Guide to the Human Genome
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Search of human proteins with 124248546

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|124248546 HHIP-like 2 [Homo sapiens]
         (724 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|124248546 HHIP-like 2 [Homo sapiens]                              1515   0.0  
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]             795   0.0  
gi|187936953 HHIP-like protein 1 isoform b [Homo sapiens]             760   0.0  
gi|20143973 hedgehog-interacting protein [Homo sapiens]               270   3e-72
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]            36   0.14 
gi|6912246 CD3E antigen, epsilon polypeptide associated protein ...    35   0.19 
gi|14719402 homolog of yeast ribosome biogenesis regulatory prot...    34   0.55 
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ...    34   0.55 
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ...    34   0.55 
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ...    34   0.55 
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            34   0.55 
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        34   0.55 
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ...    32   1.6  
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ...    32   1.6  
gi|154350220 DNA polymerase iota [Homo sapiens]                        32   2.1  
gi|27734897 hypothetical protein LOC203111 [Homo sapiens]              32   2.1  
gi|33188443 microfilament and actin filament cross-linker protei...    32   2.7  
gi|33188445 microfilament and actin filament cross-linker protei...    32   2.7  
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ...    32   2.7  
gi|145580626 E2F transcription factor 7 [Homo sapiens]                 32   2.7  
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]             32   2.7  
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]             32   2.7  
gi|239755394 PREDICTED: hypothetical protein [Homo sapiens]            31   3.5  
gi|239744215 PREDICTED: hypothetical protein [Homo sapiens]            31   3.5  
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               31   4.6  
gi|60097902 filaggrin [Homo sapiens]                                   30   6.0  
gi|224809302 xeroderma pigmentosum, complementation group C isof...    30   6.0  
gi|224809295 xeroderma pigmentosum, complementation group C isof...    30   6.0  

>gi|124248546 HHIP-like 2 [Homo sapiens]
          Length = 724

 Score = 1515 bits (3922), Expect = 0.0
 Identities = 724/724 (100%), Positives = 724/724 (100%)

Query: 1   MLRTSTPNLCGGLHCRAPWLSSGILCLCLIFLLGQVGLLQGHPQCLDYGPPFQPPLHLEF 60
           MLRTSTPNLCGGLHCRAPWLSSGILCLCLIFLLGQVGLLQGHPQCLDYGPPFQPPLHLEF
Sbjct: 1   MLRTSTPNLCGGLHCRAPWLSSGILCLCLIFLLGQVGLLQGHPQCLDYGPPFQPPLHLEF 60

Query: 61  CSDYESFGCCDQHKDRRIAARYWDIMEYFDLKRHELCGDYIKDILCQECSPYAAHLYDAE 120
           CSDYESFGCCDQHKDRRIAARYWDIMEYFDLKRHELCGDYIKDILCQECSPYAAHLYDAE
Sbjct: 61  CSDYESFGCCDQHKDRRIAARYWDIMEYFDLKRHELCGDYIKDILCQECSPYAAHLYDAE 120

Query: 121 NTQTPLRNLPGLCSDYCSAFHSNCHSAISLLTNDRGLQESHGRDGTRFCHLLDLPDKDYC 180
           NTQTPLRNLPGLCSDYCSAFHSNCHSAISLLTNDRGLQESHGRDGTRFCHLLDLPDKDYC
Sbjct: 121 NTQTPLRNLPGLCSDYCSAFHSNCHSAISLLTNDRGLQESHGRDGTRFCHLLDLPDKDYC 180

Query: 181 FPNVLRNDYLNRHLGMVAQDPQGCLQLCLSEVANGLRNPVSMVHAGDGTHRFFVAEQVGV 240
           FPNVLRNDYLNRHLGMVAQDPQGCLQLCLSEVANGLRNPVSMVHAGDGTHRFFVAEQVGV
Sbjct: 181 FPNVLRNDYLNRHLGMVAQDPQGCLQLCLSEVANGLRNPVSMVHAGDGTHRFFVAEQVGV 240

Query: 241 VWVYLPDGSRLEQPFLDLKNIVLTTPWIGDERGFLGLAFHPKFRHNRKFYIYYSCLDKKK 300
           VWVYLPDGSRLEQPFLDLKNIVLTTPWIGDERGFLGLAFHPKFRHNRKFYIYYSCLDKKK
Sbjct: 241 VWVYLPDGSRLEQPFLDLKNIVLTTPWIGDERGFLGLAFHPKFRHNRKFYIYYSCLDKKK 300

Query: 301 VEKIRISEMKVSRADPNKADLKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQA 360
           VEKIRISEMKVSRADPNKADLKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQA
Sbjct: 301 VEKIRISEMKVSRADPNKADLKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQA 360

Query: 361 GDPFGLFGNAQNKSSLLGKVLRIDVNRAGSHGKRYRVPSDNPFVSEPGAHPAIYAYGIRN 420
           GDPFGLFGNAQNKSSLLGKVLRIDVNRAGSHGKRYRVPSDNPFVSEPGAHPAIYAYGIRN
Sbjct: 361 GDPFGLFGNAQNKSSLLGKVLRIDVNRAGSHGKRYRVPSDNPFVSEPGAHPAIYAYGIRN 420

Query: 421 MWRCAVDRGDPITRQGRGRIFCGDVGQNRFEEVDLILKGGNYGWRAKEGFACYDKKLCHN 480
           MWRCAVDRGDPITRQGRGRIFCGDVGQNRFEEVDLILKGGNYGWRAKEGFACYDKKLCHN
Sbjct: 421 MWRCAVDRGDPITRQGRGRIFCGDVGQNRFEEVDLILKGGNYGWRAKEGFACYDKKLCHN 480

Query: 481 ASLDDVLPIYAYGHAVGKSVTGGYVYRGCESPNLNGLYIFGDFMSGRLMALQEDRKNKKW 540
           ASLDDVLPIYAYGHAVGKSVTGGYVYRGCESPNLNGLYIFGDFMSGRLMALQEDRKNKKW
Sbjct: 481 ASLDDVLPIYAYGHAVGKSVTGGYVYRGCESPNLNGLYIFGDFMSGRLMALQEDRKNKKW 540

Query: 541 KKQDLCLGSTTSCAFPGLISTHSKFIISFAEDEAGELYFLATSYPSAYAPRGSIYKFVDP 600
           KKQDLCLGSTTSCAFPGLISTHSKFIISFAEDEAGELYFLATSYPSAYAPRGSIYKFVDP
Sbjct: 541 KKQDLCLGSTTSCAFPGLISTHSKFIISFAEDEAGELYFLATSYPSAYAPRGSIYKFVDP 600

Query: 601 SRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGL 660
           SRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGL
Sbjct: 601 SRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGL 660

Query: 661 SEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAG 720
           SEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAG
Sbjct: 661 SEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAG 720

Query: 721 RSLP 724
           RSLP
Sbjct: 721 RSLP 724


>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
          Length = 782

 Score =  795 bits (2054), Expect = 0.0
 Identities = 386/676 (57%), Positives = 473/676 (69%), Gaps = 14/676 (2%)

Query: 42  HPQCLDYGPPFQPPLHLEFCSDYESFGCCDQHKDRRIAARYWDIMEYFDLKRHELCGDYI 101
           HPQCLD+ PPF+P   L  C+ Y  FGCCD+ +D  +  R+W +    D      C  Y 
Sbjct: 20  HPQCLDFRPPFRPTQPLRLCAQYSDFGCCDEGRDAELTRRFWALASRVDAAEWAACAGYA 79

Query: 102 KDILCQECSPYAAHLYDAENTQTPLRNLPGLCSDYCSAFHSNCHSAISLLTNDRGLQESH 161
           +D+LCQECSPYAAHLYDAE+  TPLR +PGLC DYC      C      L+ D+ L    
Sbjct: 80  RDLLCQECSPYAAHLYDAEDPFTPLRTVPGLCQDYCLDMWHKCRGLFRHLSTDQELWALE 139

Query: 162 GRDGTRFCHLLDLPDKDYCFPNVLRNDYLNRHLGMVAQDPQGCLQLCLSEVANGLRNPVS 221
           G +  RFC  L L D DYCFP +L N  LN +LG V  D +GCLQLCL EVANGLRNPV+
Sbjct: 140 G-NLARFCRYLSLDDTDYCFPYLLVNKNLNSNLGHVVADAKGCLQLCLEEVANGLRNPVA 198

Query: 222 MVHAGDGTHRFFVAEQVGVVWVYLPDGSRLEQPFLDLKNIVLTTPWIGDERGFLGLAFHP 281
           MVHA DGTHRFFVAEQVG+VW YLPD SRL +PFL++  +VLT+PW GDERGFLG+AFHP
Sbjct: 199 MVHARDGTHRFFVAEQVGLVWAYLPDRSRLGKPFLNISRVVLTSPWEGDERGFLGIAFHP 258

Query: 282 KFRHNRKFYIYYSCLDKKKVEKIRISEMKVSRADPNKADLKSERVILEIEEPASNHNGGQ 341
            F+HNR+ Y+YYS +  +  E IRISE +VS  D N  D  SER+ILE++EPASNHNGGQ
Sbjct: 259 SFQHNRRLYVYYS-VGIRSSEWIRISEFRVSEDDENAVDHSSERIILEVKEPASNHNGGQ 317

Query: 342 LLFGLDGYMYIFTGDGGQAGDPFGLFGNAQNKSSLLGKVLRIDVNRAGSHGKRYRVPSDN 401
           LLFG DGY+YIFTGDGG AGDPFG FGNAQNKS+LLGKVLRIDV+R    G  Y +P DN
Sbjct: 318 LLFGDDGYLYIFTGDGGMAGDPFGTFGNAQNKSALLGKVLRIDVDRK-ERGLPYGIPPDN 376

Query: 402 PFVSEPGAHPAIYAYGIRNMWRCAVDRGDPITRQGRGRIFCGDVGQNRFEEVDLILKGGN 461
           PFV +P A P +YA G+RNMWRC+ DRGDP +  GRGR+FCGDVGQN+FEEVD++ +GGN
Sbjct: 377 PFVGDPAAQPEVYALGVRNMWRCSFDRGDPSSGTGRGRLFCGDVGQNKFEEVDVVERGGN 436

Query: 462 YGWRAKEGFACYDKKLCHNASLDDVLPIYAYGHAVGKSVTGGYVYRGCESPNLNGLYIFG 521
           YGWRA+EGF CYD+ LC N SL+D+LPI+AY H VGKSVTGGYVYRGCE PNLNGLYIFG
Sbjct: 437 YGWRAREGFECYDRSLCANTSLNDLLPIFAYPHTVGKSVTGGYVYRGCEYPNLNGLYIFG 496

Query: 522 DFMSGRLMALQEDRKNKKWKKQDLCLGSTTSCAFPGLISTHSKFIISFAEDEAGELYFLA 581
           DFMSGRLM+LQE+    +W+  ++C+G   +C FPGLI+ +  +IISF EDEAGELYF++
Sbjct: 497 DFMSGRLMSLQENPGTGQWQYSEICMGHGQTCEFPGLINNYYPYIISFGEDEAGELYFMS 556

Query: 582 TSYPSAYAPRGSIYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSE 641
           T  PSA APRG +YK +D SRRAPPGKC+ +P  V+ +S+ IPF P  K  +   +    
Sbjct: 557 TGEPSATAPRGVVYKIIDASRRAPPGKCQIQPAQVKIRSRLIPFVPKEK-FIPKTRSTPR 615

Query: 642 KAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQGK--- 698
             AR  + A     P    +    + + A PT    + RG G +++ R+    R  +   
Sbjct: 616 PTARAPTRAPRRGRPT--AAPPAPTPRPARPTQQPGSRRG-GGRRRGRLNSASRAFRDGE 672

Query: 699 ----RRKSLKSHSGRM 710
               R   L S SGR+
Sbjct: 673 VRLVRPAGLSSGSGRV 688


>gi|187936953 HHIP-like protein 1 isoform b [Homo sapiens]
          Length = 608

 Score =  760 bits (1963), Expect = 0.0
 Identities = 359/578 (62%), Positives = 428/578 (74%), Gaps = 10/578 (1%)

Query: 42  HPQCLDYGPPFQPPLHLEFCSDYESFGCCDQHKDRRIAARYWDIMEYFDLKRHELCGDYI 101
           HPQCLD+ PPF+P   L  C+ Y  FGCCD+ +D  +  R+W +    D      C  Y 
Sbjct: 20  HPQCLDFRPPFRPTQPLRLCAQYSDFGCCDEGRDAELTRRFWALASRVDAAEWAACAGYA 79

Query: 102 KDILCQECSPYAAHLYDAENTQTPLRNLPGLCSDYCSAFHSNCHSAISLLTNDRGLQESH 161
           +D+LCQECSPYAAHLYDAE+  TPLR +PGLC DYC      C      L+ D+ L    
Sbjct: 80  RDLLCQECSPYAAHLYDAEDPFTPLRTVPGLCQDYCLDMWHKCRGLFRHLSTDQELWALE 139

Query: 162 GRDGTRFCHLLDLPDKDYCFPNVLRNDYLNRHLGMVAQDPQGCLQLCLSEVANGLRNPVS 221
           G +  RFC  L L D DYCFP +L N  LN +LG V  D +GCLQLCL EVANGLRNPV+
Sbjct: 140 G-NLARFCRYLSLDDTDYCFPYLLVNKNLNSNLGHVVADAKGCLQLCLEEVANGLRNPVA 198

Query: 222 MVHAGDGTHRFFVAEQVGVVWVYLPDGSRLEQPFLDLKNIVLTTPWIGDERGFLGLAFHP 281
           MVHA DGTHRFFVAEQVG+VW YLPD SRL +PFL++  +VLT+PW GDERGFLG+AFHP
Sbjct: 199 MVHARDGTHRFFVAEQVGLVWAYLPDRSRLGKPFLNISRVVLTSPWEGDERGFLGIAFHP 258

Query: 282 KFRHNRKFYIYYSCLDKKKVEKIRISEMKVSRADPNKADLKSERVILEIEEPASNHNGGQ 341
            F+HNR+ Y+YYS +  +  E IRISE +VS  D N  D  SER+ILE++EPASNHNGGQ
Sbjct: 259 SFQHNRRLYVYYS-VGIRSSEWIRISEFRVSEDDENAVDHSSERIILEVKEPASNHNGGQ 317

Query: 342 LLFGLDGYMYIFTGDGGQAGDPFGLFGNAQNKSSLLGKVLRIDVNRAGSHGKRYRVPSDN 401
           LLFG DGY+YIFTGDGG AGDPFG FGNAQNKS+LLGKVLRIDV+R    G  Y +P DN
Sbjct: 318 LLFGDDGYLYIFTGDGGMAGDPFGTFGNAQNKSALLGKVLRIDVDRK-ERGLPYGIPPDN 376

Query: 402 PFVSEPGAHPAIYAYGIRNMWRCAVDRGDPITRQGRGRIFCGDVGQNRFEEVDLILKGGN 461
           PFV +P A P +YA G+RNMWRC+ DRGDP +  GRGR+FCGDVGQN+FEEVD++ +GGN
Sbjct: 377 PFVGDPAAQPEVYALGVRNMWRCSFDRGDPSSGTGRGRLFCGDVGQNKFEEVDVVERGGN 436

Query: 462 YGWRAKEGFACYDKKLCHNASLDDVLPIYAYGHAVGKSVTGGYVYRGCESPNLNGLYIFG 521
           YGWRA+EGF CYD+ LC N SL+D+LPI+AY H VGKSVTGGYVYRGCE PNLNGLYIFG
Sbjct: 437 YGWRAREGFECYDRSLCANTSLNDLLPIFAYPHTVGKSVTGGYVYRGCEYPNLNGLYIFG 496

Query: 522 DFMSGRLMALQEDRKNKKWKKQDLCLGSTTSCAFPGLISTHSKFIISFAEDEAGELYFLA 581
           DFMSGRLM+LQE+    +W+  ++C+G   +C FPGLI+ +  +IISF EDEAGELYF++
Sbjct: 497 DFMSGRLMSLQENPGTGQWQYSEICMGHGQTCEFPGLINNYYPYIISFGEDEAGELYFMS 556

Query: 582 TSYPSAYAPRGSIYKFVDPS----RRAPPGKCKYKPVP 615
           T  PSA APRG +YK +D S    R A PG   Y P P
Sbjct: 557 TGEPSATAPRGVVYKIIDASSCKARSAMPG---YVPAP 591


>gi|20143973 hedgehog-interacting protein [Homo sapiens]
          Length = 700

 Score =  270 bits (691), Expect = 3e-72
 Identities = 180/552 (32%), Positives = 269/552 (48%), Gaps = 65/552 (11%)

Query: 89  FDLKRHELCGDYIKDILCQECSPYAAHLYDAENTQTPLRNL--PGLCSDYCSAFHSNCHS 146
           F +  +  CG  +++I C  CSP++  L+ +   +   R+L  P LC DYC  F   C  
Sbjct: 95  FSVTNNTECGKLLEEIKCALCSPHSQSLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRG 154

Query: 147 AISLLTNDRGLQESHGRDGTRFCHLLDLPDKDYCFPNVLR-------NDYLNRHLG---- 195
            I       G  ++   +   FC      D   CFP+  R       ++YL++       
Sbjct: 155 HIP------GFLQTTADE---FCFYYARKDGGLCFPDFPRKQVRGPASNYLDQMEEYDKV 205

Query: 196 --MVAQDPQGCLQLCLSEVANGLRNPVSMVHAGDGTHRFFVAEQVGVVWVYLPDGSRLEQ 253
             +  +    C   C+ EV +GLR PV  +H+GDG+ R F+ E+ G V +  P+G   ++
Sbjct: 206 EEISRKHKHNCF--CIQEVVSGLRQPVGALHSGDGSQRLFILEKEGYVKILTPEGEIFKE 263

Query: 254 PFLDLKNIVLTTPWIGDERGFLGLAFHPKFRHNRKFYIYYSCLDKKKV-----EKIRISE 308
           P+LD+  +V +    GDERG L LAFHP ++ N K Y+ Y+   ++         +R+ E
Sbjct: 264 PYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLYVSYTTNQERWAIGPHDHILRVVE 323

Query: 309 MKVSRADPNKADLKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQAGDPFGLFG 368
             VSR +P++ DL++ RV LE+ E    H GGQLLFG DG++YI  GDG    D      
Sbjct: 324 YTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFGPDGFLYIILGDGMITLDD---ME 380

Query: 369 NAQNKSSLLGKVLRIDVNRAGSHGKRYRVPSDNPFVSEPGAHPAIYAYGIRNMWRCAVDR 428
                S   G VLR+DV+        Y +P  NP  +     P ++A+G+ +  RCAVDR
Sbjct: 381 EMDGLSDFTGSVLRLDVD-TDMCNVPYSIPRSNPHFNSTNQPPEVFAHGLHDPGRCAVDR 439

Query: 429 GDPITRQGRGRIFCGDV-GQNRFE-EVDLILKGGNYGWRAKEGFACYDKKLCHNASLDDV 486
             P        I C D  G+NR    +  I+KG +Y                   S   +
Sbjct: 440 -HPTDININLTILCSDSNGKNRSSARILQIIKGKDY------------------ESEPSL 480

Query: 487 LPIYAYGHAVGKSVTGGYVYRGCESPNLNGLYIFGDFMSGRLMALQEDRKNKKWKKQDLC 546
           L    + +     + GG+VYRGC+S  L G Y+FGD  +G  + LQ+    K+W+++ LC
Sbjct: 481 LEFKPFSNG---PLVGGFVYRGCQSERLYGSYVFGD-RNGNFLTLQQSPVTKQWQEKPLC 536

Query: 547 LGSTTSCAFPGLISTHSKFIISFAEDEAGELYFLATSYPSAYAPRGSIYKFVDPSRRAPP 606
           LG++ SC   G  S H   I+ F EDE GE+Y L++S        G +YK VDP R   P
Sbjct: 537 LGTSGSCR--GYFSGH---ILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMP 591

Query: 607 GKCKYKPVPVRT 618
            +C+    P +T
Sbjct: 592 EECRATVQPAQT 603


>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 594 IYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLA 653
           +Y+  +  RRA   +C+ +   +  + KR  F PL+             AA  +++A  A
Sbjct: 150 LYEAYEAERRAKLQQCRAERERIMREEKRRLFTPLS------------PAAAAAAAAAAA 197

Query: 654 SGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGP---HVRQGKRRKSLKSHSGRM 710
           S P+ G S   SS  L +  + +   +   +   AR  P     R G++  SL S S R 
Sbjct: 198 SAPSAGSSSSCSSASLPASPAPRAARKASPSPSSARTQPPPAGSRTGRKSHSLDSLS-RR 256

Query: 711 RPSAEQKRAGRS 722
           R  A    +G S
Sbjct: 257 REGALSSESGAS 268


>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 594 IYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLA 653
           +Y+  +  RRA   +C+ +   +  + KR  F PL+             AA  +++A  A
Sbjct: 150 LYEAYEAERRAKLQQCRAERERIMREEKRRLFTPLS------------PAAAAAAAAAAA 197

Query: 654 SGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGP---HVRQGKRRKSLKSHSGRM 710
           S P+ G S   SS  L +  + +   +   +   AR  P     R G++  SL S S R 
Sbjct: 198 SAPSAGSSSSCSSASLPASPAPRAARKASPSPSSARTQPPPAGSRTGRKSHSLDSLS-RR 256

Query: 711 RPSAEQKRAGRS 722
           R  A    +G S
Sbjct: 257 REGALSSESGAS 268


>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 625

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 594 IYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLA 653
           +Y+  +  RRA   +C+ +   +  + KR  F PL+          S  +A  SSS + A
Sbjct: 150 LYEAYEAERRAKLQQCRAERDRIMREEKRRLFTPLSPAAAAAAAAASAPSAGSSSSCSSA 209

Query: 654 SGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPS 713
           S PA   + + + K   SP+S++      G+          R G++  SL S S R R  
Sbjct: 210 SLPASP-APRAARKASPSPSSARTQPPPAGS----------RTGRKSHSLDSLS-RRREG 257

Query: 714 AEQKRAGRS 722
           A    +G S
Sbjct: 258 ALSSESGAS 266


>gi|6912246 CD3E antigen, epsilon polypeptide associated protein
           [Homo sapiens]
          Length = 510

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 8/100 (8%)

Query: 590 PRGSIYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSS 649
           P G ++      R+ P GK  ++P     K ++I   PL  TVL   K+      RK   
Sbjct: 241 PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKK------RKRQK 294

Query: 650 ATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKAR 689
            T    P +G++ +   +    P      L  P TKK+ +
Sbjct: 295 GTEGMEPEEGVTVESQPQVKVEPLEEAIPL--PPTKKRKK 332


>gi|14719402 homolog of yeast ribosome biogenesis regulatory protein
           RRS1 [Homo sapiens]
          Length = 365

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 10/116 (8%)

Query: 617 RTKSKRIPFRPL-------AKTVLDLLKEQSEKAARKS-SSATLASGPAQGLSEKGSSKK 668
           R   K+  F+PL        K  L+LL+  + K  +   + AT      +   E    +K
Sbjct: 246 RGSGKKRKFQPLFGDFAAEKKNQLELLRVMNSKKPQLDVTRATNKQMREEDQEEAAKRRK 305

Query: 669 LASPTSSKNTLRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAGRSLP 724
           ++     K   +GPG K+K   GP  + GKR+  L        P    KR G   P
Sbjct: 306 MSQKGKRKGGRQGPGGKRKG--GPPSQGGKRKGGLGGKMNSGPPGLGGKRKGGQRP 359


>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
           sapiens]
          Length = 355

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 24/135 (17%)

Query: 581 ATSYPSAY--APRGS--IYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLL 636
           A S P AY  APRGS   Y     + RA  G  KY        S R+P RP   +     
Sbjct: 106 ADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKYNSAH---SSSRVP-RPRLPS----- 156

Query: 637 KEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQ 696
                   R+ +S  L  GP    + +G    L   ++   T RGP   ++   GPH   
Sbjct: 157 -------QRRGASCGLGPGPESRAARQG----LGGRSARARTRRGPHRTRRPEPGPHHTG 205

Query: 697 GKRRKSLKSHSGRMR 711
            ++   L    GR R
Sbjct: 206 ARQAGPLPGTRGRTR 220


>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
           sapiens]
          Length = 355

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 24/135 (17%)

Query: 581 ATSYPSAY--APRGS--IYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLL 636
           A S P AY  APRGS   Y     + RA  G  KY        S R+P RP   +     
Sbjct: 106 ADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKYNSAH---SSSRVP-RPRLPS----- 156

Query: 637 KEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQ 696
                   R+ +S  L  GP    + +G    L   ++   T RGP   ++   GPH   
Sbjct: 157 -------QRRGASCGLGPGPESRAARQG----LGGRSARARTRRGPHRTRRPEPGPHHTG 205

Query: 697 GKRRKSLKSHSGRMR 711
            ++   L    GR R
Sbjct: 206 ARQAGPLPGTRGRTR 220


>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
           sapiens]
          Length = 355

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 24/135 (17%)

Query: 581 ATSYPSAY--APRGS--IYKFVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLL 636
           A S P AY  APRGS   Y     + RA  G  KY        S R+P RP   +     
Sbjct: 106 ADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKYNSAH---SSSRVP-RPRLPS----- 156

Query: 637 KEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQ 696
                   R+ +S  L  GP    + +G    L   ++   T RGP   ++   GPH   
Sbjct: 157 -------QRRGASCGLGPGPESRAARQG----LGGRSARARTRRGPHRTRRPEPGPHHTG 205

Query: 697 GKRRKSLKSHSGRMR 711
            ++   L    GR R
Sbjct: 206 ARQAGPLPGTRGRTR 220


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 19/60 (31%), Positives = 29/60 (48%)

Query: 378  GKVLRIDVNRAGSHGKRYRVPSDNPFVSEPGAHPAIYAYGIRNMWRCAVDRGDPITRQGR 437
            G+V+ ID N     GK  RVP   PF        A+   G+  ++R + ++   I R+GR
Sbjct: 2348 GEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGR 2407


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 16/120 (13%)

Query: 600 PSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQG 659
           P+R   P K   K +P  + S+  P  P           Q  K +R +SS+  +  PA  
Sbjct: 399 PTRDRSPPKSPEK-LPQSSSSESSPPSP-----------QPTKVSRHASSSPESPKPAPA 446

Query: 660 LSEKGSSKKLASPTSSKNTLRGPGTKKKARVG-PHVRQGKRRKSLKSHSGRMRPSAEQKR 718
               GS ++++S  +SKN   G   + K+    P  R G+ R    +  GR R     KR
Sbjct: 447 ---PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKR 503



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 6/128 (4%)

Query: 601 SRRAPPGKCKYKPVPVRTKSK-RIPFR---PLAKTVLDLLKEQSEKAARKSSSATLAS-G 655
           SR A  G+   +    R +S+ R P R     ++T             R+S S T A  G
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRG 613

Query: 656 PAQGLSEKGSSKKLASPTSSKNTLRGPGTKK-KARVGPHVRQGKRRKSLKSHSGRMRPSA 714
            ++  +      +  SP   ++  R P  +  ++R     R+G+ R    +  GR R   
Sbjct: 614 RSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRT 673

Query: 715 EQKRAGRS 722
             +R+GRS
Sbjct: 674 PARRSGRS 681



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 25/119 (21%), Positives = 47/119 (39%), Gaps = 1/119 (0%)

Query: 603  RAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGLSE 662
            R PP +   +  P  T+  R+  R  + +     + ++    R+S S + +  PA+    
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS-SPEPAEKSRS 1741

Query: 663  KGSSKKLASPTSSKNTLRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAGR 721
                +  +SP +   + RG     K R     R   RR+  ++   R R  + Q  + R
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800


>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 27/166 (16%)

Query: 577 LYFLATSYPSAYAPRGSIYKFVDPSRRA---------PPGKCKYKP--VPVRTKSKRIPF 625
           +Y     Y S   P+G  +   +   +A         PP +   KP   P   K+K IP 
Sbjct: 152 VYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIP- 210

Query: 626 RPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSK-KLASPTSSKNTLRGPGT 684
               + V +  K++ +K   K      A       S    SK K + PTS  + +     
Sbjct: 211 --ALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEP 268

Query: 685 --------KKKARVG----PHVRQGKRRKSLKSHSGRMRPSAEQKR 718
                   KK+ RV     P VR GKR++S    +  + P ++ K+
Sbjct: 269 QKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKK 314


>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 27/166 (16%)

Query: 577 LYFLATSYPSAYAPRGSIYKFVDPSRRA---------PPGKCKYKP--VPVRTKSKRIPF 625
           +Y     Y S   P+G  +   +   +A         PP +   KP   P   K+K IP 
Sbjct: 152 VYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIP- 210

Query: 626 RPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSK-KLASPTSSKNTLRGPGT 684
               + V +  K++ +K   K      A       S    SK K + PTS  + +     
Sbjct: 211 --ALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEP 268

Query: 685 --------KKKARVG----PHVRQGKRRKSLKSHSGRMRPSAEQKR 718
                   KK+ RV     P VR GKR++S    +  + P ++ K+
Sbjct: 269 QKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKK 314


>gi|154350220 DNA polymerase iota [Homo sapiens]
          Length = 740

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 6/70 (8%)

Query: 646 KSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARV-----GPH-VRQGKR 699
           + +S  + SGP Q  SE+ S KK +S   +KN +         RV      PH VR   R
Sbjct: 313 EDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIR 372

Query: 700 RKSLKSHSGR 709
           R S + H GR
Sbjct: 373 RYSSEKHYGR 382


>gi|27734897 hypothetical protein LOC203111 [Homo sapiens]
          Length = 374

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 16/140 (11%)

Query: 552 SCAFPGLISTHSKFIISFAEDEAGELYFLATSYPSAYAPRGSIYKFVDPSRRAPPGKCKY 611
           S  FP + S        F+  E  E  F A   P A     ++   V    R P  K K 
Sbjct: 14  SSRFPSVTSNEH-----FSTAEESESCF-AQPKPHALGRESTVDGNVQRESRPPLQKLKV 67

Query: 612 KPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSKKLAS 671
              P     K +  +PLAK V         + A   S +T  + P +GL E G  +    
Sbjct: 68  SAEPTANGVKPLQEQPLAKDV------APGRDATDQSGSTEKTQPGEGLEESGPPQ---- 117

Query: 672 PTSSKNTLRGPGTKKKARVG 691
           P   ++     G KK A  G
Sbjct: 118 PGGKEDAPAAEGKKKDAGAG 137


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 36/110 (32%), Positives = 48/110 (43%), Gaps = 13/110 (11%)

Query: 582  TSYPSAYAPRGSIYKFVDPSRRAP-PGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQS 640
            TS  S+ A  G+     DP + A  PG         R  S+R        +  DLL+ QS
Sbjct: 5837 TSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRR----GSDASDFDLLETQS 5892

Query: 641  EKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTL----RGPGTKK 686
              A   +S ++ A G  QG S +G +K    PT SK T     R PG K+
Sbjct: 5893 --ACSDTSESSAAGG--QGNSRRGLNKPSKIPTMSKKTTTASPRTPGPKR 5938


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 36/110 (32%), Positives = 48/110 (43%), Gaps = 13/110 (11%)

Query: 582  TSYPSAYAPRGSIYKFVDPSRRAP-PGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQS 640
            TS  S+ A  G+     DP + A  PG         R  S+R        +  DLL+ QS
Sbjct: 5329 TSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRR----GSDASDFDLLETQS 5384

Query: 641  EKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTL----RGPGTKK 686
              A   +S ++ A G  QG S +G +K    PT SK T     R PG K+
Sbjct: 5385 --ACSDTSESSAAGG--QGNSRRGLNKPSKIPTMSKKTTTASPRTPGPKR 5430


>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
           sapiens]
          Length = 709

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 641 EKAARK-SSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPG 683
           E+AAR  S SATL S P  G  ++ SS   +S  +  N+  GPG
Sbjct: 455 EEAARALSGSATLVSSPKYGSDDECSSASASSAGAGSNSGAGPG 498


>gi|145580626 E2F transcription factor 7 [Homo sapiens]
          Length = 911

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 21/81 (25%), Positives = 37/81 (45%)

Query: 597 FVDPSRRAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGP 656
           FVD SR AP    K +P+ +  + K  P R     V  + ++Q+E     ++   L S  
Sbjct: 35  FVDRSRMAPKTPIKNEPIDLSKQKKFTPERNPITPVKFVDRQQAEPWTPTANLKMLISAA 94

Query: 657 AQGLSEKGSSKKLASPTSSKN 677
           +  + ++   K L  P  +K+
Sbjct: 95  SPDIRDREKKKGLFRPIENKD 115


>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
          Length = 338

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 11/91 (12%)

Query: 629 AKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKA 688
           A T  +  K+++ +  R SSS           S   SS   +S +SS ++    G KK+ 
Sbjct: 161 ASTSQERSKQKARRRTRSSSS-----------SSSSSSSSSSSSSSSSSSSSSDGRKKRG 209

Query: 689 RVGPHVRQGKRRKSLKSHSGRMRPSAEQKRA 719
           +     R+ K+++      G+ +  A+Q  A
Sbjct: 210 KYKDKRRKKKKKRKKLKKKGKEKAEAQQVEA 240


>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
          Length = 341

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 11/91 (12%)

Query: 629 AKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKA 688
           A T  +  K+++ +  R SSS           S   SS   +S +SS ++    G KK+ 
Sbjct: 161 ASTSQERSKQKARRRTRSSSS-----------SSSSSSSSSSSSSSSSSSSSSDGRKKRG 209

Query: 689 RVGPHVRQGKRRKSLKSHSGRMRPSAEQKRA 719
           +     R+ K+++      G+ +  A+Q  A
Sbjct: 210 KYKDKRRKKKKKRKKLKKKGKEKAEAQQVEA 240


>gi|239755394 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 217

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 24/103 (23%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 619 KSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNT 678
           + ++ P R L     +  +E+ E+  R+        G  QG ++   ++    P ++   
Sbjct: 52  RQRKSPLRTLRSNQEEQEEEEDEQNGRRHQP-----GRKQGRAQARPARSPLRPAATACK 106

Query: 679 LRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAGR 721
               G +KK R G    + +R  S    SGR +PS  ++R+G+
Sbjct: 107 GDDRGERKKGRRGNPGTRSRRITSSLWASGRPKPSQLRERSGK 149


>gi|239744215 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 217

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 24/103 (23%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 619 KSKRIPFRPLAKTVLDLLKEQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNT 678
           + ++ P R L     +  +E+ E+  R+        G  QG ++   ++    P ++   
Sbjct: 52  RQRKSPLRTLRSNQEEQEEEEDEQNGRRHQP-----GRKQGRAQARPARSPLRPAATACK 106

Query: 679 LRGPGTKKKARVGPHVRQGKRRKSLKSHSGRMRPSAEQKRAGR 721
               G +KK R G    + +R  S    SGR +PS  ++R+G+
Sbjct: 107 GDDRGERKKGRRGNPGTRSRRITSSLWASGRPKPSQLRERSGK 149


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 35/137 (25%), Positives = 56/137 (40%), Gaps = 18/137 (13%)

Query: 603 RAPPGKCKYKPVPVRTKSKRIPFRPLAKTVLDLLKEQSEKAARKSSS------ATLASGP 656
           R PP   +  P+P  T S + P   LA+T   +    S+ A+ ++S+        L+S P
Sbjct: 434 RPPPPSTR--PLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSP 491

Query: 657 AQGLSEKGSSKKLAS---PTSSKNTLR------GPGTKKKARVGPHVRQGKRRKSLKSHS 707
           A       S++  A+   PTS  +T R       PG+       P   +  ++   KS S
Sbjct: 492 APTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKS-S 550

Query: 708 GRMRPSAEQKRAGRSLP 724
            R        +A R +P
Sbjct: 551 PRKPVPLRPGKAARDVP 567


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 5/72 (6%)

Query: 638  EQSEKAARKSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRG-PGTKKKARVGPHVRQ 696
            EQSE A  ++ ++T     +     + SS+  AS    ++T+RG PG+ ++ R G H  Q
Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ-EGQDTIRGHPGSSRRGRQGSHYEQ 3452

Query: 697  GKRRKSLKSHSG 708
               R     HSG
Sbjct: 3453 SVDR---SGHSG 3461


>gi|224809302 xeroderma pigmentosum, complementation group C isoform
           2 [Homo sapiens]
          Length = 903

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 5/56 (8%)

Query: 657 AQGLSEKGSSKKLASPTSSKNTLRGPGTK--KKARVGPHVRQGK--RRKSLKSHSG 708
           A+G   KG  KK + P+SS+    GPG K  K  +  PH R+ +   R S K  SG
Sbjct: 344 AKGKRNKGGRKKRSKPSSSEED-EGPGDKQEKATQRRPHGRERRVASRVSYKEESG 398


>gi|224809295 xeroderma pigmentosum, complementation group C isoform
           1 [Homo sapiens]
          Length = 940

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 5/56 (8%)

Query: 657 AQGLSEKGSSKKLASPTSSKNTLRGPGTK--KKARVGPHVRQGK--RRKSLKSHSG 708
           A+G   KG  KK + P+SS+    GPG K  K  +  PH R+ +   R S K  SG
Sbjct: 381 AKGKRNKGGRKKRSKPSSSEED-EGPGDKQEKATQRRPHGRERRVASRVSYKEESG 435


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,482,887
Number of Sequences: 37866
Number of extensions: 1575702
Number of successful extensions: 3966
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3904
Number of HSP's gapped (non-prelim): 77
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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