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Search of human proteins with 38679890
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38679890 solute carrier organic anion transporter family,
member 4C1 [Homo sapiens]
(724 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38679890 solute carrier organic anion transporter family, mem... 1469 0.0
gi|93277099 solute carrier organic anion transporter family, mem... 525 e-149
gi|39777594 solute carrier organic anion transporter family memb... 510 e-144
gi|225637473 solute carrier organic anion transporter family, me... 394 e-109
gi|222831575 solute carrier organic anion transporter family, me... 358 1e-98
gi|222831573 solute carrier organic anion transporter family, me... 358 1e-98
gi|225543525 solute carrier organic anion transporter family, me... 341 1e-93
gi|9790233 solute carrier organic anion transporter family, memb... 337 3e-92
gi|225637477 solute carrier organic anion transporter family, me... 331 1e-90
gi|225637475 solute carrier organic anion transporter family, me... 331 1e-90
gi|8394291 solute carrier organic anion transporter family, memb... 325 1e-88
gi|188528663 solute carrier organic anion transporter family, me... 318 8e-87
gi|225543118 solute carrier organic anion transporter family, me... 317 2e-86
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 303 4e-82
gi|223634012 solute carrier organic anion transporter family, me... 297 2e-80
gi|6005820 solute carrier organic anion transporter family, memb... 297 2e-80
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 292 7e-79
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 292 7e-79
gi|225543116 solute carrier organic anion transporter family, me... 288 9e-78
gi|225543114 solute carrier organic anion transporter family, me... 276 4e-74
gi|223634014 solute carrier organic anion transporter family, me... 238 1e-62
gi|194239645 spinster homolog 3 [Homo sapiens] 39 0.017
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 36 0.11
gi|116517292 cut-like 2 [Homo sapiens] 36 0.14
gi|110349719 titin isoform N2-A [Homo sapiens] 35 0.19
gi|110349717 titin isoform novex-2 [Homo sapiens] 35 0.19
gi|110349713 titin isoform novex-1 [Homo sapiens] 35 0.19
gi|110349715 titin isoform N2-B [Homo sapiens] 35 0.19
gi|150170670 piccolo isoform 2 [Homo sapiens] 35 0.24
gi|150378539 piccolo isoform 1 [Homo sapiens] 35 0.24
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 1469 bits (3804), Expect = 0.0
Identities = 724/724 (100%), Positives = 724/724 (100%)
Query: 1 MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPE 60
MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPE
Sbjct: 1 MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPE 60
Query: 61 PSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPGGFLLHYCLLAVTQGI 120
PSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPGGFLLHYCLLAVTQGI
Sbjct: 61 PSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPGGFLLHYCLLAVTQGI 120
Query: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF
Sbjct: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
Query: 181 MIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLG 240
MIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLG
Sbjct: 181 MIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLG 240
Query: 241 AGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGES 300
AGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGES
Sbjct: 241 AGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGES 300
Query: 301 TDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNA 360
TDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNA
Sbjct: 301 TDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNA 360
Query: 361 DVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
DVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA
Sbjct: 361 DVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
Query: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP
Sbjct: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
Query: 481 FAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPK 540
FAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPK
Sbjct: 481 FAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPK 540
Query: 541 VYYNCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITV 600
VYYNCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITV
Sbjct: 541 VYYNCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITV 600
Query: 601 SILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYD 660
SILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYD
Sbjct: 601 SILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYD 660
Query: 661 NIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQDLNKI 720
NIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQDLNKI
Sbjct: 661 NIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQDLNKI 720
Query: 721 VKEG 724
VKEG
Sbjct: 721 VKEG 724
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 525 bits (1353), Expect = e-149
Identities = 263/598 (43%), Positives = 375/598 (62%), Gaps = 6/598 (1%)
Query: 97 CLQRCNTPGGFLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFC 156
C + CN F++ YC+L + QG+V GL+++SI +K Y++K+ + SYDIS
Sbjct: 98 CCECCNNIRCFMIFYCILLICQGVVF-GLIDVSIGDFQKEYQLKTIEKLALEKSYDISSG 156
Query: 157 LLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNST 216
L+++F++F+G+R K W ++F+IGLG+L+ + P + ED C + +
Sbjct: 157 LVAIFIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVS 215
Query: 217 SCTSSTSSL-SNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSI 275
C SS S S YL FILGQ + G G PLY LG F+D++V TH + +Y+G S+
Sbjct: 216 GCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSM 275
Query: 276 LGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCF 335
+G A+GYVLG L+ + + +T V P WL WWI FL + + AW +IP SCF
Sbjct: 276 IGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCF 335
Query: 336 PKHLPGTAEIQAGKTSQAHQSNSNA-DVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSE 394
P ++PG+ I+A K Q H +S D+K G +IKD AAL LMKN V +CL LS ++E
Sbjct: 336 PNNMPGSTRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICLALSKATE 395
Query: 395 ALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTM 454
L+ G + FLP ++ENQF LT + A TL G VLIPG ALGQ+LGG +VS M+CK M
Sbjct: 396 YLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALM 455
Query: 455 KFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYP 514
+F + TS ++L L ++ +C FAG++E Y+GTG+LGNL APCN C CS S Y
Sbjct: 456 RFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSS 515
Query: 515 VCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETH 573
+CG D ++YFSPCFAGC+ A + K+YYNCSCI ++ IT+ AE +A+ GKC+
Sbjct: 516 ICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCI-KEGLITADAEGDFIDARPGKCDAK 574
Query: 574 CAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPII 633
C KLP+F+ F +IF+ +G PI +++ R V + RSLALG+ +++LR+ GTIPGP I
Sbjct: 575 CYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSI 634
Query: 634 FGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYK 691
F + +++CIL D+N CG G CWIY+ KMA +LV I CK+ T+ F A F+YK
Sbjct: 635 FKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYK 692
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 510 bits (1313), Expect = e-144
Identities = 272/624 (43%), Positives = 378/624 (60%), Gaps = 27/624 (4%)
Query: 89 GWRNFHPQCLQRCNTPGGFLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLIS 148
GW F P CLQ NTP G L C A QG+ VNG +N I+++E+RY++ S +GLI+
Sbjct: 87 GWWAFAPPCLQVLNTPKGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLIA 146
Query: 149 SSYDISFCLLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDT 208
SSYDI+ CL FVS+FG GHKPRWL + ++G G+LVF+LP F +G Y++
Sbjct: 147 SSYDIAACLCLTFVSYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVR 206
Query: 209 CVTTRNSTSCTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
C STS LS Y VF+LGQ L G G TPLYTLG +LD++V + S +YI
Sbjct: 207 TCPANPGAVCADSTSGLSRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIA 266
Query: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328
Y +ILGPA GY++GG LL IY + MG T++T + P W+GAWW+GFL S A+
Sbjct: 267 IFYTAAILGPAAGYLIGGALLNIYTE--MGRRTELTTESPLWVGAWWVGFLGSGAAAFFT 324
Query: 329 IIPFSCFPKHLPGTAEIQAGKTSQAHQSNSN-----ADVKFGKSIKDFPAALKNLMKNAV 383
+P +P+ LPG+ + ++ HQ + ++ FGK+I+D P ++ L+KN
Sbjct: 325 AVPILGYPRQLPGSQRYAVMRAAEMHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPT 384
Query: 384 FMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLV 443
F+ L L+ ++EA + TG +TF PKF+E+QF L++S AATL G +++P G LGGF V
Sbjct: 385 FILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFV 444
Query: 444 SKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGT----GELGNLIA 499
+K R+ +KF LF + V+L L + C + P AGV+ SY G+ G L NL A
Sbjct: 445 NKLRLRGSAVIKFCLFCTVVSL-LGILVFSLHCPSVPMAGVTASYGGSLLPEGHL-NLTA 502
Query: 500 PCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRK----PKVYYNCSCIERKTEI 554
PCNA C+C +Y PVCG DG+ YFS C AGC P A KVY +CSCI +
Sbjct: 503 PCNAACSCQPEHYSPVCGSDGLMYFSLCHAGC--PAATETNVDGQKVYRDCSCIPQ---- 556
Query: 555 TSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLA 614
+ + FG A AGKC + C + P+ L F+VI FTF++ P + LRCV QRS A
Sbjct: 557 -NLSSGFG-HATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFA 614
Query: 615 LGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVT 674
LGIQ++V+R+LG IPGPI FG+ ID C+LW + CG +G+C +Y N M+ ++ + +
Sbjct: 615 LGIQWIVVRILGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNSAMSRYILIMGLL 673
Query: 675 CKVITMFFNGFAIFLYKPPPSATD 698
KV+ + F A FLYKP ++D
Sbjct: 674 YKVLGVLFFAIACFLYKPLSESSD 697
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 394 bits (1013), Expect = e-109
Identities = 238/692 (34%), Positives = 358/692 (51%), Gaps = 55/692 (7%)
Query: 42 ENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRC 101
++S QEL++ P +P PS PS + + R F S +CL
Sbjct: 65 DSSGHQELKQGPNPL-APSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVV 123
Query: 102 NTPGG-FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSL 160
T FL+ C L Q ++V+G ++ I+T+E+RY +KSS +GL+ S +DI ++ +
Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183
Query: 161 FVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLF----EDTCVTTRNST 216
FVS+FG RG +P WLA +I GA +F+LP F S Y++ L D NST
Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNST 243
Query: 217 S------CTSSTSSLSNYLYV--FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
+ C + ++++YV FI Q+L+G G TP+YTLG +LDD+V SSLY+
Sbjct: 244 ATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLA 303
Query: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328
Y M LGPA+GY+LGG L+ Y+D D ++DPR++G WW GFLL I + +
Sbjct: 304 IMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLD--QNDPRFIGNWWSGFLLCAIAMFLV 361
Query: 329 IIPFSCFPKHLP----------------GTAEIQAGKTSQAHQSNSN-ADVKFGKSIKDF 371
I P FPK LP ++ K++ + Q++ + + FGK ++D
Sbjct: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDL 421
Query: 372 PAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPG 431
P A ++ N F+ + LS ++E+ I T F TF+PKFIE+QFG+ +S A+ G +++P
Sbjct: 422 PRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPS 481
Query: 432 AALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGT 491
A +G +LGG+++ K ++ + + K A+ SGV+L CE+ G++ Y
Sbjct: 482 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 541
Query: 492 GEL----GNLIAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNP-VAHRKPKVYYNC 545
L NL CN NC C Y PVCG DG+ YF+PC AGC N + Y C
Sbjct: 542 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC 601
Query: 546 SCIERKTEITS------------TAETFGFE---AKAGKCETHCAKLPIFLCIFFIVIIF 590
+C++ + IT +T+ E A +GKC+ C L FL FIV
Sbjct: 602 TCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFI 661
Query: 591 TFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDC 650
T A + LR V +R ALG+QF++LR L IP PI FG ID+TC+LW +C
Sbjct: 662 TACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QEC 720
Query: 651 GIKGACWIYDNIKMAHMLVAISVTCKVITMFF 682
G++G+CW Y+ + ++ K + F
Sbjct: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIF 752
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 358 bits (919), Expect = 1e-98
Identities = 217/626 (34%), Positives = 332/626 (53%), Gaps = 68/626 (10%)
Query: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
FL+ C L + QG V LV++ ++T+E+R+ ++S+ G+I+SS++I L LFVS+FG
Sbjct: 42 FLVSECALMLAQGTVGAYLVSV-LTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFG 100
Query: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL-------GSLFEDTCVTTRNSTS-- 217
RGH+PR + ++ LGAL+ +LP+F + +YK G+ D C +
Sbjct: 101 ARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEG 160
Query: 218 ------CTSSTSSLSNYLYVFILG-QLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTG 270
C + T++ N +Y+ ++G Q+LLG G TP+ LG +++DD V SSLYIG
Sbjct: 161 PDPDLICRNRTAT--NMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGIL 218
Query: 271 YAMSILGPAIGYVLGGQLLTIYIDVAMGEST--DVTEDDPRWLGAWWIGFLLSWIFAWSL 328
+ M + GPA G++LG IY+D +++ D+T DDPRW+GAWW GFLL +
Sbjct: 219 FTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFS 278
Query: 329 IIPFSCFPKHLPGTAEIQAGKTSQA------------------HQSNSNADVKFGKSIKD 370
+ FP+ LP +E A ++ QA H ++ + ++
Sbjct: 279 SLLMFGFPQSLPPHSE-PAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRV 337
Query: 371 FPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIP 430
P K+L+ N VF C++L+ E + GFA FL K++E QF LT+S A L G IP
Sbjct: 338 IPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIP 397
Query: 431 GAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNG 490
A LG LGG LV K ++ ++ A+ + V+ F++ C+ P AGV+ Y
Sbjct: 398 CACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGN 457
Query: 491 TGELGNLI---APCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCS 546
+ G+ + +PCN NC C + PVCG DG+ Y S CFAGC++ C+
Sbjct: 458 STAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNS-------TNLTGCA 510
Query: 547 CIERKTEITSTAETFGFEAKAGKCET-HCAKLPI-FLCIFFIVIIFTFMAGTPITVSILR 604
C+ +T GKC + C + + FLC+ I + MA TP + ++R
Sbjct: 511 CL-------TTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIR 563
Query: 605 CVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKM 664
V+ +S ALG+ F++LRLLG IP P+IFG IDSTC+ W CG +GAC +YDN+
Sbjct: 564 TVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVY 622
Query: 665 AHMLVAISVTCKVITMFFNGFAIFLY 690
++ V+I++ K FA LY
Sbjct: 623 RYLYVSIAIALK-------SFAFILY 641
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 358 bits (919), Expect = 1e-98
Identities = 217/626 (34%), Positives = 332/626 (53%), Gaps = 68/626 (10%)
Query: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
FL+ C L + QG V LV++ ++T+E+R+ ++S+ G+I+SS++I L LFVS+FG
Sbjct: 42 FLVSECALMLAQGTVGAYLVSV-LTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFG 100
Query: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL-------GSLFEDTCVTTRNSTS-- 217
RGH+PR + ++ LGAL+ +LP+F + +YK G+ D C +
Sbjct: 101 ARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEG 160
Query: 218 ------CTSSTSSLSNYLYVFILG-QLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTG 270
C + T++ N +Y+ ++G Q+LLG G TP+ LG +++DD V SSLYIG
Sbjct: 161 PDPDLICRNRTAT--NMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGIL 218
Query: 271 YAMSILGPAIGYVLGGQLLTIYIDVAMGEST--DVTEDDPRWLGAWWIGFLLSWIFAWSL 328
+ M + GPA G++LG IY+D +++ D+T DDPRW+GAWW GFLL +
Sbjct: 219 FTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFS 278
Query: 329 IIPFSCFPKHLPGTAEIQAGKTSQA------------------HQSNSNADVKFGKSIKD 370
+ FP+ LP +E A ++ QA H ++ + ++
Sbjct: 279 SLLMFGFPQSLPPHSE-PAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRV 337
Query: 371 FPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIP 430
P K+L+ N VF C++L+ E + GFA FL K++E QF LT+S A L G IP
Sbjct: 338 IPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIP 397
Query: 431 GAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNG 490
A LG LGG LV K ++ ++ A+ + V+ F++ C+ P AGV+ Y
Sbjct: 398 CACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGN 457
Query: 491 TGELGNLI---APCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCS 546
+ G+ + +PCN NC C + PVCG DG+ Y S CFAGC++ C+
Sbjct: 458 STAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNS-------TNLTGCA 510
Query: 547 CIERKTEITSTAETFGFEAKAGKCET-HCAKLPI-FLCIFFIVIIFTFMAGTPITVSILR 604
C+ +T GKC + C + + FLC+ I + MA TP + ++R
Sbjct: 511 CL-------TTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIR 563
Query: 605 CVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKM 664
V+ +S ALG+ F++LRLLG IP P+IFG IDSTC+ W CG +GAC +YDN+
Sbjct: 564 TVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVY 622
Query: 665 AHMLVAISVTCKVITMFFNGFAIFLY 690
++ V+I++ K FA LY
Sbjct: 623 RYLYVSIAIALK-------SFAFILY 641
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 341 bits (875), Expect = 1e-93
Identities = 204/663 (30%), Positives = 344/663 (51%), Gaps = 55/663 (8%)
Query: 101 CNTPGGFL--LHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLL 158
CN FL L +A T G ++ + SI +E+R+E+ SSL G I S++I L+
Sbjct: 24 CNGLKMFLAALSLSFIAKTLGAII---MKSSIIHIERRFEISSSLVGFIDGSFEIGNLLV 80
Query: 159 SLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSC 218
+FVS+FG + H+P+ + F++G+G ++ +LP FF G Y+ E ++ NSTS
Sbjct: 81 IVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSK--ETNINSSENSTST 138
Query: 219 TSST---------------------SSLSNYLYVFI-LGQLLLGAGGTPLYTLGTAFLDD 256
S+ +Y+++++ +G +L G G TP+ LG +++DD
Sbjct: 139 LSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDD 198
Query: 257 SVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDV--TEDDPRWLGAW 314
SSLY+G A++++GP IG+ LG +Y+D+ + + + T D RW+GAW
Sbjct: 199 FAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAW 258
Query: 315 WIGFLLSWIFAWSLIIPFSCFP-------KHLPGTAEIQAGKTSQAHQSNSNADVK---F 364
W+ FL+S +F+ IPF P K + + +T+ +N +
Sbjct: 259 WLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNI 318
Query: 365 GKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLG 424
K++ F + K+++ N +++ VL T + G T++ K++E Q+G SS A L
Sbjct: 319 TKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILL 378
Query: 425 GAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGV 484
G + IP A G LGG+++ KF++ KF+ FT+ ++L+ ++ + CEN+ AG+
Sbjct: 379 GVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGL 438
Query: 485 SESYNG----TGELGNLIAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKP 539
+ +Y+G T ++ CN++CNC S + PVCG +G+ Y SPC AGC + ++KP
Sbjct: 439 TMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKP 498
Query: 540 KVYYNCSCIERKTEITSTAETFGFEAKAGKCETHCA---KLPIFLCIFFIVIIFTFMAGT 596
V+YNCSC+E + + + A G+C A K F+ I + + F+ + GT
Sbjct: 499 IVFYNCSCLE-----VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGT 553
Query: 597 PITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGAC 656
+ I++ V +SLALG MV+R LG I PI FG ID+TCI W N+CG +G+C
Sbjct: 554 SHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSC 613
Query: 657 WIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQD 716
Y++ + + + +S +V ++ I+ K D++ EN V + +
Sbjct: 614 RTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDIN-ASENGSVMDEANLES 672
Query: 717 LNK 719
LNK
Sbjct: 673 LNK 675
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 337 bits (863), Expect = 3e-92
Identities = 200/639 (31%), Positives = 332/639 (51%), Gaps = 58/639 (9%)
Query: 99 QRCNTPGGFL--LHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFC 156
+RCN FL L + +A G ++ + ISI+ +E+R+++ SSL GLI S++I
Sbjct: 22 RRCNGFKMFLAALSFSYIAKALGGII---MKISITQIERRFDISSSLAGLIDGSFEIGNL 78
Query: 157 LLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNST 216
L+ +FVS+FG + H+P+ + ++G G+++ SLP FF G Y+ E + NST
Sbjct: 79 LVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSK--ETHINPSENST 136
Query: 217 SCTSST-----------------------SSLSNYLYVFILGQLLLGAGGTPLYTLGTAF 253
S S+ S ++YVF +G +L G G TP+ LG ++
Sbjct: 137 SSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVF-MGNMLRGIGETPIVPLGISY 195
Query: 254 LDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDV--TEDDPRWL 311
+DD SSLY+G+ A+ ++GP IG+ LG +Y+D+ + + + T D RW+
Sbjct: 196 IDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWV 255
Query: 312 GAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNAD---------- 361
GAWW+GFL+S +F+ IPF PK+ P + + + H +N D
Sbjct: 256 GAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKISLSLHVLKTNDDRNQTANLTNQ 314
Query: 362 -VKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
K++ F +LK+++ N +++ +L T + G T++ K++E Q+G ++S A
Sbjct: 315 GKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHA 374
Query: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
L G + IP A G LGGF++ KF+++ KF+ TS ++ ++ CE++
Sbjct: 375 NFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKS 434
Query: 481 FAGVSESYNGTGELGNLI----APCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVA 535
AG++ +Y+G + + + + CN+ CNC S + PVCG +G+ Y SPC AGC +
Sbjct: 435 VAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSG 494
Query: 536 HRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKC---ETHCAKLPIFLCIFFIVIIFTF 592
+K V+YNCSC+E + + + A G+C T K I++ I I +F+
Sbjct: 495 IKKHTVFYNCSCVE-----VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSA 549
Query: 593 MAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGI 652
GT + ++ V ++LA+G Q MV+R LG I PI FG ID TC+ W N CG
Sbjct: 550 TGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGA 609
Query: 653 KGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYK 691
+GAC IY+++ + + +S+ + + IF K
Sbjct: 610 QGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMK 648
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 331 bits (849), Expect = 1e-90
Identities = 206/604 (34%), Positives = 310/604 (51%), Gaps = 54/604 (8%)
Query: 42 ENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRC 101
++S QEL++ P +P PS PS + + R F S +CL
Sbjct: 65 DSSGHQELKQGPNPL-APSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVV 123
Query: 102 NTPGG-FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSL 160
T FL+ C L Q ++V+G ++ I+T+E+RY +KSS +GL+ S +DI ++ +
Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183
Query: 161 FVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLF----EDTCVTTRNST 216
FVS+FG RG +P WLA +I GA +F+LP F S Y++ L D NST
Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNST 243
Query: 217 S------CTSSTSSLSNYLYV--FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
+ C + ++++YV FI Q+L+G G TP+YTLG +LDD+V SSLY+
Sbjct: 244 ATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLA 303
Query: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328
Y M LGPA+GY+LGG L+ Y+D D ++DPR++G WW GFLL I + +
Sbjct: 304 IMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLD--QNDPRFIGNWWSGFLLCAIAMFLV 361
Query: 329 IIPFSCFPKHLP----------------GTAEIQAGKTSQAHQSNSN-ADVKFGKSIKDF 371
I P FPK LP ++ K++ + Q++ + + FGK ++D
Sbjct: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDL 421
Query: 372 PAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPG 431
P A ++ N F+ + LS ++E+ I T F TF+PKFIE+QFG+ +S A+ G +++P
Sbjct: 422 PRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPS 481
Query: 432 AALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGT 491
A +G +LGG+++ K ++ + + K A+ SGV+L CE+ G++ Y
Sbjct: 482 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 541
Query: 492 GEL----GNLIAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNP-VAHRKPKVYYNC 545
L NL CN NC C Y PVCG DG+ YF+PC AGC N + Y C
Sbjct: 542 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC 601
Query: 546 SCIERKTEITS------------TAETFGFE---AKAGKCETHCAKLPIFLCIFFIVIIF 590
+C++ + IT +T+ E A +GKC+ C L FL FIV
Sbjct: 602 TCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFI 661
Query: 591 TFMA 594
T A
Sbjct: 662 TACA 665
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 331 bits (849), Expect = 1e-90
Identities = 217/675 (32%), Positives = 323/675 (47%), Gaps = 76/675 (11%)
Query: 42 ENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRC 101
++S QEL++ P +P PS PS + + R F S +CL
Sbjct: 65 DSSGHQELKQGPNPL-APSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVV 123
Query: 102 NTPGG-FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSL 160
T FL+ C L Q ++V+G ++ I+T+E+RY +KSS +GL+ S +DI ++ +
Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183
Query: 161 FVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL----GSLFEDTCVTTRNST 216
FVS+FG RG +P WLA +I GA +F+LP F S Y++ S D NST
Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNST 243
Query: 217 ------SCTSSTSSLSNYLYV--FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
+C + ++++YV FI Q+L+G G TP+YTLG +LDD+V SSLY+
Sbjct: 244 ATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLA 303
Query: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328
Y M LGPA+GY+LGG L+ Y+D + ++DPR++G WW GFLL I + +
Sbjct: 304 IMYVMGALGPAVGYLLGGLLIGFYVDPR--NPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
Query: 329 IIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLV 388
I P FPK LP + + K KF LK N
Sbjct: 362 IFPMFTFPKKLPPRHKKKKKK-------------KFSVDAVSDDDVLKEKSNN------- 401
Query: 389 LSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRM 448
S ++ ++ + F + G +++P A +G +LGG+++ K ++
Sbjct: 402 -SEQADKKVS-----------------SMGFGKDVRGVIIVPSAGVGIVLGGYIIKKLKL 443
Query: 449 TCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGEL----GNLIAPCNAN 504
+ + K A+ SGV+L CE+ G++ Y L NL CN N
Sbjct: 444 GARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVN 503
Query: 505 CNCSRSYYYPVCG-DGVQYFSPCFAGCSNP-VAHRKPKVYYNCSCIERKTEITS------ 556
C C Y PVCG DG+ YF+PC AGC N + Y C+C++ + IT
Sbjct: 504 CGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQR 563
Query: 557 ------TAETFGFE---AKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVN 607
+T+ E A +GKC+ C L FL FIV T A + LR V
Sbjct: 564 SQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVE 623
Query: 608 HRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHM 667
+R ALG+QF++LR L IP PI FG ID+TC+LW +CG++G+CW Y+ +
Sbjct: 624 DEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFV 682
Query: 668 LVAISVTCKVITMFF 682
++ K + F
Sbjct: 683 YFGLAAGLKFVGFIF 697
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 325 bits (832), Expect = 1e-88
Identities = 183/615 (29%), Positives = 317/615 (51%), Gaps = 51/615 (8%)
Query: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
+ G + +I+ +E+R+++ SSL G+I S++I L+ FVS+FG + H+P+ +
Sbjct: 58 LAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCV 117
Query: 181 MIGLGALVFSLPQFFSGEYKL--------GSLFEDTCVT---------------TRNSTS 217
++G+G L+ ++PQFF +YK +L C+ ++ S
Sbjct: 118 IMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNE 177
Query: 218 CTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILG 277
C TSS S ++YVF LG LL G G TP+ LG A+LDD ++ YIG ++I+G
Sbjct: 178 CEVDTSS-SMWIYVF-LGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 235
Query: 278 PAIGYVLGGQLLTIYIDVAMG--ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCF 335
P G++LG +Y+D+ + +T DP+W+GAWW+G+L++ I + +PF
Sbjct: 236 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 295
Query: 336 PKHLPGTAEIQAGKTSQA-----------HQSNSNADVKFGKSIKDFPAALKNLMKNAVF 384
PK LP + + +S +Q+ + K + +DF +LKNL N V+
Sbjct: 296 PKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVY 355
Query: 385 MCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVS 444
+ +++ + G T+ PK+IE Q+G +SS A + G + IP ALG GG ++
Sbjct: 356 FLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMK 415
Query: 445 KFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGN----LIAP 500
KFR++ K L +S L CEN AG++ SY GT + L +
Sbjct: 416 KFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSD 475
Query: 501 CNANCNCSRSYYYPVCGD-GVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAE 559
CN+ C CS + + P+CG+ G+ Y S C AGC K ++YNC+C+ + ++
Sbjct: 476 CNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASK 530
Query: 560 TFGFEAKAGKCETH--CAKLPIFLCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALG 616
+ G+C+ C ++ ++ + ++ +T + G P + +LRC+ + +S ALG
Sbjct: 531 SGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALG 590
Query: 617 IQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCK 676
I + +R+L IP P+ FG ID++C+ W CG +G+C +YD+ H+ + ++V
Sbjct: 591 IYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILG 650
Query: 677 VITMFFNGFAIFLYK 691
+++ + +F+ K
Sbjct: 651 TVSILLSIAVLFILK 665
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 318 bits (816), Expect = 8e-87
Identities = 198/610 (32%), Positives = 310/610 (50%), Gaps = 61/610 (10%)
Query: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
F+L LL + Q ++ + S++T+EKR+ + SS +GLISS +IS +L +FVS+FG
Sbjct: 34 FVLCQGLLQLCQ-LLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSYFG 92
Query: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNST---------- 216
R H+PR + + GA + +LP F S Y+ T +T N++
Sbjct: 93 SRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQY------TLASTGNNSRLQAELCQKH 146
Query: 217 -------SCTSSTSS----LSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSL 265
C S+T + S+ + ++ QLL G G P+ G +++DD S L
Sbjct: 147 WQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSPL 206
Query: 266 YIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVT--EDDPRWLGAWWIGFLLSWI 323
YI +A+S+ GPA GY+LG +L I++D + V DPRW+GAWW+G L+S
Sbjct: 207 YISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISSA 266
Query: 324 FAWSLIIPFSCFP-------KHLPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALK 376
PF FP K P TA+ +A K +A S D IK FP
Sbjct: 267 LLVLTSFPFFFFPRAMPIGAKRAPATAD-EARKLEEAKSRGSLVDF-----IKRFPCIFL 320
Query: 377 NLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQ 436
L+ N++F+ +VL+ + + + G +TFL KF+E Q+G ++++A L GAV +P AALG
Sbjct: 321 RLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGM 380
Query: 437 ILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGN 496
+ GG L+ +F + + + A +++ L + C A V + + +
Sbjct: 381 LFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPP-STSSSIHP 439
Query: 497 LIAPCNANCNCSRSYYYPVCGD-GVQYFSPCFAGCSN---PVAHRKPKVYYNCSCIERKT 552
C +C+C S ++PVCGD G++Y SPC AGCSN A K +Y NCSC+ +
Sbjct: 440 QSPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCVTGGS 499
Query: 553 EITSTAETFGFEAKAGKCETHCAK--LPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQ 610
AK G C CA LP I F+ +I ++ P+ + +LR VN +
Sbjct: 500 A----------SAKTGSCPVPCAHFLLPAIFLISFVSLI-ACISHNPLYMMVLRVVNQEE 548
Query: 611 RSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVA 670
+S A+G+QF+++RLL +P P ++G TID +CI W+ G +GAC YDN + +
Sbjct: 549 KSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYLG 608
Query: 671 ISVTCKVITM 680
+ + K + M
Sbjct: 609 LQMGYKALGM 618
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 317 bits (813), Expect = 2e-86
Identities = 180/595 (30%), Positives = 307/595 (51%), Gaps = 51/595 (8%)
Query: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
+ G + +I+ +E+R+++ SSL G+I S++I L+ FVS+FG + H+P+ +
Sbjct: 58 LAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCV 117
Query: 181 MIGLGALVFSLPQFFSGEYKL--------GSLFEDTCVT---------------TRNSTS 217
++G+G L+ ++PQFF +YK +L C+ ++ S
Sbjct: 118 IMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNE 177
Query: 218 CTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILG 277
C TSS S ++YVF LG LL G G TP+ LG A+LDD ++ YIG ++I+G
Sbjct: 178 CEVDTSS-SMWIYVF-LGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 235
Query: 278 PAIGYVLGGQLLTIYIDVAMG--ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCF 335
P G++LG +Y+D+ + +T DP+W+GAWW+G+L++ I + +PF
Sbjct: 236 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 295
Query: 336 PKHLPGTAEIQAGKTSQA-----------HQSNSNADVKFGKSIKDFPAALKNLMKNAVF 384
PK LP + + +S +Q+ + K + +DF +LKNL N V+
Sbjct: 296 PKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVY 355
Query: 385 MCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVS 444
+ +++ + G T+ PK+IE Q+G +SS A + G + IP ALG GG ++
Sbjct: 356 FLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMK 415
Query: 445 KFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELG----NLIAP 500
KFR++ K L +S L CEN AG++ SY GT + L +
Sbjct: 416 KFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSD 475
Query: 501 CNANCNCSRSYYYPVCGD-GVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAE 559
CN+ C CS + + P+CG+ G+ Y S C AGC K ++YNC+C+ + ++
Sbjct: 476 CNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASK 530
Query: 560 TFGFEAKAGKC--ETHCAKLPIFLCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALG 616
+ G+C + C ++ ++ + ++ +T + G P + +LRC+ + +S ALG
Sbjct: 531 SGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALG 590
Query: 617 IQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
I + +R+L IP P+ FG ID++C+ W CG +G+C +YD+ + + +I
Sbjct: 591 IYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSI 645
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 303 bits (776), Expect = 4e-82
Identities = 177/592 (29%), Positives = 299/592 (50%), Gaps = 53/592 (8%)
Query: 126 VNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAFMIGLG 185
+ IS + +E+R+E+ SSL GLI S++I + +FVS+FG + H+P+ + F++G G
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 186 ALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTS------------------------CTSS 221
+++ +LP FF G Y+ E + NSTS C
Sbjct: 61 SILMALPHFFMGYYRYSK--ETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKE 118
Query: 222 TSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIG 281
+ S ++YVF +G +L G G TP+ LG +++DD SSLY+GT M + G
Sbjct: 119 SGS-HMWIYVF-MGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFA 176
Query: 282 YVLGGQLLTIYIDVAMGE--STDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFP--- 336
++LG +Y+D+ + + +T D RW+GAWW+GFL+S I + IPF P
Sbjct: 177 FMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNP 236
Query: 337 ----KHLPGTAEIQAGKTSQAHQSNSNADVK---FGKSIKDFPAALKNLMKNAVFMCLVL 389
K + + KT+ +N + K++ F +LK+++ N +++ V+
Sbjct: 237 NKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVI 296
Query: 390 STSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMT 449
T T++ K +E Q+G ++S L G + +P A+G GG+++ KF+++
Sbjct: 297 FTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLS 356
Query: 450 CKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLI----APCNANC 505
K A ++ V L ++ + CE++ AG++ +Y+G + + + + CN+ C
Sbjct: 357 LVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSEC 416
Query: 506 NCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFE 564
NC S + PVCG +G+ Y SPC AGC + +++P V+YNCSC+E + +
Sbjct: 417 NCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVE-----VIGLQNKNYS 471
Query: 565 AKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPIT---VSILRCVNHRQRSLALGIQFMV 621
A G+C A F I ++ F+ +T V ++R V ++LA+G M+
Sbjct: 472 AHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMI 531
Query: 622 LRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISV 673
+R LG I PI FG ID+TC+ W N CG +GAC IY++ + + V
Sbjct: 532 MRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKV 583
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 297 bits (761), Expect = 2e-80
Identities = 188/618 (30%), Positives = 308/618 (49%), Gaps = 67/618 (10%)
Query: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
F+L + LL + Q ++++G + SISTVEKR+ + S +GL++S ++ L +FVS+FG
Sbjct: 29 FVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFG 87
Query: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFED---------TCVTTRNSTS 217
R H+PR + + A ++ L L+ +LP F S Y+ + + C+ T ++ +
Sbjct: 88 SRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPA 147
Query: 218 CTSSTSSLSNY--------LYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGT 269
S + S+Y + + + Q LLG GG P+ G +++DD S LY+G
Sbjct: 148 SAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGI 207
Query: 270 GYAMSILGPAIGYVLGGQLLTIYIDV-AMGE-STDVTEDDPRWLGAWWIGFLLSWIFAWS 327
+A++++GP + + LG +L +Y+D+ M E +T DPRW+GAWW+GFL++
Sbjct: 208 LFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVAL 267
Query: 328 LIIPFSCFPKHLP---------------GTAEIQAGKTSQAHQSNSNADVKFG------- 365
IP+ FPK +P + + GK S + QS + K
Sbjct: 268 AAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAP 327
Query: 366 -----KSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
+ IK FP L +++ +F+ +VLS + + G ATFLPKF+E QF +T+S+A
Sbjct: 328 NLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYA 387
Query: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
L G + P +G ++GG LV + + L + L S + C +
Sbjct: 388 NLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQ 447
Query: 481 FAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDG--VQYFSPCFAGCSNPV---A 535
AG++ + L L C C+C + PVC V+Y +PC AGCS+ V A
Sbjct: 448 IAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDA 506
Query: 536 HRKPKVYY-NCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPI-FLCIFFIVIIFTFM 593
+V+Y NCSC+ G AG C++ C+ L + FL + + +
Sbjct: 507 LDNSQVFYTNCSCVVE-----------GNPVLAGSCDSTCSHLVVPFLLLVSLGSALACL 555
Query: 594 AGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIK 653
TP + ILR V ++LA+GIQFM LR+L +P P+I G ID+TC+ W ++ CG +
Sbjct: 556 THTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRR 614
Query: 654 GACWIYDNIKMAHMLVAI 671
C Y+N + + + +
Sbjct: 615 AVCRYYNNDLLRNRFIGL 632
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 297 bits (761), Expect = 2e-80
Identities = 188/618 (30%), Positives = 308/618 (49%), Gaps = 67/618 (10%)
Query: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
F+L + LL + Q ++++G + SISTVEKR+ + S +GL++S ++ L +FVS+FG
Sbjct: 51 FVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFG 109
Query: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFED---------TCVTTRNSTS 217
R H+PR + + A ++ L L+ +LP F S Y+ + + C+ T ++ +
Sbjct: 110 SRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPA 169
Query: 218 CTSSTSSLSNY--------LYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGT 269
S + S+Y + + + Q LLG GG P+ G +++DD S LY+G
Sbjct: 170 SAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGI 229
Query: 270 GYAMSILGPAIGYVLGGQLLTIYIDV-AMGE-STDVTEDDPRWLGAWWIGFLLSWIFAWS 327
+A++++GP + + LG +L +Y+D+ M E +T DPRW+GAWW+GFL++
Sbjct: 230 LFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVAL 289
Query: 328 LIIPFSCFPKHLP---------------GTAEIQAGKTSQAHQSNSNADVKFG------- 365
IP+ FPK +P + + GK S + QS + K
Sbjct: 290 AAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAP 349
Query: 366 -----KSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
+ IK FP L +++ +F+ +VLS + + G ATFLPKF+E QF +T+S+A
Sbjct: 350 NLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYA 409
Query: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
L G + P +G ++GG LV + + L + L S + C +
Sbjct: 410 NLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQ 469
Query: 481 FAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDG--VQYFSPCFAGCSNPV---A 535
AG++ + L L C C+C + PVC V+Y +PC AGCS+ V A
Sbjct: 470 IAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDA 528
Query: 536 HRKPKVYY-NCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPI-FLCIFFIVIIFTFM 593
+V+Y NCSC+ G AG C++ C+ L + FL + + +
Sbjct: 529 LDNSQVFYTNCSCVVE-----------GNPVLAGSCDSTCSHLVVPFLLLVSLGSALACL 577
Query: 594 AGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIK 653
TP + ILR V ++LA+GIQFM LR+L +P P+I G ID+TC+ W ++ CG +
Sbjct: 578 THTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRR 636
Query: 654 GACWIYDNIKMAHMLVAI 671
C Y+N + + + +
Sbjct: 637 AVCRYYNNDLLRNRFIGL 654
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 292 bits (748), Expect = 7e-79
Identities = 177/588 (30%), Positives = 287/588 (48%), Gaps = 35/588 (5%)
Query: 113 LLAVTQGIVVNGL----VNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGER 168
LLA+T V L +N ++ +E+++ + +SL G I+ S++I LL +FVS+FG +
Sbjct: 23 LLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTK 82
Query: 169 GHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL-------GSLFEDTCVTTRNSTSC--- 218
H+P + ++GLG + SLP F +Y+ G+L ++ + N T
Sbjct: 83 LHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRP 142
Query: 219 ----TSSTSSLSNYLYVFIL-GQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAM 273
+ T + + ++V++L G ++ G G TP+ LG ++++D S LYIG
Sbjct: 143 TQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETG 202
Query: 274 SILGPAIGYVLGGQLLTIYIDVAMGESTD--VTEDDPRWLGAWWIGFLLSWIFAWSLIIP 331
+I+GP IG +L +Y+D + D +T D RW+GAWW GFL+ IP
Sbjct: 203 AIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIP 262
Query: 332 FSCFPKHLPGTA-EIQAGKTSQAHQSNSNADVKFGKS--IKDFPAALKNLMKNAVFMCLV 388
F P LP E A ++ +VK K KDF +K+L N ++M +
Sbjct: 263 FFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFI 322
Query: 389 LSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRM 448
L + + +F+PK++E Q+G++SS A L G +P +G I+GG ++ KF++
Sbjct: 323 LVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKI 382
Query: 449 TCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGE----LGNLIAPCNAN 504
T K + S + L F+ CEN G++ SY G + ++ A CN +
Sbjct: 383 TVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVD 442
Query: 505 CNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGF 563
CNC + PVCG +G+ Y S C AGC + V+ NCSCI+ +++ G
Sbjct: 443 CNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTS---GNSSAVLGL 499
Query: 564 EAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLR 623
K C L FL + + +A P + +LRC+ ++SL +G+ R
Sbjct: 500 CDKGPDCS---LMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTR 556
Query: 624 LLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
+ IP PI FG +DSTC+ W CG GAC IYD+ ++ + +
Sbjct: 557 VFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 292 bits (748), Expect = 7e-79
Identities = 177/588 (30%), Positives = 287/588 (48%), Gaps = 35/588 (5%)
Query: 113 LLAVTQGIVVNGL----VNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGER 168
LLA+T V L +N ++ +E+++ + +SL G I+ S++I LL +FVS+FG +
Sbjct: 23 LLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTK 82
Query: 169 GHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL-------GSLFEDTCVTTRNSTSC--- 218
H+P + ++GLG + SLP F +Y+ G+L ++ + N T
Sbjct: 83 LHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRP 142
Query: 219 ----TSSTSSLSNYLYVFIL-GQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAM 273
+ T + + ++V++L G ++ G G TP+ LG ++++D S LYIG
Sbjct: 143 TQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETG 202
Query: 274 SILGPAIGYVLGGQLLTIYIDVAMGESTD--VTEDDPRWLGAWWIGFLLSWIFAWSLIIP 331
+I+GP IG +L +Y+D + D +T D RW+GAWW GFL+ IP
Sbjct: 203 AIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIP 262
Query: 332 FSCFPKHLPGTA-EIQAGKTSQAHQSNSNADVKFGKS--IKDFPAALKNLMKNAVFMCLV 388
F P LP E A ++ +VK K KDF +K+L N ++M +
Sbjct: 263 FFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFI 322
Query: 389 LSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRM 448
L + + +F+PK++E Q+G++SS A L G +P +G I+GG ++ KF++
Sbjct: 323 LVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKI 382
Query: 449 TCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGE----LGNLIAPCNAN 504
T K + S + L F+ CEN G++ SY G + ++ A CN +
Sbjct: 383 TVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVD 442
Query: 505 CNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGF 563
CNC + PVCG +G+ Y S C AGC + V+ NCSCI+ +++ G
Sbjct: 443 CNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTS---GNSSAVLGL 499
Query: 564 EAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLR 623
K C L FL + + +A P + +LRC+ ++SL +G+ R
Sbjct: 500 CDKGPDCS---LMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTR 556
Query: 624 LLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
+ IP PI FG +DSTC+ W CG GAC IYD+ ++ + +
Sbjct: 557 VFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 288 bits (738), Expect = 9e-78
Identities = 164/592 (27%), Positives = 298/592 (50%), Gaps = 54/592 (9%)
Query: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
+ G + +I+ +E+R+++ SSL G+I S++I L+ FVS+FG + H+P+ +
Sbjct: 58 LAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCV 117
Query: 181 MIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLG 240
++G+G L+ ++PQFF +YK + + +T + + C +SS
Sbjct: 118 IMGVGTLLIAMPQFFMEQYKY-ERYSPSSNSTLSISPCLLESSS---------------- 160
Query: 241 AGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMG-- 298
L + ++ S KS + G ++I+GP G++LG +Y+D+
Sbjct: 161 -------QLPVSVMEKS----KSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNL 209
Query: 299 ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQA----- 353
+ +T DP+W+GAWW+G+L++ I + +PF PK LP + + +S
Sbjct: 210 DHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFI 269
Query: 354 ------HQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPK 407
+Q+ + K + +DF +LKNL N V+ + +++ + G T+ PK
Sbjct: 270 IDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPK 329
Query: 408 FIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTL 467
+IE Q+G +SS A + G + IP ALG GG ++ KFR++ K L +S L
Sbjct: 330 YIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLL 389
Query: 468 SFVFMYAKCENEPFAGVSESYNGTGELGN----LIAPCNANCNCSRSYYYPVCGD-GVQY 522
CEN AG++ SY GT + L + CN+ C CS + + P+CG+ G+ Y
Sbjct: 390 FLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITY 449
Query: 523 FSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETH--CAKLPIF 580
S C AGC K ++YNC+C+ + +++ G+C+ C ++ ++
Sbjct: 450 VSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASKSGNSSGIVGRCQKDNGCPQMFLY 504
Query: 581 LCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTID 639
+ ++ +T + G P + +LRC+ + +S ALGI + +R+L IP P+ FG ID
Sbjct: 505 FLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLID 564
Query: 640 STCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYK 691
++C+ W CG +G+C +YD+ H+ + ++V +++ + +F+ K
Sbjct: 565 TSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 616
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 276 bits (707), Expect = 4e-74
Identities = 161/534 (30%), Positives = 269/534 (50%), Gaps = 51/534 (9%)
Query: 182 IGLGALVFSLPQFFSGEYKL--------GSLFEDTCVT---------------TRNSTSC 218
+G+G L+ ++PQFF +YK +L C+ ++ S C
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
Query: 219 TSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGP 278
TSS S ++YVF LG LL G G TP+ LG A+LDD ++ YIG ++I+GP
Sbjct: 61 EVDTSS-SMWIYVF-LGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGP 118
Query: 279 AIGYVLGGQLLTIYIDVAMG--ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFP 336
G++LG +Y+D+ + +T DP+W+GAWW+G+L++ I + +PF P
Sbjct: 119 IFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLP 178
Query: 337 KHLPGTAEIQAGKTSQA-----------HQSNSNADVKFGKSIKDFPAALKNLMKNAVFM 385
K LP + + +S +Q+ + K + +DF +LKNL N V+
Sbjct: 179 KSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYF 238
Query: 386 CLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSK 445
+ +++ + G T+ PK+IE Q+G +SS A + G + IP ALG GG ++ K
Sbjct: 239 LYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKK 298
Query: 446 FRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELG----NLIAPC 501
FR++ K L +S L CEN AG++ SY GT + L + C
Sbjct: 299 FRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDC 358
Query: 502 NANCNCSRSYYYPVCGD-GVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAET 560
N+ C CS + + P+CG+ G+ Y S C AGC K ++YNC+C+ + +++
Sbjct: 359 NSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASKS 413
Query: 561 FGFEAKAGKC--ETHCAKLPIFLCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALGI 617
G+C + C ++ ++ + ++ +T + G P + +LRC+ + +S ALGI
Sbjct: 414 GNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGI 473
Query: 618 QFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
+ +R+L IP P+ FG ID++C+ W CG +G+C +YD+ + + +I
Sbjct: 474 YTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSI 527
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 238 bits (608), Expect = 1e-62
Identities = 159/524 (30%), Positives = 251/524 (47%), Gaps = 50/524 (9%)
Query: 184 LGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLGAGG 243
+G + +PQ F L + + + S + T LS +F+ Q LLG GG
Sbjct: 1 MGPRIEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFV-AQTLLGVGG 59
Query: 244 TPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDV-AMGES-T 301
P+ G +++DD S LY+G +A++++GP + + LG +L +Y+D+ M E
Sbjct: 60 VPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGI 119
Query: 302 DVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTA-EIQ-------------- 346
+T DPRW+GAWW+GFL++ IP+ FPK +P E+Q
Sbjct: 120 SLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPAR 179
Query: 347 AGKTSQAHQSNSNADVKFG------------KSIKDFPAALKNLMKNAVFMCLVLSTSSE 394
GK S + QS + K + IK FP L +++ +F+ +VLS
Sbjct: 180 KGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCL 239
Query: 395 ALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTM 454
+ + G ATFLPKF+E QF +T+S+A L G + P +G ++GG LV + +
Sbjct: 240 SSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCG 299
Query: 455 KFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYP 514
L + L S + C + AG++ + L L C C+C + P
Sbjct: 300 ALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNP 358
Query: 515 VCGDG--VQYFSPCFAGCSNPV---AHRKPKVYY-NCSCIERKTEITSTAETFGFEAKAG 568
VC V+Y +PC AGCS+ V A +V+Y NCSC+ G AG
Sbjct: 359 VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVE-----------GNPVLAG 407
Query: 569 KCETHCAKLPI-FLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGT 627
C++ C+ L + FL + + + TP + ILR V ++LA+GIQFM LR+L
Sbjct: 408 SCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAW 467
Query: 628 IPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
+P P+I G ID+TC+ W ++ CG + C Y+N + + + +
Sbjct: 468 MPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLRNRFIGL 510
>gi|194239645 spinster homolog 3 [Homo sapiens]
Length = 512
Score = 38.9 bits (89), Expect = 0.017
Identities = 51/240 (21%), Positives = 88/240 (36%), Gaps = 44/240 (18%)
Query: 220 SSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPA 279
SS+ Y ++F L + ++G G T+ L D + + + Y +G
Sbjct: 127 SSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSG 186
Query: 280 IGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAW-WIGFLLSWIFAWSLIIPFSCFPKH 338
+GYVLG + + G W W ++ + A +LI+ P
Sbjct: 187 LGYVLGSAVTML-------------------TGNWRWALRVMPCLEAVALILLILLVPDP 227
Query: 339 LPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALIT 398
G AE Q +S+ DV++ L KN F+ L ++ A +T
Sbjct: 228 PRGAAETQGEGAVGGFRSSWCEDVRY-------------LGKNWSFVWSTLGVTAMAFVT 274
Query: 399 TGFATFLPKFIENQ---FGL--------TSSFAATLGGAVLIPGAALGQILGGFLVSKFR 447
+ PKF+ GL S+ + + GA+ I +G ILG +++
Sbjct: 275 GALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVIGVILGAEAARRYK 334
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 1 MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKS-P 59
+ S KG+ + SS S P Q VS+L S P + S +L++P+E + S P
Sbjct: 315 LSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSP--DFSAFPKLEQPEEDKYSKP 372
Query: 60 EPSLPSAPPNVS 71
PSAPP+ S
Sbjct: 373 TAPAPSAPPSPS 384
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 35.8 bits (81), Expect = 0.14
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 12 FVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQK--SPEPSLPSAPPN 69
F+ P +L PS+ + S ++ PQ+L P P+ SP P P P+
Sbjct: 408 FLLEKPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPS 467
Query: 70 VSEEKLRSLSLSEFEEGSYGWRNFHP 95
+ + R+ SLS F + G R P
Sbjct: 468 LGPDGTRTFSLSPFPSLASGERLMMP 493
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 21 RRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEP--SLPSAPPNVSEEKLRSL 78
RR S SP+ IE+ S+ R QP E + ++SP P + P +P VS E+
Sbjct: 32271 RRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSER---- 32326
Query: 79 SLSEFEEGS 87
SLS FE +
Sbjct: 32327 SLSRFERSA 32335
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 21 RRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEP--SLPSAPPNVSEEKLRSL 78
RR S SP+ IE+ S+ R QP E + ++SP P + P +P VS E+
Sbjct: 25966 RRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSER---- 26021
Query: 79 SLSEFEEGS 87
SLS FE +
Sbjct: 26022 SLSRFERSA 26030
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 21 RRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEP--SLPSAPPNVSEEKLRSL 78
RR S SP+ IE+ S+ R QP E + ++SP P + P +P VS E+
Sbjct: 25899 RRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSER---- 25954
Query: 79 SLSEFEEGS 87
SLS FE +
Sbjct: 25955 SLSRFERSA 25963
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 21 RRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEP--SLPSAPPNVSEEKLRSL 78
RR S SP+ IE+ S+ R QP E + ++SP P + P +P VS E+
Sbjct: 25774 RRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSER---- 25829
Query: 79 SLSEFEEGS 87
SLS FE +
Sbjct: 25830 SLSRFERSA 25838
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 35.0 bits (79), Expect = 0.24
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 14/93 (15%)
Query: 1 MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQP-------QELQKPQ 53
MK A G +LA VPSSP +L +P + S PQ + + P Q+L K
Sbjct: 642 MKRALG-GDLAPVPSSPQ--PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 54 EPQKSP----EPSLPSAPPNVSEEKLRSLSLSE 82
EP+K P +P+L +P +++ + SLS+
Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK 731
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 35.0 bits (79), Expect = 0.24
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 14/93 (15%)
Query: 1 MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQP-------QELQKPQ 53
MK A G +LA VPSSP +L +P + S PQ + + P Q+L K
Sbjct: 642 MKRALG-GDLAPVPSSPQ--PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 54 EPQKSP----EPSLPSAPPNVSEEKLRSLSLSE 82
EP+K P +P+L +P +++ + SLS+
Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,876,290
Number of Sequences: 37866
Number of extensions: 1288977
Number of successful extensions: 6442
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 6026
Number of HSP's gapped (non-prelim): 299
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.