Search of human proteins with 39777597

Search of human proteins with 39777597

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
         (687 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39777597 transglutaminase 2 isoform a [Homo sapiens]              1410   0.0  
gi|39777599 transglutaminase 2 isoform b [Homo sapiens]              1122   0.0  
gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]               541   e-154
gi|16445035 transglutaminase 7 [Homo sapiens]                         529   e-150
gi|148664232 transglutaminase 6 [Homo sapiens]                        499   e-141
gi|189458821 transglutaminase 3 precursor [Homo sapiens]              487   e-137
gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]                447   e-125
gi|4507475 transglutaminase 1 [Homo sapiens]                          433   e-121
gi|119395709 coagulation factor XIII A1 subunit precursor [Homo ...   417   e-116
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho...   374   e-103
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho...   372   e-103
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]             360   2e-99
gi|24475847 influenza virus NS1A binding protein [Homo sapiens]        31   3.3  
gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens]     31   4.4  
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ...    30   5.7  
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ...    30   5.7  
gi|68160947 secretogranin II precursor [Homo sapiens]                  30   5.7  

>gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
          Length = 687

 Score = 1410 bits (3651), Expect = 0.0
 Identities = 687/687 (100%), Positives = 687/687 (100%)

Query: 1   MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 60
           MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS
Sbjct: 1   MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 60

Query: 61  VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120
           VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE
Sbjct: 61  VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120

Query: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180
           ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW
Sbjct: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180

Query: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240
           NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR
Sbjct: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240

Query: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300
           WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN
Sbjct: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300

Query: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360
           YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT
Sbjct: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360

Query: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 420
           PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL
Sbjct: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 420

Query: 421 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 480
           IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG
Sbjct: 421 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 480

Query: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 540
           QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK
Sbjct: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 540

Query: 541 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 600
           SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK
Sbjct: 541 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 600

Query: 601 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 660
           RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG
Sbjct: 601 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 660

Query: 661 LHKLVVNFESDKLKAVKGFRNVIIGPA 687
           LHKLVVNFESDKLKAVKGFRNVIIGPA
Sbjct: 661 LHKLVVNFESDKLKAVKGFRNVIIGPA 687


>gi|39777599 transglutaminase 2 isoform b [Homo sapiens]
          Length = 548

 Score = 1122 bits (2903), Expect = 0.0
 Identities = 539/542 (99%), Positives = 541/542 (99%)

Query: 1   MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 60
           MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS
Sbjct: 1   MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 60

Query: 61  VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120
           VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE
Sbjct: 61  VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120

Query: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180
           ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW
Sbjct: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180

Query: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240
           NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR
Sbjct: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240

Query: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300
           WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN
Sbjct: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300

Query: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360
           YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT
Sbjct: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360

Query: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 420
           PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL
Sbjct: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 420

Query: 421 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 480
           IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG
Sbjct: 421 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 480

Query: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 540
           QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFS K
Sbjct: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSGK 540

Query: 541 SV 542
           ++
Sbjct: 541 AL 542


>gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]
          Length = 720

 Score =  541 bits (1395), Expect = e-154
 Identities = 296/721 (41%), Positives = 405/721 (56%), Gaps = 42/721 (5%)

Query: 1   MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 60
           MA+ L +   DL+   N   HHT ++  + L+VRRGQ F LTL+F  R+++  +D++ F 
Sbjct: 1   MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFV 60

Query: 61  VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120
           V TGP P    GT+A F L        W A +      +  + L  P  A +G Y L + 
Sbjct: 61  VETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIH 120

Query: 121 ASTGYQGS--SFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNI 178
             + +QGS  ++ LG FILLFN WCP DAVYLDSE +RQEYV+   GFIYQGS  +I+  
Sbjct: 121 IDS-FQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPC 179

Query: 179 PWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLL 238
           PWN+GQFED I+DICL LLD +  F  +   DC+ R SPVYV RVV  M+N NDD GVL 
Sbjct: 180 PWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLN 239

Query: 239 GRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVV 298
           G W  NY DG +P  W GSV IL++W   GCQ V+YGQCWVFAAV CTV+RCLGIPTRV+
Sbjct: 240 GNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVI 299

Query: 299 TNYNSAHDQNSNLLIEYFRNEFGEIQGD-KSEMIWNFHCWVESWMTRPDLQPGYEGWQAL 357
           TN++S HD + NL+I+ + +  G I G+ K + IWNFH W E WM R DL P Y GWQ L
Sbjct: 300 TNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVL 359

Query: 358 DPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSIN 417
           D TPQE S G YCCGP  VRAIKEG++   YD PFVF+ VNAD + W+ Q  G   K   
Sbjct: 360 DATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQ-GGKEQKLHQ 418

Query: 418 RSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAF--------------------- 456
            +  VG  ISTKS+  DER+DIT  YKY EGS +ER+ F                     
Sbjct: 419 DTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAEL 478

Query: 457 ------------TRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYV 504
                        R+ H   L   +   ++++ ++    NMG D        N +++   
Sbjct: 479 QPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKD 538

Query: 505 CRLLLCARTVSYNGI-LGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKV 563
            ++ L A+++ ++G  L P       + L+  P   K+ P  I Y +Y   L+   LI++
Sbjct: 539 LKVNLSAQSLLHDGSPLSPFWQDTAFITLS--PKEAKTYPCKISYSQYSQYLSTDKLIRI 596

Query: 564 RALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFT 623
            AL  E      +L  + + L  P I I +LG     + L  +V   NPL   +E C  T
Sbjct: 597 SALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLT 656

Query: 624 VEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVI 683
           VEG+GL ++Q+ V +   ++   +  + ++ +P   G  ++  N  S+K K +KG+RNV 
Sbjct: 657 VEGSGLFKKQQKVFL-GVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVY 715

Query: 684 I 684
           +
Sbjct: 716 V 716


>gi|16445035 transglutaminase 7 [Homo sapiens]
          Length = 710

 Score =  529 bits (1362), Expect = e-150
 Identities = 294/707 (41%), Positives = 413/707 (58%), Gaps = 36/707 (5%)

Query: 5   LVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTG 64
           L LE  DL+   N ++HHT ++  ++L VRRGQPF+L L F  R +++  D +TF   TG
Sbjct: 7   LRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFS-RPFQSQNDHITFVAETG 65

Query: 65  PAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTG 124
           P PS+  GT+A F L        W+A+       +L + L TPANA IG Y L +E S G
Sbjct: 66  PKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKIEISQG 125

Query: 125 YQGSS--FVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNF 182
            QG S  + LG FILLFN W P D VYL SE   QEY++   GF+Y+G  +FI + PWN+
Sbjct: 126 -QGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSWPWNY 184

Query: 183 GQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWD 242
           GQFE+ I+DIC  +L+ +   LKN  +DCS+R+  VYV RVVS M+N NDD GVL G W 
Sbjct: 185 GQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQGNWG 244

Query: 243 NNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYN 302
            +Y  GVSP+ W GSV IL++W   G Q VKYGQCWVFA+V CTV+RCLG+PTRVV+N+ 
Sbjct: 245 EDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVVSNFR 304

Query: 303 SAHDQNSNLLIE-YFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTP 361
           SAH+ + NL I+ Y+      +   K + IWNFH W E WM R DL PGY GWQ LDPTP
Sbjct: 305 SAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVLDPTP 364

Query: 362 QEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLI 421
           Q+ S G +CCGP  V+AI+EGD+   YD PFV+AEVNAD V W+  D  +     + +  
Sbjct: 365 QQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAHNTSS 424

Query: 422 VGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANH---------LNKLAEKEETG 472
           +G +ISTK VG D+R+ IT +YKYPEGS EER  F +A+          L  L   E  G
Sbjct: 425 IGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLLESGG 484

Query: 473 M-----AMRIRVGQSMNMGSDFDVFAHI---TNNTAEEYVCRLLL--CARTVSYNGILGP 522
           +      +++ + +    G D  +   I    ++T       L++  CA+ + + G    
Sbjct: 485 LRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHGG---- 540

Query: 523 ECGT-----KYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLL 577
             GT     ++ + +NL+   E   PL + Y  YR+ LT+  LI+V  +         +L
Sbjct: 541 --GTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRSML 598

Query: 578 AERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVE 637
             +D+ LE P + I +    +  + L   V+L N L VAL  CT  +EG+GL   Q   +
Sbjct: 599 VLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKD 658

Query: 638 IPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
           +   V AG  +++++DL P   G  +L V   S+++K +KG++++ +
Sbjct: 659 LGTLV-AGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFV 704


>gi|148664232 transglutaminase 6 [Homo sapiens]
          Length = 706

 Score =  499 bits (1286), Expect = e-141
 Identities = 289/706 (40%), Positives = 402/706 (56%), Gaps = 35/706 (4%)

Query: 9   RCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPS 68
           + D +   NG  HHT +    +LVVRRGQ F LTL    R  +   + L F++ TGP  S
Sbjct: 8   KVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELS-RALDCE-EILIFTMETGPRAS 65

Query: 69  QEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGS 128
           +   TKA F   +      WTA    Q + TL++ L +P +A IG Y LS+  S+  + S
Sbjct: 66  EALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHRKHS 125

Query: 129 SFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDG 188
           +  LG F+LLFN WC  D V+L SEEERQEYVL+  G I++G  K I+   WN+GQFE+ 
Sbjct: 126 NRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEED 185

Query: 189 ILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDG 248
           IL+ICL +LD +P    N   D S R +P+YV RV+S MVN N+D+GV+ G+W   YG G
Sbjct: 186 ILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYGGG 245

Query: 249 VSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQN 308
            SP+ W GSV IL++W     + VKYGQCWVFA V CTVLRCLGI TRVV+N+NSAHD +
Sbjct: 246 TSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHDTD 305

Query: 309 SNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEG 367
            NL ++ + + FG    D +E  +WNFH W ESW  R DL P Y GWQ LD TPQE+SEG
Sbjct: 306 QNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQEESEG 365

Query: 368 TYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKIS 427
            + CGP  V AI+EGD+   +D PFVFAEVNAD + W+  +D S  +  + +  +G  IS
Sbjct: 366 VFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIGRCIS 425

Query: 428 TKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETG--------------- 472
           TK+VG D R DIT  YKYPEGS +ER+ +++A  +N+L   E +G               
Sbjct: 426 TKAVGSDSRVDITDLYKYPEGSRKERQVYSKA--VNRLFGVEASGRRIWIRRAGGRCLWR 483

Query: 473 -----------MAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILG 521
                      +A + +V +   +G D  +   + N T+     R+ L   T+ Y     
Sbjct: 484 DDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTRKPV 543

Query: 522 PECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERD 581
            E   +    + L P  EK +P+ I Y KY++ LTE   I + A+ +       LL E+D
Sbjct: 544 AEILHESHA-VRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTK-GEKLLVEKD 601

Query: 582 LYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDP 641
           + LE+  I I++LG       +  EV++ NPL   ++ C   VEG+GL +EQ ++++P  
Sbjct: 602 ITLED-FITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVP-T 659

Query: 642 VEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA 687
           +E  E   V+ D+ P   G  +L V+  S     +KGF  V +  A
Sbjct: 660 LEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATA 705


>gi|189458821 transglutaminase 3 precursor [Homo sapiens]
          Length = 693

 Score =  487 bits (1254), Expect = e-137
 Identities = 264/682 (38%), Positives = 387/682 (56%), Gaps = 24/682 (3%)

Query: 17  NGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKAR 76
           N + HHT     ++L++RRGQ F + +         S + L F V TGP PS+ A TKA 
Sbjct: 16  NRQAHHTDKFSSQELILRRGQNFQVLMIMN--KGLGSNERLEFIVSTGPYPSESAMTKAV 73

Query: 77  FPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFI 136
           FPL +    G W+A +      TL++ +++PA+APIG Y ++L+  +    SS  LG FI
Sbjct: 74  FPLSNG-SSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGISSVKLGTFI 132

Query: 137 LLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLIL 196
           LLFN W   D+V++ +  ER+EYV    G I+ GS   I  I WNFGQFE+ IL ICL +
Sbjct: 133 LLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFEEDILSICLSI 192

Query: 197 LDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIG 256
           LD +  F ++A  D + R+ P YVGRV+S M+N NDD GVL G W   Y  G  P SW G
Sbjct: 193 LDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYTGGRDPRSWNG 252

Query: 257 SVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYF 316
           SV+IL+ WK  G   V+YGQCWVFA    T LR LGIP+RV+TN+NSAHD + NL ++ +
Sbjct: 253 SVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHDTDRNLSVDVY 312

Query: 317 RNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPV 376
            +  G      S+ +WNFH W E W  R DL P Y GWQ LD TPQE+S+G + CGP  V
Sbjct: 313 YDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERSQGVFQCGPASV 372

Query: 377 RAIKEGDLSTKYDAPFVFAEVNADVVDWIQQD-DGSVHKSINRSLIVGLKISTKSVGRDE 435
             ++EGD+   +D PF+FAEVNAD + W+  +  G   K+   S  +G  ISTK+VG + 
Sbjct: 373 IGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGRYISTKAVGSNA 432

Query: 436 REDITHTYKYPEGSSEEREAFTRANHLNKL---------------AEKEETGMAMRIRVG 480
           R D+T  YKYPEGS +ER+ F +A  L KL                E++E  +  +++V 
Sbjct: 433 RMDVTDKYKYPEGSDQERQVFQKA--LGKLKPNTPFAATSSMGLETEEQEPSIIGKLKVA 490

Query: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 540
             + +G + ++   + N + +     + + A T+ YNG L  E   K    ++L+P  E 
Sbjct: 491 GMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEV-WKDSATMSLDPEEEA 549

Query: 541 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 600
             P+ I Y +Y   L   N+I++ A+   P   S ++ ERD+ L+NP + + +L E + +
Sbjct: 550 EHPIKISYAQYEKYLKSDNMIRITAVCKVP-DESEVVVERDIILDNPTLTLEVLNEARVR 608

Query: 601 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 660
           + +  ++   NPL   +  C   VEG+GL      +++P  +   E  +VR D+LP   G
Sbjct: 609 KPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVP-TLGPKEGSRVRFDILPSRSG 667

Query: 661 LHKLVVNFESDKLKAVKGFRNV 682
             +L+ +F  +K  A+K   ++
Sbjct: 668 TKQLLADFSCNKFPAIKAMLSI 689


>gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]
          Length = 638

 Score =  447 bits (1150), Expect = e-125
 Identities = 241/574 (41%), Positives = 326/574 (56%), Gaps = 39/574 (6%)

Query: 146 DAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLK 205
           DAVYLDSE +RQEYV+   GFIYQGS  +I+  PWN+GQFED I+DICL LLD +  F  
Sbjct: 65  DAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQT 124

Query: 206 NAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWK 265
           +   DC+ R SPVYV RVV  M+N NDD GVL G W  NY DG +P  W GSV IL++W 
Sbjct: 125 DPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWN 184

Query: 266 NHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQG 325
             GCQ V+YGQCWVFAAV CTV+RCLGIPTRV+TN++S HD + NL+I+ + +  G I G
Sbjct: 185 ATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILG 244

Query: 326 D-KSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDL 384
           + K + IWNFH W E WM R DL P Y GWQ LD TPQE S G YCCGP  VRAIKEG++
Sbjct: 245 NKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEV 304

Query: 385 STKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYK 444
              YD PFVF+ VNAD + W+ Q  G   K    +  VG  ISTKS+  DER+DIT  YK
Sbjct: 305 DLNYDTPFVFSMVNADCMSWLVQ-GGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYK 363

Query: 445 YPEGSSEEREAF---------------------------------TRANHLNKLAEKEET 471
           Y EGS +ER+ F                                  R+ H   L   +  
Sbjct: 364 YEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVV 423

Query: 472 GMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGI-LGPECGTKYLL 530
            ++++ ++    NMG D        N +++    ++ L A+++ ++G  L P       +
Sbjct: 424 QVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFI 483

Query: 531 NLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIK 590
            L+  P   K+ P  I Y +Y   L+   LI++ AL  E      +L  + + L  P I 
Sbjct: 484 TLS--PKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSIT 541

Query: 591 IRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKV 650
           I +LG     + L  +V   NPL   +E C  TVEG+GL ++Q+ V +   ++   +  +
Sbjct: 542 INVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFL-GVLKPQHQASI 600

Query: 651 RMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
            ++ +P   G  ++  N  S+K K +KG+RNV +
Sbjct: 601 ILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 634



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 26/66 (39%), Positives = 40/66 (60%)

Query: 1  MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 60
          MA+ L +   DL+   N   HHT ++  + L+VRRGQ F LTL+F  R+++  +D++ F 
Sbjct: 1  MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFV 60

Query: 61 VVTGPA 66
          V T  A
Sbjct: 61 VETEDA 66


>gi|4507475 transglutaminase 1 [Homo sapiens]
          Length = 817

 Score =  433 bits (1113), Expect = e-121
 Identities = 251/681 (36%), Positives = 361/681 (53%), Gaps = 22/681 (3%)

Query: 15  ETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTK 74
           + N R+HHT +   ++L+VRRGQPF + L    R YE+S D +T  ++ G  P    GT 
Sbjct: 123 DQNRREHHTDEYEYDELIVRRGQPFHMLLLLS-RTYESS-DRITLELLIGNNPEVGKGTH 180

Query: 75  ARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTG---YQGSSFV 131
              P+      G W A VV      L+L++ T  NA IG ++ ++   +    +Q     
Sbjct: 181 VIIPVGKG-GSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDP 239

Query: 132 LGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILD 191
                +LFN WCP D VY+D E+ RQEYVL + G IY G+   I    WN+GQF+ G+LD
Sbjct: 240 RNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLD 299

Query: 192 ICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSP 251
            CL +LD         G     R  PV V RV+S MVN  DD GVL+G W  +Y  G +P
Sbjct: 300 ACLYILD-------RRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNP 352

Query: 252 MSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNL 311
            +W+GSV+IL  +   G   V YGQCWVFA V  TVLRCLG+ TR VTN+NSAHD +++L
Sbjct: 353 SAWVGSVEILLSYLRTGYS-VPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSL 411

Query: 312 LIE-YFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYC 370
            ++ YF      ++    + +WNFH W + WM RPDL  G++GWQ +D TPQE S G +C
Sbjct: 412 TMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFC 471

Query: 371 CGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKS 430
           CGP  V +IK G +  KYD PF+FAEVN+D V W +QDDGS          +G  I TK+
Sbjct: 472 CGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKA 531

Query: 431 VGRDEREDITHTYKYPEGSSEEREAF-TRANHLNKLAEKEETGMAMRIRV---GQSMNMG 486
           +  + REDIT+ YK+PEGS  ER+A  T A H +K       G A  + +    Q   MG
Sbjct: 532 ISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMG 591

Query: 487 SDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVPLCI 546
            D  V   + N+++     +L L      Y G+ G     +    + L P +   V + +
Sbjct: 592 QDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSG-TIFKETKKEVELAPGASDRVTMPV 650

Query: 547 LYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAE 606
            Y++YR  L +   + +            L  +    L  P++ + +LG     ++   +
Sbjct: 651 AYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQ 710

Query: 607 VSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVV 666
           +  +NPLPV L    F +EG+GL +  K + + D +   E V +R   +P+  G  +L+ 
Sbjct: 711 IVFKNPLPVTLTNVVFRLEGSGL-QRPKILNVGD-IGGNETVTLRQSFVPVRPGPRQLIA 768

Query: 667 NFESDKLKAVKGFRNVIIGPA 687
           + +S +L  V G   V + PA
Sbjct: 769 SLDSPQLSQVHGVIQVDVAPA 789


>gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
           sapiens]
          Length = 732

 Score =  417 bits (1072), Expect = e-116
 Identities = 260/684 (38%), Positives = 355/684 (51%), Gaps = 30/684 (4%)

Query: 15  ETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTK 74
           +TN  DHHT      KL+VRRGQ F++ + F  R Y+   D      V G  P +  GT 
Sbjct: 59  DTNKVDHHTDKYENNKLIVRRGQSFYVQIDFS-RPYDPRRDLFRVEYVIGRYPQENKGTY 117

Query: 75  ARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGY---QGSSFV 131
              P+   ++ G W A +V ++D ++ L + +     +G +R+ +   T Y   + S   
Sbjct: 118 IPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNP 177

Query: 132 LGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILD 191
                +LFN WC  DAVYLD+E+ER+EYVL   G I+ G    IK   W++GQFEDGILD
Sbjct: 178 ETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILD 237

Query: 192 ICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSP 251
            CL ++D        A  D S R +P+ V RV S MVN  DD+GVL+G WDN Y  GV P
Sbjct: 238 TCLYVMD-------RAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPP 290

Query: 252 MSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNL 311
            +W GSVDIL  +++     V+YGQCWVFA V  T LRCLGIP R+VTNY SAHD ++NL
Sbjct: 291 SAWTGSVDILLEYRSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANL 349

Query: 312 LIEYFRNEFGEIQGDKS-EMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYC 370
            ++ F  E G +    + + +WN+HCW E+WMTRPDL  G+ GWQA+D TPQE S+G Y 
Sbjct: 350 QMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYR 409

Query: 371 CGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKS 430
           CGP  V+AIK G +  ++DAPFVFAEVN+D++    + DG+       +  +G  I TK 
Sbjct: 410 CGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQ 469

Query: 431 VGRDEREDITHTYKYPEGSSEEREAFTRA------NHLN-KLAEKEETGMAMRIRVGQSM 483
           +G D   DIT TYK+ EG  EER A   A        LN +   K  + + M   V  ++
Sbjct: 470 IGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAV 529

Query: 484 NMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVP 543
            +G DF +     NN+   Y     L A    Y G+   E   K   ++ LEP S K   
Sbjct: 530 -LGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEF-KKETFDVTLEPLSFKKEA 587

Query: 544 LCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKL 603
           + I   +Y   L E   +              L  ++   L  PEI I++ G       +
Sbjct: 588 VLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDM 647

Query: 604 VAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTV--EI-PDPVEAGEEVKVRMDLLPLHMG 660
              V   NPL   L      ++G G+T   K +  EI P+     EEV       P   G
Sbjct: 648 TVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEV-----CRPWVSG 702

Query: 661 LHKLVVNFESDKLKAVKGFRNVII 684
             KL+ +  SD L+ V G  +V I
Sbjct: 703 HRKLIASMSSDSLRHVYGELDVQI 726


>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
           sapiens]
          Length = 691

 Score =  374 bits (959), Expect = e-103
 Identities = 231/697 (33%), Positives = 353/697 (50%), Gaps = 26/697 (3%)

Query: 1   MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEG--RNYEASVDSLT 58
           M + L ++ CD +   N  +HHT  L   +L VRRGQPF + L+F    R +  ++  + 
Sbjct: 1   MGQALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVA 60

Query: 59  FSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLS 118
            +  TG  PS+   T+A FP+    +   W+A V ++   + ++ +TTPA+A IG Y L 
Sbjct: 61  LTAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLL 120

Query: 119 LEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNI 178
           L+ S   Q    +LG F LLFN W   DAV+L +E +R EY+L Q G IY G+A  I+  
Sbjct: 121 LQVSGRKQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAE 177

Query: 179 PWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLL 238
            W+FGQFE  ++D+ L LL  +        +   + S PV+V RV+  +++   +Q VL 
Sbjct: 178 SWDFGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLP 229

Query: 239 GRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVV 298
                   +G       GSV ILR+W     + V  GQ WV AAVACTVLRCLGIP RVV
Sbjct: 230 TPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVV 289

Query: 299 TNYNSAHDQNSNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQAL 357
           T + SA      LLI+ + NE G   G+     IW F    E WMTRP L  GY+GWQ L
Sbjct: 290 TTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQIL 349

Query: 358 DPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSIN 417
            P+          C  VPVRA+KEG L        +FA +NA  V W   +DG++  + +
Sbjct: 350 HPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDS 409

Query: 418 RSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEE------- 470
            +  VG  ISTK VG D  EDIT  YKYPEGS +E+E   R        EK+        
Sbjct: 410 NTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSL 469

Query: 471 ---TGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTK 527
              + + + ++   S+ +  D  +   + N++ +E   +L +  + V YNG+L  +   K
Sbjct: 470 ETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRK 529

Query: 528 YLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENP 587
             L+L L    EK + + + +  +     E+  +++ A+      N    A+ D+ +  P
Sbjct: 530 -KLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRP 588

Query: 588 EIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEE 647
            + I++  + +Q + L A VSLQN L   +E C  ++ G GL   +++      V     
Sbjct: 589 HLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRS-VWPENT 647

Query: 648 VKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
           +  +    P H+GL +L V  + +  + +  +++V +
Sbjct: 648 MCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 684


>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
           sapiens]
          Length = 721

 Score =  372 bits (954), Expect = e-103
 Identities = 230/695 (33%), Positives = 352/695 (50%), Gaps = 26/695 (3%)

Query: 3   EELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEG--RNYEASVDSLTFS 60
           + L ++ CD +   N  +HHT  L   +L VRRGQPF + L+F    R +  ++  +  +
Sbjct: 33  DALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALT 92

Query: 61  VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120
             TG  PS+   T+A FP+    +   W+A V ++   + ++ +TTPA+A IG Y L L+
Sbjct: 93  AQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQ 152

Query: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180
            S   Q    +LG F LLFN W   DAV+L +E +R EY+L Q G IY G+A  I+   W
Sbjct: 153 VSGRKQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESW 209

Query: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240
           +FGQFE  ++D+ L LL  +        +   + S PV+V RV+  +++   +Q VL   
Sbjct: 210 DFGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPTP 261

Query: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300
                 +G       GSV ILR+W     + V  GQ WV AAVACTVLRCLGIP RVVT 
Sbjct: 262 QTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTT 321

Query: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQALDP 359
           + SA      LLI+ + NE G   G+     IW F    E WMTRP L  GY+GWQ L P
Sbjct: 322 FASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHP 381

Query: 360 TPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRS 419
           +          C  VPVRA+KEG L        +FA +NA  V W   +DG++  + + +
Sbjct: 382 SAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNT 441

Query: 420 LIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEE--------- 470
             VG  ISTK VG D  EDIT  YKYPEGS +E+E   R        EK+          
Sbjct: 442 KYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLET 501

Query: 471 -TGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYL 529
            + + + ++   S+ +  D  +   + N++ +E   +L +  + V YNG+L  +   K  
Sbjct: 502 ASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRK-K 560

Query: 530 LNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEI 589
           L+L L    EK + + + +  +     E+  +++ A+      N    A+ D+ +  P +
Sbjct: 561 LHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHL 620

Query: 590 KIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVK 649
            I++  + +Q + L A VSLQN L   +E C  ++ G GL   +++      V     + 
Sbjct: 621 AIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRS-VWPENTMC 679

Query: 650 VRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
            +    P H+GL +L V  + +  + +  +++V +
Sbjct: 680 AKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714


>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
          Length = 684

 Score =  360 bits (925), Expect = 2e-99
 Identities = 236/709 (33%), Positives = 361/709 (50%), Gaps = 57/709 (8%)

Query: 2   AEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSV 61
           ++EL +   D   + N   HHT +      V RRGQ F L L             L FS 
Sbjct: 5   SKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFS- 63

Query: 62  VTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEA 121
            TGP PS    T      R   +  +W AT+ ++    +++ +T+  NA +G Y+L+++ 
Sbjct: 64  -TGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKT 122

Query: 122 STGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWN 181
                 S   +    LLFN WC  D V++  E+ER+EY+L   G  Y G+A+ IK  PWN
Sbjct: 123 GNHILKSEENI--LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWN 180

Query: 182 FGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRW 241
           FGQFE  +LD C+ LL         +    + R  PV V R +  M++    QGVL+G W
Sbjct: 181 FGQFEKNVLDCCISLLT-------ESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNW 233

Query: 242 DNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNY 301
             +Y  G +P  W GS  IL+++ N   Q V +GQCWVFA +  TVLR LGIP R VT +
Sbjct: 234 TGDYEGGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGF 292

Query: 302 NSAHDQNSNLLIEYFRNEFGE-IQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360
           +SAHD   NL ++ + NE GE I     + +WNFH W ++WM RPDL  GY+GWQA+D T
Sbjct: 293 DSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDAT 352

Query: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQ---DDGSVHKSIN 417
           PQE+S+G +CCGP P+ AI++GD+   YD  FVF+EVN D + W+ +       +H    
Sbjct: 353 PQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISM 412

Query: 418 RSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRI 477
            +  +G  ISTK+VG+D R DIT+ YKYPEGSSEER+    A  L  L+ + E    ++ 
Sbjct: 413 ETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLL--LSSEREHRRPVKE 470

Query: 478 RVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPF 537
                M++ SD  +  +  N T       ++L  +T +   +         L +  L+ +
Sbjct: 471 NF-LHMSVQSDDVLLGNSVNFT-------VILKRKTAALQNV-------NILGSFELQLY 515

Query: 538 S-EKSVPLCILYEKYR-------DCLTESNLIKVRALLV---EPVINSYLLAE----RDL 582
           + +K   LC L +  +         LT  +   + +L +   EPVI  +++AE    +++
Sbjct: 516 TGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEI 575

Query: 583 Y-------LENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKT 635
                    + PE  I +    +  + LV     +N L + L    F++E  G++  Q +
Sbjct: 576 MASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS 635

Query: 636 VEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
                 V+ GE ++ ++   P+  G  K +V   S ++K +   + V+I
Sbjct: 636 DH--GTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682


>gi|24475847 influenza virus NS1A binding protein [Homo sapiens]
          Length = 642

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 538 SEKSVPLCILYEKYRDCLTESNLI-KVRALLVEPVINSYLLAERDLYLENPEIKIRILGE 596
           S   V  CI Y  +  C+ +S L+ KV A + E ++    ++E + +L+ P +K+ ++ E
Sbjct: 127 SRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQ---ISEEEEFLKLPRLKLEVMLE 183


>gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
          Length = 985

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 4   ELVLERCDLELETNGRDHHTADLCREKLVVRRGQP-----FWLTLHFEGRNYEASV---- 54
           EL+LE   ++L++ G +    +  + +   R+ +P      WL +H  G      V    
Sbjct: 454 ELMLEEKGVQLDSAGLERLAQEEAQHR--ARQAEPVQKQGLWLDVHALGELQRQGVPPTD 511

Query: 55  DSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLT 105
           DS  ++    P+ S E GT     L+   E+G   A+V   Q C L L  T
Sbjct: 512 DSPKYNYSLRPSGSYEFGTCEAQVLQLYTEDGTAVASVGKGQRCGLLLDRT 562


>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
           [Homo sapiens]
          Length = 823

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)

Query: 561 IKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEV-SLQNPLPVALEG 619
           IK+   ++      Y     DL  EN  +   +L E + K+KL AE+ S Q+ L  A+  
Sbjct: 560 IKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISK 619

Query: 620 CTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDL 654
            +  V+    TE    + +    +  E+VK+  D+
Sbjct: 620 HSENVK----TERNLKLALERTQDISEQVKMSSDI 650


>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
           [Homo sapiens]
          Length = 823

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)

Query: 561 IKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEV-SLQNPLPVALEG 619
           IK+   ++      Y     DL  EN  +   +L E + K+KL AE+ S Q+ L  A+  
Sbjct: 560 IKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISK 619

Query: 620 CTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDL 654
            +  V+    TE    + +    +  E+VK+  D+
Sbjct: 620 HSENVK----TERNLKLALERTQDISEQVKMSSDI 650


>gi|68160947 secretogranin II precursor [Homo sapiens]
          Length = 617

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 14/52 (26%), Positives = 26/52 (50%)

Query: 43  LHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVD 94
           L  +    E+S D   +  V+ P   +E G ++  P RD++ E DW   +++
Sbjct: 65  LRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILE 116


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,058,271
Number of Sequences: 37866
Number of extensions: 1266439
Number of successful extensions: 2739
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2668
Number of HSP's gapped (non-prelim): 21
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.