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Search of human proteins with 40254464
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254464 leptin receptor isoform 1 [Homo sapiens]
(1165 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 2413 0.0
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 1863 0.0
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 1863 0.0
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 103 1e-21
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 80 1e-14
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 80 1e-14
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 80 1e-14
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 80 1e-14
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 74 6e-13
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 74 6e-13
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 67 8e-11
gi|4557040 oncostatin M receptor [Homo sapiens] 62 2e-09
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 62 3e-09
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 61 7e-09
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 58 5e-08
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 56 2e-07
gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom... 53 1e-06
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 51 6e-06
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 51 6e-06
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 51 6e-06
gi|4506107 prolactin receptor [Homo sapiens] 45 4e-04
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 44 0.001
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 44 0.001
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 44 0.001
gi|4885491 myeloproliferative leukemia virus oncogene precursor ... 41 0.006
gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo sap... 41 0.006
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 41 0.008
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 41 0.008
gi|24430212 interleukin 23 receptor precursor [Homo sapiens] 40 0.013
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 40 0.013
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 2413 bits (6254), Expect = 0.0
Identities = 1165/1165 (100%), Positives = 1165/1165 (100%)
Query: 1 MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS 60
MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS
Sbjct: 1 MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS 60
Query: 61 NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF 120
NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF
Sbjct: 61 NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF 120
Query: 121 QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS 180
QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS
Sbjct: 121 QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS 180
Query: 181 FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP 240
FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP
Sbjct: 181 FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP 240
Query: 241 LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP 300
LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP
Sbjct: 241 LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP 300
Query: 301 GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI 360
GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI
Sbjct: 301 GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI 360
Query: 361 VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH 420
VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH
Sbjct: 361 VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH 420
Query: 421 RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH 480
RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH
Sbjct: 421 RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH 480
Query: 481 PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP 540
PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP
Sbjct: 481 PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP 540
Query: 541 SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV 600
SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV
Sbjct: 541 SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV 600
Query: 601 PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV 660
PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV
Sbjct: 601 PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV 660
Query: 661 TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI 720
TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI
Sbjct: 661 TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI 720
Query: 721 GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED 780
GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED
Sbjct: 721 GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED 780
Query: 781 GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA 840
GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA
Sbjct: 781 GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA 840
Query: 841 GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFI 900
GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFI
Sbjct: 841 GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFI 900
Query: 901 KHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFN 960
KHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFN
Sbjct: 901 KHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFN 960
Query: 961 SVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPL 1020
SVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPL
Sbjct: 961 SVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPL 1020
Query: 1021 KDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYL 1080
KDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYL
Sbjct: 1021 KDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYL 1080
Query: 1081 GVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFAS 1140
GVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFAS
Sbjct: 1081 GVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFAS 1140
Query: 1141 YMPQFQTCSTQTHKIMENKMCDLTV 1165
YMPQFQTCSTQTHKIMENKMCDLTV
Sbjct: 1141 YMPQFQTCSTQTHKIMENKMCDLTV 1165
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 1863 bits (4826), Expect = 0.0
Identities = 891/891 (100%), Positives = 891/891 (100%)
Query: 1 MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS 60
MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS
Sbjct: 1 MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS 60
Query: 61 NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF 120
NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF
Sbjct: 61 NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF 120
Query: 121 QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS 180
QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS
Sbjct: 121 QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS 180
Query: 181 FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP 240
FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP
Sbjct: 181 FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP 240
Query: 241 LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP 300
LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP
Sbjct: 241 LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP 300
Query: 301 GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI 360
GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI
Sbjct: 301 GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI 360
Query: 361 VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH 420
VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH
Sbjct: 361 VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH 420
Query: 421 RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH 480
RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH
Sbjct: 421 RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH 480
Query: 481 PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP 540
PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP
Sbjct: 481 PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP 540
Query: 541 SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV 600
SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV
Sbjct: 541 SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV 600
Query: 601 PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV 660
PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV
Sbjct: 601 PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV 660
Query: 661 TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI 720
TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI
Sbjct: 661 TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI 720
Query: 721 GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED 780
GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED
Sbjct: 721 GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED 780
Query: 781 GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA 840
GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA
Sbjct: 781 GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA 840
Query: 841 GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQK 891
GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQK
Sbjct: 841 GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQK 891
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 1863 bits (4826), Expect = 0.0
Identities = 891/891 (100%), Positives = 891/891 (100%)
Query: 1 MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS 60
MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS
Sbjct: 1 MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS 60
Query: 61 NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF 120
NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF
Sbjct: 61 NGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF 120
Query: 121 QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS 180
QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS
Sbjct: 121 QQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGS 180
Query: 181 FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP 240
FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP
Sbjct: 181 FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP 240
Query: 241 LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP 300
LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP
Sbjct: 241 LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP 300
Query: 301 GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI 360
GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI
Sbjct: 301 GSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKI 360
Query: 361 VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH 420
VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH
Sbjct: 361 VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH 420
Query: 421 RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH 480
RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH
Sbjct: 421 RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH 480
Query: 481 PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP 540
PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP
Sbjct: 481 PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP 540
Query: 541 SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV 600
SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV
Sbjct: 541 SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV 600
Query: 601 PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV 660
PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV
Sbjct: 601 PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV 660
Query: 661 TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI 720
TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI
Sbjct: 661 TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI 720
Query: 721 GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED 780
GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED
Sbjct: 721 GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED 780
Query: 781 GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA 840
GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA
Sbjct: 781 GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA 840
Query: 841 GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQK 891
GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQK
Sbjct: 841 GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQK 891
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 103 bits (257), Expect = 1e-21
Identities = 114/510 (22%), Positives = 202/510 (39%), Gaps = 47/510 (9%)
Query: 337 PPKILTSVGSNVSFHCIYKKENKI---VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393
P + + SN + C+ K++ V + IVW N IP+ QY +++ S VTF
Sbjct: 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFT-IPKEQYTIINRTASSVTF 91
Query: 394 FNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLT-------KMT 446
++ + + CN +Y I + + E L+ KM
Sbjct: 92 TDIA--------SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
Query: 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECI--FQPIF 504
C W E+ L+ + S + + H + DC + D C + ++
Sbjct: 144 CEWDGGR-----ETHLETNFTLKSEWAT-----HKFA---DCKAKRDTPTSCTVDYSTVY 190
Query: 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIG-LLKISWEKPVF 563
++ +W+ ++LG + S P VKP PP ++ + + +LK++W P
Sbjct: 191 FVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
Query: 564 PENN-LQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--CAVYAVQVRCKRLDGLG 620
L++ I+Y W D S S V DL Y ++RC + DG G
Sbjct: 250 KSVIILKYNIQYRTKDAST-WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
Query: 621 YWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYV 680
YWS+WS A + + + P + P FW I+ + + V L+WK L ++ + Y
Sbjct: 309 YWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
Query: 681 INHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNI 740
+ T N TK T T + T+ N +G S A + +
Sbjct: 368 VT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
Query: 741 VQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGE--IKWLRISSSVKKYYIH 798
V L A+P + + V W K +I+EW L++ W + +V + Y+
Sbjct: 427 VMDLKAFP-KDNMLWVEWTTPRESVK--KYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
Query: 799 DHFIPIEKYQFSLYPIFMEGVGKPKIINSF 828
+ + Y ++ P++ +G G P+ I ++
Sbjct: 484 GNLAESKCYLITVTPVYADGPGSPESIKAY 513
Score = 52.0 bits (123), Expect = 3e-06
Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 15/117 (12%)
Query: 214 KITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGN--LKISWSSPPL-----VPFP 266
K+TS + F P+ VKP+PP L + +++ + LK++W++P + + +
Sbjct: 206 KVTSDHINFD-------PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
Query: 267 LQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
+QY+ K + + + E D + +S V + P + Y ++R + DG G WSDWS
Sbjct: 259 IQYRTKDASTWSQIPPE-DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 79.7 bits (195), Expect = 1e-14
Identities = 111/531 (20%), Positives = 206/531 (38%), Gaps = 59/531 (11%)
Query: 341 LTSVGSNVSFHCIYKKE-NKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSK--VTFFNLN 397
+ +G ++ CI K+ + + P +I+W + AE P + +SD + +T +LN
Sbjct: 35 IVHLGDPITASCIIKQNCSHLDPEPQILWRLG-AELQPGGRQQRLSDGTQESIITLPHLN 93
Query: 398 ETKPRGKFTYDAVYCCNEHECHHRYAELYVID-----------VNINISCETDGYLTKMT 446
T+ A C C + L ++D + N+SC + + +
Sbjct: 94 HTQ--------AFLSC----CLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLI 141
Query: 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIF--QPIF 504
C+W L S L+ +S C DC + DG C + +
Sbjct: 142 CQWEPGPETHLPTS-FTLKSFKSRGNCQTQGD-----SILDC-VPKDGQSHCCIPRKHLL 194
Query: 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP-----SSVKAEITINIGLLKISWE 559
L +W++ ++LG+ SP C+ P VVK PP G L++ WE
Sbjct: 195 LYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE 254
Query: 560 KPVFP--ENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLD 617
P P N + ++R+ E W + ++ L Y +Q+RC R
Sbjct: 255 -PWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWP 313
Query: 618 GLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQ 677
G+WS+WS + +R +WR + V L WKP+ + +Q
Sbjct: 314 LPGHWSDWSPSLELRTTERAPTVRLDTWWR----QRQLDPRTVQLFWKPVPLEEDSGRIQ 369
Query: 678 RYVINHHTSCNGTWSEDVGNHTKF--TFLWTEQAHTVTVLAINSIGASVANFNLTFSWPM 735
YV++ S + N T+ TF +A V ++A NS G S + FS
Sbjct: 370 GYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT-PVVFS--E 426
Query: 736 SKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEW----KNLNEDGEIKWLRISSS 791
S+ + L A + + V W P + ++IEW + + + + +
Sbjct: 427 SRGPALTRLHAMARDPHSLWVGW--EPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGR 484
Query: 792 VKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGL 842
+ + ++ P + Y+ + P++ + +G + + +++Q+ H + L
Sbjct: 485 ATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHL 535
Score = 38.9 bits (89), Expect = 0.029
Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 224 SPLMSVQPINMVKPDPPLGLHMEITDD------GNLKISWSSPPLVP-------FPLQYQ 270
SP + + P+++VK +PP+ M+ + + G L++ W P P L+++
Sbjct: 214 SPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE--PWQPGLHINQKCELRHK 271
Query: 271 VKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
+ E S ++ + A + +LP ++Y +Q+R R PG WSDWS
Sbjct: 272 PQRGEASWALVGPLP--LEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 79.7 bits (195), Expect = 1e-14
Identities = 111/531 (20%), Positives = 206/531 (38%), Gaps = 59/531 (11%)
Query: 341 LTSVGSNVSFHCIYKKE-NKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSK--VTFFNLN 397
+ +G ++ CI K+ + + P +I+W + AE P + +SD + +T +LN
Sbjct: 35 IVHLGDPITASCIIKQNCSHLDPEPQILWRLG-AELQPGGRQQRLSDGTQESIITLPHLN 93
Query: 398 ETKPRGKFTYDAVYCCNEHECHHRYAELYVID-----------VNINISCETDGYLTKMT 446
T+ A C C + L ++D + N+SC + + +
Sbjct: 94 HTQ--------AFLSC----CLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLI 141
Query: 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIF--QPIF 504
C+W L S L+ +S C DC + DG C + +
Sbjct: 142 CQWEPGPETHLPTS-FTLKSFKSRGNCQTQGD-----SILDC-VPKDGQSHCCIPRKHLL 194
Query: 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP-----SSVKAEITINIGLLKISWE 559
L +W++ ++LG+ SP C+ P VVK PP G L++ WE
Sbjct: 195 LYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE 254
Query: 560 KPVFP--ENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLD 617
P P N + ++R+ E W + ++ L Y +Q+RC R
Sbjct: 255 -PWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWP 313
Query: 618 GLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQ 677
G+WS+WS + +R +WR + V L WKP+ + +Q
Sbjct: 314 LPGHWSDWSPSLELRTTERAPTVRLDTWWR----QRQLDPRTVQLFWKPVPLEEDSGRIQ 369
Query: 678 RYVINHHTSCNGTWSEDVGNHTKF--TFLWTEQAHTVTVLAINSIGASVANFNLTFSWPM 735
YV++ S + N T+ TF +A V ++A NS G S + FS
Sbjct: 370 GYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT-PVVFS--E 426
Query: 736 SKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEW----KNLNEDGEIKWLRISSS 791
S+ + L A + + V W P + ++IEW + + + + +
Sbjct: 427 SRGPALTRLHAMARDPHSLWVGW--EPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGR 484
Query: 792 VKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGL 842
+ + ++ P + Y+ + P++ + +G + + +++Q+ H + L
Sbjct: 485 ATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHL 535
Score = 38.9 bits (89), Expect = 0.029
Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 224 SPLMSVQPINMVKPDPPLGLHMEITDD------GNLKISWSSPPLVP-------FPLQYQ 270
SP + + P+++VK +PP+ M+ + + G L++ W P P L+++
Sbjct: 214 SPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE--PWQPGLHINQKCELRHK 271
Query: 271 VKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
+ E S ++ + A + +LP ++Y +Q+R R PG WSDWS
Sbjct: 272 PQRGEASWALVGPLP--LEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 79.7 bits (195), Expect = 1e-14
Identities = 111/531 (20%), Positives = 206/531 (38%), Gaps = 59/531 (11%)
Query: 341 LTSVGSNVSFHCIYKKE-NKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSK--VTFFNLN 397
+ +G ++ CI K+ + + P +I+W + AE P + +SD + +T +LN
Sbjct: 35 IVHLGDPITASCIIKQNCSHLDPEPQILWRLG-AELQPGGRQQRLSDGTQESIITLPHLN 93
Query: 398 ETKPRGKFTYDAVYCCNEHECHHRYAELYVID-----------VNINISCETDGYLTKMT 446
T+ A C C + L ++D + N+SC + + +
Sbjct: 94 HTQ--------AFLSC----CLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLI 141
Query: 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIF--QPIF 504
C+W L S L+ +S C DC + DG C + +
Sbjct: 142 CQWEPGPETHLPTS-FTLKSFKSRGNCQTQGD-----SILDC-VPKDGQSHCCIPRKHLL 194
Query: 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP-----SSVKAEITINIGLLKISWE 559
L +W++ ++LG+ SP C+ P VVK PP G L++ WE
Sbjct: 195 LYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE 254
Query: 560 KPVFP--ENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLD 617
P P N + ++R+ E W + ++ L Y +Q+RC R
Sbjct: 255 -PWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWP 313
Query: 618 GLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQ 677
G+WS+WS + +R +WR + V L WKP+ + +Q
Sbjct: 314 LPGHWSDWSPSLELRTTERAPTVRLDTWWR----QRQLDPRTVQLFWKPVPLEEDSGRIQ 369
Query: 678 RYVINHHTSCNGTWSEDVGNHTKF--TFLWTEQAHTVTVLAINSIGASVANFNLTFSWPM 735
YV++ S + N T+ TF +A V ++A NS G S + FS
Sbjct: 370 GYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT-PVVFS--E 426
Query: 736 SKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEW----KNLNEDGEIKWLRISSS 791
S+ + L A + + V W P + ++IEW + + + + +
Sbjct: 427 SRGPALTRLHAMARDPHSLWVGW--EPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGR 484
Query: 792 VKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGL 842
+ + ++ P + Y+ + P++ + +G + + +++Q+ H + L
Sbjct: 485 ATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHL 535
Score = 38.9 bits (89), Expect = 0.029
Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 224 SPLMSVQPINMVKPDPPLGLHMEITDD------GNLKISWSSPPLVP-------FPLQYQ 270
SP + + P+++VK +PP+ M+ + + G L++ W P P L+++
Sbjct: 214 SPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE--PWQPGLHINQKCELRHK 271
Query: 271 VKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
+ E S ++ + A + +LP ++Y +Q+R R PG WSDWS
Sbjct: 272 PQRGEASWALVGPLP--LEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 79.7 bits (195), Expect = 1e-14
Identities = 111/531 (20%), Positives = 206/531 (38%), Gaps = 59/531 (11%)
Query: 341 LTSVGSNVSFHCIYKKE-NKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSK--VTFFNLN 397
+ +G ++ CI K+ + + P +I+W + AE P + +SD + +T +LN
Sbjct: 35 IVHLGDPITASCIIKQNCSHLDPEPQILWRLG-AELQPGGRQQRLSDGTQESIITLPHLN 93
Query: 398 ETKPRGKFTYDAVYCCNEHECHHRYAELYVID-----------VNINISCETDGYLTKMT 446
T+ A C C + L ++D + N+SC + + +
Sbjct: 94 HTQ--------AFLSC----CLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLI 141
Query: 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIF--QPIF 504
C+W L S L+ +S C DC + DG C + +
Sbjct: 142 CQWEPGPETHLPTS-FTLKSFKSRGNCQTQGD-----SILDC-VPKDGQSHCCIPRKHLL 194
Query: 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP-----SSVKAEITINIGLLKISWE 559
L +W++ ++LG+ SP C+ P VVK PP G L++ WE
Sbjct: 195 LYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE 254
Query: 560 KPVFP--ENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLD 617
P P N + ++R+ E W + ++ L Y +Q+RC R
Sbjct: 255 -PWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWP 313
Query: 618 GLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQ 677
G+WS+WS + +R +WR + V L WKP+ + +Q
Sbjct: 314 LPGHWSDWSPSLELRTTERAPTVRLDTWWR----QRQLDPRTVQLFWKPVPLEEDSGRIQ 369
Query: 678 RYVINHHTSCNGTWSEDVGNHTKF--TFLWTEQAHTVTVLAINSIGASVANFNLTFSWPM 735
YV++ S + N T+ TF +A V ++A NS G S + FS
Sbjct: 370 GYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT-PVVFS--E 426
Query: 736 SKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEW----KNLNEDGEIKWLRISSS 791
S+ + L A + + V W P + ++IEW + + + + +
Sbjct: 427 SRGPALTRLHAMARDPHSLWVGW--EPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGR 484
Query: 792 VKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGL 842
+ + ++ P + Y+ + P++ + +G + + +++Q+ H + L
Sbjct: 485 ATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHL 535
Score = 38.9 bits (89), Expect = 0.029
Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 224 SPLMSVQPINMVKPDPPLGLHMEITDD------GNLKISWSSPPLVP-------FPLQYQ 270
SP + + P+++VK +PP+ M+ + + G L++ W P P L+++
Sbjct: 214 SPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWE--PWQPGLHINQKCELRHK 271
Query: 271 VKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
+ E S ++ + A + +LP ++Y +Q+R R PG WSDWS
Sbjct: 272 PQRGEASWALVGPLP--LEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 74.3 bits (181), Expect = 6e-13
Identities = 108/508 (21%), Positives = 210/508 (41%), Gaps = 54/508 (10%)
Query: 319 WSDWSTPRVFT---TQDVIYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEK 375
WSDWS + + FP + VGS+++F C+ + K++ + ++ N
Sbjct: 235 WSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCV--SQEKVLSA--LIGHTNC--- 287
Query: 376 IPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINIS 435
P D ++V+ + N++ + G + V+ ++ Y D ++
Sbjct: 288 -PLIHLD--GENVA-IKIRNISVSASSGT---NVVFTTEDNIFGTVIFAGYPPDTPQQLN 340
Query: 436 CETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGF 495
CET L ++ C W+ + +L R++ Y K ++
Sbjct: 341 CETHD-LKEIICSWNPGRVTALVGP-------RATSYTLVESFSGKYVRLKRAEAPTNES 392
Query: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Y+ +FQ + Y + ++ LG S + + V P P+S K + IN +K
Sbjct: 393 YQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVY-PHTPTSFKVK-DINSTAVK 450
Query: 556 ISWEKPV-FPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKS--VSLPVPDLCAVYAVQVR 612
+SW P F + N +I S + + + ++ S V+L + +Y ++R
Sbjct: 451 LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIR 510
Query: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDS 672
C + WS WSN + + P +GP+ WR + D KN+ + WKPL N++
Sbjct: 511 CST-ETFWKWSKWSNKKQHLTTEAS-PSKGPDTWREWSSDG----KNLIIYWKPLPINEA 564
Query: 673 LCSVQRYVINHHTSCNG-----TWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANF 727
+++++ SC+ + SE K + + ++V+A NS+G+S +
Sbjct: 565 ----NGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSK 620
Query: 728 NLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKN--LNEDGEIKW 785
+ P + I Q + ++++W P+ ++I+W N +E + W
Sbjct: 621 IASMEIPNDDLKIEQVVGM----GKGILLTWHYDPN--MTCDYVIKWCNSSRSEPCLMDW 674
Query: 786 LRI-SSSVKKYYIHDHFIPIEKYQFSLY 812
++ S+S + D F P +Y F LY
Sbjct: 675 RKVPSNSTETVIESDEFRPGIRYNFFLY 702
Score = 35.4 bits (80), Expect = 0.32
Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 13/78 (16%)
Query: 818 GVGKPKIINSFTQDDIEKHQSDAGLYV--IVPVIISSSILLLGTLLISHQR--MKKLFWE 873
GVG K + T+++ GL + ++PV ++ + ++ ++L +R +K+ F+
Sbjct: 818 GVGPEKSMYVVTKEN------SVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYP 871
Query: 874 DVPNPKNCSWAQGLNFQK 891
D+PNP+NC + L FQK
Sbjct: 872 DIPNPENC---KALQFQK 886
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 74.3 bits (181), Expect = 6e-13
Identities = 108/508 (21%), Positives = 210/508 (41%), Gaps = 54/508 (10%)
Query: 319 WSDWSTPRVFT---TQDVIYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEK 375
WSDWS + + FP + VGS+++F C+ + K++ + ++ N
Sbjct: 235 WSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCV--SQEKVLSA--LIGHTNC--- 287
Query: 376 IPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINIS 435
P D ++V+ + N++ + G + V+ ++ Y D ++
Sbjct: 288 -PLIHLD--GENVA-IKIRNISVSASSGT---NVVFTTEDNIFGTVIFAGYPPDTPQQLN 340
Query: 436 CETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGF 495
CET L ++ C W+ + +L R++ Y K ++
Sbjct: 341 CETHD-LKEIICSWNPGRVTALVGP-------RATSYTLVESFSGKYVRLKRAEAPTNES 392
Query: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Y+ +FQ + Y + ++ LG S + + V P P+S K + IN +K
Sbjct: 393 YQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVY-PHTPTSFKVK-DINSTAVK 450
Query: 556 ISWEKPV-FPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKS--VSLPVPDLCAVYAVQVR 612
+SW P F + N +I S + + + ++ S V+L + +Y ++R
Sbjct: 451 LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIR 510
Query: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDS 672
C + WS WSN + + P +GP+ WR + D KN+ + WKPL N++
Sbjct: 511 CST-ETFWKWSKWSNKKQHLTTEAS-PSKGPDTWREWSSDG----KNLIIYWKPLPINEA 564
Query: 673 LCSVQRYVINHHTSCNG-----TWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANF 727
+++++ SC+ + SE K + + ++V+A NS+G+S +
Sbjct: 565 ----NGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSK 620
Query: 728 NLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKN--LNEDGEIKW 785
+ P + I Q + ++++W P+ ++I+W N +E + W
Sbjct: 621 IASMEIPNDDLKIEQVVGM----GKGILLTWHYDPN--MTCDYVIKWCNSSRSEPCLMDW 674
Query: 786 LRI-SSSVKKYYIHDHFIPIEKYQFSLY 812
++ S+S + D F P +Y F LY
Sbjct: 675 RKVPSNSTETVIESDEFRPGIRYNFFLY 702
Score = 35.4 bits (80), Expect = 0.32
Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 13/78 (16%)
Query: 818 GVGKPKIINSFTQDDIEKHQSDAGLYV--IVPVIISSSILLLGTLLISHQR--MKKLFWE 873
GVG K + T+++ GL + ++PV ++ + ++ ++L +R +K+ F+
Sbjct: 818 GVGPEKSMYVVTKEN------SVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYP 871
Query: 874 DVPNPKNCSWAQGLNFQK 891
D+PNP+NC + L FQK
Sbjct: 872 DIPNPENC---KALQFQK 886
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 67.4 bits (163), Expect = 8e-11
Identities = 87/419 (20%), Positives = 165/419 (39%), Gaps = 43/419 (10%)
Query: 433 NISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQS 492
NISC Y +TC WS S + T++ Y + + + C
Sbjct: 59 NISC-VYYYRKNLTCTWSPGKETSYTQYTVKRTYAFGEKHDNCTTNSSTSENRASC---- 113
Query: 493 DGFYECIFQP-IFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINI 551
F P I + YT+ + + G + S T +++ K PP + + + I
Sbjct: 114 -----SFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGI 168
Query: 552 G-LLKISWEKPVFP--ENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--CAV 606
+++I W KP ++L++ +R+ ++ + K K+ + + L
Sbjct: 169 KRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTE 228
Query: 607 YAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKP 666
Y + +RC + +WS+WS + + + P G E WR++ + V LLWK
Sbjct: 229 YVIALRCAVKESK-FWSDWSQEKMGMTEE-EAPC-GLELWRVLKPAEADGRRPVRLLWKK 285
Query: 667 LMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTE-QAHTVTVLAINSIGASVA 725
L Y I ++ N +E + + L ++ V++++ NS+G S
Sbjct: 286 ARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQQLELHLGGESFWVSMISYNSLGKS-- 343
Query: 726 NFNLTFSWPMSKVNIV----QSLSAYPLNSSCV-----IVSWILSPSDYKLMYFIIEW-- 774
P++ + I +S + +CV +V W S D ++IEW
Sbjct: 344 --------PVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQSSALDVNT--WMIEWFP 393
Query: 775 KNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDI 833
+E + W +S + D P Y S+YP+ + VG+P I ++ ++ +
Sbjct: 394 DVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVGEPYSIQAYAKEGV 452
Score = 31.6 bits (70), Expect = 4.6
Identities = 45/224 (20%), Positives = 91/224 (40%), Gaps = 20/224 (8%)
Query: 127 WNIQCWLKGDL-KLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPL---VPQKGSFQ 182
W W+ L K + + + +N+ Y Y+ +L E S V + +F
Sbjct: 35 WTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSYTQYTVKRTYAFG 94
Query: 183 MVHCNCSVHEC-----CECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKP 237
H NC+ + C +P + D + ++ +G + +S + + N+ K
Sbjct: 95 EKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKT 154
Query: 238 DPPLGLHME--ITDDGNLKISWSSPPLVPFP--LQYQVKYSENSTTVIREAD-----KIV 288
+PP ++ + ++I W P L P L+Y +++ ++T E + K
Sbjct: 155 EPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDK 214
Query: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQD 332
+ T L + P + Y + +R + WSDWS ++ T++
Sbjct: 215 NQTYNLT-GLQPFTEYVIALRCAVKESK-FWSDWSQEKMGMTEE 256
>gi|4557040 oncostatin M receptor [Homo sapiens]
Length = 979
Score = 62.4 bits (150), Expect = 2e-09
Identities = 113/517 (21%), Positives = 198/517 (38%), Gaps = 60/517 (11%)
Query: 316 PGIWSDWSTPRVFTTQD------VIYFPPKILTSVGSNVSFHCIYKK-ENKIVPSKEIVW 368
P WS+WS+ + QD + FP L G+NV+ + + +N + E
Sbjct: 126 PNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLE--- 182
Query: 369 WMNLAEKIPQSQYDVVSDHVSKVTFFNLNETK-PRGKFTYDAVYC-CNEHECHHRYAELY 426
++I Q D VT FNLN R K T +YC ++ +
Sbjct: 183 ----GKQIHGEQLD------PHVTAFNLNSVPFIRNKGTN--IYCEASQGNVSEGMKGIV 230
Query: 427 -----VIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481
V++ + SCET+ + T + C W T +L S + + +L+ S
Sbjct: 231 LFVSKVLEEPKDFSCETEDFKT-LHCTWDPGTDTALGWSKQPSQSY--TLFESFSGEKKL 287
Query: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPS 541
+ C Q + + + Y +N V + P
Sbjct: 288 CTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHR----------VYLMNPF 337
Query: 542 SVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVP 601
SV E +N ++W+ NN + + L G E + Y V + L
Sbjct: 338 SVNFE-NVNATNAIMTWKVHSI-RNNFTYLCQIELHG-EGKMMQYNVSIKVNGEYFLSEL 394
Query: 602 DLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVT 661
+ Y +VRC WS WS +T + P P+ WRI++ + VT
Sbjct: 395 EPATEYMARVRCADASHFWKWSEWSGQNFTTLE--AAPSEAPDVWRIVSLE--PGNHTVT 450
Query: 662 LLWKPLMKNDSLCSVQRY--VINHHTSCNGTWSEDVGNHTKFTFLWTEQ-AHTVTVLAIN 718
L WKPL K + + Y V+ + + + + T L ++ ++ + V+A N
Sbjct: 451 LFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANN 510
Query: 719 SIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLN 778
S+GAS A+ + + P +K + ++ S +SW P D ++ ++++W +
Sbjct: 511 SVGASPASVIVISADPENKEVEEERIAGTEGGFS---LSWKPQPGD--VIGYVVDWCDHT 565
Query: 779 ED--GEIKWLRISSSVKKYYIH-DHFIPIEKYQFSLY 812
+D G+ +W + + I D F P +Y F +Y
Sbjct: 566 QDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIY 602
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 62.0 bits (149), Expect = 3e-09
Identities = 72/309 (23%), Positives = 122/309 (39%), Gaps = 40/309 (12%)
Query: 337 PPKILTSVGSNVSFHCIYKKENKI---VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393
P + + SN + C+ K++ V + IVW N IP+ QY +++ S VTF
Sbjct: 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFT-IPKEQYTIINRTASSVTF 91
Query: 394 FNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLT-------KMT 446
++ + + CN +Y I + + E L+ KM
Sbjct: 92 TDIA--------SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
Query: 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECI--FQPIF 504
C W E+ L+ + S + + H + DC + D C + ++
Sbjct: 144 CEWDGGR-----ETHLETNFTLKSEWAT-----HKFA---DCKAKRDTPTSCTVDYSTVY 190
Query: 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIG-LLKISWEKPVF 563
++ +W+ ++LG + S P VKP PP ++ + + +LK++W P
Sbjct: 191 FVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
Query: 564 PENN-LQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--CAVYAVQVRCKRLDGLG 620
L++ I+Y W D S S V DL Y ++RC + DG G
Sbjct: 250 KSVIILKYNIQYRTKDAST-WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
Query: 621 YWSNWSNPA 629
YWS+WS A
Sbjct: 309 YWSDWSEEA 317
Score = 52.0 bits (123), Expect = 3e-06
Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 15/117 (12%)
Query: 214 KITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGN--LKISWSSPPL-----VPFP 266
K+TS + F P+ VKP+PP L + +++ + LK++W++P + + +
Sbjct: 206 KVTSDHINFD-------PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
Query: 267 LQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
+QY+ K + + + E D + +S V + P + Y ++R + DG G WSDWS
Sbjct: 259 IQYRTKDASTWSQIPPE-DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 60.8 bits (146), Expect = 7e-09
Identities = 88/409 (21%), Positives = 159/409 (38%), Gaps = 38/409 (9%)
Query: 412 CCNEHECHHRYAELYV---IDVNINISCETDGYLTKMTCRWSTSTIQSL-AESTLQLRYH 467
C N E AE++V + N+SC G + C W L E TLQL
Sbjct: 105 CINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGP 164
Query: 468 RSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPT 527
++ + I+ C G P S +T + +SLGS S P+
Sbjct: 165 KNLTWQKQCKDIY-------CDYLDFGIN---LTPESPESNFTAKVTAVNSLGSSSSLPS 214
Query: 528 CVLPDSVVKPLPPSSVKAEI-TINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMY 586
+V+PLPP ++ + ++ + W N ++RY S + W M
Sbjct: 215 TFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLN---RLRYRPSNSRL-WNMV 270
Query: 587 EVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFW 646
V AK + L + Y Q+ K G WS+WS + + P + W
Sbjct: 271 NVTKAKGRHDLLDLKPF-TEYEFQISSKLHLYKGSWSDWSESLRAQTPE-EEPTGMLDVW 328
Query: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNG-TWSEDVGNHTKFTFLW 705
+ +++ ++L WK L +++ + Y + G ++++ HT +T +
Sbjct: 329 YMKRHIDYSRQQ-ISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVI 387
Query: 706 TEQAH-TVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSD 764
+ V V A NS G+S+ + + + + +SA ++V+W D
Sbjct: 388 PRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD 447
Query: 765 -YKLMYFIIEWKNLNEDGE----IKWLR---------ISSSVKKYYIHD 799
+ +++EW+ L+ G+ + WLR IS ++K Y ++
Sbjct: 448 PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYE 496
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 58.2 bits (139), Expect = 5e-08
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 233 NMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFP----LQYQVKYSENSTTVIREADKIV 288
+++KPDPP G+ + + L++ W P PFP L+Y ++Y I
Sbjct: 125 HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPI- 183
Query: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFT 329
ATS ++ ++ P + Y VQV + L G SDWS P T
Sbjct: 184 EATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATAT 224
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 503 IFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKP- 561
+F ++ Y + + H GS S + + ++KP PP V+ + L++ WE P
Sbjct: 96 LFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRLS-PLAERQLQVQWEPPG 153
Query: 562 --VFPEN-NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDG 618
FPE +L++ IRY G + + V ++ S L A Y VQV + L
Sbjct: 154 SWPFPEIFSLKYWIRYKRQGAA---RFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
Query: 619 LGYWSNWSNPA 629
G S+WS PA
Sbjct: 211 YGELSDWSLPA 221
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 55.8 bits (133), Expect = 2e-07
Identities = 72/304 (23%), Positives = 121/304 (39%), Gaps = 41/304 (13%)
Query: 344 VGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRG 403
+GS++ C + ++ + W +N ++P V++ + NLN ++ R
Sbjct: 52 IGSSLLATCSVHGDPPGATAEGLYWTLN-GRRLPPELSRVLNASTLALALANLNGSRQRS 110
Query: 404 KFTYDAVYCCNEHECHHRYAELYV---IDVNINISCETDGYLTKMTCRWSTST-----IQ 455
D + C + LYV + +NISC + + +TCRW+ +
Sbjct: 111 G---DNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKN-MKDLTCRWTPGAHGETFLH 166
Query: 456 SLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRI 515
+ +LR++ C + ++ P S C++ D + L + Y +W+
Sbjct: 167 TNYSLKYKLRWYGQDNTCEEYHTVGPHS----CHIPKD---------LALFTPYEIWVEA 213
Query: 516 NHSLGSLDSPP-TCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNL---QFQ 571
+ LGS S T + D V PP + + L + W P ++ L ++Q
Sbjct: 214 TNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQ 273
Query: 572 IRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLC--AVYAVQVRCKRLD-----GLGYWSN 624
IRY + V WK V D S S + L VY VQVRC G WS
Sbjct: 274 IRYRVEDS-VDWK---VVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSE 329
Query: 625 WSNP 628
WS+P
Sbjct: 330 WSHP 333
Score = 55.1 bits (131), Expect = 4e-07
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
Query: 223 QSPLMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVP---FPLQYQVKYSENS 277
+S ++++ +++V DPP +H+ + L + W SPP + F +YQ++Y
Sbjct: 221 RSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVED 280
Query: 278 TTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRL-----DGPGIWSDWSTPRVFTT 330
+ + D + + TS + + PG+ Y VQVR GIWS+WS P +T
Sbjct: 281 SVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAAST 338
>gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo
sapiens]
Length = 2299
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/124 (28%), Positives = 62/124 (50%), Gaps = 7/124 (5%)
Query: 213 LKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFP-LQYQV 271
+ I+S + SP+ + N+ KP PP+ L E + +SW++PP + Y V
Sbjct: 32 ITISSISTTYTSPVTRIVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIV 91
Query: 272 KYSEN---STTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVF 328
KY E TV + + +L+ ++ PG++YE++V + G G++SD P +F
Sbjct: 92 KYKEVCPWMQTVYTQVRSKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSD---PFLF 148
Query: 329 TTQD 332
T +
Sbjct: 149 QTAE 152
Score = 35.8 bits (81), Expect = 0.24
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 524 SPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQW 583
SP T ++ +V KP PP + E + G+L +SW P P + I Y + KEV
Sbjct: 43 SPVTRIVTTNVTKPGPPVFLAGERVGSAGIL-LSWNTPPNPNGRI---ISYIVKYKEVCP 98
Query: 584 KMYEVY-DAKSKSVSLPV----PDLCAVYAVQVRCKRLDGLGYWSN 624
M VY +SK SL V + Y ++V + G+G +S+
Sbjct: 99 WMQTVYTQVRSKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSD 144
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 51.2 bits (121), Expect = 6e-06
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287
+KP PP ++ +T G ISW S P LQY+++Y + + K+
Sbjct: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
Query: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331
+S S V S+LP SSYE+QVR + G G WS+WS P +F TQ
Sbjct: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
Score = 40.8 bits (94), Expect = 0.008
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)
Query: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Y C ++ + I G+ L +KP PP +V + G
Sbjct: 79 YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
Query: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604
ISW E P F + LQ++++Y G W + ++ S+SVSL +
Sbjct: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
Query: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646
+ Y +QVR + G Y WS WS+P + +++ + V + P FW
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696
+ K + LWK + ++ S +R+ + + C+G + + VG
Sbjct: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 51.2 bits (121), Expect = 6e-06
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287
+KP PP ++ +T G ISW S P LQY+++Y + + K+
Sbjct: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
Query: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331
+S S V S+LP SSYE+QVR + G G WS+WS P +F TQ
Sbjct: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
Score = 40.8 bits (94), Expect = 0.008
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)
Query: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Y C ++ + I G+ L +KP PP +V + G
Sbjct: 79 YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
Query: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604
ISW E P F + LQ++++Y G W + ++ S+SVSL +
Sbjct: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
Query: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646
+ Y +QVR + G Y WS WS+P + +++ + V + P FW
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696
+ K + LWK + ++ S +R+ + + C+G + + VG
Sbjct: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 51.2 bits (121), Expect = 6e-06
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287
+KP PP ++ +T G ISW S P LQY+++Y + + K+
Sbjct: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
Query: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331
+S S V S+LP SSYE+QVR + G G WS+WS P +F TQ
Sbjct: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
Score = 40.8 bits (94), Expect = 0.008
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)
Query: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Y C ++ + I G+ L +KP PP +V + G
Sbjct: 79 YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
Query: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604
ISW E P F + LQ++++Y G W + ++ S+SVSL +
Sbjct: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
Query: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646
+ Y +QVR + G Y WS WS+P + +++ + V + P FW
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696
+ K + LWK + ++ S +R+ + + C+G + + VG
Sbjct: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 45.1 bits (105), Expect = 4e-04
Identities = 48/179 (26%), Positives = 73/179 (40%), Gaps = 27/179 (15%)
Query: 190 VHECCECLVPVPTA--------KLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPL 241
+HEC + + P + + T +M + T+ S + V +V+PDPPL
Sbjct: 72 MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPL 131
Query: 242 GLHMEITDDGNLK----ISWSSPPLVP-----FPLQYQVKYSENSTTVIREADKIVSATS 292
L +E+ + K I WS P L+ F L Y+++ E T
Sbjct: 132 ELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAE-WEIHFAGQQTE 190
Query: 293 LLVDSILPGSSYEVQVRGKRLDGPGIWSDWS------TPRVFTTQD-VIYFPPKILTSV 344
+ S+ PG Y VQVR K G WS WS P FT D ++ +L++V
Sbjct: 191 FKILSLHPGQKYLVQVRCK--PDHGYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAV 247
Score = 40.0 bits (92), Expect = 0.013
Identities = 48/221 (21%), Positives = 79/221 (35%), Gaps = 47/221 (21%)
Query: 446 TCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFL 505
TC W T L + L YHR + P C+ Y +++
Sbjct: 45 TCWWRPGTDGGLP-TNYSLTYHREGETLMHECPDYITGGPNSCHFGKQ--YTSMWRT--- 98
Query: 506 LSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAE------------------- 546
Y M + + +GS S V +V+P PP + E
Sbjct: 99 ---YIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPT 155
Query: 547 -ITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCA 605
I + G + +E + PE +++I + +G++ ++K+ ++ +
Sbjct: 156 LIDLKTGWFTLLYEIRLKPEKAAEWEIHF--AGQQTEFKILSLHPGQK------------ 201
Query: 606 VYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFW 646
Y VQVRCK GYWS WS PA + + M W
Sbjct: 202 -YLVQVRCK--PDHGYWSAWS-PATFIQIPSDFTMNDTTVW 238
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 43.5 bits (101), Expect = 0.001
Identities = 45/216 (20%), Positives = 80/216 (37%), Gaps = 4/216 (1%)
Query: 434 ISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSD 493
+SC+ Y +C WS S I L L Y + ++ +D P + P C
Sbjct: 118 VSCQAADY-ENFSCTWSPSQISGLPTRYLT-SYRKKTVLGADSQRRSPSTGPWPCPQDPL 175
Query: 494 GFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGL 553
G C+ S Y + + + LG+ + V S+++P PP ++ E
Sbjct: 176 GAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVPGYPR 234
Query: 554 -LKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVR 612
L+ SW P F +++ L + Q + + + +AV+V
Sbjct: 235 RLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVS 294
Query: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRI 648
+ G WS WS A+ +P P + ++
Sbjct: 295 ARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
Score = 38.5 bits (88), Expect = 0.038
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 226 LMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVPFPLQYQVKYSENSTTVIRE 283
L+ V ++++PDPP GL +E L+ SW+ P P + +K+
Sbjct: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHP 266
Query: 284 ADKIVSATSL--LVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKI 340
A V L ++ + G + V+V + G WS WS P + T P +I
Sbjct: 267 AWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWS-PEAWGTPSTGTIPKEI 324
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 43.5 bits (101), Expect = 0.001
Identities = 45/216 (20%), Positives = 80/216 (37%), Gaps = 4/216 (1%)
Query: 434 ISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSD 493
+SC+ Y +C WS S I L L Y + ++ +D P + P C
Sbjct: 118 VSCQAADY-ENFSCTWSPSQISGLPTRYLT-SYRKKTVLGADSQRRSPSTGPWPCPQDPL 175
Query: 494 GFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGL 553
G C+ S Y + + + LG+ + V S+++P PP ++ E
Sbjct: 176 GAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVPGYPR 234
Query: 554 -LKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVR 612
L+ SW P F +++ L + Q + + + +AV+V
Sbjct: 235 RLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVS 294
Query: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRI 648
+ G WS WS A+ +P P + ++
Sbjct: 295 ARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
Score = 38.5 bits (88), Expect = 0.038
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 226 LMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVPFPLQYQVKYSENSTTVIRE 283
L+ V ++++PDPP GL +E L+ SW+ P P + +K+
Sbjct: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHP 266
Query: 284 ADKIVSATSL--LVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKI 340
A V L ++ + G + V+V + G WS WS P + T P +I
Sbjct: 267 AWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWS-PEAWGTPSTGTIPKEI 324
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 43.5 bits (101), Expect = 0.001
Identities = 45/216 (20%), Positives = 80/216 (37%), Gaps = 4/216 (1%)
Query: 434 ISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSD 493
+SC+ Y +C WS S I L L Y + ++ +D P + P C
Sbjct: 118 VSCQAADY-ENFSCTWSPSQISGLPTRYLT-SYRKKTVLGADSQRRSPSTGPWPCPQDPL 175
Query: 494 GFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGL 553
G C+ S Y + + + LG+ + V S+++P PP ++ E
Sbjct: 176 GAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVPGYPR 234
Query: 554 -LKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVR 612
L+ SW P F +++ L + Q + + + +AV+V
Sbjct: 235 RLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVS 294
Query: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRI 648
+ G WS WS A+ +P P + ++
Sbjct: 295 ARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
Score = 38.5 bits (88), Expect = 0.038
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 226 LMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVPFPLQYQVKYSENSTTVIRE 283
L+ V ++++PDPP GL +E L+ SW+ P P + +K+
Sbjct: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHP 266
Query: 284 ADKIVSATSL--LVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKI 340
A V L ++ + G + V+V + G WS WS P + T P +I
Sbjct: 267 AWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWS-PEAWGTPSTGTIPKEI 324
>gi|4885491 myeloproliferative leukemia virus oncogene precursor
[Homo sapiens]
Length = 635
Score = 41.2 bits (95), Expect = 0.006
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 28/142 (19%)
Query: 445 MTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGF------YEC 498
+TC W ++ T QL Y +P +P+ C L S Y C
Sbjct: 48 LTCFWDEE--EAAPSGTYQLLY------------AYPREKPRACPLSSQSMPHFGTRYVC 93
Query: 499 IF---QPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
F + + L +W++ N L + + DSV P PPS +KA G L+
Sbjct: 94 QFPDQEEVRLFFPLHLWVK-NVFLNQTRTQRVLFV-DSVGLPAPPSIIKAMGGSQPGELQ 151
Query: 556 ISWEKPVFPE--NNLQFQIRYG 575
ISWE+P PE + L++++RYG
Sbjct: 152 ISWEEPA-PEISDFLRYELRYG 172
Score = 36.6 bits (83), Expect = 0.14
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 206 NDTLLMCL-KITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSP-PLV 263
ND+++ L ++T+ S L S I+ P LH G+L++ W P
Sbjct: 358 NDSIIHILVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREISSGHLELEWQHPSSWA 417
Query: 264 PFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGP---GIWS 320
YQ++Y+ + + + A ++ + P S Y +Q+R RL+GP G WS
Sbjct: 418 AQETCYQLRYTGEGHQDWKVLEPPLGARGGTLE-LRPRSRYRLQLRA-RLNGPTYQGPWS 475
Query: 321 DWSTP-RVFTTQDVIY 335
WS P RV T + +
Sbjct: 476 SWSDPTRVETATETAW 491
>gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
sapiens]
Length = 380
Score = 41.2 bits (95), Expect = 0.006
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 10/144 (6%)
Query: 196 CLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKI 255
C P A +C+ +S +S + Q N+VKP PP+ L +K+
Sbjct: 197 CRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKL 256
Query: 256 SWSSPPLVPFP---LQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGK- 311
WS PL P P Y+++ E+ TT++ V + + + VR K
Sbjct: 257 KWSI-PLGPIPARCFDYEIEIREDDTTLVTAT---VENETYTLKTTNETRQLCFVVRSKV 312
Query: 312 --RLDGPGIWSDWSTPRVFTTQDV 333
GIWS+WS + + +D+
Sbjct: 313 NIYCSDDGIWSEWSDKQCWEGEDL 336
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 40.8 bits (94), Expect = 0.008
Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 12/200 (6%)
Query: 434 ISCETDGYLTKMTCRWSTSTIQSLA-ESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQS 492
+SC L+ + C W + SL ++ L +R ++S EP +S
Sbjct: 119 LSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNS-------PAEDFQEPCQYSQES 171
Query: 493 DGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAE-ITINI 551
F + P S Y + + + S+GS S +++P PP+++ + N
Sbjct: 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
Query: 552 GLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAV--YAV 609
L ++W+ P N+ +++R+ L + + K + + K + D + + V
Sbjct: 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
Query: 610 QVRCKRLDGLGYWSNWSNPA 629
Q+R + G G WS WS A
Sbjct: 291 QLRAQEEFGQGEWSEWSPEA 310
Score = 35.4 bits (80), Expect = 0.32
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 16/153 (10%)
Query: 196 CLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGN--L 253
C + VP + ++ +S G F S + Q +++PDPP + + L
Sbjct: 176 CQLAVPEGDSSFYIVSMCVASSVGSKF-SKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
Query: 254 KISWSSPPL-------VPFPLQYQVKYSENSTT-VIREADKIVSATSLLVDSILPGSSYE 305
++W P + F L+Y+ + S+ TT ++++ ++ G +
Sbjct: 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQH-----HCVIHDAWSGLRHV 289
Query: 306 VQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPP 338
VQ+R + G G WS+WS + T PP
Sbjct: 290 VQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 40.8 bits (94), Expect = 0.008
Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 12/200 (6%)
Query: 434 ISCETDGYLTKMTCRWSTSTIQSLA-ESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQS 492
+SC L+ + C W + SL ++ L +R ++S EP +S
Sbjct: 119 LSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNS-------PAEDFQEPCQYSQES 171
Query: 493 DGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAE-ITINI 551
F + P S Y + + + S+GS S +++P PP+++ + N
Sbjct: 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
Query: 552 GLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAV--YAV 609
L ++W+ P N+ +++R+ L + + K + + K + D + + V
Sbjct: 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
Query: 610 QVRCKRLDGLGYWSNWSNPA 629
Q+R + G G WS WS A
Sbjct: 291 QLRAQEEFGQGEWSEWSPEA 310
Score = 35.4 bits (80), Expect = 0.32
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 16/153 (10%)
Query: 196 CLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGN--L 253
C + VP + ++ +S G F S + Q +++PDPP + + L
Sbjct: 176 CQLAVPEGDSSFYIVSMCVASSVGSKF-SKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
Query: 254 KISWSSPPL-------VPFPLQYQVKYSENSTT-VIREADKIVSATSLLVDSILPGSSYE 305
++W P + F L+Y+ + S+ TT ++++ ++ G +
Sbjct: 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQH-----HCVIHDAWSGLRHV 289
Query: 306 VQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPP 338
VQ+R + G G WS+WS + T PP
Sbjct: 290 VQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
>gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
Length = 629
Score = 40.0 bits (92), Expect = 0.013
Identities = 65/307 (21%), Positives = 121/307 (39%), Gaps = 44/307 (14%)
Query: 334 IYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393
I+ P + +G N+S +C +N P K + + E+ Q ++ +++ +
Sbjct: 34 IWVEPATIFKMGMNISIYCQAAIKN-CQPRKLHFYKNGIKERF---QITRINKTTARLWY 89
Query: 394 FNLNETKPRGKFTYDAVYC---CNEHE-----CHHRYAELYVIDVNINISCETDGYLTKM 445
N E + ++YC C +H C + Y D+ ++C Y M
Sbjct: 90 KNFLEP-------HASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNM 142
Query: 446 TCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFL 505
TC W+ + + + Y + S+ +E + YL S + +
Sbjct: 143 TCTWNAGKLTYI-----------DTKYVVHVKSLE--TEEEQQYLTS-SYINISTDSLQG 188
Query: 506 LSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK--ISWEKPVF 563
Y +W++ ++LG +S + D +V P +AE TIN + K I W+
Sbjct: 189 GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAE-TINATVPKTIIYWDSQTT 247
Query: 564 PENNLQFQIRYGLSGKEVQWKMYEV---YDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLG 620
E + ++RY + + W + E + +S P++ Y QVRC+ G
Sbjct: 248 IE-KVSCEMRYKATTNQT-WNVKEFDTNFTYVQQSEFYLEPNI--KYVFQVRCQE-TGKR 302
Query: 621 YWSNWSN 627
YW WS+
Sbjct: 303 YWQPWSS 309
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 40.0 bits (92), Expect = 0.013
Identities = 35/155 (22%), Positives = 68/155 (43%), Gaps = 22/155 (14%)
Query: 189 SVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEIT 248
S+H C +PVP + ++ ++ + + S I M P + +T
Sbjct: 299 SLHTRHHCQIPVPDPATHGQYIVSVQPRRA----EKHIKSSVNIQMAPPS------LNVT 348
Query: 249 DDGN-LKISWSSPPLV------PFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPG 301
DG+ + W + + F +QY+ + +T + + + +A S+ + ++ P
Sbjct: 349 KDGDSYSLRWETMKMRYEHIDHTFEIQYR---KDTATWKDSKTETLQNAHSMALPALEPS 405
Query: 302 SSY--EVQVRGKRLDGPGIWSDWSTPRVFTTQDVI 334
+ Y V+VR R GIWS+WS R + T+ V+
Sbjct: 406 TRYWARVRVRTSRTGYNGIWSEWSEARSWDTESVL 440
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,797,932
Number of Sequences: 37866
Number of extensions: 2247507
Number of successful extensions: 5304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 4928
Number of HSP's gapped (non-prelim): 397
length of query: 1165
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1052
effective length of database: 13,968,660
effective search space: 14695030320
effective search space used: 14695030320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.