), Positives = 128/302 (42%), Gaps = 47/302 (15%)
Query: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMF-AKKAGAHSVYACELSK 210
H ML D R T Y++ I Q L K +LD+G GTGI+S+F A A +VYA E S+
Sbjct: 112 HLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASE 171
Query: 211 TMYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESL 270
M + +V N I + K D+ +PE+V ++V+E + L E ++ES+
Sbjct: 172 -MAQHTGQLVLQNGFADIITVYQQKVEDVV----LPEKVDVLVSEWMGTCLLFEFMIESI 226
Query: 271 IHAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP 330
++A A ++ G + P A + V C+ + +
Sbjct: 227 LYA------------RDAWLKEDGVIWPTMAALH--LVPCSADKDYR------------- 259
Query: 331 TNVKFQSPAY----SSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKS 386
+ V F AY S++ + E ++ K + + L+E I+ +D +Q +
Sbjct: 260 SKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQ-ISD 318
Query: 387 LATKKPDKIGIPVIKEGILDAIMVWFVLQLDD------EHSLSTSPSEETC-WEQAVYPV 439
L T + ++ + K G L WF + LST P T W+Q ++ +
Sbjct: 319 LETLR-GELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMM 377
Query: 440 QD 441
D
Sbjct: 378 DD 379
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 750 LSKPVELLRLDLMTPY---LNTSNREVKVYVCKSGRLTAIPFWYHMYLD--------EEI 798
LS+P +L+LD+ T L T E++ + K+G L W+ ++ + +
Sbjct: 300 LSEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVL 359
Query: 799 RLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSI 832
+HWKQ ++D+P+ V G+ + S+
Sbjct: 360 STGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSV 393
>gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
Length = 433
Score = 60.5 bits (145), Expect = 6e-09
Identities = 76/302 (25%), Positives = 128/302 (42%), Gaps = 47/302 (15%)
Query: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMF-AKKAGAHSVYACELSK 210
H ML D R T Y++ I Q L K +LD+G GTGI+S+F A A +VYA E S+
Sbjct: 112 HLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASE 171
Query: 211 TMYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESL 270
M + +V N I + K D+ +PE+V ++V+E + L E ++ES+
Sbjct: 172 -MAQHTGQLVLQNGFADIITVYQQKVEDVV----LPEKVDVLVSEWMGTCLLFEFMIESI 226
Query: 271 IHAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP 330
++A A ++ G + P A + V C+ + +
Sbjct: 227 LYA------------RDAWLKEDGVIWPTMAALH--LVPCSADKDYR------------- 259
Query: 331 TNVKFQSPAY----SSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKS 386
+ V F AY S++ + E ++ K + + L+E I+ +D +Q +
Sbjct: 260 SKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQ-ISD 318
Query: 387 LATKKPDKIGIPVIKEGILDAIMVWFVLQLDD------EHSLSTSPSEETC-WEQAVYPV 439
L T + ++ + K G L WF + LST P T W+Q ++ +
Sbjct: 319 LETLR-GELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMM 377
Query: 440 QD 441
D
Sbjct: 378 DD 379
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 750 LSKPVELLRLDLMTPY---LNTSNREVKVYVCKSGRLTAIPFWYHMYLD--------EEI 798
LS+P +L+LD+ T L T E++ + K+G L W+ ++ + +
Sbjct: 300 LSEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVL 359
Query: 799 RLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSI 832
+HWKQ ++D+P+ V G+ + S+
Sbjct: 360 STGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSV 393
>gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens]
Length = 151
Score = 39.3 bits (90), Expect = 0.015
Identities = 20/48 (41%), Positives = 29/48 (60%)
Query: 90 YEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDA 137
Y A+E+ P+ EV + G L+R+G+ D+A F K + LNP F DA
Sbjct: 81 YTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKKVLDLNPGFQDA 128
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 38.1 bits (87), Expect = 0.034
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 83 IQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKEN 140
I++ + Y +ALE+FP+ +++ L + G EA ++ +A++++P F+DA N
Sbjct: 333 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN 390
Score = 36.2 bits (82), Expect = 0.13
Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 13/168 (7%)
Query: 44 AYAHYLLVLSLAPELKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVI 103
A HY L L P+ F A L A ++ + Y AL+ PD +
Sbjct: 98 AIEHYRHALRLKPD--------FIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCV 149
Query: 104 CNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVANWLVERW---HFIMLNDT 160
+ +G L +G +EA + KA++ P+F+ A N V N E W H T
Sbjct: 150 RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVT 209
Query: 161 KRNTIYNAAIQKAVCLGSKSVLD--IGAGTGILSMFAKKAGAHSVYAC 206
+A I L + D + A LS+ A H AC
Sbjct: 210 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 257
Score = 33.5 bits (75), Expect = 0.85
Identities = 19/67 (28%), Positives = 34/67 (50%)
Query: 74 AEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPD 133
A L ++Q+ L Y++A+ + P ++MG L M A + +A+++NP
Sbjct: 358 ASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA 417
Query: 134 FSDAKEN 140
F+DA N
Sbjct: 418 FADAHSN 424
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 8/94 (8%)
Query: 44 AYAHYLLVLSLAPELKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVI 103
A HY + ++P TF L + +Q L CY +A+++ P
Sbjct: 370 ALMHYKEAIRISP--------TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADA 421
Query: 104 CNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDA 137
+++ G EA + A+KL PDF DA
Sbjct: 422 HSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 455
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 87 LGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVAN 146
+ Y +AL L P+ V+ ++ + G D A + +A++L P F DA + +AN
Sbjct: 235 VAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA---YCNLAN 291
Query: 147 WLVERWHFIMLNDTKRNTIYNAAIQ 171
L E+ D YN A++
Sbjct: 292 ALKEKGSVAEAED-----CYNTALR 311
Score = 31.2 bits (69), Expect = 4.2
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 74 AEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPD 133
A L + + CY AL L P N++ G +EA + KA+++ P+
Sbjct: 290 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 349
Query: 134 FSDAKENFYRV 144
F+ A N V
Sbjct: 350 FAAAHSNLASV 360
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 38.1 bits (87), Expect = 0.034
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 83 IQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKEN 140
I++ + Y +ALE+FP+ +++ L + G EA ++ +A++++P F+DA N
Sbjct: 343 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN 400
Score = 36.2 bits (82), Expect = 0.13
Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 13/168 (7%)
Query: 44 AYAHYLLVLSLAPELKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVI 103
A HY L L P+ F A L A ++ + Y AL+ PD +
Sbjct: 108 AIEHYRHALRLKPD--------FIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCV 159
Query: 104 CNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVANWLVERW---HFIMLNDT 160
+ +G L +G +EA + KA++ P+F+ A N V N E W H T
Sbjct: 160 RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVT 219
Query: 161 KRNTIYNAAIQKAVCLGSKSVLD--IGAGTGILSMFAKKAGAHSVYAC 206
+A I L + D + A LS+ A H AC
Sbjct: 220 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 267
Score = 33.5 bits (75), Expect = 0.85
Identities = 19/67 (28%), Positives = 34/67 (50%)
Query: 74 AEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPD 133
A L ++Q+ L Y++A+ + P ++MG L M A + +A+++NP
Sbjct: 368 ASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA 427
Query: 134 FSDAKEN 140
F+DA N
Sbjct: 428 FADAHSN 434
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 8/94 (8%)
Query: 44 AYAHYLLVLSLAPELKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVI 103
A HY + ++P TF L + +Q L CY +A+++ P
Sbjct: 380 ALMHYKEAIRISP--------TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADA 431
Query: 104 CNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDA 137
+++ G EA + A+KL PDF DA
Sbjct: 432 HSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 465
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 87 LGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVAN 146
+ Y +AL L P+ V+ ++ + G D A + +A++L P F DA + +AN
Sbjct: 245 VAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA---YCNLAN 301
Query: 147 WLVERWHFIMLNDTKRNTIYNAAIQ 171
L E+ D YN A++
Sbjct: 302 ALKEKGSVAEAED-----CYNTALR 321
Score = 31.2 bits (69), Expect = 4.2
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 74 AEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPD 133
A L + + CY AL L P N++ G +EA + KA+++ P+
Sbjct: 300 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 359
Query: 134 FSDAKENFYRV 144
F+ A N V
Sbjct: 360 FAAAHSNLASV 370
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 34.7 bits (78), Expect = 0.38
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 20/127 (15%)
Query: 47 HYLLVLSLAPELKHDVKETFQYTLFRWA-----EELDALSRIQDLLG----------CYE 91
H + +L LK K+ TL + + E DA S + LL Y+
Sbjct: 439 HNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQ 498
Query: 92 QALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRV-----AN 146
++ PD + N+ G L G ++A ++ +A+KL+P A N R+ N
Sbjct: 499 TGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGEN 558
Query: 147 WLVERWH 153
+ E W+
Sbjct: 559 SMAEEWY 565
Score = 30.4 bits (67), Expect = 7.2
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 16/123 (13%)
Query: 90 YEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVANWLV 149
Y++AL+L P ++G L ++EA ++K P+F+DA + +A+ L
Sbjct: 429 YQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADA---YSSLASLLA 485
Query: 150 ERWHFIMLNDTKRNTIYNAAIQKAVCLGSKSVLDIGAGTGILSM---FAKKAGAHSVYAC 206
E+ F + IY I+ C S D+ G+ + +KA AH A
Sbjct: 486 EQERF-----KEAEEIYQTGIKN--CPDSS---DLHNNYGVFLVDTGLPEKAVAHYQQAI 535
Query: 207 ELS 209
+LS
Sbjct: 536 KLS 538
>gi|20270349 MIT, microtubule interacting and transport, domain
containing 1 [Homo sapiens]
Length = 249
Score = 33.5 bits (75), Expect = 0.85
Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 58 LKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFR 117
L+ D + T T+ + A ELD+ SR L CY++ ++L + ++ R R
Sbjct: 6 LRQDPQSTAAATVLKRAVELDSESRYPQALVCYQEGIDLLLQ---VLKGTKDNTKRCNLR 62
Query: 118 DEAAGYFHKAVKLNPDFSDAKEN 140
++ + Y +A + KE+
Sbjct: 63 EKISKYMDRAENIKKYLDQEKED 85
>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 11 DAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTL 70
+ G G G + + SL S L V++ A A L S+ P+++ + L
Sbjct: 444 EEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLA-AVRLDPTSIDPDVQCGLG-----VL 497
Query: 71 FRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKL 130
F + E D + C+ AL + P+D ++ N +G L +EA + +A++L
Sbjct: 498 FNLSGEYDKA------VDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 551
Query: 131 NPDFSDAKEN 140
P + ++ N
Sbjct: 552 QPGYIRSRYN 561
>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 11 DAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTL 70
+ G G G + + SL S L V++ A A L S+ P+++ + L
Sbjct: 444 EEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLA-AVRLDPTSIDPDVQCGLG-----VL 497
Query: 71 FRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKL 130
F + E D + C+ AL + P+D ++ N +G L +EA + +A++L
Sbjct: 498 FNLSGEYDKA------VDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 551
Query: 131 NPDFSDAKEN 140
P + ++ N
Sbjct: 552 QPGYIRSRYN 561
>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo
sapiens]
Length = 602
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 11 DAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTL 70
+ G G G + + SL S L V++ A A L S+ P+++ + L
Sbjct: 407 EEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLA-AVRLDPTSIDPDVQCGLG-----VL 460
Query: 71 FRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKL 130
F + E D + C+ AL + P+D ++ N +G L +EA + +A++L
Sbjct: 461 FNLSGEYDKA------VDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 514
Query: 131 NPDFSDAKEN 140
P + ++ N
Sbjct: 515 QPGYIRSRYN 524
>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo
sapiens]
Length = 654
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 11 DAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTL 70
+ G G G + + SL S L V++ A A L S+ P+++ + L
Sbjct: 459 EEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLA-AVRLDPTSIDPDVQCGLG-----VL 512
Query: 71 FRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKL 130
F + E D + C+ AL + P+D ++ N +G L +EA + +A++L
Sbjct: 513 FNLSGEYDKA------VDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 566
Query: 131 NPDFSDAKEN 140
P + ++ N
Sbjct: 567 QPGYIRSRYN 576
>gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo
sapiens]
Length = 631
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 11 DAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTL 70
+ G G G + + SL S L V++ A A L S+ P+++ + L
Sbjct: 436 EEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLA-AVRLDPTSIDPDVQCGLG-----VL 489
Query: 71 FRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKL 130
F + E D + C+ AL + P+D ++ N +G L +EA + +A++L
Sbjct: 490 FNLSGEYDKA------VDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 543
Query: 131 NPDFSDAKEN 140
P + ++ N
Sbjct: 544 QPGYIRSRYN 553
>gi|239756067 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 157
Score = 32.0 bits (71), Expect = 2.5
Identities = 37/146 (25%), Positives = 63/146 (43%), Gaps = 19/146 (13%)
Query: 126 KAVKLNPDFSDAKEN----------FYRVANWLVERWHFIMLNDTKRNTIYNAAIQ--KA 173
K ++P+ DAK+ V LV+R + + D + T A+Q +
Sbjct: 3 KKTTMDPNIRDAKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQRE 62
Query: 174 VCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLH 233
VC + ++D GA I+ ++ A ++VY LS L+C K +AG H
Sbjct: 63 VC--ANILIDSGADPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAG----H 116
Query: 234 TKSLDIEIPKHIPERVSLVVTETVDA 259
T L + I K + V ++T+ +A
Sbjct: 117 TPLL-LAIRKRSEQIVEFLLTKNANA 141
>gi|239744894 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 197
Score = 32.0 bits (71), Expect = 2.5
Identities = 37/146 (25%), Positives = 63/146 (43%), Gaps = 19/146 (13%)
Query: 126 KAVKLNPDFSDAKEN----------FYRVANWLVERWHFIMLNDTKRNTIYNAAIQ--KA 173
K ++P+ DAK+ V LV+R + + D + T A+Q +
Sbjct: 3 KKTTMDPNIRDAKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQRE 62
Query: 174 VCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLH 233
VC + ++D GA I+ ++ A ++VY LS L+C K +AG H
Sbjct: 63 VC--ANILIDSGADPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAG----H 116
Query: 234 TKSLDIEIPKHIPERVSLVVTETVDA 259
T L + I K + V ++T+ +A
Sbjct: 117 TPLL-LAIRKRSEQIVEFLLTKNANA 141
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 31.6 bits (70), Expect = 3.2
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 630 KETLEFWLRHVEDESAMLQRPKSDKLWSIIILDVIEPSGLIQQEIMEKAAISRCLLQSGG 689
K+ E E +RP+ D+L + D I+ G++Q++I EK+ + Q G
Sbjct: 317 KQMAELLRSSCPQERLQQERPQLDRL-KTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGS 375
Query: 690 KIFPQYVLMFGLLVESQTLL--EENAVQGTERTL 721
K PQ F L + + + +N QG E+ L
Sbjct: 376 KQSPQ--APFAELADDEKVFNGSDNMWQGQEQAL 407
>gi|34222104 hypothetical protein LOC26074 [Homo sapiens]
Length = 1237
Score = 30.8 bits (68), Expect = 5.5
Identities = 19/73 (26%), Positives = 34/73 (46%)
Query: 652 SDKLWSIIILDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGLLVESQTLLEE 711
SDK + +I L + P + Q ++ + C L+ +F + L+ + + TLL+
Sbjct: 415 SDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKSINIRFATLLDT 474
Query: 712 NAVQGTERTLGLN 724
V+ TL LN
Sbjct: 475 PGVENLVSTLMLN 487
>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
sapiens]
Length = 2644
Score = 30.4 bits (67), Expect = 7.2
Identities = 18/81 (22%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 76 ELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFS 135
E ++L ++D CY++A++L PD + + + + + +G + +++
Sbjct: 1708 EHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWT 1767
Query: 136 DAKENFYRV-ANWLVERWHFI 155
D + N YRV A W + +W +
Sbjct: 1768 D-ELNTYRVEAAWKLSQWDLV 1787
>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 2105
Score = 30.4 bits (67), Expect = 7.2
Identities = 18/81 (22%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 76 ELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFS 135
E ++L ++D CY++A++L PD + + + + + +G + +++
Sbjct: 1466 EHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWT 1525
Query: 136 DAKENFYRV-ANWLVERWHFI 155
D + N YRV A W + +W +
Sbjct: 1526 D-ELNTYRVEAAWKLSQWDLV 1545
>gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
Length = 758
Score = 30.0 bits (66), Expect = 9.4
Identities = 16/78 (20%), Positives = 38/78 (48%)
Query: 64 ETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGY 123
+ + +L R ++ L ++ L ++ ++LFP+D + N +G +G D A
Sbjct: 417 DLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKV 476
Query: 124 FHKAVKLNPDFSDAKENF 141
+ + + + P+ AK ++
Sbjct: 477 YEEVLSVTPNDGFAKVHY 494
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,225,081
Number of Sequences: 37866
Number of extensions: 1303448
Number of successful extensions: 3342
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3263
Number of HSP's gapped (non-prelim): 66
length of query: 845
length of database: 18,247,518
effective HSP length: 111
effective length of query: 734
effective length of database: 14,044,392
effective search space: 10308583728
effective search space used: 10308583728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.