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Search of human proteins with 38787991
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38787991 transmembrane 4 superfamily member 8 isoform 2
[Homo sapiens]
(228 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo... 474 e-134
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ... 460 e-130
gi|21265104 tetraspanin 7 [Homo sapiens] 99 3e-21
gi|87159824 CD151 antigen [Homo sapiens] 96 3e-20
gi|87159822 CD151 antigen [Homo sapiens] 96 3e-20
gi|21237751 CD151 antigen [Homo sapiens] 96 3e-20
gi|21237748 CD151 antigen [Homo sapiens] 96 3e-20
gi|67782354 CD82 antigen isoform 2 [Homo sapiens] 94 1e-19
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens] 93 2e-19
gi|68800005 tetraspanin 4 isoform a [Homo sapiens] 82 3e-16
gi|4507543 tetraspanin 4 isoform a [Homo sapiens] 82 3e-16
gi|68800018 tetraspanin 4 isoform a [Homo sapiens] 82 3e-16
gi|68800024 tetraspanin 4 isoform a [Homo sapiens] 82 3e-16
gi|68800011 tetraspanin 4 isoform a [Homo sapiens] 82 3e-16
gi|68799997 tetraspanin 4 isoform a [Homo sapiens] 82 3e-16
gi|4504813 CD82 antigen isoform 1 [Homo sapiens] 80 1e-15
gi|4502679 CD63 antigen isoform A [Homo sapiens] 78 5e-15
gi|5729941 tetraspanin 9 [Homo sapiens] 75 6e-14
gi|91199546 CD63 antigen isoform B [Homo sapiens] 72 4e-13
gi|122937466 tetraspanin 11 [Homo sapiens] 70 1e-12
gi|10834972 CD53 antigen [Homo sapiens] 68 7e-12
gi|91106727 CD53 antigen [Homo sapiens] 68 7e-12
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens] 66 2e-11
gi|21264578 tetraspan 1 [Homo sapiens] 66 3e-11
gi|30425534 tetraspanin 33 [Homo sapiens] 66 3e-11
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens] 63 2e-10
gi|68800032 tetraspanin 4 isoform b [Homo sapiens] 63 2e-10
gi|4502663 CD37 antigen isoform A [Homo sapiens] 61 7e-10
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens] 59 4e-09
gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens] 57 1e-08
>gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo
sapiens]
Length = 228
Score = 474 bits (1220), Expect = e-134
Identities = 228/228 (100%), Positives = 228/228 (100%)
Query: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV
Sbjct: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
Query: 61 GALLFIIGLIGCCATIRESRCGLATVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQL 120
GALLFIIGLIGCCATIRESRCGLATVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQL
Sbjct: 61 GALLFIIGLIGCCATIRESRCGLATVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQL 120
Query: 121 HCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKL 180
HCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKL
Sbjct: 121 HCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKL 180
Query: 181 QEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA 228
QEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA
Sbjct: 181 QEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA 228
>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
sapiens]
Length = 253
Score = 460 bits (1184), Expect = e-130
Identities = 228/253 (90%), Positives = 228/253 (90%), Gaps = 25/253 (9%)
Query: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV
Sbjct: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
Query: 61 GALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQ 95
GALLFIIGLIGCCATIRESRCGLAT VENEVDRSIQ
Sbjct: 61 GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
Query: 96 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 155
KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS
Sbjct: 121 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 180
Query: 156 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 215
NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD
Sbjct: 181 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240
Query: 216 PAYELLITGGTYA 228
PAYELLITGGTYA
Sbjct: 241 PAYELLITGGTYA 253
>gi|21265104 tetraspanin 7 [Homo sapiens]
Length = 249
Score = 99.0 bits (245), Expect = 3e-21
Identities = 72/231 (31%), Positives = 103/231 (44%), Gaps = 37/231 (16%)
Query: 6 ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65
IT KT+L+ + +FW IL VG + +T Y + T P V+I G +
Sbjct: 12 ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIV 70
Query: 66 IIGLIGCCATIRESRCGLA---------------------TVENEVDRSIQKVY----KT 100
+ GL GC AT R S L +E+ + + Y +T
Sbjct: 71 VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
Query: 101 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 160
YNG D SRA+D+VQR L CCG+ NY++W + +F E +P SCC ++CN
Sbjct: 131 YNGN--DERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLE---HGIPPSCCM-NETDCNPQ 184
Query: 161 LAHPSDLYA-----EGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 206
H + A +GC LV ++ M + A A QL+GML AC
Sbjct: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235
>gi|87159824 CD151 antigen [Homo sapiens]
Length = 253
Score = 95.5 bits (236), Expect = 3e-20
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 31/233 (13%)
Query: 4 CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
CG K +L N FW A + VG + DY L A +++ G +
Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70
Query: 64 LFIIGLIGCCATIRESR-------------------CGLAT------VENEVDRSIQKVY 98
+ + G++GCCAT +E R G+ + E+ +++
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 99 -KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 155
K Y+ +A + A+D +Q++ HCCG +N DW +++W + E + VP SCC+ +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190
Query: 156 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 206
C G H S++Y GC + +QE + + + A +Q+ GM+ C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242
>gi|87159822 CD151 antigen [Homo sapiens]
Length = 253
Score = 95.5 bits (236), Expect = 3e-20
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 31/233 (13%)
Query: 4 CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
CG K +L N FW A + VG + DY L A +++ G +
Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70
Query: 64 LFIIGLIGCCATIRESR-------------------CGLAT------VENEVDRSIQKVY 98
+ + G++GCCAT +E R G+ + E+ +++
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 99 -KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 155
K Y+ +A + A+D +Q++ HCCG +N DW +++W + E + VP SCC+ +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190
Query: 156 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 206
C G H S++Y GC + +QE + + + A +Q+ GM+ C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242
>gi|21237751 CD151 antigen [Homo sapiens]
Length = 253
Score = 95.5 bits (236), Expect = 3e-20
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 31/233 (13%)
Query: 4 CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
CG K +L N FW A + VG + DY L A +++ G +
Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70
Query: 64 LFIIGLIGCCATIRESR-------------------CGLAT------VENEVDRSIQKVY 98
+ + G++GCCAT +E R G+ + E+ +++
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 99 -KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 155
K Y+ +A + A+D +Q++ HCCG +N DW +++W + E + VP SCC+ +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190
Query: 156 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 206
C G H S++Y GC + +QE + + + A +Q+ GM+ C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242
>gi|21237748 CD151 antigen [Homo sapiens]
Length = 253
Score = 95.5 bits (236), Expect = 3e-20
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 31/233 (13%)
Query: 4 CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
CG K +L N FW A + VG + DY L A +++ G +
Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70
Query: 64 LFIIGLIGCCATIRESR-------------------CGLAT------VENEVDRSIQKVY 98
+ + G++GCCAT +E R G+ + E+ +++
Sbjct: 71 VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130
Query: 99 -KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 155
K Y+ +A + A+D +Q++ HCCG +N DW +++W + E + VP SCC+ +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190
Query: 156 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 206
C G H S++Y GC + +QE + + + A +Q+ GM+ C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242
>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
Length = 242
Score = 93.6 bits (231), Expect = 1e-19
Identities = 66/238 (27%), Positives = 104/238 (43%), Gaps = 22/238 (9%)
Query: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP--AVVII 58
MG I +K L NLIF+ ++ G ++ + + + + A V I
Sbjct: 1 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 60
Query: 59 AVGALLFIIGLIGCCATIRESRCGLATVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQR 118
VGA+ ++G +GC + E RC L ++ E+ + ++ + YN + D+ A DYVQ
Sbjct: 61 GVGAVTMLMGFLGCIGAVNEVRCLLGLLKQEMGGIVTELIRDYNSSREDSLQDAWDYVQA 120
Query: 119 QLHCCGIHNYSDWENTDWFKETKNQSVPLSC----------------CRETASNCNGSLA 162
Q+ CCG ++ +W + + P SC C E N S
Sbjct: 121 QVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFC-EAPGNRTQSGN 179
Query: 163 HPSD--LYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAY 218
HP D +Y EGC V LQE + ++ + A I+LLGM+ + I LCR Y
Sbjct: 180 HPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLS-ICLCRHVHSEDY 236
>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
Length = 245
Score = 93.2 bits (230), Expect = 2e-19
Identities = 68/241 (28%), Positives = 107/241 (44%), Gaps = 34/241 (14%)
Query: 6 ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65
IT K+VL+ IFW IL VG + ++ ++Y + T +P V+IA G ++
Sbjct: 14 ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP-FVLIATGTVII 72
Query: 66 IIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQKVYKT 100
++G GC AT R S L ++N + +K K
Sbjct: 73 LLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQ 132
Query: 101 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 160
YN T D S A+D +Q LHCCG+ +Y DW +T+++ E + P SCC+ +C
Sbjct: 133 YNSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE---KGFPKSCCK--LEDCTPQ 186
Query: 161 LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYEL 220
+ EGC V+ ++ M V + A QL+G+ A L R + YE+
Sbjct: 187 -RDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA-YCLSRAITNNQYEI 244
Query: 221 L 221
+
Sbjct: 245 V 245
>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 3e-16
Identities = 62/244 (25%), Positives = 100/244 (40%), Gaps = 34/244 (13%)
Query: 1 MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
M + + + K ++ NL+FW G G+L VG ++ T + +L A ++I
Sbjct: 1 MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59
Query: 60 VGALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSI 94
GA + IG +GC I+E++C L T ++ + +
Sbjct: 60 TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119
Query: 95 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 154
+K Y + A +Q CCG+ NY TDWF+ VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174
Query: 155 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
+C L P + C V LQE ++ V L A +Q+LG+ A + C+ +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232
Query: 215 DPAY 218
Y
Sbjct: 233 ADTY 236
>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 3e-16
Identities = 62/244 (25%), Positives = 100/244 (40%), Gaps = 34/244 (13%)
Query: 1 MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
M + + + K ++ NL+FW G G+L VG ++ T + +L A ++I
Sbjct: 1 MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59
Query: 60 VGALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSI 94
GA + IG +GC I+E++C L T ++ + +
Sbjct: 60 TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119
Query: 95 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 154
+K Y + A +Q CCG+ NY TDWF+ VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174
Query: 155 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
+C L P + C V LQE ++ V L A +Q+LG+ A + C+ +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232
Query: 215 DPAY 218
Y
Sbjct: 233 ADTY 236
>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 3e-16
Identities = 62/244 (25%), Positives = 100/244 (40%), Gaps = 34/244 (13%)
Query: 1 MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
M + + + K ++ NL+FW G G+L VG ++ T + +L A ++I
Sbjct: 1 MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59
Query: 60 VGALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSI 94
GA + IG +GC I+E++C L T ++ + +
Sbjct: 60 TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119
Query: 95 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 154
+K Y + A +Q CCG+ NY TDWF+ VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174
Query: 155 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
+C L P + C V LQE ++ V L A +Q+LG+ A + C+ +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232
Query: 215 DPAY 218
Y
Sbjct: 233 ADTY 236
>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 3e-16
Identities = 62/244 (25%), Positives = 100/244 (40%), Gaps = 34/244 (13%)
Query: 1 MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
M + + + K ++ NL+FW G G+L VG ++ T + +L A ++I
Sbjct: 1 MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59
Query: 60 VGALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSI 94
GA + IG +GC I+E++C L T ++ + +
Sbjct: 60 TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119
Query: 95 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 154
+K Y + A +Q CCG+ NY TDWF+ VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174
Query: 155 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
+C L P + C V LQE ++ V L A +Q+LG+ A + C+ +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232
Query: 215 DPAY 218
Y
Sbjct: 233 ADTY 236
>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 3e-16
Identities = 62/244 (25%), Positives = 100/244 (40%), Gaps = 34/244 (13%)
Query: 1 MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
M + + + K ++ NL+FW G G+L VG ++ T + +L A ++I
Sbjct: 1 MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59
Query: 60 VGALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSI 94
GA + IG +GC I+E++C L T ++ + +
Sbjct: 60 TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119
Query: 95 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 154
+K Y + A +Q CCG+ NY TDWF+ VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174
Query: 155 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
+C L P + C V LQE ++ V L A +Q+LG+ A + C+ +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232
Query: 215 DPAY 218
Y
Sbjct: 233 ADTY 236
>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 3e-16
Identities = 62/244 (25%), Positives = 100/244 (40%), Gaps = 34/244 (13%)
Query: 1 MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
M + + + K ++ NL+FW G G+L VG ++ T + +L A ++I
Sbjct: 1 MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59
Query: 60 VGALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSI 94
GA + IG +GC I+E++C L T ++ + +
Sbjct: 60 TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119
Query: 95 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 154
+K Y + A +Q CCG+ NY TDWF+ VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174
Query: 155 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
+C L P + C V LQE ++ V L A +Q+LG+ A + C+ +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232
Query: 215 DPAY 218
Y
Sbjct: 233 ADTY 236
>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
Length = 267
Score = 80.5 bits (197), Expect = 1e-15
Identities = 65/263 (24%), Positives = 104/263 (39%), Gaps = 47/263 (17%)
Query: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP--AVVII 58
MG I +K L NLIF+ ++ G ++ + + + + A V I
Sbjct: 1 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 60
Query: 59 AVGALLFIIGLIGCCATIRESRC-------------------------GLATVENEVDRS 93
VGA+ ++G +GC + E RC + ++ E+
Sbjct: 61 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI 120
Query: 94 IQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSC---- 149
+ ++ + YN + D+ A DYVQ Q+ CCG ++ +W + + P SC
Sbjct: 121 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 180
Query: 150 ------------CRETASNCNGSLAHPSD--LYAEGCEALVVKKLQEIMMHVIWAALAFA 195
C E N S HP D +Y EGC V LQE + ++ + A
Sbjct: 181 EEDNSLSVRKGFC-EAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVA 239
Query: 196 AIQLLGMLCACIVLCRRSRDPAY 218
I+LLGM+ + I LCR Y
Sbjct: 240 IIELLGMVLS-ICLCRHVHSEDY 261
>gi|4502679 CD63 antigen isoform A [Homo sapiens]
Length = 238
Score = 78.2 bits (191), Expect = 5e-15
Identities = 55/197 (27%), Positives = 93/197 (47%), Gaps = 34/197 (17%)
Query: 50 TLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLAT------------------------ 85
+L+P VVIIAVG LF++ +GCC +E+ C + T
Sbjct: 51 SLLP-VVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRD 109
Query: 86 -VENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS 144
V +E + + ++ + Y N A+ +D +Q CCG NY+DWE + +
Sbjct: 110 KVMSEFNNNFRQQMENYPKNNHTAS--ILDRMQADFKCCGAANYTDWEKIPSMSKNR--- 164
Query: 145 VPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC 204
VP SCC C G + ++ EGC + L++ ++ V AAL A +++LG++
Sbjct: 165 VPDSCCINVTVGC-GINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVF 223
Query: 205 ACIVLCRRSRDPAYELL 221
AC ++ +S YE++
Sbjct: 224 ACCLV--KSIRSGYEVM 238
>gi|5729941 tetraspanin 9 [Homo sapiens]
Length = 239
Score = 74.7 bits (182), Expect = 6e-14
Identities = 52/219 (23%), Positives = 93/219 (42%), Gaps = 34/219 (15%)
Query: 10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69
K ++ NLIFW L VG ++ ++ ++ F +L A ++IA+G ++ + G
Sbjct: 10 KYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGF 69
Query: 70 IGCCATIRESRCGLAT-------------------------VENEVDRSIQKVYKTYNGT 104
+GC I+E++C L + V + +++ Y+
Sbjct: 70 LGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHTE 129
Query: 105 NPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHP 164
N A + +Q ++ CCG+ +Y TDW+ +VP CC E + C + P
Sbjct: 130 NNVGLKNAWNIIQAEMRCCGVTDY-----TDWYPVLGENTVPDRCCMENSQGCGRNATTP 184
Query: 165 SDLYAEGCEALVVKKLQEIMMHVI-WAALAFAAIQLLGM 202
L+ GC VK + HV+ + +Q+LGM
Sbjct: 185 --LWRTGCYE-KVKMWFDDNKHVLGTVGMCILIMQILGM 220
>gi|91199546 CD63 antigen isoform B [Homo sapiens]
Length = 236
Score = 72.0 bits (175), Expect = 4e-13
Identities = 55/197 (27%), Positives = 91/197 (46%), Gaps = 36/197 (18%)
Query: 50 TLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLAT------------------------ 85
+L+P VVIIAVG LF++ +GCC +E+ C + T
Sbjct: 51 SLLP-VVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRD 109
Query: 86 -VENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS 144
V +E + + ++ + Y N A+ +D +Q CCG NY+DWE + +
Sbjct: 110 KVMSEFNNNFRQQMENYPKNNHTAS--ILDRMQADFKCCGAANYTDWEKIPSMSKNR--- 164
Query: 145 VPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC 204
VP SCC C G + ++ EGC + L++ ++ V AAL A + LG++
Sbjct: 165 VPDSCCINVTVGC-GINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVF 221
Query: 205 ACIVLCRRSRDPAYELL 221
AC ++ +S YE++
Sbjct: 222 ACCLV--KSIRSGYEVM 236
>gi|122937466 tetraspanin 11 [Homo sapiens]
Length = 253
Score = 70.5 bits (171), Expect = 1e-12
Identities = 50/235 (21%), Positives = 98/235 (41%), Gaps = 31/235 (13%)
Query: 10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69
K +L N FW + VG + + Y A ++I G L+ + G
Sbjct: 17 KYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGF 76
Query: 70 IGCCATIRESRCGLAT-------------------------VENEVDRSIQKVY-KTYNG 103
+G A + E + L+T + +E+ + + + + Y
Sbjct: 77 LGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQ 136
Query: 104 TNPDAASRAIDYVQRQLHCCGIHNYSDWENTDW--FKETKNQSVPLSCCRETASNCNGSL 161
+ ++D +Q+ CCG ++ +DW+++ + +E + + VP SCC+ C G
Sbjct: 137 PGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRC-GQR 195
Query: 162 AHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 214
AHPS++Y GC + + L + ++ + + A +Q+ GM+ C + R R
Sbjct: 196 AHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQR 250
>gi|10834972 CD53 antigen [Homo sapiens]
Length = 219
Score = 67.8 bits (164), Expect = 7e-12
Identities = 55/236 (23%), Positives = 92/236 (38%), Gaps = 52/236 (22%)
Query: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
MG + K VL F NL+FW + G Y+ I ++++ F ++ +L V + V
Sbjct: 1 MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLI-HNNFGVLFHNLPSLTLGNVFVIV 59
Query: 61 GALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQ 95
G+++ ++ +GC +I+E++C L + + V + +
Sbjct: 60 GSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLT 119
Query: 96 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 155
Y+ N A A D +Q L CCGI+ SDW P SC
Sbjct: 120 DSIHRYHSDNSTKA--AWDSIQSFLQCCGINGTSDW----------TSGPPASC------ 161
Query: 156 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCR 211
PSD EGC A +++ + I++LGM A + C+
Sbjct: 162 --------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQ 209
>gi|91106727 CD53 antigen [Homo sapiens]
Length = 219
Score = 67.8 bits (164), Expect = 7e-12
Identities = 55/236 (23%), Positives = 92/236 (38%), Gaps = 52/236 (22%)
Query: 1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
MG + K VL F NL+FW + G Y+ I ++++ F ++ +L V + V
Sbjct: 1 MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLI-HNNFGVLFHNLPSLTLGNVFVIV 59
Query: 61 GALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQ 95
G+++ ++ +GC +I+E++C L + + V + +
Sbjct: 60 GSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLT 119
Query: 96 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 155
Y+ N A A D +Q L CCGI+ SDW P SC
Sbjct: 120 DSIHRYHSDNSTKA--AWDSIQSFLQCCGINGTSDW----------TSGPPASC------ 161
Query: 156 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCR 211
PSD EGC A +++ + I++LGM A + C+
Sbjct: 162 --------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQ 209
>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
Length = 237
Score = 66.2 bits (160), Expect = 2e-11
Identities = 56/227 (24%), Positives = 101/227 (44%), Gaps = 41/227 (18%)
Query: 17 NLIFWGAAGILCYVGAYVFITYDDYDHF-FEDV--YTLIPAVVIIAVGALLFIIGLIGCC 73
N +FW ++ + +V ++ D F EDV + + ++IAVGA++ I+G +GCC
Sbjct: 16 NFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGFLGCC 75
Query: 74 ATIRESRCGL---------------------ATVENEVDRSI-QKVYK-----TYNGTNP 106
I+ESRC L A +++ DR + + +Y+ + G +
Sbjct: 76 GAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENTKLLSATGESE 135
Query: 107 DAASRAIDYVQRQLHCCGIHN-YSDWENTDWFKETKNQSVPLSC-CRETASNCNGSLAHP 164
AI Q + CCG+ N +DW N Q P C C + C +
Sbjct: 136 KQFQEAIIVFQEEFKCCGLVNGAADWGN-------NFQHYPELCACLDKQRPCQS--YNG 186
Query: 165 SDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCR 211
+Y E C + + L + ++ VI + A I++LG++ + ++ C+
Sbjct: 187 KQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQ 233
>gi|21264578 tetraspan 1 [Homo sapiens]
Length = 241
Score = 65.9 bits (159), Expect = 3e-11
Identities = 55/236 (23%), Positives = 96/236 (40%), Gaps = 40/236 (16%)
Query: 10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVV-----IIAVGALL 64
KT+++ NL+ + L VG +V I + F + + V +IA G ++
Sbjct: 8 KTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVV 67
Query: 65 FIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQKVYK 99
F +G +GC ES+C L T E+ + + K
Sbjct: 68 FALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIK 127
Query: 100 TYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASN--- 156
G+ D ++ + + L CCG NY+D+E++ +FKE N + P CC + +N
Sbjct: 128 KDYGSQEDF-TQVWNTTMKGLKCCGFTNYTDFEDSPYFKE--NSAFPPFCCNDNVTNTAN 184
Query: 157 --CNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLC 210
C AH D EGC ++ ++ + V A ++L M+ + + C
Sbjct: 185 ETCTKQKAH--DQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYC 238
>gi|30425534 tetraspanin 33 [Homo sapiens]
Length = 283
Score = 65.9 bits (159), Expect = 3e-11
Identities = 58/241 (24%), Positives = 99/241 (41%), Gaps = 43/241 (17%)
Query: 10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69
K +L F N++FW + ++ VG Y + + + PA+++I VG L+F++
Sbjct: 23 KYLLFFFNMLFWVISMVMVAVGVYARLM--KHAEAALACLAVDPAILLIVVGVLMFLLTF 80
Query: 70 IGCCATIRESRCGLATVENEV------------------DRSIQKVYKTYNGT-----NP 106
GC ++RE+ C L T + D++ KV + N +
Sbjct: 81 CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140
Query: 107 DAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQ------SVPLSCCRETASN---- 156
ID+ Q++ CCG +Y DW +F +++ SVP SCC T
Sbjct: 141 LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200
Query: 157 --CNGS------LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIV 208
C L +Y GC +V + + + AL A QL+G+L + I+
Sbjct: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQIL 260
Query: 209 L 209
+
Sbjct: 261 V 261
>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
Length = 248
Score = 63.2 bits (152), Expect = 2e-10
Identities = 56/239 (23%), Positives = 99/239 (41%), Gaps = 36/239 (15%)
Query: 2 GQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFE-DVYTLIPAVVIIAV 60
G C + VF IF G A +L +G +V + + + L A +++A+
Sbjct: 3 GDCLSCMKYLMFVFNFFIFLGGACLLA-IGIWVMVDPTGFREIVAANPLLLTGAYILLAM 61
Query: 61 GALLFIIGLIGCCATIRESRCGL----------------ATVENEVDRS-------IQKV 97
G LLF++G +GCC +RE++C L A + + R +++
Sbjct: 62 GGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKEL 121
Query: 98 YKTYNGTN-PDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETA 154
K Y G N D S + V CCG++ D++ F+ ++ VP +CCR
Sbjct: 122 TKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREP 181
Query: 155 SNCNGSLAHPSD--------LYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCA 205
+ +G L + L +GC +++ + + A+ AI+L M+ A
Sbjct: 182 QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFA 240
>gi|68800032 tetraspanin 4 isoform b [Homo sapiens]
Length = 174
Score = 62.8 bits (151), Expect = 2e-10
Identities = 48/177 (27%), Positives = 71/177 (40%), Gaps = 32/177 (18%)
Query: 67 IGLIGCCATIRESRCGLATV---------------------ENEVDRSIQKVYKT----Y 101
IG +GC I+E++C L T +++DR Q+ K Y
Sbjct: 3 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 62
Query: 102 NGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSL 161
+ A +Q CCG+ NY TDWF+ VP SCC E + +C L
Sbjct: 63 GTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFSESC--GL 115
Query: 162 AHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAY 218
P + C V LQE ++ V L A +Q+LG+ A + C+ + Y
Sbjct: 116 HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTY 172
>gi|4502663 CD37 antigen isoform A [Homo sapiens]
Length = 281
Score = 61.2 bits (147), Expect = 7e-10
Identities = 66/258 (25%), Positives = 104/258 (40%), Gaps = 57/258 (22%)
Query: 10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP--AVVIIAVGALLFII 67
K L NL F+ ++ G ++ I + F + + + V+ G I
Sbjct: 12 KYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGI 71
Query: 68 GLIGCCATIRESRCGL---------------------ATVENEVDRSIQKVY-KTYN--G 103
L+GC ++E RC L +T +++RS++ V KT G
Sbjct: 72 ALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYG 131
Query: 104 TNPD--AASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS--VPLSCCRETASNCN- 158
TNP+ AA + DYVQ QL CCG H DW + +++ VP SC +A+N +
Sbjct: 132 TNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDST 191
Query: 159 -------------GSLA---HPSD---------LYAEGCEALVVKKLQEIMMHVIWAALA 193
G LA H +D +Y EGC + K L ++ ++ L
Sbjct: 192 ILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLG 251
Query: 194 FAAIQLLGMLCACIVLCR 211
++ LG + I LCR
Sbjct: 252 VGLLE-LGFMTLSIFLCR 268
>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
Length = 267
Score = 58.5 bits (140), Expect = 4e-09
Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 36/232 (15%)
Query: 2 GQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFE-DVYTLIPAVVIIAV 60
G C + VF IF G A +L +G +V + + + L A +++A+
Sbjct: 3 GDCLSCMKYLMFVFNFFIFLGGACLLA-IGIWVMVDPTGFREIVAANPLLLTGAYILLAM 61
Query: 61 GALLFIIGLIGCCATIRESRCGL----------------ATVENEVDRS-------IQKV 97
G LLF++G +GCC +RE++C L A + + R +++
Sbjct: 62 GGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKEL 121
Query: 98 YKTYNGTN-PDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETA 154
K Y G N D S + V CCG++ D++ F+ ++ VP +CCR
Sbjct: 122 TKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREP 181
Query: 155 SNCNGSLAHPSD--------LYAEGCEALVVKKLQEIMMHVIWAALAFAAIQ 198
+ +G L + L +GC +++ + + A+ AI+
Sbjct: 182 QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233
>gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]
Length = 245
Score = 57.4 bits (137), Expect = 1e-08
Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 4/110 (3%)
Query: 93 SIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRE 152
+++K Y+ YN PD S + V +L CCG++NY+D+ + F+ T + P SCC+
Sbjct: 126 TLRKNYRGYN--EPDDYSTQWNLVMEKLKCCGVNNYTDFSGSS-FEMTTGHTYPRSCCKS 182
Query: 153 TAS-NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLG 201
S +C+G P+ ++ +GC ++K + + ++L A IQ G
Sbjct: 183 IGSVSCDGRDVSPNVIHQKGCFHKLLKITKTQSFTLSGSSLGAAVIQRWG 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,375,001
Number of Sequences: 37866
Number of extensions: 333414
Number of successful extensions: 1237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1110
Number of HSP's gapped (non-prelim): 71
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.