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Search of human proteins with 124244056
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124244056 family with sequence similarity 123B [Homo
sapiens]
(1135 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124244056 family with sequence similarity 123B [Homo sapiens] 2331 0.0
gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens] 209 2e-53
gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens] 105 3e-22
gi|157427665 hypothetical protein LOC205147 [Homo sapiens] 79 2e-14
gi|157427663 hypothetical protein LOC205147 [Homo sapiens] 79 2e-14
gi|157427661 hypothetical protein LOC205147 [Homo sapiens] 79 2e-14
gi|157427667 hypothetical protein LOC205147 [Homo sapiens] 79 2e-14
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 55 3e-07
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 55 3e-07
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 54 8e-07
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 52 3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 51 5e-06
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 51 5e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 50 2e-05
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 49 2e-05
gi|215422388 death-domain associated protein isoform a [Homo sap... 49 2e-05
gi|215422366 death-domain associated protein isoform b [Homo sap... 49 2e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens] 49 2e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 3e-05
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 49 4e-05
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 48 5e-05
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 48 6e-05
gi|38372931 brevican isoform 2 [Homo sapiens] 48 6e-05
gi|38372935 brevican isoform 1 [Homo sapiens] 48 6e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 47 8e-05
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 47 8e-05
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 47 1e-04
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ... 47 1e-04
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 47 1e-04
gi|118918413 MICAL C-terminal like [Homo sapiens] 47 1e-04
>gi|124244056 family with sequence similarity 123B [Homo sapiens]
Length = 1135
Score = 2331 bits (6041), Expect = 0.0
Identities = 1135/1135 (100%), Positives = 1135/1135 (100%)
Query: 1 METQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLF 60
METQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLF
Sbjct: 1 METQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLF 60
Query: 61 GGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPL 120
GGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPL
Sbjct: 61 GGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPL 120
Query: 121 PELPCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHR 180
PELPCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHR
Sbjct: 121 PELPCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHR 180
Query: 181 KSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVS 240
KSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVS
Sbjct: 181 KSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVS 240
Query: 241 PTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNP 300
PTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNP
Sbjct: 241 PTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNP 300
Query: 301 PNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSS 360
PNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSS
Sbjct: 301 PNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSS 360
Query: 361 CLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPN 420
CLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPN
Sbjct: 361 CLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPN 420
Query: 421 MNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFE 480
MNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFE
Sbjct: 421 MNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFE 480
Query: 481 DDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGRSSEMFDPFL 540
DDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGRSSEMFDPFL
Sbjct: 481 DDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGRSSEMFDPFL 540
Query: 541 NFEPFLSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEARAREAHAREAHAREAYT 600
NFEPFLSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEARAREAHAREAHAREAYT
Sbjct: 541 NFEPFLSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEARAREAHAREAHAREAYT 600
Query: 601 REAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQVRETQARQEKPVLEYQMRPLG 660
REAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQVRETQARQEKPVLEYQMRPLG
Sbjct: 601 REAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQVRETQARQEKPVLEYQMRPLG 660
Query: 661 PSVMGLAAGVSGTSQISHRGITSAFPTTASSEPDWRDFRPLEKRYEGTCSKKDQSTCLMQ 720
PSVMGLAAGVSGTSQISHRGITSAFPTTASSEPDWRDFRPLEKRYEGTCSKKDQSTCLMQ
Sbjct: 661 PSVMGLAAGVSGTSQISHRGITSAFPTTASSEPDWRDFRPLEKRYEGTCSKKDQSTCLMQ 720
Query: 721 LFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEDPEEEEVEKEGNATVSFSQALVEFTSNG 780
LFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEDPEEEEVEKEGNATVSFSQALVEFTSNG
Sbjct: 721 LFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEDPEEEEVEKEGNATVSFSQALVEFTSNG 780
Query: 781 NLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFHNDEDLAASLEA 840
NLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFHNDEDLAASLEA
Sbjct: 781 NLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFHNDEDLAASLEA 840
Query: 841 FELGYYHKHAFNNYHSRFYQGLPWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAE 900
FELGYYHKHAFNNYHSRFYQGLPWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAE
Sbjct: 841 FELGYYHKHAFNNYHSRFYQGLPWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAE 900
Query: 901 TLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPA 960
TLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPA
Sbjct: 901 TLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPA 960
Query: 961 WAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQL 1020
WAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQL
Sbjct: 961 WAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQL 1020
Query: 1021 ARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGI 1080
ARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGI
Sbjct: 1021 ARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGI 1080
Query: 1081 THGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGASLATSYSSTAMNGNLAK 1135
THGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGASLATSYSSTAMNGNLAK
Sbjct: 1081 THGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGASLATSYSSTAMNGNLAK 1135
>gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]
Length = 671
Score = 209 bits (531), Expect = 2e-53
Identities = 196/603 (32%), Positives = 274/603 (45%), Gaps = 109/603 (18%)
Query: 1 METQKDEA-----AQAKGAAASGSTREQTAEKGAKNK--AAE-------ATEGPTSEPSS 46
MET + ++ GA AS + AE GA AA+ A E P +EP S
Sbjct: 1 METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60
Query: 47 SGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAA--- 103
G++ K A KLF +K T+PS FG ++KG GK S GL +S+THDGL+E
Sbjct: 61 ---GKINKAAFKLFKKRKSGGTMPSIFGV-KNKGDGKSSGPTGLVRSRTHDGLAEVLVLE 116
Query: 104 -------HGPEDVVSEGTGFSLPLPELPCQFPSSQSAHGALETGSRCKT-------SVAG 149
G D S G G P P P ++ G+L + S K+ G
Sbjct: 117 SGRKEEPRGGGD--SGGGGGGRPNPGPP---RAAGPGGGSLASSSVAKSHSFFSLLKKNG 171
Query: 150 ATEKAVAEKFPSMP---KPKKGLKGFFSSIRRHRKSKVTGAEQSEPGAKGPERVRARPHE 206
+E E + K K+GL+G FS +R HRK K AE +E A G + P
Sbjct: 172 RSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLIL--PGS 229
Query: 207 HVSSAPQVPCFEETFQAPRKENANPQDAP--------GPKVSPTPEPSPPATEKMACKDP 258
+S V EET +A R+ QDAP G + P P PA +C++
Sbjct: 230 LTASLECVK--EETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPAR---SCREA 284
Query: 259 E----------KPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVA------------- 295
E + +A +P P ++ + + K V
Sbjct: 285 EGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPA 344
Query: 296 ----GEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMD---SMTDSMASGG 348
V+PP+ P D + L+F DVTSLKSFDSLTGCGDIIA+Q+ + S + G
Sbjct: 345 APDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPG 404
Query: 349 QRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDD---- 404
+ A +K++ +V YQGGGEEMA PD+ D+ +E L + EE+ E +E
Sbjct: 405 KPAL---SKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVA 461
Query: 405 ---DLEYLWETAQMYPRPNMNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQ 461
+ + + ET P+ + S + P+ +P P P+ +QQ
Sbjct: 462 AALETKVVPET----PKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKH---PEKEQQ 514
Query: 462 ESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLPRDSYSGDALYEFY-EPDDSLENSPP 520
E PNSDEGY+DSTTPG E+DS + ++ +PRDSYSGDALY+ Y +PD S P
Sbjct: 515 EGVPNSDEGYWDSTTPGPEEDSSSS---GKKAGIPRDSYSGDALYDLYADPDGSPATLPG 571
Query: 521 GDD 523
G D
Sbjct: 572 GKD 574
>gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]
Length = 552
Score = 105 bits (261), Expect = 3e-22
Identities = 76/208 (36%), Positives = 109/208 (52%), Gaps = 24/208 (11%)
Query: 327 GCGDIIAEQDMD---SMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEE 383
GCGDIIA+Q+ + S + G+ A +K++ +V YQGGGEEMA PD+ D+
Sbjct: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPAL---SKKNPGVVAYQGGGEEMASPDEVDDTYL 317
Query: 384 EEEEVELEEEEEEVKEEEEDD-------DLEYLWETAQMYPRPNMNLGYHPTTSPGHHGY 436
+E L + EE+ E +E + + + ET P+ + S
Sbjct: 318 QEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPET----PKDTRCVEAAKDASSVKRRR 373
Query: 437 MLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLP 496
+ P+ +P P P+ +QQE PNSDEGY+DSTTPG E+DS + ++ +P
Sbjct: 374 LNRIPIEPHPKEEPKH---PEKEQQEGVPNSDEGYWDSTTPGPEEDSSSS---GKKAGIP 427
Query: 497 RDSYSGDALYEFY-EPDDSLENSPPGDD 523
RDSYSGDALY+ Y +PD S P G D
Sbjct: 428 RDSYSGDALYDLYADPDGSPATLPGGKD 455
>gi|157427665 hypothetical protein LOC205147 [Homo sapiens]
Length = 861
Score = 79.3 bits (194), Expect = 2e-14
Identities = 71/229 (31%), Positives = 90/229 (39%), Gaps = 44/229 (19%)
Query: 315 DVTSLKSFDSLTGCGDIIA-EQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMA 373
DV SL+SFDSLTGCG++ A E + S+ + G + QG E++A
Sbjct: 237 DVASLQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLA 296
Query: 374 LPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGH 433
P + E D W++ R P S G
Sbjct: 297 SP-----------------------AQNEASDFTRFWDSVNRSVRQQQRALLGPWLS-GP 332
Query: 434 HGYMLLDPVRSYPGLAPGELL-----------------TPQSDQQESAPNSDEGYYDSTT 476
G GLA L TP+S+Q ES SDEGYYDS +
Sbjct: 333 QGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFS 392
Query: 477 PGFEDDSGEALGL-VRRDCLPRDSYSGDALYE-FYEPDDSLENSPPGDD 523
PG E+D EA PRDSYSGDALYE F++P + P DD
Sbjct: 393 PGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGPLGPSPDDD 441
>gi|157427663 hypothetical protein LOC205147 [Homo sapiens]
Length = 861
Score = 79.3 bits (194), Expect = 2e-14
Identities = 71/229 (31%), Positives = 90/229 (39%), Gaps = 44/229 (19%)
Query: 315 DVTSLKSFDSLTGCGDIIA-EQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMA 373
DV SL+SFDSLTGCG++ A E + S+ + G + QG E++A
Sbjct: 237 DVASLQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLA 296
Query: 374 LPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGH 433
P + E D W++ R P S G
Sbjct: 297 SP-----------------------AQNEASDFTRFWDSVNRSVRQQQRALLGPWLS-GP 332
Query: 434 HGYMLLDPVRSYPGLAPGELL-----------------TPQSDQQESAPNSDEGYYDSTT 476
G GLA L TP+S+Q ES SDEGYYDS +
Sbjct: 333 QGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFS 392
Query: 477 PGFEDDSGEALGL-VRRDCLPRDSYSGDALYE-FYEPDDSLENSPPGDD 523
PG E+D EA PRDSYSGDALYE F++P + P DD
Sbjct: 393 PGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGPLGPSPDDD 441
>gi|157427661 hypothetical protein LOC205147 [Homo sapiens]
Length = 861
Score = 79.3 bits (194), Expect = 2e-14
Identities = 71/229 (31%), Positives = 90/229 (39%), Gaps = 44/229 (19%)
Query: 315 DVTSLKSFDSLTGCGDIIA-EQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMA 373
DV SL+SFDSLTGCG++ A E + S+ + G + QG E++A
Sbjct: 237 DVASLQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLA 296
Query: 374 LPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGH 433
P + E D W++ R P S G
Sbjct: 297 SP-----------------------AQNEASDFTRFWDSVNRSVRQQQRALLGPWLS-GP 332
Query: 434 HGYMLLDPVRSYPGLAPGELL-----------------TPQSDQQESAPNSDEGYYDSTT 476
G GLA L TP+S+Q ES SDEGYYDS +
Sbjct: 333 QGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFS 392
Query: 477 PGFEDDSGEALGL-VRRDCLPRDSYSGDALYE-FYEPDDSLENSPPGDD 523
PG E+D EA PRDSYSGDALYE F++P + P DD
Sbjct: 393 PGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGPLGPSPDDD 441
>gi|157427667 hypothetical protein LOC205147 [Homo sapiens]
Length = 861
Score = 79.3 bits (194), Expect = 2e-14
Identities = 71/229 (31%), Positives = 90/229 (39%), Gaps = 44/229 (19%)
Query: 315 DVTSLKSFDSLTGCGDIIA-EQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMA 373
DV SL+SFDSLTGCG++ A E + S+ + G + QG E++A
Sbjct: 237 DVASLQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLA 296
Query: 374 LPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGH 433
P + E D W++ R P S G
Sbjct: 297 SP-----------------------AQNEASDFTRFWDSVNRSVRQQQRALLGPWLS-GP 332
Query: 434 HGYMLLDPVRSYPGLAPGELL-----------------TPQSDQQESAPNSDEGYYDSTT 476
G GLA L TP+S+Q ES SDEGYYDS +
Sbjct: 333 QGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFS 392
Query: 477 PGFEDDSGEALGL-VRRDCLPRDSYSGDALYE-FYEPDDSLENSPPGDD 523
PG E+D EA PRDSYSGDALYE F++P + P DD
Sbjct: 393 PGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGPLGPSPDDD 441
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/262 (27%), Positives = 95/262 (36%), Gaps = 63/262 (24%)
Query: 157 EKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQSEP-------------GAKGPERVRAR 203
+ FPS P KG S K +TGA +S P GA+G +
Sbjct: 114 KSFPS--SPSKG-----GSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSE 166
Query: 204 PHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMACKDPEKPME 263
P +S P + K PG P PE PP + D +
Sbjct: 167 PPPATTSPEGQPKVHRARKTMSK--------PGNGQPPVPEKRPPEIQHFRMSDDVHSLG 218
Query: 264 ACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFD 323
S + + L E E G +GEV +L GD SL+ ++
Sbjct: 219 KVTSDLAKRRKLNSGGGLSE----ELGSARRSGEV-----------TLTKGDPGSLEEWE 263
Query: 324 SLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEE 383
++ G D DS S +R + D E AL + EEEE
Sbjct: 264 TVVG-------DDFSLYYDSY-SVDERVDSDSKS------------EVEALTEQLSEEEE 303
Query: 384 EEEEVELEEEEEEVKEEEEDDD 405
EEEE E EEEEEE +EEEE+D+
Sbjct: 304 EEEEEEEEEEEEEEEEEEEEDE 325
Score = 31.6 bits (70), Expect = 4.5
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 896 LDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLS 947
+D+ E+E L + E +E + ++E+ +EE+EEEE+ E S S
Sbjct: 283 VDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRS 334
Score = 30.8 bits (68), Expect = 7.6
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 893 SRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDS 944
S S+D + + L + E +E + ++E+ +EE+EEEEE E +S
Sbjct: 276 SYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEES 327
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/262 (27%), Positives = 95/262 (36%), Gaps = 63/262 (24%)
Query: 157 EKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQSEP-------------GAKGPERVRAR 203
+ FPS P KG S K +TGA +S P GA+G +
Sbjct: 114 KSFPS--SPSKG-----GSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSE 166
Query: 204 PHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMACKDPEKPME 263
P +S P + K PG P PE PP + D +
Sbjct: 167 PPPATTSPEGQPKVHRARKTMSK--------PGNGQPPVPEKRPPEIQHFRMSDDVHSLG 218
Query: 264 ACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFD 323
S + + L E E G +GEV +L GD SL+ ++
Sbjct: 219 KVTSDLAKRRKLNSGGGLSE----ELGSARRSGEV-----------TLTKGDPGSLEEWE 263
Query: 324 SLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEE 383
++ G D DS S +R + D E AL + EEEE
Sbjct: 264 TVVG-------DDFSLYYDSY-SVDERVDSDSKS------------EVEALTEQLSEEEE 303
Query: 384 EEEEVELEEEEEEVKEEEEDDD 405
EEEE E EEEEEE +EEEE+D+
Sbjct: 304 EEEEEEEEEEEEEEEEEEEEDE 325
Score = 31.6 bits (70), Expect = 4.5
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 896 LDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLS 947
+D+ E+E L + E +E + ++E+ +EE+EEEE+ E S S
Sbjct: 283 VDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRS 334
Score = 30.8 bits (68), Expect = 7.6
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 893 SRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDS 944
S S+D + + L + E +E + ++E+ +EE+EEEEE E +S
Sbjct: 276 SYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEES 327
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 53.9 bits (128), Expect = 8e-07
Identities = 74/296 (25%), Positives = 114/296 (38%), Gaps = 31/296 (10%)
Query: 124 PCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKK----GLKGFFSSIRRH 179
P Q S + H + R S A ++A++ F S+P ++ +
Sbjct: 493 PAQMLSVDTGHADRQASGRMDVS-ASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETE 551
Query: 180 RKSKVTGAEQSEPGA--KGPERVRARPHE-----HVSSAPQVPCFEETFQAPRKENANPQ 232
K GAE S G + PE +R P E + + P V + QA +E+ Q
Sbjct: 552 LKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDL--Q 609
Query: 233 DAPGPKVSPTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEK 292
P + P +E P P + H P+P S +P P+
Sbjct: 610 HLPPQPLPPQLSQGDGRSETSQPPTPGSPSHS--PLHSGPRPRRRES---DPTGPQRQVF 664
Query: 293 VVAGEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRAN 352
VA P PLSL + D D+ ++ + + + G
Sbjct: 665 SVAPPFEVNGLPRAVPLSLPYQDFKR-----------DLSDYRERARLLNRVRRVGFSHM 713
Query: 353 RDGTKRSSCL-VTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
T + V Q G+E +++DEEEEEE+E E EEEEEE +EEEE+++ E
Sbjct: 714 LLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Score = 30.4 bits (67), Expect = 10.0
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 917 ESDELQAQQEDSDEEDEEEEEGE 939
E DE + ++E+ +EE+EEEEE E
Sbjct: 746 EEDEEEEEEEEEEEEEEEEEEEE 768
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 52.0 bits (123), Expect = 3e-06
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 45/242 (18%)
Query: 176 IRRHRKSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAP 235
+R R +K E GA RA+P S P E P P
Sbjct: 682 LREVRLAKEKEEESLNQGA------RAQPQAKAESKP--------------EEEEPAKLP 721
Query: 236 GPKVSPTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVA 295
V+P P P +K E EA ++ + P E + E ET EK
Sbjct: 722 AVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEM---PGEEGETAGEG---ETEEKS-G 774
Query: 296 GEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDG 355
GE P G+ + G + + G GD E + + A G+ +G
Sbjct: 775 GETQPE----GEGETETQGKGEECEDENEAEGKGDNEGEDE----GEIHAEDGEMKGNEG 826
Query: 356 TKRSSCLVTYQGG---GEEMALPD-------DDDEEEEEEEEVELEEEEEEVKEEEEDDD 405
S L G +E + D D +EEEEEEEE E EEEEEE +EEEE+++
Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886
Query: 406 LE 407
E
Sbjct: 887 EE 888
Score = 35.0 bits (79), Expect = 0.40
Identities = 15/46 (32%), Positives = 26/46 (56%)
Query: 914 GYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWP 959
G E +E + ++++ +EE+EE+EE E + E P + DWP
Sbjct: 857 GDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWP 902
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 51.2 bits (121), Expect = 5e-06
Identities = 85/347 (24%), Positives = 124/347 (35%), Gaps = 58/347 (16%)
Query: 231 PQDAPGPKVSPT--PEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPE 288
P A P ++PT P SPP K E+P E A+ P P P P P
Sbjct: 803 PSGATPPPIAPTGPPTASPPVPAK------EEPEELPAAPGPLPPPPP-------PPPPV 849
Query: 289 TGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGG 348
G + P G G G +L+ ++ E++ + +
Sbjct: 850 PGPVTLPPPQLVPEGTPGG------GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE 903
Query: 349 QRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEED----- 403
+ D + Y EE +++ EEE EEEE ELEEEEEE EEEE+
Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEE---EEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960
Query: 404 DDLEY---LWETAQMYPRPNMNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQ 460
+DLE+ E + P P PT P L P S P + P P
Sbjct: 961 EDLEFGTAGGEVEEGAPPP-------PTLPPA------LPPPESPPKVQPEPEPEPGLLL 1007
Query: 461 QESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPP 520
+ P ++E T P ++ + G V R+ G++ P + +E P
Sbjct: 1008 EVEEPGTEEERGADTAPTLAPEALPSQGEVERE--------GESPAAGPPPQELVEEEPS 1059
Query: 521 GDDCLYDLHGRSSEMFDPFLNFEPFLSSRPPGAMETEEERLVTIQKQ 567
L + E D +P + METE E +K+
Sbjct: 1060 APPTLLE-----EETEDGSDKVQPPPETPAEEEMETETEAEALQEKE 1101
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 51.2 bits (121), Expect = 5e-06
Identities = 54/236 (22%), Positives = 87/236 (36%), Gaps = 24/236 (10%)
Query: 191 EPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKE-NANPQDAPGPKVSPTPEPSPPA 249
EP +GP+R+R+ P + Q P + P+ + P P++ P EP PP
Sbjct: 124 EPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPLEPIPPP 183
Query: 250 TEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPV-GDP 308
+ DP A P A +S +E+ E V+ P GP G P
Sbjct: 184 PSRPLPADPRVAKGLAPRAEASPSSAAVSSLIEKFER----EPVIVASDRPVPGPSPGPP 239
Query: 309 LSLLFGDVTSLKSFDSL-----TGCGDIIAEQDMDS-MTDSMASGGQRANRDGTKRSSCL 362
++ TS L + C ++A D + SG + +C
Sbjct: 240 EPVMLPQPTSQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCF 299
Query: 363 VTYQGGGEEMALPD------------DDDEEEEEEEEVELEEEEEEVKEEEEDDDL 406
V+ G P D +E + +LEEE++E +EEE+D ++
Sbjct: 300 VSDDGPPSHSLCPGPPALASVPVALADPHRPGSQEVDSDLEEEDDEEEEEEKDREI 355
Score = 35.8 bits (81), Expect = 0.24
Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 10/138 (7%)
Query: 975 ISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQLARPSHLHLPM--GP 1032
+ P Q P + P R + PP P RAPG +PS+L +P P
Sbjct: 117 LDPGQSLEPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPP 176
Query: 1033 CYNLQPQASQSMRARPRDV--LLPVDEPSCSSSSGGFSPSPLPQAKPVGITHGIPQLPRV 1090
+ P S+ + A PR L P E S SS++ S + +PV + P +P
Sbjct: 177 LEPIPPPPSRPLPADPRVAKGLAPRAEASPSSAAVS-SLIEKFEREPVIVASDRP-VPGP 234
Query: 1091 RPEHPQ----PQPTHYGP 1104
P P+ PQPT P
Sbjct: 235 SPGPPEPVMLPQPTSQPP 252
Score = 31.2 bits (69), Expect = 5.8
Identities = 38/146 (26%), Positives = 54/146 (36%), Gaps = 16/146 (10%)
Query: 943 DSPLSLYTEPPGAYDWPAWAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMS 1002
+ P L ++P + P+ P PL PGP P +PS Y Q PP+
Sbjct: 128 EGPQRLRSDPGPPTETPSQRPSPLKRAPGP---KPQVPPKPS----YLQMPRMPPPLE-- 178
Query: 1003 ISLSVPESRAPGESGPQLARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSS 1062
+ P SR P + P++A+ P + P V++ D P
Sbjct: 179 -PIPPPPSR-PLPADPRVAKGLAPRAEASPSSAAVSSLIEKFEREP--VIVASDRPVPGP 234
Query: 1063 SSGGFSPSPLPQAKPVGITHGIPQLP 1088
S G P LPQ +PQLP
Sbjct: 235 SPGPPEPVMLPQPTS---QPPVPQLP 257
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 49.7 bits (117), Expect = 2e-05
Identities = 78/308 (25%), Positives = 117/308 (37%), Gaps = 33/308 (10%)
Query: 3 TQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAM--KLF 60
+QKD + GAA+S S+ + EKG++ KA + + R K A K
Sbjct: 747 SQKDR--RRSGAASSSSS---SREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKES 801
Query: 61 GGKKGICTLPSFFGG-GRSKGSGKGSSKKGLSKSKT----HDGLSEAAHGPEDVVSEGTG 115
G P G G S S SS+K +SK +G+S +D S G G
Sbjct: 802 APSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPA-KDAASAGLG 860
Query: 116 FSLPLPELPCQFPSSQSAHGA-LETGSRCKTSVA----GATE-KAVAEKFPSMPKPKKGL 169
+ +F + + L+ R T +A G+T+ K K + K KG
Sbjct: 861 ------SIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGT 914
Query: 170 KGFFSSIRRHRKSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENA 229
KG + +K + G G ++ +A + S A EET + + A
Sbjct: 915 KGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKA---DSCSQAAGTKGAEETSWSGEERAA 971
Query: 230 NPQDAPGPKVSPTPEPSPPATEKM--ACKDPE---KPMEACASAHVQPKPAPEASSLEEP 284
P PK +P P P ++ + +CK PE P EA A V+ E EE
Sbjct: 972 KVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEE 1031
Query: 285 HSPETGEK 292
E E+
Sbjct: 1032 EEEEEEEE 1039
Score = 41.6 bits (96), Expect = 0.004
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 41/217 (18%)
Query: 917 ESDELQAQQEDSDEEDEEEEEGEWSRDSPLS-----LYTEPPGAYDWP---AWAPCPLPV 968
E +E + ++E+ +EEDEEEEEG S +S +Y + + D+P + P P
Sbjct: 268 EEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPT 327
Query: 969 GPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSI---SLSVPESRAPGES-GPQLARPS 1024
P PA +P Q+D + R+ + + +SV A G + P L P
Sbjct: 328 QPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPG 387
Query: 1025 HLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSS---SGGFSPSPLPQAKPVGIT 1081
+ G +++ P +EP + S GG + P P A
Sbjct: 388 DSEIEEG------------------EIVQPEEEPRLALSLFRPGGRAARPTPAASATPTA 429
Query: 1082 HGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGA 1118
+PQ P P P+ G L L E +GA
Sbjct: 430 QPLPQPP--APRAPE------GDDFLSLHAESDGEGA 458
Score = 36.2 bits (82), Expect = 0.18
Identities = 15/22 (68%), Positives = 20/22 (90%)
Query: 375 PDDDDEEEEEEEEVELEEEEEE 396
P++++EEEEEEEE E +EEEEE
Sbjct: 267 PEEEEEEEEEEEEEEEDEEEEE 288
Score = 36.2 bits (82), Expect = 0.18
Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 380 EEEEEEEEVELEEEEEEVKEEEEDDDLEYLWET-AQMYPRPNMNLGYHPTTSP 431
EEEEEEEE E EEEE+E +EE + + ET A +Y +++ + SP
Sbjct: 268 EEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESP 320
Score = 33.9 bits (76), Expect = 0.90
Identities = 17/27 (62%), Positives = 19/27 (70%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEE 396
EE + +EEEEEEEE E EEEEEE
Sbjct: 1013 EEAGVRGGAEEEEEEEEEEEEEEEEEE 1039
Score = 32.3 bits (72), Expect = 2.6
Identities = 68/326 (20%), Positives = 107/326 (32%), Gaps = 55/326 (16%)
Query: 75 GGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPLPELPCQFPSSQSAH 134
G R K G + + + D S+ A P++ S + P P + SS S+
Sbjct: 767 GSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKE--SAPSSGPPPKPPVSSGSGSSSSSS 824
Query: 135 GALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQSEPGA 194
+ ++ VA + V+ P+ GL R R+S+ P
Sbjct: 825 SCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESR-------SPFL 877
Query: 195 KGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMA 254
K ER P E +AP P+K + A K T + P+ +
Sbjct: 878 KPDERA---PTEMAKAAPGST-------KPKKTKVKAK-AGAKKTKGTKGKTKPSKTRKK 926
Query: 255 CKDPEKPMEACASAHVQPKPAPEASSLEEPHSPE----TGEKVVAGEVNPPNGPVGDPLS 310
+ + ++ A S E +GE+ A + P P
Sbjct: 927 VRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPP 986
Query: 311 LLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGE 370
L D ++ D T ++ + A + R GG E
Sbjct: 987 ALTPDSQTV----------------DSSCKTPEVSFLPEEATEEAGVR--------GGAE 1022
Query: 371 EMALPDDDDEEEEEEEEVELEEEEEE 396
E +EEEEEEEE E EEEE++
Sbjct: 1023 E-------EEEEEEEEEEEEEEEEQQ 1041
Score = 32.3 bits (72), Expect = 2.6
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 374 LPDDDDEEE-----EEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYP 417
LP++ EE EEEE E EEEEEE +EEE+ TA P
Sbjct: 1007 LPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAP 1055
Score = 31.6 bits (70), Expect = 4.5
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 7/66 (10%)
Query: 212 PQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMACKDPEKPMEACASAHVQ 271
P P + +P +++P P P P P P P + DP P + S
Sbjct: 187 PPAPSSASSSPSPSPSSSSPSPPPPP---PPPAPPAPPAPRFDIYDPFHPTDEAYS---- 239
Query: 272 PKPAPE 277
P PAPE
Sbjct: 240 PPPAPE 245
Score = 31.2 bits (69), Expect = 5.8
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 880 PRPPPAAMALNRRSRSLDTA-ETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEG 938
P+ P AL S+++D++ +T E+ S L + E ++ E+ +EE+EEEEE
Sbjct: 979 PKAAPPPPALTPDSQTVDSSCKTPEV----SFLPEEATEEAGVRGGAEEEEEEEEEEEEE 1034
Query: 939 EWSRDSPLSLYTEPPGAYDWPAWAP 963
E + + T A P+ AP
Sbjct: 1035 EEEEEQQPATTTATSTAAAAPSTAP 1059
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/36 (61%), Positives = 28/36 (77%)
Query: 376 DDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWE 411
D+DDEE +EEEE E EEEEEE + EE++DLE + E
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQE 472
Score = 35.8 bits (81), Expect = 0.24
Identities = 18/41 (43%), Positives = 30/41 (73%), Gaps = 3/41 (7%)
Query: 370 EEMALPDDDDEEEEEEEEV---ELEEEEEEVKEEEEDDDLE 407
+E + ++++EEEEEEEE E EE+ E+++E +EDD+ E
Sbjct: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 9/41 (21%)
Query: 376 DDDDEEEEEEEEVE---------LEEEEEEVKEEEEDDDLE 407
D+++EEEEEEEE E LE+ +E +++EE+D+ E
Sbjct: 444 DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEE 484
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 370 EEMALPDDDDEEE----EEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGY 425
EE ++++EEE EEEE++E +E +E EEE++++ + P ++ +
Sbjct: 445 EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
Query: 426 HPTTSPG 432
PG
Sbjct: 505 EKNLEPG 511
Score = 31.2 bits (69), Expect = 5.8
Identities = 18/50 (36%), Positives = 26/50 (52%)
Query: 895 SLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDS 944
SLD+ E S E+D+ ++ D +EE+EEEEE E + DS
Sbjct: 412 SLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS 461
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/36 (61%), Positives = 28/36 (77%)
Query: 376 DDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWE 411
D+DDEE +EEEE E EEEEEE + EE++DLE + E
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQE 472
Score = 35.8 bits (81), Expect = 0.24
Identities = 18/41 (43%), Positives = 30/41 (73%), Gaps = 3/41 (7%)
Query: 370 EEMALPDDDDEEEEEEEEV---ELEEEEEEVKEEEEDDDLE 407
+E + ++++EEEEEEEE E EE+ E+++E +EDD+ E
Sbjct: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 9/41 (21%)
Query: 376 DDDDEEEEEEEEVE---------LEEEEEEVKEEEEDDDLE 407
D+++EEEEEEEE E LE+ +E +++EE+D+ E
Sbjct: 444 DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEE 484
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 370 EEMALPDDDDEEE----EEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGY 425
EE ++++EEE EEEE++E +E +E EEE++++ + P ++ +
Sbjct: 445 EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504
Query: 426 HPTTSPG 432
PG
Sbjct: 505 EKNLEPG 511
Score = 31.2 bits (69), Expect = 5.8
Identities = 18/50 (36%), Positives = 26/50 (52%)
Query: 895 SLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDS 944
SLD+ E S E+D+ ++ D +EE+EEEEE E + DS
Sbjct: 412 SLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS 461
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/36 (61%), Positives = 28/36 (77%)
Query: 376 DDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWE 411
D+DDEE +EEEE E EEEEEE + EE++DLE + E
Sbjct: 449 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQE 484
Score = 35.8 bits (81), Expect = 0.24
Identities = 18/41 (43%), Positives = 30/41 (73%), Gaps = 3/41 (7%)
Query: 370 EEMALPDDDDEEEEEEEEV---ELEEEEEEVKEEEEDDDLE 407
+E + ++++EEEEEEEE E EE+ E+++E +EDD+ E
Sbjct: 452 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 492
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 9/41 (21%)
Query: 376 DDDDEEEEEEEEVE---------LEEEEEEVKEEEEDDDLE 407
D+++EEEEEEEE E LE+ +E +++EE+D+ E
Sbjct: 456 DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEE 496
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 370 EEMALPDDDDEEE----EEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGY 425
EE ++++EEE EEEE++E +E +E EEE++++ + P ++ +
Sbjct: 457 EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 516
Query: 426 HPTTSPG 432
PG
Sbjct: 517 EKNLEPG 523
Score = 31.2 bits (69), Expect = 5.8
Identities = 18/50 (36%), Positives = 26/50 (52%)
Query: 895 SLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDS 944
SLD+ E S E+D+ ++ D +EE+EEEEE E + DS
Sbjct: 424 SLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDS 473
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
Query: 330 DIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVE 389
++ E+ D S+ A+ + +K+ L + EE ++++E+EEEEEE E
Sbjct: 226 EVTTERSQDLCPQSLEDA---ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEE 282
Query: 390 LEEEEEEVKEEEEDDDLE 407
EEEEEE +EEEE+++ E
Sbjct: 283 EEEEEEEEEEEEEEEEEE 300
Score = 48.1 bits (113), Expect = 5e-05
Identities = 25/44 (56%), Positives = 32/44 (72%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETA 413
EE +++DEEEEEEEE E EEEEEE +EEEE+++ E E A
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 43.9 bits (102), Expect = 9e-04
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTT 429
EE ++++EEEEEEEE E EEEEEE +EEE D+ + +T+ + L +
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESP 334
Query: 430 SPGHHGYMLLDPVRS 444
SP Y ++ VRS
Sbjct: 335 SPKPE-YSVIVEVRS 348
Score = 32.7 bits (73), Expect = 2.0
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 905 ELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGE 939
E S + + E DE + ++E+ +EEDEEEEE E
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEE 281
Score = 31.6 bits (70), Expect = 4.5
Identities = 14/31 (45%), Positives = 21/31 (67%)
Query: 909 SHLVQGYLESDELQAQQEDSDEEDEEEEEGE 939
SH + E +E + ++ED +EE+EEEEE E
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE 286
Score = 31.2 bits (69), Expect = 5.8
Identities = 13/35 (37%), Positives = 23/35 (65%)
Query: 917 ESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTE 951
E +E + ++E+ +EE+EEEEE E +P ++ E
Sbjct: 281 EEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315
Score = 30.4 bits (67), Expect = 10.0
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 917 ESDELQAQQEDSDEEDEEEEEGE 939
E DE + ++E+ +EE+EEEEE E
Sbjct: 272 EEDEEEEEEEEEEEEEEEEEEEE 294
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/51 (47%), Positives = 35/51 (68%)
Query: 357 KRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
+R L + EE +D++EEEEEEEE E EEEEEE +EEEE+++++
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
Score = 44.7 bits (104), Expect = 5e-04
Identities = 22/41 (53%), Positives = 30/41 (73%)
Query: 377 DDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYP 417
+++EEEE+EEE E EEEEEE +EEEE+++ E E Q P
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110
Score = 43.9 bits (102), Expect = 9e-04
Identities = 19/44 (43%), Positives = 32/44 (72%)
Query: 376 DDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRP 419
+++++EEEEEEE E EE+EEE +EEEE+++ E + + +P
Sbjct: 1073 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
Score = 41.6 bits (96), Expect = 0.004
Identities = 40/130 (30%), Positives = 56/130 (43%), Gaps = 27/130 (20%)
Query: 375 PDDD----DEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTS 430
P+DD +EEEEEEEE E EEEEEE +EEE ++E + A+ + P S
Sbjct: 1343 PEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKE------EPEIS 1396
Query: 431 PGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLV 490
LD + + +E + N D D EDDS V
Sbjct: 1397 TEKEDSARLDDHEE-----------EEEEDEEPSHNEDHDADD------EDDSHMESAEV 1439
Query: 491 RRDCLPRDSY 500
++ LPR+S+
Sbjct: 1440 EKEELPRESF 1449
Score = 41.2 bits (95), Expect = 0.006
Identities = 22/39 (56%), Positives = 26/39 (66%)
Query: 369 GEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
GE L + E EEEEE E EEEEEE +EEEED++ E
Sbjct: 1056 GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094
Score = 38.5 bits (88), Expect = 0.037
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 904 MELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPP 953
+ELS + E DE + ++E+ +EEDEEEEE E + ++ + PP
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111
Score = 33.1 bits (74), Expect = 1.5
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 4/44 (9%)
Query: 366 QGGGEEMALPDDDDEEEEEEEEVELEEEE----EEVKEEEEDDD 405
+GGG PD +E+EE E+ E+E+ ++ +EEEE+D+
Sbjct: 1373 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDE 1416
Score = 32.7 bits (73), Expect = 2.0
Identities = 16/48 (33%), Positives = 29/48 (60%)
Query: 892 RSRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGE 939
+++ L + E+ + L++ ES E + ++ED +EE+EEEEE E
Sbjct: 1042 KNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE 1089
Score = 32.7 bits (73), Expect = 2.0
Identities = 14/33 (42%), Positives = 24/33 (72%)
Query: 375 PDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
P+ E+ E++ ++ EEEEEE +EEEE+++ E
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1367
Score = 32.3 bits (72), Expect = 2.6
Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 15/103 (14%)
Query: 378 DDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPR-------PNMNLGYHPTTS 430
DD EEEEEE+ E E+ ++E+D +E + PR N
Sbjct: 1406 DDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQ 1465
Query: 431 PGH-HGYMLLD---PVRSYPGLAPGELLTPQSDQQESAPNSDE 469
PGH + +L+D + + P EL + E+ P SDE
Sbjct: 1466 PGHSNPEVLMDCGVDLTASCNSEPKEL----AGDPEAVPESDE 1504
Score = 30.8 bits (68), Expect = 7.6
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 9/90 (10%)
Query: 863 PWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAETLEMELSNSHLVQGYLESDELQ 922
P V S +YL P P L S + E E E E +E +
Sbjct: 1036 PAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE---------EEEEEE 1086
Query: 923 AQQEDSDEEDEEEEEGEWSRDSPLSLYTEP 952
++++ +EE+EEEEE E + S T+P
Sbjct: 1087 EEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
Score = 30.8 bits (68), Expect = 7.6
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 886 AMALNRRSRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSP 945
A+ +R +T + S + L E + ++E+ +EE+EEEEEGE +
Sbjct: 1317 ALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE-EEEGG 1375
Query: 946 LSLYTEPPGA 955
++ +P GA
Sbjct: 1376 GNVEKDPDGA 1385
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 48.5 bits (114), Expect = 4e-05
Identities = 25/56 (44%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Query: 352 NRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
NR R++ LV + ++ LP +++E EEEEEEVE EE+EEE +E+EE+++ E
Sbjct: 95 NRLSVARTAALVAEECSAQQ-GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKE 149
Score = 39.3 bits (90), Expect = 0.021
Identities = 17/38 (44%), Positives = 30/38 (78%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
EE +++++EEE+EE+ E EE+EEE +E+EE+++ E
Sbjct: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
Score = 37.0 bits (84), Expect = 0.11
Identities = 16/32 (50%), Positives = 25/32 (78%)
Query: 376 DDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
+++ EE+EEEEE E E+EE+E +EE+E +E
Sbjct: 136 EEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
Score = 36.6 bits (83), Expect = 0.14
Identities = 17/34 (50%), Positives = 26/34 (76%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEED 403
EE D+++EE+EEE+E + EEEE+E K+ EE+
Sbjct: 136 EEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
Score = 35.8 bits (81), Expect = 0.24
Identities = 17/36 (47%), Positives = 26/36 (72%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDD 405
EE ++DEEEEE+EE + E+EEEE KE ++ ++
Sbjct: 133 EEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
Score = 35.4 bits (80), Expect = 0.31
Identities = 16/37 (43%), Positives = 29/37 (78%), Gaps = 5/37 (13%)
Query: 376 DDDDEEEEEEEEVELEEEEEE-----VKEEEEDDDLE 407
++D+EEEE+EEE E +EEEEE ++EE+ +++++
Sbjct: 140 EEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
Score = 34.7 bits (78), Expect = 0.53
Identities = 17/38 (44%), Positives = 26/38 (68%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
EE +++ EE+EEEEE E ++ EEE EEE D +++
Sbjct: 143 EEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
Score = 32.0 bits (71), Expect = 3.4
Identities = 16/40 (40%), Positives = 25/40 (62%)
Query: 370 EEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYL 409
EE ++DEEEEE+E ++EEE+ E + + E +YL
Sbjct: 146 EEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQYL 185
Score = 30.4 bits (67), Expect = 10.0
Identities = 13/23 (56%), Positives = 17/23 (73%)
Query: 917 ESDELQAQQEDSDEEDEEEEEGE 939
E DE + ++E+ EEDEEEEE E
Sbjct: 140 EEDEEEEEKEEEKEEDEEEEEKE 162
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 48.1 bits (113), Expect = 5e-05
Identities = 22/28 (78%), Positives = 25/28 (89%)
Query: 375 PDDDDEEEEEEEEVELEEEEEEVKEEEE 402
PDDD+E+EEEEEE E EEEEEE +EEEE
Sbjct: 41 PDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
Score = 45.4 bits (106), Expect = 3e-04
Identities = 21/27 (77%), Positives = 24/27 (88%)
Query: 377 DDDEEEEEEEEVELEEEEEEVKEEEED 403
DDDEE+EEEEE E EEEEEE +EEEE+
Sbjct: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEE 68
Score = 42.7 bits (99), Expect = 0.002
Identities = 19/27 (70%), Positives = 24/27 (88%)
Query: 378 DDEEEEEEEEVELEEEEEEVKEEEEDD 404
DD+EE+EEEE E EEEEEE +EEEE++
Sbjct: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEE 68
Score = 32.3 bits (72), Expect = 2.6
Identities = 17/49 (34%), Positives = 27/49 (55%)
Query: 897 DTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSP 945
+ A T S+S V G + +E + ++E+ +EE+EEEEE E P
Sbjct: 23 EEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
Score = 32.3 bits (72), Expect = 2.6
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 349 QRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEE 396
+ A + SS V+ EE ++++EEEEEEEE EEEEEE
Sbjct: 24 EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE---EEEEEE 68
Score = 30.8 bits (68), Expect = 7.6
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 917 ESDELQAQQEDSDEEDEEEEEGEWSRDSP 945
E DE + ++E+ +EE+EEEEE E + P
Sbjct: 45 EEDEEEEEEEEEEEEEEEEEEEEEAPPPP 73
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 47.8 bits (112), Expect = 6e-05
Identities = 35/97 (36%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 581 QEARAREAHAREAHAREAYTREAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQV 640
++ R +A EA A EA +A G EA A EA EA EAR EA+A EVR E +
Sbjct: 405 RDPRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARG 464
Query: 641 RETQARQEKPVLEYQMRPLGPSVMGLAAGV-SGTSQI 676
+T+ P GPS + + A V G+ Q+
Sbjct: 465 MDTRGPVPGPRGPIPSGMQGPSPINMGAVVPQGSRQV 501
>gi|38372931 brevican isoform 2 [Homo sapiens]
Length = 671
Score = 47.8 bits (112), Expect = 6e-05
Identities = 58/221 (26%), Positives = 79/221 (35%), Gaps = 36/221 (16%)
Query: 265 CASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFD- 323
C QP PEAS NP + P D L + +L+
Sbjct: 352 CFRDSAQPSAIPEAS-------------------NPASNPASDGLEAIVTVTETLEELQL 392
Query: 324 --SLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEE 381
T A + M D GG D + L+ ++ + M P EE
Sbjct: 393 PQEATESESRGAIYSIPIMEDG--GGGSSTPEDPAEAPRTLLEFET--QSMVPPTGFSEE 448
Query: 382 E----EEEEEVELEEE-EEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGHHGY 436
E EEEE+ E EEE EEE +EEE +D+ + W + P P +L PT
Sbjct: 449 EGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASL---PTEPAAQEES 505
Query: 437 MLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTP 477
+ P R+ L PG P + + S P G T P
Sbjct: 506 LSQAPARAV--LQPGASPLPDGESEASRPPRVHGPPTETLP 544
Score = 37.4 bits (85), Expect = 0.081
Identities = 55/217 (25%), Positives = 79/217 (36%), Gaps = 46/217 (21%)
Query: 902 LEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPAW 961
LE E + G+ E + ++E+ E++EE+EE E + E + WP+
Sbjct: 432 LEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEE------VEDEALWAWPSE 485
Query: 962 APCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAP-GESGPQL 1020
P P P P + SQ+P R L S P GES +
Sbjct: 486 LSSPGPEASLPT--EPAAQEESLSQAPARAV------------LQPGASPLPDGES--EA 529
Query: 1021 ARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGI 1080
+RP +H GP P + A P SPS L +A+ VG
Sbjct: 530 SRPPRVH---GPPTETLPTPRERNLASP-------------------SPSTLVEAREVGE 567
Query: 1081 THGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQG 1117
G P+L V + + G SL L RA +G
Sbjct: 568 ATGGPELSGVPRGESEETGSSEGAPSL-LPATRAPEG 603
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 47.8 bits (112), Expect = 6e-05
Identities = 58/221 (26%), Positives = 79/221 (35%), Gaps = 36/221 (16%)
Query: 265 CASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFD- 323
C QP PEAS NP + P D L + +L+
Sbjct: 352 CFRDSAQPSAIPEAS-------------------NPASNPASDGLEAIVTVTETLEELQL 392
Query: 324 --SLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEE 381
T A + M D GG D + L+ ++ + M P EE
Sbjct: 393 PQEATESESRGAIYSIPIMEDG--GGGSSTPEDPAEAPRTLLEFET--QSMVPPTGFSEE 448
Query: 382 E----EEEEEVELEEE-EEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGHHGY 436
E EEEE+ E EEE EEE +EEE +D+ + W + P P +L PT
Sbjct: 449 EGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASL---PTEPAAQEES 505
Query: 437 MLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTP 477
+ P R+ L PG P + + S P G T P
Sbjct: 506 LSQAPARAV--LQPGASPLPDGESEASRPPRVHGPPTETLP 544
Score = 37.4 bits (85), Expect = 0.081
Identities = 55/217 (25%), Positives = 79/217 (36%), Gaps = 46/217 (21%)
Query: 902 LEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPAW 961
LE E + G+ E + ++E+ E++EE+EE E + E + WP+
Sbjct: 432 LEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEE------VEDEALWAWPSE 485
Query: 962 APCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAP-GESGPQL 1020
P P P P + SQ+P R L S P GES +
Sbjct: 486 LSSPGPEASLPT--EPAAQEESLSQAPARAV------------LQPGASPLPDGES--EA 529
Query: 1021 ARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGI 1080
+RP +H GP P + A P SPS L +A+ VG
Sbjct: 530 SRPPRVH---GPPTETLPTPRERNLASP-------------------SPSTLVEAREVGE 567
Query: 1081 THGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQG 1117
G P+L V + + G SL L RA +G
Sbjct: 568 ATGGPELSGVPRGESEETGSSEGAPSL-LPATRAPEG 603
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 47.4 bits (111), Expect = 8e-05
Identities = 74/305 (24%), Positives = 99/305 (32%), Gaps = 52/305 (17%)
Query: 18 GSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGR 77
G E+ AE A N A GP P +GP T K G +G+ P G
Sbjct: 780 GGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP-----TGEKGEPGPRGLVGPPGSRGNPG 834
Query: 78 SKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPLPELPCQFPSSQSAHGAL 137
S+G + G + + DG P + +G S P P+ P +G
Sbjct: 835 SRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS-PGPQGLAGSPGPHGPNGVP 893
Query: 138 E-TGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHRKSKVTGA-----EQSE 191
G R GAT GF S R GA E
Sbjct: 894 GLKGGRGTQGPPGAT-------------------GFPGSAGRVGPPGPAGAPGPAGPLGE 934
Query: 192 PGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSP--TPEPSPPA 249
PG +GP +R P H + P A P PG K P +P P
Sbjct: 935 PGKEGPPGLRGDPGSHGRVGDRGP-------------AGPPGGPGDKGDPGEDGQPGPDG 981
Query: 250 TEKMACKDPEKPMEACASAH----VQPKPAPEASSLEEPHSPETGEKVVAGEVNPP--NG 303
A ++ + + P P + + + TG+K G V PP NG
Sbjct: 982 PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041
Query: 304 PVGDP 308
PVG+P
Sbjct: 1042 PVGEP 1046
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 47.4 bits (111), Expect = 8e-05
Identities = 22/40 (55%), Positives = 31/40 (77%), Gaps = 3/40 (7%)
Query: 368 GGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLE 407
GGEE DDDD+E++++EE +EEEEE +EE++DDD E
Sbjct: 133 GGEEDDKEDDDDDEDDDDEE---DEEEEEEEEEDDDDDTE 169
Score = 37.0 bits (84), Expect = 0.11
Identities = 14/31 (45%), Positives = 25/31 (80%)
Query: 376 DDDDEEEEEEEEVELEEEEEEVKEEEEDDDL 406
DDDDEE+EEEEE E E+++++ ++ + ++L
Sbjct: 147 DDDDEEDEEEEEEEEEDDDDDTEDFADQENL 177
>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
sapiens]
Length = 1198
Score = 47.0 bits (110), Expect = 1e-04
Identities = 58/240 (24%), Positives = 89/240 (37%), Gaps = 43/240 (17%)
Query: 181 KSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVS 240
+ K GAE S P + P + + P +E AP +E + +D+ + S
Sbjct: 695 EGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEP--APSQEPLSSKDSATSEGS 752
Query: 241 PTPEPSPPATEKMACKDPE--KPMEACASAHVQPKPAPEASSL---EEPHSPETGEKVVA 295
P +PP+ + C++P + + C +P P L + P E+ + +
Sbjct: 753 PPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLP 812
Query: 296 GEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGD---------IIAEQDMDSMTDSMAS 346
+ P V P L D S S D L GD +I E +DS
Sbjct: 813 PCQDLPPSQVSLPAKALTEDTMS--SGDLLAATGDPPAAPRPAFVIPEVRLDS------- 863
Query: 347 GGQRANRDGTKRSSCLVTY-QGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDD 405
TY Q G E D+++ EE EE E EE EE+ E+ DD+
Sbjct: 864 -----------------TYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDN 906
>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
sapiens]
Length = 519
Score = 47.0 bits (110), Expect = 1e-04
Identities = 58/240 (24%), Positives = 89/240 (37%), Gaps = 43/240 (17%)
Query: 181 KSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVS 240
+ K GAE S P + P + + P +E AP +E + +D+ + S
Sbjct: 16 EGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEP--APSQEPLSSKDSATSEGS 73
Query: 241 PTPEPSPPATEKMACKDPE--KPMEACASAHVQPKPAPEASSL---EEPHSPETGEKVVA 295
P +PP+ + C++P + + C +P P L + P E+ + +
Sbjct: 74 PPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLP 133
Query: 296 GEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGD---------IIAEQDMDSMTDSMAS 346
+ P V P L D S S D L GD +I E +DS
Sbjct: 134 PCQDLPPSQVSLPAKALTEDTMS--SGDLLAATGDPPAAPRPAFVIPEVRLDS------- 184
Query: 347 GGQRANRDGTKRSSCLVTY-QGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDD 405
TY Q G E D+++ EE EE E EE EE+ E+ DD+
Sbjct: 185 -----------------TYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDN 227
>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
sapiens]
Length = 917
Score = 47.0 bits (110), Expect = 1e-04
Identities = 58/240 (24%), Positives = 89/240 (37%), Gaps = 43/240 (17%)
Query: 181 KSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVS 240
+ K GAE S P + P + + P +E AP +E + +D+ + S
Sbjct: 414 EGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEP--APSQEPLSSKDSATSEGS 471
Query: 241 PTPEPSPPATEKMACKDPE--KPMEACASAHVQPKPAPEASSL---EEPHSPETGEKVVA 295
P +PP+ + C++P + + C +P P L + P E+ + +
Sbjct: 472 PPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLP 531
Query: 296 GEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGD---------IIAEQDMDSMTDSMAS 346
+ P V P L D S S D L GD +I E +DS
Sbjct: 532 PCQDLPPSQVSLPAKALTEDTMS--SGDLLAATGDPPAAPRPAFVIPEVRLDS------- 582
Query: 347 GGQRANRDGTKRSSCLVTY-QGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDD 405
TY Q G E D+++ EE EE E EE EE+ E+ DD+
Sbjct: 583 -----------------TYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDN 625
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/278 (25%), Positives = 103/278 (37%), Gaps = 27/278 (9%)
Query: 26 EKGAKNKA---AEATEGPTSEPSSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSG 82
++GA+ K AE +G + P P RL A++ + + L S GG+ K
Sbjct: 243 QRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIR-----RSLEPLLSNSEGGK-KAWA 296
Query: 83 KGSSK--------KGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPLPELPCQ-FPSSQSA 133
K SK + S KT+ H P ++ + FS P P L P+ S
Sbjct: 297 KQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGR--NQSSAFSPPDPALRTHSLPNRPSK 354
Query: 134 HGALETGSRCKT--SVAGATEK-AVAEKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQS 190
C V EK ++ E FP KP K FSS+R KS + ++S
Sbjct: 355 VFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQES 414
Query: 191 EPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPAT 250
K + P V E+ Q P K + Q AP P P P P PP
Sbjct: 415 RQ-RKDIRDLFGSPKRKVLPEDSAQALEKLLQ-PFKSTSLRQAAPPPPPPPPPPPPPPTA 472
Query: 251 EKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPE 288
K+ P+ A + + +SS +E P+
Sbjct: 473 GGADSKN--FPLRAQVTEASSSASSTSSSSADEEFDPQ 508
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,214,221
Number of Sequences: 37866
Number of extensions: 3405866
Number of successful extensions: 52029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 529
Number of HSP's successfully gapped in prelim test: 866
Number of HSP's that attempted gapping in prelim test: 25074
Number of HSP's gapped (non-prelim): 18279
length of query: 1135
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1022
effective length of database: 13,968,660
effective search space: 14275970520
effective search space used: 14275970520
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.