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Search of human proteins with 38176158
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38176158 cyclin K isoform 2 [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38176158 cyclin K isoform 2 [Homo sapiens] 749 0.0
gi|150417989 cyclin K isoform 1 [Homo sapiens] 644 0.0
gi|17978466 cyclin T1 [Homo sapiens] 147 1e-35
gi|17978469 cyclin T2 isoform b [Homo sapiens] 135 7e-32
gi|4502629 cyclin T2 isoform a [Homo sapiens] 135 7e-32
gi|9945320 cyclin L1 [Homo sapiens] 117 2e-26
gi|88758580 cyclin L2 isoform A [Homo sapiens] 115 6e-26
gi|196049382 family with sequence similarity 58, member A isofor... 103 2e-22
gi|196049384 family with sequence similarity 58, member A isofor... 96 4e-20
gi|157502165 family with sequence similarity 58 member B [Homo s... 92 9e-19
gi|61676091 cyclin C isoform a [Homo sapiens] 82 6e-16
gi|221554516 cyclin L2 isoform C [Homo sapiens] 80 2e-15
gi|221554518 cyclin L2 isoform D [Homo sapiens] 78 1e-14
gi|88758578 cyclin L2 isoform B [Homo sapiens] 78 1e-14
gi|61676093 cyclin C isoform b [Homo sapiens] 59 5e-09
gi|4502623 cyclin H [Homo sapiens] 44 2e-04
gi|114431236 zinc finger protein 462 [Homo sapiens] 44 2e-04
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 42 0.001
gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 41 0.002
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 41 0.002
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 41 0.002
gi|16950655 cyclin D1 [Homo sapiens] 40 0.002
gi|161377472 cyclin A1 isoform c [Homo sapiens] 40 0.002
gi|161377470 cyclin A1 isoform c [Homo sapiens] 40 0.002
gi|161377468 cyclin A1 isoform b [Homo sapiens] 40 0.002
gi|4502611 cyclin A1 isoform a [Homo sapiens] 40 0.002
gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 40 0.003
gi|4502613 cyclin A [Homo sapiens] 40 0.003
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 40 0.004
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 40 0.004
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 749 bits (1934), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
Sbjct: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
Query: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
Sbjct: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
Query: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
Sbjct: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
Query: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
Sbjct: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
Query: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
Sbjct: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
Query: 301 QPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG 354
QPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
Sbjct: 301 QPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG 354
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 644 bits (1662), Expect = 0.0
Identities = 314/342 (91%), Positives = 318/342 (92%), Gaps = 14/342 (4%)
Query: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
Sbjct: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
Query: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
Sbjct: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
Query: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
Sbjct: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
Query: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
Sbjct: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
Query: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
Sbjct: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
Query: 301 QPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPA 342
QPQQKDP +QPA P+ +P P P+
Sbjct: 301 QPQQKDP---------QQPAQQQQPAQQP-----KKPSPQPS 328
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 147 bits (371), Expect = 1e-35
Identities = 86/259 (33%), Positives = 141/259 (54%), Gaps = 23/259 (8%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
WY+ ++ L ++PS+ G+DP E YR++ A + D+G RL + T+ T I+Y HRFYM
Sbjct: 12 WYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYM 71
Query: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKE----- 138
SF QFP LFLA KVEE PKK + +IK A + L+ + D E
Sbjct: 72 IQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQE--SLPDTRSEAYLQQ 129
Query: 139 --EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTT 196
++++LE I+LQT+ F+L ++HP+ ++K + ++ K+ Q MA N TT
Sbjct: 130 VQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMA---TNSLHLTT 186
Query: 197 LSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILD 256
SLQ+ P ++A ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 187 FSLQYTPPVVACVCIHLACKWSNWEIPVSTDG---KHWWEYVDATVTLELLDELTHEFL- 242
Query: 257 LYSQGKQQMPHHTPHQLQQ 275
Q+ TP++L++
Sbjct: 243 -------QILEKTPNRLKR 254
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 135 bits (339), Expect = 7e-32
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
Query: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
Query: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
Query: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
Query: 258 YSQGKQQMPHHTPHQLQQ 275
Q+ TP++L++
Sbjct: 242 ------QILEKTPNRLKK 253
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 135 bits (339), Expect = 7e-32
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
Query: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
Query: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
Query: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
Query: 258 YSQGKQQMPHHTPHQLQQ 275
Q+ TP++L++
Sbjct: 242 ------QILEKTPNRLKK 253
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 117 bits (292), Expect = 2e-26
Identities = 79/260 (30%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 11 SVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDT 70
S S +DH+ ++ L+ TPS +GLD +E R G I G L L
Sbjct: 48 SEVSLTIDHS----LIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVA 103
Query: 71 LATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLL------ 124
+ATG + FHRF+ SF + + C+ LA K+EE P++ +D+I L
Sbjct: 104 MATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKR 163
Query: 125 --NDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLV 182
+ + Q + K +V+ ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LV
Sbjct: 164 TPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QTLV 221
Query: 183 QMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDV 242
Q AW ++NDSL T + ++++PE IA A +YLA R + + P W+ F
Sbjct: 222 QTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPL------PTRPHWFLLF--GT 273
Query: 243 PVDVLEDICHQILDLYSQGK 262
+ +++IC + L LY++ K
Sbjct: 274 TEEEIQEICIETLRLYTRKK 293
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 115 bits (288), Expect = 6e-26
Identities = 77/245 (31%), Positives = 125/245 (51%), Gaps = 18/245 (7%)
Query: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
Query: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
Query: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWE 202
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W ++NDSL T + ++++
Sbjct: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSWNYMNDSLRTDVFVRFQ 236
Query: 203 PEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK 262
PE IA A +YLA R + + P W+ F + +++IC +IL LY++ K
Sbjct: 237 PESIACACIYLAARTLEIPL------PNRPHWFLLF--GATEEEIQEICLKILQLYARKK 288
Query: 263 QQMPH 267
+ H
Sbjct: 289 VDLTH 293
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 103 bits (258), Expect = 2e-22
Identities = 63/231 (27%), Positives = 117/231 (50%), Gaps = 22/231 (9%)
Query: 43 PATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFL 102
PA EAR ARFI + G +LG+ +AT +H+F+ + + Y+ ++L
Sbjct: 20 PAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYL 79
Query: 103 AGKVEETPKKCKDIIKTARSLLN--------DVQFGQFGDDPKEEVMVLERILLQTIKFD 154
AGKVEE + +DII + N D +F + ++ ++ E ++L+ ++F
Sbjct: 80 AGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWEL----RDSIVQCELLMLRVLRFQ 135
Query: 155 LQVEHPYQFLLKYAKQLKGDKNKIQ----KLVQMAWTFVNDSLCTTLSLQWEPEIIAVAV 210
+ +HP+++LL Y L+ N+ + AW + DS L L+++ + IAVAV
Sbjct: 136 VSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAV 195
Query: 211 MYLAGRLCKFEI--QEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYS 259
+YLA ++ E+ + KP WW+ F D+ ++++I ++ +Y+
Sbjct: 196 LYLALQVYGVEVPAEVEAEKP----WWQVFNDDLTKPIIDNIVSDLIQIYT 242
>gi|196049384 family with sequence similarity 58, member A isoform 2
[Homo sapiens]
Length = 228
Score = 96.3 bits (238), Expect = 4e-20
Identities = 60/216 (27%), Positives = 107/216 (49%), Gaps = 22/216 (10%)
Query: 43 PATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFL 102
PA EAR ARFI + G +LG+ +AT +H+F+ + + Y+ ++L
Sbjct: 20 PAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYL 79
Query: 103 AGKVEETPKKCKDIIKTARSLLN--------DVQFGQFGDDPKEEVMVLERILLQTIKFD 154
AGKVEE + +DII + N D +F + ++ ++ E ++L+ ++F
Sbjct: 80 AGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWEL----RDSIVQCELLMLRVLRFQ 135
Query: 155 LQVEHPYQFLLKYAKQLKGDKNKIQ----KLVQMAWTFVNDSLCTTLSLQWEPEIIAVAV 210
+ +HP+++LL Y L+ N+ + AW + DS L L+++ + IAVAV
Sbjct: 136 VSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAV 195
Query: 211 MYLAGRLCKFEI--QEWTSKPMYRRWWEQFVQDVPV 244
+YLA ++ E+ + KP WW+ + D +
Sbjct: 196 LYLALQVYGVEVPAEVEAEKP----WWQIYTMDTEI 227
>gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
Length = 252
Score = 91.7 bits (226), Expect = 9e-19
Identities = 59/224 (26%), Positives = 106/224 (47%), Gaps = 10/224 (4%)
Query: 44 ATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLA 103
A AR ARFI + G +LG+ +AT + +F+ F Y+ ++LA
Sbjct: 25 APAARVHFRVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLA 84
Query: 104 GKVEETPKKCKDIIKTARSLLNDVQFGQFGD----DPKEEVMVLERILLQTIKFDLQVEH 159
GKVEE P DII + N D + ++ ++ E ++L+ ++F + +H
Sbjct: 85 GKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQH 144
Query: 160 PYQFLLKYAKQLKGDKN----KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAG 215
P+++LL Y LK N + + AW + DS L L+++ + IAV V+YLA
Sbjct: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLAL 204
Query: 216 RLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYS 259
++ E+ + WW+ F D+ +++ I ++ +Y+
Sbjct: 205 QVYGVEVP--AEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIYT 246
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 82.4 bits (202), Expect = 6e-16
Identities = 83/289 (28%), Positives = 127/289 (43%), Gaps = 31/289 (10%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARF---IFDVGTRLGLHYDTLATGIIYFHR 80
W DK+DL + + L +E Y + F I +G L L +AT +YF R
Sbjct: 14 WILDKQDLLK--ERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKR 71
Query: 81 FYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD-IIKTARSLLNDVQFGQFGDDPKE- 138
FY +S K + C+FLA KVEE +I A S+L F PKE
Sbjct: 72 FYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAF---PKEF 128
Query: 139 -----EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSL 193
++ E LL+ + L V HPY+ LL+Y + D + L+ +AW VND+
Sbjct: 129 PYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQ----DMGQEDMLLPLAWRIVNDTY 184
Query: 194 CTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQ 253
T L L + P +IA+A +++A + + + ++W ++ V ++ + +I
Sbjct: 185 RTDLCLLYPPFMIALACLHVACVVQQKDARQWFAE-----------LSVDMEKILEIIRV 233
Query: 254 ILDLYSQGKQ-QMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ 301
IL LY Q K L + P +P P Q SQ+S SQ
Sbjct: 234 ILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQ 282
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 80.5 bits (197), Expect = 2e-15
Identities = 56/180 (31%), Positives = 87/180 (48%), Gaps = 15/180 (8%)
Query: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
Query: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
Query: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWE 202
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W D L L+W+
Sbjct: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSWVASEDPL-----LKWD 231
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 77.8 bits (190), Expect = 1e-14
Identities = 52/164 (31%), Positives = 81/164 (49%), Gaps = 10/164 (6%)
Query: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
Query: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
Query: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAW 186
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W
Sbjct: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSW 220
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 77.8 bits (190), Expect = 1e-14
Identities = 52/164 (31%), Positives = 81/164 (49%), Gaps = 10/164 (6%)
Query: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
Query: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
Query: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAW 186
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W
Sbjct: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSW 220
>gi|61676093 cyclin C isoform b [Homo sapiens]
Length = 198
Score = 59.3 bits (142), Expect = 5e-09
Identities = 61/211 (28%), Positives = 95/211 (45%), Gaps = 26/211 (12%)
Query: 99 CLFLAGKVEETPKKCKD-IIKTARSLLNDVQFGQFGDDPKE------EVMVLERILLQTI 151
C+FLA KVEE +I A S+L F PKE ++ E LL+ +
Sbjct: 5 CVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAF---PKEFPYRMNHILECEFYLLELM 61
Query: 152 KFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVM 211
L V HPY+ LL+Y + D + L+ +AW VND+ T L L + P +IA+A +
Sbjct: 62 DCCLIVYHPYRPLLQYVQ----DMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACL 117
Query: 212 YLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQ-QMPHHTP 270
++A + + + ++W ++ V ++ + +I IL LY Q K
Sbjct: 118 HVACVVQQKDARQWFAE-----------LSVDMEKILEIIRVILKLYEQWKNFDERKEMA 166
Query: 271 HQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ 301
L + P +P P Q SQ+S SQ
Sbjct: 167 TILSKMPKPKPPPNSEGEQGPNGSQNSSYSQ 197
>gi|4502623 cyclin H [Homo sapiens]
Length = 323
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 9/163 (5%)
Query: 71 LATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFG 130
+ T +YF RFY+ +S ++ + C FLA KV+E + L + G
Sbjct: 80 VGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGN----LRESPLG 135
Query: 131 QFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK---LVQMAWT 187
Q + E+++ E +L+Q + F L V +PY+ + LK ++ L + A
Sbjct: 136 Q--EKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADD 193
Query: 188 FVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPM 230
F+N T L + P IA+ + + ++ + S+ +
Sbjct: 194 FLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESL 236
>gi|114431236 zinc finger protein 462 [Homo sapiens]
Length = 2506
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLE 329
P Q QPP LQP QVP Q+QP + +P P Q PL + C T L
Sbjct: 559 PLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPYKCTMCNYSTTTL------ 612
Query: 330 DSLLCPRPFPHPACLQLGGWGGQP 353
L + H C L + GQP
Sbjct: 613 KGLRVHQQHKHSFCDNLPKFEGQP 636
Score = 35.4 bits (80), Expect = 0.078
Identities = 23/62 (37%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ---PQQKDPLILLQGWACRQPATHLLPS 326
P Q QQPP P P P Q QP Q +P Q P Q P Q +QP +
Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAA 595
Query: 327 PL 328
PL
Sbjct: 596 PL 597
Score = 32.3 bits (72), Expect = 0.66
Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTP-QVPQVQQSQPSQSSEPSQPQQKDP 307
+QQ P P PP QP P Q PQ Q QP P QPQ + P
Sbjct: 538 QQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPH-QVPPQPQTQPP 583
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/50 (42%), Positives = 22/50 (44%)
Query: 258 YSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDP 307
+ Q QQ P P Q PP P P PQ QQ P PS PQQ P
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAP 791
Score = 34.3 bits (77), Expect = 0.17
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 2/78 (2%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLE 329
P LQ PP + P PQ P QP QS P P+ +G ++ A P+ ++
Sbjct: 244 PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG--VKRKADTTTPTTID 301
Query: 330 DSLLCPRPFPHPACLQLG 347
P P P +LG
Sbjct: 302 PIHEPPSLPPEPKTTKLG 319
Score = 32.7 bits (73), Expect = 0.51
Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
Query: 270 PHQLQQPPSLQP----TPQVPQVQQSQPSQ----SSEPSQP--QQKDPLILLQGWACRQP 319
P + +PP++ P TP +PQ +QP Q EP P + LQ QP
Sbjct: 881 PPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP 940
Query: 320 ATHLLPSPLEDSLLCP--RPFPHPACLQ 345
T LLPS S P P PHP+ Q
Sbjct: 941 PTPLLPSVKVQSQPPPPLPPPPHPSVQQ 968
Score = 32.7 bits (73), Expect = 0.51
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 7/59 (11%)
Query: 255 LDLYSQGKQQMPHHTPH------QLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDP 307
+ LY Q Q++ TP Q Q PP L P P P VQQ Q P PQ + P
Sbjct: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH-PSVQQQLQQQPPPPPPPQPQPP 985
Score = 32.0 bits (71), Expect = 0.86
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEP 299
+Q P P Q QQPP P P +P QQ+ P+ S P
Sbjct: 762 QQPPPPPPPQQQQQPPPPPPPPSMP--QQAAPAMKSSP 797
Score = 30.0 bits (66), Expect = 3.3
Identities = 22/68 (32%), Positives = 26/68 (38%), Gaps = 14/68 (20%)
Query: 272 QLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLEDS 331
Q Q PP P PQ P QQ QP P +P P+ Q +TH+ P
Sbjct: 971 QQQPPPPPPPQPQPPPQQQHQP-----PPRPVHLQPM---------QFSTHIQQPPPPQG 1016
Query: 332 LLCPRPFP 339
P P P
Sbjct: 1017 QQPPHPPP 1024
Score = 29.3 bits (64), Expect = 5.6
Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
Query: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKD 306
+ +PPSL P P+ ++ Q + +SS P +P +KD
Sbjct: 303 IHEPPSLPPEPKTTKLGQRR--ESSRPVKPPKKD 334
Score = 28.9 bits (63), Expect = 7.3
Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 7/49 (14%)
Query: 266 PHHTPHQLQQPPS----LQPTPQVPQVQQSQPSQSSEPSQP---QQKDP 307
P P Q QPP LQP +QQ P Q +P P QQ P
Sbjct: 982 PQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
>gi|83977459 pleckstrin homology-like domain, family A, member 1
[Homo sapiens]
Length = 401
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 1/81 (1%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS-QPQQKDPLILLQGWACRQPA 320
+QQ P Q Q P QP PQ QSQP +P QPQQ P P
Sbjct: 304 QQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHPH 363
Query: 321 THLLPSPLEDSLLCPRPFPHP 341
+H P P P P P P
Sbjct: 364 SHPHPHPHPHPHQIPHPHPQP 384
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/46 (50%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 263 QQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ-PQQKDP 307
QQ P TPH Q QP Q PQ+Q SQP S +PSQ P Q+ P
Sbjct: 487 QQPPSQTPHA-QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 7/98 (7%)
Query: 258 YSQGKQQMPHH---TPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGW 314
YSQ Q PH P+ QQ + Q P Q Q + QPQQ P L Q
Sbjct: 518 YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
Query: 315 ACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQ 352
A QP + + + + FP P L +G Q
Sbjct: 578 AYPQPQS----QQSQQTAYSQQRFPPPQELSQDSFGSQ 611
Score = 28.5 bits (62), Expect = 9.5
Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQ-----P 319
M P Q PPS+Q +PQV P ++ L G ++ P
Sbjct: 1564 MTRPPPSNYQPPPSMQN--HIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVP 1621
Query: 320 ATHLLPSPLEDSLL 333
A+H+ P+P++ ++
Sbjct: 1622 ASHIAPAPVQPPMI 1635
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/46 (50%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 263 QQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ-PQQKDP 307
QQ P TPH Q QP Q PQ+Q SQP S +PSQ P Q+ P
Sbjct: 487 QQPPSQTPHA-QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 7/98 (7%)
Query: 258 YSQGKQQMPHH---TPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGW 314
YSQ Q PH P+ QQ + Q P Q Q + QPQQ P L Q
Sbjct: 518 YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
Query: 315 ACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQ 352
A QP + + + + FP P L +G Q
Sbjct: 578 AYPQPQS----QQSQQTAYSQQRFPPPQELSQDSFGSQ 611
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 20/124 (16%)
Query: 77 YFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLL----NDVQFGQF 132
Y RF K+ + GA C+F+A K++ET I TA L N ++
Sbjct: 84 YLDRFLSLEPVKKSRLQLLGATCMFVASKMKET------IPLTAEKLCIYTDNSIR---- 133
Query: 133 GDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDS 192
EE++ +E +L+ +K++L P+ F+ + ++ + Q + + A TFV +
Sbjct: 134 ----PEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFV--A 187
Query: 193 LCTT 196
LC T
Sbjct: 188 LCAT 191
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115
++ +VG L +TL + + RF S + + G + LA K EE D
Sbjct: 206 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 265
Query: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170
+F DD K +++ +E +LL+ + FDL V QFLL+Y ++
Sbjct: 266 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 310
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115
++ +VG L +TL + + RF S + + G + LA K EE D
Sbjct: 206 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 265
Query: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170
+F DD K +++ +E +LL+ + FDL V QFLL+Y ++
Sbjct: 266 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 310
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115
++ +VG L +TL + + RF S + + G + LA K EE D
Sbjct: 249 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 308
Query: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170
+F DD K +++ +E +LL+ + FDL V QFLL+Y ++
Sbjct: 309 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 353
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115
++ +VG L +TL + + RF S + + G + LA K EE D
Sbjct: 250 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 309
Query: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170
+F DD K +++ +E +LL+ + FDL V QFLL+Y ++
Sbjct: 310 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 354
>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
Length = 521
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 16/72 (22%)
Query: 270 PHQLQQPPSLQPTPQVP-QVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPL 328
P Q QQP QP Q P Q QQ QP Q +P QP Q+ +HL+P L
Sbjct: 367 PQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQ--------------SHLVPVSL 412
Query: 329 EDSLLCPRPFPH 340
+L+ P PH
Sbjct: 413 -SNLIPGSPLPH 423
Score = 32.0 bits (71), Expect = 0.86
Identities = 17/38 (44%), Positives = 17/38 (44%)
Query: 260 QGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSS 297
Q QQ P Q Q P QP PQ PQ Q P Q S
Sbjct: 368 QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQS 405
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEET-PKKCK 114
++ +VG L +TL + Y RF S + + G + LA K EE P +
Sbjct: 217 WLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVA 276
Query: 115 DIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGD 174
+ + + D + K++V+ +E ++L+ + FDL QFL +Y +
Sbjct: 277 EFV-----YITDDTY------TKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPA 325
Query: 175 KNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLA 214
K++ L + L++ P +IA A +LA
Sbjct: 326 NCKVESLAMFLGEL--SLIDADPYLKYLPSVIAGAAFHLA 363
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 9/56 (16%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTP--------QVPQVQ-QSQPSQSSEPSQPQQKDPL 308
+QQ P P Q QPP QP P Q PQ Q Q QP Q P PQQ+ PL
Sbjct: 1647 QQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
Score = 32.7 bits (73), Expect = 0.51
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 9/53 (16%)
Query: 263 QQMPHHTPHQLQQPPSLQPTPQVPQVQ--------QSQPSQSSEPSQPQQKDP 307
++ P + Q PP QP P PQ Q Q QP Q +P QPQQ P
Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQP-QPQQPPP 1692
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 9/56 (16%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTP--------QVPQVQ-QSQPSQSSEPSQPQQKDPL 308
+QQ P P Q QPP QP P Q PQ Q Q QP Q P PQQ+ PL
Sbjct: 1647 QQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
Score = 32.7 bits (73), Expect = 0.51
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 9/53 (16%)
Query: 263 QQMPHHTPHQLQQPPSLQPTPQVPQVQ--------QSQPSQSSEPSQPQQKDP 307
++ P + Q PP QP P PQ Q Q QP Q +P QPQQ P
Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQP-QPQQPPP 1692
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,762,907
Number of Sequences: 37866
Number of extensions: 821964
Number of successful extensions: 6004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 185
Number of HSP's that attempted gapping in prelim test: 4704
Number of HSP's gapped (non-prelim): 1051
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.