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Search of human proteins with 39725957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39725957 DAZ interacting protein 1 isoform 2 [Homo sapiens]
(867 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39725957 DAZ interacting protein 1 isoform 2 [Homo sapiens] 1730 0.0
gi|7662436 DAZ interacting protein 1 isoform 1 [Homo sapiens] 1677 0.0
gi|27734911 DAZ interacting protein 1-like [Homo sapiens] 330 3e-90
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 60 7e-09
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 59 2e-08
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap... 59 2e-08
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 59 2e-08
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap... 59 2e-08
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap... 59 2e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 59 2e-08
gi|38044112 restin isoform b [Homo sapiens] 58 3e-08
gi|4506751 restin isoform a [Homo sapiens] 58 3e-08
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 58 3e-08
gi|58530840 desmoplakin isoform I [Homo sapiens] 58 4e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 57 7e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 57 7e-08
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 57 7e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 57 1e-07
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 57 1e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 1e-07
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 56 1e-07
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 56 2e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 55 2e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 4e-07
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 55 4e-07
gi|71061468 centromere protein E [Homo sapiens] 54 6e-07
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 54 6e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 54 8e-07
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] 54 8e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 53 1e-06
>gi|39725957 DAZ interacting protein 1 isoform 2 [Homo sapiens]
Length = 867
Score = 1730 bits (4481), Expect = 0.0
Identities = 867/867 (100%), Positives = 867/867 (100%)
Query: 1 MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQF 60
MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQF
Sbjct: 1 MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQF 60
Query: 61 RPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKL 120
RPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKL
Sbjct: 61 RPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKL 120
Query: 121 IRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR 180
IRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR
Sbjct: 121 IRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR 180
Query: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR 240
KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR
Sbjct: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR 240
Query: 241 SEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDE 300
SEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDE
Sbjct: 241 SEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDE 300
Query: 301 MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDF 360
MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDF
Sbjct: 301 MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDF 360
Query: 361 HNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEE 420
HNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEE
Sbjct: 361 HNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEE 420
Query: 421 LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALH 480
LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALH
Sbjct: 421 LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALH 480
Query: 481 TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKG 540
TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKG
Sbjct: 481 TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKG 540
Query: 541 LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH 600
LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH
Sbjct: 541 LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH 600
Query: 601 QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIK 660
QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIK
Sbjct: 601 QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIK 660
Query: 661 KNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSD 720
KNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSD
Sbjct: 661 KNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSD 720
Query: 721 ADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ 780
ADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ
Sbjct: 721 ADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ 780
Query: 781 ELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKG 840
ELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKG
Sbjct: 781 ELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKG 840
Query: 841 EGLQENESSTLKSSLVTVTDWSDTSDV 867
EGLQENESSTLKSSLVTVTDWSDTSDV
Sbjct: 841 EGLQENESSTLKSSLVTVTDWSDTSDV 867
>gi|7662436 DAZ interacting protein 1 isoform 1 [Homo sapiens]
Length = 848
Score = 1677 bits (4343), Expect = 0.0
Identities = 847/867 (97%), Positives = 848/867 (97%), Gaps = 19/867 (2%)
Query: 1 MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQF 60
MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQF
Sbjct: 1 MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQF 60
Query: 61 RPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKL 120
RPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKL
Sbjct: 61 RPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKL 120
Query: 121 IRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR 180
IRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR
Sbjct: 121 IRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR 180
Query: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR 240
KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR
Sbjct: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR 240
Query: 241 SEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDE 300
SEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDE
Sbjct: 241 SEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDE 300
Query: 301 MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDF 360
MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDF
Sbjct: 301 MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDF 360
Query: 361 HNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEE 420
HNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEE
Sbjct: 361 HNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEE 420
Query: 421 LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALH 480
LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPK +NAPALH
Sbjct: 421 LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPK-------------------VNAPALH 461
Query: 481 TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKG 540
TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKG
Sbjct: 462 TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKG 521
Query: 541 LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH 600
LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH
Sbjct: 522 LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH 581
Query: 601 QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIK 660
QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIK
Sbjct: 582 QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIK 641
Query: 661 KNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSD 720
KNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSD
Sbjct: 642 KNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSD 701
Query: 721 ADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ 780
ADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ
Sbjct: 702 ADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ 761
Query: 781 ELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKG 840
ELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKG
Sbjct: 762 ELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKG 821
Query: 841 EGLQENESSTLKSSLVTVTDWSDTSDV 867
EGLQENESSTLKSSLVTVTDWSDTSDV
Sbjct: 822 EGLQENESSTLKSSLVTVTDWSDTSDV 848
>gi|27734911 DAZ interacting protein 1-like [Homo sapiens]
Length = 767
Score = 330 bits (847), Expect = 3e-90
Identities = 256/792 (32%), Positives = 396/792 (50%), Gaps = 106/792 (13%)
Query: 46 APPSAASGPL------PFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFC 99
A SGPL P F+F+PR +S+DWRR+S +DVD+VA +DV TLQENI ITFC
Sbjct: 6 ATAEGLSGPLFGAYTFPTFKFQPRHDSMDWRRISTLDVDRVARELDVATLQENIAGITFC 65
Query: 100 KLEDEKCPHCQSGVDPVLLKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQS 159
L+ E C C VDP LLK++RLAQ IEYLLH Q+ L++ + LE RL+ S ++
Sbjct: 66 NLDREVCSRCGQPVDPALLKVLRLAQLIIEYLLHCQDCLSASVAQLEARLQTSLGQQQRG 125
Query: 160 KKLLTKQAGEIKTLKEECKRRKKMIST-QQLMIEAKA-NYYQCHFCDKAFMNQAFLQSHI 217
++ L +QA E+K ++EE +RR+KMIST QQL+++ +Y+ CH CDK FMN FL+ HI
Sbjct: 126 QQELGRQADELKGVREESRRRRKMISTLQQLLMQTGTHSYHTCHLCDKTFMNATFLRGHI 185
Query: 218 QRRHTEENSHFEYQKNAQ-IEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQK 276
QRRH + +K Q +E++ E L+ +L+ T+ ELEA A R +E E+
Sbjct: 186 QRRHAGVAEGGKQKKQEQPVEEVLEE---LRAKLKWTQGELEAQREAERQRQLQEAELIH 242
Query: 277 TKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQI 336
+E + K FD+WKE+E KL E++K+K++F EFK + +NS LE +L +Q S+ +
Sbjct: 243 QREIEAKKEFDKWKEQEWTKLYGEIDKLKKLFWDEFKNVAKQNSTLEEKLRALQ-SHSVM 301
Query: 337 KSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHI 396
+S +G+L+D E E+ ++ + + + Q+++W +V+ +H+EH EK L
Sbjct: 302 ESKLGSLRD--EESEEWLRQARELQALREKTEIQKTEWKRKVKELHEEHMAEKKELQEEN 359
Query: 397 EKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGN 456
++L+ S+ D + + +I L +LQEQ +I +Q + I+ + + I +
Sbjct: 360 QRLQASLSQDQKKAAAQSQCQISTLRAQLQEQARIIASQEEMIQSLSLRKVEGIHK---- 415
Query: 457 PLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGREN 516
VP + + EE E
Sbjct: 416 ---------------VP-------------------------------KAVDTEEDSPEE 429
Query: 517 EQKLNNNKMH-LRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLK 575
E + + ++ H + AL+ N +L K R ++E L EKLE++GI D +GIS L +
Sbjct: 430 EMEDSQDEQHKVLAALRRNPTLLKHFRPILEDTLEEKLESMGIRKDAKGISIQTLRHLES 489
Query: 576 SVESERHKQEREIPNFHQIREFLEHQVSCKIEEK-----ALLSSD-QCSV-SQMDTLSTG 628
+ +R ++ R+ F +R L +V+ + +E+ A+ D Q SV SQ L T
Sbjct: 490 LLRVQREQKARKFSEFLSLRGKLVKEVTSRAKERQENGAAVSQPDGQPSVKSQQSALVTR 549
Query: 629 EV-PK----MIQLPS-------KNRQLIRQKAVSTDRTSVPKIKKNV--MEDPFPRKSST 674
E PK + LPS RQ S + S P + P
Sbjct: 550 EAQPKTRTLQVALPSTPAEPPPPTRQSHGSHGSSLTQVSAPAPHPGLHGPSSTPPSSGPG 609
Query: 675 ITTPPFSSEEEQEDDDLIRAYASPGPLP---VPPPQNKGSFGKNTVKSDADGTEGSEIED 731
++TPPFSSEE+ E D + R P +P VP P++ D TE SE E+
Sbjct: 610 MSTPPFSSEEDSEGDRVQRVSLQPPKVPSRMVPRPKDDW---------DWSDTETSE-EN 659
Query: 732 TDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTN---VPEMFIKKEELQELKCADVE 788
+ +G V++ + +EK KP GG + +P ++ K E
Sbjct: 660 AQPPGQGSGTLVQSMVKNLEKQL--EAPAKKPAGGVSLFFMPNAGPQRAATPGRKPQLSE 717
Query: 789 DE-DWDISSLEE 799
DE D +ISSLE+
Sbjct: 718 DESDLEISSLED 729
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 60.5 bits (145), Expect = 7e-09
Identities = 133/623 (21%), Positives = 225/623 (36%), Gaps = 143/623 (22%)
Query: 142 LHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKAN---YY 198
+ + EE +RL E + +L Q ++ EE K + + + E+KA
Sbjct: 2219 IQSKEEEIRLK----EDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQL 2274
Query: 199 QCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEEL-------- 250
Q CD L S + EE H + ++ KL SE+ LK++L
Sbjct: 2275 QQKVCDTLQGENKELLSQL-----EETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLE 2329
Query: 251 -----------------------QLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFD 287
+ + +LE AS S+ +E KE+ + L
Sbjct: 2330 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLS 2389
Query: 288 RWKE-----------------EEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQ 330
+E +E E L+ + E+ + +E K+ K + L L I+
Sbjct: 2390 GKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2449
Query: 331 KSNMQIKSNIGT-LKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEK 389
K N+Q K+ + + +K + DR D+ Q L+ + + QE E
Sbjct: 2450 KENIQQKAQLDSFVKSMSSLQNDRDRIVGDY----QQLEERHLSIILEKDQLIQEAAAEN 2505
Query: 390 GRLLSHIEKLRTSMIDDLNASNVFYKKRI----EELGQRL----QEQNELIITQRQQIKD 441
+L I LR+ M DDLN+ N + E+L Q + +Q +L+ Q QQ K+
Sbjct: 2506 NKLKEEIRGLRSHM-DDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKE 2564
Query: 442 F--------------------TCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHT 481
N++ E K + + E + ++ +
Sbjct: 2565 LENKYAKLEEKLKESEEANEDLRRSFNALQEEKQD----LSKEIESLKVSISQLTRQVTA 2620
Query: 482 LETKSSLPMVHEQ------------AFSSHILEPIEELSEE---------EKGRENEQKL 520
L+ + +L + H Q A S + I EL EE +K E E KL
Sbjct: 2621 LQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKL 2680
Query: 521 NNNKMHL-----------RKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQ 569
HL A + + L + L M ++ LM E G+ A I+
Sbjct: 2681 KKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG--- 2737
Query: 570 LHRVLKSVESERHKQEREIPNFHQ-----IREF--LEHQVSCKIEEKALLSSDQCSVSQM 622
R + S+++ R E+ + ++E L+ Q E ALLS S++
Sbjct: 2738 --RSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNST 2795
Query: 623 DTLSTGEVPKM-IQLPSKNRQLI 644
+ S + K+ QL SK+ QL+
Sbjct: 2796 EENSLSHLEKLNQQLLSKDEQLL 2818
Score = 57.0 bits (136), Expect = 7e-08
Identities = 109/545 (20%), Positives = 225/545 (41%), Gaps = 88/545 (16%)
Query: 161 KLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRR 220
K T++ EI+ +K + + ++++IST Q A + QA Q+ +
Sbjct: 137 KSSTEEEMEIEKIKHKLQEKEELISTLQ-----------------AQLTQA--QAEQPAQ 177
Query: 221 HTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEA--------AHHASAVRFSKEY 272
+ E F K Q+++ I L+ +L T++E A A + VR ++
Sbjct: 178 SSTEMEEFVMMKQ-QLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDE 236
Query: 273 EMQ-------KTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQ 325
+Q +T+ + L++ R EE +E LV + V ++ +E +N L Q
Sbjct: 237 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVV-DLLQQELTAAEQRNQILSQQ 295
Query: 326 LSEIQKSNMQIKSNIGTLKDAHEFKEDR-----SPYPQDFHNVMQ----LLDSQESKWTA 376
L +++ + +++ + T ++ + ++ + FHN+ + LL+ E A
Sbjct: 296 LQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQA 355
Query: 377 ------RVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNE 430
R A+ Q+HK E SHI L+ + + +A + ++ + LQ++NE
Sbjct: 356 QAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALK----DQNSKLLQDKNE 411
Query: 431 LIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPM 490
+ Q I+ + L ++ E +P+ H +++S P
Sbjct: 412 QAVQSAQTIQQLE------------DQLQQKSKEISQFLNRLPLQQ---HETASQTSFPD 456
Query: 491 VHEQAFSSHILEPIEELSEEEKGRENEQ-KLNNNKMHLRKALKSNSSLTKGLRTMVEQNL 549
V+ + + E I L + ENE+ L + + L + N L+ + + QN
Sbjct: 457 VYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNR 516
Query: 550 -------MEKLETLGINADIRGISSDQLHR-VLKSVESERHKQER----EIPNFHQIREF 597
+ ++ + I A+ R S+++ + VL++ S++HK+ E+ + F
Sbjct: 517 TGEADREVSEISIVDI-ANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAF 575
Query: 598 LEHQVSCKIEEKALLS-SDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSV 656
L+ Q+ K E+A DQ + QM+ + + L + + + +S+
Sbjct: 576 LKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDF---PLMPNEESSL 632
Query: 657 PKIKK 661
P ++K
Sbjct: 633 PAVEK 637
Score = 53.1 bits (126), Expect = 1e-06
Identities = 121/569 (21%), Positives = 230/569 (40%), Gaps = 129/569 (22%)
Query: 157 EQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSH 216
++ ++LL ++ E+K L+++C R ++ IS + ++A F+Q+
Sbjct: 2008 KELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKA----------------LEFVQTE 2051
Query: 217 IQR--RHTEEN--SHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEY 272
Q+ T+EN E++K AQ +E+ K L T+SE A A ++ KE
Sbjct: 2052 SQKDLEITKENLAQAVEHRKKAQ-----AELASFKVLLDDTQSE-AARVLADNLKLKKEL 2105
Query: 273 EMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQ-- 330
+ K + +K D E E+ ++ K K+ ++ L + LE + EIQ
Sbjct: 2106 QSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVT 2165
Query: 331 -----KSNMQIKSNI-GTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQE 384
K Q++ N+ T+ F + S D V+ E K++ +Q+ +E
Sbjct: 2166 LNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2225
Query: 385 HK---------KEKGRLLS-HIEKLRTSMIDDLNASNVFYKKRI---------------- 418
+ K++ R +S H+E+L+ +N S + + K+I
Sbjct: 2226 IRLKEDNCSVLKDQLRQMSIHMEELK------INISRLEHDKQIWESKAQTEVQLQQKVC 2279
Query: 419 -------EELGQRLQE--------QNEL------IITQRQQIKDFTCNPLNSISEPKGN- 456
+EL +L+E QNEL + + + Q+ D + N L E KGN
Sbjct: 2280 DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLS-NSLEKCKEQKGNL 2338
Query: 457 --------------PLAWQAFES--QPAAPAVPMNAPALHTLETK-SSLPMVHEQAFSSH 499
+++ E+ Q + ++ E K SL E+A
Sbjct: 2339 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVA 2398
Query: 500 ILEPIEELSEEEKGREN--EQKLNNN---KMHLRKALKSNSSLTKGLRTMVEQNLMEKLE 554
I E ++ +E K EN Q+ N + +KA+ + L + L+T+ ++N+ +K
Sbjct: 2399 IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKA- 2457
Query: 555 TLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEKALLSS 614
QL +KS+ S ++ ++R + ++ Q+ E +S +E+ L+
Sbjct: 2458 --------------QLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQE 2500
Query: 615 DQCSVSQMDTLSTGEVPKMIQLPSKNRQL 643
+++ G M L S+N +L
Sbjct: 2501 AAAENNKLKEEIRGLRSHMDDLNSENAKL 2529
Score = 50.8 bits (120), Expect = 5e-06
Identities = 123/552 (22%), Positives = 202/552 (36%), Gaps = 90/552 (16%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMIS-- 185
+E L + L ++ LEE+L+ S E ++ E + L +E + K IS
Sbjct: 2555 LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQL 2614
Query: 186 TQQ---LMIEAKANYY--QCHFCDKAFMNQAFLQSHIQRRHTE-ENSHFEYQKNA----- 234
T+Q L E Y Q ++ + L S Q+R E E QK A
Sbjct: 2615 TRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVG 2674
Query: 235 QIE-KLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQK-----TKEEDFL----K 284
+IE KL+ E+ L + + R+E E A A EM++ TKE L +
Sbjct: 2675 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQ 2734
Query: 285 LFDRWK---EEEKEKLVDEMEKVKEMFMKEFKELT---------------------SKNS 320
F R + ++ +E++++K + KEL S NS
Sbjct: 2735 SFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNS 2794
Query: 321 ALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVM-QLLDSQESKWTARVQ 379
E LS ++K N Q+ S L ED Q F M L + ++ W +
Sbjct: 2795 TEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEK 2854
Query: 380 AIHQEHKKEKGRL--------LSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNEL 431
E K++ + ++K +S+ +D + K ++ Q QE EL
Sbjct: 2855 FRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITEL 2914
Query: 432 --IITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLP 489
+ Q Q+ +D T E + L+WQ LH L + S
Sbjct: 2915 HPLKAQLQEYQDKTKAFQIMQEELRQENLSWQ---------------HELHQLRMEKSSW 2959
Query: 490 MVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNL 549
+HE+ L I + ++ +N L + L+S+SS T+ L+ ++
Sbjct: 2960 EIHERRMKEQYLMAISDKDQQLSHLQN----------LIRELRSSSSQTQPLKVQYQRQA 3009
Query: 550 MEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEK 609
+ + ++ L L E H++E I + L S +EEK
Sbjct: 3010 SPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRI-------QQLNSNFSQLLEEK 3062
Query: 610 ALLSSDQCSVSQ 621
LS C SQ
Sbjct: 3063 NTLSIQLCDTSQ 3074
Score = 43.1 bits (100), Expect = 0.001
Identities = 69/371 (18%), Positives = 157/371 (42%), Gaps = 50/371 (13%)
Query: 116 VLLKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKE 175
+LL+ E + H E + + L +LR + + ++++K L + E++ +KE
Sbjct: 1617 ILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKE 1676
Query: 176 ECKRRKKMISTQQLMIE-------AKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHF 228
K RK S QQ ++E +A + K M + L S+ + E
Sbjct: 1677 --KMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECM-ETLLSSNASMKEELERVKM 1733
Query: 229 EYQK-NAQIEKLRSEIVVLKEELQLTRSELEAAHHASA-VRFSKEYEMQ----------- 275
EY+ + + + L SE L EE+Q + ++E A + +++++ Q
Sbjct: 1734 EYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSI 1793
Query: 276 --KTKEEDFLKLFDRWKEEEK-----------EKLVDEMEKVKEMFMKEFKELTSKNSAL 322
+T+E+D L + R E K +++ ++++ +L + + L
Sbjct: 1794 PGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINN-YLQQIDQLKERIAGL 1852
Query: 323 EYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIH 382
E + + ++ + +++ TL K+ Q+ M LL+ Q + +RV +
Sbjct: 1853 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK 1912
Query: 383 QEHKKEKG----RLLSHIEKLRTSM------IDDLNASNVFYK---KRIEELGQRLQEQN 429
+ ++EK RL++ + +L S+ + D N + K +++ L+E+
Sbjct: 1913 ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK 1972
Query: 430 ELIITQRQQIK 440
+ ++ ++ +++
Sbjct: 1973 QQLVKEKTKVE 1983
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/246 (21%), Positives = 107/246 (43%), Gaps = 37/246 (15%)
Query: 233 NAQIEKLRSEIVVLKEELQLTRSELE-------AAHHASAVRFSKEYEMQKTKEEDFLKL 285
N QI++ S + LKE + + +LE A + S + ++ + K E
Sbjct: 1898 NQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESE 1957
Query: 286 FDRWK------EEEKEKLVDEMEKVKEMFMKEF--------KELTSKNSALEYQ------ 325
K EEEK++LV E KV+ KE+ KE +K+ A E Q
Sbjct: 1958 MKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEK 2017
Query: 326 ---LSEIQKSNMQIKSNIGTLK---DAHEFKEDRSPYPQDF--HNVMQLLDSQESKWT-- 375
+ ++QK ++ + I L+ A EF + S + N+ Q ++ ++
Sbjct: 2018 QQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAEL 2077
Query: 376 ARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQ 435
A + + + + E R+L+ KL+ + + + K++ E+L +RL++ E + +
Sbjct: 2078 ASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKE 2137
Query: 436 RQQIKD 441
++ +++
Sbjct: 2138 KKNMQE 2143
Score = 41.2 bits (95), Expect = 0.004
Identities = 64/315 (20%), Positives = 127/315 (40%), Gaps = 28/315 (8%)
Query: 135 QEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEEC---KRRKKMIST--QQL 189
QE L LHT E H ++ K L + E+K EE R K+ I Q
Sbjct: 1432 QEDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAA 1488
Query: 190 MIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEK---LRSEIVVL 246
+I K + +K+ + L R T+ + E Q +AQ ++ + + +L
Sbjct: 1489 LISRKEALKE----NKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1544
Query: 247 KEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKE 306
+EE +E++ + + + + E LKL E+KEKLV E+E +K
Sbjct: 1545 QEERDKLITEMDRS-------LLENQSLSSSCES--LKLALEGLTEDKEKLVKEIESLKS 1595
Query: 307 MFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQL 366
+ E E K+ L+ + + +S + + ++ E Q+ + ++
Sbjct: 1596 SKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEK---QELYGKLRS 1652
Query: 367 LDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQ 426
++ + + ++Q QE ++ K + + K + I +L N + + G +
Sbjct: 1653 TEANKKETEKQLQEAEQEMEEMKEK-MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAK 1711
Query: 427 EQNELIITQRQQIKD 441
E E +++ +K+
Sbjct: 1712 ECMETLLSSNASMKE 1726
Score = 38.9 bits (89), Expect = 0.021
Identities = 51/302 (16%), Positives = 123/302 (40%), Gaps = 31/302 (10%)
Query: 71 RLSAIDVDKVAGAVDVLTLQENIMNITFC----KLEDEKCPHCQSGVDPVLLKLIRLAQF 126
++ ++ +K + V++ TL+E + ++ K + E+ SG+ ++ Q
Sbjct: 913 KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQI 972
Query: 127 TIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMIST 186
+ E L H + L + + +L+ + + ++ + +++ E+ LK+E K+ + T
Sbjct: 973 SKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSET 1032
Query: 187 QQLMIEA-KANYYQCHFCDKA-------FMNQAFLQSHIQRRHT----EENSHFEYQKNA 234
++ +E K N C + ++ Q + ++ +H EE E Q A
Sbjct: 1033 ERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQA 1092
Query: 235 QIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLK---------- 284
++++ + ++ L ++E+ + + +K
Sbjct: 1093 LVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCT 1152
Query: 285 -LFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTL 343
+ WK E +EK++ +EK KE K+ +E + A+ L + Q+ ++ +
Sbjct: 1153 GSSEHWKPELEEKIL-ALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREELKQQ 1208
Query: 344 KD 345
KD
Sbjct: 1209 KD 1210
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 58.9 bits (141), Expect = 2e-08
Identities = 108/594 (18%), Positives = 234/594 (39%), Gaps = 73/594 (12%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
I L +++ L Q TL E R + E+ K L E+ K C +R K ++
Sbjct: 886 ITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAEVCE-KIGCLQRFKEMAIF 944
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLK 247
++ K + N+ + + + R + + Q+ + +E L E + LK
Sbjct: 945 KIAALQKVVDNSVSLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLK 1004
Query: 248 E-------ELQLTRSELEAAHHA--SAVRFSKEYEMQKTKE----EDFLKLFDR-----W 289
E EL++T+ +L A + E M K K+ D + + +
Sbjct: 1005 EQVESINKELEITKEKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEM 1064
Query: 290 KEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEF 349
KE + + + +K+ E K++ +N LE + +E+ K N+ + L+D
Sbjct: 1065 KELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELAD 1124
Query: 350 KEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQ--EHKKEKGRLLSHIEKLRTSMIDDL 407
++ D +++ L+ E + V + + + + + +L+ ++ R ++ L
Sbjct: 1125 SVSKAVSDADRQRILE-LEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESL 1183
Query: 408 NASNVFYKKRIEE--LGQRLQEQN--------------ELIITQRQQIKDFTCNPLNSIS 451
+ Y+ + +E L +L + N E I ++ Q+++ + +
Sbjct: 1184 RMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLD 1243
Query: 452 EPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHIL----EPIEEL 507
E K L + E + A + +L + +LP+ ++ FS ++ + ++ +
Sbjct: 1244 E-KEQALYYARLEGRNRAKHLRQTIQSLRR-QFSGALPLAQQEKFSKTMIQLQNDKLKIM 1301
Query: 508 SEEEKGRENEQKLNNNKMHLRKALKSNSSL------TKGLRTMVEQNLM---EKLETLGI 558
E + ++ + + N + + LK L TKG + ++ ++ +L+ L +
Sbjct: 1302 QEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKL 1361
Query: 559 NADIRGISSD--QLHRVLKSVESERHKQEREI---PNFHQIREFLEHQVSCKIEEKALLS 613
N ++ + L+ ++ E E EI FH+ R+ Q +E + +
Sbjct: 1362 NRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIF 1421
Query: 614 SDQ----CSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKKNV 663
Q + +Q +TG +P LP N+ I ++ KIK+N+
Sbjct: 1422 DRQQNEILNAAQKFEEATGSIPDP-SLPLPNQLEI----------ALRKIKENI 1464
Score = 45.4 bits (106), Expect = 2e-04
Identities = 108/584 (18%), Positives = 234/584 (40%), Gaps = 85/584 (14%)
Query: 157 EQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSH 216
E + L ++ GE+ TL ++ K + AKA+ + K +
Sbjct: 1923 EGIRNKLKEKEGEVFTLTKQLNTLKDLF--------AKADKEKLTLQRKLKTTGMTVDQV 1974
Query: 217 IQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTR-SELEAAHHASAVRFSKEYEMQ 275
+ R E E K ++ L ++I+ ++ L R S +E H + K + ++
Sbjct: 1975 LGIRALESEKELEELKKRNLD-LENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALE 2033
Query: 276 KTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQ 335
K +D E + E E KE +L+S+N L++QL + K +
Sbjct: 2034 KQFSKDTYSKPSISGIESDDHCQREQE-----LQKENLKLSSENIELKFQLEQANKDLPR 2088
Query: 336 IKSNIGTLKDAHEF-KEDRSPYPQDFHNV------------MQLLDSQESKWTARVQAIH 382
+K+ + LK+ EF K++++ + +V ++ K +VQ +
Sbjct: 2089 LKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQREN 2148
Query: 383 QEHKKEKG---------------RLLSHIEKLRTSMIDDLNASNVFYKKRIEEL---GQR 424
++ KK G +L + +EKL+ + L+ K E++ +R
Sbjct: 2149 EQLKKASGILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGTEKIIAENER 2208
Query: 425 LQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLET 484
L+++ + ++++ N L ++E + Q E+ P L ++
Sbjct: 2209 LRKELKKETDAAEKLR-IAKNNLEILNE----KMTVQLEETGKRLQFAESRGPQLEGADS 2263
Query: 485 KSSLPMVHEQAFSSHILEPIEELSEE-----------EKGRENEQKLNNNKMHLRKALKS 533
KS +V + + + + E +++++ ++ E EQK+N L + +K
Sbjct: 2264 KSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKI 2323
Query: 534 NSSLTKGLRTMVEQNLMEKLETLGI-NADIRGISSDQLHRVLKSVESERHKQEREIPNFH 592
+ +G T EQ L +L+ L + N + ++ +H++ ++ E IP+
Sbjct: 2324 LKHVPEGAET--EQGLKRELQVLRLANHQLDKEKAELIHQI--EANKDQSGAESTIPDAD 2379
Query: 593 QIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKN-RQLIRQKAVST 651
Q++E KI++ Q +S ++ E K ++ +N ++
Sbjct: 2380 QLKE--------KIKD----LETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEIEDL 2427
Query: 652 DRTSVPKIKKNVMEDPFPRKSS-----TITTPPFSSEEEQEDDD 690
++KKN++ + +K S +T+P +SEE +++++
Sbjct: 2428 KYNYKEEVKKNILLEEKVKKLSEQLGVELTSPVAASEEFEDEEE 2471
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/242 (20%), Positives = 103/242 (42%), Gaps = 56/242 (23%)
Query: 223 EENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDF 282
EE + FE Q ++ KL +E LE A ++ R ++ + + E
Sbjct: 78 EEQAKFENQLKTKVMKLENE--------------LEMAQQSAGGRDTRFLRNEICQLEKQ 123
Query: 283 LKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQI-KSNIG 341
L E+K++ +++MEK E K ++L +N E + S++++ N ++ K N
Sbjct: 124 L--------EQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQ 175
Query: 342 TLKDAHEFKED------------------RSPYPQDFHNVMQLLDSQESKWTA--RVQAI 381
+D ++++ RS + + ++Q LD ++ A +++
Sbjct: 176 LCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQ 235
Query: 382 HQEHKKEKGRLLSHIEKL-------------RTSMIDDLNASNVFYKKRIEELGQRLQEQ 428
+QE +K + +EK+ ++ID L N Y+ +++EL L+ +
Sbjct: 236 NQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSK 295
Query: 429 NE 430
NE
Sbjct: 296 NE 297
Score = 41.2 bits (95), Expect = 0.004
Identities = 94/467 (20%), Positives = 176/467 (37%), Gaps = 73/467 (15%)
Query: 235 QIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEK 294
+++K+ ++ +E +L E E E + K + ED L D+ ++E
Sbjct: 1643 KLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQ-SQKES 1701
Query: 295 EKLVDEMEKVKEMFMKE--------FKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDA 346
+ L E++ KE + + L S+ + E Q + ++ +++++ + A
Sbjct: 1702 QCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAA--A 1759
Query: 347 HEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDD 406
E + + NV Q++D + +V+ +++ K K L + + S+ D+
Sbjct: 1760 EERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNR-ENSLTDN 1818
Query: 407 LNASNVFYKKRIEELGQRLQEQNELIITQ---RQQIKDFTCNPLNSISEPKGNPLA--WQ 461
LN N +K+ + + L+E+ E+ ++QIK T S +G PL Q
Sbjct: 1819 LNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLT-------SGLQGKPLTDNKQ 1871
Query: 462 AFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLN 521
+ + + +E PM + A EEL E+G++ + K+
Sbjct: 1872 SLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAK--------EELIRWEEGKKWQAKIE 1923
Query: 522 NNKMHLRKALKSNSSLTKGLRTMVE---------QNLMEKLETLGINAD----IRGISSD 568
+ L++ +LTK L T+ + L KL+T G+ D IR + S+
Sbjct: 1924 GIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQVLGIRALESE 1983
Query: 569 QLHRVLK----------------------SVESERHKQEREI-PNFHQIREFLEHQVSCK 605
+ LK SV + H Q R + H + + K
Sbjct: 1984 KELEELKKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSK 2043
Query: 606 IEEKALLSSDQCSVSQ-----MDTLSTGEVPKMIQLPSKNRQLIRQK 647
+ S D C Q LS+ + QL N+ L R K
Sbjct: 2044 PSISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLK 2090
Score = 37.4 bits (85), Expect = 0.061
Identities = 99/571 (17%), Positives = 218/571 (38%), Gaps = 85/571 (14%)
Query: 137 FLTSQLHTLEERLRLSHCDGEQSKKLLTKQAG---EIKTLKEECKRRKKMISTQQLMIEA 193
FL +++ LE++L + E +K L K+ ++ EE + + + ++
Sbjct: 112 FLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKK 171
Query: 194 KANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLT 253
K C Q + S + + +Y+ +Q+ K E++ +E+Q
Sbjct: 172 KNE----QLCQDIIDYQKQIDSQKETLLSRRGEDSDYR--SQLSKKNYELIQYLDEIQT- 224
Query: 254 RSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFK 313
L A+ V+ EM+K EE +E EK+ DE ++K + +
Sbjct: 225 ---LTEANEKIEVQ---NQEMRKNLEESV---------QEMEKMTDEYNRMKAIVHQT-- 267
Query: 314 ELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESK 373
+ + +++K N + + L D + K + +M ++++ +
Sbjct: 268 ---------DNVIDQLKKENDHYQLQVQELTDLLKSKNEEDD------PIMVAVNAKVEE 312
Query: 374 WTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELII 433
W + + E + + L + EKL+ + +D ++ + ++ I+E +++ E +
Sbjct: 313 WKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVE 372
Query: 434 TQRQQIKDFTC---NPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPM 490
++++ TC + N + KG Q + + + E + L
Sbjct: 373 QYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMK-IQSTLDILKEKTKEAERTAELAE 431
Query: 491 VHEQAFSSHILEPIEELSEEEKG--------------------RENE-----QKLNNNKM 525
+ ++E ++ L + E G R+ E +++N ++
Sbjct: 432 ADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLEL 491
Query: 526 HLRKALKSNSSLTK--GLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHK 583
+ L N +L + GL +L E + + + L + ++S+E ER
Sbjct: 492 KISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLD 551
Query: 584 QEREIPNFHQIREFLEHQVSCKIEEKALLSS----DQCSVSQMDTLSTGEVPKMIQLPSK 639
+++I Q R E+ L + D+ S ++D LS + M + SK
Sbjct: 552 LKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLLS---LKNMSEAQSK 608
Query: 640 N----RQLI-RQKAVSTDRTSVPKIKKNVME 665
N R+LI +++ + RT + K + + E
Sbjct: 609 NEFLSRELIEKERDLERSRTVIAKFQNKLKE 639
Score = 32.7 bits (73), Expect = 1.5
Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 23/145 (15%)
Query: 293 EKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKS-------------- 338
EKE+ ++ V F + KEL +N LE + EI ++ +++
Sbjct: 618 EKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIP 677
Query: 339 NIGTLKDAHEFKEDRSPYPQDFH---NVMQLL----DSQESKWTARVQAIHQEHKKEKGR 391
++ L +A E K + H V QL + ++ +R +AI+ + K
Sbjct: 678 SLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKAN 737
Query: 392 L-LSHIEKLRTSMIDDLNASNVFYK 415
L + H+EK TS++ SNV +K
Sbjct: 738 LKIDHLEK-ETSLLRQSEGSNVVFK 761
>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
sapiens]
Length = 436
Score = 58.9 bits (141), Expect = 2e-08
Identities = 85/372 (22%), Positives = 145/372 (38%), Gaps = 77/372 (20%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
I++LL +E Q TL + L GE+ T C++ +K +
Sbjct: 106 IQHLLSEREEALKQHKTLSQEL--------------VNLRGELVTASTTCEKLEKARNEL 151
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRS----EI 243
Q + EA F+Q H Q TE + + + EKLR E
Sbjct: 152 QTVYEA------------------FVQQH-QAEKTERENRLKEFYTREYEKLRDTYIEEA 192
Query: 244 VVLKEELQLTRSELEAAHHASAVRF----SKEYEMQKTKEEDFLKLFDRWKEEEKEKLVD 299
K +LQ L AAH S + S++ E+ K E L + E EK+ L D
Sbjct: 193 EKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLED 252
Query: 300 EMEKVKEMFMKEFKELTSKNSALEYQL-SEIQKSNMQIKSN------------IGTLKDA 346
+ + +E K+ +L S+N AL +L SE QK + K+N + +LK
Sbjct: 253 LLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAV 312
Query: 347 HEFKEDRSPYPQDFHNV-MQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMID 405
E K ++ + QD + M+ L + +++ QE+++ K R+ H+ R +
Sbjct: 313 LEIKNEKL-HQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTE 371
Query: 406 DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFES 465
K+ ++ +RL +NE ++ + C+P S
Sbjct: 372 QAVLQESLEKE--SKVNKRLSMENEELLWKLH--NGDLCSPKRS---------------- 411
Query: 466 QPAAPAVPMNAP 477
P + A+P+ +P
Sbjct: 412 -PTSSAIPLQSP 422
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
Length = 1270
Score = 58.9 bits (141), Expect = 2e-08
Identities = 85/372 (22%), Positives = 145/372 (38%), Gaps = 77/372 (20%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
I++LL +E Q TL + L GE+ T C++ +K +
Sbjct: 940 IQHLLSEREEALKQHKTLSQEL--------------VNLRGELVTASTTCEKLEKARNEL 985
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRS----EI 243
Q + EA F+Q H Q TE + + + EKLR E
Sbjct: 986 QTVYEA------------------FVQQH-QAEKTERENRLKEFYTREYEKLRDTYIEEA 1026
Query: 244 VVLKEELQLTRSELEAAHHASAVRF----SKEYEMQKTKEEDFLKLFDRWKEEEKEKLVD 299
K +LQ L AAH S + S++ E+ K E L + E EK+ L D
Sbjct: 1027 EKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLED 1086
Query: 300 EMEKVKEMFMKEFKELTSKNSALEYQL-SEIQKSNMQIKSN------------IGTLKDA 346
+ + +E K+ +L S+N AL +L SE QK + K+N + +LK
Sbjct: 1087 LLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAV 1146
Query: 347 HEFKEDRSPYPQDFHNV-MQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMID 405
E K ++ + QD + M+ L + +++ QE+++ K R+ H+ R +
Sbjct: 1147 LEIKNEKL-HQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTE 1205
Query: 406 DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFES 465
K+ ++ +RL +NE ++ + C+P S
Sbjct: 1206 QAVLQESLEKE--SKVNKRLSMENEELLWKLH--NGDLCSPKRS---------------- 1245
Query: 466 QPAAPAVPMNAP 477
P + A+P+ +P
Sbjct: 1246 -PTSSAIPLQSP 1256
>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
Length = 1216
Score = 58.9 bits (141), Expect = 2e-08
Identities = 85/372 (22%), Positives = 145/372 (38%), Gaps = 77/372 (20%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
I++LL +E Q TL + L GE+ T C++ +K +
Sbjct: 886 IQHLLSEREEALKQHKTLSQEL--------------VNLRGELVTASTTCEKLEKARNEL 931
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRS----EI 243
Q + EA F+Q H Q TE + + + EKLR E
Sbjct: 932 QTVYEA------------------FVQQH-QAEKTERENRLKEFYTREYEKLRDTYIEEA 972
Query: 244 VVLKEELQLTRSELEAAHHASAVRF----SKEYEMQKTKEEDFLKLFDRWKEEEKEKLVD 299
K +LQ L AAH S + S++ E+ K E L + E EK+ L D
Sbjct: 973 EKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLED 1032
Query: 300 EMEKVKEMFMKEFKELTSKNSALEYQL-SEIQKSNMQIKSN------------IGTLKDA 346
+ + +E K+ +L S+N AL +L SE QK + K+N + +LK
Sbjct: 1033 LLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAV 1092
Query: 347 HEFKEDRSPYPQDFHNV-MQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMID 405
E K ++ + QD + M+ L + +++ QE+++ K R+ H+ R +
Sbjct: 1093 LEIKNEKL-HQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTE 1151
Query: 406 DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFES 465
K+ ++ +RL +NE ++ + C+P S
Sbjct: 1152 QAVLQESLEKE--SKVNKRLSMENEELLWKLH--NGDLCSPKRS---------------- 1191
Query: 466 QPAAPAVPMNAP 477
P + A+P+ +P
Sbjct: 1192 -PTSSAIPLQSP 1202
>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
sapiens]
Length = 517
Score = 58.9 bits (141), Expect = 2e-08
Identities = 85/372 (22%), Positives = 145/372 (38%), Gaps = 77/372 (20%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
I++LL +E Q TL + L GE+ T C++ +K +
Sbjct: 187 IQHLLSEREEALKQHKTLSQEL--------------VNLRGELVTASTTCEKLEKARNEL 232
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRS----EI 243
Q + EA F+Q H Q TE + + + EKLR E
Sbjct: 233 QTVYEA------------------FVQQH-QAEKTERENRLKEFYTREYEKLRDTYIEEA 273
Query: 244 VVLKEELQLTRSELEAAHHASAVRF----SKEYEMQKTKEEDFLKLFDRWKEEEKEKLVD 299
K +LQ L AAH S + S++ E+ K E L + E EK+ L D
Sbjct: 274 EKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLED 333
Query: 300 EMEKVKEMFMKEFKELTSKNSALEYQL-SEIQKSNMQIKSN------------IGTLKDA 346
+ + +E K+ +L S+N AL +L SE QK + K+N + +LK
Sbjct: 334 LLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAV 393
Query: 347 HEFKEDRSPYPQDFHNV-MQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMID 405
E K ++ + QD + M+ L + +++ QE+++ K R+ H+ R +
Sbjct: 394 LEIKNEKL-HQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTE 452
Query: 406 DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFES 465
K+ ++ +RL +NE ++ + C+P S
Sbjct: 453 QAVLQESLEKE--SKVNKRLSMENEELLWKLH--NGDLCSPKRS---------------- 492
Query: 466 QPAAPAVPMNAP 477
P + A+P+ +P
Sbjct: 493 -PTSSAIPLQSP 503
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 58.9 bits (141), Expect = 2e-08
Identities = 126/620 (20%), Positives = 254/620 (40%), Gaps = 70/620 (11%)
Query: 75 IDVDKVAGAVDVLTLQENIM-----NITFCK---LEDEKCPHCQSGVDPVLLKLIRLAQF 126
+ ++KV + ++E I+ N F K L +++ C S + K LA+
Sbjct: 969 LQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAK- 1027
Query: 127 TIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMIST 186
+ + QE + S L EERL+ ++ +K K GE L+++ + I
Sbjct: 1028 ----IRNKQEVMISDL---EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Query: 187 QQLMIEAKANYYQCHFC----DKAFMNQAF-LQSHIQRRHTEENSHFEYQKNAQIEKLRS 241
+L + K Q + N A + +Q + E FE +K A K
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEK-ASRNKAEK 1139
Query: 242 EIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEK--EKLVD 299
+ L EEL+ ++ELE +A + E++ +E++ +L +EE K E +
Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQEVAELKKALEEETKNHEAQIQ 1195
Query: 300 EMEKVKEMFMKEFKELTSK----NSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSP 355
+M + ++E E + + LE ++ N ++ + L+ E +
Sbjct: 1196 DMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK-- 1253
Query: 356 YPQDFHNVMQLLDSQESKWTARV---QAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNV 412
+ LD+Q + A+V + E ++ +L + ++ + T ++++ +
Sbjct: 1254 --------RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVST-LLEEAEKKGI 1304
Query: 413 FYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAV 472
+ K L +LQ+ EL+ + +Q + + + + + E K N L Q E + A +
Sbjct: 1305 KFAKDAASLESQLQDTQELLQEETRQKLNLS-SRIRQLEEEK-NSLQEQQEEEEEARKNL 1362
Query: 473 PMNAPALHT--LETKSSL-----PMVHEQAFSSHILEPIEELSE--EEKGRENEQKLNNN 523
AL + +TK + + + +L+ E LS+ EEK + KL
Sbjct: 1363 EKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYD-KLEKT 1421
Query: 524 KMHLRKALKSNSSLTKGL--RTMVEQNLMEKLETLG-INADIRGISSDQLHRVLKSVESE 580
K L++ L LT L + V NL +K + + A+ + IS+ ++
Sbjct: 1422 KNRLQQEL---DDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA 1478
Query: 581 RHKQEREIPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKN 640
R K+ + + + E LE + + + K L + + +S D +V K + K+
Sbjct: 1479 REKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKD-----DVGKNVHELEKS 1533
Query: 641 RQLIRQKAVSTDRTSVPKIK 660
++ + Q+ V RT + +++
Sbjct: 1534 KRALEQQ-VEEMRTQLEELE 1552
Score = 50.4 bits (119), Expect = 7e-06
Identities = 115/584 (19%), Positives = 232/584 (39%), Gaps = 74/584 (12%)
Query: 129 EYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQ 188
E LL +E T LEE R H + K +L +Q L E + + ++ ++
Sbjct: 859 EELLKVKEKQTKVEGELEEMER-KHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
Query: 189 LMIEAKANYYQCHFCDKAFMNQAF------LQSHIQRRHTEENSHFEYQKNAQIEKLRSE 242
+E + + ++ NQ +Q+HIQ + + ++ Q+EK+ +E
Sbjct: 918 QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
Query: 243 IVVLKEELQLTRSELEAAHHASAVRFSK----EYEMQKTKEEDFLK-------------- 284
+ K E ++ E + + + + E Q +EE+ K
Sbjct: 978 AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
Query: 285 -LFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTL 343
L +R K+EEK + E+EK K E +L + + L+ Q+ E++ +Q+ L
Sbjct: 1038 DLEERLKKEEKTR--QELEKAKRKLDGETTDLQDQIAELQAQIDELK---LQLAKKEEEL 1092
Query: 344 KDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQ---AIHQEHKKEKGRLLSHIEKLR 400
+ A +D + + + V++ L +Q ++ + A + +K+K L +E L+
Sbjct: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 401 TSMIDDLN---ASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNP 457
T + D L+ A KR +E+ + + E QI+D ++ E
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEE----- 1207
Query: 458 LAWQAFESQPAAPAVPMNAPALHT--LETKSSLPMVHE-QAFSSHILEPIEELSEE---- 510
L+ Q +++ + N L T E + ++ + +A S H + ++ +E
Sbjct: 1208 LSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAK 1267
Query: 511 ------------EKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGI 558
EK + + +L+N L +A K K ++ E L + E L
Sbjct: 1268 VSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL-ESQLQDTQELLQE 1326
Query: 559 NADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQV----SCKIEEKALLSS 614
+ S ++ ++ + S + +QE E + R+ LE QV S + K +
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEE----EEARKNLEKQVLALQSQLADTKKKVDD 1382
Query: 615 DQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPK 658
D ++ ++ K+++ Q + +KA++ D+ K
Sbjct: 1383 DLGTIESLEEAK----KKLLKDAEALSQRLEEKALAYDKLEKTK 1422
Score = 47.4 bits (111), Expect = 6e-05
Identities = 97/547 (17%), Positives = 221/547 (40%), Gaps = 49/547 (8%)
Query: 131 LLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLM 190
L QE LE+++ +KK + G I++L+E K+ K
Sbjct: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407
Query: 191 IEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEEL 250
+E KA Y DK + LQ + + + + N + +K + +L EE
Sbjct: 1408 LEEKALAY-----DKLEKTKNRLQQELDDLTVDLDHQRQVASNLE-KKQKKFDQLLAEEK 1461
Query: 251 QLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMK 310
++ E A A KE TK + EE + +E E+ +
Sbjct: 1462 SISARYAEERDRAEAEAREKE-----TKALSLARAL-----EEALEAKEEFERQNKQLRA 1511
Query: 311 EFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQL-LDS 369
+ ++L S + + E++KS ++ + ++ E ED +D +++ + +
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 370 QESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDD--LNASNVFYKKRIEELGQRLQE 427
++++ +Q ++++++K L+ + +L + D+ A V KK++E + L+
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
Query: 428 QNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSS 487
Q E R ++ I + + + ++ + + + E++
Sbjct: 1632 QIEAANKARDEV----------IKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK 1681
Query: 488 LPMVHEQAFSSHILEPIEELSEEEKGREN-EQKLNNNKMHLRKALKSNSSLTKGLRTM-- 544
L ++ + IL+ EEL+ E+ R + EQ+ + + + S+L R +
Sbjct: 1682 L-----KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 1736
Query: 545 ----VEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH 600
+E+ L E+ + + D ++ Q+ + + +ER ++ N Q E
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS-DNARQQLERQNK 1795
Query: 601 QVSCKIE--EKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPK 658
++ K++ E A+ S + ++S ++ G++ + ++ +K R + T++ K
Sbjct: 1796 ELKAKLQELEGAVKSKFKATISALEA-KIGQLEEQLEQEAKERAAANKLVRRTEK----K 1850
Query: 659 IKKNVME 665
+K+ M+
Sbjct: 1851 LKEIFMQ 1857
Score = 46.2 bits (108), Expect = 1e-04
Identities = 73/336 (21%), Positives = 140/336 (41%), Gaps = 39/336 (11%)
Query: 146 EERLRLSHCDGEQSKKLLTKQAGEIKT-LKEECKRRKKMISTQQLM-IEAKANYYQCHFC 203
E L+ E+ K+LL KQ E++ L++E K+R +++++ M I+ K Q
Sbjct: 1577 ERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAA 1636
Query: 204 DKAFMN--------QAFL---QSHIQRRHTEENSHFEYQKNAQ--IEKLRSEIVVLKEEL 250
+KA QA + Q ++ + F K ++ ++ L +EI+ L+EEL
Sbjct: 1637 NKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEEL 1696
Query: 251 QLTR-----SELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVK 305
+ +E E A + S + E+ L+ EEE E+ ME +
Sbjct: 1697 ASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLN 1756
Query: 306 EMFMKEFKELTSKNSALEYQLSEIQKS----------NMQIKSNIGTLKDA--HEFKEDR 353
+ F K ++ + N+ L + S QKS N ++K+ + L+ A +FK
Sbjct: 1757 DRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATI 1816
Query: 354 SPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLS------HIEKLRTSMIDDL 407
S + + L+ + + A + + + KK K + H ++ + M +
Sbjct: 1817 SALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM-EKA 1875
Query: 408 NASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFT 443
NA K+++EE + N ++++ D T
Sbjct: 1876 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDAT 1911
Score = 38.9 bits (89), Expect = 0.021
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 15/181 (8%)
Query: 290 KEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEF 349
+EEE + +E+ KVKE K EL + L E Q+++ +A E
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 350 KEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNA 409
+ + Q+ ++ L+S+ + R Q + E KK + +HI+ L + ++ A
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKK----MQAHIQDLEEQLDEEEGA 965
Query: 410 SNVFYK---------KRIEELGQRLQEQNELIITQRQQIKD--FTCNPLNSISEPKGNPL 458
K++EE L++QN I +++ ++D C+ + E K L
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 459 A 459
A
Sbjct: 1026 A 1026
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 58.2 bits (139), Expect = 3e-08
Identities = 110/495 (22%), Positives = 192/495 (38%), Gaps = 65/495 (13%)
Query: 139 TSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYY 198
TSQL EE+L D + +K ++ E+K L+++ + +K I + L IE A
Sbjct: 717 TSQLKATEEKL----LDLDALRKASSEGKSEMKKLRQQLEAAEKQI--KHLEIEKNAESS 770
Query: 199 QCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELE 258
+ + + +++Q +E + E L E+ +LKE+ E
Sbjct: 771 KASSITRELQGRELKLTNLQENLSEVSQ--------VKETLEKELQILKEKFA------E 816
Query: 259 AAHHASAVRFSKEYEMQKT--KEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELT 316
A+ A +V+ S + + K KEE F + E+ +E L D K +E +E ++L
Sbjct: 817 ASEEAVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDERE-EQLI 874
Query: 317 SKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKE--------------DRSPYPQDFHN 362
LE ++EI K + S + + D KE + + + Q
Sbjct: 875 KAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIE 934
Query: 363 VMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELG 422
M + Q + A+ H+E KKE R LS +EK + + K R E
Sbjct: 935 DMTVKAEQSQQEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQE----LKARYERAT 987
Query: 423 QRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTL 482
+ ++E I+ Q+ T + L E L Q E + A
Sbjct: 988 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL--QELEE------LRKQADKAKAA 1039
Query: 483 ETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRK-ALKSNSSLTKGL 541
+T + EQ E E L+ E ++ KL N L++ LK+ L K
Sbjct: 1040 QTAEDAMQIMEQMTK----EKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSK 1095
Query: 542 RTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQ 601
+ +N +K+E + ++ Q + L +++ E K E+ E HQ
Sbjct: 1096 ELLTVEN--QKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD--EVTSHQ 1151
Query: 602 VSCKIEEKALLSSDQ 616
K+EE+ + ++Q
Sbjct: 1152 ---KLEEERSVLNNQ 1163
Score = 57.8 bits (138), Expect = 4e-08
Identities = 116/564 (20%), Positives = 234/564 (41%), Gaps = 91/564 (16%)
Query: 118 LKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEEC 177
LKL L Q + + +E L +L L+E+ E S++ ++ Q +T+ +
Sbjct: 784 LKLTNL-QENLSEVSQVKETLEKELQILKEKF------AEASEEAVSVQRSMQETVNKLH 836
Query: 178 KRRKK--MISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQK--- 232
++ ++ M+S+ + + F +K + +++ + EN E K
Sbjct: 837 QKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKA----KEKLENDIAEIMKMSG 892
Query: 233 --NAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWK 290
++Q+ K+ E+ + + +++ + +L A+ +A K E K E + +
Sbjct: 893 DNSSQLTKMNDELRLKERDVEELQLKLTKANE-NASFLQKSIEDMTVKAEQSQQEAAKKH 951
Query: 291 EEEKEKL---VDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIG-TLKDA 346
EEEK++L + ++EK E + +EL ++ E SE + + +I N+ TL D
Sbjct: 952 EEEKKELERKLSDLEKKMETSHNQCQELKAR---YERATSETKTKHEEILQNLQKTLLDT 1008
Query: 347 HE----FKEDRSPYPQDFHNVMQLLDSQESKWTAR-VQAIHQEHKKEKGRLLSHIEKLRT 401
+ +E+ S Q+ + + D ++ TA I ++ KEK L+ +E +
Sbjct: 1009 EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ 1068
Query: 402 SM------IDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKG 455
+ +D L +N+ K +EEL + EL+ + Q++++F
Sbjct: 1069 TNAKLQNELDTLKENNL---KNVEELNK----SKELLTVENQKMEEFRK----------- 1110
Query: 456 NPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRE 515
E + A + L L+ + ++ + E S +E++ +K E
Sbjct: 1111 --------EIETLKQAAAQKSQQLSALQ-EENVKLAEELGRSR------DEVTSHQKLEE 1155
Query: 516 NEQKLNNNKMHLRK--------------ALKSNSSLTKGLRTMVEQNLMEKLETLGINAD 561
LNN + ++K +L+ + S+T L T + L EKL
Sbjct: 1156 ERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAEL-EKLRNEVTVLR 1214
Query: 562 IRGISSDQLHRVLKSVESERHKQEREIPNFH-QIREFLEHQVSCKIEEKALLSSDQ-CSV 619
S+ LH V++++ES++ K E ++ N Q++E S D+
Sbjct: 1215 GENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQE 1274
Query: 620 SQMDTLSTGEVPKMIQLPSKNRQL 643
SQ+D L++ ++ L KN+ L
Sbjct: 1275 SQIDFLNS----VIVDLQRKNQDL 1294
Score = 43.9 bits (102), Expect = 6e-04
Identities = 63/293 (21%), Positives = 118/293 (40%), Gaps = 21/293 (7%)
Query: 64 LESVDWRRLSAIDVDKVAGAVDVLTLQENIMNI---TFCKLEDEKCPHCQSGVDPVLLKL 120
L+ ++ R A A D + + E + T LED K + + + LK
Sbjct: 1023 LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1082
Query: 121 IRLAQFTIEYLLHSQEFLTSQLHTLEERLR----LSHCDGEQSKKLLTKQAGEIKTLKEE 176
L +E L S+E LT + +EE + L ++S++L Q +K +E
Sbjct: 1083 NNLKN--VEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1140
Query: 177 CKRRKKMISTQQLMIEAKANYYQCHFCDKA---FMNQAFLQSHIQRRHTEENSHFEYQKN 233
+ R ++ S Q+L E Q K F+ A + ++ S +K+
Sbjct: 1141 GRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKD 1200
Query: 234 AQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEE 293
A++EKLR+E+ VL+ E + ++ H + E K K E +K + +E
Sbjct: 1201 AELEKLRNEVTVLRGE----NASAKSLHSV-----VQTLESDKVKLELKVKNLELQLKEN 1251
Query: 294 KEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDA 346
K +L ++ + S+ L + ++Q+ N +K + + +A
Sbjct: 1252 KRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEA 1304
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 58.2 bits (139), Expect = 3e-08
Identities = 110/495 (22%), Positives = 192/495 (38%), Gaps = 65/495 (13%)
Query: 139 TSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYY 198
TSQL EE+L D + +K ++ E+K L+++ + +K I + L IE A
Sbjct: 752 TSQLKATEEKL----LDLDALRKASSEGKSEMKKLRQQLEAAEKQI--KHLEIEKNAESS 805
Query: 199 QCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELE 258
+ + + +++Q +E + E L E+ +LKE+ E
Sbjct: 806 KASSITRELQGRELKLTNLQENLSEVSQ--------VKETLEKELQILKEKFA------E 851
Query: 259 AAHHASAVRFSKEYEMQKT--KEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELT 316
A+ A +V+ S + + K KEE F + E+ +E L D K +E +E ++L
Sbjct: 852 ASEEAVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDERE-EQLI 909
Query: 317 SKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKE--------------DRSPYPQDFHN 362
LE ++EI K + S + + D KE + + + Q
Sbjct: 910 KAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIE 969
Query: 363 VMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELG 422
M + Q + A+ H+E KKE R LS +EK + + K R E
Sbjct: 970 DMTVKAEQSQQEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQE----LKARYERAT 1022
Query: 423 QRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTL 482
+ ++E I+ Q+ T + L E L Q E + A
Sbjct: 1023 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL--QELEE------LRKQADKAKAA 1074
Query: 483 ETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRK-ALKSNSSLTKGL 541
+T + EQ E E L+ E ++ KL N L++ LK+ L K
Sbjct: 1075 QTAEDAMQIMEQMTK----EKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSK 1130
Query: 542 RTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQ 601
+ +N +K+E + ++ Q + L +++ E K E+ E HQ
Sbjct: 1131 ELLTVEN--QKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD--EVTSHQ 1186
Query: 602 VSCKIEEKALLSSDQ 616
K+EE+ + ++Q
Sbjct: 1187 ---KLEEERSVLNNQ 1198
Score = 57.8 bits (138), Expect = 4e-08
Identities = 116/564 (20%), Positives = 234/564 (41%), Gaps = 91/564 (16%)
Query: 118 LKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEEC 177
LKL L Q + + +E L +L L+E+ E S++ ++ Q +T+ +
Sbjct: 819 LKLTNL-QENLSEVSQVKETLEKELQILKEKF------AEASEEAVSVQRSMQETVNKLH 871
Query: 178 KRRKK--MISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQK--- 232
++ ++ M+S+ + + F +K + +++ + EN E K
Sbjct: 872 QKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKA----KEKLENDIAEIMKMSG 927
Query: 233 --NAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWK 290
++Q+ K+ E+ + + +++ + +L A+ +A K E K E + +
Sbjct: 928 DNSSQLTKMNDELRLKERDVEELQLKLTKANE-NASFLQKSIEDMTVKAEQSQQEAAKKH 986
Query: 291 EEEKEKL---VDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIG-TLKDA 346
EEEK++L + ++EK E + +EL ++ E SE + + +I N+ TL D
Sbjct: 987 EEEKKELERKLSDLEKKMETSHNQCQELKAR---YERATSETKTKHEEILQNLQKTLLDT 1043
Query: 347 HE----FKEDRSPYPQDFHNVMQLLDSQESKWTAR-VQAIHQEHKKEKGRLLSHIEKLRT 401
+ +E+ S Q+ + + D ++ TA I ++ KEK L+ +E +
Sbjct: 1044 EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ 1103
Query: 402 SM------IDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKG 455
+ +D L +N+ K +EEL + EL+ + Q++++F
Sbjct: 1104 TNAKLQNELDTLKENNL---KNVEELNK----SKELLTVENQKMEEFRK----------- 1145
Query: 456 NPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRE 515
E + A + L L+ + ++ + E S +E++ +K E
Sbjct: 1146 --------EIETLKQAAAQKSQQLSALQ-EENVKLAEELGRSR------DEVTSHQKLEE 1190
Query: 516 NEQKLNNNKMHLRK--------------ALKSNSSLTKGLRTMVEQNLMEKLETLGINAD 561
LNN + ++K +L+ + S+T L T + L EKL
Sbjct: 1191 ERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAEL-EKLRNEVTVLR 1249
Query: 562 IRGISSDQLHRVLKSVESERHKQEREIPNFH-QIREFLEHQVSCKIEEKALLSSDQ-CSV 619
S+ LH V++++ES++ K E ++ N Q++E S D+
Sbjct: 1250 GENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQE 1309
Query: 620 SQMDTLSTGEVPKMIQLPSKNRQL 643
SQ+D L++ ++ L KN+ L
Sbjct: 1310 SQIDFLNS----VIVDLQRKNQDL 1329
Score = 43.9 bits (102), Expect = 6e-04
Identities = 63/293 (21%), Positives = 118/293 (40%), Gaps = 21/293 (7%)
Query: 64 LESVDWRRLSAIDVDKVAGAVDVLTLQENIMNI---TFCKLEDEKCPHCQSGVDPVLLKL 120
L+ ++ R A A D + + E + T LED K + + + LK
Sbjct: 1058 LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1117
Query: 121 IRLAQFTIEYLLHSQEFLTSQLHTLEERLR----LSHCDGEQSKKLLTKQAGEIKTLKEE 176
L +E L S+E LT + +EE + L ++S++L Q +K +E
Sbjct: 1118 NNLKN--VEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1175
Query: 177 CKRRKKMISTQQLMIEAKANYYQCHFCDKA---FMNQAFLQSHIQRRHTEENSHFEYQKN 233
+ R ++ S Q+L E Q K F+ A + ++ S +K+
Sbjct: 1176 GRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKD 1235
Query: 234 AQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEE 293
A++EKLR+E+ VL+ E + ++ H + E K K E +K + +E
Sbjct: 1236 AELEKLRNEVTVLRGE----NASAKSLHSV-----VQTLESDKVKLELKVKNLELQLKEN 1286
Query: 294 KEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDA 346
K +L ++ + S+ L + ++Q+ N +K + + +A
Sbjct: 1287 KRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEA 1339
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 58.2 bits (139), Expect = 3e-08
Identities = 81/364 (22%), Positives = 145/364 (39%), Gaps = 48/364 (13%)
Query: 136 EFLTSQLHTLEERLRLSHCDGEQSKKLLTKQ--------AGEIKTLKEECKRRKKMISTQ 187
E L +Q+ L++ L + + S + L Q E++ L+E+ ++R K +
Sbjct: 571 EDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLK-- 628
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLK 247
EA +Q +K Q L++H+Q++H+ E + K+A E + + ++
Sbjct: 629 ----EAHVLAFQTMEEEKE-KEQRALENHLQQKHSAE---LQSLKDAHRESMEGFRIEME 680
Query: 248 EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWK----EEEKEKLVDEMEK 303
+ELQ R ELE A E Q D L+ + + E E+ +D +
Sbjct: 681 QELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRR 740
Query: 304 VKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNV 363
+ + +L + E+ +SE+ K + NI L EFK + N
Sbjct: 741 QSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQ 800
Query: 364 MQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKL---RTSMIDDLNASNVFYKKRIEE 420
L+ E K+ R E K E ++++ ++ + R +I L N FY
Sbjct: 801 QIRLEEMEEKYLMR------ESKPEDIQMITELKAMLTERDQIIKKLIEDNKFY------ 848
Query: 421 LGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALH 480
Q EL+ + K F +P + NPLA Q ++ + ++ P L
Sbjct: 849 -------QLELVNRETNFNKVFNSSPTVGVI----NPLAKQKKKNDKSPTNRFVSVPNLS 897
Query: 481 TLET 484
LE+
Sbjct: 898 ALES 901
Score = 55.8 bits (133), Expect = 2e-07
Identities = 108/506 (21%), Positives = 197/506 (38%), Gaps = 63/506 (12%)
Query: 131 LLHSQEFLTSQLHTLEERL---------RLSHCDGEQSKKLLTKQAGEIKTLKEECKRRK 181
LL + + S+L ERL + SH Q+ ++ Q IK L+ E R
Sbjct: 234 LLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMT--QEVTIKDLESEKSRVN 291
Query: 182 KMISTQQLMIEAKANYYQCHFCDKAFMNQAF-LQSHIQRRHTEENSHFEYQKNAQIEKLR 240
+ +S QL E + D+ Q L+ + + ++E + +L
Sbjct: 292 ERLS--QLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 349
Query: 241 SEIVVLKEELQLTRSELEAAHH-------ASAVRFSKEYEMQKTKEEDFLKLFDRWKEEE 293
E+ L E T EL HH ++A+R K+ +M ++ + KL EE+
Sbjct: 350 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLN---LEED 406
Query: 294 KEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDR 353
K +L E+E +KE+ + + L+ + + ++ + I +L+D+ E ++
Sbjct: 407 KNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNE 466
Query: 354 SPYPQD--------FHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMID 405
+D NV L+ + + + A+ +E K + ++ +E T
Sbjct: 467 LDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTE--- 523
Query: 406 DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNP------------LNSISEP 453
N K R EEL + +E + ++Q Q+KD N LN IS
Sbjct: 524 --NLRQECSKLR-EELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLL 580
Query: 454 KGNPLAWQAFESQPAAPAV--PMNAPALHTLETKSSLPMVHEQAFSS----HIL--EPIE 505
K N L Q +SQ + + + L H+Q S H+L + +E
Sbjct: 581 KQN-LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTME 639
Query: 506 ELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLME---KLETLGINADI 562
E E+E+ + L+ ++ +G R +EQ L +LE G A +
Sbjct: 640 EEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEG-KAML 698
Query: 563 RGISSDQLHRVLKSVESERHKQEREI 588
+ S+ H+ +++ RH +E+
Sbjct: 699 ASLRSELNHQHAAAIDLLRHNHHQEL 724
Score = 34.7 bits (78), Expect = 0.39
Identities = 98/482 (20%), Positives = 191/482 (39%), Gaps = 63/482 (13%)
Query: 248 EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEE-EKEKLVDEMEKVKE 306
E++QL EA H V S+E E + K E+ L+ F + + + EK+K + +E ++
Sbjct: 17 EDMQLCA---EAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRL-ALEDLQA 72
Query: 307 MFMKEFKEL------------TSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRS 354
+E +EL + A E E++ N ++ K E E +
Sbjct: 73 AHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKL 132
Query: 355 PYPQDFH-------NVMQLLDSQESKWTARVQA-IHQEHKKEKGRLLSHIEKLRT--SMI 404
Q F+ QL ++ + + +A + +E + ++ L I KL+T M+
Sbjct: 133 NKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMV 192
Query: 405 DDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFE 464
D A ++ K + + + E N ++ ++Q+ D + +S+ K E
Sbjct: 193 QD-EAGSLLDKCQKLQTALAIAENNVQVL--QKQLDDAKEGEMALLSKHK-------EVE 242
Query: 465 SQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQ--KLNN 522
S+ AA + A + S + M+ + + I++L E EK R NE+ +L
Sbjct: 243 SELAAARERLQQQASDLVLKASHIGMLQATQMTQEV--TIKDL-ESEKSRVNERLSQLEE 299
Query: 523 NKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERH 582
+ LR S T+ L +Q ++E + + + + + R LK+++S
Sbjct: 300 ERAFLR-------SKTQSLDEEQKQQILELEKKVN---EAKRTQQEYYERELKNLQSRLE 349
Query: 583 KQEREIPNFHQ--IREF-------LEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKM 633
++ ++ H + E +E S I +K L D D L+ E
Sbjct: 350 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 409
Query: 634 IQLPSKNRQLIRQKAVSTDRTSVPKIKKNV--MEDPFPRKSSTITTPPFSSEEEQEDDDL 691
+Q +N + + + ++T + ++ V E I + S E Q + DL
Sbjct: 410 LQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDL 469
Query: 692 IR 693
+
Sbjct: 470 TK 471
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 57.8 bits (138), Expect = 4e-08
Identities = 110/535 (20%), Positives = 214/535 (40%), Gaps = 78/535 (14%)
Query: 140 SQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQ 199
++L +LEE R + DG+ +K+ L K G+IK L E+ R L E + +
Sbjct: 1074 AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITR---------LTYEIEDEKRR 1124
Query: 200 CHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEA 259
+ F Q +Q+ E + +Q KL SE + ++E ++ R +
Sbjct: 1125 RKSVEDRFDQQKNDYDQLQKARQCEKENLGWQ------KLESEKAIKEKEYEIERLRVLL 1178
Query: 260 AHHASAVRFSKEYEMQKTK-EEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSK 318
+ R EYE + K + + + + + ++ +KE+ M+ KE SK
Sbjct: 1179 QEEGTRKR---EYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQ--KEDDSK 1233
Query: 319 NSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARV 378
N L QL + + N +K I L D+ +L + E + A
Sbjct: 1234 N--LRNQLDRLSRENRDLKDEIVRLNDS-------------------ILQATEQRRRAEE 1272
Query: 379 QAIHQEH-KKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQ 437
A+ Q+ E + H+E ++ + N +K+ +EE + +Q++N+ I +
Sbjct: 1273 NALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKA 1332
Query: 438 QIKDFTCNPL---NSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQ 494
+ ++ N +S+ + N ++ + + T T L M E+
Sbjct: 1333 EFQEEAKRRWEYENELSKVRNN------YDEEIISLKNQFETEINITKTTIHQLTMQKEE 1386
Query: 495 AFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLE 554
S + + I+ L+ E + E K N + + T+ LR VE+++ ++
Sbjct: 1387 DTSGYRAQ-IDNLTRENRSLSEEIKRLKNTL---------TQTTENLR-RVEEDIQQQKA 1435
Query: 555 TLGINADIRGISSDQLHRV--LKSVESERHKQ------------EREIPNFHQIREFLEH 600
T + + +L +V +++ ES R+KQ +EI Q+ + +
Sbjct: 1436 TGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETN 1495
Query: 601 QVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKM-IQLPSKNRQLIRQKAVSTDRT 654
C +E A L Q + + ++ +T + K+ +Q R I + VS +RT
Sbjct: 1496 DRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERT 1550
Score = 46.2 bits (108), Expect = 1e-04
Identities = 119/555 (21%), Positives = 235/555 (42%), Gaps = 84/555 (15%)
Query: 139 TSQLHTLEERLRLSHCDGE---QSKKLLTKQAGEIKTLK-EECKRRKKMISTQQLMIEAK 194
T L +EE ++ G Q K+ L + ++ ++ EE R K+ + I+ K
Sbjct: 1420 TENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDK 1479
Query: 195 ANYYQC--HFCDKAFMNQAFLQSHIQRRHTEENSHFEYQK-NAQIEKLRSEIVVLKEELQ 251
+ DK ++ L+ R + ++ QK N+ + +++ V ++EL
Sbjct: 1480 NKEIERLKQLIDKETNDRKCLEDENARL---QRVQYDLQKANSSATETINKLKVQEQELT 1536
Query: 252 LTRSELEAAHHASAV------RFS---KEYEMQKTKEEDFLKLFDRWKEEE---KEKLVD 299
R + E V RF KE ++QK K E+ L R E+ ++KL +
Sbjct: 1537 RLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEE 1596
Query: 300 EMEKVKEMFMKEFKELTSKNSALEYQLSEIQK---SNMQIKSNI--GTLKDAHEFKEDRS 354
E+E ++ ++ ++T+ LE Q S ++K +++ + ++ G L++ +E+
Sbjct: 1597 ELEGMRRSLKEQAIKITNLTQQLE-QASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELR 1655
Query: 355 PYPQDFHNVM-QLLDSQESKWTARVQAIH-QEHKKEKGRLLSH----IEKLRTSMIDDLN 408
+ + QLL QES A ++ H Q+ ++K R L+ IE+L+ S+ ++L
Sbjct: 1656 RLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ-SLTENLT 1714
Query: 409 ASNVFYKKRIEEL-----------GQRLQEQNELIITQRQQIKDFTCNPL------NSIS 451
++ ++ + L + ++N I+ R Q++ L N +
Sbjct: 1715 KEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQ 1774
Query: 452 EPKGN-PLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEE 510
+ N + F+ Q + + E+K+ V ++ S +L I+ L E+
Sbjct: 1775 RERENLRQEIEKFQKQALEASNRIQ-------ESKNQCTQVVQERES--LLVKIKVL-EQ 1824
Query: 511 EKGREN--EQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSD 568
+K R E +LN K L T V+Q L + + + + +
Sbjct: 1825 DKARLQRLEDELNRAKSTLEA------------ETRVKQRLECEKQQIQNDLNQWKTQYS 1872
Query: 569 QLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEKA---LLSSDQCSVSQMDTL 625
+ ++ +ESER K ERE + E L+ ++ +IEE+ L S + + SQ++T
Sbjct: 1873 RKEEAIRKIESEREKSEREKNSLRSEIERLQAEIK-RIEERCRRKLEDSTRETQSQLETE 1931
Query: 626 ST---GEVPKMIQLP 637
+ E+ K+ Q P
Sbjct: 1932 RSRYQREIDKLRQRP 1946
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 57.0 bits (136), Expect = 7e-08
Identities = 121/560 (21%), Positives = 210/560 (37%), Gaps = 91/560 (16%)
Query: 119 KLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECK 178
+L+R Q + L E ++L + E L+ D L A ++ L E
Sbjct: 557 ELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVAD-------LRAAAVKLSALNEALA 609
Query: 179 RRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHI----QRRHT--EENSHFEYQ- 231
K ++ Q L +E + N C + A + LQ + +RR E+N+H E Q
Sbjct: 610 LDKVGLNQQLLQLEEE-NQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 668
Query: 232 -----KNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLF 286
A+++ +I KEE+Q SE A+ + + ++ K +EE +
Sbjct: 669 QKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAV 728
Query: 287 DRWKEEEKEKLVDE----------MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNM-- 334
+EKE LV E +E+ ++ ++ + L+S LE L E Q+ N
Sbjct: 729 -----QEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVI 783
Query: 335 -----QIKSNIGTLKDAHEFKE------------DRSPYPQDFHNVMQLLDSQESKWTAR 377
Q++ I T+ A E + +RS Q+ + L E +
Sbjct: 784 EVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA 843
Query: 378 VQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQN---ELIIT 434
++ H+KE +L EK R+ +L + ++ EL RL+EQ E I
Sbjct: 844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQA 903
Query: 435 QRQ----QIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPM 490
QR+ Q + C + + + L + A A + L L +
Sbjct: 904 QREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADA----SQQLERLRQDMKVQK 959
Query: 491 VHEQAFSSHILEPIEELSEEEKG------------RENEQKLNNNKMHLRKA---LKSNS 535
+ EQ + + ++E E K +E L +KM L+K LKS
Sbjct: 960 LKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQL 1019
Query: 536 SLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIR 595
+ +VEQ + EKL + + +R+ K +E E+ + Q
Sbjct: 1020 VAQDDSQRLVEQEVQEKLR-----------ETQEYNRIQKELEREKASLTLSLMEKEQRL 1068
Query: 596 EFLEHQVSCKIEEKALLSSD 615
L+ S + +E + L D
Sbjct: 1069 LVLQEADSIRQQELSALRQD 1088
Score = 46.2 bits (108), Expect = 1e-04
Identities = 99/519 (19%), Positives = 207/519 (39%), Gaps = 89/519 (17%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKR-------R 180
IE L +E LT L ++ L L E+ + L ++ + K L+E+ ++ R
Sbjct: 1639 IEELQRQKEHLTQDLERRDQELMLQK---ERIQVLEDQRTRQTKILEEDLEQIKLSLRER 1695
Query: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLR 240
+ ++TQ+ +++ +A + S QR E K ++E +
Sbjct: 1696 GRELTTQRQLMQERAE-------------EGKGPSKAQRGSLEHMKLILRDKEKEVECQQ 1742
Query: 241 SEIVVLKEELQLTRSELEAAHH----ASAVRFSKEYE-------MQKTKEEDFLKLFDRW 289
I L+E +L+ H S + +E E +Q+ +E+ LK
Sbjct: 1743 EHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELK----- 1797
Query: 290 KEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEF 349
E+ + +DE ++ +E + L + + Q +++ ++ G L+ AH
Sbjct: 1798 -EQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQ---GALEQAHMT 1853
Query: 350 KEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQ-------EHKKEKGRLLS-------- 394
++R QD + L+ + + RVQA+ + E ++++ LL+
Sbjct: 1854 LKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQ 1913
Query: 395 ---HIEKLRTSMIDDLNASNVFYKKRIEEL------GQRLQEQNELIITQRQQIKDFTCN 445
H + R L A V K+R +EL Q + Q E + + +++
Sbjct: 1914 AQEHEVETRALQDSWLQAQAVL-KERDQELEALRAESQSSRHQEEAARARAEALQE-ALG 1971
Query: 446 PLNSISEPKGNPLAWQA-----FESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHI 500
++ + K L QA E+ A ++A H+ + + +L + +
Sbjct: 1972 KAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQD--- 2028
Query: 501 LEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLG--- 557
++L +E ++ +Q L LR + L K L V++N++++ + LG
Sbjct: 2029 ----QDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQER 2084
Query: 558 INADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIRE 596
+IRG LH+ ++ ++ ++E+EI + ++
Sbjct: 2085 EEEEIRG-----LHQSVRELQLTLAQKEQEILELRETQQ 2118
Score = 41.6 bits (96), Expect = 0.003
Identities = 117/646 (18%), Positives = 242/646 (37%), Gaps = 100/646 (15%)
Query: 128 IEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
+E L Q+ Q ++E+ EQ+ L ++ GE++ KE+ +R ++ ++ +
Sbjct: 1819 LEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVE 1878
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLK 247
++A + +A L +Q++ E+ E + A + VLK
Sbjct: 1879 GRRVQALEEVLGDLRAESREQEKALLA--LQQQCAEQAQEHEVETRALQDSWLQAQAVLK 1936
Query: 248 E---ELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKV 304
E EL+ R+E +++ H ++ +Q+ + L + +++ L+++ E
Sbjct: 1937 ERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAAL-----QGKEQHLLEQAELS 1991
Query: 305 KEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVM 364
+ L + + L+ L Q + Q++ + + E ++ Y +D +
Sbjct: 1992 RS--------LEASTATLQASLDACQAHSRQLEEALRIQEG--EIQDQDLRYQEDVQQLQ 2041
Query: 365 QLLDSQESKWTARVQAIHQEHKKEKGRLL--SHIEKLRTSMIDDLNASNVFYKKRIEELG 422
Q L ++ + H++E+ +LL S ++++ +MI + N+ ++ EE+
Sbjct: 2042 QALAQRDEEL---------RHQQEREQLLEKSLAQRVQENMIQE--KQNLGQEREEEEIR 2090
Query: 423 QRLQEQNELIITQRQQIKDFT-------CNPLNSISEP-KGNPLAWQAFESQPAAPAVPM 474
Q EL +T Q+ ++ N L ++ K +P+ Q+ + P +
Sbjct: 2091 GLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQR 2150
Query: 475 NAP----ALHTLETKS----------SLPMVHEQAFSSHILEPIEELSEEEKGRENEQKL 520
AL E + +L + +A S + E L R++EQ+
Sbjct: 2151 ELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQR 2210
Query: 521 NNNKMHL-RKALKSNSSLTKGLRTMVE--------------------------------- 546
+++ L R+AL+ + G + E
Sbjct: 2211 LQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQ 2270
Query: 547 --QNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSC 604
++L + + L I+ + QL L+ VE ER K +RE Q ++S
Sbjct: 2271 RLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSL---EIS- 2326
Query: 605 KIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIR-QKAVSTDRTSVPKIKKNV 663
K + D D E+ K + L L R QK R++ +
Sbjct: 2327 KATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAG 2386
Query: 664 MEDPFPRKSSTITTPPFSSEEEQE----DDDLIRAYASPGPLPVPP 705
+ + P ++ E E D+ L ++ SPGP+ + P
Sbjct: 2387 LHHSLSHSLLAVAQAPEATVLEAETRRLDESLTQSLTSPGPVLLHP 2432
Score = 38.9 bits (89), Expect = 0.021
Identities = 106/535 (19%), Positives = 206/535 (38%), Gaps = 88/535 (16%)
Query: 134 SQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEA 193
+++ L Q+ LEERL D E K ++ T ++ +R+ ++ E
Sbjct: 1258 TRDVLRDQVQKLEERLT----DTEAEKS-------QVHTELQDLQRQLSQNQEEKSKWEG 1306
Query: 194 KANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLT 253
K N + + A LQS ++R E E Q ++ + E + + E L
Sbjct: 1307 KQNSLESELME-LHETMASLQSRLRRA---ELQRMEAQGERELLQAAKENLTAQVE-HLQ 1361
Query: 254 RSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFK 313
+ +EA ASA +E +++ + LKL + E E+E+ +++ E+ + + K
Sbjct: 1362 AAVVEARAQASAAGILEE-DLRTARSA--LKLKNEEVESERER-AQALQEQGELKVAQGK 1417
Query: 314 ELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESK 373
L + L L+E ++ ++ I L+ E ++ ++LL K
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKA----------ALELLSLDLKK 1467
Query: 374 WTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELII 433
V + QE +E +EK R+ + E L +QE+ + +
Sbjct: 1468 RNQEVD-LQQEQIQE-------LEKCRSVL---------------EHLPMAVQEREQKLT 1504
Query: 434 TQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLE----TKSSLP 489
QR+QI++ L E + N L Q E + + + L+ T L
Sbjct: 1505 VQREQIRE-----LEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLA 1559
Query: 490 MVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNL 549
+ E+ + H +E ++L +E +G+ Q++ HL L+ S + +
Sbjct: 1560 LELEE--NHHKMECQQKLIKELEGQRETQRV--ALTHLTLDLEERSQ-----ELQAQSSQ 1610
Query: 550 MEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEK 609
+ LE+ S L R L+ + E Q +I + +E L + + +++
Sbjct: 1611 IHDLES----------HSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLE-RRDQE 1659
Query: 610 ALLSSDQCSV------SQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPK 658
+L ++ V Q L + L + R+L Q+ + +R K
Sbjct: 1660 LMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK 1714
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 57.0 bits (136), Expect = 7e-08
Identities = 68/326 (20%), Positives = 145/326 (44%), Gaps = 53/326 (16%)
Query: 119 KLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECK 178
++ +L + + L ++ LT +L T E + EQ K L K E + +E K
Sbjct: 477 QIAKLQKLHEKELARKEQELTKKLQTREREFQ------EQMKVALEKSQSEYLKISQE-K 529
Query: 179 RRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAF--------LQSHIQRRHTEENS---- 226
+++ ++ ++L ++ KA + + +A L+S +++ E +
Sbjct: 530 EQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 589
Query: 227 ---HFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFL 283
H E +KN K EI V+ E+ ++ELE+ H ++++ ++ K + + +
Sbjct: 590 LAVHLEAEKN----KHNKEITVMVEK---HKTELESLKHQQDALWTEKLQVLKQQYQTEM 642
Query: 284 KLFDRWKEEEKEKLVDEME-----KVKEMFMKEFKELTSKNSALE---YQLSEIQKSNMQ 335
+ E+EKE L+ + E ++EM K ++L K + LE +LSE+ K+ +
Sbjct: 643 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHK 702
Query: 336 IKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSH 395
++ + LKD + + + +D Q++ +V +I +EH+
Sbjct: 703 LEEELSVLKDQTDKMK---------QELEAKMDEQKNHHQQQVDSIIKEHEVS------- 746
Query: 396 IEKLRTSMIDDLNASNVFYKKRIEEL 421
I++ ++ D +N + K+R + L
Sbjct: 747 IQRTEKALKDQINQLELLLKERDKHL 772
Score = 52.0 bits (123), Expect = 2e-06
Identities = 123/627 (19%), Positives = 238/627 (37%), Gaps = 87/627 (13%)
Query: 125 QFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMI 184
Q T++ L E + + + +E++ L + +Q K GE++ K + ++++ +
Sbjct: 1457 QNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL 1516
Query: 185 STQQLMIEAKANYYQCHFCDKAFMNQAF---LQSHIQRRHTEENS------HFEY---QK 232
T+ A+ + H K ++ L+++ Q++ E HF+ +K
Sbjct: 1517 ETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEK 1576
Query: 233 NAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYE----MQKTKEEDFLKLFDR 288
+ ++++ +I+ L+ ++ ++ELE KE E K+KEE+ L DR
Sbjct: 1577 DNRVKEAEEKILTLENQVYSMKAELETK--------KKELEHVNLSVKSKEEELKALEDR 1628
Query: 289 WKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQ--------LSE----IQKSNMQI 336
+ E KL + K ++ K+L S+ E Q LSE +Q+ ++
Sbjct: 1629 LESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREV 1688
Query: 337 KSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQE-------HKKEK 389
LK + + P+ NV + +E+ VQ ++E + EK
Sbjct: 1689 HILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEK 1748
Query: 390 GRLLSHIEKLRTSMIDDLNASNVFYKKRIEEL--GQRLQEQNELIITQRQQ-----IKDF 442
+LL + + + + Y++R+ +L + Q +++ +I Q+ K +
Sbjct: 1749 EKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1808
Query: 443 TCNPLNSISEP--KGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSS-- 498
+ + + K N A Q E+ + TL+ K + EQ
Sbjct: 1809 SLIVAQHVEKEGGKNNIQAKQNLEN--------VFDDVQKTLQEKELTCQILEQKIKELD 1860
Query: 499 ---------HILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNL 549
H +E E S+ EK + +Q NK + L+ N+ K +V+ L
Sbjct: 1861 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKP--TELLEENTE-EKSKSHLVQPKL 1917
Query: 550 MEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFL--EHQVSCKIE 607
+ +E + L L E E+ K +EI + L EHQ +I
Sbjct: 1918 LSNMEA----------QHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1967
Query: 608 EKALLSSDQCSVSQ-MDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKKNVMED 666
+K + + Q + L + QL + + QK + T I K +
Sbjct: 1968 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 2027
Query: 667 PFPRKSSTITTPPFSSEEEQEDDDLIR 693
+S T + ++DDDL R
Sbjct: 2028 AELLESHQEETNQLLKKIAEKDDDLKR 2054
Score = 48.9 bits (115), Expect = 2e-05
Identities = 127/670 (18%), Positives = 268/670 (40%), Gaps = 120/670 (17%)
Query: 141 QLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEEC--KRRKKMISTQQLMIEAKANYY 198
QL L+++L D E + LLTKQ E++ K++ + I Q LM + +
Sbjct: 820 QLAQLQQKL----LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 875
Query: 199 QCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELE 258
+ K+ + + E+ +K I ++R K+E+++ +L
Sbjct: 876 EMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREG---QKKEIEILTQKLS 932
Query: 259 AAHHASAVRFSKEYEMQ-KTKEEDFLKLFDRWKEEE---KEKLVDEMEKVKEMFMKEFKE 314
A + + ++EYE + K +E+ K+ + KE + K+KL+D+ K+K+ E
Sbjct: 933 AKEDSIHI-LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991
Query: 315 LTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKW 374
L+ K ++ E+ ++N + + E+
Sbjct: 992 LSQKEKQFNAKMLEMAQANSA--------------------------GISDAVSRLETNQ 1025
Query: 375 TARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIIT 434
+++++ + H++E ++S EK ++L + I E+ +LQE+ + +
Sbjct: 1026 KEQIESLTEVHRRELNDVISIWEKKLNQQAEEL--------QEIHEI--QLQEKEQEVAE 1075
Query: 435 QRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQ 494
+Q+I F C E + W E L+ L+ + H
Sbjct: 1076 LKQKILLFGCE-----KEEMNKEITWLKEEG-------VKQDTTLNELQEQLKQKSAHVN 1123
Query: 495 AFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLE 554
+ + +E K + + +KL ++ L K+LK N T +++ L+E L+
Sbjct: 1124 SLA----------QDETKLKAHLEKL---EVDLNKSLKEN--------TFLQEQLVE-LK 1161
Query: 555 TLGINADIRGISSDQLHRVLKSVESERH--KQEREIPNFHQIREFLEHQVSCKIEEKALL 612
L D R +S +L LK+ + E K E N + LE + K+ E+ +
Sbjct: 1162 MLA-EEDKRKVS--ELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFK---KLSEELAI 1215
Query: 613 SSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKKNVMEDPFPRKS 672
D C + + L + ++I + S I + +S + K+K+ ++ K+
Sbjct: 1216 QLDIC-CKKTEALLEAKTNELINISSSKTNAILSR-ISHCQHRTTKVKEALL-----IKT 1268
Query: 673 STITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSDADGTEGSEIEDT 732
T++ + E+ + + + +N+ ++K+D + S + +
Sbjct: 1269 CTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQ----IKSMKADIE----SLVTEK 1320
Query: 733 DDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQELKCADVEDEDW 792
+ K G + +EK + +K +++ N+ + + KEEL+E K
Sbjct: 1321 EALQKEGGNQQQAASEKESCITQLKKELSE-----NINAVTLMKEELKEKKV-------- 1367
Query: 793 DISSLEEEIS 802
+ISSL ++++
Sbjct: 1368 EISSLSKQLT 1377
Score = 46.6 bits (109), Expect = 1e-04
Identities = 95/467 (20%), Positives = 177/467 (37%), Gaps = 66/467 (14%)
Query: 77 VDKVAGAVDVLTLQENIMNITFCK----LEDEKCPHCQSGVDPVLLKLIRLAQFTIEYLL 132
V ++ + LT ++N +NI+F + LE+++ I+ + IE L+
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKE-------------NQIKSMKADIESLV 1317
Query: 133 HSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIE 192
+E L + ++ Q KK L++ + +KEE K +K IS+
Sbjct: 1318 TEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS------ 1371
Query: 193 AKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQL 252
+++ ++Q +NS +K A I LR + K EL
Sbjct: 1372 ---------------LSKQLTDLNVQL----QNSISLSEKEAAISSLRKQYDEEKCELLD 1412
Query: 253 TRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMK-- 310
+L SKE + +D+ F WK++ + + VKE+ ++
Sbjct: 1413 QVQDLSF----KVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE 1468
Query: 311 -EFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDS 369
+ KE K+ + E+ + N + G E ++D+S + N+ L S
Sbjct: 1469 LKSKEAYEKDEQINLLKEELDQQNKRFDCLKG------EMEDDKSKMEKKESNLETELKS 1522
Query: 370 QESKWTARVQAI--HQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQ---- 423
Q TAR+ + H K + L+ + K D + V + +ELG+
Sbjct: 1523 Q----TARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN 1578
Query: 424 RLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLE 483
R++E E I+T Q+ E + L+ ++ E + A + + + L
Sbjct: 1579 RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLA 1638
Query: 484 TKSSLPMVHEQAFSSHILEPIEELSEE-EKGRENEQKLNNNKMHLRK 529
A +L +EE E+ +KG E+ N K+ R+
Sbjct: 1639 ELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERE 1685
Score = 45.8 bits (107), Expect = 2e-04
Identities = 91/489 (18%), Positives = 195/489 (39%), Gaps = 62/489 (12%)
Query: 142 LHTLEERLR-----LSHCDG--EQSKKLLTKQAGEIKTLKEECKRR-KKMISTQQLMIEA 193
L TL++R++ L C + K+ T E + L+E+ R +++ + L +
Sbjct: 281 LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAE 340
Query: 194 KANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQ-KNAQIEKLRSEIVVLKEELQL 252
K K + Q + T+ H + K +I +LRS I + + +
Sbjct: 341 KTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEE 400
Query: 253 TRSELEAAHHASAVRFSKEYEM-QKTKE---------EDFLKLFDRWKEEEKEKLVDEME 302
R + E + A+ K QKT+E ++ +K ++ EEE+ L E+
Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS 460
Query: 303 KVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHN 362
+VK+ E ++ K+S E Q++++QK + + + + E + ++F
Sbjct: 461 RVKQ----EVVDVMKKSS--EEQIAKLQKLHEKELA-----RKEQELTKKLQTREREFQE 509
Query: 363 VMQL-LDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEEL 421
M++ L+ +S++ I QE ++++ L +E + +++ + + ++ +L
Sbjct: 510 QMKVALEKSQSEYLK----ISQEKEQQESLALEELELQKKAILTES-------ENKLRDL 558
Query: 422 GQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHT 481
Q + T R +I + + S+ E K + + ++ A
Sbjct: 559 QQEAE-------TYRTRILELESSLEKSLQENKNQ------------SKDLAVHLEAEKN 599
Query: 482 LETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLR-KALKSNSSLTKG 540
K MV + L+ ++ EK + +Q+ LR K + +L K
Sbjct: 600 KHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKD 659
Query: 541 LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEH 600
+ + ++ E E D++ + L L V RHK E E+ + ++
Sbjct: 660 KEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ 719
Query: 601 QVSCKIEEK 609
++ K++E+
Sbjct: 720 ELEAKMDEQ 728
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/249 (21%), Positives = 108/249 (43%), Gaps = 41/249 (16%)
Query: 205 KAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHAS 264
K+ + Q L S+++ +H + + + +KL EIV L+++L++ R E H
Sbjct: 1909 KSHLVQPKLLSNMEAQHNDLEFKLAGAEREK-QKLGKEIVRLQKDLRMLRKE----HQQE 1963
Query: 265 AVRFSKEYEMQ-----KTKEEDF-LKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSK 318
KEY+ + K ++ED LK K+ +E +K +E+ M KE +K
Sbjct: 1964 LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM-TIKETINK 2022
Query: 319 NSALEYQLSEI-QKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTAR 377
+E +L E Q+ Q+ I D + K Y ++LD++E + TA+
Sbjct: 2023 AQEVEAELLESHQEETNQLLKKIAEKDD--DLKRTAKRYE-------EILDAREEEMTAK 2073
Query: 378 VQAIHQEHKKEKGRLLSHIEK-------------------LRTSMIDDLNASNVFYKKRI 418
V+ + + ++ + + +E+ +T++I D ++++I
Sbjct: 2074 VRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQI 2133
Query: 419 EELGQRLQE 427
L RL++
Sbjct: 2134 HNLEDRLKK 2142
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 57.0 bits (136), Expect = 7e-08
Identities = 96/528 (18%), Positives = 211/528 (39%), Gaps = 67/528 (12%)
Query: 109 CQSGVDPVLLKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAG 168
C S L + ++ Q IE +++ L E L+ + E+ K +T Q
Sbjct: 1535 CLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQ 1594
Query: 169 EIKTLKEECKRRKKMISTQQ-LMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSH 227
E+ L + +K+ + Q M++AKA+ + + + + + EE S
Sbjct: 1595 EMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSF 1654
Query: 228 FEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFD 287
+ + N QI + ++++ ++K+E++ L+ ++ KT+ ++ L +
Sbjct: 1655 QKGELNVQISERKTQLTLIKQEIEKEEENLQVV--------LRQMSKHKTELKNILDMLQ 1706
Query: 288 RWKEE------EKEKLVDEMEKVKEMFMKEFKELTS-------KNSALEYQLSEIQKSNM 334
E + ++ V E+EK + ++E EL + + +E+Q +++
Sbjct: 1707 LENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR 1766
Query: 335 QIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLS 394
+I+ + E S +D + + + ++ T RV A +E+ K + S
Sbjct: 1767 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQ-TKRVLAAAEENSKME---QS 1822
Query: 395 HIEKLRTSM------IDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLN 448
++EKL ++ +D LN + I + Q+LQE+ E + N
Sbjct: 1823 NLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAV---------------N 1867
Query: 449 SISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELS 508
S+ E N Q LHT TK ++ EQ + + + I E +
Sbjct: 1868 SLQEELANVQDHLNLAKQ----------DLLHT--TKHQDVLLSEQ---TRLQKDISEWA 1912
Query: 509 EEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGIS-S 567
+ + E++ ++ + + + L + M+ Q L ++ E+ + ++
Sbjct: 1913 NRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLK 1972
Query: 568 DQLHRVLKSVESERHKQEREIPNF----HQIREFLEHQVSCKIEEKAL 611
+Q H++ K + ++ K ++ + ++R E + C+ EK L
Sbjct: 1973 EQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTL 2020
Score = 44.7 bits (104), Expect = 4e-04
Identities = 92/451 (20%), Positives = 175/451 (38%), Gaps = 28/451 (6%)
Query: 213 LQSHIQRRHTEEN--SHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSK 270
+ H++ + EE + Q ++E+L I L +E + E+E H R +
Sbjct: 1331 IMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQ 1390
Query: 271 EYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQ 330
+ + E +L + E +VDE+E +++ +K EL + L SE+
Sbjct: 1391 KDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELS 1450
Query: 331 KSNMQIKSNIGTLKDA-------HEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQ 383
+ + K+ + DA E+ Q+ + D Q A + + Q
Sbjct: 1451 CTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQ 1510
Query: 384 EHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQ------EQNELIITQRQ 437
HK ++ +L I K+ + D + +K EEL Q+LQ E+NE Q
Sbjct: 1511 -HKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEEL-QKLQKDIEMAERNEDHHLQVL 1568
Query: 438 QIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFS 497
+ + + E + + Q E + LH L+ MV +A
Sbjct: 1569 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS----MVQAKADL 1624
Query: 498 SHILEPIEELSEEEKGRENEQKLNNNKMHLRKA-LKSNSSLTKGLRTMVEQNLMEKLETL 556
L E E+ E K ++ +K L S K T+++Q + ++ E L
Sbjct: 1625 QEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENL 1684
Query: 557 GINADIRGISSDQLHRVLKSVESERHK-QEREIPNFHQIREFLEHQVSCKIEEKALLSSD 615
+ +L +L ++ E H+ Q ++ + ++ E + QV+ +EEK L
Sbjct: 1685 QVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAV-LEEKLELE-- 1741
Query: 616 QCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQ 646
++ Q+ GE+ QL ++++ I +
Sbjct: 1742 --NLQQISQQQKGEIEWQKQLLERDKREIER 1770
Score = 40.4 bits (93), Expect = 0.007
Identities = 109/573 (19%), Positives = 219/573 (38%), Gaps = 86/573 (15%)
Query: 136 EFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEA-K 194
E L+ + L+E+ + Q+K++L A E + E+ K ++ ++L E +
Sbjct: 1783 ECLSKEKEDLQEKCDIWEKKLAQTKRVLA--AAEENSKMEQSNLEKLELNVRKLQQELDQ 1840
Query: 195 ANYYQCHFCDKAFMNQAFLQ------SHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKE 248
N + + Q LQ + +Q H K + + + V+L E
Sbjct: 1841 LNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSE 1900
Query: 249 ELQLTRSELEAAHHASAVRFSKEYEMQKTK------EEDFLKL---------FDRWKEEE 293
+ +L + E A+ + +E + Q+ + EE+ LKL + +E E
Sbjct: 1901 QTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESE 1960
Query: 294 KEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDR 353
+ KL +KE + KELT + S L+ LS++ + + + TL++ + E
Sbjct: 1961 ESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV----LAAEERVRTLQEEERWCES- 2015
Query: 354 SPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVF 413
L+ S+ ++ Q+ ++ G LL+ ++K SM D +
Sbjct: 2016 -------------LEKTLSQTKRQLSEREQQLVEKSGELLA-LQKEADSMRADFSLLRNQ 2061
Query: 414 YKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVP 473
+ ++ +++ E + QR Q++ N + + + N +
Sbjct: 2062 FLTERKKAEKQVASLKEALKIQRSQLEK------NLLEQKQENSCIQK------------ 2103
Query: 474 MNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKS 533
+ T+E + + + + E +E +K N++ L +M + A+++
Sbjct: 2104 ----EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRT 2159
Query: 534 NSSLTKG-LRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIP--- 589
S K +RT + +NL + L L + + ++ L L+S++ E P
Sbjct: 2160 LKSEVKDEIRTSL-KNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEE 2218
Query: 590 --NFHQIREFLEHQVSCKIEEKALLSSDQ-------CSVSQMDTLSTGEVPKMIQLPSKN 640
NF Q+ EH + EK D+ C Q + L G+ L S
Sbjct: 2219 KLNFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGKRQTEGTLHSLR 2278
Query: 641 RQ-------LIRQKAVSTDRTSVPKIKKNVMED 666
RQ + A S S+ +++ ++ ED
Sbjct: 2279 RQVDALGELVTSTSADSASSPSLSQLESSLTED 2311
Score = 39.7 bits (91), Expect = 0.012
Identities = 63/331 (19%), Positives = 132/331 (39%), Gaps = 36/331 (10%)
Query: 110 QSGVDPVLLKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGE 169
+S +D VL K++ A+ + L + + S TL + R + ++ L +++GE
Sbjct: 1986 KSKLDQVLSKVLA-AEERVRTLQEEERWCESLEKTLSQTKRQL----SEREQQLVEKSGE 2040
Query: 170 IKTLKEECKRRKKMIST--QQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSH 227
+ L++E + S Q + E K Q +A IQR E+N
Sbjct: 2041 LLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALK--------IQRSQLEKNLL 2092
Query: 228 FEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFD 287
+ Q+N+ I+K + I ++ ++ +H A R KE + + + K
Sbjct: 2093 EQKQENSCIQKEMATIELVAQD-----------NHERARRLMKELNQMQYEYTELKKQMA 2141
Query: 288 RWKEEEKEKLV--DEME----KVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIG 341
K+ E+ ++ D M +VK+ K L L L I + N ++ +
Sbjct: 2142 NQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELE 2201
Query: 342 TLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRT 401
+LK+ F + P+ + + + + W R +A+ ++ + + RL + + +
Sbjct: 2202 SLKENLPFTMNEGPFEEKLN--FSQVHIMDEHW--RGEALREKLRHREDRLKAQLRHCMS 2257
Query: 402 SMIDDLNASNVFYKKRIEELGQRLQEQNELI 432
+ L + + L +++ EL+
Sbjct: 2258 KQAEVLIKGKRQTEGTLHSLRRQVDALGELV 2288
Score = 34.7 bits (78), Expect = 0.39
Identities = 80/391 (20%), Positives = 162/391 (41%), Gaps = 68/391 (17%)
Query: 227 HFEYQK-NAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKL 285
H E +K QI + E L+E +QL + EA + S ++ ++ L L
Sbjct: 457 HDEIEKAEQQILRATEEFKQLEEAIQLKKIS-EAGKDLLYKQLSGRLQLVNKLRQEALDL 515
Query: 286 FDRWKEEEKEKLVDEMEKVKEMFMK---------EFKELTSKNSALEYQLSEIQKSNMQI 336
+ E++K+++ + +++K++ + + + ++ S E QL + K Q+
Sbjct: 516 -ELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQL 574
Query: 337 KSNIGTL-----KDAHEFKE-----------DRSPYPQDFHNVMQLLDSQESKWTARVQA 380
+S + + K+ E K+ +D V+ L QE T + QA
Sbjct: 575 ESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGL--QEYLGTIKGQA 632
Query: 381 IHQEHKKEKGR--------LLSHIEKLRTSM-IDDLNASNVFYKKRIEELGQRLQEQNEL 431
+++ K R L+ +E+ R + I ++A N+ +K + EL LQEQ+E+
Sbjct: 633 TQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENM--RKELAELESALQEQHEV 690
Query: 432 IITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPA---LHTLETKSSL 488
+ +Q D + A+E++ A +A A LE + L
Sbjct: 691 NASLQQTQGDLS------------------AYEAELEARLNLRDAEANQLKEELEKVTRL 732
Query: 489 PMVHEQAFSSHILEPIEELSEEEKGR---ENEQKLNNNKMHLR-KALKSNSSLTKGLRTM 544
+ + A + LE + + G+ E++ N+++H + K L+ +++L K
Sbjct: 733 TQLEQSALQAE-LEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKD 791
Query: 545 VEQNLMEKLETLGINADIRGISSDQLHRVLK 575
+ +L ++ L + + D+L R LK
Sbjct: 792 FQNHLNHVVDGL-VRPEEVAARVDELRRKLK 821
Score = 31.6 bits (70), Expect = 3.3
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 14/115 (12%)
Query: 239 LRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLV 298
+ + +V L LQ T L R + E Q +D + F+R+ EE E+L
Sbjct: 226 VENPVVTLPHYLQFTIFHL---------RSLESLEGQPVTTQDRQEAFERFSLEEVERLE 276
Query: 299 DEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDA-HEFKED 352
++EK M E +EL SK + ++ K N +K K + E K D
Sbjct: 277 RDLEKK----MIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSD 327
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 56.6 bits (135), Expect = 1e-07
Identities = 116/554 (20%), Positives = 218/554 (39%), Gaps = 109/554 (19%)
Query: 146 EERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDK 205
E+++R+ D E++K+ K G++K +E + QQL K ++ + +
Sbjct: 1041 EKKVRM---DLERAKR---KLEGDLKLTQESIMDLEN--DKQQLDERLKKKDFELNALNA 1092
Query: 206 AFMNQAFLQSHIQRR---------HTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSE 256
++ L S +Q++ EE E A++EKLRS+ L EL+
Sbjct: 1093 RIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD---LSRELEEISER 1149
Query: 257 LEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKE--------------------EEKEK 296
LE A A++V + EM K +E +F K+ +E E +
Sbjct: 1150 LEEAGGATSV----QIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGE 1205
Query: 297 LVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPY 356
+D +++VK+ KE E + + + +I K+ ++ TL+D + E RS
Sbjct: 1206 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED--QMNEHRSKA 1263
Query: 357 PQDFHNVMQLLDSQESKWTARVQAIHQEHKKE-------KGRL--LSHIEKLRTSMIDDL 407
+ +V L + T + Q +KE +G+L +E L+ + +++
Sbjct: 1264 EETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEV 1323
Query: 408 NASNVF-----------------YKKRIE---ELGQRLQEQNELIITQRQQIKDFTCNPL 447
A N Y++ E EL + L + N + R + +
Sbjct: 1324 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1383
Query: 448 NSISEPKGNPLAWQAFESQPAAPAVPMNAPAL----HTLETKSSLPMV------------ 491
+ E K LA + E++ A AV +L H L+ + MV
Sbjct: 1384 EELEEAK-KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 492 --HEQAFSSHILEPIEELSEEEKGRENEQK----LNNNKMHLRKALKSNSSLTKGLRTMV 545
++ F + E ++ E + E+ QK L+ L+ A + + + +
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK-RE 1501
Query: 546 EQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHK-----QEREIPNFHQ----IRE 596
+NL E++ L G + +L +V K +E+E+ + +E E H+ +R
Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRA 1561
Query: 597 FLE-HQVSCKIEEK 609
LE +Q+ +IE K
Sbjct: 1562 QLEFNQIKAEIERK 1575
Score = 48.5 bits (114), Expect = 3e-05
Identities = 87/403 (21%), Positives = 162/403 (40%), Gaps = 63/403 (15%)
Query: 231 QKNAQIEKLRSEIVVLKEELQLT---RSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFD 287
++ ++ ++ E LKE L+ + R ELE S ++ + ++Q E+D L +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKM-VSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 288 RWKEEEKEKLVDEMEKVKEMFMK------EFKELTSKNSALEYQLSEIQKSNMQIKSNIG 341
++ + + KVKEM + ELT+K LE + SE+++ ++ +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 342 TLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRT 401
++ E++ ++ M LD +K T +A+ + H++ L + +K+ T
Sbjct: 963 KVEKEKHATENK---VKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 402 ---------SMIDDLNASNVFYKK---RIEELGQRLQ-------------EQNELIITQR 436
+DDL S KK +E ++L+ E ++ + +R
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
Query: 437 QQIKDFTCNPLNSISEPK---GNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHE 493
+ KDF N LN+ E + G+ L + E Q + A T K
Sbjct: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK-------V 1132
Query: 494 QAFSSHILEPIEELSE--EEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLME 551
+ S + +EE+SE EE G ++ NK K + K R + E L
Sbjct: 1133 EKLRSDLSRELEEISERLEEAGGATSVQIEMNK-------KREAEFQKMRRDLEEATLQH 1185
Query: 552 KLETLGI---NADI---RGISSDQLHRVLKSVESERHKQEREI 588
+ + +AD G D L RV + +E E+ + + E+
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/218 (22%), Positives = 96/218 (44%), Gaps = 22/218 (10%)
Query: 235 QIEKLRSEIVVLKEELQLTRSELEAA-HHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEE 293
++EK+R ++ K ELQ E EA+ H + E + K E KL ++ +E E
Sbjct: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1584
Query: 294 KEK-----LVDEME-------KVKEMFMKEFKELTSKNSALEYQLSEIQK----SNMQIK 337
+ K +VD ++ + + ++ K++ + +E QLS + + Q+K
Sbjct: 1585 QAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 338 SNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQ-EHKKEKGRLLSHI 396
S LKD +D D + +++ + + A ++ + + E+ R L+
Sbjct: 1645 SLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQ 1704
Query: 397 EKLRTS----MIDDLNASNVFYKKRIEELGQRLQEQNE 430
E + TS ++ N S + KK+++ +LQ + E
Sbjct: 1705 ELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 36.6 bits (83), Expect = 0.10
Identities = 99/537 (18%), Positives = 207/537 (38%), Gaps = 57/537 (10%)
Query: 157 EQSKKLLTKQAGE----IKTLKEECKRRKK-----MISTQQLMIEAKANYYQCHFCDKAF 207
E++KK L ++ E ++ + +C +K + LM++ + + DK
Sbjct: 1387 EEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQ 1446
Query: 208 MNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVR 267
N + + ++++ E S E + + L +E+ LK + + LE
Sbjct: 1447 RNFDKILAEWKQKYEESQSELESSQK-EARSLSTELFKLKNAYEESLEHLET-------- 1497
Query: 268 FSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTS----KNSALE 323
F +E K +E+ L ++ K + E+EKV++ E EL S ++LE
Sbjct: 1498 FKRE---NKNLQEEISDLTEQLGSSGKT--IHELEKVRKQLEAEKMELQSALEEAEASLE 1552
Query: 324 YQLSEIQKSNM---QIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQA 380
++ +I ++ + QIK+ I + E Q N ++++DS ++ A ++
Sbjct: 1553 HEEGKILRAQLEFNQIKAEI-----ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRS 1607
Query: 381 IHQE---HKKEKGRL------LSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNEL 431
++ KK +G L LSH ++ + + K +L ++ ++L
Sbjct: 1608 RNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDL 1667
Query: 432 -----IITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKS 486
I+ +R + L ++ E E + V + LH+ T
Sbjct: 1668 KENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL----LHSQNTSL 1723
Query: 487 SLPMVHEQAFSSHILEPIEELSEE-EKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMV 545
A S + +EE +E E +K + + + LK + L M
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM- 1782
Query: 546 EQNLMEKLETLGINAD-IRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSC 604
++N+ + ++ L D I+ + L+ +E+ + E E+ Q R +
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAEQKRNAESVKGMR 1841
Query: 605 KIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKK 661
K E + + Q + + L ++ +QL K + ++A T++ K +K
Sbjct: 1842 KSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 56.6 bits (135), Expect = 1e-07
Identities = 106/519 (20%), Positives = 214/519 (41%), Gaps = 65/519 (12%)
Query: 158 QSKKLLTKQAGEIKT-LKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSH 216
+SK+ LT+Q E+K ++EE K + M Q ++ + C + + + ++
Sbjct: 1307 KSKQALTQQLEELKRQMEEETKAKNAMAHALQ------SSRHDCDLLREQYEEEQEAKAE 1360
Query: 217 IQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSEL----EAAHHASAVRFSKEY 272
+QR ++ NS + K ++ + EEL+ + +L + A + SK
Sbjct: 1361 LQRALSKANSEVAQWRT----KYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCA 1416
Query: 273 EMQKTKEEDFLKLFDRWKEEEKEKLV-DEMEKVKEMFMKEFKELTSKNSALEYQLSEIQK 331
++KTK+ ++ D ++ E+ ++K + F K E K + +L QK
Sbjct: 1417 SLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQK 1476
Query: 332 SNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGR 391
+ + + + +++A+E D+ + + +Q S ++ A QE +K K
Sbjct: 1477 ESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKL 1536
Query: 392 LLSHIEKLRTSMIDDLNASNVFYKKRIE----ELGQRLQEQNELIITQRQQIKDFTCNPL 447
+ L+ ++ +++ S + +I EL Q E + +I + ++I+ N
Sbjct: 1537 VEQEKSDLQVAL-EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRN-- 1593
Query: 448 NSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEEL 507
+ A +A +S A N + + L + Q S+ ++
Sbjct: 1594 --------SQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSN-----RQM 1640
Query: 508 SEEEKGRENEQ-KLNNNKMHLRKALKSNSSLTKGLRTMVEQN--LMEKLETLGINADIRG 564
+E +K Q +L ++++HL AL+SN L + L + +N L+E+LE + +
Sbjct: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKV------ 1694
Query: 565 ISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEKALLSSD--QCSVSQM 622
L+ E R E+E+ + + L Q + I K L +D QC
Sbjct: 1695 --------ALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ---- 1742
Query: 623 DTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKK 661
EV IQ S+N + +KA++ ++KK
Sbjct: 1743 -----AEVENSIQ-ESRNAEEKAKKAITDAAMMAEELKK 1775
Score = 56.2 bits (134), Expect = 1e-07
Identities = 130/613 (21%), Positives = 251/613 (40%), Gaps = 100/613 (16%)
Query: 85 DVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQFTIEYLLHSQEFLTSQLHT 144
++ L+ENI +T K ++ H Q+ D +++ + + L+ L Q
Sbjct: 985 EMTALEENISKLTKEKKSLQEA-HQQTLDD------LQVEEDKVNGLIKINAKLEQQTDD 1037
Query: 145 LE---ERLRLSHCDGEQSKKLLTKQAGEIKTLKE---ECKRRKKMISTQQLMIEAKANYY 198
LE E+ + D E++K+ K G++K +E + + K+ I + E + +
Sbjct: 1038 LEGSLEQEKKLRADLERAKR---KLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQL 1094
Query: 199 QCHFCDKAFMNQAF------LQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQL 252
Q D+ + F LQ+ I+ EE E+ A+IEK RS+ L EL+
Sbjct: 1095 QAKIDDEQVHSLQFQKKIKELQARIEE--LEEEIEAEHTLRAKIEKQRSD---LARELEE 1149
Query: 253 TRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEE-------------------- 292
LE A A+ S + EM K +E +F K+ +E
Sbjct: 1150 ISERLEEASGAT----SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVA 1205
Query: 293 EKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKED 352
E + +D +++VK+ KE EL + + + + KS I+ T++D +F E
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVED--QFSEI 1263
Query: 353 RSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNV 412
++ Q + L + AR+Q + E LSH + + S+I L S
Sbjct: 1264 KAKDEQQTQLIHDL-----NMQKARLQTQNGE--------LSHRVEEKESLISQLTKSKQ 1310
Query: 413 FYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAV 472
+++EEL ++++E+ + K+ + L S S + L Q E Q A
Sbjct: 1311 ALTQQLEELKRQMEEET--------KAKNAMAHALQS-SRHDCDLLREQYEEEQEA---- 1357
Query: 473 PMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALK 532
A L +S + + ++ EEL E +K + Q+L + + A
Sbjct: 1358 --KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQEAEENTETANS 1413
Query: 533 SNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFH 592
+SL K +Q L ++E L +R + ++ H +++ ++ ++ + +
Sbjct: 1414 KCASLEK-----TKQRLQGEVEDL-----MRDL--ERSHTACATLDKKQRNFDKVLAEWK 1461
Query: 593 QIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTD 652
Q + + ++ +E LS++ + +M V ++ L +N+ L Q+ +S
Sbjct: 1462 QKLDESQAELEAAQKESRSLSTE---LFKMRNAYEEVVDQLETLRRENKNL--QEEISDL 1516
Query: 653 RTSVPKIKKNVME 665
+ + KN+ E
Sbjct: 1517 TEQIAETGKNLQE 1529
Score = 43.9 bits (102), Expect = 6e-04
Identities = 87/409 (21%), Positives = 166/409 (40%), Gaps = 46/409 (11%)
Query: 223 EENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDF 282
+E + + Q ++ E L + E L ++ LEA R +E EM
Sbjct: 886 QEKNDLQLQVQSETENLM-DAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKK 944
Query: 283 LKLFDRWKE-----EEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIK 337
L D+ ++ E + ++EK K + K L+ + +ALE +S++ K
Sbjct: 945 RNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKK--- 1001
Query: 338 SNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIE 397
+L++AH+ D +D N + ++++ + T ++ ++ KK L + +E
Sbjct: 1002 ----SLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKK----LRADLE 1053
Query: 398 KLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNS-ISEPKGN 456
+ + + DL S ++ I +L E ++ I ++ + K+F + L + I + + +
Sbjct: 1054 RAKRKLEGDLKMS----QESIMDL-----ENDKQQIEEKLKKKEFELSQLQAKIDDEQVH 1104
Query: 457 PLAWQ--AFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGR 514
L +Q E Q + A HTL K + +++ + LE I E EE G
Sbjct: 1105 SLQFQKKIKELQARIEELEEEIEAEHTLRAK----IEKQRSDLARELEEISERLEEASGA 1160
Query: 515 ENEQKLNNNK-----MHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQ 569
+ Q N K +R+ L+ + + + + + + LG D
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQI-------DN 1213
Query: 570 LHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEKALLSSDQCS 618
L RV + +E E+ + + EI + E L S IE DQ S
Sbjct: 1214 LQRVKQKLEKEKSELKMEIDDMASNIEALSKSKS-NIERTCRTVEDQFS 1261
Score = 30.0 bits (66), Expect = 9.7
Identities = 35/128 (27%), Positives = 52/128 (40%), Gaps = 16/128 (12%)
Query: 517 EQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKS 576
E K+ L + + NS L R NL +K +L DI D L L
Sbjct: 920 EAKVKELTERLEEEEEMNSELVAKKR-----NLEDKCSSL--KRDI-----DDLELTLTK 967
Query: 577 VESERHKQEREIPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGE--VPKMI 634
VE E+H E ++ N + LE +S +EK S + +D L E V +I
Sbjct: 968 VEKEKHATENKVKNLSEEMTALEENISKLTKEKK--SLQEAHQQTLDDLQVEEDKVNGLI 1025
Query: 635 QLPSKNRQ 642
++ +K Q
Sbjct: 1026 KINAKLEQ 1033
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 56.2 bits (134), Expect = 1e-07
Identities = 98/509 (19%), Positives = 201/509 (39%), Gaps = 71/509 (13%)
Query: 128 IEYLLHSQEFLTSQLHT---LEERLRLSHCDGEQSKKLLTKQAGEI----KTLKEECKRR 180
IE L ++ L+ +L+ +E L+ + ++ +L+ + EI K LK + +R
Sbjct: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 254
Query: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKL- 239
K ++ QQL EA H + A LQ+ + EEN + Q EK+
Sbjct: 255 KLLLPQQQLQAEAD------HLGKELQSVSAKLQAQV-----EENELWNRLNQQQEEKMW 303
Query: 240 RSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVD 299
R E + + E ++ E + +R E E + ++E+ + W++EEK + +
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIR---EQEEKMRRQEEMM-----WEKEEKMRRQE 355
Query: 300 EMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQD 359
EM KE M+ +E+ + +L E +I+ ++ + +E Q+
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 360 ---------FHNVMQLLDSQESKWTARVQAIHQEHK-------KEKGRLLSHIEKLRTSM 403
+ + QE K + + IH++ K +E+ + EK+R
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 404 IDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAF 463
+ +++I + +++ Q E + Q ++I++ E K W+
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE---------QEEK----MWRQE 522
Query: 464 ESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNN 523
E + + E K Q + E E++ E+EK R E+K+
Sbjct: 523 EK------IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Query: 524 KMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQL-HRVLKSVESERH 582
+ +R+ + +R E+ + E+ E + ++ +++ + K E E
Sbjct: 577 EEKIREQKEK-------IREQ-EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
Query: 583 KQEREIPNFHQIREFLEHQVSCKIEEKAL 611
QE+E Q + E +V + +E+ +
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
Score = 42.4 bits (98), Expect = 0.002
Identities = 79/373 (21%), Positives = 144/373 (38%), Gaps = 54/373 (14%)
Query: 222 TEENSHFEYQKNA--QIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSK--EYEMQKT 277
TE Y ++A Q+E +++ + ELE A A A + K Y + T
Sbjct: 140 TELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT 199
Query: 278 KEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIK 337
KE D L L E + + DE EL KN+ L+ +L ++ +I+
Sbjct: 200 KERDALSL-----ELYRNTITDE-------------ELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 338 SNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIE 397
N+ LK E + P Q L + +A++QA +E++ E
Sbjct: 242 LNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 398 KLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNP 457
K+ +++I+E +++QEQ E I Q ++I++ +
Sbjct: 301 KMWRQ------------EEKIQEWEEKIQEQEEKIREQEEKIRE------QEEKMRRQEE 342
Query: 458 LAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSH--ILEPIEELSEEEKGRE 515
+ W+ E M E + + + E + I E E++ E+EK RE
Sbjct: 343 MMWEKEEK--------MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
Query: 516 NEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLK 575
E+K + +R+ K K R E+ + E+ E + +++H K
Sbjct: 395 QEEK-RQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKIREQEKKMWRQEEKIHEQEK 451
Query: 576 SVESERHKQEREI 588
E E+ +++ E+
Sbjct: 452 IREEEKRQEQEEM 464
Score = 33.9 bits (76), Expect = 0.67
Identities = 40/220 (18%), Positives = 95/220 (43%), Gaps = 46/220 (20%)
Query: 132 LHSQEFLTSQ----------LHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRK 181
+H QE + Q +H EE++R EQ +K+ +Q +I+ +E+ + ++
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIR------EQEEKMW-RQEEKIREQEEKIREQE 536
Query: 182 KMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRS 241
+ I Q+ M++ + + EE + + Q EK+R
Sbjct: 537 EKIREQEEMMQEQEE---------------------KMGEQEEKMQEQEKMRRQEEKIRE 575
Query: 242 EIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKE-KLVDE 300
+ ++E+ + R + E + ++ EM + +EE W++EEK + ++
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEE-KIREQEEMMQEQEEKM------WEQEEKMCEQEEK 628
Query: 301 MEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNI 340
M++ +E ++ +++ + L Q ++Q+ +++ I
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 56.2 bits (134), Expect = 1e-07
Identities = 89/459 (19%), Positives = 191/459 (41%), Gaps = 50/459 (10%)
Query: 136 EFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMI--------STQ 187
E + L L E L + E ++ +++ +KE+ ++K M+ S
Sbjct: 804 EETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKD 863
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLK 247
QL+ E KA + + + Q +Q H ++R E +++ AQ+ + +++
Sbjct: 864 QLISELKATRKRLD-SELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHL 922
Query: 248 EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFL-KLFDRWKEEEKEKLVDEMEKVKE 306
+ Q R E+E H +++F KE + T+ + L K + ++E ++ + ++ +K++
Sbjct: 923 QSAQKERDEMET--HLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRR 980
Query: 307 M---FMKEFKELTSKNSA-------LEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPY 356
+ KE+ +K+ A L +L E + + +G L+ A D S
Sbjct: 981 LGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLR-AQGGSSDSS-- 1037
Query: 357 PQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMI---DDLNASNVF 413
H +Q L+++ + + +E ++ +E+ R ++ D+L S F
Sbjct: 1038 -LALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGF 1096
Query: 414 YKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVP 473
KK +RL+E N+ + + + K S + + + + ++ A V
Sbjct: 1097 RKKI-----KRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQ 1151
Query: 474 MNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQK---------LNNNK 524
+N L+ K E H+++ ++ E+EK + N K +N+
Sbjct: 1152 LNLQVQAVLQRKE-----EEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNR 1206
Query: 525 MHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIR 563
H + A S + K L+ +++L++KL+ + IR
Sbjct: 1207 RHFKAASLELSEVKKELQ--AKEHLVQKLQAEADDLQIR 1243
Score = 44.3 bits (103), Expect = 5e-04
Identities = 100/493 (20%), Positives = 186/493 (37%), Gaps = 80/493 (16%)
Query: 138 LTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANY 197
L +QL L +L+ S++ + E+ TLK+ C ++ ++ Q M+EAK
Sbjct: 438 LQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNAS 497
Query: 198 YQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEEL---QLTR 254
D + + + + E+ K+ + LR ++ L+ +L QL R
Sbjct: 498 LASSNNDLQVAEEQYQRLMAK---VEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLER 554
Query: 255 SELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKE--- 311
+ L + AS S +++ ++ +E + +L EM ++ M +
Sbjct: 555 TTLTSKLKASQAEISSLQSVRQWYQQQL-----ALAQEARVRLQGEMAHIQVGQMTQAGL 609
Query: 312 FKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQE 371
+ L +N +L QL+E Q +M+ K I
Sbjct: 610 LEHLKLENVSLSQQLTETQHRSMKEKGRI------------------------------- 638
Query: 372 SKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEEL---GQRLQEQ 428
A++Q I + ++ + I++ +T + +DL ++R+EE +RLQ
Sbjct: 639 ---AAQLQGIEADMLDQEAAFM-QIQEAKTMVEEDL-------QRRLEEFEGERERLQRM 687
Query: 429 NELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSL 488
+ + QQ++ L + L E + + AL + E
Sbjct: 688 ADSAASLEQQLEQVKLTLLQ-----RDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDA 742
Query: 489 PMVHEQAFSSHILEPIEELSEEEKGRENE-QKLNNNKMHLRKALKSNSS----LTKGLRT 543
H + + EL E RE+ L N K+ L AL++ S L +G R
Sbjct: 743 LQTHYDELQAR----LGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARR 798
Query: 544 MVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVS 603
+ E+ E ETL + I S Q+ L+ + KQ ++I +FL+ +V
Sbjct: 799 L-EEGTEETSETLEKLREELAIKSGQVEH-LQQETAALKKQMQKIK-----EQFLQQKVM 851
Query: 604 CKIEEKALLSSDQ 616
+ + S DQ
Sbjct: 852 VEAYRRDATSKDQ 864
Score = 35.0 bits (79), Expect = 0.30
Identities = 61/297 (20%), Positives = 119/297 (40%), Gaps = 69/297 (23%)
Query: 231 QKNAQIEKLRSEIVVLKEELQLTRSELEA---------AHHASAVRFSKEYEMQKTKEED 281
Q++ Q+E L+ E + L ++L LT+ L++ H+ E + + ED
Sbjct: 707 QRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASRED 766
Query: 282 FLKLFDRWK------------------------EEEKEKLVDEMEKVKE---MFMKEFKE 314
+ L K EE E+ + +EK++E + + +
Sbjct: 767 TICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEH 826
Query: 315 LTSKNSALEYQLSEIQKSNMQIKSNI------GTLKD--AHEFKEDRSPYPQDFHNVMQ- 365
L + +AL+ Q+ +I++ +Q K + T KD E K R + + Q
Sbjct: 827 LQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQE 886
Query: 366 LLDSQESKWTARVQ--AIHQE-----------------HKKEKGRLLSHIEKLR--TSMI 404
L+ K TA + +H+E +KE+ + +H++ L+ +
Sbjct: 887 LMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQM 946
Query: 405 DDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQ 461
+ +N KK+IEEL QE + I Q+Q+++ + ++ E K A++
Sbjct: 947 VAVTEANEALKKQIEEL---QQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYE 1000
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 55.8 bits (133), Expect = 2e-07
Identities = 108/506 (21%), Positives = 197/506 (38%), Gaps = 63/506 (12%)
Query: 131 LLHSQEFLTSQLHTLEERL---------RLSHCDGEQSKKLLTKQAGEIKTLKEECKRRK 181
LL + + S+L ERL + SH Q+ ++ Q IK L+ E R
Sbjct: 354 LLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMT--QEVTIKDLESEKSRVN 411
Query: 182 KMISTQQLMIEAKANYYQCHFCDKAFMNQAF-LQSHIQRRHTEENSHFEYQKNAQIEKLR 240
+ +S QL E + D+ Q L+ + + ++E + +L
Sbjct: 412 ERLS--QLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 469
Query: 241 SEIVVLKEELQLTRSELEAAHH-------ASAVRFSKEYEMQKTKEEDFLKLFDRWKEEE 293
E+ L E T EL HH ++A+R K+ +M ++ + KL EE+
Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLN---LEED 526
Query: 294 KEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDR 353
K +L E+E +KE+ + + L+ + + ++ + I +L+D+ E ++
Sbjct: 527 KNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNE 586
Query: 354 SPYPQD--------FHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMID 405
+D NV L+ + + + A+ +E K + ++ +E T
Sbjct: 587 LDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTE--- 643
Query: 406 DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNP------------LNSISEP 453
N K R EEL + +E + ++Q Q+KD N LN IS
Sbjct: 644 --NLRQECSKLR-EELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLL 700
Query: 454 KGNPLAWQAFESQPAAPAV--PMNAPALHTLETKSSLPMVHEQAFSS----HIL--EPIE 505
K N L Q +SQ + + + L H+Q S H+L + +E
Sbjct: 701 KQN-LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTME 759
Query: 506 ELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLME---KLETLGINADI 562
E E+E+ + L+ ++ +G R +EQ L +LE G A +
Sbjct: 760 EEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEG-KAML 818
Query: 563 RGISSDQLHRVLKSVESERHKQEREI 588
+ S+ H+ +++ RH +E+
Sbjct: 819 ASLRSELNHQHAAAIDLLRHNHHQEL 844
Score = 53.9 bits (128), Expect = 6e-07
Identities = 65/318 (20%), Positives = 128/318 (40%), Gaps = 31/318 (9%)
Query: 136 EFLTSQLHTLEERLRLSHCDGEQSKKLLTKQ--------AGEIKTLKEECKRRKKMISTQ 187
E L +Q+ L++ L + + S + L Q E++ L+E+ ++R K +
Sbjct: 691 EDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLK-- 748
Query: 188 QLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLK 247
EA +Q +K Q L++H+Q++H+ E + K+A E + + ++
Sbjct: 749 ----EAHVLAFQTMEEEKE-KEQRALENHLQQKHSAE---LQSLKDAHRESMEGFRIEME 800
Query: 248 EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWK----EEEKEKLVDEMEK 303
+ELQ R ELE A E Q D L+ + + E E+ +D +
Sbjct: 801 QELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRR 860
Query: 304 VKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNV 363
+ + +L + E+ +SE+ K + NI L EFK +
Sbjct: 861 QSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKG---------KEI 911
Query: 364 MQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQ 423
+++ + Q +++ +KE + + + + M D N +N K+ L
Sbjct: 912 LRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQV 971
Query: 424 RLQEQNELIITQRQQIKD 441
L+E E + + + +D
Sbjct: 972 SLEEMEEKYLMRESKPED 989
Score = 34.7 bits (78), Expect = 0.39
Identities = 98/482 (20%), Positives = 191/482 (39%), Gaps = 63/482 (13%)
Query: 248 EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEE-EKEKLVDEMEKVKE 306
E++QL EA H V S+E E + K E+ L+ F + + + EK+K + +E ++
Sbjct: 137 EDMQLCA---EAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRL-ALEDLQA 192
Query: 307 MFMKEFKEL------------TSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRS 354
+E +EL + A E E++ N ++ K E E +
Sbjct: 193 AHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKL 252
Query: 355 PYPQDFH-------NVMQLLDSQESKWTARVQA-IHQEHKKEKGRLLSHIEKLRT--SMI 404
Q F+ QL ++ + + +A + +E + ++ L I KL+T M+
Sbjct: 253 NKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMV 312
Query: 405 DDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFE 464
D A ++ K + + + E N ++ ++Q+ D + +S+ K E
Sbjct: 313 QD-EAGSLLDKCQKLQTALAIAENNVQVL--QKQLDDAKEGEMALLSKHK-------EVE 362
Query: 465 SQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQ--KLNN 522
S+ AA + A + S + M+ + + I++L E EK R NE+ +L
Sbjct: 363 SELAAARERLQQQASDLVLKASHIGMLQATQMTQEV--TIKDL-ESEKSRVNERLSQLEE 419
Query: 523 NKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERH 582
+ LR S T+ L +Q ++E + + + + + R LK+++S
Sbjct: 420 ERAFLR-------SKTQSLDEEQKQQILELEKKVN---EAKRTQQEYYERELKNLQSRLE 469
Query: 583 KQEREIPNFHQ--IREF-------LEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKM 633
++ ++ H + E +E S I +K L D D L+ E
Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 529
Query: 634 IQLPSKNRQLIRQKAVSTDRTSVPKIKKNV--MEDPFPRKSSTITTPPFSSEEEQEDDDL 691
+Q +N + + + ++T + ++ V E I + S E Q + DL
Sbjct: 530 LQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDL 589
Query: 692 IR 693
+
Sbjct: 590 TK 591
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 55.5 bits (132), Expect = 2e-07
Identities = 68/320 (21%), Positives = 140/320 (43%), Gaps = 36/320 (11%)
Query: 126 FTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMIS 185
F I+ LL S E ++ T++E +++K L K + K L+E+ K +
Sbjct: 837 FKIKPLLKSAE-TEKEMATMKEEF-------QKTKDELAKSEAKRKELEEKMVTLLKEKN 888
Query: 186 TQQLMIEAKANYYQC--HFCDKAFMNQAFLQSHIQR--RHTEENSHFEYQKNAQIEKLRS 241
QL ++++A+ C++ N+ L++ I+ EE + A+ KL
Sbjct: 889 DLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLED 948
Query: 242 EIVVLK---EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWK--EEEKEK 296
E LK ++L+LT +++E HA+ + E +E KL K +E ++
Sbjct: 949 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 1008
Query: 297 LVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPY 356
+D+++ ++ + LT + LE Q+ +++ G+L+ + + D
Sbjct: 1009 TLDDLQAEED----KVNILTKAKTKLEQQVDDLE----------GSLEQEKKLRMDLERA 1054
Query: 357 PQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKK 416
+ ++L Q + ++ +K++ + + I K I+D A + +K
Sbjct: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK-----IEDEQAVEIQLQK 1109
Query: 417 RIEELGQRLQEQNELIITQR 436
+I+EL R++E E I +R
Sbjct: 1110 KIKELQARIEELGEEIEAER 1129
Score = 48.5 bits (114), Expect = 3e-05
Identities = 97/558 (17%), Positives = 217/558 (38%), Gaps = 49/558 (8%)
Query: 139 TSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYY 198
T L + E + + + E+ + L Q E+KT +EE +R ++ Q+ ++ +A Y
Sbjct: 1231 TDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEY 1290
Query: 199 QCHFCDK-AFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSEL 257
+K A ++Q + EE H ++ L + + + L R +
Sbjct: 1291 SRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQY 1350
Query: 258 EAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTS 317
E A E + +K + + E + + +E+E+ K+ + +E
Sbjct: 1351 EEEQEGKA-----ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1405
Query: 318 KNSALEYQLSEIQKSNMQIKSNIGTLK-DAHEFKEDRSPYPQDFHNVMQLLDSQESKWTA 376
A+ + + ++K+ ++++ + L D + + N ++L + K+
Sbjct: 1406 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKY-E 1464
Query: 377 RVQAIHQEHKKEKGRLLSHIEKLRT------SMIDDLNASNVFYKKRIEELGQRLQEQNE 430
QA + +KE L + + K++ ++ L N ++ I +L +++ E +
Sbjct: 1465 ETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGK 1524
Query: 431 LIITQ---RQQIKDFTCNPLNSISEPKGN-----------PLAWQAFESQPAAPAVPMNA 476
I ++Q++ C ++ E + + L +S+ +
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 477 PALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEK--GRENEQKLN-NNKMHLRKALKS 533
+ + + + I + L ++K G NE ++ N+ L
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 534 NSSLTKGLRTMV----------EQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHK 583
N T+G+ +++L E+L + A++ ++L L+ E R
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 584 QEREIPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQL 643
E+E+ + + + L Q + I K L +D VSQ+ + EV ++IQ S+N +
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLEND---VSQLQS----EVEEVIQ-ESRNAEE 1756
Query: 644 IRQKAVSTDRTSVPKIKK 661
+KA++ ++KK
Sbjct: 1757 KAKKAITDAAMMAEELKK 1774
Score = 37.0 bits (84), Expect = 0.079
Identities = 84/465 (18%), Positives = 185/465 (39%), Gaps = 54/465 (11%)
Query: 157 EQSKKLLTKQAGE----IKTLKEECKRRKK-----MISTQQLMIEAKANYYQCHFCDKAF 207
E++KK L ++ E ++ + +C +K + LM++ + + C DK
Sbjct: 1390 EEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQ 1449
Query: 208 MNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVR 267
N + S ++++ E + E + + L +E+ +K + + +LE +
Sbjct: 1450 RNFDKVLSEWKQKYEETQAELEASQK-ESRSLSTELFKVKNVYEESLDQLETLRREN--- 1505
Query: 268 FSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLS 327
K +++ L ++ E K+ + E+EK+K+ +E E+ + E L
Sbjct: 1506 --------KNLQQEISDLTEQIAEGGKQ--IHELEKIKKQVEQEKCEIQAALEEAEASLE 1555
Query: 328 EIQKSNMQIKSNIGTLKDAHEFK--EDRSPYPQDFHNVMQLLDSQESKWTARVQAIH--- 382
+ ++I+ + +K + K E Q N +++++ +S A +++ +
Sbjct: 1556 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDAL 1615
Query: 383 QEHKKEKGRL------LSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNEL----- 431
+ KK +G L L+H +L + + + K+ L L+ Q +L
Sbjct: 1616 RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA 1675
Query: 432 IITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMV 491
I+ +R + L + E E A+ V + LHT T
Sbjct: 1676 IVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQL----LHTQNTSLINTKK 1731
Query: 492 HEQAFSSHILEPIEELSEEEKGRENE-QKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLM 550
+ S + +EE+ +E + E + +K + + + LK + L M ++NL
Sbjct: 1732 KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-KKNLE 1790
Query: 551 EKLETLGINADIRGISSDQL-----HRVLKSVESERHKQEREIPN 590
+ ++ L D ++QL + ++ +E+ + E E+ N
Sbjct: 1791 QTVKDLQHRLD----EAEQLALKGGKKQIQKLEARVRELEGEVEN 1831
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 54.7 bits (130), Expect = 4e-07
Identities = 87/471 (18%), Positives = 193/471 (40%), Gaps = 71/471 (15%)
Query: 169 EIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHI--QRRHTEENS 226
++K L + ++ ++M++ ++ +++ + + LQS + ++ +E
Sbjct: 833 KVKPLLQVSRQEEEMMAKEEELVKVREKQLAA---ENRLTEMETLQSQLMAEKLQLQEQL 889
Query: 227 HFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLF 286
E + A+ E+LR+ + K+EL+ +LEA R +K +++ +L
Sbjct: 890 QAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
Query: 287 DRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDA 346
++ +EEE + ++EKV + K+L + LE Q ++ K
Sbjct: 950 EQLEEEESARQKLQLEKVTT--EAKLKKLEEEQIILEDQNCKLAKEK------------- 994
Query: 347 HEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDD 406
+LL+ + +++T + ++EK + L+ ++ +MI D
Sbjct: 995 ------------------KLLEDRIAEFTTNL-----TEEEEKSKSLAKLKNKHEAMITD 1031
Query: 407 LNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQ 466
L E L + +++ EL T+R+ D T L+ Q E Q
Sbjct: 1032 LE----------ERLRREEKQRQELEKTRRKLEGDST-------------DLSDQIAELQ 1068
Query: 467 PAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHI-LEPIEELSEEEKGRENEQKLNNNKM 525
+ M A E +++L V E+A ++ L+ I EL E + E ++ L + +
Sbjct: 1069 AQIAELKMQL-AKKEEELQAALARVEEEAAQKNMALKKIREL--ESQISELQEDLESERA 1125
Query: 526 HLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQE 585
KA K L + L + + L + L++ ++R +++ + K++E E E
Sbjct: 1126 SRNKAEKQKRDLGEELEAL-KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 586 REIPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQL 636
+I Q +++ ++E+ + ++ Q GE+ +++
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Score = 49.7 bits (117), Expect = 1e-05
Identities = 121/592 (20%), Positives = 232/592 (39%), Gaps = 77/592 (13%)
Query: 100 KLEDEKC----PHCQSGVDPVLLKLIRLAQFTIEYLLHSQEFLT---------SQLHTLE 146
KLE+E+ +C+ + LL+ R+A+FT ++ + + + LE
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLE-DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLE 1033
Query: 147 ERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKA 206
ERLR ++ +K K G+ L ++ + I+ ++ + K
Sbjct: 1034 ERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK------------ 1081
Query: 207 FMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAV 266
+ LQ+ + R EE + + +I +L S+I L+E+L+ R+ A
Sbjct: 1082 ---EEELQAALAR--VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR- 1135
Query: 267 RFSKEYEMQKTKEEDFLKLFDRWKE--EEKEKLVDEMEKVKEMFMK----EFKELTSKNS 320
+E E KT+ ED L +E ++E+ V+ ++K E K + +E+ K+S
Sbjct: 1136 DLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS 1195
Query: 321 ALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESK------W 374
+L+E + ++K+N+ K E +R + ++Q E K
Sbjct: 1196 QAVEELAEQLEQTKRVKANLEKAKQTLE--NERGELANEVKVLLQGKGDSEHKRKKVEAQ 1253
Query: 375 TARVQAIHQEHKKEKGRLLSHIEKLR------TSMIDDLNASNVFYKKRIEELGQRLQEQ 428
+Q E ++ + L + KL+ T ++ ++ + K L +LQ+
Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 429 NELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSL 488
EL+ + +Q K L + + K N Q E + A + LH
Sbjct: 1314 QELLQEENRQ-KLSLSTKLKQVEDEK-NSFREQLEEEEEAKHNLEKQIATLHA----QVA 1367
Query: 489 PMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQN 548
M + S LE EE+ R+ ++ L + + + L K +T ++Q
Sbjct: 1368 DMKKKMEDSVGCLETAEEVK-----RKLQKDLEGLSQRHEEKVAAYDKLEK-TKTRLQQE 1421
Query: 549 LMEKLETL------GINADIRGISSDQLHRVLKSVES----ERHKQEREIPNFHQIREFL 598
L + L L N + + DQL K++ + ER + E E L
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
Query: 599 EHQVSCKIEEKALLS--SDQCSVSQMDTLST-GEVPKMIQLPSKNRQLIRQK 647
+ +E+KA L + Q D +S+ +V K + K+++ + Q+
Sbjct: 1482 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/265 (17%), Positives = 110/265 (41%), Gaps = 17/265 (6%)
Query: 143 HTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHF 202
H LE+++ H KK + G ++T +E ++ +K + E K Y
Sbjct: 1353 HNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLE 1412
Query: 203 CDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHH 262
K + Q + H +++ +K + ++L +E + + R EA
Sbjct: 1413 KTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE-- 1470
Query: 263 ASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSAL 322
+ KE L L +E ++K E+E++ + F E ++L S +
Sbjct: 1471 ------------AREKETKALSLARALEEAMEQKA--ELERLNKQFRTEMEDLMSSKDDV 1516
Query: 323 EYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQL-LDSQESKWTARVQAI 381
+ E++KS ++ + +K E ED +D +++ L + ++++ +Q
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR 1576
Query: 382 HQEHKKEKGRLLSHIEKLRTSMIDD 406
++ +++K +L+ + ++ + D+
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDE 1601
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 54.7 bits (130), Expect = 4e-07
Identities = 105/495 (21%), Positives = 200/495 (40%), Gaps = 60/495 (12%)
Query: 155 DGEQSKKLL-TKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFL 213
D EQ+ KLL TK +I LK+E S+ ++ E + N Q K + ++ L
Sbjct: 472 DYEQNMKLLQTKYDADINLLKQEHALSASKASS--MIEELEQNVCQL----KQQLQESEL 525
Query: 214 QSHIQRRHTE-----ENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRF 268
Q Q R E E SH ++ + L+SE+ KE+ Q + E A +
Sbjct: 526 QRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQL 585
Query: 269 SKEYEMQKTKEED---FLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQ 325
++ E+Q+ + + L+ F R E EK+ EM KE K +LT S E Q
Sbjct: 586 TRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEM---KEQMEKVEADLTRSKSLREKQ 642
Query: 326 LSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEH 385
E + ++ R Y Q +++L E + T + Q+H
Sbjct: 643 SKEF----------------LWQLEDIRQRYEQ---QIVELKLEHEQEKT----HLLQQH 679
Query: 386 KKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCN 445
EK L+ E+ ++ L A+N+ ++ +I+E +R ++I Q+
Sbjct: 680 NAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKR---DAQVIADMEAQVHKLREE 736
Query: 446 PLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIE 505
+N S+ K + + A + ++ L+ +S + + +H E
Sbjct: 737 LINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKI--ELKKTHAAE--T 792
Query: 506 ELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGI 565
E++ E+ + +Q L K+ + + L + ++ E+N ++L D+R
Sbjct: 793 EMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQK 852
Query: 566 SSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSC---KIEEKALLSSDQCSV--S 620
D+ ++++ + + E+ N +QV C K++ K L S +Q +
Sbjct: 853 FEDEKKQLIRDNDQAIKVLQDELEN-------RSNQVRCAEKKLQHKELESQEQITYIRQ 905
Query: 621 QMDTLSTGEVPKMIQ 635
+ +T G +P ++
Sbjct: 906 EYETKLKGLMPASLR 920
Score = 46.6 bits (109), Expect = 1e-04
Identities = 96/488 (19%), Positives = 196/488 (40%), Gaps = 54/488 (11%)
Query: 135 QEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECK----RRKKMISTQQLM 190
Q+ L + + +EE L ++++ + K +++TL +C+ ++ I+ + +
Sbjct: 284 QKILERKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKI 343
Query: 191 IEAKANYYQCHFCDKAFMNQAFLQSH---IQRRHTEENSHFEYQKNAQIEKLRSEIVVLK 247
E + K A ++ +Q++HTE N ++ K+ SE +
Sbjct: 344 CEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQT 403
Query: 248 EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVD---EMEKV 304
+ ELEA Q T E + L +++KL+ E+E+
Sbjct: 404 QSTNHMIKELEAR------------VQQLTGEAENSNL-------QRQKLIQEKAELERC 444
Query: 305 KEMFMKEFKELTSKNSALEYQLSEI---QKSNMQI-----KSNIGTLKDAHEFKEDR--S 354
++ E +E+ ++ + L + + + NM++ ++I LK H + S
Sbjct: 445 YQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASS 504
Query: 355 PYPQDFHNVMQLLDS-QESKWTARVQAIHQEHK--KEKGRLLSHIEKLRTSMIDDLNASN 411
+ NV QL QES+ + Q QE+K EK L EK + +L+
Sbjct: 505 MIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGK 564
Query: 412 VFYKKRIEELGQRLQEQNELI--ITQRQQIK----DFTCNPLNSISEPKGNPLAWQAFES 465
+K+I + + L+E+ E + +T+ Q+++ D E + + E
Sbjct: 565 EDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQ 624
Query: 466 QPAAPAVPMNAPALHTLETKSSLPMVHE--QAFSSHILEPIEELSEEEKGRENEQKLNNN 523
A + +L ++K L + + Q + I+E ++ E+EK +Q
Sbjct: 625 MEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVE-LKLEHEQEKTHLLQQHNAEK 683
Query: 524 KMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRV---LKSVESE 580
+R + +L K LR ++ + E +A + Q+H++ L +V S+
Sbjct: 684 DSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQ 743
Query: 581 RHKQEREI 588
R +Q E+
Sbjct: 744 RKQQLVEL 751
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 53.9 bits (128), Expect = 6e-07
Identities = 84/421 (19%), Positives = 178/421 (42%), Gaps = 51/421 (12%)
Query: 234 AQIEKLRSEIVVLKEELQLTRSE-----LEAAHHASAVRFSKEYEMQKTKEEDFLKLFDR 288
+++E+LR EI EEL + SE E H S V+ E E+ KTK +D
Sbjct: 754 SEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLE-EIGKTK-DDLATTQSN 811
Query: 289 WKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHE 348
+K ++E + + F +++K + +N + ++ + K + S++G LK
Sbjct: 812 YKSTDQE--FQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELS 869
Query: 349 FK----EDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLR--TS 402
+K ++++ Q+ N M+ L Q + +Q + +E +L +E+++ T
Sbjct: 870 YKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQ 929
Query: 403 MIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQA 462
DDL + ++L + + + I ++Q++ N L S+ + + ++
Sbjct: 930 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLR----NALESLKQHQETINTLKS 985
Query: 463 FESQPAAPAVPMNAPALHT----------LETKSSLPMVHEQAFSSHILEPIEELSEEEK 512
S+ + + M T ++ K L + Q ++ + + E+ E+++
Sbjct: 986 KISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKD--NEIIEQQR 1043
Query: 513 GRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHR 572
L K L++ L+S + + L+T +++N+ +E N + + D+L +
Sbjct: 1044 ---KIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIE----NQEELRLLGDELKK 1096
Query: 573 VLKSVESERHKQEREIPNFHQIREFLEHQVSC----KIEEKALLSSDQCSVSQMDTLSTG 628
+ V E++ H I++ E +C ++EEK S Q Q L+
Sbjct: 1097 QQEIVAQEKN---------HAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQ 1147
Query: 629 E 629
E
Sbjct: 1148 E 1148
Score = 48.9 bits (115), Expect = 2e-05
Identities = 133/694 (19%), Positives = 268/694 (38%), Gaps = 131/694 (18%)
Query: 135 QEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAK 194
+E + L T EE L+++HC L +Q I L+ ++ IST Q +EA
Sbjct: 1466 KEIVAKHLET-EEELKVAHC-------CLKEQEETINELRVNLSEKETEISTIQKQLEA- 1516
Query: 195 ANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTR 254
DK LQ+ IQ + E+ F ++ +++++ +E+ KE +
Sbjct: 1517 -------INDK-------LQNKIQEIY-EKEEQFNIKQISEVQEKVNELKQFKEHRKAKD 1561
Query: 255 SELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKE 314
S L++ E L+L +R +E ++E ++ +KE +E
Sbjct: 1562 SALQSI------------------ESKMLELTNRLQESQEEI---------QIMIKEKEE 1594
Query: 315 LTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKW 374
+ AL+ + +++++ +I + +K++ E KE F + + ++QE
Sbjct: 1595 MKRVQEALQIERDQLKENTKEI---VAKMKESQE-KE------YQFLKMTAVNETQEKM- 1643
Query: 375 TARVQAIHQEHKKEKGRLLS-HIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELII 433
++ + ++ + +K L + E +R + I N + + + + L+ E +
Sbjct: 1644 -CEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEM---RSVTKERDDLRSVEETLK 1699
Query: 434 TQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHE 493
+R Q+K+ + LE + L +VH
Sbjct: 1700 VERDQLKE-------------------------------NLRETITRDLEKQEELKIVHM 1728
Query: 494 QAFSSHILEPIEELSEEEKGRENE-QKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEK 552
E I++L + NE + + H ALK+ + + +L E+
Sbjct: 1729 HLKEHQ--ETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQ 1786
Query: 553 LETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEKALL 612
ET+ I +D+L + K +E+ K + +I Q + EHQ+ I K +
Sbjct: 1787 QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI----QELKANEHQL---ITLKKDV 1839
Query: 613 SSDQCSVSQMD-----------TLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKK 661
+ Q VS+M+ TLS E+ + + L K+V +R ++ ++++
Sbjct: 1840 NETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEE 1899
Query: 662 NVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSDA 721
+ + K S T E +QE + ++K + K K
Sbjct: 1900 TLKLERDQLKESLQETKARDLEIQQE----------LKTARMLSKEHKETVDKLREKISE 1949
Query: 722 DGTEGSEIE-DTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQ 780
+ S+I+ D D S ++ +K ++ +++VN N E K+ E Q
Sbjct: 1950 KTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQ 2009
Query: 781 ELKCADVEDEDWDIS-SLEEEISLGKKSGKEQKE 813
L V +++ ++ L E + + KE+ E
Sbjct: 2010 NLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDE 2043
Score = 47.8 bits (112), Expect = 4e-05
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 38/313 (12%)
Query: 131 LLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLM 190
L HS + L +Q ++E LR++H ++ ++ + K G + ++ +K +
Sbjct: 1758 LEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLEN---- 1813
Query: 191 IEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNA-QIEKLRSEIVVLKEE 249
+ A LQ IQ E+ +K+ + +K SE+ LK++
Sbjct: 1814 ------------------SNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1855
Query: 250 LQ---LTRSELEAAHHASAVRFSKEYEMQKT--KEEDFLKLFDRWKEEEKEKLVDEMEKV 304
++ LT S+LE + A + + E K+ KE D L+ + + E+++L + +++
Sbjct: 1856 IKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQET 1915
Query: 305 KEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVM 364
K ++ +EL + + + K +I + D ++D + +
Sbjct: 1916 KARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD---IQKDLDKSKDELQKKI 1972
Query: 365 QLLDSQESKWTARVQAIHQEHKK--EKGRLLSHIEKLRTSM----IDDLNASNVFYKKRI 418
Q L +E + + ++ HKK E +L E SM +D+ + ++ +
Sbjct: 1973 QELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHES-L 2031
Query: 419 EELGQRLQEQNEL 431
EE+ +E++EL
Sbjct: 2032 EEIRIVAKERDEL 2044
Score = 43.1 bits (100), Expect = 0.001
Identities = 132/687 (19%), Positives = 264/687 (38%), Gaps = 112/687 (16%)
Query: 213 LQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVL------KEELQLTRSELEAAHHASAV 266
LQ I H E+ ++ ++ ++ +E+ +L K+ L R E+E
Sbjct: 1278 LQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKF 1337
Query: 267 RFSKEYEMQKTKEEDFLKLFDRWKE----EEKEKLVDEMEKVKEMFMKEFKELTSKNSAL 322
+ S+E TKE D LK E + KE + + + K++E K+ + L K
Sbjct: 1338 QESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDN 1397
Query: 323 EYQ--LSEIQ----KSNMQIKSNI------GTLKDAHEFKEDRSPYPQDFHNVMQLLDSQ 370
E +SE++ K + ++ I L+++H+ + + D + ++L S+
Sbjct: 1398 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSE 1457
Query: 371 ESKWTARVQAIHQEHKKEKGRL-LSH---------IEKLRTSMID-DLNASNVFYKKRIE 419
+ ++ I +H + + L ++H I +LR ++ + + S + +K++E
Sbjct: 1458 SDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI--QKQLE 1515
Query: 420 ELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPAL 479
+ +LQ + + I + +Q + ISE + + F+ A + +
Sbjct: 1516 AINDKLQNKIQEIYEKEEQFN------IKQISEVQEKVNELKQFKEHRKAKDSALQSIES 1569
Query: 480 HTLETKSSLPMVHEQAFSSHILEPIEELS--EEEKGRENEQKLNNNKMHLRKALKSN--- 534
LE + L E+ +++ EE+ +E E +Q N K + K +S
Sbjct: 1570 KMLELTNRLQESQEEI--QIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKE 1627
Query: 535 ------SSLTKGLRTMVE-QNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQERE 587
+++ + M E ++L E+ ET +N + + +L ++L E +E
Sbjct: 1628 YQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKE 1687
Query: 588 IPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQK 647
+ + E L K+E L + + ++++ L E K++ + K Q K
Sbjct: 1688 RDDLRSVEETL------KVERDQLKENLRETITR--DLEKQEELKIVHMHLKEHQETIDK 1739
Query: 648 ---AVSTDRTSVPKIKKNVMEDPFPRKSSTITTPP------FSSEEEQEDDDLIRAYASP 698
VS + ++K++ K+ + +E+QE D +R S
Sbjct: 1740 LRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSE 1799
Query: 699 GPLPVPPPQN--KGSFGK---------------NTVKSDADGTEG--SEIEDTDDSPKPA 739
+ Q + S K T+K D + T+ SE+E K
Sbjct: 1800 KTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQ 1859
Query: 740 GVAVK-------TPTEKVEKMFPHRKNVNKPVGGTNVPEMFIK------KEELQELKCAD 786
+ + +K+ + K+V K E +K KE LQE K D
Sbjct: 1860 SLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARD 1919
Query: 787 VEDEDWDISSLEEEISLGKKSGKEQKE 813
+E +++E+ + KE KE
Sbjct: 1920 LE--------IQQELKTARMLSKEHKE 1938
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 53.9 bits (128), Expect = 6e-07
Identities = 73/320 (22%), Positives = 142/320 (44%), Gaps = 36/320 (11%)
Query: 126 FTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMIS 185
F I+ LL S E + EE E++K+ L K + K L+E+ + +
Sbjct: 838 FKIKPLLKSAETEKEMANMKEEF--------EKTKEELAKTEAKRKELEEKMVTLMQEKN 889
Query: 186 TQQLMIEAKANYYQC--HFCDKAFMNQAFLQSHIQR--RHTEENSHFEYQKNAQIEKLRS 241
QL ++A+A+ CD+ + L++ I+ E+ + A+ KL
Sbjct: 890 DLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLED 949
Query: 242 EIVVLK---EELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWK--EEEKEK 296
E LK ++L+LT +++E HA+ + E +E KL K +E ++
Sbjct: 950 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Query: 297 LVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPY 356
+D+++ ++ + LT + LE Q+ +++ S Q K L+ A E
Sbjct: 1010 TLDDLQMEED----KVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKL 1065
Query: 357 PQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKK 416
Q+ +D++ K Q ++++ KK++ + S+++ I+D A + +K
Sbjct: 1066 AQE-----STMDTENDK-----QQLNEKLKKKEFEM-SNLQ----GKIEDEQALAIQLQK 1110
Query: 417 RIEELGQRLQEQNELIITQR 436
+I+EL R++E E I +R
Sbjct: 1111 KIKELQARIEELEEEIEAER 1130
Score = 44.7 bits (104), Expect = 4e-04
Identities = 108/563 (19%), Positives = 217/563 (38%), Gaps = 95/563 (16%)
Query: 157 EQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFM-------N 209
E+ + L Q EIKT +EE +R +S Q+ + ++ + +K M
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGK 1309
Query: 210 QAFLQ--SHIQRRHTEE---------------------NSHFEYQKNAQIE--------- 237
QAF Q ++R+ EE +E ++ A+ E
Sbjct: 1310 QAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKAN 1369
Query: 238 --------KLRSEIVVLKEELQLTRSEL-----EAAHHASAVRFSKEYEMQKTKEEDFLK 284
K ++ + EEL+ + +L +A H AV SK ++KTK+ +
Sbjct: 1370 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN-SKCASLEKTKQRLQNE 1428
Query: 285 LFDRWKEEEKEKLV-DEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTL 343
+ D + E+ ++K + F K E K + +L QK + + + + +
Sbjct: 1429 VEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKV 1488
Query: 344 KDAHEFKEDR-SPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTS 402
K+A+E D ++ N+ Q + + + IH+ K +K L H + +
Sbjct: 1489 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK--QLDHEKSELQT 1546
Query: 403 MIDDLNASNVFYKKRI----EELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPL 458
+++ AS + +I EL Q E + I + +++ N L + E + L
Sbjct: 1547 SLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLR-VVESMQSTL 1605
Query: 459 AWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQ 518
+ A L+ +E + + H ++ L + R +
Sbjct: 1606 DAEIRSRNDALRIKKKMEGDLNEME----IQLNHANRQAAEALRNL---------RNTQG 1652
Query: 519 KLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVE 578
L + ++HL A++ + +L E+L + A++ ++L L+ E
Sbjct: 1653 ILKDTQLHLDDAIRG------------QDDLKEQLAMVERRANLMQAEVEELRASLERTE 1700
Query: 579 SERHKQEREIPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPS 638
R E+E+ + + + L Q + I K L +D +SQ+ GE+ ++Q +
Sbjct: 1701 RGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD---ISQIQ----GEMEDIVQ-EA 1752
Query: 639 KNRQLIRQKAVSTDRTSVPKIKK 661
+N + +KA++ ++KK
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELKK 1775
Score = 40.8 bits (94), Expect = 0.005
Identities = 87/490 (17%), Positives = 195/490 (39%), Gaps = 55/490 (11%)
Query: 139 TSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYY 198
T +L +++L D E+ + + + ++ K+ + + LMI+ + +
Sbjct: 1387 TEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNE-----VEDLMIDVERSNA 1441
Query: 199 QCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELE 258
C DK N + + ++++ E + E + + L +E+ +K + + LE
Sbjct: 1442 ACIALDKKQRNFDKVLAEWKQKYEETQAELEASQK-ESRSLSTELFKVKNAYEESLDHLE 1500
Query: 259 AAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSK 318
+ K +++ L ++ E K + E+EKVK+ E EL +
Sbjct: 1501 TLKREN-----------KNLQQEISDLTEQIAEGGKH--IHELEKVKKQLDHEKSELQTS 1547
Query: 319 NSALEYQLSEIQKSNMQIKSNIGTLKDAHEFK--EDRSPYPQDFHNVMQLLDSQESKWTA 376
E L + ++I+ + +K + K E Q N +++++S +S A
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDA 1607
Query: 377 RVQAIHQE---HKKEKGRL------LSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQE 427
+++ + KK +G L L+H + + +L + K L ++
Sbjct: 1608 EIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRG 1667
Query: 428 QNEL-----IITQRQQIKDFTCNPLNSISE--PKGNPLAWQAFESQPAAPAVPMNAPALH 480
Q++L ++ +R + L + E +G +A Q E A+ V + LH
Sbjct: 1668 QDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQ--ELLDASERVQL----LH 1721
Query: 481 TLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENE-QKLNNNKMHLRKALKSNSSLTK 539
T T + S I +E++ +E + E + +K + + + LK +
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 540 GLRTMVEQNLMEKLETLGINAD------IRGISS--DQLHRVLKSVESERHKQEREIPNF 591
L M ++N+ + ++ L + D ++G +L ++ +ESE +++ N
Sbjct: 1782 HLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKH--NV 1838
Query: 592 HQIREFLEHQ 601
++ +H+
Sbjct: 1839 EAVKGLRKHE 1848
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.5 bits (127), Expect = 8e-07
Identities = 67/323 (20%), Positives = 148/323 (45%), Gaps = 43/323 (13%)
Query: 128 IEYLLHSQEFLTSQLHT---LEERLRLSHCDGEQSKKLLTKQAGEI----KTLKEECKRR 180
IE L ++ L+ +L+ +E L+ + + ++ +L+ + EI K LK + +R
Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 181 KKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKL- 239
+ ++ QQL +EA D+ + + +Q + EEN + Q EK+
Sbjct: 252 QLLLPQQQLQVEA----------DRLGKELQSVSAKLQAQ-VEENELWNLLNQQQEEKMW 300
Query: 240 RSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDR-WKEEEKEKLV 298
R E + ++E ++ EL+ + ++ E +EE + D+ W++E EK+
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEE--KMWRQEEKMHEQEEKIREQEDKMWRQE--EKIR 356
Query: 299 DEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQ 358
++ EK++E K +++ + Q +IQ+ ++ +++ E ++++
Sbjct: 357 EQEEKIREQEEKMWRQ----EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK----- 407
Query: 359 DFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRI 418
+ QE K + + I +E ++E R I +L M+ D ++++
Sbjct: 408 --------MWRQEKKMREQDEKI-REQEEEMWRQEEKIRELE-EMMQDQEEKLREVEEKM 457
Query: 419 EELGQRLQEQNELIITQRQQIKD 441
+E +++QEQ E I Q ++I++
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQE 480
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/302 (17%), Positives = 132/302 (43%), Gaps = 11/302 (3%)
Query: 138 LTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEE-CKRRKKMISTQQLMIEAKAN 196
++++L E L + +Q ++ + +Q +I+ +E+ C++ K+ ++ M +
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 197 YYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSE 256
++ + ++ + Q R E+ E + Q EK+R + ++E+ + +
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393
Query: 257 LEAAHHASAVRFSKEYEMQKTKEEDFLKLFDR----WKEEEKEKLVDEMEKVKEMFMKEF 312
E R K + +K E K+ ++ W++EEK + ++EM + +E ++E
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453
Query: 313 KE-LTSKNSALEYQLSEIQKSNMQI-KSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQ 370
+E + + ++ Q +IQ+ +I + T + K++ + Q+ ++ +
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE----EKMWRQE 509
Query: 371 ESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNE 430
E W + QE K ++ +++R ++ + +EE +L ++ E
Sbjct: 510 EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Query: 431 LI 432
L+
Sbjct: 570 LL 571
Score = 31.6 bits (70), Expect = 3.3
Identities = 29/178 (16%), Positives = 79/178 (44%), Gaps = 5/178 (2%)
Query: 267 RFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQL 326
+F + EM+ E + RW E++ + ++ ++ KE + L + + +
Sbjct: 62 KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121
Query: 327 SEIQKSNMQIKSNIGTLKDAHEFK----EDRSPYPQDFHNVMQLLDSQESKWTARVQAIH 382
S ++K++ ++KS+ ++ K R + + + ++ + + + + +H
Sbjct: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLH 181
Query: 383 QEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIK 440
+H G + + K R ++ +L N + ++E LQE+ L+ +++ +I+
Sbjct: 182 FDHAVRMGTYIEKLTKERDALSLEL-YRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
Length = 1079
Score = 53.5 bits (127), Expect = 8e-07
Identities = 63/318 (19%), Positives = 142/318 (44%), Gaps = 41/318 (12%)
Query: 145 LEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRR-----KKMISTQQLMIEAKANYYQ 199
LE+ +R + ++ L KQ EI +LK+E K+ K ++ Q M E N
Sbjct: 185 LEQNVREAIQSNKRLSALNKKQEAEICSLKKELKKAASDLIKSKVTCQYKMGEENINLTI 244
Query: 200 CHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEA 259
+ + ++ + + EE +H + +K I + +L++++Q +E+EA
Sbjct: 245 KEQKFQELQERLNMELELNEKINEEITHIQEEKQDIIISFQHMQQLLRQQIQ-ANTEMEA 303
Query: 260 AHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKN 319
++ KE ++ + + + EE+ L +E EK + + +EL +
Sbjct: 304 -----ELKVLKENNQTLERDNELQREKVKENEEKFLNLQNEHEKALGTWKRHAEELNGEI 358
Query: 320 SALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTAR-- 377
+ ++ +LS +++++++++ + L + F+ED+ F NV ++ + T +
Sbjct: 359 NKIKNELSSLKETHIKLQEHYNKLCNQKTFEEDKK-----FQNVPEVNNENSEMSTEKSE 413
Query: 378 ---------VQAIHQEH-----------KKEKGRLLSHIEKLRTSMIDDLNASNVFYKKR 417
Q I +E+ +KE+ + S IE++ +IDDL +K
Sbjct: 414 NTIIQKYNTEQEIREENMENFCSDTEYREKEEKKEGSFIEEI---IIDDLQLFEKSFKNE 470
Query: 418 IEELGQRLQEQNELIITQ 435
I+ + + + Q+E+ +++
Sbjct: 471 IDTVVSQDENQSEISLSK 488
Score = 51.6 bits (122), Expect = 3e-06
Identities = 82/330 (24%), Positives = 137/330 (41%), Gaps = 44/330 (13%)
Query: 219 RRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKT- 277
R E H+E Q I + + E+ KE LQ + L H + F K+ +M+
Sbjct: 42 RMRREAEIHYEEQIGKIIVETQ-ELKWQKETLQNQKETLAEQHKEAMAVFKKQLQMKMCA 100
Query: 278 --KEEDFLKLFDRWKEEEKEKLVDEME-----------KVKEMFMKEFKELTSKNSALEY 324
+E+ +L KE+E E L + ++ KV EM K L +K
Sbjct: 101 LEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKVQLHLLAKED-YHK 159
Query: 325 QLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQ---LLDSQESKWTARVQAI 381
QLSEI+K I G +K+ HE E Q+ +Q L + K A + ++
Sbjct: 160 QLSEIEKYYATITGQFGLVKENHEKLE------QNVREAIQSNKRLSALNKKQEAEICSL 213
Query: 382 HQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKD 441
+E KK L+ + M ++ N + +++ +EL +RL + EL ++I +
Sbjct: 214 KKELKKAASDLIKSKVTCQYKMGEE-NINLTIKEQKFQELQERLNMELEL----NEKINE 268
Query: 442 FTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHIL 501
+ I E K + + Q + N E ++ L ++ E ++ L
Sbjct: 269 ----EITHIQEEKQDIIISFQHMQQLLRQQIQANT------EMEAELKVLKE---NNQTL 315
Query: 502 EPIEELSEEEKGRENEQKLNNNKMHLRKAL 531
E EL + EK +ENE+K N + KAL
Sbjct: 316 ERDNEL-QREKVKENEEKFLNLQNEHEKAL 344
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 53.1 bits (126), Expect = 1e-06
Identities = 93/465 (20%), Positives = 182/465 (39%), Gaps = 45/465 (9%)
Query: 145 LEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCD 204
LE + + SKK L A ++ L+E KR +K I E KA Y D
Sbjct: 1362 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY-----D 1416
Query: 205 KAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHAS 264
K + LQ + + ++ + N + +K R +L EE ++ + A
Sbjct: 1417 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLE-KKQRKFDQLLAEEKNISSKYADERDRAE 1475
Query: 265 AVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEY 324
A KE TK + EE + +E+E+ +M E ++L S +
Sbjct: 1476 AEAREKE-----TKALSLARAL-----EEALEAKEELERTNKMLKAEMEDLVSSKDDVGK 1525
Query: 325 QLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQL-LDSQESKWTARVQAIHQ 383
+ E++KS +++ + +K E ED +D +++ + + + ++ +QA +
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 384 EHKKEKGRLLSHIEKLRTSMIDD--LNASNVFYKKRIEELGQRLQEQNELIITQRQ---- 437
++++++ +L + + T + D+ A KK++E + L+ Q + I R+
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 438 -------QIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPM 490
Q+KDF + + + + A + A + A + E ++
Sbjct: 1646 QLRKLQAQMKDFQ----RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 491 VHEQAFSSHILEPIEELSEEEKGR----ENEQKLNNNKMHLRKALKSNSSLTKGL----- 541
+QA E EEL+ GR + +++L L + L+ + +
Sbjct: 1702 ARKQA-DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
Query: 542 -RTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQE 585
T + L +L T A + QL R K + S+ H+ E
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 1805
Score = 52.0 bits (123), Expect = 2e-06
Identities = 99/517 (19%), Positives = 208/517 (40%), Gaps = 48/517 (9%)
Query: 208 MNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVR 267
+ Q Q ++ +E E + A+ E++R + K+EL+ E+EA R
Sbjct: 878 LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDR 937
Query: 268 FSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKV-KEMFMKEFKE-----------L 315
+ +K + L L ++ +EEE + ++EKV E +K+ ++ L
Sbjct: 938 GQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKL 997
Query: 316 TSKNSALEYQLSEIQKS---NMQIKSNIGTLKDAHEF----------KEDRSPYPQDFHN 362
+ + LE ++S++ + + N+ LK+ HE KE++S Q+
Sbjct: 998 SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS--RQELEK 1055
Query: 363 VMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSM--IDDLNASNVFYKKRIEE 420
+ + L+ S + ++ + + + K +L E+L+ ++ +DD A K+I E
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 421 LGQRLQEQNELIITQR------QQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPM 474
L + + E + ++R ++ K L ++ + L A + + A
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQE 1175
Query: 475 NAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEE-EKGRENEQKLNNNKMHLRKALKS 533
L+ ++ Q + +EEL+E+ E+ + + L+ NK L K
Sbjct: 1176 VTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE---KE 1232
Query: 534 NSSLTKGLRTMVEQNLMEKLETLGINADIRGISS--DQLHRVLKSVESERHKQEREIPNF 591
N+ L LR + + + + + A ++ + S R + + HK + E+ +
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 592 HQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVST 651
+ E + ++ A LSS + L E + + + +K RQL ++
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSS---QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 652 DRTSVPKIKKNVMEDPFPRKSSTITTPPFSSEEEQED 688
D+ K +E R ST+ S+++ +D
Sbjct: 1350 DQLDEEMEAKQNLE----RHISTLNIQLSDSKKKLQD 1382
Score = 50.1 bits (118), Expect = 9e-06
Identities = 105/505 (20%), Positives = 203/505 (40%), Gaps = 53/505 (10%)
Query: 131 LLHSQEFLTSQLHTLEERLRLSHCDGEQ---SKKLLTKQAGEIKTLKEECKRRKKMISTQ 187
L ++ L LH +E RL G+Q +K + +Q +++ EE + ++ + +
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 972
Query: 188 QLMIEAKANYYQCHFC------DKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRS 241
++ EAK + +K + L+ I T E KN K +
Sbjct: 973 KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 242 EIVVLKEELQLTRSE--------LEAAHHASAVRFSK----------EYEMQKTKEEDFL 283
E ++ + E++L + E L+ A F + E +MQ K+E+ L
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Query: 284 KLFDRWKEEEKEKLVDEMEKVKEM--FMKEFKE-LTSKNSA---LEYQLSEIQKSNMQIK 337
+ ++E + + ++K++E+ + + +E L S+ +A E Q ++ + +K
Sbjct: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK 1152
Query: 338 SNI-GTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHI 396
+ + TL +E R+ Q+ + + LD + A+VQ + Q+H + L +
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1212
Query: 397 EKLRTSMID------DLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSI 450
E+ + + + L N + LGQ QE Q+++ S
Sbjct: 1213 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK--CSD 1270
Query: 451 SEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEE 510
E L + + Q +V L+ E K ++ + + A S L+ +EL +E
Sbjct: 1271 GERARAELNDKVHKLQNEVESV---TGMLNEAEGK-AIKLAKDVASLSSQLQDTQELLQE 1326
Query: 511 EKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVE--QNLMEKLETLGINADIRGISSD 568
E QKLN + LR+ + +SL L +E QNL + TL I
Sbjct: 1327 ----ETRQKLNVS-TKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ 1381
Query: 569 QLHRVLKSVESERHKQEREIPNFHQ 593
++++E + + ++EI N Q
Sbjct: 1382 DFASTVEALEEGKKRFQKEIENLTQ 1406
Score = 45.1 bits (105), Expect = 3e-04
Identities = 107/523 (20%), Positives = 196/523 (37%), Gaps = 78/523 (14%)
Query: 117 LLKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEE 176
L+ + Q + LL ++ ++S+ +R + E L + E KEE
Sbjct: 1442 LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Query: 177 CKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQI 236
+R KM+ KA M ++ E + Q+
Sbjct: 1502 LERTNKML--------------------KAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 237 EKLRSEIVVLKEELQLT---RSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEE 293
E++++++ L++ELQ T + LE A +F ++ + + + E+ + R E
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 294 KEKLVDEMEK------VKEMFMKEFKEL-TSKNSAL---EYQLSEIQKSNMQIKSNIGTL 343
+ +L DE ++ K+ + K+L +SA+ E + +++K Q+K L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 344 KDAH--------EFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSH 395
+DA KE+ ++MQL + + AR QA K+E L+
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA--DLEKEELAEELAS 1719
Query: 396 IEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKG 455
R ++ D+ + RI +L + L+E+ + +++ T +E
Sbjct: 1720 SLSGRNALQDEKRR----LEARIAQLEEELEEEQGNMEAMSDRVRKAT-----QQAEQLS 1770
Query: 456 NPLAWQAFESQPAAPAVPMNAPALHTLE--TKSSLPMVHE------QAFSSHILEPIEEL 507
N LA + +Q N A LE K +HE F S I ++
Sbjct: 1771 NELATERSTAQ-------KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Query: 508 SEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISS 567
++ E+ E E + K K+LK K + VE + E A+
Sbjct: 1824 AQLEEQVEQEAR---EKQAATKSLKQKDKKLKEILLQVEDE-RKMAEQYKEQAEKGNARV 1879
Query: 568 DQLHRVLKSVESE-------RHKQEREIPNFHQIREFLEHQVS 603
QL R L+ E E R K +RE+ + E + +V+
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1922
Score = 43.1 bits (100), Expect = 0.001
Identities = 68/335 (20%), Positives = 135/335 (40%), Gaps = 35/335 (10%)
Query: 290 KEEEKEKLVDEMEKVKEMFMK---EFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDA 346
+EEE + DE++K KE K E KEL K+S L + + +Q+ Q+++ +A
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE---QLQAETELYAEA 906
Query: 347 HEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKL--RTSMI 404
E + + Q+ ++ ++++ + R Q + E KK ++L E+L +
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 405 DDLNASNVFYKKRIEELGQR---LQEQNELIITQR----QQIKDFTCNPLNSISEPKGNP 457
L V + +I++L + +QN + +R ++I D T N + K
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 458 LAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENE 517
ES + LE + + ++ S LE ++ E + +E
Sbjct: 1027 KLKNKHESM------------ISELEVR-----LKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 518 Q--KLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLK 575
Q L L+ L + ++ + +K L ++ G SD L L
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD-LQEDLD 1128
Query: 576 SVESERHKQEREIPNFHQIREFLEHQVSCKIEEKA 610
S + R+K E++ + + E L+ ++ ++ A
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTA 1163
Score = 39.3 bits (90), Expect = 0.016
Identities = 55/201 (27%), Positives = 92/201 (45%), Gaps = 37/201 (18%)
Query: 246 LKEELQLTRSELEAAHHASAVRFSKEYEMQKTKE-----EDFLKLFDRWKE---EEKEKL 297
+K LQ+TR E E +KE E+QKTKE E+ LK ++ EEK L
Sbjct: 841 VKPLLQVTRQEEEMQ--------AKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892
Query: 298 VDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYP 357
++++ E++ E +E+ + +A + +L EI + ++ E +EDR
Sbjct: 893 QEQLQAETELY-AEAEEMRVRLAAKKQELEEI----------LHEMEARLEEEEDRGQQL 941
Query: 358 QDFHNVM--QLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMI--DD----LNA 409
Q M Q+LD +E +A Q+ + EK + I+KL ++ DD L+
Sbjct: 942 QAERKKMAQQMLDLEEQ--LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK 999
Query: 410 SNVFYKKRIEELGQRLQEQNE 430
++RI +L L E+ E
Sbjct: 1000 ERKLLEERISDLTTNLAEEEE 1020
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,938,016
Number of Sequences: 37866
Number of extensions: 1806169
Number of successful extensions: 16764
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 1160
Number of HSP's that attempted gapping in prelim test: 11291
Number of HSP's gapped (non-prelim): 5649
length of query: 867
length of database: 18,247,518
effective HSP length: 111
effective length of query: 756
effective length of database: 14,044,392
effective search space: 10617560352
effective search space used: 10617560352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.