Guide to the Human Genome
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Search of human proteins with 38146116

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38146116 hypothetical protein LOC10712 isoform a [Homo
sapiens]
         (668 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]   1368   0.0  
gi|38146118 hypothetical protein LOC10712 isoform b [Homo sapiens]   1030   0.0  
gi|166795252 hypothetical protein LOC23359 [Homo sapiens]             262   7e-70
gi|189027139 chromosome 9 open reading frame 61 [Homo sapiens]        112   1e-24
gi|189027135 chromosome 9 open reading frame 61 [Homo sapiens]        112   1e-24
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   3e-04
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     45   3e-04
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              44   4e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        44   4e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    44   4e-04
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming...    43   8e-04
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    43   0.001
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    43   0.001
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    43   0.001
gi|112789555 ADAM metallopeptidase with thrombospondin type 1 mo...    42   0.002
gi|89040432 PREDICTED: hypothetical protein [Homo sapiens]             41   0.003
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    41   0.003
gi|153792074 proline rich 12 [Homo sapiens]                            41   0.003
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    41   0.004
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    40   0.005
gi|55750053 atrophin-1 [Homo sapiens]                                  40   0.005
gi|55750041 atrophin-1 [Homo sapiens]                                  40   0.005
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       40   0.005
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       40   0.005
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]            40   0.007
gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo ...    40   0.007
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      40   0.007
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    40   0.007
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    40   0.007
gi|77681565 NG5 protein [Homo sapiens]                                 40   0.007

>gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]
          Length = 668

 Score = 1368 bits (3540), Expect = 0.0
 Identities = 668/668 (100%), Positives = 668/668 (100%)

Query: 1   MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTT 60
           MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTT
Sbjct: 1   MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTT 60

Query: 61  TESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNA 120
           TESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNA
Sbjct: 61  TESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNA 120

Query: 121 QLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGL 180
           QLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGL
Sbjct: 121 QLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGL 180

Query: 181 TICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEE 240
           TICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEE
Sbjct: 181 TICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEE 240

Query: 241 FVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQAT 300
           FVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQAT
Sbjct: 241 FVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQAT 300

Query: 301 LFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVD 360
           LFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVD
Sbjct: 301 LFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVD 360

Query: 361 YVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAAR 420
           YVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAAR
Sbjct: 361 YVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAAR 420

Query: 421 SCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP 480
           SCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP
Sbjct: 421 SCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP 480

Query: 481 ASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARC 540
           ASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARC
Sbjct: 481 ASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARC 540

Query: 541 PSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPD 600
           PSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPD
Sbjct: 541 PSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPD 600

Query: 601 PSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLN 660
           PSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLN
Sbjct: 601 PSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLN 660

Query: 661 GGSRETGL 668
           GGSRETGL
Sbjct: 661 GGSRETGL 668


>gi|38146118 hypothetical protein LOC10712 isoform b [Homo sapiens]
          Length = 572

 Score = 1030 bits (2663), Expect = 0.0
 Identities = 497/497 (100%), Positives = 497/497 (100%)

Query: 172 NLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPL 231
           NLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPL
Sbjct: 76  NLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPL 135

Query: 232 LHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVM 291
           LHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVM
Sbjct: 136 LHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVM 195

Query: 292 GLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLE 351
           GLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLE
Sbjct: 196 GLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLE 255

Query: 352 LQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPP 411
           LQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPP
Sbjct: 256 LQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPP 315

Query: 412 PLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLT 471
           PLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLT
Sbjct: 316 PLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLT 375

Query: 472 PPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSE 531
           PPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSE
Sbjct: 376 PPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSE 435

Query: 532 ACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRF 591
           ACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRF
Sbjct: 436 ACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRF 495

Query: 592 LQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERG 651
           LQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERG
Sbjct: 496 LQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERG 555

Query: 652 TRPHSLSLNGGSRETGL 668
           TRPHSLSLNGGSRETGL
Sbjct: 556 TRPHSLSLNGGSRETGL 572



 Score =  151 bits (382), Expect = 2e-36
 Identities = 77/84 (91%), Positives = 78/84 (92%)

Query: 1  MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTT 60
          MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTT
Sbjct: 1  MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTT 60

Query: 61 TESIKRSCPSWAGFSLAFSGVVGI 84
          TESIKRSCPSWAGFS     V G+
Sbjct: 61 TESIKRSCPSWAGFSNLLFSVCGL 84


>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
          Length = 539

 Score =  262 bits (670), Expect = 7e-70
 Identities = 149/361 (41%), Positives = 206/361 (57%), Gaps = 24/361 (6%)

Query: 5   PSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESI 64
           P+   R+       R L+ LR      + +L LG  Q+ LG L+V  S  A ++TT+  +
Sbjct: 3   PAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSARV 62

Query: 65  KRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLAR 124
           + SCP WAGFS+  SG++G+VSWKRP +LVI+FF LLS +CVML++AGS+LSC+NAQL  
Sbjct: 63  RHSCPFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQLVN 122

Query: 125 DFQQCSL----EGKVCVCCPSVPLLRPCPESGQELKVAP-NSTCDEARGALKNLLFSVCG 179
             + C L      +VCVCC        C   G+ LK+ P    C+  R  LK+LLFSVC 
Sbjct: 123 SLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSVCA 182

Query: 180 LTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLE 239
           L + + I+C L+  +CC+Q+ S D++    P+R  S P  P   T  P   +LH  LD +
Sbjct: 183 LNVLSTIVCALATAMCCMQMVSSDVLQMFLPQR--SHPANPTCVT--PHGTVLHQTLDFD 238

Query: 240 EFVPPVPPPPYYPPEYTCSSETDAQ------------SITYNGSMDSPVPLYPTDCPPSY 287
           EF+PP+PPPPYYPPEYTC+  T+AQ               Y+ +++SP  LYP + PP Y
Sbjct: 239 EFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPY 298

Query: 288 EAVMGLRGDSQATLFDPQLHDGSCICERVAS--IVDVSMDSGSLVLSAIGDLPGGSSPSE 345
           EAV+G    SQ T    Q+ + S      ++     V  DS SL++S  G    GSSPS 
Sbjct: 299 EAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSE-GTATPGSSPSP 357

Query: 346 D 346
           D
Sbjct: 358 D 358



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 50/168 (29%), Positives = 70/168 (41%), Gaps = 20/168 (11%)

Query: 443 VPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP------ASPPPLLLPRSHSDPG 496
           V  G   P ++P    P    + S  +L PPGH  P          P P  + RS SDP 
Sbjct: 344 VSEGTATPGSSPSPDGPVGAPAPSEPAL-PPGHVSPEDPGMGSQVQPGPGRVSRSTSDPT 402

Query: 497 ITTSS---DTADFRDLYTKVLE---EEAASVSSADTGLCSEACLFRLARCPSPKLLRARS 550
           + TSS   D +  R   ++ LE    EA   S++ +   + AC  +L+    P   +   
Sbjct: 403 LCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKT-- 460

Query: 551 AEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKA 598
              +RP P  +  P  S   P  SL D K     R LV +FL+ S  A
Sbjct: 461 --DQRPTP--EPFPATSKERP-RSLVDSKAYADARVLVAKFLEHSHCA 503


>gi|189027139 chromosome 9 open reading frame 61 [Homo sapiens]
          Length = 450

 Score =  112 bits (279), Expect = 1e-24
 Identities = 81/293 (27%), Positives = 130/293 (44%), Gaps = 43/293 (14%)

Query: 93  LVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSL----EGKVCVCCPSVPLLRPC 148
           L+++ F LLSV+CV+L++AG +L C+ AQ      +C L    EGK+C CC      + C
Sbjct: 3   LLVNLFVLLSVVCVLLNLAGFILGCQGAQFVSSVPRCDLVDLGEGKICFCCEEFQPAK-C 61

Query: 149 PESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTL 208
            +    LK+ P   C      LK +LF++C L      +C ++A +  +QIF+     + 
Sbjct: 62  TDKENALKLFPVQPCSAVHLLLKKVLFALCALNALTTTVCLVAAALRYLQIFATR--RSC 119

Query: 209 APERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSI-- 266
             E  +S          P P          ++FVPPVPPP Y+   Y+C+   + + +  
Sbjct: 120 IDESQISAEEAEDHGRIPDP----------DDFVPPVPPPSYFATFYSCTPRMNRRMVGP 169

Query: 267 -------TYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASI 319
                   Y   +       P D PP YEAV+      Q + F  Q+ +GS         
Sbjct: 170 DVIPLPHIYGARIKGVEVFCPLDPPPPYEAVVSQMDQEQGSSF--QMSEGS-------EA 220

Query: 320 VDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRA 372
             + +D G   ++  GD+P  + P+E++       S  +    L R I+  RA
Sbjct: 221 AVIPLDLGCTQVTQDGDIP--NIPAEEN------ASTSTPSSTLVRPIRSRRA 265



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 625 LHLRSCGDLSSSSSLRRLLSGRRLER--GTRPHSLSLNGGSRETGL 668
           LHL+SCGDL + +   R  + RR  R    RPHSL   G  RET L
Sbjct: 407 LHLQSCGDLHTFTPAGRPRAERRPRRVEAERPHSLI--GVIRETVL 450


>gi|189027135 chromosome 9 open reading frame 61 [Homo sapiens]
          Length = 450

 Score =  112 bits (279), Expect = 1e-24
 Identities = 81/293 (27%), Positives = 130/293 (44%), Gaps = 43/293 (14%)

Query: 93  LVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSL----EGKVCVCCPSVPLLRPC 148
           L+++ F LLSV+CV+L++AG +L C+ AQ      +C L    EGK+C CC      + C
Sbjct: 3   LLVNLFVLLSVVCVLLNLAGFILGCQGAQFVSSVPRCDLVDLGEGKICFCCEEFQPAK-C 61

Query: 149 PESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTL 208
            +    LK+ P   C      LK +LF++C L      +C ++A +  +QIF+     + 
Sbjct: 62  TDKENALKLFPVQPCSAVHLLLKKVLFALCALNALTTTVCLVAAALRYLQIFATR--RSC 119

Query: 209 APERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSI-- 266
             E  +S          P P          ++FVPPVPPP Y+   Y+C+   + + +  
Sbjct: 120 IDESQISAEEAEDHGRIPDP----------DDFVPPVPPPSYFATFYSCTPRMNRRMVGP 169

Query: 267 -------TYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASI 319
                   Y   +       P D PP YEAV+      Q + F  Q+ +GS         
Sbjct: 170 DVIPLPHIYGARIKGVEVFCPLDPPPPYEAVVSQMDQEQGSSF--QMSEGS-------EA 220

Query: 320 VDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRA 372
             + +D G   ++  GD+P  + P+E++       S  +    L R I+  RA
Sbjct: 221 AVIPLDLGCTQVTQDGDIP--NIPAEEN------ASTSTPSSTLVRPIRSRRA 265



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 625 LHLRSCGDLSSSSSLRRLLSGRRLER--GTRPHSLSLNGGSRETGL 668
           LHL+SCGDL + +   R  + RR  R    RPHSL   G  RET L
Sbjct: 407 LHLQSCGDLHTFTPAGRPRAERRPRRVEAERPHSLI--GVIRETVL 450


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 79/307 (25%), Positives = 98/307 (31%), Gaps = 41/307 (13%)

Query: 207 TLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSI 266
           TL P   ++ PL PL   SP   P L T+       PP  PP   PP  T        S+
Sbjct: 330 TLPPSPPLATPL-PLAPPSPSAPPSLQTLPS-----PPATPPSQAPPSMTTPPMQAPPSL 383

Query: 267 TYNGSMDSPVPLY--PTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSM 324
                +  P  L       PPS  A+  L+  +  +L  P L                S+
Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLALSSLQ--ATTSLGSPTLQATHSFLTMSPRQTQASL 441

Query: 325 DSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQ-------RSRAGYC-- 375
            S S   S   D P   +P        LQ S+      L   +         S A +   
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501

Query: 376 LSLDCGLRGPFEESPLPRRPPRAARSYSCSAPE-------APPPLGAPTAARSCHRLEGW 428
             L   +  P E       P       S + P        APPPL   +A  +   LE  
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE-T 560

Query: 429 PPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLL 488
           PP   PC              P  APP+   T      S   TPP   PP  ASPP   L
Sbjct: 561 PPCPAPC--------------PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606

Query: 489 PRSHSDP 495
           P     P
Sbjct: 607 PSPPLSP 613



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 31/107 (28%)

Query: 380 CGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPEL 439
           C L+ P   SPL   PP    S +   P+APP L +P        L+G P       P L
Sbjct: 567 CPLQAP--PSPLTTPPPETPSSIATPPPQAPPALASPP-------LQGLPS------PPL 611

Query: 440 RRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPL 486
                     P A PP +AP            PP   PP P + PPL
Sbjct: 612 ---------SPLATPPPQAP-------PXLALPPLQAPPSPPASPPL 642



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 44/142 (30%), Positives = 52/142 (36%), Gaps = 32/142 (22%)

Query: 382 LRGPFEESPLPRRPPRAARSYSCSAPEAP---PPLGAPTAARSCHRLEGWPPWVGPCFPE 438
           L+ PF  SP P  P +A  S   S P +P   PP  AP +      L   P  V P  P 
Sbjct: 661 LQAPF--SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS------LAAPPLQVPPSPPA 712

Query: 439 LRRRVPRGGGRPAAAPPTRAPTRRFSDS-------SGSLTPPGHRPPHPASPP------- 484
                P     P A PP  AP  +   S       S S TPP   PP  A+PP       
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772

Query: 485 -------PLLLPRSHSDPGITT 499
                  PL  P   + P + T
Sbjct: 773 PASLPMSPLAKPPPQAPPALAT 794



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 27/140 (19%)

Query: 389 SPLPRRPPRAARSYSCSAPEAPP---------PLGAPTA----ARSCHRLEG------WP 429
           SPL   PP+A    +    +APP         PL  P+     A + H L+        P
Sbjct: 612 SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671

Query: 430 PWVGPCFPELRRRVPRGGGRPAAAPPT-RAPTRRFSDS-------SGSLTPPGHRPPHPA 481
           P   P  P     V      P+ APP+  AP  +   S       S S TPP   PP  A
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731

Query: 482 SPPPLLLPRSHSDPGITTSS 501
           +PP  + P   + P ++ S+
Sbjct: 732 APPLQVPPSPPASPPMSPSA 751



 Score = 33.1 bits (74), Expect = 0.85
 Identities = 33/125 (26%), Positives = 41/125 (32%), Gaps = 32/125 (25%)

Query: 384 GPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRV 443
           GP   SPL    P   +     A   PPP  A T   +   L   PP   P         
Sbjct: 297 GPLSSSPLATPSPSGTK-----ARPVPPPDNAATPLPAT--LPPSPPLATPL-------- 341

Query: 444 PRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASP-----------PPLLLPRSH 492
                 P A P   AP    +  S   TPP   PP   +P           PP+ +P S 
Sbjct: 342 ------PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395

Query: 493 SDPGI 497
           + P +
Sbjct: 396 TSPSL 400



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 34/118 (28%), Positives = 40/118 (33%), Gaps = 12/118 (10%)

Query: 385 PFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVP 444
           P   +P  + PP    S   S    PPP   P  A    +    PP     FP      P
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP---ASFPGQAPFSP 815

Query: 445 RGG--GRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTS 500
                  P A PP +AP    +       P    PP P + P L  PR    PG  TS
Sbjct: 816 SASLPMSPLATPPPQAPPVLAA-------PLLQVPPSPPASPTLQAPRRPPTPGPDTS 866



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 6/82 (7%)

Query: 210 PERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPP---PYYPPEYTCSSETDAQSI 266
           P    S PL PL   SP     L   L    F PP  PP   P+ PP     S +     
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693

Query: 267 TYNGSMDSP---VPLYPTDCPP 285
               S+ +P   VP  P   PP
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPP 715


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 14/106 (13%)

Query: 385 PFEESPLPRRPPRAARSY-SCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRV 443
           P      P  PPRA R   + +A  APPP  AP            PP   P       R 
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAP------------PPPPAPVAAAAPARA 148

Query: 444 PRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLP 489
           PR     A APP+  P +     +    P    PP PA+PP +  P
Sbjct: 149 PRAAAAAATAPPSPGPAQP-GPRAQRAAPLAAPPPAPAAPPAVAPP 193



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 18/113 (15%)

Query: 390 PLPRRPPRAARSYSCSAPE----APPPLGAPTAA-------RSCHRLEGWPPWVGPCFPE 438
           P P R PR A + + +A      APPP  AP AA       R+       PP  GP  P 
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG 168

Query: 439 LR--RRVPRGGGRPA-AAPPTRAPT----RRFSDSSGSLTPPGHRPPHPASPP 484
            R  R  P     PA AAPP  AP     R    +  +  PP   PP P +PP
Sbjct: 169 PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 37/242 (15%)

Query: 338 PGGSSPSEDSCLLELQGSVR-SVDYVLFRSIQRS----RAGYCLSLDCGLRGPFEESPLP 392
           P G S +E S  L ++ S + S   V  R ++R     R  + L    GL  P     LP
Sbjct: 464 PSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLH-QRGLAVPDGPLGLP 522

Query: 393 RRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAA 452
            +P R  +      P      GA  A    +    W P + P           G  RP  
Sbjct: 523 PKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSP----------GGSRRPPR 572

Query: 453 APP-TRAPTRRFSDSSGSLT-PPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLY 510
           +P  T +P+  +S  SG+ T PP      PASP     P+    P   TS          
Sbjct: 573 SPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPK----PERVTS---------- 618

Query: 511 TKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPA 570
              L    ASVSS+ T LCS +     +    P++L       R  +P   KVP P  P 
Sbjct: 619 ---LRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG--DRFVIPPHPKVPAPFSPP 673

Query: 571 PA 572
           P+
Sbjct: 674 PS 675



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 11/92 (11%)

Query: 208 LAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFV--------PPVPPPPYY-PPEYTCS 258
           LA    V GP+     +   P     T+  L+E          PP PPP Y+ PP  T  
Sbjct: 687 LAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKK 746

Query: 259 SETDAQSITYNGSMDSPV--PLYPTDCPPSYE 288
            E   ++ + + + + P+  P +P   PP+ E
Sbjct: 747 PEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 52/184 (28%), Positives = 67/184 (36%), Gaps = 24/184 (13%)

Query: 385  PFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVP 444
            P  ++P PR  PR +RS S S    P P G+ +   S       PP         + R  
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH----PP---------KSRTA 1668

Query: 445  RGGGRPAAAPPTRA---PTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSS 501
            R G R +  P T++   P RR S SS  LT          S       RS + P    S 
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP 1728

Query: 502  DTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPK---LLRARSAEKRRPVP 558
              +               S SS  T   S     R  R PSPK   L R+RS  +R    
Sbjct: 1729 SVSSPEPAEKSRSSRRRRSASSPRTKTTS-----RRGRSPSPKPRGLQRSRSRSRREKTR 1783

Query: 559  TFQK 562
            T ++
Sbjct: 1784 TTRR 1787



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 50/188 (26%), Positives = 65/188 (34%), Gaps = 65/188 (34%)

Query: 366 SIQRSRAGYCLSLDCGLRGPFEESPLPRR----PPRAARSYSC--------------SAP 407
           S  RS+A   LSL   L G    SP P++    PPR +RS S               S+ 
Sbjct: 763 SSPRSKAKSRLSLRRSLSG---SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS 819

Query: 408 EAPPPLGAPTAARSCHRLE--------GWPPWVGP-----------------CF-----P 437
             PP   + T +R  H           G PP  G                  CF     P
Sbjct: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP 879

Query: 438 ELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPP----LLLPRSHS 493
           EL+ R P       ++PP             S TPP   P   +SP P    ++ PR  S
Sbjct: 880 ELKSRTPSRHSCSGSSPPRVK----------SSTPPRQSPSRSSSPQPKVKAIISPRQRS 929

Query: 494 DPGITTSS 501
             G ++ S
Sbjct: 930 HSGSSSPS 937



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 44/175 (25%), Positives = 60/175 (34%), Gaps = 31/175 (17%)

Query: 394  RPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAA 453
            R P A  + S +    PP      ++    +       VGP        V   G R AAA
Sbjct: 2301 RTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA 2360

Query: 454  -PPTRAPTRRFSD--SSGSLTPPG------HRPPHPASPPPLLLPRSHSDPGITTSSDTA 504
              P    + R +   S  +LT P        R     SPP L   RS + P   + S   
Sbjct: 2361 LAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS--- 2417

Query: 505  DFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPT 559
                   ++  E A S SS            R+ + PS  LL     + R PVP+
Sbjct: 2418 -------RMTSERAPSPSS------------RMGQAPSQSLLPPAQDQPRSPVPS 2453


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 101/403 (25%), Positives = 137/403 (33%), Gaps = 52/403 (12%)

Query: 208  LAPERSVSGPLGPLGCTSPPP--APLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQS 265
            L P  S + P+ P    SP    APL   +L  E  +P   P P  PP  T         
Sbjct: 700  LVPTASENCPVAP----SPQNTCAPLATLVLAPE--IPKSVPSPSLPPAGTPPGTKKVDG 753

Query: 266  ITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLF---DPQLHDGSCICERVASIVDV 322
            I++  ++ +PV   P +CP   ++       S+ TL    D     G  +  +       
Sbjct: 754  ISHTSAL-APVASSPKECPTE-DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811

Query: 323  SMDSGSLVLSAIGDLPGGSSPSEDSCL----LELQGSVRSVDYVLFRSIQRSRAGYCLSL 378
               +G    + IG+L    SP E S L    L  QGS  S       +    +     S 
Sbjct: 812  KGSAGPD--TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869

Query: 379  DC-----GLRGPFEESPLPR--RPPRAARSYSCSAPEAPPPLG----APTAARSCHRLEG 427
                   G+  P +E+P P     P      +  AP+  P L     +P  AR+    +G
Sbjct: 870  VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929

Query: 428  WP----PWVGPCFPELRRRVPRGGGR----------PAAAPPTRAPTRRFSDSSGSLTPP 473
             P    P   P  P      P+GG            PAA PP+           G+ TPP
Sbjct: 930  IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989

Query: 474  GHRPPHPASPPPLLLPRSHSDPGITT--SSDTADFRDLYTKVLEEEAASV------SSAD 525
               PP P   P    P+    P   T  S   +     + K      A+       S A 
Sbjct: 990  AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049

Query: 526  TGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSG 568
            T L   A     A  PSPK   A  + K  P P     P P G
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 7/101 (6%)

Query: 396  PRAARSYSCSAPEAPPPLGAPTA-ARSCHRLEGW---PPWVGPCFPEL-RRRVPRGGGRP 450
            P A        P  PPP GAPT  A +   L+G    PP  G   P +     P+GG  P
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG--P 1301

Query: 451  AAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRS 491
            A +PP  APT   +        PG  PP  A  PP + P S
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 51/212 (24%), Positives = 67/212 (31%), Gaps = 28/212 (13%)

Query: 385  PFEESPLPRRPPRAARSYSCSAPEAP-------PPLGAPTAARSCHR-----LEGWPPWV 432
            P  +  L   PP+ A +   + P +P       PP GAPT   +        L    P  
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG 1193

Query: 433  GPCFPELRRRVPRGG----------GRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPH--- 479
             P  P      P+GG            PAA PP+           G+ T P   PP    
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253

Query: 480  -PASPPP--LLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFR 536
             PA+PPP     P + + P +     T   +      +    +      T     A    
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP 1313

Query: 537  LARCPSPKLLRARSAEKRRPVPTFQKVPLPSG 568
             A  PSPK        K  P P     P P G
Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 40/139 (28%), Positives = 49/139 (35%), Gaps = 26/139 (18%)

Query: 395  PPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAP 454
            PP A       +P  PPP GAPT           PP V P  P+    +P      A  P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPT-----------PPAVTPPSPKGTPTLP------ATTP 1354

Query: 455  PTRAPTRRFSDSSGSLTPPGHRPPH---PASPPPL-----LLPRSHSDPGITTSSDTADF 506
             ++      S   G  TPP   P H   PA  PP       +P    DP        +  
Sbjct: 1355 SSKGGPTTPSSKEGP-TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413

Query: 507  RDLYTKVLEEEAASVSSAD 525
            +   T V  E AA+ S  D
Sbjct: 1414 KAPATPVTREGAATPSKGD 1432



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 52/196 (26%), Positives = 62/196 (31%), Gaps = 44/196 (22%)

Query: 385  PFEESPLPRRPPR----AARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELR 440
            P    P P+ PP     A  S    AP  P P+GAPT            P V P  P   
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL-----------PAVIPSSP--- 1513

Query: 441  RRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTS 500
            + VP     P++     APT          TP    P     PP + +P     P I T 
Sbjct: 1514 KEVP---ATPSSRRDPIAPTATLLSKK---TPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567

Query: 501  SDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSA-----EKRR 555
                          +E  A+ SS +               PSPK L    A      K  
Sbjct: 1568 --------------KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613

Query: 556  PVPTFQKVPLP-SGPA 570
            P P     P P  GPA
Sbjct: 1614 PTPPAVTPPSPEKGPA 1629



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 55/199 (27%), Positives = 68/199 (34%), Gaps = 24/199 (12%)

Query: 383  RGPFEESPLPR---RPPRAARSYSCSAPEAPP-PLGAPTAARSCHRLEGWPPWVGPCFPE 438
            +G    +P P+    PP A       +P A P P GAPT   +        P  GP  P 
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP----SPKGGPATPS 1075

Query: 439  LRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP----ASPPPLLLPRSHSD 494
            L+         PAA PP+           G+  PP   PP P    A+PP    P   + 
Sbjct: 1076 LKGAPTP----PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP---TT 1128

Query: 495  PGITTSSDTADFRDLYTK-VLEEEAASVSSADTGLCSE----ACLFRLARCPSPKLLRAR 549
            P  T  S          K      AA+  S   GL +     A     A  PSPK   A 
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 550  SAEKRRPVPTFQKVPLPSG 568
             + K  P       P P G
Sbjct: 1189 PSPKGAPTTPAATPPSPKG 1207



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 41/145 (28%), Positives = 46/145 (31%), Gaps = 40/145 (27%)

Query: 384  GPFEESPLPR-RPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPE---L 439
            GP   SP     PP A        P  P P GAPT           PP V P  P+    
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT-----------PPAVTPPSPKGSPA 1024

Query: 440  RRRVPRGG------------GRPAAAP-PTRAPTRRFS------------DSSGSLTPPG 474
                P+G             G PAA P P  APT   +               G+ TPP 
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084

Query: 475  HRPPHPASPPPLLLPRSHSDPGITT 499
              PP P   P    P+    P   T
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAAT 1109



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 52/217 (23%), Positives = 74/217 (34%), Gaps = 21/217 (9%)

Query: 390  PLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGR 449
            P  + P          APE+ P + APT  R   + +       P  P+   +    G  
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPT--RKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730

Query: 450  PAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDL 509
               AP    P ++ S  +       H P  P +P     P S +   +T ++        
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP-----PESKASTPLTAAA-------- 1777

Query: 510  YTKVL-EEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSG 568
            + KVL + E+ASVS+A     S      LA  P P L   +      P    +    P  
Sbjct: 1778 FEKVLPKPESASVSAAP----SPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833

Query: 569  PAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTG 605
            PA    L  L    P  G V  F  +    P P   G
Sbjct: 1834 PADEDELLPLIPPEPISGGVP-FQSVLVNMPTPKSAG 1869


>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence-like 1 [Homo sapiens]
          Length = 491

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 29/129 (22%)

Query: 390 PLPRRPPRAARS----YSCSAP----EAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRR 441
           P+P  PP+AA +    YS + P     APPP+  P      H +   PP++    P    
Sbjct: 354 PMPH-PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPG----HIIAQMPPYMN--HPPPGP 406

Query: 442 RVPRGGGRPAAAPPTR----APTRRFSDSSGSLTPPGHRP--------PHPASPPPLLLP 489
             P+ GG P  APP          +F++  G+L+PP  +P        P P  PPP   P
Sbjct: 407 PPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPP--PP 464

Query: 490 RSHSDPGIT 498
           R    P  T
Sbjct: 465 RLQGPPSQT 473



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 26/108 (24%), Positives = 34/108 (31%), Gaps = 4/108 (3%)

Query: 395 PPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAP 454
           PP  A ++     +  P +  P       +    PP   P         P+  G P    
Sbjct: 310 PPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVY 369

Query: 455 PTRAPTRRFSDSSGSLTPPGH----RPPHPASPPPLLLPRSHSDPGIT 498
               P    S       PPGH     PP+   PPP   P  H  P +T
Sbjct: 370 SQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVT 417



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 26/99 (26%), Positives = 38/99 (38%), Gaps = 20/99 (20%)

Query: 204 LVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPP-------------- 249
           LV++ AP   ++    P+   +PPP  ++  M       PP PPPP              
Sbjct: 367 LVYSQAPPPPMTSAPPPI---TPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHH 423

Query: 250 YYP---PEYTCSSETDAQSITYNGSMDSPVPLYPTDCPP 285
           Y P   P++T    T +   T  G M   +   P   PP
Sbjct: 424 YNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPP 462


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 84/335 (25%), Positives = 113/335 (33%), Gaps = 81/335 (24%)

Query: 275 PVPLYPTDC----------PPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSM 324
           P PL+PT            PP+Y+ V     D +    +  L         V + V    
Sbjct: 613 PRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTL---------VGAGVPAGP 663

Query: 325 DSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDC--GL 382
             G    + + +      P ED+  L  QG  +        S Q +     L  +C   L
Sbjct: 664 SQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPS-----SAQTAEIFQALQQECMRQL 718

Query: 383 RGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCH-RLEGWPP-------WVGP 434
           + P   SP P   P          P+ PP +  P      H +L   PP       W GP
Sbjct: 719 QAP-AGSPAPSPSPGGD-----DKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGP 772

Query: 435 CFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPP--PLLLPRSH 492
                             A P R P R        L+P G R P P  PP    L PR  
Sbjct: 773 ------------------ASPPRVPPRE------PLSPQGSRTPSPLVPPGSSPLPPRLS 808

Query: 493 SDPG---ITTSSDTADFRDLYTKVLEEEAASVSSA------DTGLCSEACLFRLARCPS- 542
           S PG    TT S  +D +    +V++               D    S    + L   PS 
Sbjct: 809 SSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSY 868

Query: 543 ----PKLLR-ARSAEKRRPVPTFQKVPLPSGPAPA 572
                + LR A+S E+  P+P    +P PS PAPA
Sbjct: 869 LERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPA 903


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
           sapiens]
          Length = 1086

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 84/335 (25%), Positives = 113/335 (33%), Gaps = 81/335 (24%)

Query: 275 PVPLYPTDC----------PPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSM 324
           P PL+PT            PP+Y+ V     D +    +  L         V + V    
Sbjct: 691 PRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTL---------VGAGVPAGP 741

Query: 325 DSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDC--GL 382
             G    + + +      P ED+  L  QG  +        S Q +     L  +C   L
Sbjct: 742 SQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPS-----SAQTAEIFQALQQECMRQL 796

Query: 383 RGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCH-RLEGWPP-------WVGP 434
           + P   SP P   P          P+ PP +  P      H +L   PP       W GP
Sbjct: 797 QAP-AGSPAPSPSPGGD-----DKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGP 850

Query: 435 CFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPP--PLLLPRSH 492
                             A P R P R        L+P G R P P  PP    L PR  
Sbjct: 851 ------------------ASPPRVPPRE------PLSPQGSRTPSPLVPPGSSPLPPRLS 886

Query: 493 SDPG---ITTSSDTADFRDLYTKVLEEEAASVSSA------DTGLCSEACLFRLARCPS- 542
           S PG    TT S  +D +    +V++               D    S    + L   PS 
Sbjct: 887 SSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSY 946

Query: 543 ----PKLLR-ARSAEKRRPVPTFQKVPLPSGPAPA 572
                + LR A+S E+  P+P    +P PS PAPA
Sbjct: 947 LERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPA 981


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/230 (26%), Positives = 83/230 (36%), Gaps = 44/230 (19%)

Query: 389 SPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVG----PCF-PELRRRV 443
           SP+P+  P         AP   PP   P         +  PP VG    P F P L   +
Sbjct: 656 SPIPKPLPVPVPPIPVPAPITVPPPQVPPH-------QPGPPVVGALQPPAFTPPLG--I 706

Query: 444 PRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASP--PPLLLPRSHSDP------ 495
           P  G  P   PP   P       +    PPG  PP P  P  PP+ +P  H+ P      
Sbjct: 707 PPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNL 766

Query: 496 --GITTSSDTADFRDLYTKVLEEEAAS----------VSSADTGLCSEACLFRLARCPSP 543
             G   ++++ D   +Y   +   A +          VS   T   +   +  L + PS 
Sbjct: 767 VSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGL-QAPST 825

Query: 544 KLLRAR------SAEKRRPVPTFQKVPL-PSGPAPAHSLGDLKGSWPGRG 586
            LL AR            P P  Q+ PL P  P P H +   +G  PG G
Sbjct: 826 GLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMH--RGPPPGPG 873



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 11/79 (13%)

Query: 219 GPLGCTSPPPAPLLHTMLDLEE----FVPPVPPPPYYPPEYTCSSETDAQSITY------ 268
           GP     PPP P L    +       F+PP PPPP  PP       T   SI        
Sbjct: 712 GPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGAR 771

Query: 269 -NGSMDSPVPLYPTDCPPS 286
            N      V +Y +  PP+
Sbjct: 772 GNAESGDSVKMYGSAVPPA 790


>gi|112789555 ADAM metallopeptidase with thrombospondin type 1
           motif, 19 preproprotein [Homo sapiens]
          Length = 1207

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 15/88 (17%)

Query: 409 APPPLGAPTAARSCHRLEGWPPWVGPCFPELR-RRVPRGGGRPAAAPPTRAPTRRFSDSS 467
           AP PL  P   RS  RL   PP  G    EL  + +PRG    AA  P            
Sbjct: 87  APVPLEEPVEGRSESRLRPPPPSEGEEDEELESQELPRGSSGAAALSPG----------- 135

Query: 468 GSLTPPGHRPPHPASPPPLLLPRSHSDP 495
               P   +PP P  PPP   P  H++P
Sbjct: 136 ---APASWQPPPPPQPPPSPPPAQHAEP 160


>gi|89040432 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 212

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/128 (32%), Positives = 52/128 (40%), Gaps = 23/128 (17%)

Query: 385 PFEESPLPRRPPRAARSYSCSAPEAPPPLGAP-------TAARSCH---RLEG------W 428
           P  ++P  +RP R  R +S  AP +  P+ AP       + +R CH   +L         
Sbjct: 35  PLPQTPPTKRPERF-RLHSPRAPGSAQPISAPEGRGGAGSRSRYCHGDGKLAAAAAGTVG 93

Query: 429 PPWV--GPCFPELRR-RVPRGGG---RPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPAS 482
           P W+  G C  E  R R P  GG   RP AA P  +   R    S    P    P    S
Sbjct: 94  PRWLPAGQCLSEAERPRRPEPGGARSRPVAASPAASSRARSRPESSPGAPGSSVPALLPS 153

Query: 483 PPPLLLPR 490
            PPL  PR
Sbjct: 154 LPPLAAPR 161


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/124 (32%), Positives = 48/124 (38%), Gaps = 11/124 (8%)

Query: 384 GPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRV 443
           GP    PLP   P  +R  +CS    P   G   A    H   G P    P   +   R 
Sbjct: 689 GPSRRGPLPC--PLCSREGACSC--LPLERGDAVAGWGGHPALGCPH---PPEDDSSLRA 741

Query: 444 PRGG-GRPAAAPPTRAPTRRFSDSSGSLTP--PGHRPPHPASPPPLLLPRSHSDPGITTS 500
            RG       APP  AP        G+  P  PG  PP PA PPP   PR+ +DP  +  
Sbjct: 742 ERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPP-PAPPPPPPPPRAPADPAASPD 800

Query: 501 SDTA 504
             +A
Sbjct: 801 PPSA 804



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 37/127 (29%), Positives = 49/127 (38%), Gaps = 25/127 (19%)

Query: 454 PPTRAPTRRFSDSSGSLT------PPGHRPPHPASPP-----PLLLPRSHSDPGITTSSD 502
           PP + P+   SD    LT      PP  RPP P  PP     P   P +HS P   T S 
Sbjct: 423 PPAQRPSA--SDLQLQLTYLLSERPP--RPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSS 478

Query: 503 TADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQK 562
                D +     ++  +V+ +  GL  E CL+  AR         R A +    P +Q 
Sbjct: 479 PFPLLDGFPGADPDDVLTVTESSRGLNLE-CLWEKAR---------RGAGRGGGAPAWQP 528

Query: 563 VPLPSGP 569
              P  P
Sbjct: 529 ASAPPAP 535



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 17/68 (25%)

Query: 226 PPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPL-----YP 280
           PPPAP            PP PPPP  P +   S +  +   +    + SP P      Y 
Sbjct: 778 PPPAP------------PPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYE 825

Query: 281 TDCPPSYE 288
           T+ P S E
Sbjct: 826 TETPFSPE 833



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 36/126 (28%), Positives = 40/126 (31%), Gaps = 28/126 (22%)

Query: 385  PFEESPLPRRP-PRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRV 443
            P  E+ L R P P A  S       AP PLG               P  G   P   RR 
Sbjct: 1075 PAPETSLERAPAPSAVVSSRNGGETAPGPLGPA-------------PKNGTLEPGTERRA 1121

Query: 444  PRGGGRPAAAPPTRAPTRRFSDSS-GSLTPPGHRP-------------PHPASPPPLLLP 489
            P  GG P A    R        +  G+ T PG  P               P  PPP L P
Sbjct: 1122 PETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPP 1181

Query: 490  RSHSDP 495
               + P
Sbjct: 1182 PPEAQP 1187


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 69/266 (25%), Positives = 90/266 (33%), Gaps = 66/266 (24%)

Query: 233  HTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMG 292
            H  L      PP+ PP   PP           S+   G    P P  P    P      G
Sbjct: 1295 HPPLYQAGLTPPLSPPKSVPP-----------SVPARGLQPQP-PATPAVPHPPPSGAFG 1342

Query: 293  LRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLEL 352
            L G  +A   +         C+R+   +  ++++          LP  SS  EDS     
Sbjct: 1343 LGGALEAAESEGLGLGCPSPCKRLDEELKRNLET----------LPSFSSDEEDSVAKN- 1391

Query: 353  QGSVRSVDYVLFRSIQRSRAGYCLSLDCG-LRGPFEESPLPRRPPRAARSYSCSAPEAPP 411
                        R +Q S +    +LD   L GP +++  P  PP A      +A   PP
Sbjct: 1392 ------------RDLQESISSAISALDDPPLAGP-KDTSTPDGPPLAP----AAAVPGPP 1434

Query: 412  PLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLT 471
            PL    +A S     G P       P L    P     P   PP   P  +         
Sbjct: 1435 PLPGLPSANS----NGTPE------PPLLEEKP-----PPTPPPAPTPQPQ--------P 1471

Query: 472  PPGHRPPHPA--SPPPLLLPRSHSDP 495
            PP   PP PA  SPPPL+ P   S P
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPTPSSPP 1497



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 45/167 (26%), Positives = 57/167 (34%), Gaps = 33/167 (19%)

Query: 139  CPSVPLLRPCPESGQELK----VAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIV 194
            CPS     PC    +ELK      P+ + DE     KN        +I +AI       +
Sbjct: 1359 CPS-----PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQE---SISSAISALDDPPL 1410

Query: 195  CCIQIFSLDLVHTLAPERSVSGP-----LGPLGCTSPPPAPLLHTMLDLEEFVPPVPPP- 248
               +  S      LAP  +V GP     L        P  PLL      EE  PP PPP 
Sbjct: 1411 AGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLL------EEKPPPTPPPA 1464

Query: 249  ---------PYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPS 286
                     P  PP+    S     + T +     P+P  P    PS
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 36/133 (27%), Positives = 44/133 (33%), Gaps = 14/133 (10%)

Query: 385  PFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVP 444
            P  + P P  PP+ A         +PPPL APT +         PP   P  P      P
Sbjct: 1467 PQPQPPPPPPPPQPALP-------SPPPLVAPTPSSP-------PPPPLPPPPPPAMPSP 1512

Query: 445  RGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTA 504
                 PAAAP    P    + S      P  RP H A           +D     S    
Sbjct: 1513 PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572

Query: 505  DFRDLYTKVLEEE 517
             FR+    V+  E
Sbjct: 1573 IFRERDEFVIRAE 1585


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
          Length = 1258

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 63/237 (26%), Positives = 86/237 (36%), Gaps = 37/237 (15%)

Query: 366  SIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSA----PEAPPPLGAPTAARS 421
            SI +  AG         RG  E     R+P     S   S     PE PPP G P A   
Sbjct: 890  SIDKDEAGAKSKAPSVSRGSQEPRSGSRKPAFTEASCPLSRLFEEPEKPPPTGRPPA--- 946

Query: 422  CHRLEGWPPWVGPCFPELRRRV-PRGGGRP--AAAPPTRAPTRRFSDSSGSL---TPPGH 475
                   PP   P    L  R+ P G   P   AAPP   P   F++ +  +    P   
Sbjct: 947  -------PPRAAPREEPLTPRLKPEGAPEPEGVAAPP---PKNSFNNPAYYVLEGVPHQL 996

Query: 476  RPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADT--------G 527
             PP P SP    +P +  +    T          + +V E  ++   S  T         
Sbjct: 997  LPPEPPSPARAPVPSATKNKVAITVPAPQLGHHRHPRVGEGSSSDEESGGTLPPPDFPPP 1056

Query: 528  LCSEACLF---RLARCPSPKLLRARSAEKRRPVP--TFQKVPLPSGPAPAHS-LGDL 578
               ++ +F    L   P P +     AE R P P     + PLP GP+PA + LG++
Sbjct: 1057 PLPDSAIFLPPSLDPLPGPVVRGRGGAEARGPPPPKAHPRPPLPPGPSPASTFLGEV 1113


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 82/323 (25%), Positives = 118/323 (36%), Gaps = 65/323 (20%)

Query: 210  PERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYN 269
            PE S   P     C SP P    H   +LE+  PP+ P P  PPE               
Sbjct: 828  PEESHLSPQSEEPCLSPRPEES-HLSPELEK--PPLSPRPEKPPEEP------------- 871

Query: 270  GSMDSP--VPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSG 327
            G   +P  +PL+P    PS   ++G     +  L +P     S + E +  +      S 
Sbjct: 872  GQCPAPEELPLFPPPGEPSLSPLLG-----EPALSEPGEPPLSPLPEEL-PLSPSGEPSL 925

Query: 328  SLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFE 387
            S  L     LP   SP   +        +  ++Y          A      +  L  P  
Sbjct: 926  SPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF-------GAKGDSDPESPLAAPIL 978

Query: 388  ESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGG 447
            E+P+   PP A    +C+ PE  PP+  P +  S          VGP  P L   +    
Sbjct: 979  ETPI-SPPPEA----NCTDPEPVPPMILPPSPGSP---------VGPASPILMEPL---- 1020

Query: 448  GRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPP--PLLLPRSHSDPG-ITTSSDTA 504
                  PP  +P  + S        P + PP   SPP  PL +P   S  G +   SD A
Sbjct: 1021 ------PPQCSPLLQHS------LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEA 1068

Query: 505  DFRDLYT-KVLEEEAASVSSADT 526
            +  ++ T KV E E  ++  + T
Sbjct: 1069 ELHEMETEKVSEPECPALEPSAT 1091



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 38/120 (31%), Positives = 46/120 (38%), Gaps = 29/120 (24%)

Query: 382 LRGPFEESP-------LPRRPPRAARSYSC---SAPEAPPPLGAPTAARSCHRLEGWPPW 431
           L  PFEESP       LP  PP  A   S     +P +PPP  +P +          PP 
Sbjct: 545 LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS----------PP- 593

Query: 432 VGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRS 491
                PE  R  P     P + PP  +P     ++S    PP      P SPPP   P S
Sbjct: 594 -----PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP---EDSPMSPPPEESPMS 645



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 37/124 (29%), Positives = 44/124 (35%), Gaps = 7/124 (5%)

Query: 372  AGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPW 431
            AG   S D  L+ P    P P  P           P A  P   P      + LE   P 
Sbjct: 2133 AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVP-AQVPSQDPFGLAPAYPLEPRFPT 2191

Query: 432  VGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSL--TPPGHRPPHPASPPPLLLP 489
              P +P      P   G PA  P   A +R  +   G    TPPG     P++P P L P
Sbjct: 2192 APPTYPPY----PSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKP 2247

Query: 490  RSHS 493
            R  S
Sbjct: 2248 RCPS 2251



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 66/235 (28%), Positives = 84/235 (35%), Gaps = 55/235 (23%)

Query: 410  PPPLG---APTAARSCHRLEGWPPWV--GPCFPELRRRVPRGGG---RPAAAPPTRA--- 458
            PP LG   +P++      LE   P V   P  P   +  P+  G   RP   PP +A   
Sbjct: 2301 PPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP 2360

Query: 459  --PTRRFSDSSGSLTPPGHRPP---HPASPPP----LLLPRS-HSDPGITTSSDTADFRD 508
              P+       GS T P  +PP    P  PPP     L PRS  SDP             
Sbjct: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP------------- 2407

Query: 509  LYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAE----------KRRPVP 558
             +++V      S SS+ + L     L   A CPSP   R +S +           R P  
Sbjct: 2408 -FSRV-PASPQSQSSSQSPLTPRP-LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464

Query: 559  TFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVP 613
               K P P  P  A   G L  +  G G           A  P+G     H +VP
Sbjct: 2465 PLHKPPRPQPPEVAFKAGSLAHTSLGAG--------GFPAALPAGPAGELHAKVP 2511



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 27/128 (21%)

Query: 376 LSLDCGLRGPFEESPL-------PRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGW 428
           L+ +  L  P EESPL       P  PP  A   S   PE  P    P A      LE  
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLS-PPPEELPASPLPEALHLSRPLEES 492

Query: 429 PPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPA-----SP 483
           P              P     P + PP  +P     +S   L+PP   PP PA     SP
Sbjct: 493 P------------LSPPPEESPLSPPPESSPFSPLEESP--LSPPEESPPSPALETPLSP 538

Query: 484 PPLLLPRS 491
           PP   P S
Sbjct: 539 PPEASPLS 546



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 79/320 (24%), Positives = 104/320 (32%), Gaps = 72/320 (22%)

Query: 210 PERSVSGPLGPLGCTSPPPAPL--------LHTMLDLEEFVPPVPPPPYYPPEYTCSSET 261
           PE S + P       SPPP  L        LH    LEE   P+ PPP   P        
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEE--SPLSPPPEESP-----LSP 505

Query: 262 DAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVD 321
             +S  ++   +SP+   P + PPS      L    +A+   P   +             
Sbjct: 506 PPESSPFSPLEESPLSP-PEESPPSPALETPLSPPPEASPLSPPFEESP----------- 553

Query: 322 VSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCG 381
           +S     L  S   +    S P E+S +     S    +  +    + SR          
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPM-----SPPPEESPMSPPPEASR---------- 598

Query: 382 LRGPFEESPL-------PRRPPRAARSYSC---SAPEAPPPLGAPTAAR-SCHRLEGWP- 429
           L  PFEESPL       P  PP  A   S     +P +PPP  +P +      RL   P 
Sbjct: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658

Query: 430 ----------------PWVGPCFP--ELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLT 471
                           P   P  P  E  R  P     P + PP  +P     + S    
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718

Query: 472 PPGHRPPHPASPPPLLLPRS 491
           P    P  P    P L PRS
Sbjct: 719 PLEESPLLPLPEEPQLCPRS 738



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)

Query: 437  PELRRRVPRGGGRPAAAPPTRAPTRRF----------SDSSGSLTPPGHRPPHPASPPPL 486
            P L  R+P   G   + PP  APT             + + G L PP    P P SP  L
Sbjct: 2100 PALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGEL 2159

Query: 487  LLPRSHSDPGITTSSD 502
             L      P    S D
Sbjct: 2160 FLKLPPQVPAQVPSQD 2175



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 36/117 (30%), Positives = 41/117 (35%), Gaps = 24/117 (20%)

Query: 403  SCSAPEAPPP------LGAPTAARSCHRLEGWPPWVGPCFP----ELRRRVPRGGGR--- 449
            S   P  P P      LG+P A  S        P  GP  P    ELR  V +G G    
Sbjct: 2834 SARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGT 2893

Query: 450  --PAAAPPTRAPTRRFSDSSGSLTPPGHR--------PPHPASPP-PLLLPRSHSDP 495
              P   PP R      S+    L P G R        P  P++PP P L    H  P
Sbjct: 2894 PFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 30/101 (29%), Positives = 36/101 (35%), Gaps = 19/101 (18%)

Query: 407  PEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDS 466
            P+ PP L AP  A S        P +GP  P      P+   RP+  P         S S
Sbjct: 4283 PQGPPRLPAPPGALSTG------PVLGPVHPTPPPSSPQEPKRPSQLP---------SPS 4327

Query: 467  SGSLTPPGHRPPHPASP----PPLLLPRSHSDPGITTSSDT 503
            S   T     P HP +P    P L  P     P     +DT
Sbjct: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADT 4368


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 64/243 (26%), Positives = 81/243 (33%), Gaps = 38/243 (15%)

Query: 395 PPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAP 454
           PP    S S S     PP   PT       L   PP     FP +   +P         P
Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN--FPHVTPNLP--------PP 304

Query: 455 PTRAPTRRFSDSS---GSLTPPGHRP-PHPAS------PP-----PLLLPRSHSDPGITT 499
           P   P    S S    G+   PGH P PH         PP     P L P  HS P  ++
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASS 364

Query: 500 SSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPS--PKLLRARSAEKRRPV 557
           S+     R  Y+      AA+ SS+ +   S +        PS         S       
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424

Query: 558 PTFQKVPLPS------GPAPAHSLGDL---KGSWPGRGLVTRFLQISRKAPDPSGTGAHG 608
           P + +  LPS      GP P    G L     + PG    +   Q +  A  P  T  H 
Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST--AHPPVSTHHHH 482

Query: 609 HKQ 611
           H+Q
Sbjct: 483 HQQ 485



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 9/115 (7%)

Query: 374 YCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVG 433
           Y +S   G   P+   P    PP +  SYS + P  PP   +  ++ S  +         
Sbjct: 530 YAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ------GSY 583

Query: 434 PCFPELRRRVPRGGGRPAAAPP---TRAPTRRFSDSSGSLTPPGHRPPHPASPPP 485
           PC      + P+G   P    P   T + T     ++ + +P G++   P  PPP
Sbjct: 584 PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 11/104 (10%)

Query: 402 YSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRG--GGRPAAAPPTRAP 459
           Y  ++P  PPP G    +   ++    P +     P  R   P G  G  P A P T  P
Sbjct: 628 YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP 687

Query: 460 TRRFSDSSGSLTPPG-----HRPPHPASP---PPLLLPRSHSDP 495
               +   G L P G       PP PA+P   PPL   +   +P
Sbjct: 688 GSP-TVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 39/134 (29%), Positives = 46/134 (34%), Gaps = 25/134 (18%)

Query: 392 PRRPPRAARSYSCSAPEAPPPLGA-------PTAARSCHRLEGWPPWV--GPCFPELRRR 442
           P  PP  A     +A  +PP LGA       P+       + G PP    GP        
Sbjct: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358

Query: 443 VPRGGGRPAAAPPTRAPTRRFSD-----SSGSLTPPGHRPPHPAS----------PPPLL 487
           +P      A APP R P    S      SS S +      P PAS          PPP  
Sbjct: 359 LPPASSS-APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417

Query: 488 LPRSHSDPGITTSS 501
           L  S+  P  T  S
Sbjct: 418 LSVSNQPPKYTQPS 431



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 9/93 (9%)

Query: 411 PPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSL 470
           PP+G P    +   + G  P  G   P     +       + APPT+ PT      +   
Sbjct: 231 PPMG-PKGGGAASSVGG--PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPS 287

Query: 471 TPPGHRPPHPA---SPPPLLLP---RSHSDPGI 497
            PP    PH      PPP L P    S S PG+
Sbjct: 288 APPPANFPHVTPNLPPPPALRPLNNASASPPGL 320


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 64/243 (26%), Positives = 81/243 (33%), Gaps = 38/243 (15%)

Query: 395 PPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAP 454
           PP    S S S     PP   PT       L   PP     FP +   +P         P
Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN--FPHVTPNLP--------PP 304

Query: 455 PTRAPTRRFSDSS---GSLTPPGHRP-PHPAS------PP-----PLLLPRSHSDPGITT 499
           P   P    S S    G+   PGH P PH         PP     P L P  HS P  ++
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASS 364

Query: 500 SSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPS--PKLLRARSAEKRRPV 557
           S+     R  Y+      AA+ SS+ +   S +        PS         S       
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424

Query: 558 PTFQKVPLPS------GPAPAHSLGDL---KGSWPGRGLVTRFLQISRKAPDPSGTGAHG 608
           P + +  LPS      GP P    G L     + PG    +   Q +  A  P  T  H 
Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST--AHPPVSTHHHH 482

Query: 609 HKQ 611
           H+Q
Sbjct: 483 HQQ 485



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 9/115 (7%)

Query: 374 YCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVG 433
           Y +S   G   P+   P    PP +  SYS + P  PP   +  ++ S  +         
Sbjct: 530 YAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ------GSY 583

Query: 434 PCFPELRRRVPRGGGRPAAAPP---TRAPTRRFSDSSGSLTPPGHRPPHPASPPP 485
           PC      + P+G   P    P   T + T     ++ + +P G++   P  PPP
Sbjct: 584 PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 11/104 (10%)

Query: 402 YSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRG--GGRPAAAPPTRAP 459
           Y  ++P  PPP G    +   ++    P +     P  R   P G  G  P A P T  P
Sbjct: 628 YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP 687

Query: 460 TRRFSDSSGSLTPPG-----HRPPHPASP---PPLLLPRSHSDP 495
               +   G L P G       PP PA+P   PPL   +   +P
Sbjct: 688 GSP-TVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 39/134 (29%), Positives = 46/134 (34%), Gaps = 25/134 (18%)

Query: 392 PRRPPRAARSYSCSAPEAPPPLGA-------PTAARSCHRLEGWPPWV--GPCFPELRRR 442
           P  PP  A     +A  +PP LGA       P+       + G PP    GP        
Sbjct: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358

Query: 443 VPRGGGRPAAAPPTRAPTRRFSD-----SSGSLTPPGHRPPHPAS----------PPPLL 487
           +P      A APP R P    S      SS S +      P PAS          PPP  
Sbjct: 359 LPPASSS-APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417

Query: 488 LPRSHSDPGITTSS 501
           L  S+  P  T  S
Sbjct: 418 LSVSNQPPKYTQPS 431



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 9/93 (9%)

Query: 411 PPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSL 470
           PP+G P    +   + G  P  G   P     +       + APPT+ PT      +   
Sbjct: 231 PPMG-PKGGGAASSVGG--PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPS 287

Query: 471 TPPGHRPPHPA---SPPPLLLP---RSHSDPGI 497
            PP    PH      PPP L P    S S PG+
Sbjct: 288 APPPANFPHVTPNLPPPPALRPLNNASASPPGL 320


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 8/101 (7%)

Query: 389 SPLPRR---PPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPR 445
           SP P+R   PP+A R  S S P  P   GAP   +        PP  GP  P   R+  +
Sbjct: 551 SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP--GPAGP--TRQASQ 606

Query: 446 GGGRPAAAPP-TRAPTRRFSDSSGSLTPPGHRPPHPASPPP 485
            G  P   PP T+ P       +G   P   + P    PPP
Sbjct: 607 AGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPP 647



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 42/138 (30%), Positives = 51/138 (36%), Gaps = 32/138 (23%)

Query: 384 GPFEESPLPRRPPRAARSYSCSAPEAPPPL--------------GAPTAAR-----SCHR 424
           GP   SPLP+R P    +    A +A PP               GAP AAR     S  R
Sbjct: 497 GPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQR 556

Query: 425 LEGWPPWV-------GPCFPELRRRVPRG---GGRPAAAPPTRAPTRRFSDSS--GSLTP 472
             G PP         GP  P+     P G    G P   P    PTR+ S +       P
Sbjct: 557 QAG-PPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGP 615

Query: 473 PGHRPPHPASPPPLLLPR 490
           P  + P P+ P P   P+
Sbjct: 616 PTTQQPRPSGPGPAGRPK 633


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 8/101 (7%)

Query: 389 SPLPRR---PPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPR 445
           SP P+R   PP+A R  S S P  P   GAP   +        PP  GP  P   R+  +
Sbjct: 551 SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP--GPAGP--TRQASQ 606

Query: 446 GGGRPAAAPP-TRAPTRRFSDSSGSLTPPGHRPPHPASPPP 485
            G  P   PP T+ P       +G   P   + P    PPP
Sbjct: 607 AGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPP 647



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 42/138 (30%), Positives = 51/138 (36%), Gaps = 32/138 (23%)

Query: 384 GPFEESPLPRRPPRAARSYSCSAPEAPPPL--------------GAPTAAR-----SCHR 424
           GP   SPLP+R P    +    A +A PP               GAP AAR     S  R
Sbjct: 497 GPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQR 556

Query: 425 LEGWPPWV-------GPCFPELRRRVPRG---GGRPAAAPPTRAPTRRFSDSS--GSLTP 472
             G PP         GP  P+     P G    G P   P    PTR+ S +       P
Sbjct: 557 QAG-PPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGP 615

Query: 473 PGHRPPHPASPPPLLLPR 490
           P  + P P+ P P   P+
Sbjct: 616 PTTQQPRPSGPGPAGRPK 633


>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 60/214 (28%), Positives = 81/214 (37%), Gaps = 46/214 (21%)

Query: 383 RGPFEESPLPRRPPRAARSYSCSAPEAPPP--------LGAPTAARSCHRLEGWPPWV-- 432
           R P     LP  PPRA       +PE PPP        LGA  AA   HRL      V  
Sbjct: 49  RSPSSRLKLPADPPRALPG----SPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSS 104

Query: 433 -GPCFPELRR--RVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLP 489
            GP   + +R  +  R G R  +A P     R     S   +PP         PPP    
Sbjct: 105 RGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP---------PPPPSRA 155

Query: 490 RSH----SDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKL 545
           RS     S PG    ++ A  R+   ++  ++   +     G C+ A  +  AR    ++
Sbjct: 156 RSRSLRLSAPGSRHDAEKASERN---RLRRKKRLVLGRGGGGECAHAHEWECAR----RM 208

Query: 546 LR-ARSAEKRRPVPT--------FQKVPLPSGPA 570
            R  R+   RRP+ +           VP  SGPA
Sbjct: 209 RRGCRTLTARRPLDSGRGLSPLILAWVPALSGPA 242


>gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
           sapiens]
          Length = 274

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 60/214 (28%), Positives = 81/214 (37%), Gaps = 46/214 (21%)

Query: 383 RGPFEESPLPRRPPRAARSYSCSAPEAPPP--------LGAPTAARSCHRLEGWPPWV-- 432
           R P     LP  PPRA       +PE PPP        LGA  AA   HRL      V  
Sbjct: 49  RSPSSRLKLPADPPRALPG----SPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSS 104

Query: 433 -GPCFPELRR--RVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLP 489
            GP   + +R  +  R G R  +A P     R     S   +PP         PPP    
Sbjct: 105 RGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP---------PPPPSRA 155

Query: 490 RSH----SDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKL 545
           RS     S PG    ++ A  R+   ++  ++   +     G C+ A  +  AR    ++
Sbjct: 156 RSRSLRLSAPGSRHDAEKASERN---RLRRKKRLVLGRGGGGECAHAHEWECAR----RM 208

Query: 546 LR-ARSAEKRRPVPT--------FQKVPLPSGPA 570
            R  R+   RRP+ +           VP  SGPA
Sbjct: 209 RRGCRTLTARRPLDSGRGLSPLILAWVPALSGPA 242


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 66/293 (22%), Positives = 107/293 (36%), Gaps = 45/293 (15%)

Query: 387 EESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPE-------L 439
           + SPL +  P +      + PE P P  +P        L   PP   P  P+       +
Sbjct: 533 QNSPLAKSKPGS------TGPEPPIPQASPGPPGP---LSQTPPMQRPVEPQEGPHKSLV 583

Query: 440 RRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLP-------RSH 492
             RVP    +P AAP  R+ + +   +      P    P PA P P   P       R +
Sbjct: 584 AHRVPL---KPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640

Query: 493 SDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAE 552
           SDP  +     +     + +   E    V    + + +             + +RA + +
Sbjct: 641 SDP-TSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPD 699

Query: 553 KRRPVPTFQKVP--LPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHK 610
            RR  P +++    LP+        G L+ +  G         +S K PD S   + G+K
Sbjct: 700 LRRSDPGWERSDSVLPASHGHLPQAGSLERNRVG---------VSSK-PDSSPVLSPGNK 749

Query: 611 QVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGS 663
             P     RPGR + + R+ G+         LL  R L+   RP   +++  S
Sbjct: 750 AKPDDHRSRPGRPASYKRAIGEDFV------LLKERTLDEAPRPPKKAMDYSS 796


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 16/133 (12%)

Query: 389 SPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVG----PCF-PELRRRV 443
           SP+P+  P         AP   PP   P         +  PP VG    P F P L   +
Sbjct: 641 SPIPKPLPVPVPPIPVPAPITVPPPQVPPH-------QPGPPVVGALQPPAFTPPLG--I 691

Query: 444 PRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASP--PPLLLPRSHSDPGITTSS 501
           P  G  P   PP   P       +    PPG  PP P  P  PP+ +P  H+ P    +S
Sbjct: 692 PPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNS 751

Query: 502 DTADFRDLYTKVL 514
             A   +  TK L
Sbjct: 752 TIAGINEDTTKDL 764



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 219 GPLGCTSPPPAPLLHTMLDLEE----FVPPVPPPPYYPP 253
           GP     PPP P L    +       F+PP PPPP  PP
Sbjct: 697 GPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPP 735


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 16/133 (12%)

Query: 389 SPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVG----PCF-PELRRRV 443
           SP+P+  P         AP   PP   P         +  PP VG    P F P L   +
Sbjct: 656 SPIPKPLPVPVPPIPVPAPITVPPPQVPPH-------QPGPPVVGALQPPAFTPPLG--I 706

Query: 444 PRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASP--PPLLLPRSHSDPGITTSS 501
           P  G  P   PP   P       +    PPG  PP P  P  PP+ +P  H+ P    +S
Sbjct: 707 PPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNS 766

Query: 502 DTADFRDLYTKVL 514
             A   +  TK L
Sbjct: 767 TIAGINEDTTKDL 779



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 219 GPLGCTSPPPAPLLHTMLDLEE----FVPPVPPPPYYPP 253
           GP     PPP P L    +       F+PP PPPP  PP
Sbjct: 712 GPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPP 750


>gi|77681565 NG5 protein [Homo sapiens]
          Length = 306

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 39/114 (34%), Positives = 46/114 (40%), Gaps = 11/114 (9%)

Query: 387 EESPLPRRPPRAARS-YSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPR 445
           E+S LP   P  +   Y+   P A PP   P AA S H                  R+  
Sbjct: 4   EKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHH--HHHYHQSGTATLPRLGA 61

Query: 446 GGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPA--SPPP--LLLPRSHSDP 495
           GG   +AA   R P    S S+    PP H PP PA  +PPP    LPR   DP
Sbjct: 62  GGLASSAATAQRGP----SSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDP 111



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 31/90 (34%), Positives = 33/90 (36%), Gaps = 14/90 (15%)

Query: 373 GYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWV 432
           G   S     RGP   + LPR P  A       A  APPP         C  L   PP  
Sbjct: 63  GLASSAATAQRGPSSSATLPRPPHHAPPG---PAAGAPPP--------GCATLPRMPP-- 109

Query: 433 GPCFPELRRRVPRGGGRP-AAAPPTRAPTR 461
            P   E R   P     P AAAPP  AP +
Sbjct: 110 DPYLQETRFEGPLPPPPPAAAAPPPPAPAQ 139


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,698,941
Number of Sequences: 37866
Number of extensions: 2113500
Number of successful extensions: 16451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 673
Number of HSP's that attempted gapping in prelim test: 12725
Number of HSP's gapped (non-prelim): 3718
length of query: 668
length of database: 18,247,518
effective HSP length: 109
effective length of query: 559
effective length of database: 14,120,124
effective search space: 7893149316
effective search space used: 7893149316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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