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Search of human proteins with 124249372
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124249372 PRAME family member 12 [Homo sapiens]
(483 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124249372 PRAME family member 12 [Homo sapiens] 982 0.0
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 802 0.0
gi|59676587 PRAME family member 8 [Homo sapiens] 800 0.0
gi|59676593 PRAME family member 7 [Homo sapiens] 799 0.0
gi|61696142 PRAME family member 5 [Homo sapiens] 575 e-164
gi|58219004 PRAME family member 6 [Homo sapiens] 575 e-164
gi|153792112 PRAME family member 20 [Homo sapiens] 572 e-163
gi|153945800 PRAME family member 21 [Homo sapiens] 572 e-163
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 571 e-163
gi|148356236 PRAME family member 15 [Homo sapiens] 570 e-163
gi|61102721 PRAME family member 9 [Homo sapiens] 570 e-163
gi|59958373 PRAME family member 4 [Homo sapiens] 561 e-160
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 556 e-158
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 550 e-157
gi|226437621 PRAME family member 11 [Homo sapiens] 498 e-141
gi|154800493 PRAME family member 22 [Homo sapiens] 476 e-134
gi|153791443 PRAME family member 18 [Homo sapiens] 472 e-133
gi|194306638 PRAME family member 3 [Homo sapiens] 470 e-132
gi|194306635 PRAME family member 19 [Homo sapiens] 468 e-132
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 468 e-132
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 468 e-132
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 468 e-132
gi|46249367 preferentially expressed antigen in melanoma [Homo s... 468 e-132
gi|5174641 preferentially expressed antigen in melanoma [Homo sa... 468 e-132
gi|66954681 PRAME family member 13 [Homo sapiens] 464 e-131
gi|12738831 PRAME family member 1 [Homo sapiens] 464 e-130
gi|194018546 PRAME family member 10 [Homo sapiens] 460 e-129
gi|88942379 PREDICTED: PRAME family member [Homo sapiens] 448 e-126
gi|12738834 PRAME family member 2 [Homo sapiens] 448 e-126
gi|157426839 PRAME family member 17 [Homo sapiens] 447 e-125
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 982 bits (2538), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC 180
ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC
Sbjct: 121 ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC 180
Query: 181 KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI 240
KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI
Sbjct: 181 KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI 240
Query: 241 HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT 300
HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT
Sbjct: 241 HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT 300
Query: 301 ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI 360
ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI
Sbjct: 301 ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI 360
Query: 361 VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA 420
VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA
Sbjct: 361 VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA 420
Query: 421 QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACCQG 480
QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACCQG
Sbjct: 421 QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACCQG 480
Query: 481 GFI 483
GFI
Sbjct: 481 GFI 483
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 802 bits (2071), Expect = 0.0
Identities = 397/473 (83%), Positives = 426/473 (90%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++APPRLLELA Q LLRD+ALAI T+EELPRELFP LFMEAF+RR CETL TMVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FT LPLGSLMKS +LE ++VLEG+D LL Q+VRPR+ KLQVLDLRNVDENF I+SGA+
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC 180
A PEALS+++TA NCP G QQP MV +DLC KN LDECLTH LEWGKQRKGLLHVCC
Sbjct: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
Query: 181 KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI 240
KELQ+FG+ IH IIEVLN VELDCIQEVEVCCPWELS L++FAPYLGQMRNLRKLVLFNI
Sbjct: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
Query: 241 HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT 300
SACIP D K QF+ +FTSQFLKLDYFQ L MHSVSFLEGHLDQLLRCLQA LE VVMT
Sbjct: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
Query: 301 ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI 360
+CLLSESDLKHLSWCPSIRQLKELDLRG+TLTHFSPEPL+ LLEQ ATLQTLDLEDCGI
Sbjct: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
Query: 361 VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA 420
+DSQLSAILP LSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYD
Sbjct: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
Query: 421 QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
QGALCWGRF++LGAELMKTLRDLRQPKIIVF TVPCPRCGIRASYDLEPSHCL
Sbjct: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 800 bits (2067), Expect = 0.0
Identities = 396/473 (83%), Positives = 426/473 (90%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++APPRLLELA Q LLRD+ALAI T+EELPRELFP LFMEAF+RR CETL TMVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FT LPLGSLMKS +LE ++VLEG+D LL Q+VRPR+ KLQVLDLRNVDENF I+SGA+
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC 180
A PEALS+++TA NCP G QQP MV +DLC KN LDECLTH LEWGKQRKGLLHVCC
Sbjct: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
Query: 181 KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI 240
+ELQ+FG+ IH IIEVLN VELDCIQEVEVCCPWELS L++FAPYLGQMRNLRKLVLFNI
Sbjct: 181 QELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
Query: 241 HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT 300
SACIP D K QF+ +FTSQFLKLDYFQ L MHSVSFLEGHLDQLLRCLQA LE VVMT
Sbjct: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
Query: 301 ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI 360
+CLLSESDLKHLSWCPSIRQLKELDLRG+TLTHFSPEPL+ LLEQ ATLQTLDLEDCGI
Sbjct: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
Query: 361 VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA 420
+DSQLSAILP LSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYD
Sbjct: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
Query: 421 QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
QGALCWGRF++LGAELMKTLRDLRQPKIIVF TVPCPRCGIRASYDLEPSHCL
Sbjct: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 799 bits (2064), Expect = 0.0
Identities = 396/473 (83%), Positives = 425/473 (89%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++APPRLLELA Q LLRD+ALAI T+EELPRELFP LFMEAF+RR CETL TMVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FT LPLGSLMKS +LE ++VLEG+D LL Q+VRPR+ KLQVLDLRNVDENF I+SGA+
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC 180
A PEALS+++TA NCP G QQP MV +DLC KN LDECLTH LEWGKQRKGLLHVCC
Sbjct: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
Query: 181 KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI 240
KELQ+FG+ IH IIEVLN VELDCIQEVEVCCPWELS L++FAPYLGQMRNLRKLVLFNI
Sbjct: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
Query: 241 HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT 300
SACIP D K QF+ +FTSQFLKLDYFQ L MHSVSFLEGHLDQLLRCLQA LE VVMT
Sbjct: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
Query: 301 ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI 360
+CLLSESDLKHLSWCPSIRQLKELDLRG+TLTHFSPEPL+ LLEQ ATLQTLDLEDCGI
Sbjct: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
Query: 361 VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA 420
+DSQLSAILP LSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYD
Sbjct: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
Query: 421 QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
QGALCWGRF++LGAELMKT RDLRQPKIIVF TVPCPRCGIRASYDLEPSHCL
Sbjct: 421 QGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 575 bits (1482), Expect = e-164
Identities = 300/480 (62%), Positives = 356/480 (74%), Gaps = 6/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL Q V PRRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR + +CPR GQQPL V ++L KN LDE LT L W KQRK LLH+
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKL M+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALSRC +L+TFSFCGN ISMA LENLL HT+ L L +ELYPAP ESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
DA G LCW RF+Q+ AELMK +RDLR PK I+F T CP CG R+ YDLE C CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC----CC 476
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 575 bits (1481), Expect = e-164
Identities = 300/480 (62%), Positives = 355/480 (73%), Gaps = 6/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL Q V PRRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSPEALSKRRTAG--NCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR +CPR GQQPL V ++L KN LDE LT L W KQRK LLH+
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKL M+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALSRC +L+TFSFCGN ISMA LENLL HT+ L L +ELYPAP ESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
DA G LCW RF+Q+ AELMK +RDLR PK I+F T CP CG R+ YDLE C CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC----CC 476
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 572 bits (1475), Expect = e-163
Identities = 301/480 (62%), Positives = 355/480 (73%), Gaps = 7/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD ALAI TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPLGSLMK E F+AVL+GLDALL +VR RRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A P A+ R+ +CPR GQQPL V +DLC KN LDE T W KQR+GL+H+
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L++ G+ H I +L TV LDCIQEVEV C W L +L F PYLGQMRNLRKLVL
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
+I S I ++K++FV QFT+QFLKL QKLYM+SVSFLEGHLDQ+L CL+ L +
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS PSI QLK LDL G L +FS PL VLLE+ ATL+ LDL+DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GIVDSQ++AILPALSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
D +G +C RF+QLGAELM +R LR+P+ I+F T CP+CG R+ YDLE C CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC----CC 475
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 572 bits (1475), Expect = e-163
Identities = 301/480 (62%), Positives = 355/480 (73%), Gaps = 7/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD ALAI TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPLGSLMK E F+AVL+GLDALL +VR RRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A P A+ R+ +CPR GQQPL V +DLC KN LDE T W KQR+GL+H+
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L++ G+ H I +L TV LDCIQEVEV C W L +L F PYLGQMRNLRKLVL
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
+I S I ++K++FV QFT+QFLKL QKLYM+SVSFLEGHLDQ+L CL+ L +
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS PSI QLK LDL G L +FS PL VLLE+ ATL+ LDL+DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GIVDSQ++AILPALSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
D +G +C RF+QLGAELM +R LR+P+ I+F T CP+CG R+ YDLE C CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC----CC 475
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 571 bits (1472), Expect = e-163
Identities = 299/480 (62%), Positives = 354/480 (73%), Gaps = 6/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL Q V PRRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR + +CPR GQQPL V ++L KN LDE LT L W KQRK LLH+
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKL M+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALS C +L+TFSFCGN ISMA LENLL HT+ L L +ELYPAP ESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
DA G LCW RF Q+ AELMK +RDLR PK I+F T CP CG R+ YDLE C CC
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC----CC 476
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 570 bits (1470), Expect = e-163
Identities = 295/470 (62%), Positives = 353/470 (75%), Gaps = 2/470 (0%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL Q VRPRRWKLQVLDL++V ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR + +CPR G+QPL V ++L KN LDE LT+ L W KQRK LLH+
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
A G LCW RF+Q+ AELM +RDLR PK I+F T CP CG R+ YDLE
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 570 bits (1470), Expect = e-163
Identities = 295/470 (62%), Positives = 353/470 (75%), Gaps = 2/470 (0%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL Q VRPRRWKLQVLDL++V ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR + +CPR G+QPL V ++L KN LDE LT+ L W KQRK LLH+
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
A G LCW RF+Q+ AELM +RDLR PK I+F T CP CG R+ YDLE
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 561 bits (1447), Expect = e-160
Identities = 292/470 (62%), Positives = 350/470 (74%), Gaps = 2/470 (0%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS+ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL VRPRRWKLQVLDL++V ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR + +CPR G+QPL V ++L KN LDE LT L W KQRK LLH+
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KL+L
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
A G LCW RF+Q+ AELM +RDLR PK I+F T CP CG R+ YDLE
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 556 bits (1434), Expect = e-158
Identities = 291/470 (61%), Positives = 348/470 (74%), Gaps = 2/470 (0%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS++ PPRLLEL +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPL L+K LE F+AVL+GLDALL Q VRPRRWKLQVLDL++V ENFW +WS A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ALSPEALSKRRTAG--NCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
A +KR +CPR +QPL V ++L KN LDE LT L W KQR+ LLH+
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG +RNL+KLVL
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
++ VS + ++K++ V QFT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L L LELYPAP ESY
Sbjct: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
A G LCW RF+Q+ AELMK +R LR PK I+F T CP G R+ YDLE
Sbjct: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLE 507
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 550 bits (1418), Expect = e-157
Identities = 289/473 (61%), Positives = 352/473 (74%), Gaps = 10/473 (2%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MSLQAP RLLELA QSLL D+ALAI L+ELPRELFPPLF+EAFT R CE L MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRR KLQVL+LR+VDENFW IWSGA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+G +H+
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
CC ++ + ++I +L TV D IQ +E+ C P +++ F+PYL QMRNLRKL
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSPYLSQMRNLRKL 237
Query: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
+ + + D +EQ + FT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+
Sbjct: 238 FISD-GCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 295
Query: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
+ +T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL
Sbjct: 296 VLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDL 355
Query: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
+DCGI+DSQ++AILPALSRC +L+TFSFCGN ISMA LENLL HT+ L L LELYPAP
Sbjct: 356 DDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPR 415
Query: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
ESY A G LCW RF+Q+ AELMK +RDLR PK I+F T CP CG R+ YDLE
Sbjct: 416 ESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 498 bits (1283), Expect = e-141
Identities = 261/430 (60%), Positives = 313/430 (72%), Gaps = 2/430 (0%)
Query: 41 MEAFTRRCCETLTTMVQAWPFTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKL 100
MEAF+RR CE L MVQAWPF LPL L+K LE F+AVL+GLDALL Q VRPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLDLRNVDENFWGIWSGASALSPEALSKRRTAG--NCPRPGGQQPLMVILDLCFKNGML 158
QVLDL++V ENFW +WS A A +KR +CPR +QPL V ++L KN L
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 159 DECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSI 218
DE LT L W KQR+ LLH+CCK+L+I G+ I +L V LDCIQEVEV C W L I
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 219 LIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSF 278
L +F PYLG +RNL+KLVL ++ VS + ++K++ V QFT+QFLKL QKLYM+SVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
Query: 279 LEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEP 338
LEGHLDQLL CL+ L+ + +T C+L ESDLKHLS CPSI QLK LDL GI LT++S P
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
Query: 339 LSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLR 398
L +LLE+ ATL+ LDL+DCGI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
Query: 399 HTVGLSKLSLELYPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPR 458
HT+ L L LELYPAP ESY A G LCW RF+Q+ AELMK +R LR PK I+F T CP
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
Query: 459 CGIRASYDLE 468
G R+ YDLE
Sbjct: 421 HGDRSFYDLE 430
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 476 bits (1225), Expect = e-134
Identities = 261/478 (54%), Positives = 327/478 (68%), Gaps = 9/478 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MSLQAP RLLELA QSLL D+ALAI L+ELPRELFPPLF+EAFT R CE L MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRRWKLQVL+LR+VDENFW IWSGA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+G +H+
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
CC ++ + ++I +L TV D IQ +E+ C P +++ F+ YL QMRNLRKL
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
Query: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
+ + + D +EQ V +F+S L+L+Y Q LY+ V F GHLDQL+RCL++PLE
Sbjct: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
Query: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
T+ +T L + DLK L PS+ QLK+L+L L EPL LLE+ ATLQTL L
Sbjct: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
Query: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
DCGI DS+L ILPALS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
Query: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
ES D +G + + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 472 bits (1214), Expect = e-133
Identities = 261/481 (54%), Positives = 329/481 (68%), Gaps = 15/481 (3%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS QAP RLLELA QSLLRD+ALAI L+ELPRELFP LF+EAFT R CE L MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRRWKLQVL++R+VDENFW IWSGA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+ +H+
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
CC ++ + + I +L TV D IQ +E+ C P ++ + R YL QM+NLRKL
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
Query: 236 VLFNIHVSAC--IP-LDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQA 292
+ + C +P + + Q V +F+S FL+L+Y Q LYM + F EG+LDQL+RCL++
Sbjct: 238 FISD----GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKS 293
Query: 293 PLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQT 352
PLET+ +T L E DLK L W PS+ QLK+L+L TL EPL LLE+ ATLQT
Sbjct: 294 PLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQT 353
Query: 353 LDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYP 412
L L DCGI DS+L ILPALSRCS L+TF F GN SM L++LLRHT LS LSLE YP
Sbjct: 354 LFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYP 413
Query: 413 APLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHC 472
AP ES D +G + + L AELM+ LR++R+P I F V CP CG+ + LE + C
Sbjct: 414 APRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
Query: 473 L 473
L
Sbjct: 474 L 474
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 470 bits (1209), Expect = e-132
Identities = 260/478 (54%), Positives = 325/478 (67%), Gaps = 9/478 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MSLQAP RLLELA QSLL D+ALAI L+ELPRELFPPLF+EAFT R CE L MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRR KLQVL+LR+VDENFW IWSGA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+G +H+
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
CC ++ + ++I +L TV D IQ +E+ C P +++ F YL QMRNLRKL
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFIRYLSQMRNLRKL 239
Query: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
+ + + D +EQ V +F+S L+L+Y Q LY+ V F GHLDQL+RCL++PLE
Sbjct: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
Query: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
T+ +T L + DLK L PS+ QLK+L+L L EPL LLE+ ATLQTL L
Sbjct: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
Query: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
DCGI DS+L ILPALS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
Query: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
ES D +G + + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 468 bits (1205), Expect = e-132
Identities = 260/481 (54%), Positives = 328/481 (68%), Gaps = 15/481 (3%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS QAP RLLELA QSLLRD+ALAI L+ELPRELFP LF+EAFT R CE L MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRRWKLQVL++R+VDENFW IWSGA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+ +H+
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
CC ++ + + I +L TV D IQ +E+ C P ++ + R YL QM+NLRKL
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
Query: 236 VLFNIHVSAC--IP-LDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQA 292
+ + C +P + + Q V +F+S FL+L+Y Q LYM + F EG+LDQL+RCL++
Sbjct: 238 FISD----GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKS 293
Query: 293 PLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQT 352
PLET+ +T L E DLK L W PS+ QLK+L+L TL EPL LLE+ ATLQT
Sbjct: 294 PLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQT 353
Query: 353 LDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYP 412
L L DCGI S+L ILPALSRCS L+TF F GN SM L++LLRHT LS LSLE YP
Sbjct: 354 LFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYP 413
Query: 413 APLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHC 472
AP ES D +G + + L AELM+ LR++R+P I F V CP CG+ + LE + C
Sbjct: 414 APRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
Query: 473 L 473
L
Sbjct: 474 L 474
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 468 bits (1204), Expect = e-132
Identities = 255/482 (52%), Positives = 327/482 (67%), Gaps = 14/482 (2%)
Query: 5 APPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCL 64
+P RL+ELA QSLL+D ALAI LE LPRELFPPLFM AF R +TL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKS--CNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLR-NVDENFWGIWSGASA 121
PLG LMK +LE F+AVL+GLD LLAQ+VRPRRWKLQVLDLR N ++FW +WSG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 L-----SPEA---LSKRRTAGNCPRPGGQQ--PLMVILDLCFKNGMLDECLTHFLEWGKQ 171
PEA ++K+R Q P+ V++DL K G DE ++ +E K+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 172 RKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRN 231
+K +L +CCK+L+IF + + I +L V+LD I+++EV C W+L L +F+PYLGQM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 232 LRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQ 291
LR+L+L +IH S+ I +++EQ++ QFTSQFL L Q LY+ S+ FL G LDQLLR +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 292 APLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQ 351
PLET+ +T C LSE D+ HLS PS+ QL L L G+ LT SPEPL LLE+A ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 352 TLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
L ++CGI D QL A+LP+LS CSQL+T SF GN IS++AL++LL+H +GLS L+ LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 412 PAPLESY-DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPS 470
P PLESY D G L R + L A L + L +L +P ++ S PCP CG R YD EP
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 471 HC 472
C
Sbjct: 502 LC 503
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 468 bits (1204), Expect = e-132
Identities = 255/482 (52%), Positives = 327/482 (67%), Gaps = 14/482 (2%)
Query: 5 APPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCL 64
+P RL+ELA QSLL+D ALAI LE LPRELFPPLFM AF R +TL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKS--CNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLR-NVDENFWGIWSGASA 121
PLG LMK +LE F+AVL+GLD LLAQ+VRPRRWKLQVLDLR N ++FW +WSG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 L-----SPEA---LSKRRTAGNCPRPGGQQ--PLMVILDLCFKNGMLDECLTHFLEWGKQ 171
PEA ++K+R Q P+ V++DL K G DE ++ +E K+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 172 RKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRN 231
+K +L +CCK+L+IF + + I +L V+LD I+++EV C W+L L +F+PYLGQM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 232 LRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQ 291
LR+L+L +IH S+ I +++EQ++ QFTSQFL L Q LY+ S+ FL G LDQLLR +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 292 APLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQ 351
PLET+ +T C LSE D+ HLS PS+ QL L L G+ LT SPEPL LLE+A ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 352 TLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
L ++CGI D QL A+LP+LS CSQL+T SF GN IS++AL++LL+H +GLS L+ LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 412 PAPLESY-DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPS 470
P PLESY D G L R + L A L + L +L +P ++ S PCP CG R YD EP
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 471 HC 472
C
Sbjct: 502 LC 503
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 468 bits (1204), Expect = e-132
Identities = 255/482 (52%), Positives = 327/482 (67%), Gaps = 14/482 (2%)
Query: 5 APPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCL 64
+P RL+ELA QSLL+D ALAI LE LPRELFPPLFM AF R +TL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKS--CNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLR-NVDENFWGIWSGASA 121
PLG LMK +LE F+AVL+GLD LLAQ+VRPRRWKLQVLDLR N ++FW +WSG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 L-----SPEA---LSKRRTAGNCPRPGGQQ--PLMVILDLCFKNGMLDECLTHFLEWGKQ 171
PEA ++K+R Q P+ V++DL K G DE ++ +E K+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 172 RKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRN 231
+K +L +CCK+L+IF + + I +L V+LD I+++EV C W+L L +F+PYLGQM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 232 LRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQ 291
LR+L+L +IH S+ I +++EQ++ QFTSQFL L Q LY+ S+ FL G LDQLLR +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 292 APLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQ 351
PLET+ +T C LSE D+ HLS PS+ QL L L G+ LT SPEPL LLE+A ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 352 TLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
L ++CGI D QL A+LP+LS CSQL+T SF GN IS++AL++LL+H +GLS L+ LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 412 PAPLESY-DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPS 470
P PLESY D G L R + L A L + L +L +P ++ S PCP CG R YD EP
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 471 HC 472
C
Sbjct: 502 LC 503
>gi|46249367 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 468 bits (1204), Expect = e-132
Identities = 255/482 (52%), Positives = 327/482 (67%), Gaps = 14/482 (2%)
Query: 5 APPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCL 64
+P RL+ELA QSLL+D ALAI LE LPRELFPPLFM AF R +TL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKS--CNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLR-NVDENFWGIWSGASA 121
PLG LMK +LE F+AVL+GLD LLAQ+VRPRRWKLQVLDLR N ++FW +WSG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 L-----SPEA---LSKRRTAGNCPRPGGQQ--PLMVILDLCFKNGMLDECLTHFLEWGKQ 171
PEA ++K+R Q P+ V++DL K G DE ++ +E K+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 172 RKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRN 231
+K +L +CCK+L+IF + + I +L V+LD I+++EV C W+L L +F+PYLGQM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 232 LRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQ 291
LR+L+L +IH S+ I +++EQ++ QFTSQFL L Q LY+ S+ FL G LDQLLR +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 292 APLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQ 351
PLET+ +T C LSE D+ HLS PS+ QL L L G+ LT SPEPL LLE+A ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 352 TLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
L ++CGI D QL A+LP+LS CSQL+T SF GN IS++AL++LL+H +GLS L+ LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 412 PAPLESY-DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPS 470
P PLESY D G L R + L A L + L +L +P ++ S PCP CG R YD EP
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 471 HC 472
C
Sbjct: 502 LC 503
>gi|5174641 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 468 bits (1204), Expect = e-132
Identities = 255/482 (52%), Positives = 327/482 (67%), Gaps = 14/482 (2%)
Query: 5 APPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCL 64
+P RL+ELA QSLL+D ALAI LE LPRELFPPLFM AF R +TL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKS--CNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLR-NVDENFWGIWSGASA 121
PLG LMK +LE F+AVL+GLD LLAQ+VRPRRWKLQVLDLR N ++FW +WSG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 L-----SPEA---LSKRRTAGNCPRPGGQQ--PLMVILDLCFKNGMLDECLTHFLEWGKQ 171
PEA ++K+R Q P+ V++DL K G DE ++ +E K+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 172 RKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRN 231
+K +L +CCK+L+IF + + I +L V+LD I+++EV C W+L L +F+PYLGQM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 232 LRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQ 291
LR+L+L +IH S+ I +++EQ++ QFTSQFL L Q LY+ S+ FL G LDQLLR +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 292 APLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQ 351
PLET+ +T C LSE D+ HLS PS+ QL L L G+ LT SPEPL LLE+A ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 352 TLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
L ++CGI D QL A+LP+LS CSQL+T SF GN IS++AL++LL+H +GLS L+ LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 412 PAPLESY-DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPS 470
P PLESY D G L R + L A L + L +L +P ++ S PCP CG R YD EP
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 471 HC 472
C
Sbjct: 502 LC 503
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 464 bits (1195), Expect = e-131
Identities = 257/480 (53%), Positives = 326/480 (67%), Gaps = 8/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLFMEAF RR +TLT MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FTCLPLGSLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
ALS PE +SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CC +L + I + + L + L+ IQ++E+ ++ + YL +M+NLRKLV
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
H S + + + V +F+S FL+L++ Q L + ++F GHL+QL+RCLQ PLE +
Sbjct: 241 RCHHSMS-DNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T L E D+K LS PS+ LK L+L + L S EPL LLE+ A+L+TL LE C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
I SQLSAILP LS CSQL+TF F N +SM AL++LLRHT GLSKLSLE YPAP ES
Sbjct: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
++ + W F+ L AELM TLR++RQPK I PCP CG S +LE L+ CC
Sbjct: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELE-----LHLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 464 bits (1193), Expect = e-130
Identities = 258/480 (53%), Positives = 327/480 (68%), Gaps = 8/480 (1%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLFMEAF+RR +TLT MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FTCLPLGSLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
ALS PE SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CC +L + I + + L + L+ IQE+E+ ++ + YL +M+NLRKLV
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
H + + + V +F+S FL+L++ Q L + ++F GHL+QL+RCLQ PLE +
Sbjct: 241 RCHHYTS-DNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
+T L E D+K LS PS+ LK L+L + L S EPL LLE+ A+L+TL LE C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGC 359
Query: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
I SQLSAILPALSRCSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP ES
Sbjct: 360 QIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
++ + W F+ L AELM TLR++RQPK I PCP CG S +LE L+ CC
Sbjct: 420 NSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELE-----LHLCC 474
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 460 bits (1183), Expect = e-129
Identities = 256/470 (54%), Positives = 318/470 (67%), Gaps = 19/470 (4%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MSLQAP RLLELA QSLLR++ L I TL+ELPRE+FP +FMEAF+ R E L MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPLGSLMK+ +LE +AVL GLD L+AQKVRPRRWKLQVLDLR+VDENFW IWSGA
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
LS PEA+SKR+T +CPR G QPL V +DLC K LDECL++ W R+GL+H+
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CC ++Q + + +L + D IQE+EV L+ +FAPYL QM NLR+L L
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 239 -----NIHVSA---CIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCL 290
++VS CIP S FL L Y Q LY+ +S ++ HL+ LLR L
Sbjct: 241 FGYERELYVSVQWPCIP---------DLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYL 291
Query: 291 QAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATL 350
+ PL + ++ L++ D++ LS PS+ QLKEL L I + EPL VLLE+ ATL
Sbjct: 292 KNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATL 351
Query: 351 QTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
+TL L+DC I D QL +LPALS CSQL+TF+F GN SM AL++LLRHT GLSKL LEL
Sbjct: 352 KTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLEL 411
Query: 411 YPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCG 460
YPAPLES D +G + W + + AELM+TLR++RQPK I F VPCP CG
Sbjct: 412 YPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
Length = 395
Score = 448 bits (1152), Expect = e-126
Identities = 230/375 (61%), Positives = 277/375 (73%), Gaps = 2/375 (0%)
Query: 96 RRWKLQVLDLRNVDENFWGIWSGASALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCF 153
RRWKLQVLDL++V ENFW +WS A A +KR + +CPR G+QPL V ++L
Sbjct: 15 RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
Query: 154 KNGMLDECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCP 213
KN LDE LT L W KQRK LLH+CCK+L+I G+ I +L V LDCIQEVEV C
Sbjct: 75 KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
Query: 214 WELSILIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYM 273
W L IL +F PYLG MRNL+KLVL ++ VS + ++K++ V QFT+QFLKL QKLYM
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
Query: 274 HSVSFLEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTH 333
+SVSFLEGHLDQLL CL+ L+ + +T C+L ESDLKHLS CPSI QLK LDL GI LT+
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
Query: 334 FSPEPLSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAAL 393
+S PL +LLE+ ATL+ LDL+DCGI+DSQ++AILPALSRC +L+TFSFCGN ISMA L
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
Query: 394 ENLLRHTVGLSKLSLELYPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFST 453
ENLL HT+ L L LELYPAP ESY A G LCW RF+Q+ AELMK +RDLR PK I+F T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
Query: 454 VPCPRCGIRASYDLE 468
CP CG R+ YDLE
Sbjct: 375 DYCPDCGNRSFYDLE 389
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 448 bits (1152), Expect = e-126
Identities = 255/483 (52%), Positives = 322/483 (66%), Gaps = 14/483 (2%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLF EAF+RR +TLT MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
FTCLPL SLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
ALS PEA+SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
CC +L + I + + L + ++ I E+E+ C P ++ + YL +M+ L KL
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP---HLIRKLYCYLKEMKTLCKL 237
Query: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
V H + + V +FTS FL+L++ Q L + ++F GHL+QL+RCLQ PLE
Sbjct: 238 VFSRCHHYTS-DNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
Query: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
+ +T L E DLK LS PS+ LK L+L + L S EPL LLE+ A+L+TL L
Sbjct: 297 NLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVL 356
Query: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
E C I SQLSAILP LS CSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP
Sbjct: 357 EGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
Query: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLN 475
ES ++ + W F+ L AELM TLR+ RQPK I PCP CG S +LE L+
Sbjct: 417 ESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELE-----LH 471
Query: 476 ACC 478
CC
Sbjct: 472 LCC 474
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 447 bits (1149), Expect = e-125
Identities = 250/467 (53%), Positives = 313/467 (67%), Gaps = 13/467 (2%)
Query: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
MSLQ+P RLLELA QSLLR++ L I L+ELPRE+FP +FMEA + R E L MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
F LPLGSLMK+ +LE +AVL+GLD LLAQK+RPRRWKLQVLDLR+VD NFW IWSGA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
ALS PEA+SKR+T + PR G QPL V +DLC K LDECL++ W R+GL+H+
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
CC ++Q + + +L V D IQE+E+ L+ +FAPYL QM NLRKL L
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 239 -----NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAP 293
++VS ++QFV FL L Y Q LY+ +S ++ HL+ LLRCL+ P
Sbjct: 241 FGYDDELYVSG------QQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNP 294
Query: 294 LETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTL 353
L T + L++ D++ LS PS+ QLKEL L I + + EPL LLE+ ATL+ L
Sbjct: 295 LGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEIL 354
Query: 354 DLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPA 413
L+DC I DSQL +LPALSRCSQL+TF F GN S AL++LL HT GLSKL LELYPA
Sbjct: 355 TLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPA 414
Query: 414 PLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCG 460
PLE D +G + W + + AELM TLR++RQPK I F +PCP CG
Sbjct: 415 PLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,336,116
Number of Sequences: 37866
Number of extensions: 801136
Number of successful extensions: 2569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2403
Number of HSP's gapped (non-prelim): 125
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.