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Search of human proteins with 38045890
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
sapiens]
(3667 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 7744 0.0
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 7700 0.0
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 6411 0.0
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 4598 0.0
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 3696 0.0
gi|148886654 polydom [Homo sapiens] 521 e-147
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 410 e-113
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 399 e-110
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 353 2e-96
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 345 5e-94
gi|157419154 selectin P precursor [Homo sapiens] 258 6e-68
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 233 2e-60
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 233 3e-60
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 233 3e-60
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 224 2e-57
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 224 2e-57
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 224 2e-57
gi|22547221 tolloid-like 1 [Homo sapiens] 218 9e-56
gi|6912724 tolloid-like 2 [Homo sapiens] 213 2e-54
gi|187960042 selectin E precursor [Homo sapiens] 206 3e-52
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 202 4e-51
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 199 5e-50
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 194 1e-48
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 193 3e-48
gi|4502503 complement component 4 binding protein, alpha chain p... 176 3e-43
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 146 3e-34
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 145 6e-34
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 134 2e-30
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 128 9e-29
gi|13899255 membrane frizzled-related protein [Homo sapiens] 125 1e-27
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 7744 bits (20092), Expect = 0.0
Identities = 3667/3667 (100%), Positives = 3667/3667 (100%)
Query: 1 MWSWFLCWKPVQLDRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEER 60
MWSWFLCWKPVQLDRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEER
Sbjct: 1 MWSWFLCWKPVQLDRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEER 60
Query: 61 NRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA 120
NRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA
Sbjct: 61 NRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA 120
Query: 121 VSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIA 180
VSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIA
Sbjct: 121 VSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIA 180
Query: 181 NSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTIS 240
NSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTIS
Sbjct: 181 NSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTIS 240
Query: 241 LIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSA 300
LIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSA
Sbjct: 241 LIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSA 300
Query: 301 PYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTS 360
PYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTS
Sbjct: 301 PYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTS 360
Query: 361 LRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFK 420
LRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFK
Sbjct: 361 LRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFK 420
Query: 421 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 480
LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG
Sbjct: 421 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 480
Query: 481 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 540
AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA
Sbjct: 481 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 540
Query: 541 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLH 600
VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLH
Sbjct: 541 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLH 600
Query: 601 LQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEK 660
LQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEK
Sbjct: 601 LQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEK 660
Query: 661 SIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIH 720
SIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIH
Sbjct: 661 SIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIH 720
Query: 721 LSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGR 780
LSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGR
Sbjct: 721 LSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGR 780
Query: 781 GFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDG 840
GFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDG
Sbjct: 781 GFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDG 840
Query: 841 KVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF 900
KVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF
Sbjct: 841 KVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF 900
Query: 901 QTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHY 960
QTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHY
Sbjct: 901 QTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHY 960
Query: 961 ESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL 1020
ESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL
Sbjct: 961 ESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL 1020
Query: 1021 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1080
PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY
Sbjct: 1021 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1080
Query: 1081 LLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLE 1140
LLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLE
Sbjct: 1081 LLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLE 1140
Query: 1141 PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE 1200
PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE
Sbjct: 1141 PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE 1200
Query: 1201 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK 1260
CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK
Sbjct: 1201 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK 1260
Query: 1261 DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP 1320
DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP
Sbjct: 1261 DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP 1320
Query: 1321 QFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1380
QFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG
Sbjct: 1321 QFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1380
Query: 1381 ESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM 1440
ESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM
Sbjct: 1381 ESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM 1440
Query: 1441 LLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRN 1500
LLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRN
Sbjct: 1441 LLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRN 1500
Query: 1501 GDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFIL 1560
GDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFIL
Sbjct: 1501 GDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFIL 1560
Query: 1561 SPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQD 1620
SPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQD
Sbjct: 1561 SPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQD 1620
Query: 1621 SKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLG 1680
SKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLG
Sbjct: 1621 SKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLG 1680
Query: 1681 STVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPK 1740
STVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPK
Sbjct: 1681 STVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPK 1740
Query: 1741 NYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESL 1800
NYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESL
Sbjct: 1741 NYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESL 1800
Query: 1801 PLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSV 1860
PLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSV
Sbjct: 1801 PLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSV 1860
Query: 1861 LFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYD 1920
LFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYD
Sbjct: 1861 LFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYD 1920
Query: 1921 NNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNS 1980
NNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNS
Sbjct: 1921 NNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNS 1980
Query: 1981 TSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQ 2040
TSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQ
Sbjct: 1981 TSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQ 2040
Query: 2041 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWT 2100
GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWT
Sbjct: 2041 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWT 2100
Query: 2101 INLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLY 2160
INLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLY
Sbjct: 2101 INLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLY 2160
Query: 2161 FHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNS 2220
FHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNS
Sbjct: 2161 FHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNS 2220
Query: 2221 ALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNG 2280
ALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNG
Sbjct: 2221 ALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNG 2280
Query: 2281 IYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2340
IYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS
Sbjct: 2281 IYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2340
Query: 2341 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLG 2400
GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLG
Sbjct: 2341 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLG 2400
Query: 2401 ERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFV 2460
ERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFV
Sbjct: 2401 ERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFV 2460
Query: 2461 EFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGF 2520
EFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGF
Sbjct: 2461 EFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGF 2520
Query: 2521 RIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAW 2580
RIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAW
Sbjct: 2521 RIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAW 2580
Query: 2581 DAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2640
DAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW
Sbjct: 2581 DAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2640
Query: 2641 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL 2700
SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL
Sbjct: 2641 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL 2700
Query: 2701 PNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECL 2760
PNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECL
Sbjct: 2701 PNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECL 2760
Query: 2761 SSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD 2820
SSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD
Sbjct: 2761 SSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD 2820
Query: 2821 HNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
HNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ
Sbjct: 2821 HNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
Query: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2940
WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN
Sbjct: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2940
Query: 2941 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 3000
GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH
Sbjct: 2941 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 3000
Query: 3001 WSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG 3060
WSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG
Sbjct: 3001 WSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG 3060
Query: 3061 SWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT 3120
SWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT
Sbjct: 3061 SWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT 3120
Query: 3121 WSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT 3180
WSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT
Sbjct: 3121 WSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT 3180
Query: 3181 WSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
WSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS
Sbjct: 3181 WSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
Query: 3241 GEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGS 3300
GEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGS
Sbjct: 3241 GEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGS 3300
Query: 3301 SPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS 3360
SPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS
Sbjct: 3301 SPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS 3360
Query: 3361 GIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWT 3420
GIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWT
Sbjct: 3361 GIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWT 3420
Query: 3421 GKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTS 3480
GKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTS
Sbjct: 3421 GKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTS 3480
Query: 3481 FNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGF 3540
FNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGF
Sbjct: 3481 FNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGF 3540
Query: 3541 VSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFF 3600
VSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFF
Sbjct: 3541 VSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFF 3600
Query: 3601 ALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNL 3660
ALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNL
Sbjct: 3601 ALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNL 3660
Query: 3661 NTVCTMV 3667
NTVCTMV
Sbjct: 3661 NTVCTMV 3667
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 7700 bits (19979), Expect = 0.0
Identities = 3653/3666 (99%), Positives = 3653/3666 (99%), Gaps = 1/3666 (0%)
Query: 3 SWFLCWKPV-QLDRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN 61
S F W V L GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN
Sbjct: 42 SGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN 101
Query: 62 RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV 121
RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV
Sbjct: 102 RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV 161
Query: 122 SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 181
SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN
Sbjct: 162 SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 221
Query: 182 SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 241
SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL
Sbjct: 222 SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
Query: 242 IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP 301
IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP
Sbjct: 282 IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP 341
Query: 302 YQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSL 361
YQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSL
Sbjct: 342 YQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSL 401
Query: 362 RNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKL 421
RNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKL
Sbjct: 402 RNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKL 461
Query: 422 FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA 481
FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA
Sbjct: 462 FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA 521
Query: 482 KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAV 541
KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAV
Sbjct: 522 KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAV 581
Query: 542 NTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHL 601
NTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHL
Sbjct: 582 NTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHL 641
Query: 602 QTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKS 661
QTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKS
Sbjct: 642 QTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKS 701
Query: 662 IVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHL 721
IVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHL
Sbjct: 702 IVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHL 761
Query: 722 SFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG 781
SFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG
Sbjct: 762 SFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG 821
Query: 782 FNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGK 841
FNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGK
Sbjct: 822 FNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGK 881
Query: 842 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 901
VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ
Sbjct: 882 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 941
Query: 902 TELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYE 961
TELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYE
Sbjct: 942 TELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYE 1001
Query: 962 SVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLP 1021
SVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLP
Sbjct: 1002 SVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLP 1061
Query: 1022 TCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYL 1081
TCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYL
Sbjct: 1062 TCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYL 1121
Query: 1082 LITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEP 1141
LITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEP
Sbjct: 1122 LITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEP 1181
Query: 1142 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC 1201
CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC
Sbjct: 1182 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC 1241
Query: 1202 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1261
GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD
Sbjct: 1242 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1301
Query: 1262 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQ 1321
KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQ
Sbjct: 1302 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQ 1361
Query: 1322 FGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGE 1381
FGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGE
Sbjct: 1362 FGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGE 1421
Query: 1382 SSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDML 1441
SSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDML
Sbjct: 1422 SSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDML 1481
Query: 1442 LKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNG 1501
LKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNG
Sbjct: 1482 LKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNG 1541
Query: 1502 DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILS 1561
DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILS
Sbjct: 1542 DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILS 1601
Query: 1562 PNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDS 1621
PNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDS
Sbjct: 1602 PNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDS 1661
Query: 1622 KLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGS 1681
KLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGS
Sbjct: 1662 KLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGS 1721
Query: 1682 TVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKN 1741
TVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKN
Sbjct: 1722 TVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKN 1781
Query: 1742 YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLP 1801
YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLP
Sbjct: 1782 YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLP 1841
Query: 1802 LSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVL 1861
LSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVL
Sbjct: 1842 LSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVL 1901
Query: 1862 FDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDN 1921
FDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDN
Sbjct: 1902 FDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDN 1961
Query: 1922 NLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNST 1981
NLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNST
Sbjct: 1962 NLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNST 2021
Query: 1982 SNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQG 2041
SNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQG
Sbjct: 2022 SNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQG 2081
Query: 2042 YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTI 2101
YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTI
Sbjct: 2082 YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTI 2141
Query: 2102 NLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYF 2161
NLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYF
Sbjct: 2142 NLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYF 2201
Query: 2162 HSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSA 2221
HSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSA
Sbjct: 2202 HSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSA 2261
Query: 2222 LTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2281
LTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI
Sbjct: 2262 LTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2321
Query: 2282 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSG 2341
YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSG
Sbjct: 2322 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSG 2381
Query: 2342 FFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE 2401
FFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE
Sbjct: 2382 FFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE 2441
Query: 2402 RLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVE 2461
RLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVE
Sbjct: 2442 RLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVE 2501
Query: 2462 FFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2521
FFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR
Sbjct: 2502 FFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2561
Query: 2522 IRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2581
IRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD
Sbjct: 2562 IRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2621
Query: 2582 APVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2641
APVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS
Sbjct: 2622 APVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2681
Query: 2642 NHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLP 2701
NHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLP
Sbjct: 2682 NHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLP 2741
Query: 2702 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLS 2761
NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLS
Sbjct: 2742 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLS 2801
Query: 2762 SGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH 2821
SGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH
Sbjct: 2802 SGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH 2861
Query: 2822 NWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQW 2881
NWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQW
Sbjct: 2862 NWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQW 2921
Query: 2882 SHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG 2941
SHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG
Sbjct: 2922 SHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG 2981
Query: 2942 QWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 3001
QWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW
Sbjct: 2982 QWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 3041
Query: 3002 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 3061
SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS
Sbjct: 3042 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 3101
Query: 3062 WTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTW 3121
WTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTW
Sbjct: 3102 WTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTW 3161
Query: 3122 SGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW 3181
SGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW
Sbjct: 3162 SGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW 3221
Query: 3182 SGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSG 3241
SGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSG
Sbjct: 3222 SGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSG 3281
Query: 3242 EVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSS 3301
EVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSS
Sbjct: 3282 EVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSS 3341
Query: 3302 PHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSG 3361
PHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSG
Sbjct: 3342 PHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSG 3401
Query: 3362 IQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTG 3421
IQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTG
Sbjct: 3402 IQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTG 3461
Query: 3422 KVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSF 3481
KVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSF
Sbjct: 3462 KVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSF 3521
Query: 3482 NASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFV 3541
NASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFV
Sbjct: 3522 NASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFV 3581
Query: 3542 SAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFA 3601
SAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFA
Sbjct: 3582 SAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFA 3641
Query: 3602 LIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLN 3661
LIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLN
Sbjct: 3642 LIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLN 3701
Query: 3662 TVCTMV 3667
TVCTMV
Sbjct: 3702 TVCTMV 3707
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 6411 bits (16633), Expect = 0.0
Identities = 3074/3271 (93%), Positives = 3110/3271 (95%), Gaps = 83/3271 (2%)
Query: 406 HRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 465
++VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG
Sbjct: 342 YQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 401
Query: 466 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 525
STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP
Sbjct: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
Query: 526 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 585
FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF
Sbjct: 462 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 521
Query: 586 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 645
VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV
Sbjct: 522 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 581
Query: 646 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 705
LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL
Sbjct: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 641
Query: 706 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 765
NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH
Sbjct: 642 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 701
Query: 766 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 825
ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI
Sbjct: 702 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 761
Query: 826 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 885
KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI
Sbjct: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 821
Query: 886 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 945
EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF
Sbjct: 822 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 881
Query: 946 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 1005
TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE
Sbjct: 882 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 941
Query: 1006 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV
Sbjct: 942 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
Query: 1066 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1125
QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI
Sbjct: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1061
Query: 1126 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1185
SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG
Sbjct: 1062 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1121
Query: 1186 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1245
GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART
Sbjct: 1122 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1181
Query: 1246 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1305
FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV
Sbjct: 1182 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1241
Query: 1306 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY
Sbjct: 1242 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1301
Query: 1366 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1425
PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS
Sbjct: 1302 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1361
Query: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485
HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA
Sbjct: 1362 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1421
Query: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI
Sbjct: 1422 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1481
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY
Sbjct: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
Query: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1665
DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG
Sbjct: 1542 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1601
Query: 1666 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1725
NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR
Sbjct: 1602 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1661
Query: 1726 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1785
STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS
Sbjct: 1662 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1721
Query: 1786 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1845
SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR
Sbjct: 1722 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1781
Query: 1846 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1905
FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK
Sbjct: 1782 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1841
Query: 1906 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1965
RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR
Sbjct: 1842 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1901
Query: 1966 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 2025
LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG
Sbjct: 1902 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 1961
Query: 2026 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2085
DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP
Sbjct: 1962 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2021
Query: 2086 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2145
GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ
Sbjct: 2022 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2081
Query: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT 2205
IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT
Sbjct: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT 2141
Query: 2206 ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN 2265
ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN
Sbjct: 2142 ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN 2201
Query: 2266 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2325
FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST
Sbjct: 2202 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2261
Query: 2326 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2385
SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP
Sbjct: 2262 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2321
Query: 2386 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA 2445
GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA
Sbjct: 2322 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA 2381
Query: 2446 WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV 2505
WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSP V
Sbjct: 2382 WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSP---------------------V 2420
Query: 2506 FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK 2565
+ S D+ + + I+ G ++ ++W+ D G G
Sbjct: 2421 LISLSGDYSS----------------------AFNITSNGHEV--FLQWSADHGNNKKGF 2456
Query: 2566 SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILT-TDYLVGTRVTYFCNDGYRL 2624
A C P++P +G I++ T + + V + C+ G+RL
Sbjct: 2457 RIRYI------------------AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRL 2498
Query: 2625 SSKELTTAVCQ--SDGTWSNHNKTPRCVVVTC----PSINSFILEHGRWRIVNGSHYEYK 2678
K ++AVC+ S G + P C ++C N IL + Y
Sbjct: 2499 VGK--SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILT---------TDYLVG 2547
Query: 2679 TKVVFSCDPGYHGLGP--ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTS 2736
T+V + C+ GY + C +GTWS N+ P C +ISCGELPTPPNGNKIGTQTS
Sbjct: 2548 TRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTS 2607
Query: 2737 YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYR 2796
YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYR
Sbjct: 2608 YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYR 2667
Query: 2797 DTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDV 2856
DTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDV
Sbjct: 2668 DTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDV 2727
Query: 2857 VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2916
VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG
Sbjct: 2728 VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2787
Query: 2917 TVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGST 2976
TVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGST
Sbjct: 2788 TVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGST 2847
Query: 2977 VHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKS 3036
VHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKS
Sbjct: 2848 VHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKS 2907
Query: 3037 TVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSS 3096
TVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSS
Sbjct: 2908 TVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSS 2967
Query: 3097 VIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS 3156
VIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS
Sbjct: 2968 VIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS 3027
Query: 3157 YMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSIS 3216
YMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSIS
Sbjct: 3028 YMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSIS 3087
Query: 3217 YICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFS 3276
YICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFS
Sbjct: 3088 YICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFS 3147
Query: 3277 CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQ 3336
CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQ
Sbjct: 3148 CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQ 3207
Query: 3337 FHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIY 3396
FHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIY
Sbjct: 3208 FHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIY 3267
Query: 3397 TCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFA 3456
TCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFA
Sbjct: 3268 TCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFA 3327
Query: 3457 QNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRI 3516
QNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRI
Sbjct: 3328 QNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRI 3387
Query: 3517 YLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEG 3576
YLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEG
Sbjct: 3388 YLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEG 3447
Query: 3577 SNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAA 3636
SNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAA
Sbjct: 3448 SNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAA 3507
Query: 3637 FENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3667
FENPMYDTNAKSVEGKAVRFDPNLNTVCTMV
Sbjct: 3508 FENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
Score = 1280 bits (3312), Expect = 0.0
Identities = 783/2181 (35%), Positives = 1137/2181 (52%), Gaps = 124/2181 (5%)
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+ TCG L+G +GT SP FP+ Y + A C WVI A N+ IQI F+ F LE YD L+
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLS 120
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
+ DG P LTG +P + S S L L +D +V + GFKV Y+E++ SC
Sbjct: 121 LYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN----QWSANIPICIF- 679
G+PG P G+ G F D +R+ C G+ L G + C N+ W +PIC
Sbjct: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 680 -PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 738
C G + SP +P Y NN +C WTI+++PG I L F DF +E ++D+L ++
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
Query: 739 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY------------ 786
+ P +G +P + SN + LRL F D + RGF+ Y
Sbjct: 299 GSEPPTI----WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRG 354
Query: 787 ----------NTF----------GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIK 826
N F N CPDPG P N +R G +F LGS++ C+E ++
Sbjct: 355 FKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV- 413
Query: 827 TQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCEWV 884
QG ++ITC + + WS P C CG + PSG SP +P Y + C WV
Sbjct: 414 LQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWV 473
Query: 885 IEA-EPGHSIKITFERFQTELNYDVLEVHDGPNLLSP--LLGSYNGTQVPQFLFSSSNFI 941
I A I+I FE F E+ YD L + DG + P +L G+ VP + S S+ +
Sbjct: 474 ITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQM 533
Query: 942 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYR 1001
+L TD S + GFK++Y+ + SC DPG P++G R G FS + F C G+
Sbjct: 534 WLHLQTDESVGSVGFKVNYKE--IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 591
Query: 1002 LSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH 1061
L E+ ++C++N+ WS +P C C + P GT+LSP YPE Y N+LNC WT+
Sbjct: 592 LIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDP 651
Query: 1062 GKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFI 1120
G + +F+ F LE D+L + + S P L TG+++P + + + +L F
Sbjct: 652 GSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTS---NSHILRLEFQ 708
Query: 1121 SDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGTSE 1179
+D S+S GFNIT++ + C DPGIP R G NF +G +++ C G+ + +GT
Sbjct: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTET 768
Query: 1180 IIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKG 1238
I C L G+ +WS +P+C A CG + G++LSP +P Y+++ C + I+ + G
Sbjct: 769 ITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
Query: 1239 INISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1297
I I+ F DVL+++DG + + LLG++ G + L S+SN ++L F +D
Sbjct: 829 IKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQF-LFSSSNFIYLLFTTDNSR 887
Query: 1298 TDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGH--FAGSTIIYGCNPGYTLHGSSLL 1353
++ GF++ Y S ++ C DPGIP G + GH GST+ + C+ GY L L
Sbjct: 888 SNNGFKIHYESVTVNTYSCLDPGIPVHGRR---YGHDFSIGSTVSFSCDSGYRLSHEEPL 944
Query: 1354 KCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIV 1413
C + W +PLP+C A CGG +G SG ILSPGYP Y N+L C W ++V G V
Sbjct: 945 LC--EKNHWWSHPLPTCDALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
Query: 1414 SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFDTDFY 1470
F F E HD L + + L + ++GS +P I++ L ++F +DF
Sbjct: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPLAR-LTGSDLPPTINAGLYGNFRAQLRFISDFS 1060
Query: 1471 ISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQ 1530
IS GF I FS C DPG+P G+R G GDT+ F C GY L+G I C+
Sbjct: 1061 ISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1120
Query: 1531 VENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAF 1590
R W P C+A CG + T + G +LSPN+P Y ++ +C ++I V A I+++
Sbjct: 1121 -GGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISA 1179
Query: 1591 ISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVSYTGF 1649
+F + D L IYDG D + L+G+F + + + S+SN + L F SD + GF
Sbjct: 1180 RTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGF 1238
Query: 1650 HLEYKAKLRESCFDPGNIMNGTRLG-MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGR 1708
L Y + C DPG G ++ + GST+ Y C+ GY L G S L C+ G+ R
Sbjct: 1239 QLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGE--R 1296
Query: 1709 PGWNRALPSCHAPCGSRSTG-SEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFF 1767
W+ LPSC A CG R G S G +LSP YP Y C++ I V +V QF+ F
Sbjct: 1297 RAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAF 1356
Query: 1768 QT-SLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFV 1826
T + HD++ V+DGP + LL +SGS E + S+ N +TI+F + I+ GF
Sbjct: 1357 DTEASHDILRVWDGPPENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQ 1415
Query: 1827 YQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLA 1886
+ + + +T C P G R G+ G +V+F C+PGY L G I C V N
Sbjct: 1416 FSS---SVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF 1472
Query: 1887 QWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFAT 1946
W S P CI PCGG LT G ILSP +P PY ++ +C W ITV I + +SF+
Sbjct: 1473 -WQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSI 1531
Query: 1947 EHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2006
E N+D L YDG D+N+P +GS+ + +P + S+SN ++L F+SD SVS GFHLEY A
Sbjct: 1532 EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
Query: 2007 IGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYPI 2064
+SC +P +G ++G Y +G V++ CD GY LQG+S +TC+ G R WN +
Sbjct: 1592 KLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1651
Query: 2065 PICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDY 2124
P C A CG + G +LSP +P NY +C ++I +P F V QFV F T ++HD
Sbjct: 1652 PSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT-SLHDV 1710
Query: 2125 LEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY---- 2179
+EV G ++ S+++ LSG SL S+ ++ ++ F S +GFH VYQA
Sbjct: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
Query: 2180 --QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNHP 2235
Q S P+PR R IGN+F VG ++ F+C PGY L G+ A+ C + WN
Sbjct: 1771 STQCSSVPEPRFGRR---IGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1827
Query: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD 2295
LP C CGG +T GTI SPGYP+ Y N +C W + VP G GI + TE +D
Sbjct: 1828 LPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWD 1887
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLRV 2354
+ +DG D N+P++G +SG T + STSN + + F SD + S F L Y A L
Sbjct: 1888 SLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDS 1947
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
C P P P++ I D + +GD++ +QC G++L G++ +TC G + + P+C
Sbjct: 1948 C-PEPQTPSSGIKI-GDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
Query: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
C D +GVILSPG+P +YP+ C W+I++ G+ + + F TE D L+V
Sbjct: 2006 QC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
Query: 2475 YDGPNIQSPVLISLSGDY--SSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---C 2529
G + S V+ LSG SS F+ T HE L + +D+ NK+GF I Y A+ C
Sbjct: 2064 RSGSSETSTVIGRLSGPQIPSSLFSTT---HETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
Query: 2530 STPESPPHGYIISQ--TGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
P +G++I T GQ + + C G+ L+G S+ C W+ P+P C
Sbjct: 2121 PDPRPFRNGFVIGNDFTVGQ---TISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRC 2175
Query: 2588 QAISCGIPKAPTNGGILTTDY 2608
+A+ CG NG I + Y
Sbjct: 2176 EAL-CGGNITAMNGTIYSPGY 2195
Score = 1077 bits (2786), Expect = 0.0
Identities = 859/2907 (29%), Positives = 1253/2907 (43%), Gaps = 325/2907 (11%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
I+ C GT+ SP +P GY N NC W II++ +RI + F F LE ++D+L++
Sbjct: 614 IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 673
Query: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
DG + TG +P +TS + L +D ++S GF + Y + C +P
Sbjct: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 733
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
G+P +G F +G I C G+I G +TCI W +P C A
Sbjct: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMD-GKVMWSGLIPKCGA--P 790
Query: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 260
CGG SG+I SP +P Y ++ +C W I AEPG +I + F FQ E YD LE+
Sbjct: 791 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 850
Query: 261 ----EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 316
P +G +P + S+ N++ L F TD++ GF Y+ + T++
Sbjct: 851 PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 910
Query: 317 LEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLS 376
+ H R ++ ST S + + +RLS E+ + + + P + D L
Sbjct: 911 IPVHGRRYGHDFSIGST------VSFSCDSGYRLSHEEPL-LCEKNHWWSHPLPTCDALC 963
Query: 377 ----PHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFS 432
P+ T + P VTH K + F F L ++ + +
Sbjct: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH--GKGVQFNFHTFHL----EDHHDYL 1017
Query: 433 ILNEGGI-------KTASNLCPDPGEPENGK-----RIGSDFSL---------------- 464
++ E G T S+L P G R SDFS+
Sbjct: 1018 LITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEP 1077
Query: 465 ---------GSTVQF----------SCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
GS + F SC Y L+G I C + WS P C V
Sbjct: 1078 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC--LGGGRRVWSAPLPRC-V 1134
Query: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 565
CG++ G SPN+P Y++N +C++ I V K I I+ F L G D L I
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSI-QVQAGKGINISARTFHLAQG-DVLKI 1192
Query: 566 GDGGEVGDPRTVLQVLTGSFVPDL-IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
DG + +L TG+ + L + S S+Q+WL +D GF++ Y E C
Sbjct: 1193 YDGKD--KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHC 1250
Query: 625 GDPGTPLYGIREGD-GFSNRDVLRFECQFGFELIGEKSIVCQ--ENNQWSANIPICIFPC 681
DPG P +G + D G + + C G+ L G + C E W +P CI C
Sbjct: 1251 EDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1310
Query: 682 LSNFTA-PMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 740
F G +LSP YP Y NNL C+W I DPG+ + L F FD E+ D L V DG
Sbjct: 1311 GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG 1370
Query: 741 DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 800
+L +G+ +P + S +I+ ++F D +S GF I +++ C DPG+P
Sbjct: 1371 PPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1430
Query: 801 INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFS 860
+N R GD + G ++ C+ G+ + QG E ITCI ++ + W P C APCGG+ +
Sbjct: 1431 MNGTRNGDGREPGDTVVFQCDPGY-ELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1489
Query: 861 APSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP 920
SG ILSP +P Y S +C+W I + I + F F E NYD L ++DGP+ SP
Sbjct: 1490 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1549
Query: 921 LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGR 980
L+GS+ +++P+ + SSSN ++L F +D S S GF + Y++ SC DPG ++G
Sbjct: 1550 LIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL--RESCFDPGNIMNGT 1607
Query: 981 RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRGPSG 1036
R G D+ +GSTV++ CD+GY L L C + W+ LP+C A CG G G
Sbjct: 1608 RLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEG 1667
Query: 1037 TILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI----TENGSFTQP 1092
T+LSP YP+ Y NC +++ V + V F F HD + + T+ S
Sbjct: 1668 TVLSPNYPKNYSVGHNCVYSIAVPK-EFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSS 1726
Query: 1093 LA-RLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS---EYNLEPCEDPGIP 1148
L+ +G LP L + +RF S I+ +GF+ + + C P
Sbjct: 1727 LSGSHSGESLP------LSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEP 1780
Query: 1149 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC--LGGGRRVWSAPLPRCVAECGASAT 1206
++G RIG F +G ++ F C+ GY L G+ I C + W+ LP C+ CG T
Sbjct: 1781 RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILT 1840
Query: 1207 NNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-DVLKIYDGKDKTTH 1265
+G +LSP YP Y+NN C++ I V G GI + +F D L YDG D
Sbjct: 1841 KRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAP 1900
Query: 1266 LLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYK 1325
LG+++G ++ L L+STSN L+L F SD + GF L YT+ L C +P P G K
Sbjct: 1901 RLGSYSGTTIPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIK 1959
Query: 1326 ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGR 1385
I D+ + G + + C+ GY+L G S + CM G R W+YP+P C+A+CGG + SG
Sbjct: 1960 IGDR-YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM-SDFSGV 2017
Query: 1386 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEI 1445
ILSPG+P Y ++L C W I + G V LQF+ F TE HD L V G E ++ +
Sbjct: 2018 ILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRL 2077
Query: 1446 SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGRE 1505
SG IP + ST + ++ F +D+ +K GF I + + +C DP NG G+
Sbjct: 2078 SGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFT 2137
Query: 1506 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1565
G T+ F+C PGY L G +TC+ +R W P C A CGGN+T +G I SP +P
Sbjct: 2138 VGQTISFECFPGYTLIGNSALTCLHGVSRN-WNHPLPRCEALCGGNITAMNGTIYSPGYP 2196
Query: 1566 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1625
YP+ +DC W + V I + F EP YDF+ ++DGPD NSP IG F + E
Sbjct: 2197 DEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALE 2256
Query: 1626 RIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD--YKLGSTV 1683
+ S+SN + + F SD + S F L Y A C P + N L D +++G +
Sbjct: 2257 SVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDII 2315
Query: 1684 TYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRS--TGSEGTVLSPNYPKN 1741
Y C G+ L G + LTC +G+ R + A P C C + S G +LSP YP +
Sbjct: 2316 RYQCLPGFTLVGNAILTCRLGE--RLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2373
Query: 1742 YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLH-DVVEVYDGPTQQSSLLSSLSGSHSGESL 1800
Y C +SI+V K + + FFQT DV++VYDGP QS +L SLSG +S
Sbjct: 2374 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Query: 1801 PLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFA-VGSS 1859
S+G+++ +++++ KGF Y A CS+ P G I + S
Sbjct: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAF------YCSTPESPPHGYIISQTGGQLNSV 2487
Query: 1860 VLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEP 1918
V + C+ G+ L G + C W+ +P C + CG G IL+ Y
Sbjct: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYL-- 2545
Query: 1919 YDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLL 1978
+ +V F N+ RL S TT
Sbjct: 2546 ------------------VGTRVTYFC---------------NDGYRLSSKELTTAVCQS 2572
Query: 1979 NSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQC 2038
+ T +N H + + SC E TP +G KIG + G F C
Sbjct: 2573 DGTWSN----------------HNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTC 2616
Query: 2039 DQGYSLQGHSHITCMPGPVRRWNYPIPICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDC 2097
D G+ L G + C+ + W+ CLA CG +G ++ + C
Sbjct: 2617 DLGFMLVGSAVRECLSSGL--WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQC 2674
Query: 2098 TWTINLPIGFGVHL--QFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTH 2155
L IG V + Q N+S + + + V G S + GR SG + T
Sbjct: 2675 NPGFRL-IGSSVRICQQDHNWSGQ-LPSCVPVSCG-HPGSPIYGRTSGNGFNFNDVVTFS 2731
Query: 2156 ETSLYF-----HSDYSQNKQGFHIVYQAYQLQSCPDP----RPFRNGFVIGNDFTVGQTI 2206
Y + N+Q H ++ +C DP R + +FT G +
Sbjct: 2732 CNIGYLMQGPTKAQCQANRQWSHPPPMC-KVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2790
Query: 2207 SFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPN 2265
++C PGY L G+S L C + W+ PLP C + CG PG P PN
Sbjct: 2791 FYDCNPGYFLFGSSVLIC--QPNGQWDKPLPECIMIDCG-----------HPGVP---PN 2834
Query: 2266 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2325
VL E TV +GQ S L +S
Sbjct: 2835 --------------------AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 2874
Query: 2326 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2385
S H +G C P + ++ F +RY C
Sbjct: 2875 SQP-----HCSGDATG------------TCGDPGTPGHGS--RQESNFRTKSTVRYACDT 2915
Query: 2386 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE--------LRLD----STGVILS-- 2431
G+ L G+ TC G P C+ + N R+D S+ VI S
Sbjct: 2916 GYILHGSEERTCLANG--SWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCM 2973
Query: 2432 PGYPDSYPNLQMC----AWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLIS 2487
GY S P+++ C WS ++ N T+ + + L+ D + V
Sbjct: 2974 EGYILSGPSVRQCTANGTWSGTLP---NCTI-ISCGDPGIPANGLRYGDDYVVGQNVSYM 3029
Query: 2488 LSGDYSSAFN------ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYII 2541
Y+ N T NG WS G A C TP +G +
Sbjct: 3030 CQPGYTMELNGSRIRTCTING-----TWS--------GVMPTCRAVTCPTPPQISNGR-L 3075
Query: 2542 SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG 2601
T + + C G+ L + C G W VP C CG P P G
Sbjct: 3076 EGTNFDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKFCGDPGIPAQG 3131
Query: 2602 GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI-NSF 2660
++ + V++ CN + L +T +CQ+DGTWS +P C+ T S N
Sbjct: 3132 KREGKSFIYQSEVSFSCNFPFILVGS--STRICQADGTWS--GSSPHCIEPTQTSCENPG 3187
Query: 2661 ILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2720
+ HG N ++ + V F C G+ G + CLP+ TWS +P C SC
Sbjct: 3188 VPRHGSQN--NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS--GIQPECIPHSCK 3243
Query: 2721 ELPTPPNGNKIGTQ-TSYGSTAIFTCDLGFMLVGSAV-RECLSSGLWSESETRCLAGH-- 2776
+ TP + N +G S+G T I+TC GF L G R C S W+ C AG
Sbjct: 3244 QPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKI 3303
Query: 2777 ----------CGIPELIVNGQVIGENY 2793
P+L V V +NY
Sbjct: 3304 LVKDPRPALGTPSPKLSVPDDVFAQNY 3330
Score = 841 bits (2172), Expect = 0.0
Identities = 702/2408 (29%), Positives = 1008/2408 (41%), Gaps = 366/2408 (15%)
Query: 1201 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-DVLKIYDG 1259
CG + G + SP +P Y N C + I + I I ++F L + D L +YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 1260 KDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGI 1319
T+ TG + ++ST + L SD + GF++ Y + S C +PG+
Sbjct: 125 HPHPTNFRTRLTGFHLPP-PVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGV 183
Query: 1320 PQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTG--ERRAWDYPLPSCIAE--CG 1375
P G + G I Y C GY L G L C+ +WD+P+P C AE CG
Sbjct: 184 PPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 242
Query: 1376 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
G +G SSG I SP +P Y NN C W I +PG+ +SL F F E +D L +
Sbjct: 243 GTMRG-SSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSE 301
Query: 1436 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGF--------AIQFSS----- 1482
P L SG IP I S N + + F TD GF AI F S
Sbjct: 302 PPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKL 357
Query: 1483 -------------------SVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1523
+ + C DPG P NG R G G TV F CD Y LQG
Sbjct: 358 FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA 417
Query: 1524 ERITCIQVENRY-FWQPSPPVC-IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTIT-V 1580
+ ITC ++ + W PVC + CG NL G SG SPNFP Y + C W IT V
Sbjct: 418 KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAV 477
Query: 1581 NADYVISLAFISFSIEPNYDFLYIYDGPDSNSP------LIGSFQDSKLPERIESSSNTM 1634
N + VI + F F +E YD L I DG + P L GSF +P+ I S S+ M
Sbjct: 478 NTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF----VPDLIVSMSSQM 533
Query: 1635 HLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQ 1694
L ++D SV GF + YK +ESC DPG + G R G + + + C G+ L
Sbjct: 534 WLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELI 593
Query: 1695 GYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYS-IA 1753
G ++ C + W+ +P C PC S T GTVLSP+YP+ Y NC+++ I+
Sbjct: 594 GEKSIVCQENNQ----WSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIIS 649
Query: 1754 VPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFT 1813
P + F S D + V DG + +S +L + +G+ L S+ + + + F
Sbjct: 650 DPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHL-TSNSHILRLEFQ 708
Query: 1814 SVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYI-LHG 1872
+ ++ +GF+ Y +C P RR G+ F +GSS+ C G+I G
Sbjct: 709 ADHSMSGRGFNITYNTF---GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQG 765
Query: 1873 SIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVP 1932
+ I C + + W+ +P C PCGG + G ILSPG+P Y ++LNC W I
Sbjct: 766 TETITC-ILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAE 824
Query: 1933 EGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSD 1992
G I++ F TE N+D L+ +DG + +P LGSY+GT +P L S+SN +YL F +D
Sbjct: 825 PGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 884
Query: 1993 ISVSAAGFHLEYTAIGLD--SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHI 2050
S S GF + Y ++ ++ SC +P P G + G + +G VSF CD GY L +
Sbjct: 885 NSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPL 944
Query: 2051 TCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVH 2110
C W++P+P C A CGG + SG ILSPG+P YP+SL+CTWT+++ G GV
Sbjct: 945 LCEKN--HWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQ 1002
Query: 2111 LQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTH---ETSLYFHSDYSQ 2167
F F E HDYL + S T + RL+G +P ++ + + L F SD+S
Sbjct: 1003 FNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1061
Query: 2168 NKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHG 2227
+ +GF+I + Y L+ C DP + G IG +F +G T++F C GY L G S + CL G
Sbjct: 1062 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1121
Query: 2228 VSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV 2287
R W+ PLPRC A CG + T G + SP YP Y N +C + ++V G GI I+
Sbjct: 1122 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1181
Query: 2288 LQTEPIYDFITVWDGPDQNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFT-TSGFFVL 2345
D + ++DG D+ + +G F+G + ++ STSNQ+ ++F+SD T F L
Sbjct: 1182 FHLAQ-GDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQL 1240
Query: 2346 SYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQM 2405
Y +++L C+ P +P D G I Y C PG+TL G+++L C GER
Sbjct: 1241 VYTSFELSHCE-DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAW 1299
Query: 2406 DGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQT 2465
D P C C + +S+G ILSPGYP Y N C W I V+ G +++ F T
Sbjct: 1300 DYPLPSCIAEC-GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDT 1358
Query: 2466 EKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY- 2524
E D+L+V+DGP +L +SG I S + V +Q+ D +K GF I++
Sbjct: 1359 EASHDILRVWDGPPENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFS 1417
Query: 2525 --IAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2582
+A C P P +G + G + V + CD G+ L G+ C + Y W
Sbjct: 1418 SSVATACRDPGVPMNG-TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF-WQP 1475
Query: 2583 PVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFC------NDGYRLSSKELTTAVCQS 2636
P C A CG ++G IL+ ++ + C N Y +S ++ ++ +
Sbjct: 1476 SPPVCIA-PCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN 1534
Query: 2637 -------DGTWSN--------HNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKV 2681
DG SN +K P + + +++ G G H EYK K+
Sbjct: 1535 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVS-YTGFHLEYKAKL 1593
Query: 2682 VFSC-DPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGST 2740
SC DPG NG ++G GST
Sbjct: 1594 RESCFDPG-----------------------------------NIMNGTRLGMDYKLGST 1618
Query: 2741 AIFTCDLGFMLVGSAVRECLSSG----LWSESETRCLAGHCGIPELIVNGQVIGENYGYR 2796
+ CD G++L G + C+ W+ + C A CG G V+ NY
Sbjct: 1619 VTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKN 1677
Query: 2797 DTVVYQCNPG------------FRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG 2844
+V + C F +S+ + ++ Q S + G
Sbjct: 1678 YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLP 1737
Query: 2845 RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKR 2904
+SGN I + GP A + P CS P +R
Sbjct: 1738 LSSGN----------QITIRFTSVGPITA--KGFHFVYQAVPRTSSTQCSSVPEPRFGRR 1785
Query: 2905 ESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQ--PN--GQWDKPLPECIMIDCG---- 2956
F G+ V +DCNPGY L GS + C+ PN QW+ LP CI + CG
Sbjct: 1786 IG----NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI-VPCGGILT 1840
Query: 2957 -------HPG----------------VPPNAVLSGEKYTFGSTVH--------------- 2978
PG VP A + + +F +T H
Sbjct: 1841 KRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF-ATEHNWDSLDFYDGGDNNA 1899
Query: 2979 -----YSCTGKRSLLGQSSRTCQLNGH----WSGSQPHCSGDATG--TCGDPGTPGHGSR 3027
YS T LL +S LN S + H A G +C +P TP G +
Sbjct: 1900 PRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIK 1959
Query: 3028 QESNFRTKSTVRYACDTGYILHGSEERTCLAN--GSWTGRQPECKAVQCG---------- 3075
+ V + CD GY L G TC+ W P C A QCG
Sbjct: 1960 IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA-QCGGAMSDFSGVI 2018
Query: 3076 -NPGTTAN---------------GKVFRIDGTTFSSSVIYSCMEGYI-----------LS 3108
+PG N G + FS+ I+ +E LS
Sbjct: 2019 LSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLS 2078
Query: 3109 GPSVRQCTANGTWSGTL-----------------PNCTIISCGDPGIPANGLRYGDDYVV 3151
GP + + T +L + SC DP NG G+D+ V
Sbjct: 2079 GPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2138
Query: 3152 GQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAVTCPTPPQISNGRLEGTNF 3209
GQ +S+ C PGYT L G+ TC ++ W+ +P C A + G + N
Sbjct: 2139 GQTISFECFPGYT--LIGNSALTCLHGVSRNWNHPLPRCEA--------LCGGNITAMN- 2187
Query: 3210 DWGFSISYICSPGYELSFPAVLTCV-------GNG------------------TWSG--- 3241
I SPGY +P C GNG W G
Sbjct: 2188 ------GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQ 2241
Query: 3242 EVPQCLPKFCGDPGIPAQGKREGKSFI-YQSEVSFSCNFPFILVGSSTRICQADGTWSGS 3300
PQ + +F G+ + + + I + S+ + S F R+CQ
Sbjct: 2242 NSPQ-IGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPP------ 2294
Query: 3301 SPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL--PDLT 3358
P VP F++G ++++ C G L G+ TC L
Sbjct: 2295 --------------PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ 2340
Query: 3359 WSGIQPEC 3366
G P C
Sbjct: 2341 MDGAPPVC 2348
Score = 608 bits (1567), Expect = e-173
Identities = 289/302 (95%), Positives = 289/302 (95%), Gaps = 1/302 (0%)
Query: 3 SWFLCWKPV-QLDRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN 61
S F W V L GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN
Sbjct: 42 SGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN 101
Query: 62 RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV 121
RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV
Sbjct: 102 RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV 161
Query: 122 SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 181
SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN
Sbjct: 162 SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 221
Query: 182 SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 241
SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL
Sbjct: 222 SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
Query: 242 IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP 301
IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP
Sbjct: 282 IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP 341
Query: 302 YQ 303
YQ
Sbjct: 342 YQ 343
Score = 189 bits (480), Expect = 4e-47
Identities = 105/288 (36%), Positives = 149/288 (51%), Gaps = 13/288 (4%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLS 80
+ TCG L+G +GT SP FP+ Y + A C WVI A N+ IQI F+ F LE YD L+
Sbjct: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
Query: 81 LYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
+ DG P LTG +P + S S L L +D +V + GFKV Y+E++ SC
Sbjct: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
Query: 139 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
G+PG P G+ G F D +R+ C G+ L G + C N+ W +PIC
Sbjct: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN----QWSANIPICIF- 615
Query: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
C G + SP +P Y NN +C WTI+++PG I L F DF +E ++D+L ++
Sbjct: 616 -PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
Query: 259 GSEPPTI----WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
+ P +G +P + SN + LRL F D + RGF+ Y
Sbjct: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 722
Score = 174 bits (442), Expect = 1e-42
Identities = 103/318 (32%), Positives = 155/318 (48%), Gaps = 44/318 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGGT++G +G I SP FP Y N A+CTW I+AE + I ++F F +EE+YDYL +
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE------------- 131
P PT + L+G ++PPP+ S K+ L +D GF Y+
Sbjct: 301 EP-PTIW---LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
Query: 132 -------------------ELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDG 172
+ S+ C +PG P G G+ F +G +++SC Y+L G
Sbjct: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
Query: 173 HPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIV 232
+TC + A+W P+C+ + CG ++G SG +SP+FP +Y +NA C W I
Sbjct: 417 AKSITCQRIAEVFAAWSDHRPVCKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT 475
Query: 233 A-EPGDTISLIFTDFQMEEKYDYLEI----EGSEPPTIW--LSGMNIPPPIISNKNWLRL 285
A I + F +F +E YD L I E +P T+ L+G +P I+S + + L
Sbjct: 476 AVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWL 535
Query: 286 HFVTDSNHRYRGFSAPYQ 303
H TD + GF Y+
Sbjct: 536 HLQTDESVGSVGFKVNYK 553
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 4598 bits (11927), Expect = 0.0
Identities = 2075/3301 (62%), Positives = 2592/3301 (78%), Gaps = 23/3301 (0%)
Query: 370 TSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 429
+SK+ L H + RR+ +A+ +VKKAI+ KSRG K+ P KD S+
Sbjct: 285 SSKNWLRLHFTSDSNHRRKGFNAQ------------FQVKKAIELKSRGVKMLPSKDGSH 332
Query: 430 KFSILNEGGIKTASNLCPDPGEPENGKRIGSDFS-LGSTVQFSCDEDYVLQGAKSITCQR 488
K S+L++GG+ S++CPDPG PENG+R GSDFS +G+ VQFSC+++YVLQG+KSITCQR
Sbjct: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
Query: 489 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 548
+ E AAWSDHRP+C+ +TCGSNL+GPSG TSPN+P QY+ NA CVWVIT + +KVI+
Sbjct: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIK 452
Query: 549 INFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVG 608
+ FEEF+LE GYDTLT+GD G+VGD R+VL VLTGS VPDLIVSMS+QMWLHLQ+D+S+G
Sbjct: 453 LAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIG 512
Query: 609 SVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN 668
S GFK Y+EIEK CGDPG P YG R G F + D L FEC FEL+GE+ I CQ+NN
Sbjct: 513 SPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN 572
Query: 669 QWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDL 728
QWS N P C+F C NFTA G +LSP+YPE YGNN+NC+W IIS+PGSRIHL FNDFD+
Sbjct: 573 QWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDV 632
Query: 729 ESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
E QFDFLAVKD + +LGTF+G EVPS L S+ HI+RLEFQ+DHS +GRGFNITY T
Sbjct: 633 EPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
Query: 789 FGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 848
FG NEC DPGIPIN RRFGD F LGSS+S C++GF+KTQG+E+ITCIL DG V+WS +
Sbjct: 693 FGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTV 752
Query: 849 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 908
P+C APCGGH +A SGVIL PGWPGYYKDSL+CEW+IEA+PGHSIKITF+RFQTE+NYD
Sbjct: 753 PRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDT 812
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
LEV DGP SPL+G Y+GTQ PQFL S+ NF+YLLFTTDNSRS+ GF IHYESVT+ +
Sbjct: 813 LEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESD 872
Query: 969 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 1028
SCLDPGIPV+G R+G DF I STV+FSCD GY LS +EPL+CE+NH W+H LP+CDALCG
Sbjct: 873 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG 932
Query: 1029 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGS 1088
G ++G SGT+LSPG+P+FYPNSLNCTWT++V+HGKGVQ FHTFHLE HDYLLITE+GS
Sbjct: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGS 992
Query: 1089 FTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIP 1148
F++P+ARLTGS LP TI AGL+GNF AQLRFISDFSISYEGFNITFSEY+LEPC+DPG+P
Sbjct: 993 FSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVP 1052
Query: 1149 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNN 1208
+ RIGF+FG+GD+LTFSC GYRLEG +++ CLGGGRRVWSAPLPRCVAECGAS N
Sbjct: 1053 AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGN 1112
Query: 1209 EGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLG 1268
EG LLSPN+P NY+NNHECIY I+ +AGKGI++ R+F L +GD LK+YDGKD ++ LG
Sbjct: 1113 EGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLG 1172
Query: 1269 AFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISD 1328
FT + GL L+STSN LWLEFN++ TD+GFQL YTSF+L CEDPGIP +GY+I D
Sbjct: 1173 TFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRD 1232
Query: 1329 QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILS 1388
+GHF + ++Y CNPGY +HGS+ L C++G+RR WD PLPSCIAECGG+ +SGRILS
Sbjct: 1233 EGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILS 1292
Query: 1389 PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS 1448
PGYP PYDNNL C W+IE DPG +SL F+ FDTE +HDIL+VWDGP ++D+LLKE SGS
Sbjct: 1293 PGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGS 1352
Query: 1449 LIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGD 1508
+PE IHST N +T+QFD+DF+ISKSGF+IQFS+S+A C DPG+P NGTR GD RE GD
Sbjct: 1353 ALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGD 1412
Query: 1509 TVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPY 1568
TV FQCDPGY+LQG+ +ITC+Q+ NR+FWQP PP CIA CGGNLTG +G ILSPN+P PY
Sbjct: 1413 TVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPY 1472
Query: 1569 PHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE 1628
P ++CDW + VN D+VI+L F SF++EP+YDFL+IY+G DSNSPLIGS+Q S+ PERIE
Sbjct: 1473 PPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIE 1532
Query: 1629 SSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCD 1688
SS N++ LAFRSD SV +GF +E+K K RE+CFDPGNIMNGTR+G D+KLGST+TY CD
Sbjct: 1533 SSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCD 1592
Query: 1689 AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC 1748
+GY + S++TC++G DG+P W++ LPSC+APCG + TGSEG VLSPNYP NY+ G C
Sbjct: 1593 SGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQIC 1652
Query: 1749 VYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI 1808
+YSI VPKEFVVFGQF +FQT+L+D+ E++DG Q+ LLSSLSGSHSGE+LPL++ NQI
Sbjct: 1653 LYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQI 1712
Query: 1809 TIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGY 1868
+RF++ +A+GFHFVYQAVPRTS TQCSSVPEPR+GRRIG+EF+ GS V F+CNPGY
Sbjct: 1713 LLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGY 1772
Query: 1869 ILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWK 1928
+L GS A+ C++VPN+LAQWND++P+C+VPC G T+R+GTILSPGYPEPY NNLNC+WK
Sbjct: 1773 LLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWK 1832
Query: 1929 ITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLN 1988
I V EG+GIQ+QV+SFATE NWDSL+ +DGGD APRLGS+SGTT+P LLNSTSN LYL+
Sbjct: 1833 IIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLH 1892
Query: 1989 FQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 2048
FQSDISV+AAGFHLEY +GL +C EP PS+ IKIGDRYMV DV+SFQC+ GY+LQG S
Sbjct: 1893 FQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRS 1952
Query: 2049 HITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFG 2108
HI+CMPG VRRWNYP P+C+A CGG +S GVILSPGFPG+YP++LDCTW I+LPIG+G
Sbjct: 1953 HISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYG 2012
Query: 2109 VHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQN 2168
H+QF+NFSTE HD+LE+++G TS +IG+ SG +P++L STTHET ++F+SD+SQN
Sbjct: 2013 AHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQN 2072
Query: 2169 KQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGV 2228
+QGF + YQAY+LQ+CPDP PF+NG++I +D++VGQ++SFEC+PGY LIG+ LTC HG+
Sbjct: 2073 RQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGI 2132
Query: 2229 SRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL 2288
+RNWN+P PRC+A CG N+T+ NGTIYSPG+PDEYP +DC WL+ VPPG+G+YINFT+L
Sbjct: 2133 NRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL 2192
Query: 2289 QTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYH 2348
QTE + D+I VWDGPDQNSPQ+G FSGNTALE+ YS++NQ+L+KFHSDF+ GFFVL++H
Sbjct: 2193 QTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFH 2252
Query: 2349 AYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA 2408
A+QL+ CQPPP VP AE+LTEDD+FEIGD ++YQC PG+TLVG ILTC+L +LQ +G+
Sbjct: 2253 AFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGS 2312
Query: 2409 PPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE 2468
P C+ CPANE+R S+GVILSPGYP +Y N Q C+WSI VE YNIT+FV+ FQ+EK+
Sbjct: 2313 LPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ 2372
Query: 2469 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2528
FD L+V+DG + QSP+L+ LSG+++ N TS ++++L+WS DH +KKGF+IRY A Y
Sbjct: 2373 FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPY 2432
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
CS +G I+++T G + S V + C G+R+VG S+A CR++ G + WD+ P CQ
Sbjct: 2433 CSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQ 2492
Query: 2589 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2648
A+SCGIP++P NG ++ + ++V Y C++G++L S + TAVCQ DG WSN K P
Sbjct: 2493 AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
Query: 2649 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2708
C V CPSI + + EH WR+V+GS EY +V+ SC PGY+ G + C NGTW+
Sbjct: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
Query: 2709 NERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2768
+ERP C++ISCG L PPNGNKIGT T YG+TAIFTC+ G+ LVGS VRECL++GLWS S
Sbjct: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGS 2672
Query: 2769 ETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLP 2828
ETRCLAGHCG P+ IVNG + G+ + YRDTVVYQCNPGFRL+G+SVRIC QDH WSGQ P
Sbjct: 2673 ETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTP 2732
Query: 2829 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2888
CVP++CGHPG+P +G T+G+ FN NDVV F+CN GYL+QG ++AQC++N QWS P P C
Sbjct: 2733 VCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2792
Query: 2889 KVVNCSDPGIPANSKRESKIEH-GNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPL 2947
+VVNCSDPG N+ R + +F YG + Y C G++L GSS L C NG WD+ L
Sbjct: 2793 RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSL 2852
Query: 2948 PECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPH 3007
P+C+ I CGHPGVP NAVL+GE +T+G+ VHYSC G SL+G +R CQ + HWSG+ PH
Sbjct: 2853 PKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPH 2912
Query: 3008 CSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP 3067
C+G+ G CGDPGTP HGSR +F+TKS +R++C+ G+ L GS ERTCL NGSW+G QP
Sbjct: 2913 CTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQP 2972
Query: 3068 ECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPN 3127
C+AV CGNPGT NG + DG FSSSVIY+C EGY SG R CTANGTW+GT P+
Sbjct: 2973 VCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPD 3032
Query: 3128 CTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPT 3187
CTIISCGDPG ANG+++G D+ + VSY C PGY ME S CT +G W+ P
Sbjct: 3033 CTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPV 3092
Query: 3188 CRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL 3247
C+AV CP PP + NG +EG++F WG SISY C GY+LS A+L+C G G W GE+PQCL
Sbjct: 3093 CKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL 3152
Query: 3248 PKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEP 3307
P FCGDPGIPA+G+ GKSF Y+SEV F C PFILVGSS R+CQADGTWSG P CI+P
Sbjct: 3153 PVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDP 3212
Query: 3308 TQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI 3367
+C +PG P G QN++ G++VGS V F C+KG+ +QGSTTRTCL +LTWSGIQ ECI
Sbjct: 3213 AHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECI 3272
Query: 3368 PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3427
PH+C+QPETPAHA+V +DLP+ GYTL+YTC PGFFLAGG+EHR C++D WTGK P+C+
Sbjct: 3273 PHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
Query: 3428 AGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGR 3487
+ K R T + K VP DVF N +WKG Y + G++QP TLTV FNA++ +
Sbjct: 3333 S------KGVREVNETVT-KTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSSK 3385
Query: 3488 VNATLSN-SNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPD 3546
VNAT S S +EL L+G+YK +EA L+L+ + IK A V K + +NW +DG+VS+ +
Sbjct: 3386 VNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGLE 3445
Query: 3547 GATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAG 3606
+ FQG I GKD+G+F L+R ++ +SS+ HGT+S SVA AILVPFFALI +G
Sbjct: 3446 RGGFTFQGDIHGKDFGKFKLERQD-PLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSG 3504
Query: 3607 FGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTM 3666
F FYLYK RT PK QY G + HEN+NGQA+FENPMYDTN K E KAVRFD LNTVCT+
Sbjct: 3505 FAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTV 3564
Query: 3667 V 3667
V
Sbjct: 3565 V 3565
Score = 1716 bits (4443), Expect = 0.0
Identities = 1058/3156 (33%), Positives = 1548/3156 (49%), Gaps = 228/3156 (7%)
Query: 443 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
S+ C +PGE G G+ F++G +++SC Y+L+G +TC A+W P
Sbjct: 142 SHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
Query: 503 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
C+ + CG L+G S + +SP+FP +Y++NA C W I A I + F +F LE GYD
Sbjct: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA-EPGDTIALVFTDFQLEEGYD 260
Query: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 618
L E+ LTG +P ++S + + LH +D + GF + K
Sbjct: 261 FL------EISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKA 314
Query: 619 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDV-LRF 648
IE +S C DPG P G R G FS ++F
Sbjct: 315 IELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQF 374
Query: 649 ECQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGN 703
C+ + L G KSI CQ + WS + PIC C SN P G + SP+YP Y +
Sbjct: 375 SCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYED 434
Query: 704 NLNCIWTI-ISDPGSRIHLSFNDFDLESQFDFLAVKD----GDSPESPILGTFTGAEVPS 758
N +C+W I +DP I L+F +F+LE +D L V D GD+ +L TG+ VP
Sbjct: 435 NAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDT--RSVLYVLTGSSVPD 492
Query: 759 HLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISV 818
+ S S+ + L Q+D S+ GF Y C DPGIP +R G +F G +++
Sbjct: 493 LIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTF 552
Query: 819 ICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS 878
C F + G ITC WSG P C C +F+A SG+ILSP +P Y ++
Sbjct: 553 ECPAAF-ELVGERVITC---QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNN 608
Query: 879 LNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSS 938
+NC W+I +EPG I + F F E +D L V D +LG+++G +VP L SS
Sbjct: 609 MNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSG 668
Query: 939 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDS 998
+ + L F +D+S + GF I Y T C DPGIP++GRR+G F +GS+VSF CD
Sbjct: 669 HIVRLEFQSDHSTTGRGFNITY--TTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDD 726
Query: 999 GY-RLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCT 1054
G+ + E + C + N WS +P C+A CGG + SG IL PG+P +Y +SL+C
Sbjct: 727 GFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCE 786
Query: 1055 WTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNF 1113
W ++ G ++ F F E ++D L + + + + PL G+ P + + GNF
Sbjct: 787 WIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIS--TGNF 844
Query: 1114 RAQLRFISDFSISYEGFNITFSEYNLE--PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSG 1171
L F +D S S GF I + LE C DPGIP G R G +FGI T+TFSC G
Sbjct: 845 -MYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPG 903
Query: 1172 YRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSI 1231
Y L ++C W+ LP C A CG G +LSP +P Y N+ C ++I
Sbjct: 904 YTLSDDEPLVC--ERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI 961
Query: 1232 QVQAGKGINISARTFHL-AQGDVLKIYDG---KDKTTHLLGAFTGASMRGLTLSSTSNQL 1287
+V GKG+ + TFHL + D L I + + L G+ +++ + + Q
Sbjct: 962 EVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQ- 1020
Query: 1288 WLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHF-AGSTIIYGCNPGYT 1346
L F SD + EGF + ++ ++L C+DPG+P F +I HF G ++ + C GY
Sbjct: 1021 -LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIG--FHFGVGDSLTFSCFLGYR 1077
Query: 1347 LHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIE 1406
L G++ L C+ G RR W PLP C+AECG KG + G +LSP +P YDNN C++ IE
Sbjct: 1078 LEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG-NEGTLLSPNFPSNYDNNHECIYKIE 1136
Query: 1407 VDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEIS-GSLIPEGIHSTLNIVTIQF 1465
+ G + L+ +F D L+V+DG + L + L+ ++ST N + ++F
Sbjct: 1137 TEAGKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEF 1195
Query: 1466 DTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVV-FQCDPGYELQGEE 1524
+T+ + GF + ++S C DPG+P G R D DTVV + C+PGY + G
Sbjct: 1196 NTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSN 1255
Query: 1525 RITCIQVENRYFWQPSPPVCIAPCGGNL-TGSSGFILSPNFPHPYPHSRDCDWTITVNAD 1583
+TC+ + R W P CIA CGG + +SG ILSP +P PY ++ C W I +
Sbjct: 1256 TLTCLSGDRR-VWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPG 1314
Query: 1584 YVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS 1643
ISL FI F E +D L ++DGP + L+ + S LPE I S+ N++ L F SD
Sbjct: 1315 KTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFF 1374
Query: 1644 VSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIM 1703
+S +GF +++ + +C DPG NGTR G + G TVT+ CD GY LQG + +TC+
Sbjct: 1375 ISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQ 1434
Query: 1704 GDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1763
++ R W P+C A CG TG G +LSPNYP+ Y G C + + V +FV+
Sbjct: 1435 LNN-RFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALI 1493
Query: 1764 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1822
F F +D + +Y+G S L+ S GS + E + SSGN + + F S + G
Sbjct: 1494 FKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIE-SSGNSLFLAFRSDASVGLSG 1552
Query: 1823 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1882
F ++ PR + C G R+G +F +GS++ + C+ GY + +I C
Sbjct: 1553 FAIEFKEKPREA---CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGA 1609
Query: 1883 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1942
+ W+ LP+C PCGG T +G +LSP YP Y C++ ITVP+ + Q
Sbjct: 1610 DGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFA 1669
Query: 1943 SFATEHNWDSLDFYDGGDNNAPRL----GSYSGTTIPHLLNSTSNNLYLNFQSDISVSAA 1998
F T N D + +DG A L GS+SG T+P +TSN + L F + SA
Sbjct: 1670 YFQTALN-DLAELFDGTHAQARLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASAR 1725
Query: 1999 GFHLEYTAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC--M 2053
GFH Y A+ S C P G +IG + G +V F+C+ GY LQG + + C +
Sbjct: 1726 GFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSV 1785
Query: 2054 PGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQF 2113
P + +WN IP C+ C G + G ILSPG+P Y ++L+C W I + G G+ +Q
Sbjct: 1786 PNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQV 1845
Query: 2114 VNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFH 2173
++F+TE D LE+ G T+ +G SG +P+ L ST+++ L+F SD S GFH
Sbjct: 1846 ISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFH 1905
Query: 2174 IVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWN 2233
+ Y+ L +C +P N IG+ + V +SF+C PGYTL G S ++C+ G R WN
Sbjct: 1906 LEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWN 1965
Query: 2234 HPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2293
+P P C A CGG ++ + G I SPG+P YPN DC W + +P G G +I F TE
Sbjct: 1966 YPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN 2025
Query: 2294 YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQL 2352
+DF+ + +GP SP IGQFSG ++ ST+++ LI F+SD + + F L+Y AY+L
Sbjct: 2026 HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYEL 2085
Query: 2353 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2412
+ C PPP N ++ D + +G + ++C PG+ L+G+ +LTC+ G + P C
Sbjct: 2086 QNCPDPPPFQNGYMINSD--YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Query: 2413 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2472
C N G I SPG+PD YP L+ C W I+V G+ + + QTE D +
Sbjct: 2144 DAPCGYNV--TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYI 2201
Query: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---C 2529
V+DGP+ SP L SG+ ++ S+ ++V L++ +D N F + + AF C
Sbjct: 2202 AVWDGPDQNSPQLGVFSGN-TALETAYSSTNQVLLKFHSDFSNG-GFFVLNFHAFQLKKC 2259
Query: 2530 STPESPPHGYIISQTGG-QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
P + P ++++ ++ V++ C G+ LVG C+ SS ++ +P C+
Sbjct: 2260 QPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS--QLQFEGSLPTCE 2317
Query: 2589 AISCGIPKAPT--NGGILTTDY----------------LVGTRVTYFCN----------- 2619
A C + T +G IL+ Y +T F +
Sbjct: 2318 A-QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDAL 2376
Query: 2620 ----------------DGYRLSSKELTTAVCQSDGTWSNHNKT-----------PRCVVV 2652
G T+ Q WS + T P C +
Sbjct: 2377 EVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYC-SL 2435
Query: 2653 TCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL--PNGTWSWRNE 2710
T P N IL + + HY C PGY +G ++ C P G + W +
Sbjct: 2436 THPLKNGGILNRTAGAVGSKVHY--------FCKPGYRMVGHSNATCRRNPLGMYQWDSL 2487
Query: 2711 RPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGS--AVRECLSSGLWSE- 2767
P CQ +SCG +P NG+ G + + S ++ C GF L S A C GLWS
Sbjct: 2488 TPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNK 2547
Query: 2768 ------SETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH 2821
C + + E ++ V G Y V+ C+PG+ L G + CQ +
Sbjct: 2548 GKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANG 2607
Query: 2822 NWS--GQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR 2879
W+ + PSC +SCG P G G + F+CN GY + G +C AN
Sbjct: 2608 TWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANG 2667
Query: 2880 QWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQP 2939
WS C +C P N I F+Y V Y CNPG+ L G+SV IC
Sbjct: 2668 LWSGSETRCLAGHCGSPDPIVN----GHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQ 2723
Query: 2940 NGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 2999
+ +W P C+ I CGHPG P + +G ++ V+++C L G S C+ NG
Sbjct: 2724 DHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNG 2783
Query: 3000 HWSGSQPHCSGDATGTCGDPG----TPGHGSRQ-ESNFRTKSTVRYACDTGYILHGSEER 3054
WS P C C DPG HG + +F ++ Y C G+ L GS
Sbjct: 2784 QWSSPLPTC---RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSAL 2840
Query: 3055 TCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQ 3114
TC+ANG W P+C A+ CG+PG AN V + T+ + V YSC L G R
Sbjct: 2841 TCMANGLWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVVHYSCRGSESLIGNDTRV 2899
Query: 3115 CTANGTWSGTLPNCTIIS---CGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSR 3171
C + WSG LP+CT + CGDPG PA+G R GDD+ + + C+ G+ +L GS
Sbjct: 2900 CQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGH--QLRGSP 2957
Query: 3172 IRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN-FDWGFSISYICSPGYELSFPAV 3230
RTC +NG+WSG+ P C AV+C P +NG + ++ + S+ Y C GY+ S
Sbjct: 2958 ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMT 3017
Query: 3231 LTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFIL--VGSST 3288
C NGTW+G P C CGDPG A G + G F + VS+ CN +++ V S+T
Sbjct: 3018 RHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSAT 3077
Query: 3289 RICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGS 3348
C DG W+ S P C C P ++G+ + F+ GS + + C G+ L S
Sbjct: 3078 IRCTKDGRWNPSKPVC---KAVLCPQPPPVQNGTVEGS-DFRWGSSISYSCMDGYQLSHS 3133
Query: 3349 TTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGT 3408
+C W G P+C+P C P PA + G ++ + + C+ F L G+
Sbjct: 3134 AILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSF-TYKSEVFFQCKSPFILV-GS 3191
Query: 3409 EHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTP 3444
RVC++D TW+G P C + DP GTP
Sbjct: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDP----GTP 3223
Score = 1487 bits (3849), Expect = 0.0
Identities = 998/3079 (32%), Positives = 1480/3079 (48%), Gaps = 216/3079 (7%)
Query: 504 KVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTL 563
K + CG +QGP+GT SP FP Y + A C W+I N+ IQ++F F LE +D L
Sbjct: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
Query: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
++ DG V L+G +P IVS S + L TD +V + GFK Y+ + +
Sbjct: 87 SVYDGQPQQGNLKVR--LSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
Query: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPICIF 679
CG+PG L G+ G F+ D +R+ C G+ L G + C W P C
Sbjct: 145 CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
Query: 680 P--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 737
C ++ SP +P Y NN +C WTI+++PG I L F DF LE +DFL +
Sbjct: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
Query: 738 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN---------- 787
++P TG +PS + S+ + LRL F +D + +GFN +
Sbjct: 265 SGTEAPSI----WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
Query: 788 ----------------------TFGHNECPDPGIPINARRFGDNF-QLGSSISVICEEGF 824
+ CPDPGIP N RR G +F ++G+++ CE+ +
Sbjct: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNY 380
Query: 825 IKTQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCE 882
+ QG+++ITC + + WS P C A CG + PSGVI SP +P Y+D+ +C
Sbjct: 381 V-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Query: 883 WVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNL--LSPLLGSYNGTQVPQFLFSSSN 939
WVI +P IK+ FE F+ E YD L V D + +L G+ VP + S SN
Sbjct: 440 WVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
Query: 940 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 999
++L +D+S + GFK Y+ + C DPGIP +G+R G F G T++F C +
Sbjct: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKG--GCGDPGIPAYGKRTGSSFLHGDTLTFECPAA 557
Query: 1000 YRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV 1059
+ L E + C++N+ WS P+C C + SG ILSP YPE Y N++NC W +
Sbjct: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
Query: 1060 THGKGVQFNFHTFHLEDHHDYLLITENG-SFTQPLARLTGSDLPPTINAGLYGNFRAQLR 1118
G + F+ F +E D+L + ++G S L +G+++P + + +L
Sbjct: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIVRLE 674
Query: 1119 FISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGT 1177
F SD S + GFNIT++ + C DPGIP G R G F +G +++F C G+ + +G+
Sbjct: 675 FQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGS 734
Query: 1178 SEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAG 1236
I C L G VWS+ +PRC A CG T + G++L P +P Y+++ C + I+ + G
Sbjct: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
Query: 1237 KGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDT 1295
I I+ F D L++ DG ++ L+G + G L ST N ++L F +D
Sbjct: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQF-LISTGNFMYLLFTTDN 853
Query: 1296 EGTDEGFQLVYTS--FELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSL 1352
+ GF + Y S E C DPGIP G++ G F ST+ + C+PGYTL
Sbjct: 854 SRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEP 911
Query: 1353 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1412
L C + W++ LPSC A CGG +G+ SG +LSPG+P Y N+L C W IEV G
Sbjct: 912 LVCERNHQ--WNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHGKG 968
Query: 1413 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL---NIVTIQFDTDF 1469
V + F F E+SHD L + + ++ + + ++GS++P I + L ++F +DF
Sbjct: 969 VQMIFHTFHLESSHDYLLITEDGSFSEPVAR-LTGSVLPHTIKAGLFGNFTAQLRFISDF 1027
Query: 1470 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCI 1529
IS GF I FS C DPGVP R G GD++ F C GY L+G ++TC+
Sbjct: 1028 SISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCL 1087
Query: 1530 QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1589
R W P C+A CG ++ G+ G +LSPNFP Y ++ +C + I A I L
Sbjct: 1088 G-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLR 1146
Query: 1590 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI-ESSSNTMHLAFRSDGSVSYTG 1648
SF + D L +YDG DS+S +G+F ++L I S+SN + L F ++GS + G
Sbjct: 1147 TRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQG 1205
Query: 1649 FHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYY-CDAGYVLQGYSTLTCIMGDDG 1707
F L Y + C DPG G R+ + TV Y C+ GY + G +TLTC+ GD
Sbjct: 1206 FQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD-- 1263
Query: 1708 RPGWNRALPSCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVF 1766
R W++ LPSC A CG + + G +LSP YP Y +C + I + F+
Sbjct: 1264 RRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIV 1323
Query: 1767 FQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHF 1825
F T + HD+++V+DGP LL SGS E + S+ N +T++F S I+ GF
Sbjct: 1324 FDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSGFSI 1382
Query: 1826 VYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1885
+ + + C+ P+ G R G+ G +V F C+PGY L G I C + N
Sbjct: 1383 QFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRF 1439
Query: 1886 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFA 1945
W PTCI CGG LT G ILSP YP+PY C W++ V I + SF
Sbjct: 1440 F-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
Query: 1946 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 2005
E ++D L Y+G D+N+P +GSY G+ P + S+ N+L+L F+SD SV +GF +E+
Sbjct: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
Query: 2006 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYP 2063
++C +P +G ++G + +G +++QCD GY + S ITC+ G + W+
Sbjct: 1559 EKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQV 1618
Query: 2064 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2123
+P C A CGG + GV+LSP +P NY + C ++I +P F V QF F T ++D
Sbjct: 1619 LPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALND 1677
Query: 2124 YLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY--- 2179
E+ G+ + ++ LSG +L +T+++ L F + + +GFH VYQA
Sbjct: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
Query: 2180 ---QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNH 2234
Q S P+PR R IG++F+ G + FEC PGY L G++AL C + WN
Sbjct: 1738 SDTQCSSVPEPRYGRR---IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
Query: 2235 PLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY 2294
+P C C GN T GTI SPGYP+ Y N +C W + V G+GI I TE +
Sbjct: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
Query: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLR 2353
D + + DG D +P++G FSG T + STSNQ+ + F SD + + F L Y L
Sbjct: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
Query: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
CQ P N+ + D + + D++ +QC PG+TL G + ++C G + + P+C
Sbjct: 1915 ACQEPALPSNS--IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2473
C L GVILSPG+P SYPN C W IS+ GY + F TE D L+
Sbjct: 1973 ATCGGTLSTLG--GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
Query: 2474 VYDGPNIQSPVLISLSG-DYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYC-ST 2531
+ +GP SP++ SG D +A + S HE + + +DH N++GF++ Y A+ +
Sbjct: 2031 IQNGPYHTSPMIGQFSGTDLPAA--LLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
Query: 2532 PESPP--HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHA-WDAPVPACQ 2588
P+ PP +GY+I+ + + V + C G+ L+G C+ +G + W+ P P C
Sbjct: 2089 PDPPPFQNGYMIN-SDYSVGQSVSFECYPGYILIGHPVLTCQ---HGINRNWNYPFPRCD 2144
Query: 2589 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2648
A CG NG I + + D Y + K+ + G H
Sbjct: 2145 A-PCGYNVTSQNGTIYSPGF----------PDEYPI-LKDCIWLITVPPG----HGVYIN 2188
Query: 2649 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL-------P 2701
++ ++N +I + +G VFS + ++ + L
Sbjct: 2189 FTLLQTEAVNDYI------AVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 2242
Query: 2702 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVREC 2759
NG + N + Q+ C P P + + G + C G+ LVG+ + C
Sbjct: 2243 NGGFFVLNFHAF-QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTC 2301
Query: 2760 -LSSGLWSESETRCLAGHCGIPELIV--NGQVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2816
LSS L E C E+ +G ++ Y C+ ++ +
Sbjct: 2302 KLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNIT 2361
Query: 2817 CQQDHNWSGQLPSCVPVSCGHPG-SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC 2875
D S + + V G G SP+ SGN ++ + S N YL A
Sbjct: 2362 IFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRS-NQLYLRWSTDHATS 2420
Query: 2876 QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL 2935
+ + + P C + + G N + G+ V Y C PGY + G S
Sbjct: 2421 KKGFKIRYAAPYCSLTHPLKNGGILNRTAGA--------VGSKVHYFCKPGYRMVGHSNA 2472
Query: 2936 ICQPNG----QWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTG--KRSLLG 2989
C+ N QWD P C + CG P P N +G ++T S V Y C K
Sbjct: 2473 TCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQ 2532
Query: 2990 QSSRTCQLNGHWS--GSQPHCSGDATGTCGDPGTPGH-------GSRQESNFRTKSTVRY 3040
Q++ CQ +G WS G P C A + + H GS E + V
Sbjct: 2533 QATAVCQEDGLWSNKGKPPTCKPVACPSI-EAQLSEHVIWRLVSGSLNEYG----AQVLL 2587
Query: 3041 ACDTGYILHGSEERTCLANGSWT--GRQPECKAVQCGNPGTTANG-KVFRIDGTTFSSSV 3097
+C GY L G C ANG+W +P C+ + CG+ NG K+ + T + ++
Sbjct: 2588 SCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATA 2645
Query: 3098 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSY 3157
I++C GY L G VR+C ANG WSG+ C CG P NG GD + V Y
Sbjct: 2646 IFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVY 2705
Query: 3158 MCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISY 3217
C PG+ L G+ +R C + WSG P C +TC P ++G G+ F+ +++
Sbjct: 2706 QCNPGF--RLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNF 2763
Query: 3218 ICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREG-----KSFIYQSE 3272
C+ GY L + C NG WS +P C C DPG R G +SF Y
Sbjct: 2764 TCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMS 2823
Query: 3273 VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG 3332
+ + C F L+GSS C A+G W S P C+ SC +PGVP + F G
Sbjct: 2824 ILYHCKKGFYLLGSSALTCMANGLWDRSLPKCL---AISCGHPGVPANAVLTGEL-FTYG 2879
Query: 3333 SVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI---PHSCKQPETPAHANVVGMDLPS 3389
+VV + C+ L G+ TR C D WSG P C P C P TPAH + +G D +
Sbjct: 2880 AVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKT 2939
Query: 3390 HGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLS 3449
L ++C+ G L G E R C + +W+G P+CEA + +P GTP+ +
Sbjct: 2940 KS-LLRFSCEMGHQLRGSPE-RTCLLNGSWSGLQPVCEA---VSCGNP----GTPTNGMI 2990
Query: 3450 VPDD--VFAQNYI---WKG 3463
V D +F+ + I W+G
Sbjct: 2991 VSSDGILFSSSVIYACWEG 3009
Score = 414 bits (1065), Expect = e-115
Identities = 187/279 (67%), Positives = 227/279 (81%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG ++G NGTIESPGFP+GYPN ANCTW+II ERNRIQ+ F +FALEE++D LS+YDG
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 144
P N + RL+GF LP + ST S+ +L T+DFAVSA GFK YE L S +CGNPG
Sbjct: 92 QPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEI 151
Query: 145 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 204
KGVL+GTRF++GDKIRYSC+ GYIL+GH LTCI + N ASWDFP P CRAE ACGGT
Sbjct: 152 LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGT 211
Query: 205 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 264
+RG+S ISSP FP+EY NNADCTWTI+AEPGDTI+L+FTDFQ+EE YD+LEI G+E P+
Sbjct: 212 LRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPS 271
Query: 265 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
IWL+GMN+P P+IS+KNWLRLHF +DSNHR +GF+A +Q
Sbjct: 272 IWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
Score = 184 bits (467), Expect = 1e-45
Identities = 112/319 (35%), Positives = 159/319 (49%), Gaps = 45/319 (14%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGGTL+G + +I SP FP Y N A+CTW I+AE + I +VF F LEE YD+L + G
Sbjct: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI-SG 266
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE------------- 131
P+ + LTG +LP PV S+K+ L TSD GF ++
Sbjct: 267 TEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVK 323
Query: 132 -------------------ELQSSSCGNPGVPPKGVLYGTRFD-VGDKIRYSCVTGYILD 171
L S C +PG+P G G+ F VG +++SC Y+L
Sbjct: 324 MLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQ 383
Query: 172 GHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI 231
G +TC + A+W PICRA CG +RG SG+I+SP++P +Y +NA C W I
Sbjct: 384 GSKSITCQRVTETLAAWSDHRPICRAR-TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVI 442
Query: 232 -VAEPGDTISLIFTDFQMEEKYDYLEI-----EGSEPPTIW-LSGMNIPPPIISNKNWLR 284
+P I L F +F++E YD L + G ++ L+G ++P I+S N +
Sbjct: 443 TTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMW 502
Query: 285 LHFVTDSNHRYRGFSAPYQ 303
LH +D + GF A YQ
Sbjct: 503 LHLQSDDSIGSPGFKAVYQ 521
Score = 182 bits (461), Expect = 7e-45
Identities = 98/291 (33%), Positives = 145/291 (49%), Gaps = 8/291 (2%)
Query: 17 TASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEY 76
T + C G GTI SPG+P Y N NC W II E + IQI SFA E+ +
Sbjct: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
Query: 77 DYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSS 136
D L ++DG +G +P + ST + L SD +V+A GF + Y+ + +
Sbjct: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
+C P +P + G R+ V D + + C GY L G ++C+ +V W++P P+C
Sbjct: 1915 ACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVR--RWNYPSPLCI 1972
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 256
A CGGT+ G+I SP FP Y NN DCTW I G + F +F E +D+LE
Sbjct: 1973 A--TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
Query: 257 IEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
I+ + P SG ++P ++S + +HF +D + +GF YQ
Sbjct: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQ 2081
Score = 177 bits (448), Expect = 2e-43
Identities = 100/286 (34%), Positives = 152/286 (53%), Gaps = 13/286 (4%)
Query: 24 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLY 82
TCG L+G +G I SP +P Y + A+C WVI + ++ I++ F+ F LE YD L++
Sbjct: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVG 470
Query: 83 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
D + LTG +P + S + L L SD ++ + GFK Y+E++ CG+
Sbjct: 471 DAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD 530
Query: 141 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
PG+P G G+ F GD + + C + L G +TC N+ W P C +
Sbjct: 531 PGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN----QWSGNKPSC--VFS 584
Query: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--E 258
C SSGII SP++P EY NN +C W I++EPG I LIF DF +E ++D+L + +
Sbjct: 585 CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDD 644
Query: 259 GSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
G T+ SG +P + S+ + +RL F +D + RGF+ Y
Sbjct: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
Score = 169 bits (428), Expect = 5e-41
Identities = 98/287 (34%), Positives = 144/287 (50%), Gaps = 8/287 (2%)
Query: 22 IYTCGGTLKGL-NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 80
I CGG + +G I SPG+P Y N +CTW+I A+ I + F F E +D L
Sbjct: 1275 IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILK 1334
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
++DG +G LP + ST + +L+ SDF +S GF + + +++C +
Sbjct: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCND 1394
Query: 141 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
PG+P G YG + GD + + C GY L G ++TC+ + N W P C A A
Sbjct: 1395 PGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLN-NRFFWQPDPPTCIA--A 1451
Query: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--- 257
CGG + G +G+I SP++P Y +C W + P I+LIF F ME YD+L I
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
Query: 258 EGSEPPTIW-LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
E S P I G P I S+ N L L F +D++ GF+ ++
Sbjct: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
Score = 167 bits (424), Expect = 1e-40
Identities = 91/287 (31%), Positives = 140/287 (48%), Gaps = 8/287 (2%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
+++C +G I SP +P Y N NC W+II+E +RI ++F F +E ++D+L++
Sbjct: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
Query: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
D +G +P + S+ + L SD + + GF + Y + C +P
Sbjct: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDP 701
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
G+P G +G RF +G + + C G++ G +TCI N W VP C A
Sbjct: 702 GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVV-WSSTVPRCEA--P 758
Query: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE-- 258
CGG + SSG+I P +P Y ++ C W I A+PG +I + F FQ E YD LE+
Sbjct: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
Query: 259 --GSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
S P G P +IS N++ L F TD++ GF Y+
Sbjct: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE 865
Score = 166 bits (421), Expect = 3e-40
Identities = 101/288 (35%), Positives = 143/288 (49%), Gaps = 18/288 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD- 83
CGG ++G +GT+ SPGFP YPN NCTW I +Q++F +F LE +DYL + +
Sbjct: 931 CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITED 990
Query: 84 -GHPHPTNFRTRLTGFHLPPPVTS---TKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
P RLTG LP + + LR SDF++S GF + + E C
Sbjct: 991 GSFSEPV---ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCD 1047
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
+PGVP G F VGD + +SC GY L+G +LTC+ W P+P C AE
Sbjct: 1048 DPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRV--WSAPLPRCVAE- 1104
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI-- 257
CG +++G+ G + SP+FP+ Y NN +C + I E G I L FQ+ E D L++
Sbjct: 1105 -CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-DTLKVYD 1162
Query: 258 ---EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
S P + + + S N L L F T+ + +GF Y
Sbjct: 1163 GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
Score = 159 bits (403), Expect = 4e-38
Identities = 97/286 (33%), Positives = 143/286 (50%), Gaps = 14/286 (4%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L +G I PG+P Y + +C W+I A+ + I+I F F E YD L + DG
Sbjct: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEE--LQSSSCGNPG 142
+ G P + ST + L T+D + S+ GF ++YE L+S SC +PG
Sbjct: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 878
Query: 143 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
+P G +G F + + +SC GY L L C N W+ +P C A CG
Sbjct: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNH----QWNHALPSCDA--LCG 932
Query: 203 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--EGS 260
G ++G SG + SP FP+ Y N+ +CTWTI G + +IF F +E +DYL I +GS
Sbjct: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGS 992
Query: 261 -EPPTIWLSGMNIPPPI---ISNKNWLRLHFVTDSNHRYRGFSAPY 302
P L+G +P I + +L F++D + Y GF+ +
Sbjct: 993 FSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF 1038
Score = 159 bits (403), Expect = 4e-38
Identities = 93/273 (34%), Positives = 134/273 (49%), Gaps = 8/273 (2%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
I TCGGTL L G I SPGFP YPN +CTW I I F +F+ E +D+L +
Sbjct: 1972 IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEI 2031
Query: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
+G H + + +G LP + ST + SD + + GFK+ Y+ + +C +P
Sbjct: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
G + + + VG + + C GYIL GHP LTC + +N +W++P P C A C
Sbjct: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC-QHGIN-RNWNYPFPRCDA--PC 2147
Query: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI---- 257
G + +G I SP FP+EY DC W I PG + + FT Q E DY+ +
Sbjct: 2148 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGP 2207
Query: 258 EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTD 290
+ + P SG S+ N + L F +D
Sbjct: 2208 DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
Score = 138 bits (348), Expect = 9e-32
Identities = 105/296 (35%), Positives = 138/296 (46%), Gaps = 20/296 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CG ++KG GT+ SP FP Y N C + I E I + +SF L E D L +YDG
Sbjct: 1105 CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-DTLKVYDG 1163
Query: 85 -----HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
P T + L G L ST + L ++ + + GF++ Y C
Sbjct: 1164 KDSSSRPLGTFTKNELLGLIL----NSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
Query: 140 NPGVPPKGVLYGTRFDVGDKI-RYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
+PG+P G D + YSC GY + G LTC+ S + WD P+P C AE
Sbjct: 1220 DPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL--SGDRRVWDKPLPSCIAE 1277
Query: 199 DACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 257
CGG + +SG I SP +P Y NN CTW I A+PG TISL F F E +D L++
Sbjct: 1278 --CGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKV 1335
Query: 258 -EGSEPPTIWL---SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
+G I L SG +P I S N L L F +D GFS + S T
Sbjct: 1336 WDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Score = 137 bits (345), Expect = 2e-31
Identities = 86/289 (29%), Positives = 129/289 (44%), Gaps = 12/289 (4%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
I CGG L G G I SP +P YP G C W + I ++F+SF +E YD+L +
Sbjct: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
Query: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Y+G + G P + S+ + L SD +V GF + ++E +C +P
Sbjct: 1509 YEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDP 1568
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
G G GT F +G I Y C +GY + +TC+ + SWD +P C A C
Sbjct: 1569 GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA--PC 1626
Query: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQ-----MEEKYDYLE 256
GG GS G++ SP++P+ Y C ++I + F FQ + E +D
Sbjct: 1627 GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTH 1686
Query: 257 IEGSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
+ ++ SG +P ++ N + L F S RGF YQ
Sbjct: 1687 AQARLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQ 1732
Score = 132 bits (333), Expect = 5e-30
Identities = 98/318 (30%), Positives = 143/318 (44%), Gaps = 25/318 (7%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CG + NGTI SPGFP YP +C W+I + + I F E DY++++DG
Sbjct: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
Query: 85 HPHPTNFRTRLTGFH----LPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
P +L F L +ST V L+ SDF+ F + + Q C
Sbjct: 2207 ---PDQNSPQLGVFSGNTALETAYSSTNQVL-LKFHSDFSNGGF-FVLNFHAFQLKKCQP 2261
Query: 141 PGVPPKGVLY--GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
P P+ + F++GD ++Y C GY L G LTC +S ++ +P C A+
Sbjct: 2262 PPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS--QLQFEGSLPTCEAQ 2319
Query: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
GSSG+I SP +P Y N+ C+W+I EP I++ FQ E+++D LE+
Sbjct: 2320 CPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVF 2379
Query: 258 ---EGSEPPTIWLSGMNIPPP-IISNKNWLRLHFVTDSNHRYRGF----SAPYQGSSTLT 309
G P + LSG + S N L L + TD +GF +APY +LT
Sbjct: 2380 DGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPY---CSLT 2436
Query: 310 HTTSTGELEEHNRTTTGA 327
H G + G+
Sbjct: 2437 HPLKNGGILNRTAGAVGS 2454
Score = 125 bits (314), Expect = 8e-28
Identities = 85/289 (29%), Positives = 124/289 (42%), Gaps = 15/289 (5%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEY--DYLSLY 82
CGG G G + SP +P+ Y G C + I + +VF FA + D L+
Sbjct: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEF---VVFGQFAYFQTALNDLAELF 1682
Query: 83 DGHPHPTNFRTRLTGFHLPPPVT-STKSVFSLRLTSDFAVSAHGFKVYYEELQSSS---C 138
DG + L+G H + +T + LR ++ SA GF Y+ + +S C
Sbjct: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQC 1742
Query: 139 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
+ P G G+ F G +R+ C GY+L G L C + A W+ +P C
Sbjct: 1743 SSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVV- 1801
Query: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
C G G I SP +P Y NN +C W I+ G I + F E+ +D LEI
Sbjct: 1802 -PCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
Query: 258 ---EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
+ + P SG +P + S N L LHF +D + GF Y+
Sbjct: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYK 1909
Score = 93.6 bits (231), Expect = 3e-18
Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 31 GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTN 90
G +G I SPG+P Y N C+W I E I I +F E+++D L ++DG +
Sbjct: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSP 2387
Query: 91 FRTRLTGFHLPPP-VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVL 149
L+G H TS + LR ++D A S GFK+ Y S +P + G+L
Sbjct: 2388 LLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA-PYCSLTHP-LKNGGIL 2445
Query: 150 YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
T VG K+ Y C GY + GH TC N + WD P+C+A +CG
Sbjct: 2446 NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV-SCG 2497
Score = 53.1 bits (126), Expect = 5e-06
Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
+CG+PG P G G+ F++ D + ++C TGY+L G + C +N W P+P CR
Sbjct: 2738 TCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSN----GQWSSPLPTCR 2793
Score = 52.4 bits (124), Expect = 8e-06
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
CG+PG P G G F +R+SC G+ L G P+ TC+ N SW P+C A
Sbjct: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN----GSWSGLQPVCEA 2976
Query: 198 EDACGGTMRGSSGIISS 214
+CG ++G+I S
Sbjct: 2977 V-SCGNPGTPTNGMIVS 2992
Score = 42.0 bits (97), Expect = 0.011
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
SCG+PG G+ +GT F + Y C GY+++ T W+ P+C+
Sbjct: 3037 SCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSAT--IRCTKDGRWNPSKPVCK 3094
Query: 197 A 197
A
Sbjct: 3095 A 3095
Score = 40.4 bits (93), Expect = 0.033
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 137 SCGNPGVPPKGVLYGTR-----FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 191
+C +PG + +G + F+ G I Y C G+ L G LTC+AN + WD
Sbjct: 2796 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGL----WDRS 2851
Query: 192 VPICRAEDACG 202
+P C A +CG
Sbjct: 2852 LPKCLA-ISCG 2861
Score = 40.0 bits (92), Expect = 0.043
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
SCG+PGVP VL G F G + YSC L G+ C +S W +P C
Sbjct: 2859 SCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDS----HWSGALPHCT 2914
Query: 197 AEDA--CG 202
+ CG
Sbjct: 2915 GNNPGFCG 2922
Score = 37.7 bits (86), Expect = 0.21
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
CG+PG+P +G L G F ++ + C + +IL G + C A+ +W P C
Sbjct: 3156 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQAD----GTWSGIQPTC 3209
Score = 37.0 bits (84), Expect = 0.36
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 136 SSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIAN 181
++C +PG P G+ +R ++VG + + C GY + G TC+AN
Sbjct: 3215 NTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLAN 3261
Score = 36.2 bits (82), Expect = 0.61
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
SCG+ PP G GT G ++C TGY L G C+AN + W C
Sbjct: 2622 SCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGL----WSGSETRCL 2677
Query: 197 AEDACGGTMRGSSGIISSPSF 217
A CG +G IS F
Sbjct: 2678 A-GHCGSPDPIVNGHISGDGF 2697
Score = 35.8 bits (81), Expect = 0.80
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
C P G + G+ F G I YSC+ GY L L+C V W +P C
Sbjct: 3098 CPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGV----WKGEIPQC-L 3152
Query: 198 EDACGGTMRGSSGIISSPSF 217
CG + G +S SF
Sbjct: 3153 PVFCGDPGIPAEGRLSGKSF 3172
Score = 34.3 bits (77), Expect = 2.3
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 6/79 (7%)
Query: 134 QSSSCGNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 192
++ SCGNPG P G++ + + Y+C GY G C AN +W
Sbjct: 2975 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN----GTWTGTA 3030
Query: 193 PICRAEDACGGTMRGSSGI 211
P C +CG ++GI
Sbjct: 3031 PDCTI-ISCGDPGTLANGI 3048
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 3696 bits (9584), Expect = 0.0
Identities = 1702/2976 (57%), Positives = 2168/2976 (72%), Gaps = 82/2976 (2%)
Query: 406 HRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 465
++VKK I+ KSRG KL P KDNS K S+L + G+ N+CPDPG PE GKR+GSDF LG
Sbjct: 303 YQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLG 362
Query: 466 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 525
S+VQF+C+E Y LQG+K ITC +++++FAAWSDHRPVC+ + C ++L+GPSG TSPNFP
Sbjct: 363 SSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFP 422
Query: 526 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 585
QYD+NA CVW+ITA+N +KVI++ FEEFDLE GYDTLT+GDGG+ GD +TVL +LTG+
Sbjct: 423 IQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTS 482
Query: 586 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 645
VPDLIVS + QMWL QTD S S+GFK +Y+EIE+ SCGDPG P YG REG F + D
Sbjct: 483 VPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDT 542
Query: 646 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 705
L+FECQ FEL+G+K+I CQ+NNQWSA P C+F C NFT+P G VLSP+YPE YGN+L
Sbjct: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
Query: 706 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 765
+C+W I++ P SRIHL+FND D+E QFDFL +KDG + E+P+LGTF+G ++PS +TS+ H
Sbjct: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
Query: 766 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 825
+ RLEFQ DHS RGFNIT+ TF HNECPDPG+P+N +RFGD+ QLGSSIS +C+EGF+
Sbjct: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
Query: 826 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 885
TQG+ETITC+L +G V+W+ + +C APCGGH ++PSG ILSPGWPG+YKD+L+C WVI
Sbjct: 723 GTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVI 782
Query: 886 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 945
EA+PG+ IKITF+RF+TE+NYD LEV DG +PL+G Y+GTQVPQFL S+SN++YLLF
Sbjct: 783 EAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLF 842
Query: 946 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 1005
+TD S S+ GF++ YE++T+ + CLDPGIPV+G+R+G+DF +G+ V+FSCDSGY LS
Sbjct: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDG 902
Query: 1006 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
EPL CE N WS LP+C+ALCGG ++G SGTILSPG+P+FYPN+LNCTW ++ +HGKGV
Sbjct: 903 EPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGV 962
Query: 1066 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1125
F FHTFHLE HDYLLITENGSFTQPL +LTGS LP I+AGLYGNF AQ+RFISDFS+
Sbjct: 963 FFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSM 1022
Query: 1126 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1185
SYEGFNITFSEY+LEPCE+P +P Y R G FG+GDTLTFSC GYRLEGT+ I CLGG
Sbjct: 1023 SYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGG 1082
Query: 1186 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1245
RR+WS+PLPRCVAECG S T +G LLSPN+P+NY NNHECIYSIQ Q GKGI + AR
Sbjct: 1083 RRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARA 1142
Query: 1246 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1305
F L++GDVLK+YDG + + LLG F+ + M G+TL+STS+ LWL+F +D E T +GF+L
Sbjct: 1143 FELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELH 1202
Query: 1306 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
++SFEL CEDPG P+FGYK+ D+GHFAGS++ + C+PGY+L GS L C++GERR WD
Sbjct: 1203 FSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDR 1262
Query: 1366 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1425
PLP+C+AECGG +GE SG++LSPGYP PY++NL C+W IE + G + L FL FDTE
Sbjct: 1263 PLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV 1322
Query: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485
HD+LR+WDGP E+ +LLKE+SG +P+ +HST N V +QF TDF+ SK GFAIQFS S A
Sbjct: 1323 HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTA 1382
Query: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
T+C DPG+P NG+R+GD E GD+ VFQCDPGY LQG I+C+++ENR+FWQPSPP CI
Sbjct: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
APCGG+LTG SG ILSPN+P PYP ++CDW +TV+ DYVI+L F F++EP YDFL+IY
Sbjct: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
Query: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1665
DG DS SPLIGSF S+LP RIESSSN++ LAFRSD SVS GF ++Y RESCFDPG
Sbjct: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPG 1562
Query: 1666 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1725
+I NGTR+G D KLGS+VTYYC GY ++G STL+CI+G DG+P WN P C APCG +
Sbjct: 1563 SIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQ 1622
Query: 1726 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1785
GS+G VLSPNYP+NY+ G C+Y + VPK++VVFGQF FF T+L+DVVEV+DG +Q S
Sbjct: 1623 YVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHS 1682
Query: 1786 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1845
LLSSLSGSH+GESLPL++ NQ+ I+F++ G A+GFHFVYQAVPRTS+TQCSSVPEPR
Sbjct: 1683 RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPR 1742
Query: 1846 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1905
+G+R+G++F+VG+ V F+CN GY L GS I C VP +LAQWN S PTC+VPCGG LT+
Sbjct: 1743 YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
Query: 1906 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1965
R+GTILSPG+PEPY N+LNCVWKI VPEGAGIQ+QVVSF TE NWDSL+ +DG DN
Sbjct: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
Query: 1966 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 2025
LGS+SGTT+P LLNSTSN LYL+F SDISVSAAGFHLEY +GL SCPEP PS+G+K G
Sbjct: 1863 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG 1922
Query: 2026 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2085
+RY+V DVVSFQC+ GY+LQGH+HI+CMPG VRRWNYP P+C+AQCGG + + GVILSP
Sbjct: 1923 ERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSP 1982
Query: 2086 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2145
GFPGNYPS++DC+W I LP+GFG H+QF+NFSTE HDY+E+R+G ETS ++GR SG +
Sbjct: 1983 GFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSE 2042
Query: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ---------------------------- 2177
+PSSL ST+HET++YFHSD+SQN+ GF + YQ
Sbjct: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPP 2102
Query: 2178 --------------AYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALT 2223
AY+LQ CPDP PF NG V G + VGQ+++FEC PGY L G+ LT
Sbjct: 2103 VAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLT 2162
Query: 2224 CLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYI 2283
C HG +RNW+HPLP+CE CGGNIT+ NGT+YSPG+P Y + QDC WL+ VP G+G+ +
Sbjct: 2163 CQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRL 2222
Query: 2284 NFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFF 2343
N ++LQTEP DFIT+WDGP Q +P++G F+ + A ++V S+SNQ+L+KFH D T G F
Sbjct: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
Query: 2344 VLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERL 2403
+++ AY L C PP +PNAE++TE++EF IGDI+RY+CLPGFTLVGN ILTC+LG L
Sbjct: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYL 2342
Query: 2404 QMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF 2463
Q +G PP+C+V CP NEL DSTGVILS YP SYP Q C+W + VE YNI++ VE+F
Sbjct: 2343 QFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYF 2402
Query: 2464 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIR 2523
+EK++D +++DGP+ QSP+L +LSG+YS+ +TS+ + V+L+WS+DH N+KGF+IR
Sbjct: 2403 LSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIR 2462
Query: 2524 YIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAP 2583
Y A YCS P +P HG+I+ QT Q + + C+ G+RLVG S A+C + GYH W
Sbjct: 2463 YSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
Query: 2584 VPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2643
+P CQA+SCG+P+AP NG + +Y VGT+ Y C++GY L + TA C G WSN
Sbjct: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNR 2582
Query: 2644 NKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNG 2703
N P+CV VTCP ++S +EHGRWR++ + Y+++ +++ CDPGY+ G I C NG
Sbjct: 2583 NVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANG 2642
Query: 2704 TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG 2763
WS + P C+IISCGELP PPNG++IGT + YG+TAIF+C+ G+ LVGS VREC+++G
Sbjct: 2643 KWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2702
Query: 2764 LWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2823
LWS SE RCLAGHCG PE IVNG + GENY YR +VVYQCN GFRLIG SVRICQQDH+W
Sbjct: 2703 LWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHW 2762
Query: 2824 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2883
SG+ P CV VSCGHPGSP + + SG+ + VV +SC + G + C + W+
Sbjct: 2763 SGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTG 2822
Query: 2884 PPPMC---KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2940
P C V C DPGIPA+ R +F GTV+ + C G+ L GSS CQ N
Sbjct: 2823 SLPHCSGTSVGVCGDPGIPAHGIRLG----DSFDPGTVMRFSCEAGHVLRGSSERTCQAN 2878
Query: 2941 GQWDKPLPECIMIDCGHPGVPPNA-VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 2999
G W PEC +I CG+PG P NA V+ + F S++ Y C G SR C +NG
Sbjct: 2879 GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG 2938
Query: 3000 HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYIL--HGSEERTCL 3057
W+GS P C CGDPG P +G R ++FR TV Y C GY++ H +C
Sbjct: 2939 TWTGSDPEC---LVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCT 2995
Query: 3058 ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTA 3117
+ +W G +P CKA+ C P NGKV D + SSV Y+C+EGY LS P+V C
Sbjct: 2996 KDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD-FMWGSSVTYACLEGYQLSLPAVFTCEG 3054
Query: 3118 NGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTI 3177
NG+W+G LP C + CGDPG+P+ G R + +VS+ C P + L GS R C
Sbjct: 3055 NGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHP--PLVLVGSPRRFCQS 3112
Query: 3178 NGTWSGVMPTC---RAVTCPTP--PQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLT 3232
+GTWSG P+C TC P PQ + + G ++ + C GY L T
Sbjct: 3113 DGTWSGTQPSCIDPTLTTCADPGVPQFGI-QNNSQGYQVGSTVLFRCQKGYLLQGSTTRT 3171
Query: 3233 CVGNGTWSGEVPQCLPKFCGDPGIPAQGK-------REGKSFIYQSEVSFSCNFPFILVG 3285
C+ N TWSG P C+P C P P G + IY + FS + G
Sbjct: 3172 CLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFS-----LKGG 3226
Query: 3286 SSTRICQADGTWSGSSPHCIE------PTQTSCENP 3315
S R C+ADG+W+G P C+E P T+ E P
Sbjct: 3227 SEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPP 3262
Score = 2254 bits (5841), Expect = 0.0
Identities = 1256/3413 (36%), Positives = 1815/3413 (53%), Gaps = 249/3413 (7%)
Query: 443 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
S+ C +PG NG + GS F+LG V++SC+ + L+G +TC +E A W P
Sbjct: 136 SHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
Query: 503 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
C+ CG L+G SG +SP+FP +Y +NA C W I A I + F +F LE GYD
Sbjct: 196 CRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILA-ELGDTIALVFIDFQLEDGYD 254
Query: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 618
L + G + L TG+ +P ++S + + LH +D + GF Y K+
Sbjct: 255 FLEV-----TGTEGSSLW-FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
Query: 619 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDVLRFE 649
IE +S C DPG P G R G F ++F
Sbjct: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFT 368
Query: 650 CQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNN 704
C G++L G K I C + + WS + P+C C ++ P G + SP++P Y NN
Sbjct: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
Query: 705 LNCIWTIIS-DPGSRIHLSFNDFDLESQFDFLAVKDG--DSPESPILGTFTGAEVPSHLT 761
+C+W I + +P I L+F +FDLE +D L V DG D + +L TG VP +
Sbjct: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
Query: 762 SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICE 821
S +H + L FQ D S S GF +Y C DPGIP RR G F G ++ C+
Sbjct: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQ 548
Query: 822 EGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNC 881
F + G + ITC WS P C C +F++PSGV+LSP +P Y + L+C
Sbjct: 549 PAF-ELVGQKAITC---QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
Query: 882 EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI 941
W+I A P I + F E +D L + DG +P+LG+++G Q+P + SS +
Sbjct: 605 VWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVA 664
Query: 942 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYR 1001
L F TD+S GF I + + N C DPG+PV+G+R+G +GS++SF CD G+
Sbjct: 665 RLEFQTDHSTGKRGFNITFTTFRHN--ECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
Query: 1002 LSH-EEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTV 1057
+ E + C E + W+ + C+A CGG + PSGTILSPG+P FY ++L+C W +
Sbjct: 723 GTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVI 782
Query: 1058 DVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT-GSDLPP-TINAGLYGNFRA 1115
+ G ++ F F E ++D L + + +++ PL + G+ +P I+ Y
Sbjct: 783 EAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNY----L 838
Query: 1116 QLRFISDFSISYEGFNITFSEYNLEP--CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR 1173
L F +D S S GF + + L+ C DPGIP G R G +F +G +TFSC SGY
Sbjct: 839 YLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYT 898
Query: 1174 LEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQV 1233
L + C + WS LP C A CG + G +LSP +P Y NN C + I+
Sbjct: 899 LSDGEPLECEPNFQ--WSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIET 956
Query: 1234 QAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASM-----RGLTLSSTSNQLW 1288
GKG+ + TFHL G + T L TG+ + GL + T+
Sbjct: 957 SHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQ--- 1013
Query: 1289 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1348
+ F SD + EGF + ++ ++L CE+P +P + + Q G T+ + C PGY L
Sbjct: 1014 VRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ-FGVGDTLTFSCFPGYRLE 1072
Query: 1349 GSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVD 1408
G++ + C+ G RR W PLP C+AECG G + G +LSP +P Y+NN C++ I+
Sbjct: 1073 GTARITCLGGRRRLWSSPLPRCVAECGNSVTG-TQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
Query: 1409 PGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS-LIPEGIHSTLNIVTIQFDT 1467
PG + L+ AF+ D+L+V+DG + LL S S ++ ++ST + + + F T
Sbjct: 1132 PGKGIQLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
Query: 1468 DFYISKSGFAIQFSSSVATACRDPGVPMNGTR-NGDGREPGDTVVFQCDPGYELQGEERI 1526
D + GF + FSS C DPG P G + + +G G +V F CDPGY L+G E +
Sbjct: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
Query: 1527 TCIQVENRYFWQPSPPVCIAPCGGNLTGS-SGFILSPNFPHPYPHSRDCDWTITVNADYV 1585
C+ E R W P C+A CGG + G SG +LSP +P PY H+ +C WTI A
Sbjct: 1251 LCLSGERRT-WDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCT 1309
Query: 1586 ISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVS 1645
I L F+ F E +D L I+DGP + L+ LP+ + S+ N++ L F +D S
Sbjct: 1310 IGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTS 1369
Query: 1646 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGD 1705
GF +++ SC DPG NG+R G ++ G + + CD GY LQG + ++C+ +
Sbjct: 1370 KQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
Query: 1706 DGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV 1765
+ R W + P+C APCG TG G +LSPNYP+ Y G C + + V ++V+ F
Sbjct: 1430 N-RFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
Query: 1766 FFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFH 1824
F +D + +YDG S L+ S GS + SS N + + F S ++ GF
Sbjct: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIE-SSSNSLFLAFRSDASVSNAGFV 1547
Query: 1825 FVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNS 1884
Y PR S S+ G R+G++ +GSSV + C+ GY + G+ + C P+
Sbjct: 1548 IDYTENPRESCFDPGSIKN---GTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
Query: 1885 LAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF 1944
WN+ P C PCGG G +LSP YP+ Y + C++ +TVP+ + Q F
Sbjct: 1605 KPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFF 1664
Query: 1945 ATEHNWDSLDFYDGGDNNAPRLGSYSGT-TIPHLLNSTSNNLYLNFQSDISVSAAGFHLE 2003
T N D ++ +DG ++ L S SG+ T L +TSN + + F + A GFH
Sbjct: 1665 HTALN-DVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFV 1723
Query: 2004 YTAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMP--GPVR 2058
Y A+ S C P G ++G + VG +V F+C+ GY+LQG I C+P G +
Sbjct: 1724 YQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALA 1783
Query: 2059 RWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2118
+WN P C+ CGG +++ G ILSPGFP Y +SL+C W I +P G G+ +Q V+F T
Sbjct: 1784 QWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
Query: 2119 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
E D LEV G+ T T++G SG +P+ L ST+++ L+F+SD S + GFH+ Y+
Sbjct: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
Query: 2179 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
L SCP+P NG G + V +SF+C PGY L G++ ++C+ G R WN+P P
Sbjct: 1904 VGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPL 1963
Query: 2239 CEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFIT 2298
C A CGG + M G I SPG+P YP+ DC W + +P G G +I F TEP +D+I
Sbjct: 1964 CIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIE 2023
Query: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFV----LSY----- 2347
+ +GP + S +G+FSG+ S+ STS++ + FHSD + + GF + L+Y
Sbjct: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQIS 2083
Query: 2348 --------------------------------HAYQLRVCQPPPPVPNAEILTEDDEFEI 2375
AY+L+ C P P N + + +
Sbjct: 2084 SFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANG--IVRGAGYNV 2141
Query: 2376 GDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYP 2435
G + ++CLPG+ L G+ +LTC+ G D P C+V C N S G + SPG+P
Sbjct: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNIT--SSNGTVYSPGFP 2199
Query: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSA 2495
Y + Q C W I+V G+ + + + QTE D + ++DGP +P L + +
Sbjct: 2200 SPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKK 2259
Query: 2496 FNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESPPHGYIISQTGG-QLNSV 2551
+ S+ ++V L++ D F I + A+ C P P+ ++++ + +
Sbjct: 2260 -TVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDI 2317
Query: 2552 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG-GILTT---- 2606
VR+ C GF LVG C+ +Y ++ P P C+ + C + T+ G++ +
Sbjct: 2318 VRYRCLPGFTLVGNEILTCKLGTY--LQFEGPPPICE-VHCPTNELLTDSTGVILSQSYP 2374
Query: 2607 -----------------DYLVGTRVTYFCNDGY------------------RLSSKELTT 2631
DY + V YF ++ LS
Sbjct: 2375 GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAP 2434
Query: 2632 AVCQSDGT-----WSNHN-----------KTPRCVVVTCPSINSFILEHGRWRIVNGSHY 2675
+ S WS+ + P C + P ++ FIL + H
Sbjct: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAP-LHGFILGQTSTQPGGSIH- 2492
Query: 2676 EYKTKVVFSCDPGYHGLGPASIECL--PNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2733
F C+ GY +G + C P G W P CQ +SCG P NG G
Sbjct: 2493 -------FGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGK 2545
Query: 2734 QTSYGSTAIFTCDLGFMLVGSA--VRECLSSGLWSESET--RCLAGHCGIPEL----IVN 2785
+ + G+ A+++C G+ L A ECL +GLWS +C+ C P++ + +
Sbjct: 2546 EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTC--PDVSSISVEH 2603
Query: 2786 GQ---VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWS--GQLPSCVPVSCGHPGS 2840
G+ + Y ++ ++ C+PG+ G V CQ + WS P+C +SCG
Sbjct: 2604 GRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPI 2663
Query: 2841 PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2900
P G G + FSCN GY + G +C AN WS C +C P
Sbjct: 2664 PPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIV 2723
Query: 2901 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGV 2960
N I N++Y V Y CN G+ L G SV ICQ + W P C+++ CGHPG
Sbjct: 2724 NGH----INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGS 2779
Query: 2961 PPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG 3020
PP++ +SG+ YT G+ V YSC GKR+L+G S+R C L+GHW+GS PHCSG + G CGDPG
Sbjct: 2780 PPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPG 2839
Query: 3021 TPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTT 3080
P HG R +F + +R++C+ G++L GS ERTC ANGSW+G QPEC + CGNPGT
Sbjct: 2840 IPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTP 2899
Query: 3081 ANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPA 3140
+N +V DG FSSS++Y C EGY +G R C+ NGTW+G+ P C +I+CGDPGIPA
Sbjct: 2900 SNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPA 2959
Query: 3141 NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS 3200
NGLR G+D+ + V+Y C PGY ME + + +CT + TW+G P C+A+ C PP I
Sbjct: 2960 NGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIP 3019
Query: 3201 NGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG 3260
NG++ G++F WG S++Y C GY+LS PAV TC GNG+W+GE+PQC P FCGDPG+P++G
Sbjct: 3020 NGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRG 3079
Query: 3261 KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3320
+RE + F Y+S VSFSC+ P +LVGS R CQ+DGTWSG+ P CI+PT T+C +PGVP+
Sbjct: 3080 RREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQF 3139
Query: 3321 GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHA 3380
G QNN+ G+QVGS V F C+KG+LLQGSTTRTCLP+LTWSG P+C+PH C+QPETP HA
Sbjct: 3140 GIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHA 3199
Query: 3381 NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC----EAGSKILVKD 3436
NV +DLPS GYTLIY+CQ GF L GG+EHR C++D +WTGK PIC +G I
Sbjct: 3200 NVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI---- 3255
Query: 3437 PRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT-LSNS 3495
A P + +P DVFA+N +WKG+Y ++G+KQP L VT F + +VNAT + +S
Sbjct: 3256 -NTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHS 3314
Query: 3496 NMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGF 3555
+EL L+G YK ++ L+L++Y I P + K K+++WA+DG VS+E GAT+++QG
Sbjct: 3315 GVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGS 3374
Query: 3556 IQGKDYGQFGLQRLGLNMSEGSNSSNQPH-GTNSSSVAIAILVPFFALIFAGFGFYLYKQ 3614
++G+ +GQFG QRL L + E S H +NSSSVA AILVPF ALI AGF YLYK
Sbjct: 3375 VKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKH 3434
Query: 3615 RTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3667
R PK + G + HEN N +A FENPMYD N + + A + ++TVCT V
Sbjct: 3435 RRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
Score = 1551 bits (4017), Expect = 0.0
Identities = 1023/3139 (32%), Positives = 1507/3139 (48%), Gaps = 289/3139 (9%)
Query: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 558
H P + C L GP+GT SP FP+ Y + A C W ITA ++ IQ+ F+ F LE
Sbjct: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
Query: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
+D L++ DG P + LTG +P IVS ++ + L L +D +V + GF Y+
Sbjct: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
Query: 619 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANI 674
+ +CG+PG GI++G F+ D +R+ C GF L G + C ++ W +
Sbjct: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
Query: 675 PICIFP--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQF 732
P C C G + SP +P Y NN +C WTI+++ G I L F DF LE +
Sbjct: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
Query: 733 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN----- 787
DFL V + FTGA +P+ + S+ + LRL F +D + RGF+ Y
Sbjct: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
Query: 788 ---------------------------TFGHNECPDPGIPINARRFGDNFQLGSSISVIC 820
+ GHN CPDPGIP +R G +F+LGSS+ C
Sbjct: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
Query: 821 EEGFIKTQGTETITCI-LMDGKVMWSGLIPKCGAP-CGGHFSAPSGVILSPGWPGYYKDS 878
EG+ QG++ ITC+ + D WS P C A C H PSG+I SP +P Y ++
Sbjct: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
Query: 879 LNCEWVIEA-EPGHSIKITFERFQTELNYDVLEVHDG--PNLLSPLLGSYNGTQVPQFLF 935
+C W+I A P IK+ FE F E YD L V DG +L GT VP +
Sbjct: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
Query: 936 SSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFS 995
S+++ ++LLF TD S S+ GFK YE + SC DPGIP +GRR G F G T+ F
Sbjct: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQG--SCGDPGIPAYGRREGSRFHHGDTLKFE 546
Query: 996 CDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTW 1055
C + L ++ + C+KN+ WS P C C + PSG +LSP YPE Y N L+C W
Sbjct: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
Query: 1056 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFR 1114
+ + F+ +E D+L+I + + P L +G+ LP +I +
Sbjct: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS---GHV 663
Query: 1115 AQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR- 1173
A+L F +D S GFNITF+ + C DPG+P G R G + +G +++F C G+
Sbjct: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
Query: 1174 LEGTSEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQ 1232
+G+ I C L G VW++ + RC A CG T+ G +LSP +P Y++ C + I+
Sbjct: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
Query: 1233 VQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEF 1291
Q G I I+ F D L++ DG+ + L+G + G + L STSN L+L F
Sbjct: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQF-LISTSNYLYLLF 842
Query: 1292 NSDTEGTDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1349
++D +D GFQL Y + L HC DPGIP G + + + G+ + + C+ GYTL
Sbjct: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGND-FYVGALVTFSCDSGYTLSD 901
Query: 1350 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1409
L+C + W LPSC A CGG +G SSG ILSPG+P Y NNL C W+IE
Sbjct: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQG-SSGTILSPGFPDFYPNNLNCTWIIETSH 958
Query: 1410 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFD 1466
G V F F E+ HD L + + L ++++GS +P I + L ++F
Sbjct: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFI 1017
Query: 1467 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERI 1526
+DF +S GF I FS C +P VP R G GDT+ F C PGY L+G RI
Sbjct: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
Query: 1527 TCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI 1586
TC+ R W P C+A CG ++TG+ G +LSPNFP Y ++ +C ++I I
Sbjct: 1078 TCLGGRRR-LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
Query: 1587 SLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVS 1645
L +F + D L +YDG ++++ L+G F S++ + S+S+++ L F +D +
Sbjct: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
Query: 1646 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMD-YKLGSTVTYYCDAGYVLQGYSTLTCIMG 1704
GF L + + C DPG G ++ + + GS+V++ CD GY L+G L C+ G
Sbjct: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
Query: 1705 DDGRPGWNRALPSCHAPCGSRSTGS-EGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1763
+ R W+R LP+C A CG G G VLSP YP Y NC+++I +
Sbjct: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
Query: 1764 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1822
F+ F T +HDV+ ++DGP + LL LSG + L S+ N + ++F++ + +G
Sbjct: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
Query: 1823 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1882
F + +++T C+ P+ G R G+ + G S +F C+PGY L GS I C +
Sbjct: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
Query: 1883 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1942
N W S PTCI PCGG LT G ILSP YPEPY C WK+TV I +
Sbjct: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
Query: 1943 SFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHL 2002
F E +D L YDG D+ +P +GS+ G+ +P + S+SN+L+L F+SD SVS AGF +
Sbjct: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
Query: 2003 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--W 2060
+YT +SC +P + +G ++G +G V++ C GY ++G S ++C+ GP + W
Sbjct: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
Query: 2061 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2120
N P P+C A CGG GV+LSP +P NY S C + + +P + V QF F T
Sbjct: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHT-A 1667
Query: 2121 IHDYLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY 2179
++D +EV G S+ S ++ LSG SL +T+++ + F + +GFH VYQA
Sbjct: 1668 LNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
Query: 2180 ------QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH--GVSRN 2231
Q S P+PR G +G+DF+VG + FEC GY L G+ + CL G
Sbjct: 1728 PRTSATQCSSVPEPR---YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
Query: 2232 WNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTE 2291
WN P C CGGN+T GTI SPG+P+ Y N +C W + VP G GI I TE
Sbjct: 1785 WNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTE 1844
Query: 2292 PIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAY 2350
+D + V+DG D +G FSG T + STSNQ+ + F+SD + S F L Y
Sbjct: 1845 QNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
Query: 2351 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2410
L C P P VP+ + T + + + D++ +QC PG+ L G+A ++C G + + PP
Sbjct: 1905 GLSSC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
Query: 2411 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2470
+C C ++ GVILSPG+P +YP+ C+W I++ G+ + F TE D
Sbjct: 1963 LCIAQCGGTVEEME--GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHD 2020
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
+++ +GP S ++ SG + ++ S HE + + +DH N+ GF++ Y S
Sbjct: 2021 YIEIRNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
Query: 2531 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2590
Q++S + RGF L + WD P C+A
Sbjct: 2080 ---------------HQISSFL-----RGFDLSELERTNSTPPVAASYVWDLD-PGCEAY 2118
Query: 2591 ---SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2647
C P+ NG + Y VG VT+ C GY+L+ + T ++ W + P
Sbjct: 2119 ELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLP 2176
Query: 2648 RCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSW 2707
+C V +I S NG+ Y PG+ +S +C+ W
Sbjct: 2177 KCEVPCGGNITS----------SNGTVY----------SPGFPSPYSSSQDCV----WLI 2212
Query: 2708 RNERPYCQIISCGELPTPPNGNKI----GTQTSYGSTAIFTCDLGFMLVGSAV------- 2756
+ ++ L T P+G+ I G Q + +FT + V S+
Sbjct: 2213 TVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKF 2272
Query: 2757 -RECLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSS 2813
R+ + G+++ + + C P ++ N +V+ EN + D V Y+C PGF L+G+
Sbjct: 2273 HRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNE 2332
Query: 2814 VRICQQDH--NWSGQLPSC---------------VPVSCGHPGS---------------- 2840
+ C+ + G P C V +S +PGS
Sbjct: 2333 ILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPD 2392
Query: 2841 -----------------------------PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT 2871
P+ SGN ++ +VT S N YL
Sbjct: 2393 YNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGN-YSAPLIVTSSSNSVYLRWSSD 2451
Query: 2872 KAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG 2931
A + + + P C + G G + + CN GY L G
Sbjct: 2452 HAYNRKGFKIRYSAPYCSLPRAPLHGFILGQTSTQP--------GGSIHFGCNAGYRLVG 2503
Query: 2932 SSVLICQPNGQ----WDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSL 2987
S+ IC + Q W + +P C + CG P P N ++ G++YT G+ YSC+ L
Sbjct: 2504 HSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHL 2563
Query: 2988 LGQSSRT--CQLNGHWSGSQ--PHCSGDATGTCGDPGTPG--HGSRQ---ESNFRTKSTV 3038
+ T C G WS P C TC D + HG + E+ ++ ++ +
Sbjct: 2564 QAGAEATAECLDTGLWSNRNVPPQC---VPVTCPDVSSISVEHGRWRLIFETQYQFQAQL 2620
Query: 3039 RYACDTGYILHGSEERTCLANGSWT--GRQPECKAVQCGNPGTTANGKVFRIDG-TTFSS 3095
CD GY G C ANG W+ P C+ + CG NG RI + + +
Sbjct: 2621 MLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGA 2678
Query: 3096 SVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNV 3155
+ I+SC GY L G VR+C ANG WSG+ C CG P NG G++Y +V
Sbjct: 2679 TAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSV 2738
Query: 3156 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3215
Y C G+ L G +R C + WSG P C V+C P + ++ G ++ G +
Sbjct: 2739 VYQCNAGF--RLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVV 2796
Query: 3216 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPK---FCGDPGIPAQGKREGKSFIYQSE 3272
Y C L + C +G W+G +P C CGDPGIPA G R G SF +
Sbjct: 2797 RYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTV 2856
Query: 3273 VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG 3332
+ FSC +L GSS R CQA+G+WSGS P C SC NPG P + + G
Sbjct: 2857 MRFSCEAGHVLRGSSERTCQANGSWSGSQPEC---GVISCGNPGTPSNARVVFSDGLVFS 2913
Query: 3333 SVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGY 3392
S + + C++G+ G +R C + TW+G PEC+ +C P PA+ +G D +
Sbjct: 2914 SSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDF-RYNK 2972
Query: 3393 TLIYTCQPGFFLAGGTEHRV----CRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKL 3448
T+ Y C PG+ + HRV C D TW G P+C+A L+ P P + P+ K
Sbjct: 2973 TVTYQCVPGYMM---ESHRVSVLSCTKDRTWNGTKPVCKA----LMCKPPPLI--PNGK- 3022
Query: 3449 SVPDDVFAQNYIWKGSYNF 3467
V +++W S +
Sbjct: 3023 -----VVGSDFMWGSSVTY 3036
Score = 954 bits (2465), Expect = 0.0
Identities = 764/2709 (28%), Positives = 1161/2709 (42%), Gaps = 370/2709 (13%)
Query: 1017 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1076
SH + C + GP+GT+ SPG+P YPN NCTWT+ +Q F +F LE+
Sbjct: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
Query: 1077 HHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
D L + + + L RLTG LP TI + LR ISD+++S +GF+ T+
Sbjct: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATI---VSAATTLSLRLISDYAVSAQGFHATYE 132
Query: 1136 EYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR--VWSAP 1193
C +PG G + G F +GD + +SC+ G+ LEG + + C G W P
Sbjct: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
Query: 1194 LPRCVAE--CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1251
LP C A+ CG + GI+ SP++P Y NN +C ++I + G I + F L G
Sbjct: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
Query: 1252 -DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY---T 1307
D L++ + + FTGAS+ +SS N L L F SD GF Y
Sbjct: 253 YDFLEVTGTEGSSLW----FTGASLPAPVISS-KNWLRLHFTSDGNHRQRGFSAQYQVKK 307
Query: 1308 SFEL-----------------------------SHCEDPGIPQFGYKISDQGHFAGSTII 1338
EL + C DPGIP+ G ++ GS++
Sbjct: 308 QIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL-GSSVQ 366
Query: 1339 YGCNPGYTLHGSSLLKCM--TGERRAWDYPLPSCIAE-CGGRFKGESSGRILSPGYPFPY 1395
+ CN GY L GS + CM + AW P C A C +G SG I SP +P Y
Sbjct: 367 FTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG-PSGIITSPNFPIQY 425
Query: 1396 DNNLRCMWMI-EVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM--LLKEISGSLIPE 1452
DNN C+W+I ++P ++ L F FD E +D L V DG + D +L ++G+ +P+
Sbjct: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
Query: 1453 GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVF 1512
I ST + + + F TD S GF + +C DPG+P G R G GDT+ F
Sbjct: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKF 545
Query: 1513 QCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR 1572
+C P +EL G++ ITC Q N+ W P C+ C N T SG +LSPN+P Y +
Sbjct: 546 ECQPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
Query: 1573 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSN 1632
C W I + I LAF +EP +DFL I DG + +P++G+F ++LP I SS +
Sbjct: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
Query: 1633 TMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYV 1692
L F++D S GF++ + C DPG +NG R G +LGS++++ CD G++
Sbjct: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
Query: 1693 -LQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYS 1751
QG T+TC++ +G WN A+ C APCG T GT+LSP +P Y +C +
Sbjct: 723 GTQGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWV 781
Query: 1752 IAVPKEFVVFGQFVFFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITI 1810
I + + F F+T + +D +EV DG T + L+ G+ + L +S+ N + +
Sbjct: 782 IEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYL 840
Query: 1811 RFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYIL 1870
F++ + GF Y+ + S C P G+R GN+F VG+ V F C+ GY L
Sbjct: 841 LFSTDKSHSDIGFQLRYETI-TLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
Query: 1871 HGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKIT 1930
+ CE PN QW+ +LP+C CGG + GTILSPG+P+ Y NNLNC W I
Sbjct: 900 SDGEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIE 955
Query: 1931 VPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQ 1990
G G+ +F E D L + G P L +G+ +P + S LY NF
Sbjct: 956 TSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPI---SAGLYGNFT 1011
Query: 1991 ------SDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 2044
SD S+S GF++ ++ L+ C EP+ P+ I+ G ++ VGD ++F C GY L
Sbjct: 1012 AQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRL 1071
Query: 2045 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2104
+G + ITC+ G R W+ P+P C+A+CG +++ G +LSP FP NY ++ +C ++I
Sbjct: 1072 EGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
Query: 2105 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHS 2163
G G+ L+ F D L+V G++ ++ ++G S ++ +L ST+ L F +
Sbjct: 1132 PGKGIQLKARAFELSE-GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
Query: 2164 DYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND-FTVGQTISFECFPGYTLIGNSAL 2222
D +GF + + +++L C DP + G+ + ++ G ++SF C PGY+L G+ L
Sbjct: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
Query: 2223 TCLHGVSRNWNHPLPRCEALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2281
CL G R W+ PLP C A CGG + ++G + SPGYP Y + +C W + G I
Sbjct: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTI 1310
Query: 2282 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS- 2340
++F V TE ++D + +WDGP ++ + + SG + ++ST N ++++F +DF TS
Sbjct: 1311 GLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSK 1370
Query: 2341 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTC-RL 2399
F + + C P N D +E GD +QC PG+ L G+A ++C ++
Sbjct: 1371 QGFAIQFSVSTATSCNDPGIPQNGS--RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
Query: 2400 GERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMF 2459
R +PP C + P +GVILSP YP+ YP + C W ++V Y I +
Sbjct: 1429 ENRFFWQPSPPTC--IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALV 1486
Query: 2460 VEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKG 2519
F E +D L +YDG + SP++ S G I S+ + +FL + +D + G
Sbjct: 1487 FNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG-RIESSSNSLFLAFRSDASVSNAG 1545
Query: 2520 FRIRYI---AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2576
F I Y C P S +G + + +L S V + C G+ + G S+ C G
Sbjct: 1546 FVIDYTENPRESCFDPGSIKNGTRVG-SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
Query: 2577 YHAWDAPVPACQA-------------ISCGIPKAPTNGGI------LTTDYLVGTRVTYF 2617
W+ P P C A +S P+ T+G I + DY+V + +F
Sbjct: 1605 KPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFF 1664
Query: 2618 ---------CNDGYRLSSKELTT-------------------------AVCQSDGTWSNH 2643
+DG+ S+ L++ + + G +
Sbjct: 1665 HTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
Query: 2644 NKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL--P 2701
PR C S+ R+ GS + V F C+ GY G IECL P
Sbjct: 1725 QAVPRTSATQCSSV-----PEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
Query: 2702 NGTWSWRNERPYCQIISCG-------------ELPTP-------------PNGNKIG--- 2732
W P C ++ CG P P P G I
Sbjct: 1780 GALAQWNVSAPTC-VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQV 1838
Query: 2733 ----TQTSYGSTAIF-----TCDLGFMLVGSAVRECLSS------------------GLW 2765
T+ ++ S +F T + G+ V L+S G
Sbjct: 1839 VSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFH 1898
Query: 2766 SESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD--HNW 2823
E +T L+ C P + NG GE Y D V +QC PG+ L G + C W
Sbjct: 1899 LEYKTVGLSS-CPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRW 1957
Query: 2824 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCN------IGY------------ 2865
+ P C+ CG + G GF N C+ +G+
Sbjct: 1958 NYPPPLCI-AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTE 2016
Query: 2866 -------LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRES-----KIEHGNF 2913
+ GP + R P + + + +S K+E+ +
Sbjct: 2017 PNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDL 2076
Query: 2914 TYGTVVFYDCNPGYFLFGSSVLICQPNGQ---------WDKPLPEC---IMIDCGHPGVP 2961
TY + FL G + + WD P C + +C P
Sbjct: 2077 TYSHQI------SSFLRGFDLSELERTNSTPPVAASYVWDLD-PGCEAYELQECPDPEPF 2129
Query: 2962 PNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQ--LNGHWSGSQPH----CSGDATGT 3015
N ++ G Y G +V + C L G TCQ N +W P C G+ T +
Sbjct: 2130 ANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSS 2189
Query: 3016 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCG 3075
G +PG S S+ + T I HG L +G + + G
Sbjct: 2190 NGTVYSPGFPSPYSSSQDCVWLI-----TVPIGHGVRLNLSLLQTEPSG---DFITIWDG 2241
Query: 3076 NPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGD 3135
T VF + + + S +L R G ++ + C
Sbjct: 2242 PQQTAPRLGVFT---RSMAKKTVQSSSNQVLLK--FHRDAATGGIFAIAFSAYPLTKCPP 2296
Query: 3136 PGIPANG--LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW---SGVMPTCRA 3190
P I N + +++ +G V Y C PG+T L G+ I TC + GT+ G P C
Sbjct: 2297 PTILPNAEVVTENEEFNIGDIVRYRCLPGFT--LVGNEILTCKL-GTYLQFEGPPPICE- 2352
Query: 3191 VTCPTPPQI--SNGRLEGTNFDWGFSISYICS------PGYELSF--------------- 3227
V CPT + S G + ++ + CS P Y +S
Sbjct: 2353 VHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFE 2412
Query: 3228 ---------------------PAVLTCVGNGT---WSGE---------VPQCLPKFCGDP 3254
P ++T N WS + + P +C P
Sbjct: 2413 IFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAP-YCSLP 2471
Query: 3255 GIPAQGKREGKSFIYQ-SEVSFSCNFPFILVGSSTRIC----QADGTWSGSSPHCIEPTQ 3309
P G G++ + F CN + LVG S IC Q WS + P C
Sbjct: 2472 RAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC---QA 2528
Query: 3310 TSCENPGVPRHGSQNNTFG--FQVGSVVQFHCKKGHLLQ--GSTTRTCLPDLTWS--GIQ 3363
SC P P++G FG + VG+ + C +G+ LQ T CL WS +
Sbjct: 2529 LSCGLPEAPKNGM---VFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP 2585
Query: 3364 PECIPHSCKQPET----PAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTW 3419
P+C+P +C + ++ L+ C PG++ G R C+++ W
Sbjct: 2586 PQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIR-CQANGKW 2644
Query: 3420 T--GKVPIC 3426
+ P C
Sbjct: 2645 SLGDSTPTC 2653
Score = 937 bits (2423), Expect = 0.0
Identities = 762/2585 (29%), Positives = 1118/2585 (43%), Gaps = 348/2585 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L +GTI SPG+P Y + +C WVI A+ I+I F F E YD L + DG
Sbjct: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDG 811
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE--ELQSSSCGNPG 142
+ G +P + ST + L ++D + S GF++ YE LQS C +PG
Sbjct: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPG 871
Query: 143 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
+P G +G F VG + +SC +GY L L C N W +P C A CG
Sbjct: 872 IPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN----FQWSRALPSCEA--LCG 925
Query: 203 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--EGS 260
G ++GSSG I SP FP+ Y NN +CTW I G + F F +E +DYL I GS
Sbjct: 926 GFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGS 985
Query: 261 -EPPTIWLSGMNIPPPI---ISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 316
P L+G +P PI + ++ F++D + Y GF+ T S +
Sbjct: 986 FTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNI----------TFSEYD 1035
Query: 317 LEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLR------NSGLDPNT 370
LE A ++ ++T E ++T L +S L
Sbjct: 1036 LEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCV 1095
Query: 371 SKDGLSPHPADTQSTRRRPRHAEQIERTKE-LAVVTHRVKKAIDFKSRGF--------KL 421
++ G S TQ T P E + + + K I K+R F K+
Sbjct: 1096 AECGNS--VTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV 1153
Query: 422 FPGKDNSNK----FSILNEGGI---KTASNL--------------------------CPD 448
+ G +NS + FS G+ T+S+L C D
Sbjct: 1154 YDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCED 1213
Query: 449 PGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKT 507
PG P+ G ++ + GS+V FSCD Y L+G++ + C ++ W P C V
Sbjct: 1214 PGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC--LSGERRTWDRPLPTC-VAE 1270
Query: 508 CGSNLQGP-SGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
CG ++G SG SP +P Y+ N C+W I A I ++F FD E +D L I
Sbjct: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEA-EAGCTIGLHFLVFDTEEVHDVLRIW 1329
Query: 567 DGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGD 626
DG + +L+ L+G +P + S + + L TD GF + + SC D
Sbjct: 1330 DGPV--ESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCND 1387
Query: 627 PGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC---QENNQWSANIPICIFPCLS 683
PG P G R GD + D F+C G+ L G I C + W + P CI PC
Sbjct: 1388 PGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGG 1447
Query: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 743
+ T P G +LSP+YPE Y C W + P I L FN F+LE +DFL + DG
Sbjct: 1448 DLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDS 1507
Query: 744 ESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINA 803
SP++G+F G+++P + S+S+ L L F++D S+S GF I Y C DPG N
Sbjct: 1508 LSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNG 1567
Query: 804 RRFGDNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 862
R G + +LGSS++ C G+ + +GT T++CIL DGK +W+ P C APCGG +
Sbjct: 1568 TRVGSDLKLGSSVTYYCHGGY-EVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGS 1626
Query: 863 SGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG----PNLL 918
GV+LSP +P Y C + + + + F F T LN DV+EVHDG LL
Sbjct: 1627 DGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-DVVEVHDGHSQHSRLL 1685
Query: 919 SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV-TVNTYSCLDPGIPV 977
S L GS+ G +P ++SN + + F+ GF Y++V + C P
Sbjct: 1686 SSLSGSHTGESLP---LATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPR 1742
Query: 978 HGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRG 1033
+G+R G DFS+G+ V F C+SGY L + C W+ PTC CGG++
Sbjct: 1743 YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
Query: 1034 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT-QP 1092
GTILSPG+PE Y NSLNC W + V G G+Q +F E + D L + + T
Sbjct: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
Query: 1093 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1152
L +G+ +P +N+ + + L F SD S+S GF++ + L C +P +P G
Sbjct: 1863 LGSFSGTTVPALLNS---TSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGV 1919
Query: 1153 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1212
+ G + + D ++F C GY L+G + I C+ G R W+ P P C+A+CG + EG++
Sbjct: 1920 KTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVI 1979
Query: 1213 LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFT 1271
LSP +P NY +N +C + I + G G +I F D ++I +G +T+ ++G F+
Sbjct: 1980 LSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFS 2039
Query: 1272 GASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY------------------------- 1306
G+ + +L STS++ + F+SD GF+L Y
Sbjct: 2040 GSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTN 2098
Query: 1307 -----------------TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1349
++EL C DP P + G+ G ++ + C PGY L G
Sbjct: 2099 STPPVAASYVWDLDPGCEAYELQECPDPE-PFANGIVRGAGYNVGQSVTFECLPGYQLTG 2157
Query: 1350 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1409
+L C G R WD+PLP C CGG S+G + SPG+P PY ++ C+W+I V
Sbjct: 2158 HPVLTCQHGTNRNWDHPLPKCEVPCGGNIT-SSNGTVYSPGFPSPYSSSQDCVWLITVPI 2216
Query: 1410 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDF 1469
G+ V L TE S D + +WDGP + L + S+ + + S+ N V ++F D
Sbjct: 2217 GHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRD- 2275
Query: 1470 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGRE--PGDTVVFQCDPGYELQGEERIT 1527
+ FAI FS+ T C P + N + E GD V ++C PG+ L G E +T
Sbjct: 2276 AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILT 2335
Query: 1528 CIQVENRYFWQPSPPVCIAPCGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYV 1585
C ++ ++ PP+C C N LT S+G ILS ++P YP + C W + V DY
Sbjct: 2336 C-KLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYN 2394
Query: 1586 ISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDS-KLPERIESSSNTMHLAFRSDGSV 1644
ISL F E YD I+DGP SPL+ + + P + SSSN+++L + SD +
Sbjct: 2395 ISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAY 2454
Query: 1645 SYTGFHLEYKAKLRESCFDPGNIMNGTRLGM-DYKLGSTVTYYCDAGYVLQGYSTLTCIM 1703
+ GF + Y A C P ++G LG + G ++ + C+AGY L G+S C
Sbjct: 2455 NRKGFKIRYSAPY---CSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTR 2511
Query: 1704 GDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFG 1762
G W+ A+P C A CG G V + K Y+VG +YS +
Sbjct: 2512 HPQGYHLWSEAIPLCQALSCGLPEAPKNGMV----FGKEYTVGTKAMYSCS--------- 2558
Query: 1763 QFVFFQTSLHDVVEVYDG--------PTQQSSL----LSSLSGSHSGESLPLSSGNQITI 1810
+ Q E D P Q + +SS+S H L + Q
Sbjct: 2559 EGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQA 2618
Query: 1811 RFTSVGPITAKGFHFVYQAVPRTSST---------------QCSSVPEPRFGRRIGNEFA 1855
+ I G+++ Q V R + C +P P G RIG
Sbjct: 2619 QLML---ICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV 2675
Query: 1856 VGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGY 1915
G++ +F CN GY L GS C + N L W+ S C+ G
Sbjct: 2676 YGATAIFSCNSGYTLVGSRVREC--MANGL--WSGSEVRCLAG-------------HCGT 2718
Query: 1916 PEPYDN------NLNCVWKITVPEGAG---IQVQVVSFATEHNWDSLD----FYDGGDNN 1962
PEP N N + + AG I + V +H+W G
Sbjct: 2719 PEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPG 2778
Query: 1963 APRLGSYSG---TTIPHLLNSTSNNLYLNFQSDISVSAAGF------HLEYTAIGLDSCP 2013
+P SG T + S L S G H T++G+ C
Sbjct: 2779 SPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGV--CG 2836
Query: 2014 EPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGG 2073
+P P+ GI++GD + G V+ F C+ G+ L+G S TC W+ P +CG
Sbjct: 2837 DPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQAN--GSWSGSQP----ECG- 2889
Query: 2074 AMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSE 2133
++S G PG PS+ ++ L FS+ ++ E R G
Sbjct: 2890 --------VISCGNPGT-PSNARVVFSDGLV-----------FSSSIVY---ECREGYYA 2926
Query: 2134 TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNG 2193
T G LS + ++ + L +C DP NG
Sbjct: 2927 T----GLLSRHCSVNGTWTGSDPECLVI---------------------NCGDPGIPANG 2961
Query: 2194 FVIGNDFTVGQTISFECFPGYTLIGN--SALTCLHGVSRNWNHPLPRCEAL-CGGNITAM 2250
+GNDF +T++++C PGY + + S L+C R WN P C+AL C
Sbjct: 2962 LRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTK--DRTWNGTKPVCKALMCKPPPLIP 3019
Query: 2251 NGTIYS--------------PGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDF 2296
NG + GY P C GNG + T +
Sbjct: 3020 NGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTC-------EGNGSW-------TGELPQC 3065
Query: 2297 ITVWDGPDQNSPQIG--QFSGNTALESVYSTSNQILIKF-------HSDFTTSGFFVLSY 2347
V+ G D P G + G + SV + + L+ SD T SG S
Sbjct: 3066 FPVFCG-DPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSG-TQPSC 3123
Query: 2348 HAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG 2407
L C P VP I +++G + ++C G+ L G+ TC L G
Sbjct: 3124 IDPTLTTC-ADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCL--PNLTWSG 3180
Query: 2408 APPVC 2412
PP C
Sbjct: 3181 TPPDC 3185
Score = 398 bits (1022), Expect = e-110
Identities = 179/279 (64%), Positives = 220/279 (78%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
C L G NGT+ESPGFPYGYPN ANCTW I AEE++RIQ+VFQSFALEE++D LS++DG
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 144
P P N RTRLTGF LP + S + SLRL SD+AVSA GF YE L S +CGNPG
Sbjct: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
Query: 145 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 204
P G+ G+ F++GDK+RYSC G+ L+GH LTC A S N+A+WDFP+P CRA+DACGGT
Sbjct: 146 PNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGT 205
Query: 205 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 264
+RG SGIISSP FP+EYHNNADCTWTI+AE GDTI+L+F DFQ+E+ YD+LE+ G+E +
Sbjct: 206 LRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSS 265
Query: 265 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
+W +G ++P P+IS+KNWLRLHF +D NHR RGFSA YQ
Sbjct: 266 LWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
Score = 193 bits (490), Expect = 3e-48
Identities = 110/313 (35%), Positives = 155/313 (49%), Gaps = 16/313 (5%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
+ CGG L GTI SPGFP Y N NC W I+ E IQI SF E+ +D L +
Sbjct: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
Query: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
+DG + +G +P + ST + L SD +VSA GF + Y+ + SSC P
Sbjct: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEP 1912
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
VP GV G R+ V D + + C GY L GH ++C+ +V W++P P+C A+ C
Sbjct: 1913 AVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVR--RWNYPPPLCIAQ--C 1968
Query: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSE 261
GGT+ G+I SP FP Y +N DC+W I G + F +F E +DY+EI
Sbjct: 1969 GGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGP 2028
Query: 262 PPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTST--- 314
T + SG +P ++S + ++F +D + GF YQ T +H S+
Sbjct: 2029 YETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ-DLTYSHQISSFLR 2087
Query: 315 ----GELEEHNRT 323
ELE N T
Sbjct: 2088 GFDLSELERTNST 2100
Score = 184 bits (466), Expect = 2e-45
Identities = 113/318 (35%), Positives = 160/318 (50%), Gaps = 44/318 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGGTL+G +G I SP FP Y N A+CTW I+AE + I +VF F LE+ YD+L +
Sbjct: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGT 261
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-----ELQS---- 135
F TG LP PV S+K+ L TSD GF Y+ EL+S
Sbjct: 262 EGSSLWF----TGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVK 317
Query: 136 -----------------------SSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDG 172
+ C +PG+P +G G+ F +G ++++C GY L G
Sbjct: 318 LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQG 377
Query: 173 HPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIV 232
++TC+ S A+W P+CRA C +RG SGII+SP+FP +Y NNA C W I
Sbjct: 378 SKRITCMKVSDMFAAWSDHRPVCRAR-MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT 436
Query: 233 A-EPGDTISLIFTDFQMEEKYDYLEI-----EGSEPPTIW-LSGMNIPPPIISNKNWLRL 285
A P I L F +F +E YD L + +G + ++ L+G ++P I+S + + L
Sbjct: 437 ALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWL 496
Query: 286 HFVTDSNHRYRGFSAPYQ 303
F TD + GF A Y+
Sbjct: 497 LFQTDGSGSSLGFKASYE 514
Score = 165 bits (418), Expect = 7e-40
Identities = 98/285 (34%), Positives = 146/285 (51%), Gaps = 13/285 (4%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLYD 83
C L+G +G I SP FP Y N A+C W+I A ++ I++ F+ F LE YD L++ D
Sbjct: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGD 464
Query: 84 GHPHPTNFRTR--LTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
G LTG +P + ST L +D + S+ GFK YEE++ SCG+P
Sbjct: 465 GGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDP 524
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
G+P G G+RF GD +++ C + L G +TC N+ W P C +C
Sbjct: 525 GIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNN----QWSAKKPGC--VFSC 578
Query: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG-- 259
SG++ SP++P +Y N+ C W I+A P I L F D +E ++D+L I+
Sbjct: 579 FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGA 638
Query: 260 -SEPPTI-WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
+E P + SG +P I S+ + RL F TD + RGF+ +
Sbjct: 639 TAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683
Score = 157 bits (398), Expect = 1e-37
Identities = 88/289 (30%), Positives = 135/289 (46%), Gaps = 8/289 (2%)
Query: 20 GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYL 79
G +++C +G + SP +P Y N +C W+I+A +RI + F +E ++D+L
Sbjct: 573 GCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFL 632
Query: 80 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
+ DG +G LP +TS+ V L +D + GF + + + + C
Sbjct: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAE 198
+PGVP G +G +G I + C G++ G +TC+ + W+ V R E
Sbjct: 693 DPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKE-GSVVWNSAV--LRCE 749
Query: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
CGG + SG I SP +P Y + C W I A+PG I + F F+ E YD LE+
Sbjct: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809
Query: 259 G----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
S P G +P +IS N+L L F TD +H GF Y+
Sbjct: 810 DGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYE 858
Score = 133 bits (335), Expect = 3e-30
Identities = 75/218 (34%), Positives = 103/218 (47%), Gaps = 3/218 (1%)
Query: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
I CGG L G +G I SP +P YP G C W + I +VF F LE YD+L +
Sbjct: 1442 IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHI 1501
Query: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
YDG + G LP + S+ + L SD +VS GF + Y E SC +P
Sbjct: 1502 YDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDP 1561
Query: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
G G G+ +G + Y C GY ++G L+CI W+ P P+C A C
Sbjct: 1562 GSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA--PC 1619
Query: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTI 239
GG GS G++ SP++P Y + C + V P D +
Sbjct: 1620 GGQYVGSDGVVLSPNYPQNYTSGQICLY-FVTVPKDYV 1656
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 521 bits (1341), Expect = e-147
Identities = 391/1329 (29%), Positives = 559/1329 (42%), Gaps = 142/1329 (10%)
Query: 2184 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL- 2242
C P NG G +TVG ++F C GY L+G + +TCL S WNH +P C+A+
Sbjct: 1789 CKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLE--SGEWNHLIPYCKAVS 1846
Query: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDC--FWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2300
CG NG I + C + + + N + + P+ + +
Sbjct: 1847 CGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKC- 1905
Query: 2301 DGPDQNSPQIGQFSGNTALESV-YSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQP 2357
P+ + SG T L + YS ++ S + T SG + + A L C
Sbjct: 1906 SSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1965
Query: 2358 PPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRL-GERLQMD--------GA 2408
PP + +A I + F + + Y C G+TL G + C G+ + D
Sbjct: 1966 PPAIKDAVI--TGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2023
Query: 2409 PPVCQVLCPANELRL--DSTGVILSPGYPDSYPNLQMC----AWSISVEKGYNITMFVEF 2462
PP+ P RL D S GY + + +C W +G ++ +
Sbjct: 2024 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKW--VPPEGQDMPRCIAH 2081
Query: 2463 FQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITS-NGHEVFL-------------Q 2508
F EK P++ +L S+S +A ++ S E F+ Q
Sbjct: 2082 F-CEKP---------PSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQ 2131
Query: 2509 WSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSA 2568
W N I+ I C P S +GY S + ++V ++C++GF + G+ +
Sbjct: 2132 W------NPSPMSIQCIPVRCGEPPSIMNGY-ASGSNYSFGAMVAYSCNKGFYIKGEKKS 2184
Query: 2569 VCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSK 2627
C + W +P+P C +SCG P NG + TT + + V Y CN GY+ S
Sbjct: 2185 TCEATG----QWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYK--SV 2238
Query: 2628 ELTTAVCQSDGTWSNHNKTP-RCVVVTC----PSINSFILEHGRWRIVNGSHYEYKTKVV 2682
VCQ++ W H+++P CV + C P N F + G ++E +KV
Sbjct: 2239 GSPVFVCQANRHW--HSESPLMCVPLDCGKPPPIQNGF---------MKGENFEVGSKVQ 2287
Query: 2683 FSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAI 2742
F C+ GY +G +S C +G W+ + P C C E P N + T+
Sbjct: 2288 FFCNEGYELVGDSSWTCQKSGKWN-KKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVT 2346
Query: 2743 FTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN-YGYRDTVVY 2801
F+C G +L G +V +CL S W++S C C P LI G I + + TV Y
Sbjct: 2347 FSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKY 2406
Query: 2802 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSC 2861
C GF L G+S +CQ D WS LP CVPV C P G G + ++C
Sbjct: 2407 SCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTC 2466
Query: 2862 NIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFY 2921
G+ + G T C N W P CK + C P N K + + YG V Y
Sbjct: 2467 KPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILN----GKFSYTDLHYGQTVTY 2522
Query: 2922 DCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSC 2981
CN G+ L G S L C G WD P C I C P N + G Y++G+ + YSC
Sbjct: 2523 SCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSC 2582
Query: 2982 TGKRSLLGQSSRTCQLNGHWSGSQPHCS------------GDATGTCGDPG--------- 3020
+ G + +TC+ +G WS S P C GD T D G
Sbjct: 2583 FPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMM 2641
Query: 3021 ----------------------TPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLA 3058
T + SNF + V Y C+ GY L G+ C
Sbjct: 2642 EVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQE 2701
Query: 3059 NGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTAN 3118
+G+W G P C +++C P NG R T+ S+V YSC G+IL+G +R C N
Sbjct: 2702 DGTWNGSAPSCISIECDLPTAPENG-FLRFTETSMGSAVQYSCKPGHILAGSDLRLCLEN 2760
Query: 3119 GTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN 3178
WSG P C ISC P NG G +Y + Y C PGY LNG+ RTC +
Sbjct: 2761 RKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYV--LNGTERRTCQDD 2818
Query: 3179 GTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT 3238
W P C V C +PP +NG++ G + + I Y C+ G+ L C+ NG+
Sbjct: 2819 KNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGS 2878
Query: 3239 WSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWS 3298
WSG P C+P C P A G EG + + EV+F C+ +IL G+ CQ+DG W
Sbjct: 2879 WSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWD 2938
Query: 3299 GSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLT 3358
P C +C P HG N F F G +Q+ C G+ L G+++R CL + +
Sbjct: 2939 AEIPLC---KPVNCGPPEDLAHGFPNG-FSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGS 2994
Query: 3359 WSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT 3418
WSG P C+P C P + V G D G C GF L G +E C +D
Sbjct: 2995 WSGSSPSCLPCRCSTP-VIEYGTVNGTDFDC-GKAARIQCFKGFKLLGLSE-ITCEADGQ 3051
Query: 3419 WTGKVPICE 3427
W+ P CE
Sbjct: 3052 WSSGFPHCE 3060
Score = 494 bits (1271), Expect = e-139
Identities = 335/1075 (31%), Positives = 480/1075 (44%), Gaps = 119/1075 (11%)
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDI----IRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2410
C PP V N + E G I +RYQC PG+ VG+ + C+ + +P
Sbjct: 2204 CGEPPKVENGFL-----EHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSE-SPL 2257
Query: 2411 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2470
+C V L G P N M + + + V+FF E
Sbjct: 2258 MC---------------VPLDCGKPPPIQNGFMKG------ENFEVGSKVQFFCNEG--- 2293
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
L GD S++ +G +W NKK + + C
Sbjct: 2294 ---------------YELVGD--SSWTCQKSG-----KW------NKKS-NPKCMPAKCP 2324
Query: 2531 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2590
P + ++ + ++ VV ++C G L G S C S W+ P C+ +
Sbjct: 2325 EPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQ----WNDSFPVCKIV 2379
Query: 2591 SCGIPKAPTNGGILTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2649
C P + G + + L G+ V Y C G+ L +T +CQ DGTWS+ P C
Sbjct: 2380 LCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGN--STTLCQPDGTWSS--PLPEC 2435
Query: 2650 VVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRN 2709
V V CP + +G I++ Y + +++C PG+ +G + C NG W
Sbjct: 2436 VPVECPQPEE--IPNG---IIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENG--HWLG 2488
Query: 2710 ERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESE 2769
+P C+ I C + NG T YG T ++C+ GF L G + CL +G W
Sbjct: 2489 GKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDA 2548
Query: 2770 TRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2829
C A HC P+ I NG V G +Y Y ++Y C PGF++ G +++ C++ WS +P+
Sbjct: 2549 PSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEES-GWSSSIPT 2607
Query: 2830 CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2889
C+P+ CG P +F D + GY Q + HPP
Sbjct: 2608 CMPIDCGLPPH----------IDFGDCTKLKDDQGYFEQEDD--MMEVPYVTPHPPYHLG 2655
Query: 2890 VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2949
V + N+K NF YGT+V Y CNPGY L G+ VLICQ +G W+ P
Sbjct: 2656 AVAKTWE----NTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPS 2711
Query: 2950 CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS 3009
CI I+C P P N L + + GS V YSC L G R C N WSG+ P C
Sbjct: 2712 CISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCE 2771
Query: 3010 GDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3069
+C P +GS + SN+ ST+ Y CD GY+L+G+E RTC + +W +P C
Sbjct: 2772 AI---SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Query: 3070 KAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3129
V C +P +ANG+V R D TF + Y+C EG++L G R C ANG+WSG P+C
Sbjct: 2829 IPVDCSSPPVSANGQV-RGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCV 2887
Query: 3130 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR 3189
+ C P ANG+ G DY + V++ C GY L+G+ TC +G W +P C+
Sbjct: 2888 PVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYI--LHGAPKLTCQSDGNWDAEIPLCK 2945
Query: 3190 AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPK 3249
V C P +++G G +F G I Y C PGY+L + C+ NG+WSG P CLP
Sbjct: 2946 PVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPC 3005
Query: 3250 FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3309
C P I G G F C F L+G S C+ADG WS PHC
Sbjct: 3006 RCSTPVI-EYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHC---EH 3061
Query: 3310 TSCEN-PGVPRHGSQNNTFGFQVGS----VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3364
TSC + P +P N F + S V+ + C+ G+++QGS+ C WS P
Sbjct: 3062 TSCGSLPMIP------NAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYP 3115
Query: 3365 ECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTW 3419
C P SC P + A+A G + ++ + C G+ + T+ C+ D W
Sbjct: 3116 VCEPLSCGSPPSVANAVATG-EAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRW 3169
Score = 458 bits (1178), Expect = e-128
Identities = 327/1164 (28%), Positives = 486/1164 (41%), Gaps = 146/1164 (12%)
Query: 2346 SYHAYQLRVCQPPP------PVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRL 2399
S+ ++ +C PPP P+P++ + G ++Y C+ GF L GN+ C
Sbjct: 2372 SFPVCKIVLCTPPPLISFGVPIPSSAL-------HFGSTVKYSCVGGFFLRGNSTTLC-- 2422
Query: 2400 GERLQMDGA-----PPVCQVLCPANE------------LRLDSTGVILSPGYPDSYPNLQ 2442
Q DG P V CP E L + PG+
Sbjct: 2423 ----QPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTT 2478
Query: 2443 MCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQSPVLISLSGDYSSAFNI 2498
+C + G +E + ++ +F ++ G + + SA
Sbjct: 2479 LCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTC 2538
Query: 2499 TSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDR 2558
G W D + A +C +P+ +G++ +++ ++C
Sbjct: 2539 LETG-----DWDVDAPSCN--------AIHCDSPQPIENGFV-EGADYSYGAIIIYSCFP 2584
Query: 2559 GFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPK---------------------- 2596
GF++ G + C +S W + +P C I CG+P
Sbjct: 2585 GFQVAGHAMQTCEESG-----WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDD 2639
Query: 2597 ----------APTNGGIL--------------TTDYLVGTRVTYFCNDGYRLSSKELTTA 2632
P + G + ++++L GT V+Y CN GY L +
Sbjct: 2640 MMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVL-- 2697
Query: 2633 VCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGL 2692
+CQ DGTW+ P C+ + C + E+G R S + V +SC PG+
Sbjct: 2698 ICQEDGTWNG--SAPSCISIECDLPTA--PENGFLRFTETS---MGSAVQYSCKPGHILA 2750
Query: 2693 GPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLV 2752
G CL N WS + P C+ ISC + NG+ G+ +Y ST + CD G++L
Sbjct: 2751 GSDLRLCLENRKWSGAS--PRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLN 2808
Query: 2753 GSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS 2812
G+ R C W E E C+ C P + NGQV G+ Y ++ + Y CN GF L G+
Sbjct: 2809 GTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGA 2868
Query: 2813 SVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK 2872
R+C + +WSG P CVPV C P G T G + F VTF C+ GY++ G K
Sbjct: 2869 RSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPK 2928
Query: 2873 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHG-----NFTYGTVVFYDCNPGY 2927
CQ++ W P+CK VNC P + HG +F +G + Y C PGY
Sbjct: 2929 LTCQSDGNWDAEIPLCKPVNCGPP---------EDLAHGFPNGFSFIHGGHIQYQCFPGY 2979
Query: 2928 FLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSL 2987
L G+S C NG W P C+ C P + V +G + G C L
Sbjct: 2980 KLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTV-NGTDFDCGKAARIQCFKGFKL 3038
Query: 2988 LGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYI 3047
LG S TC+ +G WS PHC + G+ P P + S+++ ++ + Y+C +GY+
Sbjct: 3039 LGLSEITCEADGQWSSGFPHCEHTSCGSL--PMIPNAFISETSSWK-ENVITYSCRSGYV 3095
Query: 3048 LHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYIL 3107
+ GS + C G W+ P C+ + CG+P + AN V + T+ S V C+EGY +
Sbjct: 3096 IQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANA-VATGEAHTYESEVKLRCLEGYTM 3154
Query: 3108 -SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTME 3166
+ C +G W +C+ C P + L +GDD+ V + VS C GYT E
Sbjct: 3155 DTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFE 3214
Query: 3167 LNGSRIRTCTINGTWSGVMP--TCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYE 3224
G I C ++GTW +C V+C P +G + G+ + + +I Y C PGYE
Sbjct: 3215 --GVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYE 3272
Query: 3225 LSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILV 3284
L C N WSG V C C P GK + ++ V +SCN + L
Sbjct: 3273 LEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLE 3332
Query: 3285 GSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHL 3344
G S C +GTWS P C C P V + + F V V C++G L
Sbjct: 3333 GPSEAHCTENGTWSHPVPLC---KPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFL 3389
Query: 3345 LQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFL 3404
LQG TC PD TW+ +C SC P +A G+ +G + Y+C G+ L
Sbjct: 3390 LQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHY-QYGDMITYSCYSGYML 3448
Query: 3405 AGGTEHRVCRSDNTWTGKVPICEA 3428
G VC + TWT PIC A
Sbjct: 3449 EGFL-RSVCLENGTWTSP-PICRA 3470
Score = 437 bits (1123), Expect = e-121
Identities = 285/926 (30%), Positives = 402/926 (43%), Gaps = 71/926 (7%)
Query: 2550 SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYL 2609
S V CD GF+LVG C W P+P C+ ISCG+P NG D+
Sbjct: 1652 SKVNLFCDPGFQLVGNPVQYCLNQGQ----WTQPLPHCERISCGVPPPLENGFHSADDFY 1707
Query: 2610 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRI 2669
G+ VTY CN+GY L + C +G+W+ +P C+ V ++ S EH
Sbjct: 1708 AGSTVTYQCNNGYYLLGD--SRMFCTDNGSWNG--VSPSCLDVDECAVGSDCSEHASCLN 1763
Query: 2670 VNGSH------------------------------------YEYKTKVVFSCDPGYHGLG 2693
V+GS+ Y +V FSC GY +G
Sbjct: 1764 VDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMG 1823
Query: 2694 PASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVG 2753
I CL +G W+ + PYC+ +SCG+ P NG ++GS + C+ G+ L G
Sbjct: 1824 VTKITCLESGEWN--HLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAG 1881
Query: 2754 SAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSS 2813
CL++ WS S C C PE I NG+ I Y T Y C+ G+ L G S
Sbjct: 1882 DKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPS 1941
Query: 2814 VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKA 2873
+ C W P+C V CG P + +GN F F + VT++C GY + G
Sbjct: 1942 IIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTI 2001
Query: 2874 QCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSS 2933
+C A+ +WS C V+C +P I ++ E+ + +G + FY C+ GY L +S
Sbjct: 2002 ECLADGKWSRSDQQCLAVSCDEPPIVDHASPET----AHRLFGDIAFYYCSDGYSLADNS 2057
Query: 2934 VLICQPNGQWDKP----LPECIMIDCGHPGVPPNAVL---SGEKYTFGSTVHYSCTGKRS 2986
L+C G+W P +P CI C P ++L S K+ GS V + C
Sbjct: 2058 QLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFV 2117
Query: 2987 LLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGY 3046
L + C G W+ S P CG+P + +G SN+ + V Y+C+ G+
Sbjct: 2118 LNTSAKIECMRGGQWNPS-PMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGF 2176
Query: 3047 ILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYI 3106
+ G ++ TC A G W+ P C V CG P NG + G F S V Y C GY
Sbjct: 2177 YIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYK 2236
Query: 3107 LSGPSVRQCTANGTWSGTLP-NCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTM 3165
G V C AN W P C + CG P NG G+++ VG V + C GY
Sbjct: 2237 SVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGY-- 2294
Query: 3166 ELNGSRIRTCTINGTWSGVM-PTCRAVTCPTPPQISNGR-LEGTNFDWGFSISYICSPGY 3223
EL G TC +G W+ P C CP PP + N L+ + G +++ C G+
Sbjct: 2295 ELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGV-VTFSCKEGH 2353
Query: 3224 ELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFI-YQSEVSFSCNFPFI 3282
L P+VL C+ + W+ P C C P + + G S + + S V +SC F
Sbjct: 2354 VLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFF 2413
Query: 3283 LVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKG 3342
L G+ST +CQ DGTWS P C+ C P +G + G S + CK G
Sbjct: 2414 LRGNSTTLCQPDGTWSSPLPECV---PVECPQPEEIPNGI-IDVQGLAYLSTALYTCKPG 2469
Query: 3343 HLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGF 3402
L G+TT C + W G +P C C +P+ + DL +G T+ Y+C GF
Sbjct: 2470 FELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDL-HYGQTVTYSCNRGF 2528
Query: 3403 FLAGGTEHRVCRSDNTWTGKVPICEA 3428
L G + C W P C A
Sbjct: 2529 RLEGPSA-LTCLETGDWDVDAPSCNA 2553
Score = 379 bits (974), Expect = e-104
Identities = 333/1226 (27%), Positives = 494/1226 (40%), Gaps = 154/1226 (12%)
Query: 2203 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPD 2261
G T+ + C G+ L GNS C W+ PLP C + C NG I G
Sbjct: 2401 GSTVKYSCVGGFFLRGNSTTLCQP--DGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAY 2458
Query: 2262 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI----------G 2311
C PG + N T L E + W G I G
Sbjct: 2459 LSTALYTC------KPGFELVGNTTTLCGENGH-----WLGGKPTCKAIECLKPKEILNG 2507
Query: 2312 QFS------GNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQLRVCQPPPPVPN 2363
+FS G T YS + ++ S T +G + + + C P P+ N
Sbjct: 2508 KFSYTDLHYGQTV---TYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIEN 2564
Query: 2364 AEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVL---CPANE 2420
+ E ++ G II Y C PGF + G+A+ TC E + P C + P +
Sbjct: 2565 GFV--EGADYSYGAIIIYSCFPGFQVAGHAMQTC---EESGWSSSIPTCMPIDCGLPPHI 2619
Query: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----------FD 2470
D T + GY + ++ + ++ Y++ + ++ KE +
Sbjct: 2620 DFGDCTKLKDDQGYFEQEDDMMEVPY-VTPHPPYHLGAVAKTWENTKESPATHSSNFLYG 2678
Query: 2471 VLQVY------------------DGP-NIQSPVLISLSGDYSSA-------FNITSNGHE 2504
+ Y DG N +P IS+ D +A F TS G
Sbjct: 2679 TMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSA 2738
Query: 2505 VFLQWSADHGN------------NKK--GFRIRYIAFYCSTPESPPHGYIISQTGGQLNS 2550
V Q+S G+ N+K G R A C P +G I L S
Sbjct: 2739 V--QYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYL-S 2795
Query: 2551 VVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLV 2610
+ + CD G+ L G C+ WD P C + C P NG + +Y
Sbjct: 2796 TLYYECDPGYVLNGTERRTCQDDKN----WDEDEPICIPVDCSSPPVSANGQVRGDEYTF 2851
Query: 2611 GTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIV 2670
+ Y CN+G+ L + VC ++G+WS TP CV V C + L +G +
Sbjct: 2852 QKEIEYTCNEGFLLEGAR--SRVCLANGSWSG--ATPDCVPVRCATPPQ--LANG---VT 2902
Query: 2671 NGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNK 2730
G Y + +V F C GY G + C +G W E P C+ ++CG +G
Sbjct: 2903 EGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWD--AEIPLCKPVNCGPPEDLAHGFP 2960
Query: 2731 IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIG 2790
G +G + C G+ L G++ R CLS+G WS S CL C P +I G V G
Sbjct: 2961 NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP-VIEYGTVNG 3019
Query: 2791 ENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH-PGSPIYGRTSGN 2849
++ QC GF+L+G S C+ D WS P C SCG P P + +
Sbjct: 3020 TDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETS 3079
Query: 2850 GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIE 2909
+ N V+T+SC GY++QG + C WS P P+C+ ++C P AN+ +
Sbjct: 3080 SWKEN-VITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAH 3138
Query: 2910 HGNFTYGTVVFYDCNPGYFL-FGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSG 2968
TY + V C GY + + CQ +G+W C C P + ++ G
Sbjct: 3139 ----TYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHG 3194
Query: 2969 EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATG--TCGDPGTPGHGS 3026
+ ++ V SC + G + CQL+G W +P S ++ +CG P +P HG
Sbjct: 3195 DDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW---EPPFSDESCSPVSCGKPESPEHGF 3251
Query: 3027 RQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVF 3086
S + +ST+ Y C+ GY L G+ ER C N W+G CK +C P NGK
Sbjct: 3252 VVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKA- 3310
Query: 3087 RIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPG-IPANGLRY 3145
I+ T +V+YSC GY L GPS CT NGTWS +P C C P IP N L
Sbjct: 3311 DIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLS 3370
Query: 3146 GDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLE 3205
++ V QNVS C+ G+ ++ +G I TC + TW+ C ++C P + N
Sbjct: 3371 EKEFYVDQNVSIKCREGFLLQGHG--IITCNPDETWTQTSAKCEKISCGPPAHVENAIAR 3428
Query: 3206 GTNFDWGFSISYICSPGYELSFPAVLTCVGNGTW-SGEVPQCLPKF-CGDPGIPAQGKRE 3263
G ++ +G I+Y C GY L C+ NGTW S + + + +F C + GI +R
Sbjct: 3429 GVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGI---CQRP 3485
Query: 3264 GKSFIYQSEVSFSCNFPFILVGS-------STRICQADGTWSGSSPH------------- 3303
+ + C P ++ + C W+GS H
Sbjct: 3486 NACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGK 3545
Query: 3304 CIEPTQTSCENPGVPRHGSQNNTFGF 3329
C+ P + C + + S+ GF
Sbjct: 3546 CVRPNRCHCLSSWTGHNCSRKRRTGF 3571
Score = 360 bits (925), Expect = 1e-98
Identities = 240/766 (31%), Positives = 330/766 (43%), Gaps = 79/766 (10%)
Query: 2738 GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRD 2797
GS CD GF LVG+ V+ CL+ G W++ C CG+P + NG +++
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGS 1710
Query: 2798 TVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCV-------------------------- 2831
TV YQCN G+ L+G S C + +W+G PSC+
Sbjct: 1711 TVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYIC 1770
Query: 2832 ---------------PVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQ 2876
P+ C PG+P G +SG + VTFSC GY + G TK C
Sbjct: 1771 SCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCL 1830
Query: 2877 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2936
+ +W+H P CK V+C P IP N IE FT+G+ V Y CN GY L G
Sbjct: 1831 ESGEWNHLIPYCKAVSCGKPAIPEN----GCIEELAFTFGSKVTYRCNKGYTLAGDKESS 1886
Query: 2937 CQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRT 2994
C N W P C + C P N +LSG T+ ST YSC SL G S
Sbjct: 1887 CLANSSWSHSPPVCEPVKCSSPENINNGKYILSG--LTYLSTASYSCDTGYSLQGPSIIE 1944
Query: 2995 CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEER 3054
C +G W + P C CG+P +NF ++TV Y C GY L G +
Sbjct: 1945 CTASGIWDRAPPACH---LVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTI 2001
Query: 3055 TCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQ 3114
CLA+G W+ +C AV C P + F Y C +GY L+ S
Sbjct: 2002 ECLADGKWSRSDQQCLAVSCDEPPIVDHASP-ETAHRLFGDIAFYYCSDGYSLADNSQLL 2060
Query: 3115 CTANGTW----SGTLPNCTIISCGDPGIPANGLRYG---DDYVVGQNVSYMCQPGYTMEL 3167
C A G W +P C C P + + + G VS+ C G+ L
Sbjct: 2061 CNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFV--L 2118
Query: 3168 NGSRIRTCTINGTW--SGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYEL 3225
N S C G W S + C V C PP I NG G+N+ +G ++Y C+ G+ +
Sbjct: 2119 NTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYI 2178
Query: 3226 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILV 3284
TC G WS +P C P CG+P G E + I++SEV + CN + V
Sbjct: 2179 KGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSV 2238
Query: 3285 GSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHL 3344
GS +CQA+ W SP P C P ++G F+VGS VQF C +G+
Sbjct: 2239 GSPVFVCQANRHWHSESPLMCVP--LDCGKPPPIQNGFMKGE-NFEVGSKVQFFCNEGYE 2295
Query: 3345 LQGSTTRTCLPDLTWS-GIQPECIPHSCKQPETPAHAN-VVGMDLPSHGYTLIYTCQPGF 3402
L G ++ TC W+ P+C+P C PE P N +V +L + + ++C+ G
Sbjct: 2296 LVGDSSWTCQKSGKWNKKSNPKCMPAKC--PEPPLLENQLVLKELTTEVGVVTFSCKEGH 2353
Query: 3403 FLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP--ALGTPSP 3446
L G + + C W P+C KI++ P P + G P P
Sbjct: 2354 VLQGPSVLK-CLPSQQWNDSFPVC----KIVLCTPPPLISFGVPIP 2394
Score = 301 bits (772), Expect = 6e-81
Identities = 193/638 (30%), Positives = 279/638 (43%), Gaps = 67/638 (10%)
Query: 2839 GSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGI 2898
GS + RT+ V C+ G+ + G C QW+ P P C+ ++C P
Sbjct: 1636 GSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPP 1695
Query: 2899 PANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMID---- 2954
N + +F G+ V Y CN GY+L G S + C NG W+ P C+ +D
Sbjct: 1696 LENGFHSA----DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAV 1751
Query: 2955 -------------------------------------CGHPGVPPNAVLSGEKYTFGSTV 2977
C PG P N SGE YT G+ V
Sbjct: 1752 GSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEV 1811
Query: 2978 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKST 3037
+SC L+G + TC +G W+ P+C +CG P P +G +E F S
Sbjct: 1812 TFSCQEGYQLMGVTKITCLESGEWNHLIPYCK---AVSCGKPAIPENGCIEELAFTFGSK 1868
Query: 3038 VRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSV 3097
V Y C+ GY L G +E +CLAN SW+ P C+ V+C +P NGK + + G T+ S+
Sbjct: 1869 VTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK-YILSGLTYLSTA 1927
Query: 3098 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSY 3157
YSC GY L GPS+ +CTA+G W P C ++ CG+P + + G+++ V+Y
Sbjct: 1928 SYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTY 1987
Query: 3158 MCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISY 3217
C+ GYT L G C +G WS C AV+C PP + + E + +G Y
Sbjct: 1988 TCKEGYT--LAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFY 2045
Query: 3218 ICSPGYELSFPAVLTCVGNGTW----SGEVPQCLPKFCGDPGIPAQGKREGKS---FIYQ 3270
CS GY L+ + L C G W ++P+C+ FC P + E S F
Sbjct: 2046 YCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAG 2105
Query: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQ 3330
S VSF C F+L S+ C G W+ SP I+ C P +G + + +
Sbjct: 2106 SVVSFKCMEGFVLNTSAKIECMRGGQWN-PSPMSIQCIPVRCGEPPSIMNGYASGS-NYS 2163
Query: 3331 VGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQP---ETPAHANVVGMDL 3387
G++V + C KG ++G TC WS P C P SC +P E + G
Sbjct: 2164 FGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIF 2223
Query: 3388 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPI 3425
S + Y C PG+ G VC+++ W + P+
Sbjct: 2224 ESE---VRYQCNPGYKSVGSPVF-VCQANRHWHSESPL 2257
Score = 270 bits (690), Expect = 2e-71
Identities = 446/2055 (21%), Positives = 711/2055 (34%), Gaps = 362/2055 (17%)
Query: 1161 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPL 1219
G + C G++L G CL G+ W+ PLP C CG G + ++
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQGQ--WTQPLPHCERISCGVPPPLENGFHSADDFYA 1708
Query: 1220 NYENNHECIYSIQVQAGKGINISARTFHLAQG----------DVLKIYDGKDKTTHLLGA 1269
++C G + +R F G DV + G D + H
Sbjct: 1709 GSTVTYQC------NNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHA--- 1759
Query: 1270 FTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQ 1329
+ ++ G + S + D + E + C+ PG P+ G+ S +
Sbjct: 1760 -SCLNVDGSYICSCVPP----YTGDGKNCAEPIK----------CKAPGNPENGHS-SGE 1803
Query: 1330 GHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSP 1389
+ G+ + + C GY L G + + C+ E W++ +P C A G+ +G I
Sbjct: 1804 IYTVGAEVTFSCQEGYQLMGVTKITCL--ESGEWNHLIPYCKAVSCGKPAIPENGCIEEL 1861
Query: 1390 GYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSL 1449
+ F RC + G LA D E+S W P +K S
Sbjct: 1862 AFTFGSKVTYRC------NKGYT-----LAGDKESSCLANSSWSHSPPVCEPVKCSS--- 1907
Query: 1450 IPEGIHSTLNIVT--IQFDTDFYISKSGFAIQFSSSVATA----------------CRDP 1491
PE I++ I++ T Y +G+++Q S + C +P
Sbjct: 1908 -PENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEP 1966
Query: 1492 GVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGN 1551
+ G+ +TV + C GY L G + I C+ W S C+A
Sbjct: 1967 PAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGK---WSRSDQQCLAVSCDE 2023
Query: 1552 LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDG---- 1607
P H P + + D +S+ N L G
Sbjct: 2024 ---------PPIVDHASPETAH-----RLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVP 2069
Query: 1608 -PDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV----SYTGFHLEYKAKLR---- 1658
+ P + K P S ++ A + GSV GF L AK+
Sbjct: 2070 PEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRG 2129
Query: 1659 --------------ESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMG 1704
C +P +IMNG G +Y G+ V Y C+ G+ ++G TC
Sbjct: 2130 GQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTC--- 2186
Query: 1705 DDGRPGWNRALPSCH-APCGSRSTGSEGTVLSPN---YPKNYSVGHNCVYSIAVPKEFVV 1760
+ W+ +P+CH CG G + + N Y FV
Sbjct: 2187 -EATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVC 2245
Query: 1761 FGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIR--FTSVGPI 1818
H + P +G GE+ + S Q + VG
Sbjct: 2246 QA-----NRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDS 2300
Query: 1819 T---AKGFHFVYQAVPRTSSTQCSSVPEPRF--GRRIGNEFAVGSSVL-FDCNPGYILHG 1872
+ K + ++ P+ +C PEP + + E V+ F C G++L G
Sbjct: 2301 SWTCQKSGKWNKKSNPKCMPAKC---PEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQG 2357
Query: 1873 SIAIRCETVPNSLAQWNDSLPTC-IVPC----------------------------GGIL 1903
++C +P+ QWNDS P C IV C GG
Sbjct: 2358 PSVLKC--LPSQ--QWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFF 2413
Query: 1904 TKRKGTILSP-----GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYD- 1957
+ T L P P + C +P G I VQ +++ + + ++
Sbjct: 2414 LRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGI-IDVQGLAYLSTALYTCKPGFEL 2472
Query: 1958 -------GGDN-----NAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSA-AGFHLEY 2004
G+N P + +LN + L++ ++ S GF LE
Sbjct: 2473 VGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEG 2532
Query: 2005 TA-----------IGLDSC-----PEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 2048
+ + SC PQ +G G Y G ++ + C G+ + GH+
Sbjct: 2533 PSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHA 2592
Query: 2049 HITCMPGPVRRWNYPIPICL-AQCG-GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIG 2106
TC W+ IP C+ CG DF G + D +
Sbjct: 2593 MQTCEES---GWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPH 2649
Query: 2107 FGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2166
HL V + E + S + T++ P + L D +
Sbjct: 2650 PPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPG-----YELLGNPVLICQEDGT 2704
Query: 2167 QNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH 2226
N + L + P+ NGF+ + ++G + + C PG+ L G+ CL
Sbjct: 2705 WNGSAPSCISIECDLPTAPE-----NGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLE 2759
Query: 2227 GVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINF 2285
+R W+ PRCEA+ C MNG+I Y + +C G +N
Sbjct: 2760 --NRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYEC--------DPGYVLNG 2809
Query: 2286 TVLQT----------EPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILI---K 2332
T +T EPI + P + Q+ E Y+ + L+ +
Sbjct: 2810 TERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGAR 2869
Query: 2333 FHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGN 2392
+ + +R C PP + N +TE ++ + + C G+ L G
Sbjct: 2870 SRVCLANGSWSGATPDCVPVR-CATPPQLANG--VTEGLDYGFMKEVTFHCHEGYILHGA 2926
Query: 2393 AILTCRLGERLQMDGAPPVCQ-VLC---------------------------PANELRLD 2424
LTC+ D P+C+ V C P +L +
Sbjct: 2927 PKLTCQSDG--NWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGN 2984
Query: 2425 STGVILSPG-YPDSYPNLQMCAWSISVEKGYNITMFVEF-------FQTEKEFDVLQVYD 2476
S+ LS G + S P+ C S V + Y +F Q K F +L +
Sbjct: 2985 SSRRCLSNGSWSGSSPSCLPCRCSTPVIE-YGTVNGTDFDCGKAARIQCFKGFKLLGL-- 3041
Query: 2477 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPP 2536
S + G +SS F +H + C + P
Sbjct: 3042 -----SEITCEADGQWSSGFP------------HCEHTS-------------CGSLPMIP 3071
Query: 2537 HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPK 2596
+ + IS+T +V+ ++C G+ + G S +C + W P P C+ +SCG P
Sbjct: 3072 NAF-ISETSSWKENVITYSCRSGYVIQGSSDLICTEKG----VWSQPYPVCEPLSCGSPP 3126
Query: 2597 APTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPS 2656
+ N + + V C +GY + + + T CQ DG W + C CP
Sbjct: 3127 SVANAVATGEAHTYESEVKLRCLEGYTMDT-DTDTFTCQKDGRWFPERIS--CSPKKCP- 3182
Query: 2657 INSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQI 2716
+ E+ +V+G + +V SC GY G C +GTW C
Sbjct: 3183 ----LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSP 3238
Query: 2717 ISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGH 2776
+SCG+ +P +G +G++ ++ ST I+ C+ G+ L G+ R C + WS C
Sbjct: 3239 VSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETR 3298
Query: 2777 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCG 2836
C P +NG+ EN VVY CN G+ L G S C ++ WS +P C P C
Sbjct: 3299 CETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCP 3358
Query: 2837 HP-GSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSD 2895
P P S F + V+ C G+L+QG C + W+ C+ ++C
Sbjct: 3359 VPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGP 3418
Query: 2896 PGIPANSKRESKIEHG-NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI- 2953
P + E+ I G ++ YG ++ Y C GY L G +C NG W P P C +
Sbjct: 3419 P-----AHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRAVC 3472
Query: 2954 --DCGHPGV--PPNAVLSGEKYTFGSTVHYSC-----TGKRSLLGQSSRTCQLNGHWSGS 3004
C + G+ PNA E + C G R + + C W+GS
Sbjct: 3473 RFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV---APYQCDCPPGWTGS 3529
Query: 3005 QPHCSGDATGTCGDP 3019
+ H T C P
Sbjct: 3530 RCH-----TAVCQSP 3539
Score = 124 bits (311), Expect = 2e-27
Identities = 323/1571 (20%), Positives = 522/1571 (33%), Gaps = 340/1571 (21%)
Query: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPT---CDALCGGDVRGPSGTILSPG 1042
F+ GS VSF C G+ L+ + C + W+ P P C + G+ P
Sbjct: 2102 FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWN-PSPMSIQCIPVRCGE---------PPS 2151
Query: 1043 YPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLP 1102
Y + N ++ V + F + + T S P P
Sbjct: 2152 IMNGYASGSNYSFGAMVAYSCNKGF----YIKGEKKSTCEATGQWSSPIPTCHPVSCGEP 2207
Query: 1103 PTINAGLYGN-----FRAQLRFISDFSISYEGFNITFSEYNLE------------PCEDP 1145
P + G + F +++R+ + G + + N C P
Sbjct: 2208 PKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKP 2267
Query: 1146 GIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPL-PRCV-AECGA 1203
Q G G NF +G + F C+ GY L G S C G+ W+ P+C+ A+C
Sbjct: 2268 PPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGK--WNKKSNPKCMPAKC-- 2323
Query: 1204 SATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKT 1263
P PL N + + + G + S + H+ QG +
Sbjct: 2324 -----------PEPPLL--ENQLVLKELTTEVGV-VTFSCKEGHVLQGPSV--------- 2360
Query: 1264 THLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFG 1323
L +Q W ++ F + ++ C P + FG
Sbjct: 2361 ----------------LKCLPSQQW----------NDSFPVC----KIVLCTPPPLISFG 2390
Query: 1324 YKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESS 1383
I GST+ Y C G+ L G+S C W PLP C+ + + +
Sbjct: 2391 VPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDG--TWSSPLPECVPVECPQPEEIPN 2448
Query: 1384 GRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLK 1443
G I G + C E+ GN +L E H W G ++
Sbjct: 2449 GIIDVQGLAYLSTALYTCKPGFEL-VGNTTTLC-----GENGH-----WLGGKPTCKAIE 2497
Query: 1444 EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV----------------ATA 1487
+ I G S ++ Q T Y GF ++ S++ A
Sbjct: 2498 CLKPKEILNGKFSYTDLHYGQTVT--YSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIH 2555
Query: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA- 1546
C P NG G G +++ C PG+++ G TC + W S P C+
Sbjct: 2556 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG----WSSSIPTCMPI 2611
Query: 1547 PCG----------GNLTGSSGFILSPN--------FPHPYPHSRDC--DWTITVNADYVI 1586
CG L G+ + PHP H W T +
Sbjct: 2612 DCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATH 2671
Query: 1587 SLAF-----ISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSD 1641
S F +S++ P Y+ L +P+ L + D
Sbjct: 2672 SSNFLYGTMVSYTCNPGYELL--------GNPV---------------------LICQED 2702
Query: 1642 GSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTC 1701
G+ + + + + C P NG + +GS V Y C G++L G C
Sbjct: 2703 GTWNGSA-----PSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLC 2757
Query: 1702 IMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVV 1760
+ W+ A P C A C + G++ NY ++ + C +V+
Sbjct: 2758 LENRK----WSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYEC------DPGYVL 2807
Query: 1761 FG--QFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPI 1818
G + D E P SS S +G G+ Q I +T
Sbjct: 2808 NGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTF----QKEIEYTCNEGF 2863
Query: 1819 TAKGFHFVY--------QAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYIL 1870
+G A P +C++ P+ G G ++ V F C+ GYIL
Sbjct: 2864 LLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYIL 2923
Query: 1871 HGSIAIRCETVPNSLAQWNDSLPTC-IVPCG-----------GILTKRKGTI---LSPGY 1915
HG+ + C++ N W+ +P C V CG G G I PGY
Sbjct: 2924 HGAPKLTCQSDGN----WDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGY 2979
Query: 1916 PEPYDNNLNCV----WKITVPE--GAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSY 1969
+++ C+ W + P V+ + T + D +D G A R+ +
Sbjct: 2980 KLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTD----FDCG--KAARIQCF 3033
Query: 1970 SGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYM 2029
G + L T ++D S+ H E+T+ G P P++ I +
Sbjct: 3034 KGFKLLGLSEITC-------EADGQWSSGFPHCEHTSCG----SLPMIPNAFISETSSWK 3082
Query: 2030 VGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMSDFSGVILSPGFP 2088
+V+++ C GY +QG S + C V W+ P P+C CG S + V + G
Sbjct: 3083 -ENVITYSCRSGYVIQGSSDLICTEKGV--WSQPYPVCEPLSCGSPPSVANAV--ATGEA 3137
Query: 2089 GNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR-SGSSETSTVIGRLSGPQIP 2147
Y S + + G+ + F+ + + R S S + + ++ +
Sbjct: 3138 HTYESEV----KLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVH 3193
Query: 2148 SSLFSTTHETSLYFHSDYSQNKQGFHIVY-----------QAYQLQSCPDPRPFRNGFVI 2196
FS + S+ Y+ + ++ SC P +GFV+
Sbjct: 3194 GDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVV 3253
Query: 2197 GNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC-EALCGGNITAMNG--- 2252
G+ +T TI ++C PGY L GN C +R W+ + C E C + +NG
Sbjct: 3254 GSKYTFESTIIYQCEPGYELEGNRERVCQE--NRQWSGGVAICKETRCETPLEFLNGKAD 3311
Query: 2253 ---------TIYS--PGYPDEYPNFQDC----FWLVRVP--PGNGIYINFTVLQTEPIYD 2295
+YS GY E P+ C W VP N + F +
Sbjct: 3312 IENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVI-------- 3363
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRV- 2354
P+ S E + + IK F G +++ + +
Sbjct: 3364 ------------PENALLS-----EKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQ 3406
Query: 2355 ---------CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQM 2405
C PP V NA + ++ GD+I Y C G+ L G C
Sbjct: 3407 TSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT- 3463
Query: 2406 DGAPPVCQVLC 2416
+PP+C+ +C
Sbjct: 3464 --SPPICRAVC 3472
Score = 107 bits (268), Expect = 2e-22
Identities = 296/1393 (21%), Positives = 465/1393 (33%), Gaps = 236/1393 (16%)
Query: 957 KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 1016
KI +S+ + L +P H R D GS V+ CD G++L C W
Sbjct: 1620 KIDSKSIFCSDCPRLGGSVP-HLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQW 1678
Query: 1017 SHPLPTCDAL-CGGDVRGPSGTILSPGY---PEFYPNSLNCTWTVDVTHGKGVQFNFHTF 1072
+ PLP C+ + CG V P L G+ +FY S VT+ Q N +
Sbjct: 1679 TQPLPHCERISCG--VPPP----LENGFHSADDFYAGS-------TVTY----QCNNGYY 1721
Query: 1073 HLEDHHDYLLITENGSFTQPLAR-------LTGSDLPPTINAGLYGNFRAQLRFISDFSI 1125
L D + T+NGS+ GSD + +I
Sbjct: 1722 LLGDSR--MFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC-----LNVDGSYICSCVP 1774
Query: 1126 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1185
Y G +E C+ PG P+ G G + +G +TFSC GY+L G ++I CL
Sbjct: 1775 PYTGDGKNCAE--PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1832
Query: 1186 GRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISAR 1244
G W+ +P C A CG A G + + + + C + K + A
Sbjct: 1833 GE--WNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1890
Query: 1245 TFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQ-----LWLEFNSDTEGTD 1299
+ V + G + + GLT ST++ L+ S E T
Sbjct: 1891 SSWSHSPPVCEPVKCSSPENINNGKYI---LSGLTYLSTASYSCDTGYSLQGPSIIECTA 1947
Query: 1300 EG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMT 1357
G + + L C +P P + +F +T+ Y C GYTL G ++C+
Sbjct: 1948 SGIWDRAPPACHLVFCGEP--PAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLA 2005
Query: 1358 GERRAWDYPLPSCIA--------------ECGGRFKGESSGRILSPGYPFPYDNNLRCMW 1403
+ W C+A E R G+ + S GY ++ L C
Sbjct: 2006 DGK--WSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNA 2063
Query: 1404 MIEVDPGNIVSL-----QFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIP----EGI 1454
+ P + F S+ IL E+ K +GS++ EG
Sbjct: 2064 QGKWVPPEGQDMPRCIAHFCEKPPSVSYSIL-------ESVSKAKFAAGSVVSFKCMEGF 2116
Query: 1455 HSTLNI-VTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQ 1513
LN I+ + S +IQ + C +P MNG +G G V +
Sbjct: 2117 --VLNTSAKIECMRGGQWNPSPMSIQ---CIPVRCGEPPSIMNGYASGSNYSFGAMVAYS 2171
Query: 1514 CDPGYELQGEERITCIQVENRYFWQPSPPVC-IAPCGGNLTGSSGFILSPNFPHPYPHSR 1572
C+ G+ ++GE++ TC E W P C CG +GF+ H
Sbjct: 2172 CNKGFYIKGEKKSTC---EATGQWSSPIPTCHPVSCGEPPKVENGFL-----EHTTGRIF 2223
Query: 1573 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLP-------- 1624
+ + N Y S+ F + N + S SPL+ D P
Sbjct: 2224 ESEVRYQCNPGYK-SVGSPVFVCQANRHW-------HSESPLMCVPLDCGKPPPIQNGFM 2275
Query: 1625 --ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK---------LRESCFDPGNIMNGTRL 1673
E E S V + + + K + C +P + N L
Sbjct: 2276 KGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVL 2335
Query: 1674 GMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1733
VT+ C G+VLQG S L C+ WN + P C +
Sbjct: 2336 KELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQ----WNDSFPVC-------------KI 2378
Query: 1734 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV-------FFQTSLHDVVEVYDGPTQQSS 1786
+ P S G + +P + FG V FF + DG T S
Sbjct: 2379 VLCTPPPLISFG------VPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDG-TWSSP 2431
Query: 1787 LLSSLS-GSHSGESLPLSSGNQITIRFTSVGPITAK-GFHFVYQAV-------------P 1831
L + E +P + + + S T K GF V P
Sbjct: 2432 LPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKP 2491
Query: 1832 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRC-ETVPNSLAQWND 1890
+ +C E G+ + G +V + CN G+ L G A+ C ET W+
Sbjct: 2492 TCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLET-----GDWDV 2546
Query: 1891 SLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1949
P+C + C + G+ E D + + + G + + E
Sbjct: 2547 DAPSCNAIHCD------SPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG 2600
Query: 1950 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNL-----YLNFQSDIS-----VSAAG 1999
W S + P PH+ L Y + D+
Sbjct: 2601 WSS---------SIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPP 2651
Query: 2000 FHLEYTAIGLDSCPE-PQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVR 2058
+HL A ++ E P T SS ++ G +VS+ C+ GY L G+ + C
Sbjct: 2652 YHLGAVAKTWENTKESPATHSS------NFLYGTMVSYTCNPGYELLGNPVLICQEDGT- 2704
Query: 2059 RWNYPIPICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS 2117
WN P C++ +C + +G + C ++ G + L N
Sbjct: 2705 -WNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCK-PGHILAGSDLRLCLENRK 2762
Query: 2118 TETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD-----------YS 2166
E S + G + G + T+ ++LY+ D
Sbjct: 2763 WSGASPRCEAISCKKPNPVMNGSIKGS-------NYTYLSTLYYECDPGYVLNGTERRTC 2815
Query: 2167 QNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH 2226
Q+ + + C P NG V G+++T + I + C G+ L G + CL
Sbjct: 2816 QDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCL- 2874
Query: 2227 GVSRNWNHPLPRC 2239
+ +W+ P C
Sbjct: 2875 -ANGSWSGATPDC 2886
Score = 105 bits (261), Expect = 1e-21
Identities = 253/1208 (20%), Positives = 414/1208 (34%), Gaps = 286/1208 (23%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWS-DHRPVCK 504
C P +NG G +F +GS VQF C+E Y L G S TCQ+ + W+ P C
Sbjct: 2264 CGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGK----WNKKSNPKCM 2319
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
C P P + Q+ +E E+G T +
Sbjct: 2320 PAKC-------------PEPPLLEN------------------QLVLKELTTEVGVVTFS 2348
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
+G VL G P ++ + SQ W ++ + C
Sbjct: 2349 CKEG----------HVLQG---PSVLKCLPSQQW--------------NDSFPVCKIVLC 2381
Query: 625 GDPGTPLYGIR-EGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI-FPCL 682
P +G+ +++ C GF L G + +CQ + WS+ +P C+ C
Sbjct: 2382 TPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECP 2441
Query: 683 SNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD- 741
P G + +G ++T PG F+L L ++G
Sbjct: 2442 QPEEIPNGII----DVQGLAYLSTALYT--CKPG---------FELVGNTTTLCGENGHW 2486
Query: 742 -------------SPESPILGTFTGAEVPSHLT---SNSHILRLEFQADHSMSGRG-FNI 784
P+ + G F+ ++ T S + RLE + + G +++
Sbjct: 2487 LGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDV 2546
Query: 785 TYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMW 844
+ C P N G ++ G+ I C GF + G TC + W
Sbjct: 2547 DAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGF-QVAGHAMQTC----EESGW 2601
Query: 845 SGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTEL 904
S IP C ++C + G K+ ++ E
Sbjct: 2602 SSSIPTC-------------------------MPIDCGLPPHIDFGDCTKLKDDQGYFEQ 2636
Query: 905 NYDVLEV----HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHY 960
D++EV P L + ++ T+ S SNF+Y T + N G+++
Sbjct: 2637 EDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHS-SNFLY--GTMVSYTCNPGYELLG 2693
Query: 961 ESVTV---------NTYSCLD-----PGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEE 1006
V + + SC+ P P +G + S+GS V +SC G+ L+ +
Sbjct: 2694 NPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSD 2753
Query: 1007 PLLCEKNHWWSHPLPTCDAL--------CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVD 1058
LC +N WS P C+A+ G ++G + T LS Y E P + ++
Sbjct: 2754 LRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPG-----YVLN 2808
Query: 1059 VTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPP-TINAGLYGN---FR 1114
T + Q + +N +P+ PP + N + G+ F+
Sbjct: 2809 GTERRTCQDD----------------KNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQ 2852
Query: 1115 AQLRFISDFSISYEGFNITFSEYNLE-----------PCEDPGIPQYGSRIGFNFGIGDT 1163
++ + + EG N C P G G ++G
Sbjct: 2853 KEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKE 2912
Query: 1164 LTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPNYPLNYE 1222
+TF C GY L G ++ C G W A +P C CG L+ +P +
Sbjct: 2913 VTFHCHEGYILHGAPKLTCQSDGN--WDAEIPLCKPVNCGPPED------LAHGFPNGFS 2964
Query: 1223 NNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSS 1282
H IQ Q G K++ + G+++G+S L
Sbjct: 2965 FIHG--GHIQYQCFPG---------------YKLHGNSSRRCLSNGSWSGSSPSCLPCRC 3007
Query: 1283 TSNQLWLEFNSDTEGTD------------EGFQLV-----------YTSFELSHCED--- 1316
++ +E+ + GTD +GF+L+ S HCE
Sbjct: 3008 STPV--IEYGT-VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 3064
Query: 1317 ---PGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1373
P IP IS+ + + I Y C GY + GSS L C E+ W P P C
Sbjct: 3065 GSLPMIP--NAFISETSSWKENVITYSCRSGYVIQGSSDLICT--EKGVWSQPYPVCEPL 3120
Query: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCM--WMIEVDPGNIVSLQFLAFDTEASHDILRV 1431
G ++ + + + LRC+ + ++ D + + E R+
Sbjct: 3121 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPE------RI 3174
Query: 1432 WDGP-----PENDMLL----------KEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGF 1476
P PEN + +++S S +NI Q D + + F
Sbjct: 3175 SCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW---EPPF 3231
Query: 1477 AIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF 1536
+ + S V +C P P +G G T+++QC+PGYEL+G C ENR
Sbjct: 3232 SDESCSPV--SCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC--QENRQ- 3286
Query: 1537 WQPSPPVC 1544
W +C
Sbjct: 3287 WSGGVAIC 3294
Score = 89.7 bits (221), Expect = 5e-17
Identities = 73/289 (25%), Positives = 117/289 (40%), Gaps = 41/289 (14%)
Query: 2685 CDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFT 2744
C+ GY+G G EC + +++ E I SC +P P + + GST+
Sbjct: 307 CEKGYYGKG-LQYECTACPSGTYKPEGSPGGISSC--IPCPDENHT----SPPGSTS--- 356
Query: 2745 CDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGE--NYGYRDTVVYQ 2802
+C+ + S C HC + NG I N + +
Sbjct: 357 -----------PEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 405
Query: 2803 CNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR--TSGNGFNFNDVVTFS 2860
C+PGF L+GSS+ +C + WSG C +C H P +G S + +
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 465
Query: 2861 CNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPAN--------SKRESKIEHGN 2912
C+ GY ++G K CQ N QW P P C +CS +P + K+ +K
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAK----- 520
Query: 2913 FTYGTVVFYDCNPGYFLFG-SSVLICQPNGQWDKPLPECIMIDCGHPGV 2960
+GT+ + C G+ L G +L C +G+W+ + + D P +
Sbjct: 521 --FGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQI 567
Score = 85.5 bits (210), Expect = 9e-16
Identities = 234/1067 (21%), Positives = 373/1067 (34%), Gaps = 201/1067 (18%)
Query: 396 ERTKELAVVTHRVKKAIDFKSRG-FKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPEN 454
E T E+ VVT K+ + K P + ++ F + LC P
Sbjct: 2337 ELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK-------IVLCTPPPLISF 2389
Query: 455 GKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ 513
G I S GSTV++SC + L+G + CQ WS P C C +
Sbjct: 2390 GVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQ----PDGTWSSPLPECVPVECPQPEE 2445
Query: 514 GPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGE-VG 572
P+G ++ TA+ T K F+L +G T G+ G +G
Sbjct: 2446 IPNGIIDVQGL----------AYLSTALYTCK------PGFEL-VGNTTTLCGENGHWLG 2488
Query: 573 DPRTV--------LQVLTGSF-VPDL----IVSMSSQMWLHLQTDESVGSV---GFKVNY 616
T ++L G F DL V+ S L+ ++ + + V+
Sbjct: 2489 GKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDA 2548
Query: 617 KEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPI 676
C P G EG +S ++ + C GF++ G C+E+ WS++IP
Sbjct: 2549 PSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPT 2607
Query: 677 CIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLA 736
C+ P+ L P G L + + + +A
Sbjct: 2608 CM---------PIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVA 2658
Query: 737 VKDGDSPESPIL--GTFTGAEVPSHLTSNSHILR----LEFQADHSMSGRGFNITYNTFG 790
++ ESP F + S+ + + L L Q D + +G +
Sbjct: 2659 KTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCI----- 2713
Query: 791 HNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPK 850
EC P P N +GS++ C+ G I G++ C+ WSG P+
Sbjct: 2714 SIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHI-LAGSDLRLCL---ENRKWSGASPR 2769
Query: 851 CGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFER-FQTELNYDV 908
C A C +G I + Y +L E +PG+ + T R Q + N+D
Sbjct: 2770 CEAISCKKPNPVMNGSIKGSNYT--YLSTL----YYECDPGYVLNGTERRTCQDDKNWDE 2823
Query: 909 LEVHDGP-NLLSPLLGSYNGTQVPQFLFSSSNFIYLL---FTTDNSRSN----NGFKIHY 960
E P + SP + + + ++ F Y F + +RS NG +
Sbjct: 2824 DEPICIPVDCSSPPVSANGQVRGDEYTF-QKEIEYTCNEGFLLEGARSRVCLANG---SW 2879
Query: 961 ESVTVN--TYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSH 1018
T + C P +G G D+ V+F C GY L L C+ + W
Sbjct: 2880 SGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDA 2939
Query: 1019 PLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFN-FHTFHLEDH 1077
+P C + G L+ G+P + HG +Q+ F + L +
Sbjct: 2940 EIPLCKPVNCGPPED-----LAHGFPNGF----------SFIHGGHIQYQCFPGYKLHGN 2984
Query: 1078 HDYLLITENGSFTQPLARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSIS------ 1126
++ NGS++ + S LP P I G +DF
Sbjct: 2985 SSRRCLS-NGSWSGS----SPSCLPCRCSTPVIEYGTVNG--------TDFDCGKAARIQ 3031
Query: 1127 -YEGFNIT-FSEYNLEP----------CED------PGIPQYGSRIGFNFGIGDT----- 1163
++GF + SE E CE P IP N I +T
Sbjct: 3032 CFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIP--------NAFISETSSWKE 3083
Query: 1164 --LTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPNYPLN 1220
+T+SC SGY ++G+S++IC G VWS P P C CG+ + + +
Sbjct: 3084 NVITYSCRSGYVIQGSSDLICTEKG--VWSQPYPVCEPLSCGSPPSVANAVATGEAHTYE 3141
Query: 1221 YENNHECI--YSIQVQAG------------KGINISARTFHLAQGDVLKIYDGKDKTTH- 1265
E C+ Y++ + I+ S + L + + G D + +
Sbjct: 3142 SEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNR 3201
Query: 1266 --LLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFG 1323
+ G + G+ +S L+ + +DE V C P P+ G
Sbjct: 3202 QVSVSCAEGYTFEGVNISVCQ----LDGTWEPPFSDESCSPV-------SCGKPESPEHG 3250
Query: 1324 YKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
+ + + F STIIY C PGY L G+ C E R W + C
Sbjct: 3251 FVVGSKYTFE-STIIYQCEPGYELEGNRERVCQ--ENRQWSGGVAIC 3294
Score = 78.6 bits (192), Expect = 1e-13
Identities = 139/641 (21%), Positives = 224/641 (34%), Gaps = 119/641 (18%)
Query: 802 NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC--------GA 853
N D+F GS+++ C G+ G + C W+G+ P C G+
Sbjct: 1698 NGFHSADDFYAGSTVTYQCNNGYYLL-GDSRMFCT---DNGSWNGVSPSCLDVDECAVGS 1753
Query: 854 PCGGHFSAPS--GVILSPGWPGYYKDSLNCEWVIEAE-PGHSIKITFERFQTELNYDVLE 910
C H S + G + P Y D NC I+ + PG+ E + E
Sbjct: 1754 DCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNP----------ENGHSSGE 1803
Query: 911 VHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 970
++ T + FS L+ T + +G H SC
Sbjct: 1804 IY---------------TVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC-KAVSC 1847
Query: 971 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL-CGG 1029
P IP +G F+ GS V++ C+ GY L+ ++ C N WSH P C+ + C
Sbjct: 1848 GKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSS 1907
Query: 1030 DVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1089
+G + G +T+ ++ T + + T +G +
Sbjct: 1908 PENINNGKYILSG----------------LTYLSTASYSCDTGYSLQGPSIIECTASGIW 1951
Query: 1090 TQ--PLARLTGSDLPPTI-NAGLYGN---FRAQLRFISDFSISYEGFNI----------- 1132
+ P L PP I +A + GN FR + + + G +
Sbjct: 1952 DRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSR 2011
Query: 1133 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1192
+ + C++P I + S + GD + CS GY L S+++C G+ W
Sbjct: 2012 SDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGK--WVP 2069
Query: 1193 P----LPRCVAE-CGASATNNEGILLS-----------------PNYPLNYENNHECIYS 1230
P +PRC+A C + + IL S + LN EC+
Sbjct: 2070 PEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRG 2129
Query: 1231 IQVQAGKGINISARTFHLAQGDVLKIYDG-KDKTTHLLGAFTGASM-RGLTLSSTSNQLW 1288
Q +S + + G+ I +G + + GA S +G +
Sbjct: 2130 GQWNPSP---MSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKG------ 2180
Query: 1289 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1348
E S E T + + T +S C +P + G+ G S + Y CNPGY
Sbjct: 2181 -EKKSTCEATGQWSSPIPTCHPVS-CGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSV 2238
Query: 1349 GSSLLKCMTGERRAWDYPLPSCIAECG-------GRFKGES 1382
GS + C + PL +CG G KGE+
Sbjct: 2239 GSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2279
Score = 78.2 bits (191), Expect = 1e-13
Identities = 251/1237 (20%), Positives = 406/1237 (32%), Gaps = 316/1237 (25%)
Query: 623 SCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
SCG+P G E G +R++C G++ +G VCQ N W + P+
Sbjct: 2203 SCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPL----- 2257
Query: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDG 740
P+ P G+ N + GS++ N+ ++L + K G
Sbjct: 2258 ---MCVPLDCGKPPPIQNGFMKGEN------FEVGSKVQFFCNEGYELVGDSSWTCQKSG 2308
Query: 741 -------------DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSG-------- 779
PE P+L V LT+ ++ + H + G
Sbjct: 2309 KWNKKSNPKCMPAKCPEPPLL---ENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLP 2365
Query: 780 -RGFNITYNTFGHNECPDP-----GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETI 833
+ +N ++ C P G+PI + GS++ C GF +G T
Sbjct: 2366 SQQWNDSFPVCKIVLCTPPPLISFGVPIPS----SALHFGSTVKYSCVGGFF-LRGNSTT 2420
Query: 834 TCILMDGKVMWSGLIPKC-GAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 892
C DG WS +P+C C P+G+I G Y +L +PG
Sbjct: 2421 LC-QPDG--TWSSPLPECVPVECPQPEEIPNGIIDVQGL-AYLSTAL-----YTCKPG-- 2469
Query: 893 IKITFERFQTELNYDVLEVHDGPNL-LSPLLGSYNGTQVPQFLFSSSNFIYLLF-TTDNS 950
F+ N L +G L P + + + L ++ L + T
Sbjct: 2470 -------FELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTY 2522
Query: 951 RSNNGFKIH--------------YESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSC 996
N GF++ ++ + N C P +G G D+S G+ + +SC
Sbjct: 2523 SCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSC 2582
Query: 997 DSGYRLSHEEPLLCEKNHWWSHPLPTCDAL-CG-------GD---VRGPSG--------- 1036
G++++ CE++ WS +PTC + CG GD ++ G
Sbjct: 2583 FPGFQVAGHAMQTCEES-GWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMM 2641
Query: 1037 --TILSPGYPEFYPNSLNCTW----------TVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1084
++P +P ++ ++ TW + + +G V + + + + L+
Sbjct: 2642 EVPYVTP-HPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQ 2700
Query: 1085 ENGSF--TQPLARLTGSDLPPTINAGL-------------YGNFRAQLRFISDFSISYEG 1129
E+G++ + P DLP G Y + SD + E
Sbjct: 2701 EDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLEN 2760
Query: 1130 FNITFSEYNLE--PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGR 1187
+ + E C+ P GS G N+ TL + C GY L GT C
Sbjct: 2761 RKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDD-- 2818
Query: 1188 RVWSAPLPRCV-AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF 1246
+ W P C+ +C + + G + Y E + C
Sbjct: 2819 KNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTC------------------- 2859
Query: 1247 HLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTL-SSTSNQLWLEFNSDTEGTDEGFQLV 1305
+G +L+ + + G+++GA+ + + +T QL N TEG D GF
Sbjct: 2860 --NEGFLLE--GARSRVCLANGSWSGATPDCVPVRCATPPQL---ANGVTEGLDYGFMKE 2912
Query: 1306 YTSFELSHCEDPGIPQFGYKISDQ-------------------------------GHFAG 1334
T HC + I K++ Q G
Sbjct: 2913 VT----FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHG 2968
Query: 1335 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFP 1394
I Y C PGY LHG+S +C++ +W PSC+ C R +P +
Sbjct: 2969 GHIQYQCFPGYKLHGNSSRRCLS--NGSWSGSSPSCL-PC----------RCSTPVIEYG 3015
Query: 1395 YDNNLRCMWMIEVDPGNIVSLQ-FLAFDTEASHDILRVWDGPPENDM---------LLKE 1444
N + D G +Q F F +I DG + L
Sbjct: 3016 TVNG------TDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3069
Query: 1445 ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV----------------ATAC 1488
I + I E N++T Y +SG+ IQ SS + +C
Sbjct: 3070 IPNAFISETSSWKENVIT-------YSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3122
Query: 1489 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQP---SPPVCI 1545
P N G+ V +C GY + + Q + R+F + SP C
Sbjct: 3123 GSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCP 3182
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
P N H H D +VN +S A Y +
Sbjct: 3183 LP--------------ENITHILVHGDD----FSVNRQVSVSCA-----------EGYTF 3213
Query: 1606 DGPD-SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1664
+G + S L G+++ P ES S SC P
Sbjct: 3214 EGVNISVCQLDGTWEP---PFSDESCSPV--------------------------SCGKP 3244
Query: 1665 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTC 1701
+ +G +G Y ST+ Y C+ GY L+G C
Sbjct: 3245 ESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3281
Score = 74.7 bits (182), Expect = 2e-12
Identities = 107/435 (24%), Positives = 159/435 (36%), Gaps = 83/435 (19%)
Query: 1844 PRFG------RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1897
PR G R + GS V C+PG+ L G+ C + QW LP C
Sbjct: 1632 PRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCL----NQGQWTQPLPHC-- 1685
Query: 1898 PCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYD 1957
+S G P P +N + G+ + Q + +Y
Sbjct: 1686 -----------ERISCGVPPPLENGFHSADDFYA--GSTVTYQCNN----------GYYL 1722
Query: 1958 GGDNN--APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLE----------YT 2005
GD+ GS++G + P L+ + SD S A+ +++ YT
Sbjct: 1723 LGDSRMFCTDNGSWNGVS-PSCLDVDECAV----GSDCSEHASCLNVDGSYICSCVPPYT 1777
Query: 2006 AIGLD-----SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 2060
G + C P P +G G+ Y VG V+F C +GY L G + ITC+ W
Sbjct: 1778 GDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES--GEW 1835
Query: 2061 NYPIPICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE 2119
N+ IP C A CG +G I F + C L G N S
Sbjct: 1836 NHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTL-AGDKESSCLANSSWS 1894
Query: 2120 TIHDYLE-VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY-- 2176
E V+ S E +G I S L T+ ++ + D + QG I+
Sbjct: 1895 HSPPVCEPVKCSSPENIN-----NGKYILSGL---TYLSTASYSCDTGYSLQGPSIIECT 1946
Query: 2177 ---------QAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHG 2227
A L C +P ++ + GN+FT T+++ C GYTL G + CL
Sbjct: 1947 ASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECL-- 2004
Query: 2228 VSRNWNHPLPRCEAL 2242
W+ +C A+
Sbjct: 2005 ADGKWSRSDQQCLAV 2019
Score = 74.3 bits (181), Expect = 2e-12
Identities = 66/251 (26%), Positives = 95/251 (37%), Gaps = 30/251 (11%)
Query: 3064 GRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGP---SVRQCTANGT 3120
G Q EC A G ++ +G+ S C + S P S C
Sbjct: 315 GLQYECTACPSGT---------YKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREG 365
Query: 3121 WSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS--YMCQPGYTMELNGSRIRTCTIN 3178
+ + C ++ C P NG + N + C PG+ +L GS I C N
Sbjct: 366 YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGF--DLVGSSIILCLPN 423
Query: 3179 GTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYI--CSPGYELSFPAVLTCVGN 3236
G WSG CR TCP Q +G + + + + + + C GY L LTC GN
Sbjct: 424 GLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGN 483
Query: 3237 GTWSGEVPQCLPKFCGDPGIPAQ--------GKREGKSFIYQSEVSFSCNFPFILVGSST 3288
W G P+C+ + C +P GK+ K + + SC FIL G
Sbjct: 484 SQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAK---FGTICYVSCRQGFILSGVKE 540
Query: 3289 RI-CQADGTWS 3298
+ C G W+
Sbjct: 541 MLRCTTSGKWN 551
Score = 74.3 bits (181), Expect = 2e-12
Identities = 49/157 (31%), Positives = 65/157 (41%), Gaps = 10/157 (6%)
Query: 2973 FGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG--SRQES 3030
F + C L+G S C NG WSGS+ +C TC P HG S
Sbjct: 398 FNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCR---VRTCPHLRQPKHGHISCSTR 454
Query: 3031 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGN----PGTTANGKVF 3086
K+T ACD GY L GS++ TC N W G +P C C +
Sbjct: 455 EMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNC 514
Query: 3087 RIDGTTFSSSVIYSCMEGYILSG-PSVRQCTANGTWS 3122
F + SC +G+ILSG + +CT +G W+
Sbjct: 515 GKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 73.6 bits (179), Expect = 3e-12
Identities = 68/245 (27%), Positives = 97/245 (39%), Gaps = 36/245 (14%)
Query: 2825 GQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHP 2884
G + SC+P + SP G TS D V C GY G T
Sbjct: 335 GGISSCIPCPDENHTSPP-GSTSPE-----DCV---CREGYRASGQT------------- 372
Query: 2885 PPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWD 2944
C++V+C P N + +F V C+PG+ L GSS+++C PNG W
Sbjct: 373 ---CELVHCPALKPPENGYFIQNTCNNHFNAACGV--RCHPGFDLVGSSIILCLPNGLWS 427
Query: 2945 KPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWS 3002
C + C H P + +S + + +T +C L G TCQ N W
Sbjct: 428 GSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWD 487
Query: 3003 GSQPHCSGDATGTCGDPG----TPGHGSRQESNFRTKSTVRYACDTGYILHGSEER-TCL 3057
G +P C T P +P + +Q + F T V +C G+IL G +E C
Sbjct: 488 GPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYV--SCRQGFILSGVKEMLRCT 545
Query: 3058 ANGSW 3062
+G W
Sbjct: 546 TSGKW 550
Score = 73.6 bits (179), Expect = 3e-12
Identities = 101/450 (22%), Positives = 169/450 (37%), Gaps = 67/450 (14%)
Query: 620 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 679
E C PG P G G+ ++ + F CQ G++L+G I C E+ +W+ IP C
Sbjct: 1785 EPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1844
Query: 680 PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVK 738
P PE CI + GS++ N + L + +
Sbjct: 1845 VSCGK----------PAIPEN-----GCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLA 1889
Query: 739 DGDSPESPILGTFTGAEVPSHLTSNSHILR-------LEFQADHSMSGRGFNITYNTFGH 791
+ SP + P ++ + +IL + D S +G +I T
Sbjct: 1890 NSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASG 1949
Query: 792 NE-----------CPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDG 840
C +P +A G+NF ++++ C+EG+ G +TI C L DG
Sbjct: 1950 IWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLA-GLDTIEC-LADG 2007
Query: 841 KVMWSGLIPKCGA------PCGGHFSAPSGVILSPGWPGYY---------KDSLNC---- 881
K WS +C A P H S + L YY L C
Sbjct: 2008 K--WSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQG 2065
Query: 882 EWVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNF 940
+WV E + F ++Y +LE + + S+ + F+ ++S
Sbjct: 2066 KWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCME--GFVLNTSAK 2123
Query: 941 IYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGY 1000
I + N + + + V C +P ++G G ++S G+ V++SC+ G+
Sbjct: 2124 IECM----RGGQWNPSPMSIQCIPVR---CGEPPSIMNGYASGSNYSFGAMVAYSCNKGF 2176
Query: 1001 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD 1030
+ E+ CE WS P+PTC + G+
Sbjct: 2177 YIKGEKKSTCEATGQWSSPIPTCHPVSCGE 2206
Score = 71.2 bits (173), Expect = 2e-11
Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 12/195 (6%)
Query: 2816 ICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFN--FNDVVTFSCNIGYLMQGPTKA 2873
+C++ + SGQ +C V C P G N N FN C+ G+ + G +
Sbjct: 361 VCREGYRASGQ--TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 2874 QCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSS 2933
C N WS C+V C P + Y T C+ GY L GS
Sbjct: 419 LCLPNGLWSGSESYCRVRTC--PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSD 476
Query: 2934 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLS-----GEKYTFGSTVHYSCTGKRSLL 2988
L CQ N QWD P P C+ C +P + ++S + FG+ + SC L
Sbjct: 477 KLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILS 536
Query: 2989 G-QSSRTCQLNGHWS 3002
G + C +G W+
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 70.1 bits (170), Expect = 4e-11
Identities = 51/200 (25%), Positives = 82/200 (41%), Gaps = 15/200 (7%)
Query: 3187 TCRAVTCPTPPQISNGR-LEGT-NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVP 3244
TC V CP NG ++ T N + + C PG++L +++ C+ NG WSG
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 431
Query: 3245 QCLPKFCGDPGIPAQG--KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSP 3302
C + C P G + +Y++ +C+ + L GS CQ + W G P
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 491
Query: 3303 HCIEPTQTSCENPG---VPRHGSQNNTFGFQVGSVVQFHCKKGHLLQG-STTRTCLPDLT 3358
C+E ++ + P + H F G++ C++G +L G C
Sbjct: 492 RCVERHCSTFQMPKDVIISPHNCGKQPAKF--GTICYVSCRQGFILSGVKEMLRCTTSGK 549
Query: 3359 WS-GIQPECIPHSCKQPETP 3377
W+ G+Q CK E P
Sbjct: 550 WNVGVQAAV----CKDVEAP 565
Score = 70.1 bits (170), Expect = 4e-11
Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 20/195 (10%)
Query: 3277 CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVV 3335
C+ F LVGSS +C +G WSGS +C T C + P+HG + +T +
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRT---CPHLRQPKHGHISCSTREMLYKTTC 462
Query: 3336 QFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANV----VGMDLPSHG 3391
C +G+ L+GS TC + W G +P C+ C + P + G G
Sbjct: 463 LVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFG 522
Query: 3392 YTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVP 3451
+C+ GF L+G E C + W V + KD +P+++ P
Sbjct: 523 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGV------QAAVCKD------VEAPQINCP 570
Query: 3452 DDVFAQNYIWKGSYN 3466
D+ A+ + S N
Sbjct: 571 KDIEAKTLEQQDSAN 585
Score = 65.5 bits (158), Expect = 9e-10
Identities = 68/272 (25%), Positives = 106/272 (38%), Gaps = 49/272 (18%)
Query: 969 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALC 1027
SC P P HG G ++ ST+ + C+ GY L +C++N WS + C + C
Sbjct: 3240 SCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRC 3299
Query: 1028 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1087
+ EF + + T G V ++ + + + TENG
Sbjct: 3300 ETPL-------------EFLNGKADIE---NRTTGPNVVYSCNRGYSLEGPSEAHCTENG 3343
Query: 1088 SFTQPLARLTGSDLPPTI----NAGLYGNFRAQLRFISDFSISY---EGFNI-------- 1132
+++ P+ + P NA L ++ F D ++S EGF +
Sbjct: 3344 TWSHPVPLCKPNPCPVPFVIPENALL-----SEKEFYVDQNVSIKCREGFLLQGHGIITC 3398
Query: 1133 --------TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1184
T ++ C P + G ++ GD +T+SC SGY LEG +CL
Sbjct: 3399 NPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLE 3458
Query: 1185 GGRRVWSAPLPRCVAECGASATNNEGILLSPN 1216
G W++P P C A C N GI PN
Sbjct: 3459 NG--TWTSP-PICRAVCRFPCQNG-GICQRPN 3486
Score = 58.5 bits (140), Expect = 1e-07
Identities = 75/307 (24%), Positives = 110/307 (35%), Gaps = 43/307 (14%)
Query: 2995 CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGS-EE 3053
C+ + G Q C+ +GT G+PG S S + + GS
Sbjct: 307 CEKGYYGKGLQYECTACPSGTYKPEGSPGGIS---------SCIPCPDENHTSPPGSTSP 357
Query: 3054 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT---FSSSVIYSCMEGYILSGP 3110
C+ + C+ V C NG + I T F+++ C G+ L G
Sbjct: 358 EDCVCREGYRASGQTCELVHCPALKPPENG--YFIQNTCNNHFNAACGVRCHPGFDLVGS 415
Query: 3111 SVRQCTANGTWSGTLPNCTIISCGDPGIPANG--------LRYGDDYVVGQNVSYMCQPG 3162
S+ C NG WSG+ C + +C P +G + Y +V C G
Sbjct: 416 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA------CDEG 469
Query: 3163 YTMELNGSRIRTCTINGTWSGVMPTCRAVTCPT---PPQI----SNGRLEGTNFDWGFSI 3215
Y +E GS TC N W G P C C T P + N + F +I
Sbjct: 470 YRLE--GSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFG---TI 524
Query: 3216 SYI-CSPGYELS-FPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEV 3273
Y+ C G+ LS +L C +G W+ V + K P I E K+ Q
Sbjct: 525 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSA 584
Query: 3274 SFSCNFP 3280
+ + P
Sbjct: 585 NVTWQIP 591
Score = 58.2 bits (139), Expect = 2e-07
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C PG PENG G +++G+ V FSC E Y L G ITC E W+ P CK
Sbjct: 1789 CKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGE----WNHLIPYCKA 1844
Query: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQC 534
+CG +G F F +C
Sbjct: 1845 VSCGKPAIPENGCIEELAFTFGSKVTYRC 1873
Score = 57.4 bits (137), Expect = 3e-07
Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 27/208 (12%)
Query: 2569 VCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGIL--TTDYLVGTRVTYFCNDGYRLSS 2626
VCR+ GY A C+ + C K P NG + T + C+ G+ L
Sbjct: 361 VCRE---GYRASGQ---TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVG 414
Query: 2627 KELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYE--YKTKVVFS 2684
+ +C +G WS C V TCP + +HG ++ S E YKT + +
Sbjct: 415 SSII--LCLPNGLWSGSESY--CRVRTCPHLRQ--PKHGH---ISCSTREMLYKTTCLVA 465
Query: 2685 CDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPP----NGNKIGTQ-TSYGS 2739
CD GY G + C G W P C C P + + G Q +G+
Sbjct: 466 CDEGYRLEGSDKLTC--QGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGT 523
Query: 2740 TAIFTCDLGFMLVG-SAVRECLSSGLWS 2766
+C GF+L G + C +SG W+
Sbjct: 524 ICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 57.0 bits (136), Expect = 3e-07
Identities = 94/421 (22%), Positives = 147/421 (34%), Gaps = 52/421 (12%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P NGK I S + ST +SCD Y LQG I C W P C +
Sbjct: 1905 CSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC----TASGIWDRAPPACHL 1960
Query: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCV--WVITAVNTNKVIQ----INFEEFDLEIG 559
CG T NF F+ C + + ++T + + ++ L +
Sbjct: 1961 VFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVS 2020
Query: 560 YDTLTIGDGGEVGDPRTVLQVLTGSFVPD-LIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
D I D + + + D ++ +SQ+ + Q + V G +
Sbjct: 2021 CDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQ-GKWVPPEG--QDMPR 2077
Query: 619 IEKESCGDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 675
C P + Y I E F+ V+ F+C GF L I C QW+ + P
Sbjct: 2078 CIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-P 2136
Query: 676 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDF 734
+ I C+ P+ P GY + N + G+ + S N F ++ +
Sbjct: 2137 MSI-QCI-----PVRCGEPPSIMNGYASGSNYSF------GAMVAYSCNKGFYIKGEKKS 2184
Query: 735 LAVKDGD-SPESPILGTFTGAEVP-------SHLTSNSHILRLEFQADHSMSGRG---FN 783
G S P + E P H T + +Q + G F
Sbjct: 2185 TCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFV 2244
Query: 784 ITYNTFGHNECPDPGIPI---------NARRFGDNFQLGSSISVICEEGFIKTQGTETIT 834
N H+E P +P+ N G+NF++GS + C EG+ + G + T
Sbjct: 2245 CQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGY-ELVGDSSWT 2303
Query: 835 C 835
C
Sbjct: 2304 C 2304
Score = 57.0 bits (136), Expect = 3e-07
Identities = 58/255 (22%), Positives = 94/255 (36%), Gaps = 38/255 (14%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P PE+G +GS ++ ST+ + C+ Y L+G + CQ + WS +CK
Sbjct: 3241 CGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ----WSGGVAICKE 3296
Query: 506 KTCGSNLQGPSG------TFTSPN--------FPFQYDSNAQCVWVITAVNTNKVIQINF 551
C + L+ +G T PN + + S A C T + + + N
Sbjct: 3297 TRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNP 3356
Query: 552 EEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP--DLIVSMSSQMWLHLQTDESVGS 609
I + L + + D ++ G + +I + W
Sbjct: 3357 CPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSA------ 3409
Query: 610 VGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ 669
+ EK SCG P I G + D++ + C G+ L G VC EN
Sbjct: 3410 --------KCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGT 3461
Query: 670 WSAN---IPICIFPC 681
W++ +C FPC
Sbjct: 3462 WTSPPICRAVCRFPC 3476
Score = 52.0 bits (123), Expect = 1e-05
Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
SCG P +P G + F G K+ Y C GY L G + +C+ANS SW P+C
Sbjct: 1846 SCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANS----SWSHSPPVC 1900
Score = 51.2 bits (121), Expect = 2e-05
Identities = 43/139 (30%), Positives = 55/139 (39%), Gaps = 17/139 (12%)
Query: 2529 CSTPESPPHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
C P HG+I T L + ACD G+RL G C+ G WD P P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQ----GNSQWDGPEPRC 493
Query: 2588 QAISCG---IPK----APTNGGILTTDYLVGTRVTYFCNDGYRLSS-KELTTAVCQSDGT 2639
C +PK +P N G + GT C G+ LS KE+ C + G
Sbjct: 494 VERHCSTFQMPKDVIISPHNCGKQPAKF--GTICYVSCRQGFILSGVKEMLR--CTTSGK 549
Query: 2640 WSNHNKTPRCVVVTCPSIN 2658
W+ + C V P IN
Sbjct: 550 WNVGVQAAVCKDVEAPQIN 568
Score = 48.9 bits (115), Expect = 9e-05
Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
SCG P + G + GD I YSC +GY+L+G + C+ N +W P PICR
Sbjct: 3415 SCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLEN----GTWTSP-PICR 3469
Query: 197 A 197
A
Sbjct: 3470 A 3470
Score = 47.4 bits (111), Expect = 3e-04
Identities = 54/251 (21%), Positives = 82/251 (32%), Gaps = 59/251 (23%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC-K 504
C P ENG DF GSTV + C+ Y L G + C +W+ P C
Sbjct: 1690 CGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD----NGSWNGVSPSCLD 1745
Query: 505 VKTCG--------SNLQGPSGTFTSPNFPFQYDSNAQCVWVI---------TAVNTNKVI 547
V C ++ G++ P C I ++ ++
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIY 1805
Query: 548 QINFE-EFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDES 606
+ E F + GY + + I + S W HL
Sbjct: 1806 TVGAEVTFSCQEGYQLMGV----------------------TKITCLESGEWNHL----- 1838
Query: 607 VGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQE 666
+ Y + SCG P P G E F+ + + C G+ L G+K C
Sbjct: 1839 -------IPY--CKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLA 1889
Query: 667 NNQWSANIPIC 677
N+ WS + P+C
Sbjct: 1890 NSSWSHSPPVC 1900
Score = 45.8 bits (107), Expect = 8e-04
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)
Query: 3325 NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANV-V 3383
NT + C G L GS+ CLP+ WSG + C +C P H ++
Sbjct: 392 NTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISC 451
Query: 3384 GMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
+ T + C G+ L G++ C+ ++ W G P C
Sbjct: 452 STREMLYKTTCLVACDEGYRLE-GSDKLTCQGNSQWDGPEPRC 493
Score = 45.1 bits (105), Expect = 0.001
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
C PG P G G + VG ++ +SC GY L G ++TC+ + W+ +P C+A
Sbjct: 1789 CKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCL----ESGEWNHLIPYCKA 1844
Query: 198 EDACGGTMRGSSGIISSPSF 217
+CG +G I +F
Sbjct: 1845 V-SCGKPAIPENGCIEELAF 1863
Score = 45.1 bits (105), Expect = 0.001
Identities = 97/424 (22%), Positives = 157/424 (37%), Gaps = 50/424 (11%)
Query: 453 ENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL 512
E G G+DF G + C + + L G ITC E WS P C+ +CGS
Sbjct: 3013 EYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITC----EADGQWSSGFPHCEHTSCGSLP 3068
Query: 513 QGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGY--DTLTIGDGGE 570
P+ + + + N + + + VIQ + + E G + +
Sbjct: 3069 MIPNAFISETS---SWKENV----ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3121
Query: 571 VGDPRTVLQ-VLTG-SFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPG 628
G P +V V TG + + V + + TD + + E+ SC
Sbjct: 3122 CGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFP-ERISCSPKK 3180
Query: 629 TPL-----YGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 683
PL + + GD FS + C G+ G VCQ + W P
Sbjct: 3181 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEP-------PFSD 3233
Query: 684 NFTAPM--GTVLSPDYPEGYGNNLNCIWTII--SDPGSRIHLSFNDFDLESQ--FDFLAV 737
+P+ G SP++ G+ TII +PG + + E++ +A+
Sbjct: 3234 ESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAI 3293
Query: 738 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYN-TFGH---- 791
E+P+ A++ + T + + +S+ G + T N T+ H
Sbjct: 3294 CKETRCETPLEFLNGKADIENRTTGPNVVYSCN--RGYSLEGPSEAHCTENGTWSHPVPL 3351
Query: 792 ---NECPDPG-IPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 847
N CP P IP NA F + ++S+ C EGF+ QG ITC + W+
Sbjct: 3352 CKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFL-LQGHGIITC---NPDETWTQT 3407
Query: 848 IPKC 851
KC
Sbjct: 3408 SAKC 3411
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
C P GV G + ++ + C GYIL G P+LTC ++ +WD +P+C+
Sbjct: 2891 CATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSD----GNWDAEIPLCKP 2946
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADC 227
+ CG + G + SF + H C
Sbjct: 2947 VN-CGPPEDLAHGFPNGFSFIHGGHIQYQC 2975
Score = 43.5 bits (101), Expect = 0.004
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
CG P G G+ + G + YSC G+ + G + TC A T W P+P C
Sbjct: 2146 CGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEA----TGQWSSPIPTCHP 2201
Query: 198 EDACGGTMRGSSGII 212
+CG + +G +
Sbjct: 2202 V-SCGEPPKVENGFL 2215
Score = 42.7 bits (99), Expect = 0.007
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P PENG F+ GS V + C++ Y L G K +C ++WS PVC+
Sbjct: 1847 CGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCL----ANSSWSHSPPVCEP 1902
Query: 506 KTCGS 510
C S
Sbjct: 1903 VKCSS 1907
Score = 42.0 bits (97), Expect = 0.011
Identities = 17/59 (28%), Positives = 28/59 (47%)
Query: 620 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 678
E+ SCG P G D F + ++C G+ L+G+ + C +N W+ P C+
Sbjct: 1686 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCL 1744
Score = 41.6 bits (96), Expect = 0.015
Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 1163 TLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPN 1216
T +C GYRLEG+ ++ C G + W P PRCV ++ + +++SP+
Sbjct: 461 TCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 40.8 bits (94), Expect = 0.025
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 4/66 (6%)
Query: 131 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
E SCG P P G + G+++ I Y C GY L+G+ + C N W
Sbjct: 3234 ESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQEN----RQWSG 3289
Query: 191 PVPICR 196
V IC+
Sbjct: 3290 GVAICK 3295
Score = 39.3 bits (90), Expect = 0.073
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 2199 DFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CG 2244
D G ++ C PG+ L+GN CL+ W PLP CE + CG
Sbjct: 1647 DLKPGSKVNLFCDPGFQLVGNPVQYCLN--QGQWTQPLPHCERISCG 1691
Score = 38.9 bits (89), Expect = 0.095
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 4/99 (4%)
Query: 2011 SCPEPQTPSSG-IKIGDRYMVGDVVSF-QCDQGYSLQGHSHITCMPGPVRRWNYPIPICL 2068
+CP + P G I R M+ CD+GY L+G +TC +W+ P P C+
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGN--SQWDGPEPRCV 494
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF 2107
+ VI+SP G P+ ++ GF
Sbjct: 495 ERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGF 533
Score = 38.9 bits (89), Expect = 0.095
Identities = 18/52 (34%), Positives = 24/52 (46%)
Query: 990 STVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSP 1041
+T +CD GYRL + L C+ N W P P C + P I+SP
Sbjct: 460 TTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 38.9 bits (89), Expect = 0.095
Identities = 16/46 (34%), Positives = 22/46 (47%)
Query: 650 CQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSP 695
C G+ L G + CQ N+QW P C+ S F P ++SP
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 38.9 bits (89), Expect = 0.095
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 10/81 (12%)
Query: 135 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
S C P P G L T +G ++YSC G+IL G C+ N W P
Sbjct: 2714 SIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLEN----RKWSGASPR 2769
Query: 195 CRA------EDACGGTMRGSS 209
C A G+++GS+
Sbjct: 2770 CEAISCKKPNPVMNGSIKGSN 2790
Score = 38.9 bits (89), Expect = 0.095
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
Query: 111 FSLRLTSDFAVSAHG-FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYI 169
F L S+ A G + + + +SCG+ + P + T + I YSC +GY+
Sbjct: 3036 FKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYV 3095
Query: 170 LDGHPQLTCIANSVNTASWDFPVPIC 195
+ G L C V W P P+C
Sbjct: 3096 IQGSSDLICTEKGV----WSQPYPVC 3117
Score = 38.5 bits (88), Expect = 0.12
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 4/58 (6%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
C +P V G + G + +I Y+C G++L+G C+AN SW P C
Sbjct: 2833 CSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLAN----GSWSGATPDC 2886
Score = 38.1 bits (87), Expect = 0.16
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 8/57 (14%)
Query: 145 PKGVLYG----TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
PK +L G T G + YSC G+ L+G LTC+ T WD P C A
Sbjct: 2501 PKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCL----ETGDWDVDAPSCNA 2553
Score = 37.4 bits (85), Expect = 0.28
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 2169 KQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFT--VGQTISFECFPGYTLIGNSALTCL 2225
++G+ Q +L CP +P NG+ I N C PG+ L+G+S + CL
Sbjct: 363 REGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCL 421
Score = 37.4 bits (85), Expect = 0.28
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 446 CPDPGEPENGKRIGS--DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
CP +P++G S + +T +CDE Y L+G+ +TCQ ++ W P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQ----WDGPEPRC 493
Query: 504 KVKTCGSNLQGPSGTFTSPN 523
+ C S Q P SP+
Sbjct: 494 VERHC-STFQMPKDVIISPH 512
Score = 37.0 bits (84), Expect = 0.36
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTC 178
CG P G + G F+VG K+++ C GY L G TC
Sbjct: 2264 CGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTC 2304
Score = 37.0 bits (84), Expect = 0.36
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 10/80 (12%)
Query: 134 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 193
++ SC P G + G+ + + Y C GY+L+G + TC + +WD P
Sbjct: 2771 EAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTC----QDDKNWDEDEP 2826
Query: 194 ICRAED------ACGGTMRG 207
IC D + G +RG
Sbjct: 2827 ICIPVDCSSPPVSANGQVRG 2846
Score = 36.2 bits (82), Expect = 0.61
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 6/65 (9%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
C +P G + G + G I YSC G+ + GH TC + W +P C
Sbjct: 2556 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTC-----EESGWSSSIPTCMP 2610
Query: 198 EDACG 202
D CG
Sbjct: 2611 ID-CG 2614
Score = 35.4 bits (80), Expect = 1.0
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Query: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSP 869
V C+EG+ + +G++ +TC G W G P+C F P VI+SP
Sbjct: 464 VACDEGY-RLEGSDKLTC---QGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 35.4 bits (80), Expect = 1.0
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 4/65 (6%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
SCG P G F G + Y C GY L G ++ C N SW+ P C
Sbjct: 1689 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDN----GSWNGVSPSCL 1744
Query: 197 AEDAC 201
D C
Sbjct: 1745 DVDEC 1749
Score = 35.4 bits (80), Expect = 1.0
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 157 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
G + YSC GY L+G + C N +W PVP+C+
Sbjct: 3318 GPNVVYSCNRGYSLEGPSEAHCTEN----GTWSHPVPLCK 3353
Score = 35.0 bits (79), Expect = 1.4
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 4/59 (6%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
+CG P G G F G I+Y C GY L G+ C++N SW P C
Sbjct: 2948 NCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSN----GSWSGSSPSC 3002
Score = 35.0 bits (79), Expect = 1.4
Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 6/79 (7%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
C P V G + GT FD G R C G+ L G ++TC A+ W P C
Sbjct: 3007 CSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEAD----GQWSSGFPHCE- 3060
Query: 198 EDACGGTMRGSSGIISSPS 216
+CG + IS S
Sbjct: 3061 HTSCGSLPMIPNAFISETS 3079
Score = 34.7 bits (78), Expect = 1.8
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Query: 1300 EGFQLVYTSFELSHCEDPGIPQFGYKISD--QGHFAGSTIIYGCNPGYTLHGSSLLKCM 1356
EG++ + EL HC P+ GY I + HF + + C+PG+ L GSS++ C+
Sbjct: 364 EGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR-CHPGFDLVGSSIILCL 421
Score = 33.9 bits (76), Expect = 3.0
Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 15/105 (14%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGD-KIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
SCG P G L T + + ++RY C GY G P C AN W P+
Sbjct: 2203 SCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQAN----RHWHSESPLM 2258
Query: 196 RAEDACG-------GTMRGSSGIISS--PSFPNE-YHNNADCTWT 230
CG G M+G + + S F NE Y D +WT
Sbjct: 2259 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWT 2303
Score = 33.5 bits (75), Expect = 4.0
Identities = 14/44 (31%), Positives = 21/44 (47%)
Query: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 181
CG P V+ G F + + Y+C GY L G + C+A+
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLAD 2006
Score = 33.1 bits (74), Expect = 5.2
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
Query: 444 NLCPDPGE-PENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
N CP P PEN +F + V C E ++LQG ITC W+
Sbjct: 3355 NPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITC----NPDETWTQTSAK 3410
Query: 503 CKVKTCG 509
C+ +CG
Sbjct: 3411 CEKISCG 3417
Score = 32.7 bits (73), Expect = 6.8
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 1335 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCI 1371
+T + C+ GY L GS L C + WD P P C+
Sbjct: 460 TTCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCV 494
Score = 32.3 bits (72), Expect = 8.9
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
Query: 163 SCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSP 215
+C GY L+G +LTC NS WD P P C E C T + +I SP
Sbjct: 465 ACDEGYRLEGSDKLTCQGNS----QWDGPEPRC-VERHC-STFQMPKDVIISP 511
Score = 32.3 bits (72), Expect = 8.9
Identities = 26/104 (25%), Positives = 35/104 (33%), Gaps = 5/104 (4%)
Query: 162 YSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEY 221
YSC TGY L G + C A+ + WD P C CG +I+ +F
Sbjct: 1929 YSCDTGYSLQGPSIIECTASGI----WDRAPPACHLV-FCGEPPAIKDAVITGNNFTFRN 1983
Query: 222 HNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTI 265
C DTI + L + EPP +
Sbjct: 1984 TVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIV 2027
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 410 bits (1053), Expect = e-113
Identities = 485/1932 (25%), Positives = 724/1932 (37%), Gaps = 356/1932 (18%)
Query: 1658 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
Query: 1717 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1771
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1826
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
Query: 1827 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1876
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
Query: 1877 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1935
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
Query: 1936 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 1995
++ S+ +SL + S + V
Sbjct: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
Query: 1996 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 2046
F CP P +G G + + G V++ CD + L G
Sbjct: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
Query: 2047 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2104
S I C P W+ P P C G++ P
Sbjct: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
Query: 2105 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2164
H F T+T + T + P+ FS T +L + S
Sbjct: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
Query: 2165 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2223
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
Query: 2224 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2281
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
Query: 2282 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2328
F ++ IY D + +W GP P + + S++S +
Sbjct: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
Query: 2329 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2378
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
Query: 2379 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2438
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
Query: 2439 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2497
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
Query: 2498 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2552
+ +C +P P+G TG L V
Sbjct: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKTV 896
Query: 2553 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2597
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
Query: 2598 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI 2657
TN +D+ +GT + Y C Y +T C + WS+ C +C +
Sbjct: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
Query: 2658 NSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS-WRNERPYCQI 2716
+ +G ++ + + +++ +SC G+ +G +S EC+ +G + W + P CQ
Sbjct: 1008 PDPV--NGMVHVI--TDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 1063
Query: 2717 ISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRECLSS----G 2763
I CG PT NG+ I T YGS + C+ G F LVG C S+ G
Sbjct: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 1123
Query: 2764 LWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIGSSVRICQQD 2820
+WS +C+ + P + NG ++ +N + + V ++C PGF + G CQ
Sbjct: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 2821 HNWSGQLPSCVPVSCGHPGSPIYG-RTSGNGFNFN--DVVTFSCNIGYLMQGPTKAQCQA 2877
+ W +LPSC V C P ++ RT + NF+ V +SC GY ++G +C
Sbjct: 1184 NKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTP 1242
Query: 2878 NRQWSHPPPMCKVVNCSD-PGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2936
WS P C+V +C D G N + + N G V + C+ G+ L GSS
Sbjct: 1243 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPV---NLQLGAKVDFVCDEGFQLKGSSASY 1299
Query: 2937 CQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCT------GK 2984
C G W+ +P C I C P V PN +G E + FG V+Y+C
Sbjct: 1300 CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTS 1359
Query: 2985 RSLLGQSSRTC----QLNGHWSGSQPHCSGDATGTCGDPGTPGH-------GSRQESNFR 3033
L+G+S+ C Q NG WS P C G G P H S+F
Sbjct: 1360 FDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFP 1414
Query: 3034 TKSTVRYACDTGYILHGSE-ERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT 3092
++++Y C Y +G TCL N W+ + CK C P NG V I
Sbjct: 1415 IGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQ 1472
Query: 3093 FSSSVIYSCMEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPANG---LRYG 3146
S + YSC G+ L G S +C +G WS P C I CG P ANG
Sbjct: 1473 VGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNR 1532
Query: 3147 DDYVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCRAVTCPTPPQ 3198
+++ G V+Y C G EL G CT N G WSG P C TPP
Sbjct: 1533 ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPN 1592
Query: 3199 ISNGRLEGTN---FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPG 3255
+ NG L N F + + C PG+ + P + C W E+P C + C P
Sbjct: 1593 VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-SRVCQPPP 1651
Query: 3256 IPAQGKR---EGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSC 3312
G+ +F EV +SC + L G+++ C G WS +P C SC
Sbjct: 1652 EILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC---AVKSC 1708
Query: 3313 EN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTWSGIQPECIP 3368
++ G HG Q+G+ V F C +G L+GS+ C+ W+ P C
Sbjct: 1709 DDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEH 1768
Query: 3369 HSCKQPE---TPAHANVVGMDLPSHGYTLIYTCQP------GFFLAGGTEHRVCRSD--- 3416
C P H D+P +G + YTC P F L G + R C SD
Sbjct: 1769 IFCPNPPAILNGRHTGTPSGDIP-YGKEISYTCDPHPDRGMTFNLIGESTIR-CTSDPHG 1826
Query: 3417 -NTWTGKVPICE 3427
W+ P CE
Sbjct: 1827 NGVWSSPAPRCE 1838
Score = 338 bits (866), Expect = 8e-92
Identities = 289/974 (29%), Positives = 406/974 (41%), Gaps = 103/974 (10%)
Query: 2537 HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPK 2596
+G ++ QL + V + CD GF+L G S++ C + W++ VP C+ I C P
Sbjct: 1267 NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSSVPVCEQIFCPSPP 1325
Query: 2597 APTNG---GILTTDYLVGTRVTYFCNDGY-RLSSKEL---TTAVCQSD----GTWSNHNK 2645
NG G + G V Y C+ R +S +L +T C SD G WS+
Sbjct: 1326 VIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSS--P 1383
Query: 2646 TPRCVVVT-CPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2704
PRC ++ C + + F+ + + N S + T + + C P Y+G P SI CL N
Sbjct: 1384 APRCGILGHCQAPDHFLFAKLKTQ-TNASDFPIGTSLKYECRPEYYGR-PFSITCLDNLV 1441
Query: 2705 WSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG 2763
WS + + C+ SC P P NG + T GS ++C G L+G + EC+ SG
Sbjct: 1442 WS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSG 1499
Query: 2764 L---WSESETRCLAGHCGIPELIVNGQVIG---ENYGYRDTVVYQCNPG------FRLIG 2811
WS C CG+P I NG I EN+ Y V Y+CN G F L+G
Sbjct: 1500 NTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVG 1559
Query: 2812 SSVRICQQDHN----WSGQLPSCV-PVSCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIG 2864
C + + WSG P C+ P C P + I + + F+ N+VV F C G
Sbjct: 1560 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 1619
Query: 2865 YLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2924
++M+GP + +CQA +W P C V P I S NF+ G VFY C
Sbjct: 1620 FVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPS--HQDNFSPGQEVFYSCE 1677
Query: 2925 PGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCT 2982
PGY L G++ L C P G W P C + C +P VL G+ V + C
Sbjct: 1678 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCD 1737
Query: 2983 GKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPG---TPGHGSRQESNFRTKS 3036
L G S C L G W+ S P C C +P H +
Sbjct: 1738 EGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI---FCPNPPAILNGRHTGTPSGDIPYGK 1794
Query: 3037 TVRYACD------TGYILHGSEERTCLA----NGSWTGRQPECK-AVQCGNPGTTAN--- 3082
+ Y CD + L G C + NG W+ P C+ +V+ G+ T
Sbjct: 1795 EISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPF 1854
Query: 3083 -GKVFRIDGTTF--SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIP 3139
I+ F +S+ Y C GY S+ C N WS NC SCG P P
Sbjct: 1855 ASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSSVEDNCRRKSCGPPPEP 1913
Query: 3140 ANGL-RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTING---TWSGVMPTCRAVTCPT 3195
NG+ D G V+Y C G+ L GS TC ++G TW P C ++C
Sbjct: 1914 FNGMVHINTDTQFGSTVNYSCNEGF--RLIGSPSTTCLVSGNNVTWDKKAPICEIISCEP 1971
Query: 3196 PPQISNGRL---EGTNFDWGFSISYICSPG------YELSFPAVLTCVGN----GTWSGE 3242
PP ISNG T+F G ++Y C G +EL + C G WS
Sbjct: 1972 PPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSP 2031
Query: 3243 VPQCL-PKFCGDPGIPAQGKREG-KSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSG 3299
P+C+ C P + + G +SF +E + F C F++VGS T CQ +G W
Sbjct: 2032 PPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGP 2091
Query: 3300 SSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL 3357
PHC C+ P HG ++ F G V + C+ + L+G+ + C P
Sbjct: 2092 KLPHC----SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQG 2147
Query: 3358 TWSGIQPECIPHSCKQ--PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAG-GTEHRVCR 3414
WS P C SC + P ++ ++L G + + C GF L G H V
Sbjct: 2148 DWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNL-QLGAKVSFVCDEGFRLKGRSASHCVLA 2206
Query: 3415 SDNT-WTGKVPICE 3427
W VP+CE
Sbjct: 2207 GMKALWNSSVPVCE 2220
Score = 334 bits (856), Expect = 1e-90
Identities = 296/1001 (29%), Positives = 414/1001 (41%), Gaps = 122/1001 (12%)
Query: 2537 HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPK 2596
+G ++ QL + V + CD GF+L G S++ C + W++ VP C+ I C P
Sbjct: 817 NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSSVPVCEQIFCPSPP 875
Query: 2597 APTNG---GILTTDYLVGTRVTYFCNDGY-RLSSKEL---TTAVCQSD----GTWSNHNK 2645
NG G + G V Y C+ R +S +L +T C SD G WS+
Sbjct: 876 VIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSS--P 933
Query: 2646 TPRCVVVT-CPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2704
PRC ++ C + + F+ + + N S + T + + C P Y+G P SI CL N
Sbjct: 934 APRCGILGHCQAPDHFLFAKLKTQ-TNASDFPIGTSLKYECRPEYYGR-PFSITCLDNLV 991
Query: 2705 WSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG 2763
WS + + C+ SC P P NG + T GS ++C G L+G + EC+ SG
Sbjct: 992 WS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSG 1049
Query: 2764 L---WSESETRCLAGHCGIPELIVNGQVIG---ENYGYRDTVVYQCNPG------FRLIG 2811
WS C CG+P I NG I EN+ Y V Y+CNPG F L+G
Sbjct: 1050 NAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 1109
Query: 2812 SSVRICQQDHN----WSGQLPSCV-PVSCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIG 2864
C + + WSG P C+ P C P + I + + F+ N+VV F C G
Sbjct: 1110 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 1169
Query: 2865 YLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2924
++M+GP + +CQA +W P C V C P +++R + + NF+ G VFY C
Sbjct: 1170 FVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQR-DKDNFSPGQEVFYSCE 1227
Query: 2925 PGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCT 2982
PGY L G++ + C P G W P C + C + VL G+ V + C
Sbjct: 1228 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCD 1287
Query: 2983 GKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPGTPG--HGSRQESNFRTKST 3037
L G S+ C L G W+ S P C + P P H + F
Sbjct: 1288 EGFQLKGSSASYCVLAGMESLWNSSVPVC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKA 1345
Query: 3038 VRYACD------TGYILHGSEERTCLA----NGSWTGRQPECKAV-QCGNPG-------- 3078
V Y CD T + L G C + NG W+ P C + C P
Sbjct: 1346 VNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLK 1405
Query: 3079 TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGI 3138
T N F I +S+ Y C Y P C N WS C SC P
Sbjct: 1406 TQTNASDFPI-----GTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPD 1459
Query: 3139 PANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAVTCP 3194
P NG+ + D VG ++Y C G+ L G C ++G WS P C+ + C
Sbjct: 1460 PVNGMVHVITDIQVGSRINYSCTTGH--RLIGHSSAECILSGNTAHWSTKPPICQRIPCG 1517
Query: 3195 TPPQISNGRLEGT---NFDWGFSISYICSPG------YELSFPAVLTCVGN----GTWSG 3241
PP I+NG T NF +G ++Y C+ G +EL + C N G WSG
Sbjct: 1518 LPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSG 1577
Query: 3242 EVPQC-LPKFCGDP----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGT 3296
PQC +P C P GI R F V F C F++ G CQA
Sbjct: 1578 PAPQCIIPNKCTPPNVENGILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 1635
Query: 3297 WSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL 3354
W P C C+ P HG + ++ F G V + C+ G+ L+G+ + C
Sbjct: 1636 WEPELPSC----SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCT 1691
Query: 3355 PDLTWSGIQPECIPHSCKQ--PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR- 3411
P WS P C SC + P H V+ G + + C GF L G +
Sbjct: 1692 PQGDWSPEAPRCAVKSCDDFLGQLP-HGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHC 1750
Query: 3412 -VCRSDNTWTGKVPICEAGSKILVKDPRPAL------GTPS 3445
+ + W VP+CE I +P PA+ GTPS
Sbjct: 1751 VLVGMRSLWNNSVPVCE---HIFCPNP-PAILNGRHTGTPS 1787
Score = 321 bits (823), Expect = 7e-87
Identities = 274/992 (27%), Positives = 410/992 (41%), Gaps = 124/992 (12%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
C TP P +G + T Q+ S + ++C G RL+G SSA C S H W P CQ
Sbjct: 1454 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAH-WSTKPPICQ 1512
Query: 2589 AISCGIPKAPTNGGILTT---DYLVGTRVTYFCNDGYR-LSSKELT---TAVCQSD---- 2637
I CG+P NG ++T ++ G+ VTY CN G R EL + C S+
Sbjct: 1513 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1572
Query: 2638 GTWSNHNKTPRCVV---VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGP 2694
G WS P+C++ T P++ + IL N S + V F C PG+ GP
Sbjct: 1573 GIWS--GPAPQCIIPNKCTPPNVENGILVSD-----NRSLFSLNEVVEFRCQPGFVMKGP 1625
Query: 2695 ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDL 2747
++C W E P SC + PP G T S G ++C+
Sbjct: 1626 RRVKC--QALNKWEPELP-----SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEP 1678
Query: 2748 GFMLVGSAVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNP 2805
G+ L G+A C G WS RC C + +L + N V + C+
Sbjct: 1679 GYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDE 1738
Query: 2806 GFRLIGSSVRIC---QQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG---NGFNFNDVVTF 2859
GFRL GSSV C W+ +P C + C +P + + GR +G + +++
Sbjct: 1739 GFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISY 1798
Query: 2860 SCN------IGYLMQGPTKAQC----QANRQWSHPPPMCKVV----NCSDPGIPANSKRE 2905
+C+ + + + G + +C N WS P P C++ +C P +
Sbjct: 1799 TCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1858
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN 2963
I F GT + Y+C PGYF +F S C N W C CG P P N
Sbjct: 1859 IPINDFEFPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFN 1915
Query: 2964 AVLSGEKYT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDP 3019
++ T FGSTV+YSC L+G S TC ++G+ W P C +C P
Sbjct: 1916 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPP 1972
Query: 3020 GTPGHG---SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQ 3066
T +G S ++F + V Y C TG + L G C + G W+
Sbjct: 1973 PTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP 2032
Query: 3067 PECKAV-QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTW 3121
P C + +C P R+ G T + + + C G+++ G QC NG W
Sbjct: 2033 PRCISTNKCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 2089
Query: 3122 SGTLPNCTIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTING 3179
LP+C+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G
Sbjct: 2090 GPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQG 2147
Query: 3180 TWSGVMPTCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNG 3237
WS P C +C Q+ +GR L N G +S++C G+ L + CV G
Sbjct: 2148 DWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAG 2207
Query: 3238 ---TWSGEVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVG 3285
W+ VP C FC +P G+ G F Y E+S++C+ F L+G
Sbjct: 2208 MKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIG 2267
Query: 3286 SSTRIC----QADGTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHC 3339
S+ C Q +G WS +P C +C +P ++G + + G + + C
Sbjct: 2268 ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYIC 2327
Query: 3340 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTL 3394
G+LL G C WS + C +C P N + +L +G +
Sbjct: 2328 DPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYV 2384
Query: 3395 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
C+ G+ L G + C++D+ W + C
Sbjct: 2385 TLKCEDGYTLEGSPWSQ-CQADDRWDPPLAKC 2415
Score = 299 bits (766), Expect = 3e-80
Identities = 244/822 (29%), Positives = 336/822 (40%), Gaps = 94/822 (11%)
Query: 2679 TKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSY 2737
T + + C PGY G P SI CL N W+ +R C+ SC P P NG + +
Sbjct: 67 TYLNYECRPGYSGR-PFSIICLKNSVWTGAKDR--CRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 2738 GSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQVIG---E 2791
GS ++C G+ L+GS+ C+ SG +W C CG+P I NG I E
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 2792 NYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PVSCGHPG- 2839
N+ Y V Y+CNPG F L+G C + + WSG P C+ P C P
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 2840 -SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGI 2898
+ I + + F+ N+VV F C G++M+GP + +CQA +W P C V C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPD 302
Query: 2899 PANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH- 2957
+++R + + NF+ G VFY C PGY L G++ + C P G W P C + C
Sbjct: 303 VLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 2958 -PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDAT 3013
+ VL G+ V + C L G S+ C L G W+ S P C +
Sbjct: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC--EQI 419
Query: 3014 GTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA----NGS 3061
P P H + F TV Y CD T + L G C + NG
Sbjct: 420 FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGV 479
Query: 3062 WTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSV 3112
W+ P C + C P T N F I +S+ Y C Y P
Sbjct: 480 WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY-YGRPFS 533
Query: 3113 RQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSR 3171
C N WS C SC P P NG+ + D VG ++Y C G+ L G
Sbjct: 534 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH--RLIGHS 591
Query: 3172 IRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPG--- 3222
C ++G WS P C+ + C PP I+NG T NF +G ++Y C+PG
Sbjct: 592 SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGG 651
Query: 3223 ---YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKREGKSFIYQ 3270
+EL + C N G WSG PQC +P C P GI R F
Sbjct: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR--SLFSLN 709
Query: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFG 3328
V F C F++ G CQA W P C C+ P H +Q +
Sbjct: 710 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAERTQRDKDN 765
Query: 3329 FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHANVVGMDL 3387
F G V + C+ G+ L+G+ + C P WS P C SC + V+
Sbjct: 766 FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVN 825
Query: 3388 PSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3427
G + + C GF L G + + ++ W VP+CE
Sbjct: 826 LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
Score = 272 bits (695), Expect = 5e-72
Identities = 266/1003 (26%), Positives = 398/1003 (39%), Gaps = 129/1003 (12%)
Query: 2529 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2584
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
Query: 2585 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2642
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
Query: 2643 HNKTPRCVVVTC---PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHG------LG 2693
N+TP C + C P+I +G + N ++ Y + V + C+PG G +G
Sbjct: 156 -NETPICDRIPCGLPPTIT-----NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 209
Query: 2694 PASIECLPNG--TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLG 2748
SI C N W P C I + P NG + S S F C G
Sbjct: 210 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 269
Query: 2749 FMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNP 2805
F++ G +C + W E E + C P +++ Q +N+ V Y C P
Sbjct: 270 FVMKGPRRVKCQALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 328
Query: 2806 GFRLIGSSVRICQQDHNWSGQLPSCVPVSC-GHPGSPIYGRT-SGNGFNFNDVVTFSCNI 2863
G+ L G++ C +WS P+C SC G + GR V F C+
Sbjct: 329 GYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 388
Query: 2864 GYLMQGPTKAQC---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVF 2920
G+ ++G + + C W+ P+C+ + C P + N + K F +G V
Sbjct: 389 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGK-PLEVFPFGKTVN 447
Query: 2921 YDCNP------GYFLFGSSVLIC----QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 2970
Y C+P + L G S + C Q NG W P P C ++ GH P + + + K
Sbjct: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLK 505
Query: 2971 -------YTFGSTVHYSCTGKRSLLGQS-SRTCQLNGHWSGSQPHCSGDATGTCGDPGTP 3022
+ G+++ Y C + G+ S TC N WS + C +C P P
Sbjct: 506 TQTNASDFPIGTSLKYEC--RPEYYGRPFSITCLDNLVWSSPKDVCK---RKSCKTPPDP 560
Query: 3023 GHGS-RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPG 3078
+G ++ + S + Y+C TG+ L G C+ +G+ W+ + P C+ + CG P
Sbjct: 561 VNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPP 620
Query: 3079 TTANGKVFRIDGTTF--SSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLP 3126
T ANG + F S V Y C G + L G CT+N G WSG P
Sbjct: 621 TIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 3127 NCTIISCGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSG 3183
C I + P NG+ D+ + + + V + CQPG+ M+ G R C W
Sbjct: 681 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEP 738
Query: 3184 VMPTCRAVTCPTPPQISNG---RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
+P+C V C PP + + + + NF G + Y C PGY+L A + C G WS
Sbjct: 739 ELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
Query: 3241 GEVPQCLPKFCGDPGIPAQGKREGKSFIYQ------SEVSFSCNFPFILVGSSTRICQAD 3294
P C K C D G+ ++ ++V F C+ F L GSS C
Sbjct: 798 PAAPTCEVKSCDD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 853
Query: 3295 G---TWSGSSPHCIEPTQTSCENPGVPRHGSQNN------TFGFQVGSVVQFHCKKGHL- 3344
G W+ S P C Q C +P V +G FG V H +G
Sbjct: 854 GMESLWNSSVPVC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSF 910
Query: 3345 -LQGSTTRTCLPDL----TWSGIQPEC-IPHSCKQPETPAHANVV----GMDLPSHGYTL 3394
L G +T C D WS P C I C+ P+ A + D P G +L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-GTSL 969
Query: 3395 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
Y C+P ++ G C + W+ +C+ S DP
Sbjct: 970 KYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDP 1010
Score = 209 bits (533), Expect = 3e-53
Identities = 241/937 (25%), Positives = 355/937 (37%), Gaps = 198/937 (21%)
Query: 2355 CQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
C PP + N + + T + F G ++ Y+C G R + ++ G P
Sbjct: 1516 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLG----------SRGRKVFELVGEP---S 1562
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK--EFDV 2471
+ C +N+ D G+ P PN C +VE G ++ F + EF
Sbjct: 1563 IYCTSND---DQVGIWSGPAPQCIIPN--KCT-PPNVENGILVSDNRSLFSLNEVVEFRC 1616
Query: 2472 LQ--VYDGP--------NIQSPVLISLS-----------GDYSSAFNIT-SNGHEVFLQW 2509
V GP N P L S S G+++ + S G EVF +
Sbjct: 1617 QPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVF--Y 1674
Query: 2510 SADHGNNKKGFRIRYIAFYCS-----TPESP--------------PHGYIISQTGGQLNS 2550
S + G + +G + +C+ +PE+P PHG ++ QL +
Sbjct: 1675 SCEPGYDLRGAA----SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGA 1730
Query: 2551 VVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG---GILTTD 2607
V + CD GFRL G S + C W+ VP C+ I C P A NG G + D
Sbjct: 1731 KVSFVCDEGFRLKGSSVSHCVLVGMR-SLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGD 1789
Query: 2608 YLVGTRVTYFCND----GYRLSSKELTTAVCQSD----GTWSN------------HNKTP 2647
G ++Y C+ G + +T C SD G WS+ H KTP
Sbjct: 1790 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1849
Query: 2648 RCVVVTCPSI--NSF------------------------ILEHGRWRIV----------- 2670
P+I N F LE+ W V
Sbjct: 1850 EQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGP 1909
Query: 2671 -----NGSHY-----EYKTKVVFSCDPGYHGLGPASIECLPNGT-WSWRNERPYCQIISC 2719
NG + ++ + V +SC+ G+ +G S CL +G +W + P C+IISC
Sbjct: 1910 PPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC 1969
Query: 2720 GELPTPPNGNKIGT-QTSY--GSTAIFTCDLG------FMLVGSAVRECLSS----GLWS 2766
PT NG+ +TS+ G+ + C G F LVG C S G+WS
Sbjct: 1970 EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 2029
Query: 2767 ESETRCLAGH-CGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2823
RC++ + C PE+ +V G + + + ++C PGF ++GS CQ + W
Sbjct: 2030 SPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 2089
Query: 2824 SGQLPSCVPVSCGHPGSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
+LP C V C P ++G + + F+ V +SC Y ++G C
Sbjct: 2090 GPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD 2148
Query: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFGSSV 2934
WS P C V +C D ++ HG N G V + C+ G+ L G S
Sbjct: 2149 WSPEAPRCTVKSCDD--------FLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSA 2200
Query: 2935 LICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGEKY---TFGSTVHYSCTGKR--- 2985
C G W+ +P C I C +P N +G + +G + Y+C
Sbjct: 2201 SHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRG 2260
Query: 2986 ---SLLGQSSRTC----QLNGHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTK 3035
+L+G+SS C Q NG WS P C C P +G S +
Sbjct: 2261 MTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPG 2320
Query: 3036 STVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT--- 3092
T+ Y CD GY+L G C G W+ CK V C P NG ++
Sbjct: 2321 MTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFP-LFMNGISKELEMKKVYH 2379
Query: 3093 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3129
+ V C +GY L G QC A+ W L CT
Sbjct: 2380 YGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCT 2416
Score = 132 bits (332), Expect = 6e-30
Identities = 305/1388 (21%), Positives = 470/1388 (33%), Gaps = 279/1388 (20%)
Query: 1484 VATACRDPGVPMNGTRNGDGREP---GDTVVFQCDPGYELQGEERITCIQVENRYFWQPS 1540
+ C P V NG D R + V F+C PG+ ++G R+ C Q N+ W+P
Sbjct: 1134 IPNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC-QALNK--WEPE 1189
Query: 1541 PP----VCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIE 1596
P VC P P+ H RD D + + + +S E
Sbjct: 1190 LPSCSRVCQPP--------------PDVLHAERTQRDKD-NFSPGQE-------VFYSCE 1227
Query: 1597 PNYDFL------------YIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSD--- 1641
P YD + P F L R+ N + L + D
Sbjct: 1228 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVN-LQLGAKVDFVC 1286
Query: 1642 --------GSVSY---TGFHLEYKAKL----RESCFDPGNIMNGTRLGMD---YKLGSTV 1683
S SY G + + + + C P I NG G + G V
Sbjct: 1287 DEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAV 1346
Query: 1684 TYYCD------AGYVLQGYSTLTCIMGDDGRPGWNRALPSC------HAPCGSRSTGSEG 1731
Y CD + L G ST+ C G W+ P C AP +
Sbjct: 1347 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 1406
Query: 1732 TVLSPNYPKNYSVGHNCVYSI-AVPKEFVVFGQFVFFQTSLHDVVE---VYDGPTQQSSL 1787
+ ++P S+ + C P V+ +S DV + P + +
Sbjct: 1407 QTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVW--SSPKDVCKRKSCKTPPDPVNGM 1464
Query: 1788 LSSLSGSHSGESLPLS--SGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1845
+ ++ G + S +G+++ ++ ++ H+ + P C P
Sbjct: 1465 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKP-PICQRIPCGLPPTIA 1523
Query: 1846 FGRRIGNE---FAVGSSVLFDCNPG------YILHGSIAIRCETVPNSLAQWNDSLPTCI 1896
G I F GS V + CN G + L G +I C + + + W+ P CI
Sbjct: 1524 NGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 1583
Query: 1897 VP--C------GGILTKRKGTILS----------PGYPEPYDNNLNCV----WKITVPEG 1934
+P C GIL ++ S PG+ + C W+ +P
Sbjct: 1584 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 1643
Query: 1935 AGI-QVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDI 1993
+ + Q EH D + G YS L + S L+ Q D
Sbjct: 1644 SRVCQPPPEILHGEHTPSHQDNFSPGQEVF-----YSCEPGYDLRGAAS--LHCTPQGDW 1696
Query: 1994 SVSAAGFHLEYTAIGLDSCPE--PQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHIT 2051
S A + SC + Q P + +G VSF CD+G+ L+G S
Sbjct: 1697 SPEAP-------RCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSH 1749
Query: 2052 CMPGPVRR-WNYPIPICL-AQCGGAMSDFSGVILSPGFP-GNYPSSLDCTWTINLPIGFG 2108
C+ +R WN +P+C C + +G G P G+ P + ++T + G
Sbjct: 1750 CVLVGMRSLWNNSVPVCEHIFCPNPPAILNG--RHTGTPSGDIPYGKEISYTCDPHPDRG 1807
Query: 2109 VHLQFVNFSTETIHD---------------YLEVRSGSSETSTVIGRLSGPQIPSSLFST 2153
+ + ST L VR+G +T + P IP + F
Sbjct: 1808 MTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFP-FASPTIPINDFEF 1866
Query: 2154 THETSLYFHSDYSQNKQGFHI----------VYQAYQLQSC-PDPRPFRNGFVIGNDFTV 2202
TSL + + F I V + +SC P P PF I D
Sbjct: 1867 PVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF 1926
Query: 2203 GQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYP 2260
G T+++ C G+ LIG+ + TCL G + W+ P CE + C T NG YS
Sbjct: 1927 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1986
Query: 2261 DEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----DFITVWDGPDQNSPQIGQFSG 2315
+ + P G + F ++ IY D + VW P + +
Sbjct: 1987 SFHNGTVVTYQCHTGPDGEQL---FELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA 2043
Query: 2316 NTALESVYSTSNQI------LIKFHSDFTTSGFFVLSYHAYQL--------------RVC 2355
++ N+ +I+F GF ++ H Q RVC
Sbjct: 2044 PEVENAIRVPGNRSFFTLTEIIRFRCQ---PGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 2100
Query: 2356 QPPPPVPNAE-ILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAP--PVC 2412
QPPP + + E L+ D F G + Y C P + L G A L C Q D +P P C
Sbjct: 2101 QPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC----TPQGDWSPEAPRC 2156
Query: 2413 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDV 2471
V + L G +L P NLQ+ A S ++G+ +
Sbjct: 2157 TVKSCDDFLGQLPHGRVLLP------LNLQLGAKVSFVCDEGFRL--------------- 2195
Query: 2472 LQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCST 2531
G + VL + ++S+ + +C
Sbjct: 2196 ----KGRSASHCVLAGMKALWNSSVPVCEQ-------------------------IFCPN 2226
Query: 2532 PESPPHGYIISQTGGQL--NSVVRWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAP 2583
P + +G G + + +AC DRG F L+G+SS C G W +P
Sbjct: 2227 PPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSP 2286
Query: 2584 VPACQ---AISCGIPKAPTNG---GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSD 2637
P C+ +C P NG G + YL G ++Y C+ GY L K C
Sbjct: 2287 APRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGF--IFCTDQ 2344
Query: 2638 GTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASI 2697
G WS + + V + P + I + + V Y Y V C+ GY G
Sbjct: 2345 GIWSQLDHYCKEVNCSFPLFMNGISKELEMKKV----YHYGDYVTLKCEDGYTLEGSPWS 2400
Query: 2698 ECLPNGTW 2705
+C + W
Sbjct: 2401 QCQADDRW 2408
Score = 80.1 bits (196), Expect = 4e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 1907 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1965
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 1966 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 2000
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 2001 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 2050
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 684
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 2051 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 2098
Query: 685 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 742
P +L ++ + +N + PG + S +DL GD S
Sbjct: 2099 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 2150
Query: 743 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 802
PE+P + + L +L L
Sbjct: 2151 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 2177
Query: 803 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 2178 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 2219
Score = 72.4 bits (176), Expect = 8e-12
Identities = 225/1043 (21%), Positives = 355/1043 (34%), Gaps = 219/1043 (20%)
Query: 808 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 859
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
Query: 860 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 912
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
Query: 913 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 970
P++L + Q +F S Y L + R + T SC
Sbjct: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
Query: 971 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 1025
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
Query: 1026 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1083
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
Query: 1084 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1128
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
Query: 1129 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1169
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
Query: 1170 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1226
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
Query: 1227 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1277
+ + + G G + F L + D + I+ G + T ++
Sbjct: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
Query: 1278 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1321
L S + L+ +EF +G + V EL C P +
Sbjct: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
Query: 1322 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1380
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
Query: 1381 E-SSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDIL----RVWDGP 1435
+ +GR+L FP + L D G F + AS+ +L +W+
Sbjct: 814 QLLNGRVL-----FPVNLQLGAKVDFVCDEG------FQLKGSSASYCVLAGMESLWNSS 862
Query: 1436 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
+ S +IP G H+ + F
Sbjct: 863 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPF------------------------------ 892
Query: 1496 NGTRNGDGREPGDTVVFQCDP------GYELQGEERITCI-QVENRYFWQPSPPVCIAPC 1548
G TV + CDP ++L GE I C + W P C
Sbjct: 893 -----------GKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---- 937
Query: 1549 GGNLTGSSGFILSPN---FPHPYPHSRDCDWTITVNADYVISLAFIS--FSIEPNYDFLY 1603
G G +P+ F + D+ I + Y + FSI + ++
Sbjct: 938 -----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVW 992
Query: 1604 -----------IYDGPDSNSPLIGSFQDSKLPERIESSSNTMH-LAFRSDGSVSYTGFHL 1651
PD + ++ D ++ RI S T H L S +G
Sbjct: 993 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAA 1052
Query: 1652 EYKAK----LRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYST 1698
+ K R C P I NG + ++ GS VTY C+ G + L G +
Sbjct: 1053 HWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 1112
Query: 1699 LTCIMGDDGRPGWNRALPSCHAP 1721
+ C DD W+ P C P
Sbjct: 1113 IYCTSNDDQVGIWSGPAPQCIIP 1135
Score = 70.9 bits (172), Expect = 2e-11
Identities = 196/861 (22%), Positives = 310/861 (36%), Gaps = 172/861 (19%)
Query: 654 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 693
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 460 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 519
Query: 694 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 749
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 520 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 564
Query: 750 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 800
T +V S + + H L A+ +SG + + P G+P
Sbjct: 565 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPC-GLPPTIA 623
Query: 801 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 850
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 624 NGDFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
Query: 851 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQ 901
C P C + +G+++S + SLN +PG +K +++
Sbjct: 682 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 737
Query: 902 TELNYDVLEVHDGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 959
EL P++L + Q +F S Y L + R
Sbjct: 738 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
Query: 960 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNH 1014
+ T SC D G ++GR + + +G+ V F CD G++L C
Sbjct: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES 857
Query: 1015 WWSHPLPTCDAL-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTF 1072
W+ +P C+ + C P+G G P E +P +T D +G F+
Sbjct: 858 LWNSSVPVCEQIFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD---- 911
Query: 1073 HLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SD 1122
LI E+ + G P G+ G+ +A F+ SD
Sbjct: 912 ---------LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 962
Query: 1123 F----SISYE--------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNF 1158
F S+ YE F+IT + NL + C+ P P G + +
Sbjct: 963 FPIGTSLKYECRPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDI 1021
Query: 1159 GIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPN 1216
+G + +SC++G+RL G S C L G WS P C CG T G +S N
Sbjct: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
Query: 1217 YPLNYENNHE-CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHL 1266
EN H + + + G G + F L + D + I+ G +
Sbjct: 1082 R----ENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII 1134
Query: 1267 LGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE 1315
T ++ L S + L+ +EF +G + V EL C
Sbjct: 1135 PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCS 1194
Query: 1316 -----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPS 1369
P + D+ +F+ G + Y C PGY L G++ ++C + W P+
Sbjct: 1195 RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPT 1252
Query: 1370 CIAECGGRFKGE-SSGRILSP 1389
C + F G+ +GR+L P
Sbjct: 1253 CEVKSCDDFMGQLLNGRVLFP 1273
Score = 69.7 bits (169), Expect = 5e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 1606 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1660
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
+ +N + PG + S +DL GD SPE+P
Sbjct: 1661 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1701
Query: 758 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 817
R ++ G+ +P F N QLG+ +S
Sbjct: 1702 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1733
Query: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 868
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 1734 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1790
Query: 869 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 923
P + S C +P +TF + H SP L
Sbjct: 1791 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1841
Query: 924 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 966
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 1842 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1901
Query: 967 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 1020
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 1902 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1961
Query: 1021 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1080
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 1962 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 2008
Query: 1081 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
L+ E + G S PP R IS +
Sbjct: 2009 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 2042
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 2043 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 2097
Query: 1199 AEC 1201
C
Sbjct: 2098 RVC 2100
Score = 65.9 bits (159), Expect = 7e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 654 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 693
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 1360 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 1419
Query: 694 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 749
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 1420 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1464
Query: 750 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 800
T +V S + + H L A+ +SG + + P G+P
Sbjct: 1465 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1523
Query: 801 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 850
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 1524 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1581
Query: 851 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 908
C P C + +G+++S + SLN +PG +K LN
Sbjct: 1582 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1637
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 960
E+ + P +G P + S + ++ + G +H
Sbjct: 1638 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1697
Query: 961 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1014
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 1698 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1757
Query: 1015 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 1758 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1808
Query: 1066 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1121
FN T D H NG ++ P R S F + I+
Sbjct: 1809 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1862
Query: 1122 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1156
DF S++YE F FS LE C P P G I
Sbjct: 1863 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1922
Query: 1157 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1214
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1923 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1982
Query: 1215 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1274
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1983 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 2032
Query: 1275 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1310
R + T N + + N E GF +V + +
Sbjct: 2033 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 2092
Query: 1311 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1364
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 2093 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 2150
Query: 1365 YPLPSCIAECGGRFKGE-SSGRILSP 1389
P C + F G+ GR+L P
Sbjct: 2151 PEAPRCTVKSCDDFLGQLPHGRVLLP 2176
Score = 65.9 bits (159), Expect = 7e-10
Identities = 198/976 (20%), Positives = 330/976 (33%), Gaps = 193/976 (19%)
Query: 1334 GSTIIYGCNPGYTLHGSSLLKC-MTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1392
GS I Y C G+ L G S +C ++G W P C G ++G +S
Sbjct: 1474 GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 1533
Query: 1393 -FPYDN--NLRCMWMIEVDPGNIVSLQFLAFDT--------EASHDILRVWDGPPENDML 1441
F Y + RC N+ S F+ ++ D + +W GP ++
Sbjct: 1534 NFHYGSVVTYRC---------NLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII 1584
Query: 1442 LKEISGSLIPEGIHSTLN--IVTIQFDTDF-----YISKSGFAIQFSS---------SVA 1485
+ + + GI + N + ++ +F ++ K ++ + S +
Sbjct: 1585 PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCS 1644
Query: 1486 TACRDPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPP 1542
C+ P ++G + D PG V + C+PGY+L+G + C + W P P
Sbjct: 1645 RVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAP 1701
Query: 1543 VCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFL 1602
C + G PH R +N ++F+
Sbjct: 1702 RCAVKSCDDFLGQ------------LPHGR---VLFPLNLQLGAKVSFVC---------- 1736
Query: 1603 YIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCF 1662
D L GS S S+ + + RS + S + E F
Sbjct: 1737 ------DEGFRLKGS-----------SVSHCVLVGMRSLWNNS---------VPVCEHIF 1770
Query: 1663 DPG--NIMNGTRLGM---DYKLGSTVTYYCD------AGYVLQGYSTLTCIMGDDGRPGW 1711
P I+NG G D G ++Y CD + L G ST+ C G W
Sbjct: 1771 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVW 1830
Query: 1712 NRALPSCH--APCGSRSTGSEGTVLSPNYPKN---YSVGHNCVYSIAVPKEFVVFGQFVF 1766
+ P C G T + SP P N + VG + Y FG+ +F
Sbjct: 1831 SSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPG----YFGK-MF 1885
Query: 1767 FQTSLHDVV--EVYDG---------PTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSV 1815
+ L ++V V D P + ++ + + G ++ S + +
Sbjct: 1886 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1945
Query: 1816 GPITAKGFHFVY-QAVPRTSSTQCSSVPEPRFGRRIGN---EFAVGSSVLFDCNPG---- 1867
G + + + P C P G N F G+ V + C+ G
Sbjct: 1946 TTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGE 2005
Query: 1868 --YILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNC 1925
+ L G +I C + + + W+ P CI + + I PG + L
Sbjct: 2006 QLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFF--TLTE 2063
Query: 1926 VWKITVPEG-AGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLN-STSN 1983
+ + G + V T W + P + T+ H N S
Sbjct: 2064 IIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQ 2123
Query: 1984 NLYLNFQSDISV-SAAGFHL--------EYTAIGLDSCPE--PQTPSSGIKIGDRYMVGD 2032
++ + + + AA H E + SC + Q P + + +G
Sbjct: 2124 EVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGA 2183
Query: 2033 VVSFQCDQGYSLQGHSHITC-MPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNY 2091
VSF CD+G+ L+G S C + G WN +P+C F N
Sbjct: 2184 KVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC----------------EQIFCPNP 2227
Query: 2092 PSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLF 2151
P+ L+ T P G + + ++++ +T D T +IG SS+
Sbjct: 2228 PAILNGRHT-GTPFGDIPYGKEISYACDTHPD-------RGMTFNLIGE-------SSIR 2272
Query: 2152 STTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV---GQTISF 2208
T+ + +S + A +CP P +NG IG ++ G TIS+
Sbjct: 2273 CTSDPQG---NGVWSSPAPRCELSVPA----ACPHPPKIQNGHYIGGHVSLYLPGMTISY 2325
Query: 2209 ECFPGYTLIGNSALTC 2224
C PGY L+G + C
Sbjct: 2326 ICDPGYLLVGKGFIFC 2341
Score = 63.9 bits (154), Expect = 3e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
C G T T+ +F ++TN+ NF + + Y
Sbjct: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
Query: 625 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
Query: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 740
S P VL + + +N + PG + S +DL G
Sbjct: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 741 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 790
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 791 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 828
E CP P + N R G + F G +++ C+
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
Query: 829 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 862
G TI C G +WS P+CG GH AP
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
Score = 62.8 bits (151), Expect = 6e-09
Identities = 137/619 (22%), Positives = 201/619 (32%), Gaps = 134/619 (21%)
Query: 648 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 699
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 756
G N C DP SF D ES + G+ S +P G +
Sbjct: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
Query: 757 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 795
P H T+ S L+++ GR F+IT + C
Sbjct: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
Query: 796 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 853
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
Query: 854 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 908
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 963
+ + GP + V L S + ++ L R GF + +
Sbjct: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
Query: 964 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 1011
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 1012 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1069
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
Query: 1070 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1129
L GS + AG+ + + +
Sbjct: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
Query: 1130 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1180
C P + G G F G T+ ++C + + L G S I
Sbjct: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 918
Query: 1181 ICLGG--GRRVWSAPLPRC 1197
C G VWS+P PRC
Sbjct: 919 RCTSDPQGNGVWSSPAPRC 937
Score = 60.8 bits (146), Expect = 2e-08
Identities = 143/626 (22%), Positives = 213/626 (34%), Gaps = 125/626 (19%)
Query: 137 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
Query: 196 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 250
+ CG ++G S + N +H + T+ PG +F
Sbjct: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
Query: 251 KYDYLEIEGSEPPTIWLSGMNIPPP------IISNKNWLRLHFVTDSNHRYRGFSAPYQG 304
D + I P + PP + N++ L+ V + F
Sbjct: 668 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVE-------FRCQPGF 720
Query: 305 SSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVT----- 359
L + V P DV + T S Q V +
Sbjct: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
Query: 360 SLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFK-SRG 418
LR + T + SP A T + Q+ + L V ++ +DF G
Sbjct: 781 DLRGAASMRCTPQGDWSP-AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEG 839
Query: 419 FKLFPGKDNSNKFSILNEGGIKTASN---------LCPDPGEPENGKRIGSD---FSLGS 466
F+L K +S + +L G+++ N CP P NG+ G F G
Sbjct: 840 FQL---KGSSASYCVL--AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGK 894
Query: 467 TVQFSCD------EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 520
TV ++CD + L G +I C + WS P C + + Q P
Sbjct: 895 TVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL---GHCQAPDHFLF 951
Query: 521 SPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQV 580
+ + +NA + T++ + F ++T D P+ V +
Sbjct: 952 A---KLKTQTNASDFPIGTSLKYECRPEYYGRPF-------SITCLDNLVWSSPKDVCKR 1001
Query: 581 LTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYK----------------------- 617
+ PD + M +H+ TD VGS ++NY
Sbjct: 1002 KSCKTPPDPVNGM-----VHVITDIQVGS---RINYSCTTGHRLIGHSSAECILSGNAAH 1053
Query: 618 ------EIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIG 658
++ CG P T I GD S NR+ V+ + C G FEL+G
Sbjct: 1054 WSTKPPICQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 1109
Query: 659 EKSIVCQENNQ----WSANIPICIFP 680
E SI C N+ WS P CI P
Sbjct: 1110 EPSIYCTSNDDQVGIWSGPAPQCIIP 1135
Score = 60.8 bits (146), Expect = 2e-08
Identities = 136/619 (21%), Positives = 200/619 (32%), Gaps = 134/619 (21%)
Query: 648 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 699
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 892
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 756
G N C DP SF D ES + G+ S +P G +
Sbjct: 893 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 945
Query: 757 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 795
P H T+ S L+++ GR F+IT + C
Sbjct: 946 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 1005
Query: 796 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 853
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 1006 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 1064
Query: 854 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 908
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 1065 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 1121
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 963
+ + GP + V L S + ++ L R GF + +
Sbjct: 1122 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 1181
Query: 964 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 1011
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 1182 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 1241
Query: 1012 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1069
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 1242 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 1291
Query: 1070 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1129
L GS + AG+ + + +
Sbjct: 1292 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 1320
Query: 1130 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1180
C P + G G F G + ++C + + L G S I
Sbjct: 1321 ------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 1368
Query: 1181 ICLGG--GRRVWSAPLPRC 1197
C G VWS+P PRC
Sbjct: 1369 RCTSDPQGNGVWSSPAPRC 1387
Score = 60.5 bits (145), Expect = 3e-08
Identities = 132/647 (20%), Positives = 223/647 (34%), Gaps = 127/647 (19%)
Query: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSCIA 1372
C +P P G +G GS I Y C GY L GSS C+ +G+ WD P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1373 ECGGRFKGESSGRILSPGYP-FPYDN--NLRCMWMIEVDPGNIVSLQFL-----AFDTEA 1424
G ++G +S F Y + RC +PG+ F + +
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRC------NPGSGGRKVFELVGEPSIYCTS 217
Query: 1425 SHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN--IVTIQFDTDF-----YISKSGFA 1477
+ D + +W GP ++ + + + GI + N + ++ +F ++ K
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
Query: 1478 IQFSS---------SVATACRDPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEER 1525
++ + S + C+ P ++ R + D PG V + C+PGY+L+G
Sbjct: 278 VKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 337
Query: 1526 ITCIQVENRYFWQPSPPVCIAPCGGNLTGS--SGFILSPNFPHPYPHSRDCDWTITVNAD 1583
+ C + W P+ P C + G +G +L P
Sbjct: 338 MRCTPQGD---WSPAAPTCEVKSCDDFMGQLLNGRVLFP--------------------- 373
Query: 1584 YVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS 1643
++ + DF+ D L GS + +ES N+
Sbjct: 374 -------VNLQLGAKVDFVC-----DEGFQLKGSSASYCVLAGMESLWNS---------- 411
Query: 1644 VSYTGFHLEYKAKLRESCFDPGN--IMNGTRLGMD---YKLGSTVTYYCD------AGYV 1692
+ E F P I NG G + G TV Y CD +
Sbjct: 412 ----------SVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 1693 LQGYSTLTCIMGDDGRPGWNRALP------SCHAPCGSRSTGSEGTVLSPNYPKNYSVGH 1746
L G ST+ C G W+ P C AP + + ++P S+ +
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 1747 NC-VYSIAVPKEFVVFGQFVFFQTSLHDVVE---VYDGPTQQSSLLSSLSGSHSGESLPL 1802
C P V+ +S DV + P + ++ ++ G +
Sbjct: 522 ECRPEYYGRPFSITCLDNLVW--SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 1803 S--SGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVG 1857
S +G+++ ++ ++ H+ + P C P G I F G
Sbjct: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKP-PICQRIPCGLPPTIANGDFISTNRENFHYG 638
Query: 1858 SSVLFDCNPG------YILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1898
S V + CNPG + L G +I C + + + W+ P CI+P
Sbjct: 639 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 60.1 bits (144), Expect = 4e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 769 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 817
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
Query: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 876
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
Query: 877 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 931
S+ PG + FE N D + + GP +P N P
Sbjct: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
Query: 932 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 974
L S + ++ L R GF + + +N + C P
Sbjct: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
Query: 975 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 1031
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 1032 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1089
G +G +L +P +L VD +G Q
Sbjct: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
Query: 1090 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1149
L GS + AG+ + + + C P +
Sbjct: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
Query: 1150 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1197
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 59.7 bits (143), Expect = 5e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 1142 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1198
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1199 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1248
CG T G +S N EN H + + + G G + F L
Sbjct: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
Query: 1249 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1303
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 1304 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1351
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
Query: 1352 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1410
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
Query: 1411 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1466
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
Query: 1467 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1520
G TV + CDP ++L
Sbjct: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
Query: 1521 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1576
GE I C + W P C G G +P+ F + D+
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
Query: 1577 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1623
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
Query: 1624 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1675
RI S T H L S +G + K R C P I NG +
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
Query: 1676 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1721
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 54.7 bits (130), Expect = 2e-06
Identities = 61/257 (23%), Positives = 92/257 (35%), Gaps = 50/257 (19%)
Query: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
FS +V+ F CQ GF + G + + CQ N+W +P C S P VL + +
Sbjct: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPDVLHAERTQ 760
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
+N + PG + S +DL GD SP +P + +
Sbjct: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
Query: 758 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 794
L N +L +++F D +G + +Y E C
Sbjct: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
Query: 795 PDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQGTETITCIL-MDGKVMWS 845
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 872 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 846 GLIPKCGAPCGGHFSAP 862
P+CG GH AP
Sbjct: 932 SPAPRCGIL--GHCQAP 946
Score = 54.7 bits (130), Expect = 2e-06
Identities = 61/257 (23%), Positives = 92/257 (35%), Gaps = 50/257 (19%)
Query: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
FS +V+ F CQ GF + G + + CQ N+W +P C S P VL + +
Sbjct: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPDVLHAERTQ 1210
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
+N + PG + S +DL GD SP +P + +
Sbjct: 1211 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 1262
Query: 758 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 794
L N +L +++F D +G + +Y E C
Sbjct: 1263 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 1321
Query: 795 PDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQGTETITCIL-MDGKVMWS 845
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 1322 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 1381
Query: 846 GLIPKCGAPCGGHFSAP 862
P+CG GH AP
Sbjct: 1382 SPAPRCGIL--GHCQAP 1396
Score = 51.2 bits (121), Expect = 2e-05
Identities = 124/627 (19%), Positives = 214/627 (34%), Gaps = 127/627 (20%)
Query: 1334 GSTIIYGCNPGYTLHGSSLLKC-MTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1392
GS I Y C G+ L G S +C ++G W P C G ++G +S
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
Query: 1393 -FPYDN--NLRCMWMIEVDPGNIVSLQFL-----AFDTEASHDILRVWDGPPENDMLLKE 1444
F Y + RC +PG+ F + ++ D + +W GP ++ +
Sbjct: 634 NFHYGSVVTYRC------NPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
Query: 1445 ISGSLIPEGIHSTLN--IVTIQFDTDF-----YISKSGFAIQFSS---------SVATAC 1488
+ + GI + N + ++ +F ++ K ++ + S + C
Sbjct: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
Query: 1489 RDPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
+ P ++ R + D PG V + C+PGY+L+G + C + W P+ P C
Sbjct: 748 QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD---WSPAAPTCE 804
Query: 1546 APCGGNLTGS--SGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLY 1603
+ G +G +L P ++ + DF+
Sbjct: 805 VKSCDDFMGQLLNGRVLFP----------------------------VNLQLGAKVDFVC 836
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
D L GS + +ES N+ + E F
Sbjct: 837 -----DEGFQLKGSSASYCVLAGMESLWNS--------------------SVPVCEQIFC 871
Query: 1664 PGN--IMNGTRLGMD---YKLGSTVTYYCD------AGYVLQGYSTLTCIMGDDGRPGWN 1712
P I NG G + G TV Y CD + L G ST+ C G W+
Sbjct: 872 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 1713 RALP------SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC-VYSIAVPKEFVVFGQFV 1765
P C AP + + ++P S+ + C P V
Sbjct: 932 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV 991
Query: 1766 FFQTSLHDVVE---VYDGPTQQSSLLSSLSGSHSGESLPLS--SGNQITIRFTSVGPITA 1820
+ +S DV + P + ++ ++ G + S +G+++ ++ ++
Sbjct: 992 W--SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSG 1049
Query: 1821 KGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSSVLFDCNPG------YILH 1871
H+ + P C P G I F GS V + CNPG + L
Sbjct: 1050 NAAHWSTKP-PICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 1108
Query: 1872 GSIAIRCETVPNSLAQWNDSLPTCIVP 1898
G +I C + + + W+ P CI+P
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIP 1135
Score = 51.2 bits (121), Expect = 2e-05
Identities = 184/870 (21%), Positives = 288/870 (33%), Gaps = 206/870 (23%)
Query: 461 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 520
+ LG+ V F CDE + L+G+ + C +A + + W+ PVC+ C S P+G T
Sbjct: 1275 NLQLGAKVDFVCDEGFQLKGSSASYCV-LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHT 1333
Query: 521 SPN---FPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGD----GGEVGD 573
FPF N C FDL IG T+ G
Sbjct: 1334 GKPLEVFPFGKAVNYTC----------DPHPDRGTSFDL-IGESTIRCTSDPQGNGVWSS 1382
Query: 574 PRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY----------------- 616
P +L PD + L QT+ S +G + Y
Sbjct: 1383 PAPRCGILGHCQAPDHFLFAK----LKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLD 1438
Query: 617 -------KEI-EKESCGDPGTPLYG-IREGDGFSNRDVLRFECQFGFELIGEKSIVC--- 664
K++ +++SC P P+ G + + + C G LIG S C
Sbjct: 1439 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1498
Query: 665 QENNQWSANIPIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTII 712
WS PIC PC T G +S + Y G+ ++ ++
Sbjct: 1499 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1558
Query: 713 SDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 772
+P I+ + ND D + + G +P+ I
Sbjct: 1559 GEPS--IYCTSND-------DQVGIWSGPAPQCII------------------------- 1584
Query: 773 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQG 829
N+C P + N DN F L + C+ GF+ +G
Sbjct: 1585 ------------------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKG 1624
Query: 830 TETITCILMDGKVMWSGLIPKCGAPC--------GGH-------FSAPSGVILS--PGWP 872
+ C ++ W +P C C G H FS V S PG+
Sbjct: 1625 PRRVKCQALN---KWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYD 1681
Query: 873 GYYKDSLNC----EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPL---LGSY 925
SL+C +W EA P ++K + + F +L + +L PL LG+
Sbjct: 1682 LRGAASLHCTPQGDWSPEA-PRCAVK-SCDDFLGQLPHG--------RVLFPLNLQLGAK 1731
Query: 926 NGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYG- 983
+ F S+ + + S NN + C +P ++GR G
Sbjct: 1732 VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPV------CEHIFCPNPPAILNGRHTGT 1785
Query: 984 --HDFSIGSTVSFSCD------SGYRLSHEEPLLCEK----NHWWSHPLPTCD-ALCGGD 1030
D G +S++CD + L E + C N WS P P C+ ++ G
Sbjct: 1786 PSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGH 1845
Query: 1031 VRGPSG-TILSPGYP--EF-YPNSLNCTWTVDVTH-GKGVQFN-FHTFHLEDHHDYLLIT 1084
+ P SP P +F +P + + + GK + D
Sbjct: 1846 CKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRK 1905
Query: 1085 ENGSFTQPLARL----TGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE---- 1136
G +P + T + T+N FR L + G N+T+ +
Sbjct: 1906 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFR--LIGSPSTTCLVSGNNVTWDKKAPI 1963
Query: 1137 YNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSCSSG------YRLEGTSEIICLGGGR 1187
+ CE P G N F G +T+ C +G + L G I C
Sbjct: 1964 CEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDD 2023
Query: 1188 R--VWSAPLPRCVAECGASATNNEGILLSP 1215
+ VWS+P PRC++ +A E + P
Sbjct: 2024 QVGVWSSPPPRCISTNKCTAPEVENAIRVP 2053
Score = 49.3 bits (116), Expect = 7e-05
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
SC P P G+++ T VG +I YSC TG+ L GH CI S NTA W PIC
Sbjct: 1453 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSTKPPIC 1511
Query: 196 R 196
+
Sbjct: 1512 Q 1512
Score = 49.3 bits (116), Expect = 7e-05
Identities = 70/277 (25%), Positives = 100/277 (36%), Gaps = 34/277 (12%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 1454 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNTAHWSTKPPICQ 1512
Query: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 1513 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1566
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
G P + P+ ++VS + ++ + E GF
Sbjct: 1567 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1626
Query: 613 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 660
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 1627 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1686
Query: 661 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 695
S+ C WS P C +F P G VL P
Sbjct: 1687 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1723
Score = 48.1 bits (113), Expect = 2e-04
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 654 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 690
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 1810 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1869
Query: 691 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 743
T L+ + GY + N +W+ + D R K P
Sbjct: 1870 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1910
Query: 744 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 795
P G T + S + S + RL + G N+T++ C
Sbjct: 1911 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1970
Query: 796 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 846
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 1971 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 2030
Query: 847 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 901
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 2031 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 2090
Query: 902 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 959
+L + P +L L + Q +F S Y L +
Sbjct: 2091 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 2150
Query: 960 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1014
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 2151 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 2210
Query: 1015 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1074
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 2211 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 2257
Query: 1075 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1118
+ + LI E NG ++ P R PP I G Y L
Sbjct: 2258 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 2316
Query: 1119 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1160
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 2317 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 2374
Query: 1161 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1199
GD +T C GY LEG+ C R W PL +C +
Sbjct: 2375 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 2417
Score = 47.0 bits (110), Expect = 3e-04
Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 34/277 (12%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA-AHWSTKPPICQ 612
Query: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
G P + P+ ++VS + ++ + E GF
Sbjct: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 613 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 660
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
Query: 661 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 695
S+ C WS P C +F + G VL P
Sbjct: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
Score = 47.0 bits (110), Expect = 3e-04
Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 34/277 (12%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA-AHWSTKPPICQ 1062
Query: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 1116
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
G P + P+ ++VS + ++ + E GF
Sbjct: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
Query: 613 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 660
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 1177 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 661 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 695
S+ C WS P C +F + G VL P
Sbjct: 1237 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 1273
Score = 46.6 bits (109), Expect = 5e-04
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 131 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
Query: 190 FPVPIC 195
PIC
Sbjct: 156 NETPIC 161
Score = 46.6 bits (109), Expect = 5e-04
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 131 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 1900 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1958
Query: 190 FPVPIC 195
PIC
Sbjct: 1959 KKAPIC 1964
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 1487 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1544
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 1545 IAPCGGNLTGSSGFILSPN 1563
PCG T ++G +S N
Sbjct: 163 RIPCGLPPTITNGDFISTN 181
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 436 EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
E + + S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C +
Sbjct: 1637 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD- 1695
Query: 493 FAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 522
WS P C VK+C L Q P G P
Sbjct: 1696 ---WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1723
Score = 44.3 bits (103), Expect = 0.002
Identities = 83/385 (21%), Positives = 138/385 (35%), Gaps = 90/385 (23%)
Query: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 212
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 1866 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1919
Query: 213 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 270
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 1920 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1972
Query: 271 NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAV 330
P ISN ++ SN+R + + +T+ TG E G ++
Sbjct: 1973 ----PTISNGDFY-------SNNR-----TSFHNGTVVTYQCHTGPDGEQLFELVGERSI 2016
Query: 331 ASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHP---ADTQSTRR 387
T S++ +V V S SP P + + T
Sbjct: 2017 YCT-----------------SKDDQVGVWS---------------SPPPRCISTNKCTAP 2044
Query: 388 RPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPG--KDNSNKFSILNEGG----IKT 441
+A ++ + +T ++ F+ PG S+ G +
Sbjct: 2045 EVENAIRVPGNRSFFTLTEIIR---------FRCQPGFVMVGSHTVQCQTNGRWGPKLPH 2095
Query: 442 ASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSD 498
S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C + WS
Sbjct: 2096 CSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD----WSP 2151
Query: 499 HRPVCKVKTCGSNL-QGPSGTFTSP 522
P C VK+C L Q P G P
Sbjct: 2152 EAPRCTVKSCDDFLGQLPHGRVLLP 2176
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 436 EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
E + + S +C PD E +R +FS G V +SC+ Y L+GA S+ C +
Sbjct: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD- 345
Query: 493 FAAWSDHRPVCKVKTC 508
WS P C+VK+C
Sbjct: 346 ---WSPAAPTCEVKSC 358
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 436 EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
E + + S +C PD E +R +FS G V +SC+ Y L+GA S+ C +
Sbjct: 1187 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD- 1245
Query: 493 FAAWSDHRPVCKVKTC 508
WS P C+VK+C
Sbjct: 1246 ---WSPAAPTCEVKSC 1258
Score = 37.0 bits (84), Expect = 0.36
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 446 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 2298 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 2353
Query: 503 CKVKTC 508
CK C
Sbjct: 2354 CKEVNC 2359
Score = 36.6 bits (83), Expect = 0.47
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 19/113 (16%)
Query: 402 AVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPD--------PGEPE 453
+VVT+R + SRG K+F + + N+ + S P P E
Sbjct: 1539 SVVTYRC----NLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 1594
Query: 454 NGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
NG + + FSL V+F C +V++G + + CQ + + W P C
Sbjct: 1595 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 1643
Score = 35.0 bits (79), Expect = 1.4
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 24/105 (22%)
Query: 419 FKLFPGKDNSNKFSILNEGGIKTASN--------------LCPD---PGEPENGKRIGSD 461
++ PG F ++ E I SN + P+ P ENG + +
Sbjct: 193 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 252
Query: 462 ---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
FSL V+F C +V++G + + CQ + + W P C
Sbjct: 253 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
Score = 35.0 bits (79), Expect = 1.4
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 24/105 (22%)
Query: 419 FKLFPGKDNSNKFSILNEGGIKTASN--------------LCPD---PGEPENGKRIGSD 461
++ PG F ++ E I SN + P+ P ENG + +
Sbjct: 1093 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 1152
Query: 462 ---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
FSL V+F C +V++G + + CQ + + W P C
Sbjct: 1153 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 1193
Score = 33.9 bits (76), Expect = 3.0
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 461 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 508
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 2178 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 2224
Score = 33.5 bits (75), Expect = 4.0
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 2028 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2075
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 2378 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 2423
Score = 33.1 bits (74), Expect = 5.2
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
Query: 185 TASWDFPVPICR---AEDACGGTMRG 207
W P C +D G + G
Sbjct: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG 368
Score = 33.1 bits (74), Expect = 5.2
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
Query: 185 TASWDFPVPICR---AEDACGGTMRG 207
W P C +D G + G
Sbjct: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG 818
Score = 33.1 bits (74), Expect = 5.2
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 1187 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 1243
Query: 185 TASWDFPVPICR---AEDACGGTMRG 207
W P C +D G + G
Sbjct: 1244 -GDWSPAAPTCEVKSCDDFMGQLLNG 1268
Score = 32.7 bits (73), Expect = 6.8
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 185 TASWDFPVPICRAEDAC 201
W P P C + C
Sbjct: 672 VGIWSGPAPQCIIPNKC 688
Score = 32.7 bits (73), Expect = 6.8
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 1121
Query: 185 TASWDFPVPICRAEDAC 201
W P P C + C
Sbjct: 1122 VGIWSGPAPQCIIPNKC 1138
Score = 32.7 bits (73), Expect = 6.8
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 1512 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1571
Query: 185 TASWDFPVPICRAEDAC 201
W P P C + C
Sbjct: 1572 VGIWSGPAPQCIIPNKC 1588
Score = 32.3 bits (72), Expect = 8.9
Identities = 20/73 (27%), Positives = 25/73 (34%), Gaps = 9/73 (12%)
Query: 138 CGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVNTASW 188
CG P G T F G + Y C G + L G P + C +N W
Sbjct: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
Query: 189 DFPVPICRAEDAC 201
P P C + C
Sbjct: 226 SGPAPQCIIPNKC 238
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 399 bits (1025), Expect = e-110
Identities = 476/1934 (24%), Positives = 720/1934 (37%), Gaps = 357/1934 (18%)
Query: 1658 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
Query: 1717 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1771
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1826
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
Query: 1827 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1876
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
Query: 1877 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1935
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
Query: 1936 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 1995
++ S+ +SL + S + V
Sbjct: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
Query: 1996 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 2046
F CP P +G G + + G V++ CD + L G
Sbjct: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
Query: 2047 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2104
S I C P W+ P P C G++ P
Sbjct: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
Query: 2105 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2164
H F T+T + T + P+ FS T +L + S
Sbjct: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
Query: 2165 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2223
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
Query: 2224 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2281
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
Query: 2282 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2328
F ++ IY D + +W GP P + + S++S +
Sbjct: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
Query: 2329 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2378
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
Query: 2379 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2438
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
Query: 2439 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2497
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
Query: 2498 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2552
+ +C +P P+G TG L V
Sbjct: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKAV 896
Query: 2553 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2597
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
Query: 2598 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI 2657
TN +D+ +GT + Y C Y +T C + WS+ C +C +
Sbjct: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
Query: 2658 NSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNG-TWSWRNERPYCQI 2716
+ +G ++ + + +++ +SC G+ +G +S EC+ +G T W + P CQ
Sbjct: 1008 PDPV--NGMVHVI--TDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
Query: 2717 ISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRECLSS----G 2763
I CG PT NG+ I T YGS + C+LG F LVG C S+ G
Sbjct: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
Query: 2764 LWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIGSSVRICQQD 2820
+WS +C+ + P + NG ++ +N + + V ++C PGF + G CQ
Sbjct: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 2821 HNWSGQLPSCVPVSCGHPGSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2877
+ W +LPSC V C P ++G + + F+ V +SC GY ++G C
Sbjct: 1184 NKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 2878 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFG 2931
WS P C V +C D ++ HG N G V + C+ G+ L G
Sbjct: 1243 QGDWSPEAPRCAVKSCDD--------FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG 1294
Query: 2932 SSVLICQPNGQ---WDKPLPECIMIDCGHP---------GVPPNAVLSGEKYTFGSTVHY 2979
SSV C G W+ +P C I C +P G P + G++ ++ H
Sbjct: 1295 SSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHP 1354
Query: 2980 SCTGKRSLLGQSSRTCQL----NGHWSGSQPHCS-GDATGTCGDPGTPGHGSR----QES 3030
+L+G+S+ C NG WS P C G C P S +
Sbjct: 1355 DRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 3031 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG 3090
F +++ Y C GY +CL N W+ + C+ CG P NG V
Sbjct: 1415 EFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTD 1473
Query: 3091 TTFSSSVIYSCMEGYILSGPSVRQCTANG---TWSGTLPNCTIISCGDPGIPANGLRYGD 3147
T F S+V YSC EG+ L G C +G TW P C IISC P +NG Y +
Sbjct: 1474 TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSN 1533
Query: 3148 D---YVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCRAVTCPTP 3196
+ + G V+Y C G EL G R CT G WS P C + T
Sbjct: 1534 NRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA 1593
Query: 3197 PQISNG-RLEGTN--FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD 3253
P++ N R+ G F I + C PG+ + + C NG W ++P C + C
Sbjct: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-SRVCQP 1652
Query: 3254 PGIPAQGKR---EGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3310
P G+ +F EV +SC + L G+++ C G WS +P C T
Sbjct: 1653 PPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC---TVK 1709
Query: 3311 SCEN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTWSGIQPEC 3366
SC++ G HG Q+G+ V F C +G L+G + C+ W+ P C
Sbjct: 1710 SCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC 1769
Query: 3367 IPHSCKQPETPAHANVVGM---DLPSHGYTLIYTCQP------GFFLAGGTEHRVCRSD- 3416
C P + G D+P +G + Y C F L G + R C SD
Sbjct: 1770 EQIFCPNPPAILNGRHTGTPFGDIP-YGKEISYACDTHPDRGMTFNLIGESSIR-CTSDP 1827
Query: 3417 ---NTWTGKVPICE 3427
W+ P CE
Sbjct: 1828 QGNGVWSSPAPRCE 1841
Score = 321 bits (823), Expect = 7e-87
Identities = 274/992 (27%), Positives = 411/992 (41%), Gaps = 124/992 (12%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
C TP P +G + T Q+ S + ++C G RL+G SSA C S H W P CQ
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAH-WSTKPPICQ 1062
Query: 2589 AISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLSSK-ELT---TAVCQSD---- 2637
I CG+P NG ++T+ + G+ VTY CN G R EL + C S+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 2638 GTWSNHNKTPRCVV---VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGP 2694
G WS P+C++ T P++ + IL N S + V F C PG+ GP
Sbjct: 1123 GIWSG--PAPQCIIPNKCTPPNVENGILVSD-----NRSLFSLNEVVEFRCQPGFVMKGP 1175
Query: 2695 ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDL 2747
++C W E P SC + PP G T S G ++C+
Sbjct: 1176 RRVKC--QALNKWEPELP-----SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEP 1228
Query: 2748 GFMLVGSAVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNP 2805
G+ L G+A C G WS RC C + +L + N V + C+
Sbjct: 1229 GYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDE 1288
Query: 2806 GFRLIGSSVRICQ---QDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN---GFNFNDVVTF 2859
GFRL GSSV C W+ +P C + C +P + + GR +G + +++
Sbjct: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISY 1348
Query: 2860 SCN------IGYLMQGPTKAQCQA----NRQWSHPPPMCKVV----NCSDPGIPANSKRE 2905
+C+ + + + G + +C + N WS P P C++ +C P +
Sbjct: 1349 TCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN 2963
I F GT + Y+C PGYF +F S C N W C CG P P N
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFN 1465
Query: 2964 AVLSGEKYT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDP 3019
++ T FGSTV+YSC L+G S TC ++G+ W P C +C P
Sbjct: 1466 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPP 1522
Query: 3020 GTPGHG---SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQ 3066
T +G S ++F + V Y C TG + L G C + G W+
Sbjct: 1523 PTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP 1582
Query: 3067 PECKAV-QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTW 3121
P C + +C P R+ G T + + + C G+++ G QC NG W
Sbjct: 1583 PRCISTNKCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 1639
Query: 3122 SGTLPNCTIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTING 3179
LP+C+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G
Sbjct: 1640 GPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQG 1697
Query: 3180 TWSGVMPTCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNG 3237
WS P C +C Q+ +GR L N G +S++C G+ L + CV G
Sbjct: 1698 DWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAG 1757
Query: 3238 T---WSGEVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVG 3285
W+ VP C FC +P G+ G F Y E+S++C+ F L+G
Sbjct: 1758 MKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIG 1817
Query: 3286 SSTRICQAD----GTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHC 3339
S+ C +D G WS +P C +C +P ++G + + G + + C
Sbjct: 1818 ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYIC 1877
Query: 3340 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTL 3394
G+LL G C WS + C +C P N + +L +G +
Sbjct: 1878 DPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYV 1934
Query: 3395 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
C+ G+ L G + C++D+ W + C
Sbjct: 1935 TLKCEDGYTLEGSPWSQ-CQADDRWDPPLAKC 1965
Score = 299 bits (766), Expect = 3e-80
Identities = 244/822 (29%), Positives = 336/822 (40%), Gaps = 94/822 (11%)
Query: 2679 TKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSY 2737
T + + C PGY G P SI CL N W+ +R C+ SC P P NG + +
Sbjct: 67 TYLNYECRPGYSGR-PFSIICLKNSVWTGAKDR--CRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 2738 GSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQVIG---E 2791
GS ++C G+ L+GS+ C+ SG +W C CG+P I NG I E
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 2792 NYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PVSCGHPG- 2839
N+ Y V Y+CNPG F L+G C + + WSG P C+ P C P
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 2840 -SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGI 2898
+ I + + F+ N+VV F C G++M+GP + +CQA +W P C V C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPD 302
Query: 2899 PANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH- 2957
+++R + + NF+ G VFY C PGY L G++ + C P G W P C + C
Sbjct: 303 VLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 2958 -PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDAT 3013
+ VL G+ V + C L G S+ C L G W+ S P C +
Sbjct: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC--EQI 419
Query: 3014 GTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA----NGS 3061
P P H + F TV Y CD T + L G C + NG
Sbjct: 420 FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGV 479
Query: 3062 WTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSV 3112
W+ P C + C P T N F I +S+ Y C Y P
Sbjct: 480 WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY-YGRPFS 533
Query: 3113 RQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSR 3171
C N WS C SC P P NG+ + D VG ++Y C G+ L G
Sbjct: 534 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH--RLIGHS 591
Query: 3172 IRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPG--- 3222
C ++G WS P C+ + C PP I+NG T NF +G ++Y C+PG
Sbjct: 592 SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGG 651
Query: 3223 ---YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKREGKSFIYQ 3270
+EL + C N G WSG PQC +P C P GI R F
Sbjct: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR--SLFSLN 709
Query: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFG 3328
V F C F++ G CQA W P C C+ P H +Q +
Sbjct: 710 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAERTQRDKDN 765
Query: 3329 FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHANVVGMDL 3387
F G V + C+ G+ L+G+ + C P WS P C SC + V+
Sbjct: 766 FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVN 825
Query: 3388 PSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3427
G + + C GF L G + + ++ W VP+CE
Sbjct: 826 LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
Score = 272 bits (695), Expect = 5e-72
Identities = 266/1003 (26%), Positives = 398/1003 (39%), Gaps = 129/1003 (12%)
Query: 2529 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2584
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
Query: 2585 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2642
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
Query: 2643 HNKTPRCVVVTC---PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHG------LG 2693
N+TP C + C P+I +G + N ++ Y + V + C+PG G +G
Sbjct: 156 -NETPICDRIPCGLPPTIT-----NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 209
Query: 2694 PASIECLPNG--TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLG 2748
SI C N W P C I + P NG + S S F C G
Sbjct: 210 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 269
Query: 2749 FMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNP 2805
F++ G +C + W E E + C P +++ Q +N+ V Y C P
Sbjct: 270 FVMKGPRRVKCQALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 328
Query: 2806 GFRLIGSSVRICQQDHNWSGQLPSCVPVSC-GHPGSPIYGRT-SGNGFNFNDVVTFSCNI 2863
G+ L G++ C +WS P+C SC G + GR V F C+
Sbjct: 329 GYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 388
Query: 2864 GYLMQGPTKAQC---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVF 2920
G+ ++G + + C W+ P+C+ + C P + N + K F +G V
Sbjct: 389 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGK-PLEVFPFGKTVN 447
Query: 2921 YDCNP------GYFLFGSSVLIC----QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 2970
Y C+P + L G S + C Q NG W P P C ++ GH P + + + K
Sbjct: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLK 505
Query: 2971 -------YTFGSTVHYSCTGKRSLLGQS-SRTCQLNGHWSGSQPHCSGDATGTCGDPGTP 3022
+ G+++ Y C + G+ S TC N WS + C +C P P
Sbjct: 506 TQTNASDFPIGTSLKYEC--RPEYYGRPFSITCLDNLVWSSPKDVCK---RKSCKTPPDP 560
Query: 3023 GHGS-RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPG 3078
+G ++ + S + Y+C TG+ L G C+ +G+ W+ + P C+ + CG P
Sbjct: 561 VNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPP 620
Query: 3079 TTANGKVFRIDGTTF--SSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLP 3126
T ANG + F S V Y C G + L G CT+N G WSG P
Sbjct: 621 TIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 3127 NCTIISCGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSG 3183
C I + P NG+ D+ + + + V + CQPG+ M+ G R C W
Sbjct: 681 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEP 738
Query: 3184 VMPTCRAVTCPTPPQISNG---RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
+P+C V C PP + + + + NF G + Y C PGY+L A + C G WS
Sbjct: 739 ELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
Query: 3241 GEVPQCLPKFCGDPGIPAQGKREGKSFIYQ------SEVSFSCNFPFILVGSSTRICQAD 3294
P C K C D G+ ++ ++V F C+ F L GSS C
Sbjct: 798 PAAPTCEVKSCDD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 853
Query: 3295 G---TWSGSSPHCIEPTQTSCENPGVPRHGSQNN------TFGFQVGSVVQFHCKKGHL- 3344
G W+ S P C Q C +P V +G FG V H +G
Sbjct: 854 GMESLWNSSVPVC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSF 910
Query: 3345 -LQGSTTRTCLPDL----TWSGIQPEC-IPHSCKQPETPAHANVV----GMDLPSHGYTL 3394
L G +T C D WS P C I C+ P+ A + D P G +L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-GTSL 969
Query: 3395 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
Y C+P ++ G C + W+ +C+ S DP
Sbjct: 970 KYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDP 1010
Score = 209 bits (533), Expect = 3e-53
Identities = 241/937 (25%), Positives = 355/937 (37%), Gaps = 198/937 (21%)
Query: 2355 CQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
C PP + N + + T + F G ++ Y+C G R + ++ G P
Sbjct: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLG----------SRGRKVFELVGEP---S 1112
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK--EFDV 2471
+ C +N+ D G+ P PN C +VE G ++ F + EF
Sbjct: 1113 IYCTSND---DQVGIWSGPAPQCIIPN--KCT-PPNVENGILVSDNRSLFSLNEVVEFRC 1166
Query: 2472 LQ--VYDGP--------NIQSPVLISLS-----------GDYSSAFNIT-SNGHEVFLQW 2509
V GP N P L S S G+++ + S G EVF +
Sbjct: 1167 QPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVF--Y 1224
Query: 2510 SADHGNNKKGFRIRYIAFYCS-----TPESP--------------PHGYIISQTGGQLNS 2550
S + G + +G + +C+ +PE+P PHG ++ QL +
Sbjct: 1225 SCEPGYDLRGAA----SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGA 1280
Query: 2551 VVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG---GILTTD 2607
V + CD GFRL G S + C W+ VP C+ I C P A NG G + D
Sbjct: 1281 KVSFVCDEGFRLKGSSVSHCVLVGMR-SLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGD 1339
Query: 2608 YLVGTRVTYFCND----GYRLSSKELTTAVCQSD----GTWSN------------HNKTP 2647
G ++Y C+ G + +T C SD G WS+ H KTP
Sbjct: 1340 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1399
Query: 2648 RCVVVTCPSI--NSF------------------------ILEHGRWRIV----------- 2670
P+I N F LE+ W V
Sbjct: 1400 EQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGP 1459
Query: 2671 -----NGSHY-----EYKTKVVFSCDPGYHGLGPASIECLPNGT-WSWRNERPYCQIISC 2719
NG + ++ + V +SC+ G+ +G S CL +G +W + P C+IISC
Sbjct: 1460 PPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC 1519
Query: 2720 GELPTPPNGNKIGT-QTSY--GSTAIFTCDLG------FMLVGSAVRECLSS----GLWS 2766
PT NG+ +TS+ G+ + C G F LVG C S G+WS
Sbjct: 1520 EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 1579
Query: 2767 ESETRCLAGH-CGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2823
RC++ + C PE+ +V G + + + ++C PGF ++GS CQ + W
Sbjct: 1580 SPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 1639
Query: 2824 SGQLPSCVPVSCGHPGSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
+LP C V C P ++G + + F+ V +SC Y ++G C
Sbjct: 1640 GPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD 1698
Query: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFGSSV 2934
WS P C V +C D ++ HG N G V + C+ G+ L G S
Sbjct: 1699 WSPEAPRCTVKSCDD--------FLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSA 1750
Query: 2935 LICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGEKY---TFGSTVHYSCTGKR--- 2985
C G W+ +P C I C +P N +G + +G + Y+C
Sbjct: 1751 SHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRG 1810
Query: 2986 ---SLLGQSSRTC----QLNGHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTK 3035
+L+G+SS C Q NG WS P C C P +G S +
Sbjct: 1811 MTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPG 1870
Query: 3036 STVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT--- 3092
T+ Y CD GY+L G C G W+ CK V C P NG ++
Sbjct: 1871 MTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFP-LFMNGISKELEMKKVYH 1929
Query: 3093 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3129
+ V C +GY L G QC A+ W L CT
Sbjct: 1930 YGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCT 1966
Score = 140 bits (353), Expect = 2e-32
Identities = 326/1533 (21%), Positives = 523/1533 (34%), Gaps = 309/1533 (20%)
Query: 1334 GSTIIYGCNPGYTLHGSSLLKC-MTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1392
GS I Y C G+ L G S +C ++G W P C G ++G +S
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
Query: 1393 -FPYDN--NLRCMWMIEVDPGNIVSLQFL-----AFDTEASHDILRVWDGPPENDMLLKE 1444
F Y + RC +PG+ F + ++ D + +W GP ++ +
Sbjct: 634 NFHYGSVVTYRC------NPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
Query: 1445 ISGSLIPEGIHSTLN--IVTIQFDTDF-----YISKSGFAIQFSS---------SVATAC 1488
+ + GI + N + ++ +F ++ K ++ + S + C
Sbjct: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
Query: 1489 RDPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
+ P ++ R + D PG V + C+PGY+L+G + C + W P+ P C
Sbjct: 748 QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD---WSPAAPTCE 804
Query: 1546 APCGGNLTGS--SGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLY 1603
+ G +G +L P ++ + DF+
Sbjct: 805 VKSCDDFMGQLLNGRVLFP----------------------------VNLQLGAKVDFVC 836
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
D L GS + +ES N+ + E F
Sbjct: 837 -----DEGFQLKGSSASYCVLAGMESLWNS--------------------SVPVCEQIFC 871
Query: 1664 PGN--IMNGTRLGMD---YKLGSTVTYYCD------AGYVLQGYSTLTCIMGDDGRPGWN 1712
P I NG G + G V Y CD + L G ST+ C G W+
Sbjct: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 1713 RALP------SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC-VYSIAVPKEFVVFGQFV 1765
P C AP + + ++P S+ + C P V
Sbjct: 932 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV 991
Query: 1766 FFQTSLHDVVE---VYDGPTQQSSLLSSLSGSHSGESLPLS--SGNQITIRFTSVGPITA 1820
+ +S DV + P + ++ ++ G + S +G+++ ++ ++
Sbjct: 992 W--SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSG 1049
Query: 1821 KGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSSVLFDCNPG------YILH 1871
H+ + P C P G I F GS V + CN G + L
Sbjct: 1050 NTAHWSTKP-PICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 1872 GSIAIRCETVPNSLAQWNDSLPTCIVP--C------GGILTKRKGTILS----------P 1913
G +I C + + + W+ P CI+P C GIL ++ S P
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 1914 GYPEPYDNNLNC----VWKITVPEGAGI-QVQVVSFATEHNWDSLDFYDGGDNNAPRLGS 1968
G+ + C W+ +P + + Q EH D + G
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQE-----VF 1223
Query: 1969 YSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE--PQTPSSGIKIGD 2026
YS L + S L+ Q D S A + SC + Q P +
Sbjct: 1224 YSCEPGYDLRGAAS--LHCTPQGDWSPEA-------PRCAVKSCDDFLGQLPHGRVLFPL 1274
Query: 2027 RYMVGDVVSFQCDQGYSLQGHSHITC-MPGPVRRWNYPIPIC-LAQCGGAMSDFSGVILS 2084
+G VSF CD+G+ L+G S C + G WN +P+C C + +G
Sbjct: 1275 NLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNG--RH 1332
Query: 2085 PGFP-GNYPSSLDCTWTINLPIGFGVHLQFVN---------------FSTETIHDYLEVR 2128
G P G+ P + ++T + G+ + +S+ L VR
Sbjct: 1333 TGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVR 1392
Query: 2129 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI----------VYQA 2178
+G +T + P IP + F TSL + + F I V
Sbjct: 1393 AGHCKTPEQF-PFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1451
Query: 2179 YQLQSC-PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPL 2236
+ +SC P P PF I D G T+++ C G+ LIG+ + TCL G + W+
Sbjct: 1452 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
Query: 2237 PRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY- 2294
P CE + C T NG YS + + P G + F ++ IY
Sbjct: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL---FELVGERSIYC 1568
Query: 2295 ----DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQI------LIKFHSDFTTSGFFV 2344
D + VW P + + ++ N+ +I+F GF +
Sbjct: 1569 TSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQ---PGFVM 1625
Query: 2345 LSYHAYQL--------------RVCQPPPPVPNAE-ILTEDDEFEIGDIIRYQCLPGFTL 2389
+ H Q RVCQPPP + + E L+ D F G + Y C P + L
Sbjct: 1626 VGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDL 1685
Query: 2390 VGNAILTCRLGERLQMDGAP--PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA-W 2446
G A L C Q D +P P C V + L G +L P NLQ+ A
Sbjct: 1686 RGAASLHC----TPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLP------LNLQLGAKV 1735
Query: 2447 SISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVF 2506
S ++G+ + G + VL + ++S+ +
Sbjct: 1736 SFVCDEGFRL-------------------KGRSASHCVLAGMKALWNSSVPVCEQ----- 1771
Query: 2507 LQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL--NSVVRWAC----DRG- 2559
+C P + +G G + + +AC DRG
Sbjct: 1772 --------------------IFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGM 1811
Query: 2560 -FRLVGKSSAVCRKSSYGYHAWDAPVPACQ---AISCGIPKAPTNG---GILTTDYLVGT 2612
F L+G+SS C G W +P P C+ +C P NG G + YL G
Sbjct: 1812 TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGM 1871
Query: 2613 RVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNG 2672
++Y C+ GY L K C G WS + + V + P + I + + V
Sbjct: 1872 TISYICDPGYLLVGKGF--IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKV-- 1927
Query: 2673 SHYEYKTKVVFSCDPGYHGLGPASIECLPNGTW 2705
Y Y V C+ GY G +C + W
Sbjct: 1928 --YHYGDYVTLKCEDGYTLEGSPWSQCQADDRW 1958
Score = 80.1 bits (196), Expect = 4e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 1516 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 1550
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 1551 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 1600
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 684
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 1601 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 1648
Query: 685 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 742
P +L ++ + +N + PG + S +DL GD S
Sbjct: 1649 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
Query: 743 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 802
PE+P + + L +L L
Sbjct: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 1727
Query: 803 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 1728 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 1769
Score = 69.7 bits (169), Expect = 5e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1210
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
+ +N + PG + S +DL GD SPE+P
Sbjct: 1211 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1251
Query: 758 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 817
R ++ G+ +P F N QLG+ +S
Sbjct: 1252 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1283
Query: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 868
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 1284 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1340
Query: 869 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 923
P + S C +P +TF + H SP L
Sbjct: 1341 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1391
Query: 924 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 966
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 1392 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1451
Query: 967 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 1020
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 1452 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
Query: 1021 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1080
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 1512 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 1558
Query: 1081 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
L+ E + G S PP R IS +
Sbjct: 1559 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 1592
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 1593 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 1647
Query: 1199 AEC 1201
C
Sbjct: 1648 RVC 1650
Score = 69.3 bits (168), Expect = 7e-11
Identities = 134/623 (21%), Positives = 213/623 (34%), Gaps = 134/623 (21%)
Query: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
FS +V+ F CQ GF + G + + CQ N+W +P C C P VL + +
Sbjct: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC-----QPPPDVLHAERTQ 760
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
+N + PG + S +DL GD SP +P + +
Sbjct: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
Query: 758 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 794
L N +L +++F D +G + +Y E C
Sbjct: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
Query: 795 PDPGIPINARRFG---DNFQLGSSISVICEEG-----FIKTQGTETITCIL-MDGKVMWS 845
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 846 GLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN 905
P+CG GH A P H + F + +T+ N
Sbjct: 932 SPAPRCGIL--GHCQA---------------------------PDHFL---FAKLKTQTN 959
Query: 906 YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTV 965
+ G +L Y G FS + L++++
Sbjct: 960 ASDFPI--GTSLKYECRPEYYGRP-----FSITCLDNLVWSSPKD-------------VC 999
Query: 966 NTYSCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNHWWSHPLP 1021
SC P PV+G + D +GS +++SC +G+RL S E +L WS P
Sbjct: 1000 KRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 1022 TCDAL-CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV-THGKGV--QFNFHTFHLEDH 1077
C + CG +G +S F+ S+ T+ ++ + G+ V + + +
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSV-VTYRCNLGSRGRKVFELVGEPSIYCTSN 1118
Query: 1078 HDYLLITENGSFTQPLARLTGSDLPPTINAGLYGN-------------FRAQLRFI--SD 1122
D + I S P + PP + G+ + FR Q F+
Sbjct: 1119 DDQVGI---WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 1175
Query: 1123 FSISYEGFNITFSEYN--LEPCEDPGIPQYGSRIGF---NFGIGDTLTFSCSSGYRLEGT 1177
+ + N E C+ P +G NF G + +SC GY L G
Sbjct: 1176 RRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
Query: 1178 SEIICLGGGRRVWSAPLPRCVAE 1200
+ + C G WS PRC +
Sbjct: 1236 ASLHCTPQGD--WSPEAPRCAVK 1256
Score = 65.9 bits (159), Expect = 7e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 654 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 693
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 969
Query: 694 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 749
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 970 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1014
Query: 750 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 800
T +V S + + H L A+ +SG + + P G+P
Sbjct: 1015 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1073
Query: 801 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 850
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 1074 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
Query: 851 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 908
C P C + +G+++S + SLN +PG +K LN
Sbjct: 1132 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 960
E+ + P +G P + S + ++ + G +H
Sbjct: 1188 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1247
Query: 961 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1014
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
Query: 1015 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1358
Query: 1066 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1121
FN T D H NG ++ P R S F + I+
Sbjct: 1359 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
Query: 1122 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1156
DF S++YE F FS LE C P P G I
Sbjct: 1413 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
Query: 1157 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1214
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1532
Query: 1215 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1274
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1533 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 1582
Query: 1275 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1310
R + T N + + N E GF +V + +
Sbjct: 1583 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 1642
Query: 1311 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1364
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 1643 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 1700
Query: 1365 YPLPSCIAECGGRFKGE-SSGRILSP 1389
P C + F G+ GR+L P
Sbjct: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLP 1726
Score = 65.1 bits (157), Expect = 1e-09
Identities = 152/670 (22%), Positives = 244/670 (36%), Gaps = 117/670 (17%)
Query: 808 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 859
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
Query: 860 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 912
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
Query: 913 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 970
P++L + Q +F S Y L + R + T SC
Sbjct: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
Query: 971 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 1025
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
Query: 1026 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1083
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
Query: 1084 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1128
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
Query: 1129 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1169
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
Query: 1170 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1226
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
Query: 1227 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1277
+ + + G G + F L + D + I+ G + T ++
Sbjct: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
Query: 1278 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1321
L S + L+ +EF +G + V EL C P +
Sbjct: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
Query: 1322 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1380
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
Query: 1381 E-SSGRILSP 1389
+ +GR+L P
Sbjct: 814 QLLNGRVLFP 823
Score = 63.9 bits (154), Expect = 3e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
C G T T+ +F ++TN+ NF + + Y
Sbjct: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
Query: 625 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
Query: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 740
S P VL + + +N + PG + S +DL G
Sbjct: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 741 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 790
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 791 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 828
E CP P + N R G + F G +++ C+
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
Query: 829 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 862
G TI C G +WS P+CG GH AP
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
Score = 60.8 bits (146), Expect = 2e-08
Identities = 136/619 (21%), Positives = 200/619 (32%), Gaps = 134/619 (21%)
Query: 648 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 699
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
Query: 700 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 756
G N C DP SF D ES + G+ S +P G +
Sbjct: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
Query: 757 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 795
P H T+ S L+++ GR F+IT + C
Sbjct: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
Query: 796 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 853
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
Query: 854 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 908
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 963
+ + GP + V L S + ++ L R GF + +
Sbjct: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
Query: 964 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 1011
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 1012 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1069
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
Query: 1070 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1129
L GS + AG+ + + +
Sbjct: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
Query: 1130 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1180
C P + G G F G + ++C + + L G S I
Sbjct: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
Query: 1181 ICLGG--GRRVWSAPLPRC 1197
C G VWS+P PRC
Sbjct: 919 RCTSDPQGNGVWSSPAPRC 937
Score = 60.5 bits (145), Expect = 3e-08
Identities = 132/647 (20%), Positives = 223/647 (34%), Gaps = 127/647 (19%)
Query: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSCIA 1372
C +P P G +G GS I Y C GY L GSS C+ +G+ WD P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1373 ECGGRFKGESSGRILSPGYP-FPYDN--NLRCMWMIEVDPGNIVSLQFL-----AFDTEA 1424
G ++G +S F Y + RC +PG+ F + +
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRC------NPGSGGRKVFELVGEPSIYCTS 217
Query: 1425 SHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN--IVTIQFDTDF-----YISKSGFA 1477
+ D + +W GP ++ + + + GI + N + ++ +F ++ K
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
Query: 1478 IQFSS---------SVATACRDPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEER 1525
++ + S + C+ P ++ R + D PG V + C+PGY+L+G
Sbjct: 278 VKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 337
Query: 1526 ITCIQVENRYFWQPSPPVCIAPCGGNLTGS--SGFILSPNFPHPYPHSRDCDWTITVNAD 1583
+ C + W P+ P C + G +G +L P
Sbjct: 338 MRCTPQGD---WSPAAPTCEVKSCDDFMGQLLNGRVLFP--------------------- 373
Query: 1584 YVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS 1643
++ + DF+ D L GS + +ES N+
Sbjct: 374 -------VNLQLGAKVDFVC-----DEGFQLKGSSASYCVLAGMESLWNS---------- 411
Query: 1644 VSYTGFHLEYKAKLRESCFDPGN--IMNGTRLGMD---YKLGSTVTYYCD------AGYV 1692
+ E F P I NG G + G TV Y CD +
Sbjct: 412 ----------SVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 1693 LQGYSTLTCIMGDDGRPGWNRALP------SCHAPCGSRSTGSEGTVLSPNYPKNYSVGH 1746
L G ST+ C G W+ P C AP + + ++P S+ +
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 1747 NC-VYSIAVPKEFVVFGQFVFFQTSLHDVVE---VYDGPTQQSSLLSSLSGSHSGESLPL 1802
C P V+ +S DV + P + ++ ++ G +
Sbjct: 522 ECRPEYYGRPFSITCLDNLVW--SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 1803 S--SGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVG 1857
S +G+++ ++ ++ H+ + P C P G I F G
Sbjct: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKP-PICQRIPCGLPPTIANGDFISTNRENFHYG 638
Query: 1858 SSVLFDCNPG------YILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1898
S V + CNPG + L G +I C + + + W+ P CI+P
Sbjct: 639 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 60.5 bits (145), Expect = 3e-08
Identities = 142/626 (22%), Positives = 212/626 (33%), Gaps = 125/626 (19%)
Query: 137 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
Query: 196 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 250
+ CG ++G S + N +H + T+ PG +F
Sbjct: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
Query: 251 KYDYLEIEGSEPPTIWLSGMNIPPP------IISNKNWLRLHFVTDSNHRYRGFSAPYQG 304
D + I P + PP + N++ L+ V + F
Sbjct: 668 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVE-------FRCQPGF 720
Query: 305 SSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVT----- 359
L + V P DV + T S Q V +
Sbjct: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
Query: 360 SLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFK-SRG 418
LR + T + SP A T + Q+ + L V ++ +DF G
Sbjct: 781 DLRGAASMRCTPQGDWSP-AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEG 839
Query: 419 FKLFPGKDNSNKFSILNEGGIKTASN---------LCPDPGEPENGKRIGSD---FSLGS 466
F+L K +S + +L G+++ N CP P NG+ G F G
Sbjct: 840 FQL---KGSSASYCVL--AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGK 894
Query: 467 TVQFSCD------EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 520
V ++CD + L G +I C + WS P C + + Q P
Sbjct: 895 AVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL---GHCQAPDHFLF 951
Query: 521 SPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQV 580
+ + +NA + T++ + F ++T D P+ V +
Sbjct: 952 A---KLKTQTNASDFPIGTSLKYECRPEYYGRPF-------SITCLDNLVWSSPKDVCKR 1001
Query: 581 LTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYK----------------------- 617
+ PD + M +H+ TD VGS ++NY
Sbjct: 1002 KSCKTPPDPVNGM-----VHVITDIQVGS---RINYSCTTGHRLIGHSSAECILSGNTAH 1053
Query: 618 ------EIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIG 658
++ CG P T I GD S NR+ V+ + C G FEL+G
Sbjct: 1054 WSTKPPICQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVG 1109
Query: 659 EKSIVCQENNQ----WSANIPICIFP 680
E SI C N+ WS P CI P
Sbjct: 1110 EPSIYCTSNDDQVGIWSGPAPQCIIP 1135
Score = 60.1 bits (144), Expect = 4e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 769 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 817
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
Query: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 876
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
Query: 877 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 931
S+ PG + FE N D + + GP +P N P
Sbjct: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
Query: 932 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 974
L S + ++ L R GF + + +N + C P
Sbjct: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
Query: 975 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 1031
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 1032 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1089
G +G +L +P +L VD +G Q
Sbjct: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
Query: 1090 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1149
L GS + AG+ + + + C P +
Sbjct: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
Query: 1150 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1197
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 59.7 bits (143), Expect = 5e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 1142 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1198
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1199 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1248
CG T G +S N EN H + + + G G + F L
Sbjct: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
Query: 1249 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1303
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 1304 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1351
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
Query: 1352 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1410
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
Query: 1411 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1466
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
Query: 1467 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1520
G TV + CDP ++L
Sbjct: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
Query: 1521 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1576
GE I C + W P C G G +P+ F + D+
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
Query: 1577 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1623
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
Query: 1624 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1675
RI S T H L S +G + K R C P I NG +
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
Query: 1676 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1721
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 49.3 bits (116), Expect = 7e-05
Identities = 70/277 (25%), Positives = 98/277 (35%), Gaps = 34/277 (12%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNT-AHWSTKPPICQ 1062
Query: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
G P + P+ ++VS + ++ + E GF
Sbjct: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
Query: 613 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 660
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 1177 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 661 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 695
S+ C WS P C +F P G VL P
Sbjct: 1237 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
Score = 48.1 bits (113), Expect = 2e-04
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 654 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 690
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 1360 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1419
Query: 691 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 743
T L+ + GY + N +W+ + D R K P
Sbjct: 1420 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1460
Query: 744 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 795
P G T + S + S + RL + G N+T++ C
Sbjct: 1461 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1520
Query: 796 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 846
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 1521 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 1580
Query: 847 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 901
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 1581 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 1640
Query: 902 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 959
+L + P +L L + Q +F S Y L +
Sbjct: 1641 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
Query: 960 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1014
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 1760
Query: 1015 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1074
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 1761 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 1807
Query: 1075 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1118
+ + LI E NG ++ P R PP I G Y L
Sbjct: 1808 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 1866
Query: 1119 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1160
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 1867 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 1924
Query: 1161 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1199
GD +T C GY LEG+ C R W PL +C +
Sbjct: 1925 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 1967
Score = 47.0 bits (110), Expect = 3e-04
Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 34/277 (12%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA-AHWSTKPPICQ 612
Query: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
G P + P+ ++VS + ++ + E GF
Sbjct: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 613 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 660
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
Query: 661 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 695
S+ C WS P C +F + G VL P
Sbjct: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
Score = 46.6 bits (109), Expect = 5e-04
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 131 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
Query: 190 FPVPIC 195
PIC
Sbjct: 156 NETPIC 161
Score = 46.6 bits (109), Expect = 5e-04
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 131 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 1450 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1508
Query: 190 FPVPIC 195
PIC
Sbjct: 1509 KKAPIC 1514
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 1487 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1544
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 1545 IAPCGGNLTGSSGFILSPN 1563
PCG T ++G +S N
Sbjct: 163 RIPCGLPPTITNGDFISTN 181
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 436 EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
E + + S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C +
Sbjct: 1187 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD- 1245
Query: 493 FAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 522
WS P C VK+C L Q P G P
Sbjct: 1246 ---WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
Score = 44.3 bits (103), Expect = 0.002
Identities = 83/385 (21%), Positives = 138/385 (35%), Gaps = 90/385 (23%)
Query: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 212
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 1416 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1469
Query: 213 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 270
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 1470 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1522
Query: 271 NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAV 330
P ISN ++ SN+R + + +T+ TG E G ++
Sbjct: 1523 ----PTISNGDFY-------SNNR-----TSFHNGTVVTYQCHTGPDGEQLFELVGERSI 1566
Query: 331 ASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHP---ADTQSTRR 387
T S++ +V V S SP P + + T
Sbjct: 1567 YCT-----------------SKDDQVGVWS---------------SPPPRCISTNKCTAP 1594
Query: 388 RPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPG--KDNSNKFSILNEGG----IKT 441
+A ++ + +T ++ F+ PG S+ G +
Sbjct: 1595 EVENAIRVPGNRSFFTLTEIIR---------FRCQPGFVMVGSHTVQCQTNGRWGPKLPH 1645
Query: 442 ASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSD 498
S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C + WS
Sbjct: 1646 CSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD----WSP 1701
Query: 499 HRPVCKVKTCGSNL-QGPSGTFTSP 522
P C VK+C L Q P G P
Sbjct: 1702 EAPRCTVKSCDDFLGQLPHGRVLLP 1726
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 436 EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
E + + S +C PD E +R +FS G V +SC+ Y L+GA S+ C +
Sbjct: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD- 345
Query: 493 FAAWSDHRPVCKVKTC 508
WS P C+VK+C
Sbjct: 346 ---WSPAAPTCEVKSC 358
Score = 37.0 bits (84), Expect = 0.36
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 446 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 1903
Query: 503 CKVKTC 508
CK C
Sbjct: 1904 CKEVNC 1909
Score = 36.6 bits (83), Expect = 0.47
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 19/113 (16%)
Query: 402 AVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPD--------PGEPE 453
+VVT+R + SRG K+F + + N+ + S P P E
Sbjct: 1089 SVVTYRC----NLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 1144
Query: 454 NGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
NG + + FSL V+F C +V++G + + CQ + + W P C
Sbjct: 1145 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 1193
Score = 35.0 bits (79), Expect = 1.4
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 24/105 (22%)
Query: 419 FKLFPGKDNSNKFSILNEGGIKTASN--------------LCPD---PGEPENGKRIGSD 461
++ PG F ++ E I SN + P+ P ENG + +
Sbjct: 193 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 252
Query: 462 ---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
FSL V+F C +V++G + + CQ + + W P C
Sbjct: 253 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
Score = 33.9 bits (76), Expect = 3.0
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 461 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 508
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 1728 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 1774
Score = 33.5 bits (75), Expect = 4.0
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 2028 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2075
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 1973
Score = 33.1 bits (74), Expect = 5.2
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
Query: 185 TASWDFPVPICR---AEDACGGTMRG 207
W P C +D G + G
Sbjct: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG 368
Score = 33.1 bits (74), Expect = 5.2
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
Query: 185 TASWDFPVPICR---AEDACGGTMRG 207
W P C +D G + G
Sbjct: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG 818
Score = 32.7 bits (73), Expect = 6.8
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 185 TASWDFPVPICRAEDAC 201
W P P C + C
Sbjct: 672 VGIWSGPAPQCIIPNKC 688
Score = 32.7 bits (73), Expect = 6.8
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1121
Query: 185 TASWDFPVPICRAEDAC 201
W P P C + C
Sbjct: 1122 VGIWSGPAPQCIIPNKC 1138
Score = 32.3 bits (72), Expect = 8.9
Identities = 20/73 (27%), Positives = 25/73 (34%), Gaps = 9/73 (12%)
Query: 138 CGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVNTASW 188
CG P G T F G + Y C G + L G P + C +N W
Sbjct: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
Query: 189 DFPVPICRAEDAC 201
P P C + C
Sbjct: 226 SGPAPQCIIPNKC 238
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 353 bits (905), Expect = 2e-96
Identities = 288/975 (29%), Positives = 421/975 (43%), Gaps = 106/975 (10%)
Query: 2529 CSTPESPPHGYI-ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
C +P +G I T + +V+R++C FRL+G+ S +C WD P P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2588 QAI----SCGIPKAPTNGGIL-TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2642
+ SC P P I +T Y G VT+ C + ++ + + CQ++ W
Sbjct: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK--SVWCQANNMW-G 139
Query: 2643 HNKTPRCVVV---TCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIEC 2699
+ P CV V CP++ ++ +G N V +SC+ GY +G I C
Sbjct: 140 PTRLPTCVSVFPLECPALP--MIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINC 197
Query: 2700 LPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2758
L +G WS P C+ C L PNG K G TA F CD G+ L G
Sbjct: 198 LSSGKWS--AVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 2759 CLSSG---LWSESETRCLAGHCGIPELIVNGQVIGE---NYGYRDTVVYQCNP------G 2806
C+ +G W++ C C P I+NG+ IG N Y V Y C+P
Sbjct: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2807 FRLIGSSVRIC----QQDHNWSGQLPSC----VPVSCGHP----GSPIYGRTSGNGFNFN 2854
F LIG S C Q+ WSG P C V C HP G + G+ + + +N
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQK--DRYTYN 372
Query: 2855 DVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2914
D V F+C G+ ++G + +C A W P+C+ C P N ++E + F
Sbjct: 373 DTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDR-HMVRFD 430
Query: 2915 YGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF- 2973
GT + Y CNPGY L G + C G W P+P+C + C G +L+ ++ F
Sbjct: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG---RQLLTKPQHQFV 487
Query: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQES--- 3030
V+ SC L G + CQ W C TC P +G+ S
Sbjct: 488 RPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCK---EITCPPPPVIYNGAHTGSSLE 544
Query: 3031 NFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECK----AVQCGN 3076
+F +TV Y C+ G + L G C +N G+W+G P CK AVQC +
Sbjct: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
Query: 3077 PGTTANGKVFRIDGTT----FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIIS 3132
ANG ++I G ++ +V + C G+ L G S +C A+ TW +P C
Sbjct: 605 V-HIANG--YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGC 661
Query: 3133 CGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR 3189
PG+ +G G + +V G V Y C PGY L G++ C +G WS P C
Sbjct: 662 QSPPGL-HHGRHTGGNTVFFVSGMTVDYTCDPGYL--LVGNKSIHCMPSGNWSPSAPRCE 718
Query: 3190 AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTC--VGNGTWSGEVPQCL 3247
TC Q G+ + ++ C GY+L+ A C NG W ++P C
Sbjct: 719 E-TCQHVRQSLQELPAGSRVE---LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
Query: 3248 PKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQAD----GTWSGS 3300
C P + GK G ++F+Y +EVS+ C+ F L+G C++D G+WSG
Sbjct: 775 VIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 834
Query: 3301 SPHCI-EPTQTSCENPGVPRHGSQNNT--FGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL 3357
SP C+ P T C NP V +HG + N + +V C G ++ GS C D
Sbjct: 835 SPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN 893
Query: 3358 TWSGIQPECIPHS---CKQPETPAHANVVGMDLP--SHGYTLIYTCQPGFFLAGGTEHRV 3412
TW P CI + C P + N G ++ S G +++Y+C G+ L G +
Sbjct: 894 TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEALLL 952
Query: 3413 CRSDNTWTGKVPICE 3427
C + TW+ P C+
Sbjct: 953 CTHEGTWSQPAPHCK 967
Score = 335 bits (860), Expect = 4e-91
Identities = 286/1071 (26%), Positives = 439/1071 (40%), Gaps = 137/1071 (12%)
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ--MDGAPPVC 2412
C PPP+ N I +G +IRY C F L+G L C +++ D P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2413 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2472
+ Y + Y + C I V GY I
Sbjct: 83 E--------------------YFNKYSS---CPEPI-VPGGYKIRG-------------- 104
Query: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHE-VFLQWSADHGNNKKGFRIRYIAFYCST 2531
+P S ++ N + NG++ V+ Q + G + + C
Sbjct: 105 --------STPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
Query: 2532 PESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2589
+G+ S+ G + V ++C+ G+ LVG+ C S W A P C+
Sbjct: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG----KWSAVPPTCEE 212
Query: 2590 ISCGIPKAPTNGGILTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSNHNKTP 2647
C NG + L VG +FC++GYRL + V G W+ K P
Sbjct: 213 ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT---KMP 269
Query: 2648 RCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDP------GYHGLGPASIECLP 2701
C + CPS + +GR + ++ Y + V ++CDP + +G +++ C
Sbjct: 270 VCEEIFCPSPPPIL--NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV 327
Query: 2702 NG--TWSWRNERPYCQI-ISCGELPTPP--NGNKIGTQT---SYGSTAIFTCDLGFMLVG 2753
+ T +W P C++ S + P P G + Q +Y T IF C GF L G
Sbjct: 328 DSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387
Query: 2754 SAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRD---TVVYQCNPGFRLI 2810
S C + G W S C C P I+NGQ + D ++ Y CNPG+ L+
Sbjct: 388 SKQIRCNAQGTWEPSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV 446
Query: 2811 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGP 2870
G C + W+ +P C +C G + + + F DV + SC GY + G
Sbjct: 447 GEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQ-HQFVRPDVNS-SCGEGYKLSGS 504
Query: 2871 TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRE-SKIEHGNFTYGTVVFYDCNPG--- 2926
+CQ W +CK + C P + N S +E +F YGT V Y CNPG
Sbjct: 505 VYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLE--DFPYGTTVTYTCNPGPER 562
Query: 2927 ---YFLFGSSVLICQPN----GQWDKPLPEC----IMIDCGHPGVPPNAVLSGEK--YTF 2973
+ L G S + C N G W P P C + + C H + +SG++ Y +
Sbjct: 563 GVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFY 622
Query: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-- 3031
TV + C +L G S C+ + W P C C P HG N
Sbjct: 623 NDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG----CQSPPGLHHGRHTGGNTV 678
Query: 3032 -FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG 3090
F + TV Y CD GY+L G++ C+ +G+W+ P C+ C + + +
Sbjct: 679 FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQH----VRQSLQELPA 733
Query: 3091 TTFSSSVIYSCMEGYILSGPSVRQC--TANGTWSGTLPNCTIISCGDPGIPANGLRYG-- 3146
+ V SC +GY L+G + + C NG W +P C +I C P + NG G
Sbjct: 734 GSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMM 793
Query: 3147 -DDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN----GTWSGVMPTCR----AVTCPTPP 3197
++++ G VSY C G+ L G + C + G+WSG P C CP P
Sbjct: 794 AENFLYGNEVSYECDQGFY--LLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 851
Query: 3198 QISNGRLEGTNFDWGFS-ISYI-CSPGYELSFPAVLTCVGNGTWSGEVPQCLPK-FCGDP 3254
+L T+ + + I Y+ C+PG+ ++ V+ C + TW VP C+ K F G P
Sbjct: 852 VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
Query: 3255 GIPA--QGKREGKSFIYQS---EVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3309
P G G + S + +SC+ ++LVG + +C +GTWS +PHC E
Sbjct: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
Query: 3310 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS 3360
+S + + G + +Q G+VV C+ G++L+GS C D W+
Sbjct: 972 SSPADMDGIQKGLEPRKM-YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 1021
Score = 281 bits (718), Expect = 1e-74
Identities = 235/798 (29%), Positives = 342/798 (42%), Gaps = 107/798 (13%)
Query: 2717 ISCGELPTPPNG--NKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS----GLWSESET 2770
ISCG P NG + T + G+ ++C F L+G C++ G W +
Sbjct: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
Query: 2771 RC--LAGHCGIPELIVNG--QVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSG 2825
+C + PE IV G ++ G Y + D+V + C F + G+ CQ ++ W
Sbjct: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
Query: 2826 -QLPSCV---PVSCGHPGSPIYGRTSGNGFNFNDV-----VTFSCNIGYLMQGPTKAQCQ 2876
+LP+CV P+ C P P+ N + VT+SC GYL+ G C
Sbjct: 141 TRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 198
Query: 2877 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2936
++ +WS PP C+ C G N K + E G + C+ GY L G
Sbjct: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVK---EPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 2937 CQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGE-------KYTFGSTVHYSCTGKRS 2986
C GQ W K +P C I C P PP +L+G ++GS V Y+C
Sbjct: 256 CVIAGQGVAWTK-MPVCEEIFC--PSPPP--ILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
Query: 2987 ------LLGQSSRTC----QLNGHWSGSQPHCSGDATGT-CGDPG--TPGHGSRQESNFR 3033
L+G+S+ C Q G WSG P C + C P S Q+ +
Sbjct: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
Query: 3034 TKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGK-----VFRI 3088
TV +AC G+ L GS++ C A G+W P C+ +C P NG+ + R
Sbjct: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRF 429
Query: 3089 DGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD 3148
D T S+ YSC GY+L G QCT+ G W+ +P C + +C G L
Sbjct: 430 DPGT---SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG--RQLLTKPQH 484
Query: 3149 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT- 3207
V +V+ C GY +L+GS + C W + C+ +TCP PP I NG G+
Sbjct: 485 QFVRPDVNSSCGEGY--KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 3208 --NFDWGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQC----LPKFC 3251
+F +G +++Y C+PG + L + + C N GTWSG P C L C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 3252 GDPGIPAQGKREGKS--FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3309
I K GK + Y V+F C F L GSS C+AD TW P C +
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC----E 658
Query: 3310 TSCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI 3367
C++P HG + NT F G V + C G+LL G+ + C+P WS P C
Sbjct: 659 KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC- 717
Query: 3368 PHSCKQPETPAHANVVGMDLPSHGYTLIY--TCQPGFFLAGGTEHRVCR--SDNTWTGKV 3423
ET H +LP+ + +CQ G+ L G +++C+ + W K+
Sbjct: 718 ------EETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHA-YQMCQDAENGIWFKKI 770
Query: 3424 PICEAGSKILVKDPRPAL 3441
P+C K++ P P +
Sbjct: 771 PLC----KVIHCHPPPVI 784
Score = 253 bits (646), Expect = 2e-66
Identities = 209/693 (30%), Positives = 291/693 (41%), Gaps = 86/693 (12%)
Query: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDY 2608
N V +AC GF L G C W+ P C+ C P NG
Sbjct: 372 NDTVIFACMFGFTLKGSKQIRCNAQG----TWEPSAPVCEK-ECQAPPNILNGQKEDRHM 426
Query: 2609 L---VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHG 2665
+ GT + Y CN GY L +E + C S+G W+ P+C V C + G
Sbjct: 427 VRFDPGTSIKYSCNPGYVLVGEE--SIQCTSEGVWTP--PVPQCKVAACEAT-------G 475
Query: 2666 RWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTP 2725
R + H + V SC GY G EC GT W E C+ I+C P
Sbjct: 476 RQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQEC--QGTIPWFMEIRLCKEITCPPPPVI 533
Query: 2726 PNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRECLSS----GLWSESETRC 2772
NG G+ YG+T +TC+ G F L+G + C S+ G WS C
Sbjct: 534 YNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
Query: 2773 ----LAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQ 2826
LA C + ++ G+ Y Y DTV ++C GF L GSS C+ D+ W +
Sbjct: 594 KLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 2827 LPSCVPVSCGHPGSPIYGRTSGNGFNF---NDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2883
+P C C P +GR +G F V ++C+ GYL+ G C + WS
Sbjct: 654 IPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSP 712
Query: 2884 PPPMCKV----VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQP 2939
P C+ V S +PA S+ E +V C GY L G + +CQ
Sbjct: 713 SAPRCEETCQHVRQSLQELPAGSRVE------------LVNTSCQDGYQLTGHAYQMCQD 760
Query: 2940 --NGQWDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQSSRT 2994
NG W K +P C +I C P V N +G E + +G+ V Y C LLG+
Sbjct: 761 AENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQ 820
Query: 2995 CQLN----GHWSGSQPHCSGDATGT-CGDPGTPGHG---SRQESNFRTKSTVRYACDTGY 3046
C+ + G WSG P C T C +P HG ++ S + V C+ G+
Sbjct: 821 CRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGF 879
Query: 3047 ILHGSEERTCLANGSWTGRQPEC--KA-VQCGNPGTTANGKVFRIDGTTFSS--SVIYSC 3101
I++GS C + +W P C KA + C P T NG + FS S++YSC
Sbjct: 880 IMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSC 939
Query: 3102 MEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDP----GIPANGLRYGDDYVVGQNVSY 3157
+GY+L G ++ CT GTWS P+C ++C P GI GL Y G V+
Sbjct: 940 DQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGI-QKGLEPRKMYQYGAVVTL 998
Query: 3158 MCQPGYTMELNGSRIRTCTINGTWSGVMPTCRA 3190
C+ GY +E GS C + W+ + CR+
Sbjct: 999 ECEDGYMLE--GSPQSQCQSDHQWNPPLAVCRS 1029
Score = 225 bits (573), Expect = 7e-58
Identities = 188/661 (28%), Positives = 270/661 (40%), Gaps = 75/661 (11%)
Query: 2828 PSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQC----QANRQW 2881
P + +SCG P + GR S V+ +SC+ + + G C + + W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 2882 SHPPPMCKVVN----CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2937
P P C+ N C +P +P K + +G V + C + + G+ + C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP---YRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 2938 QPNGQWDKP-LPECIMI---DCGHPGVPPNAVLSGE---KYTFGSTVHYSCTGKRSLLGQ 2990
Q N W LP C+ + +C + N + E G +V YSC L+G+
Sbjct: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Query: 2991 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTVRYACDTGYILH 3049
C +G WS P C C G +G +E R T + CD GY L
Sbjct: 193 KIINCLSSGKWSAVPPTCE---EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
Query: 3050 GSEERTCLANG---SWTGRQPECKAVQCGNPGTTANGKVF--RIDGTTFSSSVIYSC--- 3101
G C+ G +WT + P C+ + C +P NG+ + ++ S V Y+C
Sbjct: 250 GPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
Query: 3102 -MEG--YILSGPSVRQCTAN----GTWSGTLPNCTI----ISCGDPGIPANGLRYG--DD 3148
EG +IL G S +CT + GTWSG P C + + C P I + G D
Sbjct: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR 368
Query: 3149 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG-- 3206
Y V + C G+T L GS+ C GTW P C C PP I NG+ E
Sbjct: 369 YTYNDTVIFACMFGFT--LKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRH 425
Query: 3207 -TNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGK 3265
FD G SI Y C+PGY L + C G W+ VPQC C G K + +
Sbjct: 426 MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
Query: 3266 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3325
+ +V+ SC + L GS + CQ W C E T C P V +G+
Sbjct: 486 --FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT---CPPPPVIYNGAHTG 540
Query: 3326 TF--GFQVGSVVQFHCKKG-------HLLQGSTTRTCLPDL---TWSGIQPEC----IPH 3369
+ F G+ V + C G L+ ST R D TWSG P C +
Sbjct: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
Query: 3370 SCKQPETPAHANVVGMDLP-SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3428
C + G + P + T+ + C GF L G ++ R C++DNTW ++P+CE
Sbjct: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR-CKADNTWDPEIPVCEK 659
Query: 3429 G 3429
G
Sbjct: 660 G 660
Score = 206 bits (525), Expect = 3e-52
Identities = 158/570 (27%), Positives = 242/570 (42%), Gaps = 68/570 (11%)
Query: 2552 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG---GILTTDY 2608
V +C G++L G C+ G W + C+ I+C P NG G D+
Sbjct: 491 VNSSCGEGYKLSGSVYQECQ----GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
Query: 2609 LVGTRVTYFCNDG----YRLSSKELTTAVCQSD----GTWSNHNKTPRC----VVVTCPS 2656
GT VTY CN G S +T C S+ GTWS P C + V C
Sbjct: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG--PAPLCKLSLLAVQCSH 604
Query: 2657 INSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQI 2716
++ + +G + Y Y V F C G+ G + I C + TW E P C+
Sbjct: 605 VH---IANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD--PEIPVCEK 659
Query: 2717 ISCGELPTPPNGNKIGTQTSY---GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC- 2772
C P +G G T + G T +TCD G++LVG+ C+ SG WS S RC
Sbjct: 660 -GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE 718
Query: 2773 -LAGHC--GIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHN--WSGQL 2827
H + EL +V + V C G++L G + ++CQ N W ++
Sbjct: 719 ETCQHVRQSLQELPAGSRV--------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKI 770
Query: 2828 PSCVPVSCGHPGSPIYGRTSG---NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ---- 2880
P C + C P + G+ +G F + + V++ C+ G+ + G K QC+++ +
Sbjct: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS 830
Query: 2881 WSHPPPMC----KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2936
WS P P C V C +P + K H +++ +V+ DCNPG+ + GS V+
Sbjct: 831 WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT--HSAYSHNDIVYVDCNPGFIMNGSRVIR 888
Query: 2937 CQPNGQWDKPLPECI---MIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQ 2990
C + W +P CI I C P PN +G +++ G ++ YSC L+G+
Sbjct: 889 CHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGE 948
Query: 2991 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHG 3050
+ C G WS PHC + D G ++ + V C+ GY+L G
Sbjct: 949 ALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEG 1008
Query: 3051 SEERTCLANGSWTGRQPECKA-----VQCG 3075
S + C ++ W C++ V CG
Sbjct: 1009 SPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
Score = 157 bits (397), Expect = 2e-37
Identities = 271/1162 (23%), Positives = 401/1162 (34%), Gaps = 283/1162 (24%)
Query: 1825 FVYQAVPRTSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1882
F+ P C S P GR AVG+ + + C+ + L G ++ C T
Sbjct: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
Query: 1883 NSLAQWNDSLPTC------------IVPCG----GILTKRKGTILSPGYPEPYDNNLN-C 1925
W+ P C IVP G G R G ++ + N N
Sbjct: 70 KVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKS 129
Query: 1926 VWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYS-GTTIPHLLNSTSNN 1984
VW ++ +L G + + +GS + G ++ + S +
Sbjct: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTY---SCESG 186
Query: 1985 LYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSG------IKIGDRYMVGDVVSFQC 2038
L + I+ ++G +++A+ +C E + S G +K VG +F C
Sbjct: 187 YLLVGEKIINCLSSG---KWSAVP-PTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFC 242
Query: 2039 DQGYSLQGHSHITCM-PGPVRRWNYPIPICLAQ-CGGAMSDFSGVILSPGFPGNYPSSLD 2096
D+GY LQG C+ G W +P+C C +G + S+
Sbjct: 243 DEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI- 300
Query: 2097 CTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHE 2156
T+T + GV+ + ST L S +T T SGP P ST+
Sbjct: 301 VTYTCDPDPEEGVNFILIGEST------LRCTVDSQKTGT----WSGPA-PRCELSTS-- 347
Query: 2157 TSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND--FTVGQTISFECFPGY 2214
CP P+ R V G +T T+ F C G+
Sbjct: 348 ------------------------AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 2215 TLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNG-------TIYSPGYPDEY---P 2264
TL G+ + C W P CE C +NG + PG +Y P
Sbjct: 384 TLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 2265 NF-----------QDCFWLVRVPPGNGIYINFTVLQ--TEPIYDFITVWDGPDQNSPQIG 2311
+ + W VP T Q T+P + F+ PD NS G
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----PDVNS-SCG 496
Query: 2312 QFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQ----PPPPV--PNAE 2365
+ G SVY + F ++R+C+ PPPPV A
Sbjct: 497 E--GYKLSGSVYQECQGTIPWF----------------MEIRLCKEITCPPPPVIYNGAH 538
Query: 2366 ILTEDDEFEIGDIIRYQCLPG------FTLVGNAILTCRLG--ERLQMDGAPPVCQVLCP 2417
+ ++F G + Y C PG F+L+G + + C ER G P+C++
Sbjct: 539 TGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL--- 595
Query: 2418 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2477
+ L + + V ++ GY S YN T+ + Y G
Sbjct: 596 -SLLAVQCSHVHIANGYKIS---------GKEAPYFYNDTV------------TFKCYSG 633
Query: 2478 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPH 2537
++ I D + W + +KG C +P H
Sbjct: 634 FTLKGSSQIRCKADNT---------------WDPEIPVCEKG---------CQSPPGLHH 669
Query: 2538 GYIISQTGGQL-----NSVVRWACDRGFRLVGKSSAVCRKSSY----------------- 2575
G TGG V + CD G+ LVG S C S
Sbjct: 670 G---RHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQ 726
Query: 2576 --------------------GY----HA-----------WDAPVPACQAISCGIPKAPTN 2600
GY HA W +P C+ I C P N
Sbjct: 727 SLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVN 786
Query: 2601 G---GILTTDYLVGTRVTYFCNDG-YRLSSKELTTAVCQSD----GTWSNHNKTPRCV-- 2650
G G++ ++L G V+Y C+ G Y L K+L C+SD G+WS +P+C+
Sbjct: 787 GKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQ---CRSDSKGHGSWS--GPSPQCLRS 841
Query: 2651 --VVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2708
V CP+ ++HG S Y + V C+PG+ G I C + TW
Sbjct: 842 PPVTRCPNPE---VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV-- 896
Query: 2709 NERPYC---QIISCGELPTPPNGNKIG---TQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2762
P C I C P PNGN G + S G + +++CD G++LVG A+ C
Sbjct: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
Query: 2763 GLWSESETRCLAGHCGIP---ELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQ 2819
G WS+ C +C P + I G + Y Y V +C G+ L GS CQ
Sbjct: 957 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQS 1016
Query: 2820 DHNWSGQLPSC-----VPVSCG 2836
DH W+ L C PV CG
Sbjct: 1017 DHQWNPPLAVCRSRSLAPVLCG 1038
Score = 99.0 bits (245), Expect = 8e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 3184 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3237
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 3238 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3292
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 3293 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3347
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 3348 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3407
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 3408 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3441
R + WT K+P+CE +I P P L
Sbjct: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
Score = 85.1 bits (209), Expect = 1e-15
Identities = 182/861 (21%), Positives = 272/861 (31%), Gaps = 226/861 (26%)
Query: 1680 GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH-APCGSRSTGSEGTVLSP-- 1736
G +VTY C++GY+L G + C+ W+ P+C A C S G V P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKVKEPPI 231
Query: 1737 ---NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1793
N+ V+ GQ V + T + E++ S L+G
Sbjct: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFC-----PSPPPILNG 285
Query: 1794 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR--------------------- 1832
H G SL S I P F + ++ R
Sbjct: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELS 345
Query: 1833 TSSTQCSSVPEPRF--GRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1887
TS+ QC P P+ GR + + + +V+F C G+ L GS IRC N+
Sbjct: 346 TSAVQC---PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGT 398
Query: 1888 WNDSLPTCIVPCGG---ILTKRK----------GTIL----SPGYPEPYDNNLNC----V 1926
W S P C C IL +K GT + +PGY + ++ C V
Sbjct: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
Query: 1927 WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLY 1986
W VP Q A E L P + S G S ++Y
Sbjct: 459 WTPPVP-------QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-----KLSGSVY 506
Query: 1987 LNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCDQG-- 2041
Q I + +E +CP P +G G + + G V++ C+ G
Sbjct: 507 QECQGTIP-----WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Query: 2042 ----YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDC 2097
+SL G S I C R + P L + S V ++ G+ S +
Sbjct: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYK---ISGKEA 618
Query: 2098 TWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHET 2157
+ N + F + F GSS+ P+IP
Sbjct: 619 PYFYNDTVTFKCYSGFT-------------LKGSSQIRCKADNTWDPEIPVCE------- 658
Query: 2158 SLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND---FTVGQTISFECFPGY 2214
+ C P +G G + F G T+ + C PGY
Sbjct: 659 ------------------------KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGY 694
Query: 2215 TLIGNSALTCLHGVSRNWNHPLPRCEALC-----------GGNITAMNGTIYSPGYPDEY 2263
L+GN ++ C+ S NW+ PRCE C G+ + T GY
Sbjct: 695 LLVGNKSIHCM--PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 752
Query: 2264 PNFQDC------FWLVRVP----------------------PGNGIYINFTVLQTEPIYD 2295
+Q C W ++P N +Y N + + +
Sbjct: 753 HAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY 812
Query: 2296 FI--------------TVWDGPDQN-----------SPQIGQFSGNTALESVYSTSNQIL 2330
+ W GP +P++ S YS ++ +
Sbjct: 813 LLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVY 872
Query: 2331 IKFHSDFTTSGFFVLSYHAYQLRV-------------CQPPPPVPNAEILTED-DEFEIG 2376
+ + F +G V+ H V C PPP PN + F G
Sbjct: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPG 932
Query: 2377 DIIRYQCLPGFTLVGNAILTC 2397
I Y C G+ LVG A+L C
Sbjct: 933 MSILYSCDQGYLLVGEALLLC 953
Score = 80.5 bits (197), Expect = 3e-14
Identities = 156/664 (23%), Positives = 237/664 (35%), Gaps = 164/664 (24%)
Query: 1158 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPN 1216
F G ++ +SC+ GY L G I C G VW+ P+P+C VA C A+ +L P
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG--VWTPPVPQCKVAACEATGRQ---LLTKPQ 483
Query: 1217 YP-LNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---LKIYDGKDKTTH-----LL 1267
+ + + N C G+G +S + QG + ++I K+ T
Sbjct: 484 HQFVRPDVNSSC--------GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN 535
Query: 1268 GAFTGASMR----GLTLSSTSN---QLWLEF------------NSDTEGTDEG-FQLVYT 1307
GA TG+S+ G T++ T N + +EF N GT G L
Sbjct: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
Query: 1308 SFELSHCEDPGIPQFGYKIS--DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
S C I GYKIS + +F T+ + C G+TL GSS ++C WD
Sbjct: 596 SLLAVQCSHVHIAN-GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD--NTWDP 652
Query: 1366 PLPSCIAEC-------GGRFKGESSGRILS---------PGYPFPYDNNLRCMWMIEVDP 1409
+P C C GR G ++ +S PGY + ++ CM
Sbjct: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM-----PS 707
Query: 1410 GNIVSLQFLAFDTEASHDILRVWD-GPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTD 1468
GN W P + + + SL S + +V
Sbjct: 708 GN--------------------WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDG 747
Query: 1469 FYISKSGFAIQFSSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVF 1512
+ + +G A Q C P V +NG G E G+ V +
Sbjct: 748 YQL--TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSY 805
Query: 1513 QCDPGYELQGEERITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNF 1564
+CD G+ L GE+++ C + W SPPV P N G+ L+
Sbjct: 806 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH 862
Query: 1565 PHPYPHSR----DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQ 1619
Y H+ DC+ +N VI + D ++ P IG
Sbjct: 863 -SAYSHNDIVYVDCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPP 912
Query: 1620 DSKLPERIESSSNTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RES 1660
K P + N F S+ Y+ G+ L +A L +
Sbjct: 913 PPKTPNGNHTGGNIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
Query: 1661 CFDPGNIMNGTRLGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
C P + M+G + G++ Y+ G+ VT C+ GY+L+G C WN L
Sbjct: 971 CSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLA 1025
Query: 1717 SCHA 1720
C +
Sbjct: 1026 VCRS 1029
Score = 72.4 bits (176), Expect = 8e-12
Identities = 138/646 (21%), Positives = 228/646 (35%), Gaps = 124/646 (19%)
Query: 1678 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1736
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
Query: 1737 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1792
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
Query: 1793 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1837
+ L + SG + T+ F + T KG + ++ +
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
Query: 1838 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
Query: 1895 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1929
C + C +LTK + + P Y E P+ + +I
Sbjct: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
Query: 1930 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 1983
T P V + H SL+ + G N P G + TSN
Sbjct: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
Query: 1984 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 2040
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 2041 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGF-PGNYPSSLDCTW 2099
G++L+G S I C W+ IP+C C PG G + +
Sbjct: 633 GFTLKGSSQIRCKAD--NTWDPEIPVCEKGCQS----------PPGLHHGRHTGGNTVFF 680
Query: 2100 TINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSL 2159
+ + + ++ ++IH + SG+ S + + SL + +
Sbjct: 681 VSGMTVDYTCDPGYLLVGNKSIHC---MPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
Query: 2160 YFHSDYSQNKQGFHIVYQAYQLQS------------------CPDPRPFRNG---FVIGN 2198
+ Q+ G+ + AYQ+ C P NG ++
Sbjct: 738 ELVNTSCQD--GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
Query: 2199 DFTVGQTISFECFPGYTLIGNSALTCL-----HGVSRNWNHPLPRC 2239
+F G +S+EC G+ L+G L C HG +W+ P P+C
Sbjct: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPSPQC 838
Score = 62.4 bits (150), Expect = 8e-09
Identities = 145/624 (23%), Positives = 214/624 (34%), Gaps = 142/624 (22%)
Query: 989 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 1041
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 1042 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1092
GY P S C V G+GV + + + E P
Sbjct: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
Query: 1093 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1152
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
Query: 1153 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1212
NF + T C+ + GT WS P PRC A + IL
Sbjct: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
Query: 1213 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1257
Y N C++ ++ K I +A+ V + I
Sbjct: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Query: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1317
+G+ + H++ G S++ S + L + T EG V+T + C+
Sbjct: 418 NGQKEDRHMVRFDPGTSIK----YSCNPGYVLVGEESIQCTSEG---VWTP-PVPQCKVA 469
Query: 1318 GIPQFGYKI--SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAEC 1374
G ++ Q F + C GY L GS +C W + C C
Sbjct: 470 ACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ--GTIPWFMEIRLCKEITC 527
Query: 1375 GGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1427
+ G +G L FPY + +PG ++F S+D
Sbjct: 528 PPPPVIYNGAHTGSSLE---DFPYGTTV----TYTCNPGPERGVEFSLIGESTIRCTSND 580
Query: 1428 ILR-VWDGPP---ENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS 1482
R W GP + +L + S I G S DT + SGF ++ SS
Sbjct: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSS 640
Query: 1483 SV---ATACRDPGVPM------------NGTRNGDGR---EPGDTVVFQCDPGYELQGEE 1524
+ A DP +P+ +G G G TV + CDPGY L G +
Sbjct: 641 QIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNK 700
Query: 1525 RITCIQVENRYFWQPSPPVCIAPC 1548
I C+ N W PS P C C
Sbjct: 701 SIHCMPSGN---WSPSAPRCEETC 721
Score = 58.9 bits (141), Expect = 9e-08
Identities = 134/619 (21%), Positives = 214/619 (34%), Gaps = 128/619 (20%)
Query: 1160 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1217
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
Query: 1218 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1277
Y N + V G I S H GD + T SM G
Sbjct: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Query: 1278 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1333
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
Query: 1334 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1379
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
Query: 1380 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1436
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
Query: 1437 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1481
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
Query: 1482 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1538
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
Query: 1539 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1594
PS PVC C +G H + N YV+ S+ S
Sbjct: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
Query: 1595 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1648
+ P + + L+ Q + + SS ++ GSV
Sbjct: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
Query: 1649 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1699
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 1700 TCIMGDDGRPGWNRALPSC 1718
C D R W+ P C
Sbjct: 575 RCTSNDQERGTWSGPAPLC 593
Score = 57.8 bits (138), Expect = 2e-07
Identities = 110/479 (22%), Positives = 162/479 (33%), Gaps = 111/479 (23%)
Query: 1141 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1195
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
Query: 1196 RC-VAECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAG--- 1236
C A C + G + P Y L + C+ + Q A
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 1237 ---------------KGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1281
G +I +++ G ++ D + G S T+
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
Query: 1282 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQ--GHFAGSTIIY 1339
S W G +L S C P I + G +S Q + T+I+
Sbjct: 329 SQKTGTW-------SGPAPRCEL---STSAVQCPHPQILR-GRMVSGQKDRYTYNDTVIF 377
Query: 1340 GCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RF-KGESS 1383
C G+TL GS ++C + W+ P C EC RF G S
Sbjct: 378 ACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSI 435
Query: 1384 GRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGPPE 1437
+PGY + +++C +W V + + + T+ H +R P
Sbjct: 436 KYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----PDV 491
Query: 1438 NDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
N + ++SGS+ E TI + + + K C P V
Sbjct: 492 NSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPVIY 534
Query: 1496 NGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCI-QVENRYFWQPSPPVC 1544
NG G E G TV + C+PG + L GE I C + R W P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 48/286 (16%)
Query: 1646 YTGFHLEYKAKLR---------------ESCFDPGNIMNGTRLGMD---YKLGSTVTYYC 1687
Y+GF L+ +++R + C P + +G G + + G TV Y C
Sbjct: 631 YSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTC 690
Query: 1688 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC-------GSRSTGSEGTVLSPNYPK 1740
D GY+L G ++ C+ + W+ + P C C GS +++ +
Sbjct: 691 DPGYLLVGNKSIHCMPSGN----WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQD 746
Query: 1741 NYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH------DVVEVYDGPTQQSSLLSSLSG 1793
Y + GH Y + E ++ + + +H V + G ++ L +
Sbjct: 747 GYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVS 804
Query: 1794 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG-- 1851
+ L ++ R S G + G Q + T+C + PE + G ++
Sbjct: 805 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--PQCLRSPPVTRCPN-PEVKHGYKLNKT 861
Query: 1852 -NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1896
+ ++ V DCNPG+I++GS IRC T W +PTCI
Sbjct: 862 HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGVPTCI 903
Score = 51.2 bits (121), Expect = 2e-05
Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 59/252 (23%)
Query: 970 CLDPGIPVHGRRYG---HDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHW-WSHPLPT 1022
C P + V+G+ G +F G+ VS+ CD G+ L E+ L C K H WS P P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 1023 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1082
C +R P T PN +V HG + T H+D +
Sbjct: 838 C-------LRSPPVTRC--------PNP-------EVKHGYKLN---KTHSAYSHNDIVY 872
Query: 1083 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1142
+ N F +R+ T G+ + FI C
Sbjct: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKA--FIG--------------------C 910
Query: 1143 EDPGIPQYGSRIGFN---FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1199
P G+ G N F G ++ +SC GY L G + ++C G WS P P C
Sbjct: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHCKE 968
Query: 1200 ECGASATNNEGI 1211
+S + +GI
Sbjct: 969 VNCSSPADMDGI 980
Score = 49.3 bits (116), Expect = 7e-05
Identities = 91/414 (21%), Positives = 146/414 (35%), Gaps = 88/414 (21%)
Query: 635 REGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLS 694
+E F N D + F+C GF L G I C+ +N W IP+ C +P G
Sbjct: 616 KEAPYFYN-DTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV----CEKGCQSPPGL--- 667
Query: 695 PDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFT 752
+ G N T+ G + + + + L + G+ SP +P T
Sbjct: 668 -HHGRHTGGN-----TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-T 720
Query: 753 GAEVPSHLT-----SNSHILRLEFQADHSMSGRGFNITYNTFGHN-----------ECPD 796
V L S ++ Q + ++G + + + C
Sbjct: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
Query: 797 PGIPINARRFG---DNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCG 852
P + +N + G +NF G+ +S C++GF G + + C G WSG P+C
Sbjct: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCL 839
Query: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 912
S P +P E + G+ + T + + D++ V
Sbjct: 840 R------SPPVTRCPNP----------------EVKHGYKLNKTHSAYS---HNDIVYVD 874
Query: 913 DGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLD 972
P + NG++V + TDN+ G + + C
Sbjct: 875 CNPGFIM------NGSRV------------IRCHTDNTWVP-GVPTCIKKAFIG---CPP 912
Query: 973 PGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
P +G G + FS G ++ +SCD GY L E LLC WS P P C
Sbjct: 913 PPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966
Score = 45.8 bits (107), Expect = 8e-04
Identities = 90/440 (20%), Positives = 155/440 (35%), Gaps = 81/440 (18%)
Query: 638 DGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDY 697
D ++ D + F C FGF L G K I C W + P+C C AP P+
Sbjct: 367 DRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC----QAP------PNI 416
Query: 698 PEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG----DSPESPILG-TF 751
G + + + DPG+ I S N + L + +G P+ +
Sbjct: 417 LNGQKEDRH---MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEA 473
Query: 752 TGAEVPSHLTSNSH-ILRLEFQADHSMSGRGFNITYNTFGHNE----------------C 794
TG ++ LT H +R + +S G G+ ++ + + + C
Sbjct: 474 TGRQL---LTKPQHQFVRPDV---NSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 795 PDPGIPINARRFG---DNFQLGSSISVICEEG-----FIKTQGTETITCILMD-GKVMWS 845
P P + N G ++F G++++ C G G TI C D + WS
Sbjct: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587
Query: 846 GLIPKC-----GAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-R 899
G P C C A I P +Y D++ + G ++K + + R
Sbjct: 588 GPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTV----TFKCYSGFTLKGSSQIR 643
Query: 900 FQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLL--FTTDNSRSNNGFK 957
+ + +D P + G + + + N ++ + T D +
Sbjct: 644 CKADNTWD-------PEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLL 696
Query: 958 IHYESVTVNTYSCLDPGIP------VHGRRYGHDFSIGSTVSF---SCDSGYRLSHEEPL 1008
+ +S+ P P H R+ + GS V SC GY+L+
Sbjct: 697 VGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQ 756
Query: 1009 LCE--KNHWWSHPLPTCDAL 1026
+C+ +N W +P C +
Sbjct: 757 MCQDAENGIWFKKIPLCKVI 776
Score = 45.1 bits (105), Expect = 0.001
Identities = 56/247 (22%), Positives = 85/247 (34%), Gaps = 78/247 (31%)
Query: 972 DPGIPV------------HGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 1016
DP IPV HGR G + F G TV ++CD GY L + + C + W
Sbjct: 651 DPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNW 710
Query: 1017 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL-E 1075
S P C+ C VR + + E V+ + G Q H + + +
Sbjct: 711 SPSAPRCEETC-QHVRQSLQELPAGSRVEL----------VNTSCQDGYQLTGHAYQMCQ 759
Query: 1076 DHHDYLLITENGSFTQ--PLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNIT 1133
D ENG + + PL ++ PP I G + A+
Sbjct: 760 D-------AENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE----------------- 795
Query: 1134 FSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG--GRRVWS 1191
NF G+ +++ C G+ L G ++ C G WS
Sbjct: 796 -----------------------NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 832
Query: 1192 APLPRCV 1198
P P+C+
Sbjct: 833 GPSPQCL 839
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 439 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 495
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 903 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 958
Query: 496 WSDHRPVCKVKTCGS 510
WS P CK C S
Sbjct: 959 WSQPAPHCKEVNCSS 973
Score = 44.7 bits (104), Expect = 0.002
Identities = 187/872 (21%), Positives = 282/872 (32%), Gaps = 178/872 (20%)
Query: 793 ECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 849
ECP + N +N G S++ CE G++ G + I C L GK WS + P
Sbjct: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPP 208
Query: 850 KCG-APCGGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSI 893
C A C P+G + P G+ S C + +
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 894 KITFERFQTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLF 945
+ E F + H G +L + GS Y P+ NFI L
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRC 325
Query: 946 TTDNSRSN--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGY 1000
T D+ ++ +G E ++ + C P I + GR ++ TV F+C G+
Sbjct: 326 TVDSQKTGTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 1001 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGY 1043
L + + C W P C+ C VR GT + +PGY
Sbjct: 384 TLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 1044 PEFYPNSLNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT 1097
S+ CT WT V K + + H ++ N S + +L+
Sbjct: 444 VLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLS 502
Query: 1098 GSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF- 1156
GS +Y + + + + + E IT C P + G+ G
Sbjct: 503 GS---------VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSS 542
Query: 1157 --NFGIGDTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAEC 1201
+F G T+T++C+ G + L G S I C R WS P P C +C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 1202 GASATNNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDG 1259
N + P Y + +C ++ I A + V +
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
Query: 1260 KDKTTHLLGAFTGAS----MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1315
H G TG + + G+T+ T D G+ LV + HC
Sbjct: 663 SPPGLH-HGRHTGGNTVFFVSGMTVDYT--------------CDPGYLLV--GNKSIHCM 705
Query: 1316 -----DPGIPQF-----GYKISDQGHFAGSTIIY---GCNPGYTLHGSSLLKCMTGERRA 1362
P P+ + S Q AGS + C GY L G + C E
Sbjct: 706 PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGI 765
Query: 1363 WDYPLPSC-IAECGGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFL 1418
W +P C + C G+ +G + F Y N + E D G L
Sbjct: 766 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAE---NFLYGNEV----SYECDQG-FYLLGEK 817
Query: 1419 AFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHS-TLNIVTIQFDTD--FYISKSG 1475
+ W GP + ++ PE H LN + + Y+ +
Sbjct: 818 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNP 877
Query: 1476 FAIQFSSSVATACRD----PGVPM----------------NGTRNGDG---REPGDTVVF 1512
I S V D PGVP NG G PG ++++
Sbjct: 878 GFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILY 937
Query: 1513 QCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
CD GY L GE + C + W P C
Sbjct: 938 SCDQGYLLVGEALLLC---THEGTWSQPAPHC 966
Score = 43.1 bits (100), Expect = 0.005
Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 153 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMR 206
RFD G I+YSC GY+L G + C + V W PVP C+ AC T R
Sbjct: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGV----WTPPVPQCKVA-ACEATGR 476
Score = 42.4 bits (98), Expect = 0.009
Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 195 C 195
C
Sbjct: 82 C 82
Score = 42.4 bits (98), Expect = 0.009
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 623 SCGDPGTPL-YGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWS-ANIPICI 678
SC +P P Y IR + + D + F C+ F + G KS+ CQ NN W +P C+
Sbjct: 90 SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCV 147
Score = 42.4 bits (98), Expect = 0.009
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 446 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 503 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 838 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 885
Query: 562 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 609
+ G P + + G P I S M + D+
Sbjct: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 945
Query: 610 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 655
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 946 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 1005
Query: 656 LIGEKSIVCQENNQWSANIPIC 677
L G CQ ++QW+ + +C
Sbjct: 1006 LEGSPQSQCQSDHQWNPPLAVC 1027
Score = 41.2 bits (95), Expect = 0.019
Identities = 60/256 (23%), Positives = 100/256 (39%), Gaps = 33/256 (12%)
Query: 446 CPDPGEPENGKRIGS---DFSLGSTVQFSCDE------DYVLQGAKSITCQRIAEVFAAW 496
CP P NG GS DF G+TV ++C+ ++ L G +I C + W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 497 SDHRPVCKVKTCG---SNLQGPSG-TFTSPNFPFQYDSNA--QCVWVITAVNTNKVIQIN 550
S P+CK+ S++ +G + P+ Y+ +C T ++++
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
Query: 551 FEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGS----FVPDLIVSMSSQMWLHLQTDES 606
+D EI + + G P TG FV + V + L ++S
Sbjct: 647 DNTWDPEI-----PVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKS 701
Query: 607 V---GSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIV 663
+ S + + E E+C L + G S +++ CQ G++L G +
Sbjct: 702 IHCMPSGNWSPSAPRCE-ETCQHVRQSLQELPAG---SRVELVNTSCQDGYQLTGHAYQM 757
Query: 664 CQ--ENNQWSANIPIC 677
CQ EN W IP+C
Sbjct: 758 CQDAENGIWFKKIPLC 773
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 9/71 (12%)
Query: 446 CPDPGEPENGKRIGSDF---SLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAW 496
CP P NG+ IG+ S GS V ++CD D ++L G ++ C ++ W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 497 SDHRPVCKVKT 507
S P C++ T
Sbjct: 336 SGPAPRCELST 346
Score = 38.9 bits (89), Expect = 0.095
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 1660 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1718 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1764
C P G + G S Y SV C + ++ V+ Q
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 1765 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1823
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
Query: 1824 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1874
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
Query: 1875 AIRCETVPNSLAQWNDSLPTC 1895
+ RC +A W +P C
Sbjct: 253 SSRCVIAGQGVA-WT-KMPVC 271
Score = 37.7 bits (86), Expect = 0.21
Identities = 74/300 (24%), Positives = 108/300 (36%), Gaps = 61/300 (20%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C G NGK + +G T F CDE Y LQG S C IA AW+ PVC+
Sbjct: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCE 272
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTL 563
C S +G + +N ++T + + +NF + IG TL
Sbjct: 273 EIFCPSPPPILNGRHIGNSL-----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTL 323
Query: 564 TIG-DGGEVGD-----PRTVL----------QVLTGSFVPDLIVSMSSQMWLHLQTDESV 607
D + G PR L Q+L G V S Q + D +
Sbjct: 324 RCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVI 376
Query: 608 GSVGFKVNYKEIEKESCGDPGT--PLYGIREGD----------GFSNRDVLRFE------ 649
+ F K ++ C GT P + E + +R ++RF+
Sbjct: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
Query: 650 --CQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 702
C G+ L+GE+SI C W+ +P C + C + T P + PD G
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
Score = 35.8 bits (81), Expect = 0.80
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 969 SCLDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPT 1022
SC P ++GR Y ++G+ + +SC +RL E+ LLC + + W P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1023 CD 1024
C+
Sbjct: 82 CE 83
Score = 35.8 bits (81), Expect = 0.80
Identities = 56/279 (20%), Positives = 105/279 (37%), Gaps = 63/279 (22%)
Query: 1134 FSEYNLEPCEDPGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS- 1191
F++Y+ C +P +P Y R + GD++TF+C + + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGP 140
Query: 1192 APLPRCVA----ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1247
LP CV+ EC P P+ + +H + G + S + +
Sbjct: 141 TRLPTCVSVFPLEC-------------PALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
Query: 1248 LAQGD--VLKIYDGK---------DKTTHLLGAFTGASMR-------GLTLSSTSNQLW- 1288
L G+ + + GK + LG F ++ G+T + ++ +
Sbjct: 188 LLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247
Query: 1289 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP---------QFGYKISDQGHFAGSTIIY 1339
L+ + G + +T + CE+ P G +++ + GS + Y
Sbjct: 248 LQGPPSSRCVIAGQGVAWTKMPV--CEEIFCPSPPPILNGRHIGNSLANVSY--GSIVTY 303
Query: 1340 GCNP------GYTLHGSSLLKCMTGERR--AWDYPLPSC 1370
C+P + L G S L+C ++ W P P C
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342
Score = 35.8 bits (81), Expect = 0.80
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 138 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 965
Query: 195 CR 196
C+
Sbjct: 966 CK 967
Score = 35.8 bits (81), Expect = 0.80
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 1028
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 990 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
Score = 35.0 bits (79), Expect = 1.4
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 446 CPDPGEPENG----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 501
CP NG + +GS + G +V +SC+ Y+L G K I C + WS P
Sbjct: 154 CPALPMIHNGHHTSENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPP 208
Query: 502 VCKVKTCGSNLQGPSGTFTSP 522
C+ C S + P+G P
Sbjct: 209 TCEEARCKSLGRFPNGKVKEP 229
Score = 35.0 bits (79), Expect = 1.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 648 FECQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSNFTAPMGTVLSP 695
+ C+ G+ L+GEK I C + +WSA P C C S P G V P
Sbjct: 181 YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEP 229
Score = 34.7 bits (78), Expect = 1.8
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
F G+++ Y C G+ L G +L C ++S SW P P C
Sbjct: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 838
Score = 33.5 bits (75), Expect = 4.0
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 13/88 (14%)
Query: 624 CGDPGTPLYGIREG---DGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANIPI 676
C P + G G + F + + +EC GF L+GEK + C+ +++ WS P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 677 CIFPCLSNFTAPMGTVLSPDYPEGYGNN 704
C+ + P+ +P+ GY N
Sbjct: 838 CL------RSPPVTRCPNPEVKHGYKLN 859
Score = 33.1 bits (74), Expect = 5.2
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 131 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 1022
Query: 191 PVPICRA 197
P+ +CR+
Sbjct: 1023 PLAVCRS 1029
Score = 32.3 bits (72), Expect = 8.9
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 136 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 183
SSC P VP + G T + GD + ++C T + ++G+ + C AN++
Sbjct: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM 137
Score = 32.3 bits (72), Expect = 8.9
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 446 CPDPGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQ 487
CP+P P K GS + G +V F+C ++ + G KS+ CQ
Sbjct: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 345 bits (885), Expect = 5e-94
Identities = 284/979 (29%), Positives = 415/979 (42%), Gaps = 106/979 (10%)
Query: 2529 CSTPESPPHGYI-ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
C +P +G I T + +V+R++C FRL+G+ S +C WD P P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2588 QAI----SCGIPKAPTNGGIL-TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2642
+ SC P P I +T Y G VT+ C + ++ + + CQ++ W
Sbjct: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK--SVWCQANNMW-G 139
Query: 2643 HNKTPRCVVV---TCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIEC 2699
+ P CV V CP++ ++ +G N V +SC+ GY +G I C
Sbjct: 140 PTRLPTCVSVFPLECPALP--MIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINC 197
Query: 2700 LPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2758
L +G WS P C+ C L PNG K G TA F CD G+ L G
Sbjct: 198 LSSGKWS--AVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 2759 CLSSG---LWSESETRCLAGHCGIPELIVNGQVIGE---NYGYRDTVVYQCNP------G 2806
C+ +G W++ C C P I+NG+ IG N Y V Y C+P
Sbjct: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2807 FRLIGSSVRIC----QQDHNWSGQLPSC----VPVSCGHP----GSPIYGRTSGNGFNFN 2854
F LIG S C Q+ WSG P C V C HP G + G+ + + +N
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQK--DRYTYN 372
Query: 2855 DVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2914
D V F+C G+ ++G + +C A W P+C+ C P N ++E + F
Sbjct: 373 DTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDR-HMVRFD 430
Query: 2915 YGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF- 2973
GT + Y CNPGY L G + C G W P+P+C + C G +L+ ++ F
Sbjct: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG---RQLLTKPQHQFV 487
Query: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQES--- 3030
V+ SC L G + CQ W C TC P +G+ S
Sbjct: 488 RPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCK---EITCPPPPVIYNGAHTGSSLE 544
Query: 3031 NFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECK----AVQCGN 3076
+F +TV Y C+ G + L G C +N G+W+G P CK AVQC +
Sbjct: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
Query: 3077 PGTTANGKVFRIDGTT----FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIIS 3132
ANG ++I G ++ +V + C G+ L G S +C A+ TW +P C +
Sbjct: 605 V-HIANG--YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKET 661
Query: 3133 CGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTC--TINGTWSGVMPTCRA 3190
C L G + V+ CQ GY +L G + C NG W +P C+
Sbjct: 662 CQHVRQSLQELPAGSRV---ELVNTSCQDGY--QLTGHAYQMCQDAENGIWFKKIPLCKV 716
Query: 3191 VTCPTPPQISNGRLEG---TNFDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEV 3243
+ C PP I NG+ G NF +G +SY C G+ L L C G+G+WSG
Sbjct: 717 IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 776
Query: 3244 PQCLPK----FCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTW 3297
PQCL C +P + K + ++ + V CN FI+ GS C D TW
Sbjct: 777 PQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTW 836
Query: 3298 SGSSPHCIEPTQTSCENPGVPRHGSQNNTFG----FQVGSVVQFHCKKGHLLQGSTTRTC 3353
P CI+ C P P+ + N+T G F G + + C +G+LL G C
Sbjct: 837 VPGVPTCIKKAFIGCPPP--PKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC 894
Query: 3354 LPDLTWSGIQPECIPHSCKQPE--TPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR 3411
+ TWS P C +C P + + +G + C+ G+ L G + +
Sbjct: 895 THEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQ 954
Query: 3412 VCRSDNTWTGKVPICEAGS 3430
C+SD+ W + +C + S
Sbjct: 955 -CQSDHQWNPPLAVCRSRS 972
Score = 312 bits (800), Expect = 3e-84
Identities = 258/925 (27%), Positives = 389/925 (42%), Gaps = 114/925 (12%)
Query: 2585 PACQAISCGIPKAPTNGGI--LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQS--DGTW 2640
P ISCG P NG I +T VGT + Y C+ +RL ++ + + DGTW
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 2641 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL 2700
P+C S + G ++I + Y + V F+C + G S+ C
Sbjct: 76 DK--PAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 2701 PNGTWSWRNERPYCQII---SCGELPTPPNGNKIGTQTSYGSTA-----IFTCDLGFMLV 2752
N W P C + C LP NG+ T + GS A ++C+ G++LV
Sbjct: 134 ANNMWG-PTRLPTCVSVFPLECPALPMIHNGHH--TSENVGSIAPGLSVTYSCESGYLLV 190
Query: 2753 GSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQV-------IGENYGYRDTVVYQCNP 2805
G + CLSSG WS C C NG+V +G T + C+
Sbjct: 191 GEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV------TANFFCDE 244
Query: 2806 GFRLIG---SSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGF---NFNDVVTF 2859
G+RL G S I Q W+ ++P C + C P + GR GN ++ +VT+
Sbjct: 245 GYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTY 303
Query: 2860 SCN------IGYLMQGPTKAQCQANRQ----WSHPPPMCKV----VNCSDPGIPANSKRE 2905
+C+ + +++ G + +C + Q WS P P C++ V C P I R
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRG--RM 361
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAV 2965
+ +TY V + C G+ L GS + C G W+ P C +C PPN +
Sbjct: 362 VSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC---QAPPN-I 416
Query: 2966 LSGEK-------YTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGD 3018
L+G+K + G+++ YSC L+G+ S C G W+ P C A G
Sbjct: 417 LNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR 476
Query: 3019 PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG 3078
++ + F + V +C GY L GS + C W CK + C P
Sbjct: 477 QLL----TKPQHQF-VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPP 531
Query: 3079 TTANG--KVFRIDGTTFSSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLP 3126
NG ++ + ++V Y+C G + L G S +CT+N GTWSG P
Sbjct: 532 VIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAP 591
Query: 3127 NCTI----ISCGDPGIPANGLRYGD---DYVVGQNVSYMCQPGYTMELNGSRIRTCTING 3179
C + + C I ANG + Y V++ C G+T L GS C +
Sbjct: 592 LCKLSLLAVQCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYSGFT--LKGSSQIRCKADN 648
Query: 3180 TWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTC--VGNG 3237
TW +P C TC Q G+ + ++ C GY+L+ A C NG
Sbjct: 649 TWDPEIPVCEKETCQHVRQSLQELPAGSRVE---LVNTSCQDGYQLTGHAYQMCQDAENG 705
Query: 3238 TWSGEVPQCLPKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQAD 3294
W ++P C C P + GK G ++F+Y +EVS+ C+ F L+G C++D
Sbjct: 706 IWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSD 765
Query: 3295 ----GTWSGSSPHCI-EPTQTSCENPGVPRHGSQNNT--FGFQVGSVVQFHCKKGHLLQG 3347
G+WSG SP C+ P T C NP V +HG + N + +V C G ++ G
Sbjct: 766 SKGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG 824
Query: 3348 STTRTCLPDLTWSGIQPECIPHS---CKQPETPAHANVVGMDLP--SHGYTLIYTCQPGF 3402
S C D TW P CI + C P + N G ++ S G +++Y+C G+
Sbjct: 825 SRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGY 884
Query: 3403 FLAGGTEHRVCRSDNTWTGKVPICE 3427
L G +C + TW+ P C+
Sbjct: 885 LLV-GEALLLCTHEGTWSQPAPHCK 908
Score = 249 bits (635), Expect = 5e-65
Identities = 245/905 (27%), Positives = 368/905 (40%), Gaps = 157/905 (17%)
Query: 2355 CQPPPPVPNAEILTED-DEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
C P + N +E+ G + Y C G+ LVG I+ C + PP C+
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCE 211
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2473
E R S G +PN ++ KE +L+
Sbjct: 212 ------EARCKSLG---------RFPNGKV-----------------------KEPPILR 233
Query: 2474 VYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPE 2533
V N L G SS I G + W+ + +C +P
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQG----VAWTKMPVCEE---------IFCPSPP 280
Query: 2534 SPPHGYIISQTGGQLN--SVVRWACDR------GFRLVGKSSAVCRKSSYGYHAWDAPVP 2585
+G I + ++ S+V + CD F L+G+S+ C S W P P
Sbjct: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
Query: 2586 ACQ----AISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLS-SKELTTAVCQSD 2637
C+ A+ C P+ G +++ Y V + C G+ L SK++ C +
Sbjct: 341 RCELSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR---CNAQ 396
Query: 2638 GTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASI 2697
GTW P C C + + + +G+ + ++ T + +SC+PGY +G SI
Sbjct: 397 GTWEP--SAPVCEK-ECQAPPNIL--NGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESI 451
Query: 2698 ECLPNGTWSWRNERPYCQIISCG----ELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVG 2753
+C G W+ P C++ +C +L T P + + +C G+ L G
Sbjct: 452 QCTSEGVWT--PPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSG 503
Query: 2754 SAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIG---ENYGYRDTVVYQCNPG---- 2806
S +EC + W C C P +I NG G E++ Y TV Y CNPG
Sbjct: 504 SVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERG 563
Query: 2807 --FRLIGSSVRIC----QQDHNWSGQLPSC----VPVSCGHP----GSPIYGRTSGNGFN 2852
F LIG S C Q+ WSG P C + V C H G I G+ + +
Sbjct: 564 VEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP--YF 621
Query: 2853 FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNC-----SDPGIPANSKRESK 2907
+ND VTF C G+ ++G ++ +C+A+ W P+C+ C S +PA S+ E
Sbjct: 622 YNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVE-- 679
Query: 2908 IEHGNFTYGTVVFYDCNPGYFLFGSSVLICQP--NGQWDKPLPECIMIDCGHPGVPPNAV 2965
+V C GY L G + +CQ NG W K +P C +I C P V N
Sbjct: 680 ----------LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGK 729
Query: 2966 LSG---EKYTFGSTVHYSCTGKRSLLGQSSRTCQLN----GHWSGSQPHCSGDATGT-CG 3017
+G E + +G+ V Y C LLG+ C+ + G WSG P C T C
Sbjct: 730 HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP 789
Query: 3018 DPGTPGHG---SRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC--KA- 3071
+P HG ++ S + V C+ G+I++GS C + +W P C KA
Sbjct: 790 NPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAF 848
Query: 3072 VQCGNPGTTANGKVFRIDGTTFSS--SVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3129
+ C P T NG + FS S++YSC +GY+L G ++ CT GTWS P+C
Sbjct: 849 IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 908
Query: 3130 IISCGDP----GIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVM 3185
++C P GI GL Y G V+ C+ GY +E GS C + W+ +
Sbjct: 909 EVNCSSPADMDGI-QKGLEPRKMYQYGAVVTLECEDGYMLE--GSPQSQCQSDHQWNPPL 965
Query: 3186 PTCRA 3190
CR+
Sbjct: 966 AVCRS 970
Score = 196 bits (499), Expect = 3e-49
Identities = 152/579 (26%), Positives = 240/579 (41%), Gaps = 89/579 (15%)
Query: 2552 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDY--L 2609
++++C+ G+ LVG+ S C W PVP C+ +C T +LT
Sbjct: 435 IKYSCNPGYVLVGEESIQCTSEG----VWTPPVPQCKVAAC----EATGRQLLTKPQHQF 486
Query: 2610 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRI 2669
V V C +GY+LS CQ W + C +TCP I
Sbjct: 487 VRPDVNSSCGEGYKLSGSVYQE--CQGTIPWFMEIRL--CKEITCPPPPV---------I 533
Query: 2670 VNGSH-------YEYKTKVVFSCDPG------YHGLGPASIECLPN----GTWSWRNERP 2712
NG+H + Y T V ++C+PG + +G ++I C N GTWS P
Sbjct: 534 YNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS--GPAP 591
Query: 2713 YCQI----ISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLGFMLVGSAVRECLSSGLW 2765
C++ + C + NG KI + + Y T F C GF L GS+ C + W
Sbjct: 592 LCKLSLLAVQCSHVHIA-NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTW 650
Query: 2766 SESETRCLAGHC-----GIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD 2820
C C + EL +V + V C G++L G + ++CQ
Sbjct: 651 DPEIPVCEKETCQHVRQSLQELPAGSRV--------ELVNTSCQDGYQLTGHAYQMCQDA 702
Query: 2821 HN--WSGQLPSCVPVSCGHPGSPIYGRTSG---NGFNFNDVVTFSCNIGYLMQGPTKAQC 2875
N W ++P C + C P + G+ +G F + + V++ C+ G+ + G K QC
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 762
Query: 2876 QANRQ----WSHPPPMC----KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGY 2927
+++ + WS P P C V C +P + K H +++ +V+ DCNPG+
Sbjct: 763 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT--HSAYSHNDIVYVDCNPGF 820
Query: 2928 FLFGSSVLICQPNGQWDKPLPECI---MIDCGHPGVPPNAVLSG---EKYTFGSTVHYSC 2981
+ GS V+ C + W +P CI I C P PN +G +++ G ++ YSC
Sbjct: 821 IMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSC 880
Query: 2982 TGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYA 3041
L+G++ C G WS PHC + D G ++ + V
Sbjct: 881 DQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLE 940
Query: 3042 CDTGYILHGSEERTCLANGSWTGRQPECKA-----VQCG 3075
C+ GY+L GS + C ++ W C++ V CG
Sbjct: 941 CEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 117 bits (294), Expect = 2e-25
Identities = 228/1044 (21%), Positives = 366/1044 (35%), Gaps = 181/1044 (17%)
Query: 1825 FVYQAVPRTSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1882
F+ P C S P GR AVG+ + + C+ + L G ++ C T
Sbjct: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
Query: 1883 NSLAQWNDSLPTC------------IVPCG----GILTKRKGTILSPGYPEPYDNNLN-C 1925
W+ P C IVP G G R G ++ + N N
Sbjct: 70 KVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKS 129
Query: 1926 VWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYS-GTTIPHLLNSTSNN 1984
VW ++ +L G + + +GS + G ++ + S +
Sbjct: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTY---SCESG 186
Query: 1985 LYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSG------IKIGDRYMVGDVVSFQC 2038
L + I+ ++G +++A+ +C E + S G +K VG +F C
Sbjct: 187 YLLVGEKIINCLSSG---KWSAVP-PTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFC 242
Query: 2039 DQGYSLQGHSHITCM-PGPVRRWNYPIPICLAQ-CGGAMSDFSGVILSPGFPGNYPSSLD 2096
D+GY LQG C+ G W +P+C C +G + S+
Sbjct: 243 DEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI- 300
Query: 2097 CTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHE 2156
T+T + GV+ + ST L S +T T SGP P ST+
Sbjct: 301 VTYTCDPDPEEGVNFILIGEST------LRCTVDSQKTGT----WSGPA-PRCELSTS-- 347
Query: 2157 TSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND--FTVGQTISFECFPGY 2214
CP P+ R V G +T T+ F C G+
Sbjct: 348 ------------------------AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 2215 TLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNG-------TIYSPGYPDEY---P 2264
TL G+ + C W P CE C +NG + PG +Y P
Sbjct: 384 TLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 2265 NF-----------QDCFWLVRVPPGNGIYINFT--VLQTEPIYDFITVWDGPDQNSPQIG 2311
+ + W VP T L T+P + F+ PD NS G
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----PDVNS-SCG 496
Query: 2312 QFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQ----PPPPV--PNAE 2365
+ G SVY + F ++R+C+ PPPPV A
Sbjct: 497 E--GYKLSGSVYQECQGTIPWF----------------MEIRLCKEITCPPPPVIYNGAH 538
Query: 2366 ILTEDDEFEIGDIIRYQCLPG------FTLVGNAILTCRLG--ERLQMDGAPPVCQVLCP 2417
+ ++F G + Y C PG F+L+G + + C ER G P+C++
Sbjct: 539 TGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL--- 595
Query: 2418 ANELRLDSTGVILSPGYPDS--------YPNLQMCAWSISVEKGYNITMFVEFFQTEKEF 2469
+ L + + V ++ GY S + +S KG + + E
Sbjct: 596 -SLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEI 654
Query: 2470 DVLQVYDGPNIQSPVLISLSGDYSSAFNITS------NGHEVFLQWSADHGNNKKGFRIR 2523
V + +++ + +G N + GH + A++G K +
Sbjct: 655 PVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 714
Query: 2524 YIAFYCSTPESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2581
+ +C P +G + V + CD+GF L+G+ CR S G+ +W
Sbjct: 715 KV-IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773
Query: 2582 APVPAC----QAISCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQ 2635
P P C C P+ + T Y V CN G+ ++ + C
Sbjct: 774 GPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIR--CH 831
Query: 2636 SDGTWSNHNKTPRCV---VVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGL 2692
+D TW P C+ + CP +G N + + +++SCD GY +
Sbjct: 832 TDNTWV--PGVPTCIKKAFIGCPPPPK--TPNGNHTGGNIARFSPGMSILYSCDQGYLLV 887
Query: 2693 GPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT----SYGSTAIFTCDLG 2748
G A + C GTWS P+C+ ++C P +G + G + YG+ C+ G
Sbjct: 888 GEALLLCTHEGTWS--QPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDG 944
Query: 2749 FMLVGSAVRECLSSGLWSESETRC 2772
+ML GS +C S W+ C
Sbjct: 945 YMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 99.0 bits (245), Expect = 8e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 3184 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3237
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 3238 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3292
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 3293 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3347
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 3348 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3407
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 3408 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3441
R + WT K+P+CE +I P P L
Sbjct: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
Score = 81.6 bits (200), Expect = 1e-14
Identities = 193/878 (21%), Positives = 300/878 (34%), Gaps = 183/878 (20%)
Query: 1141 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1195
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
Query: 1196 RCV-AECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAGKGI 1239
C A C + G + P Y L + C+ + Q A +
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 1240 NISARTF------------------HLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1281
+ F +++ G ++ D + G S T+
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
Query: 1282 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQG--HFAGSTI 1337
S W G +L ++ + H PQ G +S Q + T+
Sbjct: 329 SQKTGTW-------SGPAPRCELSTSAVQCPH------PQILRGRMVSGQKDRYTYNDTV 375
Query: 1338 IYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RFK-GE 1381
I+ C G+TL GS ++C + W+ P C EC RF G
Sbjct: 376 IFACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGT 433
Query: 1382 SSGRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGP 1435
S +PGY + +++C +W V + + + T+ H +R P
Sbjct: 434 SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----P 489
Query: 1436 PENDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGV 1493
N + ++SGS+ E TI + + + K C P V
Sbjct: 490 DVNSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPV 532
Query: 1494 PMNGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCIQVEN-RYFWQPSPPV 1543
NG G E G TV + C+PG + L GE I C + R W P+
Sbjct: 533 IYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPL 592
Query: 1544 C----IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1599
C +A ++ ++G+ +S PY ++ D V + F+++ +
Sbjct: 593 CKLSLLAVQCSHVHIANGYKISGK-EAPYFYN-----------DTVTFKCYSGFTLKGSS 640
Query: 1600 DFLYIYDGP-DSNSPLIG---------SFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1649
D D P+ S Q+ R+E + + ++ G
Sbjct: 641 QIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQ 700
Query: 1650 HLEYKAKLRE-------SCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAGYVLQGYSTL 1699
E ++ C P I+NG GM ++ G+ V+Y CD G+ L G L
Sbjct: 701 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 760
Query: 1700 TCIMGDDGRPGWNRALPSC-HAPCGSRSTGSEGTVLSPNYPKN---YSVGHNCVYSIAVP 1755
C G W+ P C +P +R E + Y N + HN + +
Sbjct: 761 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE---VKHGYKLNKTHSAYSHNDIVYVDCN 817
Query: 1756 KEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLL-------SSLSGSHSGESLP-LSSGNQ 1807
F++ G V D V PT + +G+H+G ++ S G
Sbjct: 818 PGFIMNGSRVI--RCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMS 875
Query: 1808 ITIR----FTSVGPITAKGFH--FVYQAVPRTSSTQCSSVPEPRFGRRIGNE----FAVG 1857
I + VG H Q P CSS P G + G E + G
Sbjct: 876 ILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYG 934
Query: 1858 SSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1895
+ V +C GY+L GS +C+ S QWN L C
Sbjct: 935 AVVTLECEDGYMLEGSPQSQCQ----SDHQWNPPLAVC 968
Score = 68.6 bits (166), Expect = 1e-10
Identities = 170/817 (20%), Positives = 277/817 (33%), Gaps = 159/817 (19%)
Query: 1160 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1217
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
Query: 1218 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1277
Y N + V G I S H GD + T SM G
Sbjct: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Query: 1278 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1333
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
Query: 1334 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1379
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
Query: 1380 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1436
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
Query: 1437 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1481
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
Query: 1482 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1538
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
Query: 1539 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1594
PS PVC C +G H + N YV+ S+ S
Sbjct: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
Query: 1595 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1648
+ P + + L+ Q + + SS ++ GSV
Sbjct: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
Query: 1649 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1699
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 1700 TCIMGDDGRPGWNRALPSC------------HAPCGSRSTGSEGTVLSPNYPKNYSVGHN 1747
C D R W+ P C H G + +G E Y N +V
Sbjct: 575 RCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP-----YFYNDTVTFK 629
Query: 1748 CVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPL----- 1802
C + + + + + V + T Q + SL +G + L
Sbjct: 630 CYSGFTLKGSSQIRCK---ADNTWDPEIPVCEKETCQ-HVRQSLQELPAGSRVELVNTSC 685
Query: 1803 SSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSS 1859
G Q+T + G F + +P C P G+ G F G+
Sbjct: 686 QDGYQLTGHAYQMCQDAENGIWF--KKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 743
Query: 1860 VLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1896
V ++C+ G+ L G ++C + W+ P C+
Sbjct: 744 VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 780
Score = 62.8 bits (151), Expect = 6e-09
Identities = 102/447 (22%), Positives = 162/447 (36%), Gaps = 79/447 (17%)
Query: 1678 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1736
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
Query: 1737 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1792
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
Query: 1793 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1837
+ L + SG + T+ F + T KG + ++ +
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
Query: 1838 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
Query: 1895 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1929
C + C +LTK + + P Y E P+ + +I
Sbjct: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
Query: 1930 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 1983
T P V + H SL+ + G N P G + TSN
Sbjct: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
Query: 1984 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 2040
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 2041 GYSLQGHSHITCMPGPVRRWNYPIPIC 2067
G++L+G S I C W+ IP+C
Sbjct: 633 GFTLKGSSQIRCKAD--NTWDPEIPVC 657
Score = 59.7 bits (143), Expect = 5e-08
Identities = 142/694 (20%), Positives = 232/694 (33%), Gaps = 178/694 (25%)
Query: 446 CPDPGEPENGKRIGSDF---SLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAW 496
CP P NG+ IG+ S GS V ++CD D ++L G ++ C ++ W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 497 SDHRPVCKVKTC-----------GSNLQGPSGTFTSPN-------FPF------QYDSNA 532
S P C++ T G + G +T + F F Q NA
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 533 QCVWVITAVNTNKVIQ-----INFEEFD--------------------LEIGYDTLTIGD 567
Q W +A K Q +N ++ D + +G +++
Sbjct: 396 QGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTS 455
Query: 568 GGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN---YKEIE---- 620
G P +V +++ ++ + S G G+K++ Y+E +
Sbjct: 456 EGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE-GYKLSGSVYQECQGTIP 514
Query: 621 --------KE-SCGDPGTPLYGIREG---DGFSNRDVLRFECQFG------FELIGEKSI 662
KE +C P G G + F + + C G F LIGE +I
Sbjct: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 663 VCQENNQ----WSANIPIC-----IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIIS 713
C N+Q WS P+C C A + + P Y + +
Sbjct: 575 RCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVT------- 627
Query: 714 DPGSRIHLSFNDFDLESQFDFLAVKDGD-SPESPILGTFTGAEVPSHLT-----SNSHIL 767
++ F L+ D PE P+ T V L S ++
Sbjct: 628 ------FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELV 681
Query: 768 RLEFQADHSMSGRGFNITYNTFGH-----------NECPDPGIPINARRFG---DNFQLG 813
Q + ++G + + + C P + +N + G +NF G
Sbjct: 682 NTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYG 741
Query: 814 SSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWP 872
+ +S C++GF G + + C G WSG P+C S P +P
Sbjct: 742 NEVSYECDQGFY-LLGEKKLQCRSDSKGHGSWSGPSPQCLR------SPPVTRCPNP--- 791
Query: 873 GYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQ 932
E + G+ + T + + D++ V P + NG++V
Sbjct: 792 -------------EVKHGYKLNKTHSAYS---HNDIVYVDCNPGFI------MNGSRV-- 827
Query: 933 FLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIG 989
+ TDN+ G + + C P +G G + FS G
Sbjct: 828 ----------IRCHTDNTWV-PGVPTCIKKAFI---GCPPPPKTPNGNHTGGNIARFSPG 873
Query: 990 STVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
++ +SCD GY L E LLC WS P P C
Sbjct: 874 MSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 907
Score = 59.3 bits (142), Expect = 7e-08
Identities = 188/892 (21%), Positives = 295/892 (33%), Gaps = 257/892 (28%)
Query: 989 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 1041
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 1042 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1092
GY P S C V G+GV + + + E P
Sbjct: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
Query: 1093 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1152
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
Query: 1153 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1212
NF + T C+ + GT WS P PRC A + IL
Sbjct: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
Query: 1213 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1257
Y N C++ ++ K I +A+ V + I
Sbjct: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Query: 1258 DGKDKTTHLLGAFTGASMR-----------GLTLSSTSNQLWL----------------- 1289
+G+ + H++ G S++ ++ TS +W
Sbjct: 418 NGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQ 477
Query: 1290 ------------EFNS--------------DTEGTDEGFQLVYTSFELSHCEDPGIPQFG 1323
+ NS + +GT F + E++ P I
Sbjct: 478 LLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGA 537
Query: 1324 YKISDQGHFA-GSTIIYGCNPG------YTLHGSSLLKCMTG--ERRAWDYPLPSC---- 1370
+ S F G+T+ Y CNPG ++L G S ++C + ER W P P C
Sbjct: 538 HTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSL 597
Query: 1371 IAECGGRFKGESSGRILSPGYPFPYDNNL--RCMWMIEVDPGNIVSLQFLAFDTEASHDI 1428
+A + +I P+ Y++ + +C + F + S I
Sbjct: 598 LAVQCSHVHIANGYKISGKEAPYFYNDTVTFKC---------------YSGFTLKGSSQI 642
Query: 1429 L----RVWDGPPENDMLLKE----ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1480
WD PE + KE + SL S + +V + + +G A Q
Sbjct: 643 RCKADNTWD--PEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQL--TGHAYQM 698
Query: 1481 SSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVFQCDPGYELQGEE 1524
C P V +NG G E G+ V ++CD G+ L GE+
Sbjct: 699 CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK 758
Query: 1525 RITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR---- 1572
++ C + W SPPV P N G+ L+ Y H+
Sbjct: 759 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH-SAYSHNDIVYV 814
Query: 1573 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQDSKLPERIESSS 1631
DC+ +N VI + D ++ P IG K P +
Sbjct: 815 DCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGG 865
Query: 1632 NTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RESCFDPGNIMNGTR 1672
N F S+ Y+ G+ L +A L +C P + M+G +
Sbjct: 866 NIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQ 922
Query: 1673 LGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1720
G++ Y+ G+ VT C+ GY+L+G C WN L C +
Sbjct: 923 KGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLAVCRS 970
Score = 48.1 bits (113), Expect = 2e-04
Identities = 137/667 (20%), Positives = 225/667 (33%), Gaps = 127/667 (19%)
Query: 793 ECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 849
ECP + N +N G S++ CE G++ G + I C L GK WS + P
Sbjct: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPP 208
Query: 850 KCG-APCGGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSI 893
C A C P+G + P G+ S C + +
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 894 KITFERFQTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLF 945
+ E F + H G +L + GS Y P+ NFI L
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRC 325
Query: 946 TTDNSRSN--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGY 1000
T D+ ++ +G E ++ + C P I + GR ++ TV F+C G+
Sbjct: 326 TVDSQKTGTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 1001 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGY 1043
L + + C W P C+ C VR GT + +PGY
Sbjct: 384 TLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 1044 PEFYPNSLNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT 1097
S+ CT WT V K + + H ++ N S + +L+
Sbjct: 444 VLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLS 502
Query: 1098 GSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF- 1156
GS +Y + + + + + E IT C P + G+ G
Sbjct: 503 GS---------VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSS 542
Query: 1157 --NFGIGDTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAEC 1201
+F G T+T++C+ G + L G S I C R WS P P C +C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 1202 GASATNNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDG 1259
N + P Y + +C ++ I A + V +
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCE---- 658
Query: 1260 KDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS----------- 1308
K+ H+ S++ L S + + T +Q+ +
Sbjct: 659 KETCQHV-----RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPL 713
Query: 1309 FELSHCEDPGIPQFGYK--ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGER--RAWD 1364
++ HC P + G + + G+ + Y C+ G+ L G L+C + + +W
Sbjct: 714 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773
Query: 1365 YPLPSCI 1371
P P C+
Sbjct: 774 GPSPQCL 780
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 439 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 495
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 844 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 899
Query: 496 WSDHRPVCKVKTCGS 510
WS P CK C S
Sbjct: 900 WSQPAPHCKEVNCSS 914
Score = 43.9 bits (102), Expect = 0.003
Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 34/252 (13%)
Query: 1666 NIMNGTRLG---MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC 1722
+I NG ++ Y TVT+ C +G+ L+G S + C + W+ +P C
Sbjct: 606 HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT----WDPEIPVCEKET 661
Query: 1723 GSR--------STGSEGTVLSPNYPKNYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLHD 1773
GS +++ + Y + GH Y + E ++ + + +H
Sbjct: 662 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHC 719
Query: 1774 ------VVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
V + G ++ L + + L ++ R S G + G
Sbjct: 720 HPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--P 777
Query: 1828 QAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSS---VLFDCNPGYILHGSIAIRCETVPNS 1884
Q + T+C + PE + G ++ + S V DCNPG+I++GS IRC T
Sbjct: 778 QCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT- 835
Query: 1885 LAQWNDSLPTCI 1896
W +PTCI
Sbjct: 836 ---WVPGVPTCI 844
Score = 43.1 bits (100), Expect = 0.005
Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 153 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMR 206
RFD G I+YSC GY+L G + C + V W PVP C+ AC T R
Sbjct: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGV----WTPPVPQCKVA-ACEATGR 476
Score = 42.4 bits (98), Expect = 0.009
Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 195 C 195
C
Sbjct: 82 C 82
Score = 42.4 bits (98), Expect = 0.009
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 623 SCGDPGTPL-YGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWS-ANIPICI 678
SC +P P Y IR + + D + F C+ F + G KS+ CQ NN W +P C+
Sbjct: 90 SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCV 147
Score = 42.4 bits (98), Expect = 0.009
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 446 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 503 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 779 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 826
Query: 562 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 609
+ G P + + G P I S M + D+
Sbjct: 827 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 886
Query: 610 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 655
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 887 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 946
Query: 656 LIGEKSIVCQENNQWSANIPIC 677
L G CQ ++QW+ + +C
Sbjct: 947 LEGSPQSQCQSDHQWNPPLAVC 968
Score = 38.9 bits (89), Expect = 0.095
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 1660 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1718 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1764
C P G + G S Y SV C + ++ V+ Q
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 1765 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1823
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
Query: 1824 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1874
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
Query: 1875 AIRCETVPNSLAQWNDSLPTC 1895
+ RC +A W +P C
Sbjct: 253 SSRCVIAGQGVA-WT-KMPVC 271
Score = 37.7 bits (86), Expect = 0.21
Identities = 74/300 (24%), Positives = 108/300 (36%), Gaps = 61/300 (20%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C G NGK + +G T F CDE Y LQG S C IA AW+ PVC+
Sbjct: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCE 272
Query: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTL 563
C S +G + +N ++T + + +NF + IG TL
Sbjct: 273 EIFCPSPPPILNGRHIGNSL-----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTL 323
Query: 564 TIG-DGGEVGD-----PRTVL----------QVLTGSFVPDLIVSMSSQMWLHLQTDESV 607
D + G PR L Q+L G V S Q + D +
Sbjct: 324 RCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVI 376
Query: 608 GSVGFKVNYKEIEKESCGDPGT--PLYGIREGD----------GFSNRDVLRFE------ 649
+ F K ++ C GT P + E + +R ++RF+
Sbjct: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
Query: 650 --CQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 702
C G+ L+GE+SI C W+ +P C + C + T P + PD G
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
Score = 35.8 bits (81), Expect = 0.80
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 969 SCLDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPT 1022
SC P ++GR Y ++G+ + +SC +RL E+ LLC + + W P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1023 CD 1024
C+
Sbjct: 82 CE 83
Score = 35.8 bits (81), Expect = 0.80
Identities = 56/279 (20%), Positives = 105/279 (37%), Gaps = 63/279 (22%)
Query: 1134 FSEYNLEPCEDPGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS- 1191
F++Y+ C +P +P Y R + GD++TF+C + + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGP 140
Query: 1192 APLPRCVA----ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1247
LP CV+ EC P P+ + +H + G + S + +
Sbjct: 141 TRLPTCVSVFPLEC-------------PALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
Query: 1248 LAQGD--VLKIYDGK---------DKTTHLLGAFTGASMR-------GLTLSSTSNQLW- 1288
L G+ + + GK + LG F ++ G+T + ++ +
Sbjct: 188 LLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247
Query: 1289 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP---------QFGYKISDQGHFAGSTIIY 1339
L+ + G + +T + CE+ P G +++ + GS + Y
Sbjct: 248 LQGPPSSRCVIAGQGVAWTKMPV--CEEIFCPSPPPILNGRHIGNSLANVSY--GSIVTY 303
Query: 1340 GCNP------GYTLHGSSLLKCMTGERR--AWDYPLPSC 1370
C+P + L G S L+C ++ W P P C
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342
Score = 35.8 bits (81), Expect = 0.80
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 138 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 906
Query: 195 CR 196
C+
Sbjct: 907 CK 908
Score = 35.8 bits (81), Expect = 0.80
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 1028
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 931 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 35.0 bits (79), Expect = 1.4
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 446 CPDPGEPENG----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 501
CP NG + +GS + G +V +SC+ Y+L G K I C + WS P
Sbjct: 154 CPALPMIHNGHHTSENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPP 208
Query: 502 VCKVKTCGSNLQGPSGTFTSP 522
C+ C S + P+G P
Sbjct: 209 TCEEARCKSLGRFPNGKVKEP 229
Score = 35.0 bits (79), Expect = 1.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 648 FECQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSNFTAPMGTVLSP 695
+ C+ G+ L+GEK I C + +WSA P C C S P G V P
Sbjct: 181 YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEP 229
Score = 34.7 bits (78), Expect = 1.8
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
F G+++ Y C G+ L G +L C ++S SW P P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 33.1 bits (74), Expect = 5.2
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 131 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 908 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 963
Query: 191 PVPICRA 197
P+ +CR+
Sbjct: 964 PLAVCRS 970
Score = 32.3 bits (72), Expect = 8.9
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 136 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 183
SSC P VP + G T + GD + ++C T + ++G+ + C AN++
Sbjct: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM 137
Score = 32.3 bits (72), Expect = 8.9
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 446 CPDPGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQ 487
CP+P P K GS + G +V F+C ++ + G KS+ CQ
Sbjct: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 258 bits (660), Expect = 6e-68
Identities = 163/561 (29%), Positives = 248/561 (44%), Gaps = 46/561 (8%)
Query: 2669 IVNGSH----YEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPT 2724
++N SH + + ++ F C GY GP+ +ECL +G W+ N+ P C C L
Sbjct: 210 LMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT--NKPPQCLAAQCPPLKI 267
Query: 2725 PPNGNKIGTQTS----YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIP 2780
P GN ++ + S+ F+C+ GF LVG V +C +SG+W+ C A C
Sbjct: 268 PERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHL 327
Query: 2781 ELIVNGQVIGEN----YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCG 2836
E G + + + Y + ++C PG+R+ G + C +WS LP+C +SC
Sbjct: 328 EAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCE 387
Query: 2837 HPGSPIYG----RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVN 2892
SP++G S F ++ +F C G++++G +C QW+ P P+C+ +
Sbjct: 388 PLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQ 447
Query: 2893 CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIM 2952
C D +P ++ G F Y +V + CN G L G+SVL C G W+ PEC
Sbjct: 448 CQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQA 507
Query: 2953 IDCGHPGVPPNAVLSGEK----YTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3008
I C P N ++ + ++ ST + C SL G C +G W+ S P C
Sbjct: 508 IPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Query: 3009 SGDATGTCGDPGTPGHGSRQESN----FRTKSTVRYACDTGYILHGSEERTCLANGSWTG 3064
C + P GS S+ F ST ++CD G+ L G C +G W+
Sbjct: 568 EAI---KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSA 624
Query: 3065 RQPECK--------AVQCGNPGTTANGKVF--RIDGT-TFSSSVIYSCMEGYILSGPSVR 3113
P CK VQC T G ++ GT F+++ + C G+ L G S
Sbjct: 625 TPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTL 684
Query: 3114 QCTANGTWSGTLPNCTIISCGD----PGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNG 3169
C +G W+ P C + C + I N ++ G S+ C G LNG
Sbjct: 685 SCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQL--LNG 742
Query: 3170 SRIRTCTINGTWSGVMPTCRA 3190
S C NG WS +PTC+A
Sbjct: 743 SAQTACQENGHWSTTVPTCQA 763
Score = 242 bits (617), Expect = 6e-63
Identities = 164/579 (28%), Positives = 241/579 (41%), Gaps = 59/579 (10%)
Query: 2826 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2885
+LP V ++C HP GN F+FN +F C GY + GP+K +C A+ W++ P
Sbjct: 204 ELPQHVLMNCSHP--------LGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKP 254
Query: 2886 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2945
P C C IP F + + + C G+ L G V+ C +G W
Sbjct: 255 PQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTA 314
Query: 2946 PLPECIMIDCGHPGVPPNAVLSG----EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 3001
P P C + C H P + + +GS+ + C + G C +GHW
Sbjct: 315 PAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHW 374
Query: 3002 SGSQPHCSGDATGTCGDPGTPGHGSRQESN----FRTKSTVRYACDTGYILHGSEERTCL 3057
S P C + C +P HGS S F+ + + C G++L G++ C
Sbjct: 375 SAPLPTCEAIS---CEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCD 431
Query: 3058 ANGSWTGRQPECKAVQCGNPGTTANGKV---FRIDGTTFSSSVIYSCMEGYILSGPSVRQ 3114
G WT P C+A+QC + +V + S ++C EG +L G SV Q
Sbjct: 432 NLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQ 491
Query: 3115 CTANGTWSGTLPNCTIISCGDPGIPANG----LRYGDDYVVGQNVSYMCQPGYTMELNGS 3170
C A G W+ P C I C P NG ++ ++C GY+ L+G
Sbjct: 492 CLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYS--LSGP 549
Query: 3171 RIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN----FDWGFSISYICSPGYELS 3226
CT +G W+ P C A+ CP G L+ ++ F+ G + + C G++L
Sbjct: 550 ERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLE 609
Query: 3227 FPAVLTCVGNGTWSGEVPQC-----LPKFCGDPGI-------PAQG----KREGKSFIYQ 3270
P + C +G WS P C LP PG+ P QG + +F +
Sbjct: 610 GPNNVECTTSGRWSATPPTCKGIASLPT----PGVQCPALTTPGQGTMYCRHHPGTFGFN 665
Query: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN--NTFG 3328
+ F CN F L+G ST C+ G W+ +P C C V + + N N +G
Sbjct: 666 TTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPAC---RAVKCSELHVNKPIAMNCSNLWG 722
Query: 3329 -FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3366
F GS+ FHC +G LL GS C + WS P C
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 239 bits (609), Expect = 5e-62
Identities = 170/612 (27%), Positives = 251/612 (41%), Gaps = 83/612 (13%)
Query: 2684 SCDPGYHGLGPASIECLPNGTWSWRNERPYCQII-SCGELPTPPN-----GNKIGTQTSY 2737
SC PG++G P C+ + CGEL P + + +G S+
Sbjct: 184 SCYPGFYG--------------------PECEYVRECGELELPQHVLMNCSHPLGN-FSF 222
Query: 2738 GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVI----GENY 2793
S F C G+ + G + ECL+SG+W+ +CLA C ++ G + + +
Sbjct: 223 NSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAF 282
Query: 2794 GYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG----N 2849
++ + + C GF L+G V C W+ P C V C H +P G
Sbjct: 283 QHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLT 342
Query: 2850 GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIE 2909
F + F C GY ++G +C + WS P P C+ ++C P + +
Sbjct: 343 AFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPS 402
Query: 2910 HGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGE 2969
F Y T + C G+ L G+ ++ C GQW P P C + C VP A ++
Sbjct: 403 LRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCS 462
Query: 2970 ----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG----------DATGT 3015
+ + S ++C L+G S C G+W+ P C + T T
Sbjct: 463 HPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMT 522
Query: 3016 CGDP-GTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC 3074
C P G+ + KST ++ CD GY L G E C +G WT P C+A++C
Sbjct: 523 CVQPLGSSSY----------KSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKC 572
Query: 3075 GNPGTTANGKVFRIDGT---TFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT-I 3130
G + D S+ +SC G+ L GP+ +CT +G WS T P C I
Sbjct: 573 PELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGI 632
Query: 3131 ISCGDPGI-------PANGLRYGDDY--VVGQNVS--YMCQPGYTMELNGSRIRTCTING 3179
S PG+ P G Y + G N + + C G+T L G +C +G
Sbjct: 633 ASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFT--LIGDSTLSCRPSG 690
Query: 3180 TWSGVMPTCRAVTCP-----TPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCV 3234
W+ V P CRAV C P ++ L G NF +G S+ C G L+ A C
Sbjct: 691 QWTAVTPACRAVKCSELHVNKPIAMNCSNLWG-NFSYGSICSFHCLEGQLLNGSAQTACQ 749
Query: 3235 GNGTWSGEVPQC 3246
NG WS VP C
Sbjct: 750 ENGHWSTTVPTC 761
Score = 226 bits (575), Expect = 4e-58
Identities = 153/549 (27%), Positives = 231/549 (42%), Gaps = 42/549 (7%)
Query: 2792 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRT----S 2847
N+ + + C G+++ G S C W+ + P C+ C P G S
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHS 278
Query: 2848 GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESK 2907
F +FSC G+ + GP QC A+ W+ P P+CK V C P+ +
Sbjct: 279 AKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCV 338
Query: 2908 IEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVL- 2966
F YG+ ++C PGY + G +L C +G W PLP C I C P + +
Sbjct: 339 HPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMD 398
Query: 2967 ---SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPG 3023
S + + + + C L G C G W+ P C C D P
Sbjct: 399 CSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQ---ALQCQDLPVPN 455
Query: 3024 HG----SRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT 3079
S FR +S + C+ G +L G+ CLA G+W PEC+A+ C +
Sbjct: 456 EARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS 515
Query: 3080 TANGK---VFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDP 3136
NG V + +++ S+ + C EGY LSGP CT +G W+ + P C I C +
Sbjct: 516 PQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPEL 575
Query: 3137 GIPANG-LRYGD---DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV- 3191
P G L D ++ VG + C G+ +E G CT +G WS PTC+ +
Sbjct: 576 FAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLE--GPNNVECTTSGRWSATPPTCKGIA 633
Query: 3192 TCPTP----PQISNGRLEGTNF------DWGFSIS--YICSPGYELSFPAVLTCVGNGTW 3239
+ PTP P ++ +GT + +GF+ + + C+ G+ L + L+C +G W
Sbjct: 634 SLPTPGVQCPALTTPG-QGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQW 692
Query: 3240 SGEVPQCLPKFCGD----PGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADG 3295
+ P C C + I +F Y S SF C +L GS+ CQ +G
Sbjct: 693 TAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENG 752
Query: 3296 TWSGSSPHC 3304
WS + P C
Sbjct: 753 HWSTTVPTC 761
Score = 216 bits (550), Expect = 3e-55
Identities = 144/519 (27%), Positives = 220/519 (42%), Gaps = 50/519 (9%)
Query: 2525 IAFYCSTPESPPHGYII---SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2581
+A C + P G + S Q S ++C+ GF LVG C S W
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG----VWT 313
Query: 2582 APVPACQAISCGIPKAPTNGGI----LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSD 2637
AP P C+A+ C +AP+ G + T + G+ + C GYR+ ++ C
Sbjct: 314 APAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLR--CIDS 371
Query: 2638 GTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH-YEYKTKVVFSCDPGYHGLGPAS 2696
G WS P C ++C + S + HG ++Y T F C G+ G
Sbjct: 372 GHWS--APLPTCEAISCEPLESPV--HGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADI 427
Query: 2697 IECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYG-----STAIFTCDLGFML 2751
+ C + W P CQ + C +LP PN ++ +G S FTC+ G +L
Sbjct: 428 VRC--DNLGQWTAPAPVCQALQCQDLPV-PNEARVNCSHPFGAFRYQSVCSFTCNEGLLL 484
Query: 2752 VGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG-----QVIGENYGYRDTVVYQCNPG 2806
VG++V +CL++G W+ C A C NG Q +G + Y+ T + C+ G
Sbjct: 485 VGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEG 543
Query: 2807 FRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR-----TSGNGFNFNDVVTFSC 2861
+ L G C + W+ P C + C +P G T G FN FSC
Sbjct: 544 YSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGE-FNVGSTCHFSC 602
Query: 2862 NIGYLMQGPTKAQCQANRQWSHPPPMCK-VVNCSDPGI-------PANSKRESKIEHGNF 2913
+ G+ ++GP +C + +WS PP CK + + PG+ P + G F
Sbjct: 603 DNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTF 662
Query: 2914 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCG----HPGVPPNAVLSGE 2969
+ T ++ CN G+ L G S L C+P+GQW P C + C + + N
Sbjct: 663 GFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWG 722
Query: 2970 KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3008
+++GS + C + L G + CQ NGHWS + P C
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 202 bits (515), Expect = 4e-51
Identities = 167/643 (25%), Positives = 257/643 (39%), Gaps = 82/643 (12%)
Query: 2829 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP-PM 2887
SC +SC G + T GN T SC G+ GP +C+ R+ P
Sbjct: 162 SCQDMSCSKQGECL--ETIGN-------YTCSCYPGFY--GP---ECEYVRECGELELPQ 207
Query: 2888 CKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPL 2947
++NCS P GNF++ + + C GY + G S L C +G W
Sbjct: 208 HVLMNCSHP-------------LGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKP 254
Query: 2948 PECIMIDCGHPGVPPNAVL----SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 3003
P+C+ C +P + S + + S+ +SC +L+G C +G W+
Sbjct: 255 PQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTA 314
Query: 3004 SQPHCSGDATGTCGDPGTPGHGSRQ----ESNFRTKSTVRYACDTGYILHGSEERTCLAN 3059
P C C P G+ + F S+ ++ C GY + G + C+ +
Sbjct: 315 PAPVCKAVQ---CQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDS 371
Query: 3060 GSWTGRQPECKAVQCGNPGTTANGKVF---RIDGTTFSSSVIYSCMEGYILSGPSVRQCT 3116
G W+ P C+A+ C + +G + + + ++ + C EG++L G + +C
Sbjct: 372 GHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCD 431
Query: 3117 ANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVG----QNV-SYMCQPGYTMELNGSR 3171
G W+ P C + C D +P N R + G Q+V S+ C G + L G+
Sbjct: 432 NLGQWTAPAPVCQALQCQDLPVP-NEARVNCSHPFGAFRYQSVCSFTCNEG--LLLVGAS 488
Query: 3172 IRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT----NFDWGFSISYICSPGYELSF 3227
+ C G W+ V P C+A+ C NG + + + + +IC GY LS
Sbjct: 489 VLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSG 548
Query: 3228 PAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS----FIYQSEVSFSCNFPFIL 3283
P L C +G W+ P C C + P QG + F S FSC+ F L
Sbjct: 549 PERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKL 608
Query: 3284 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV-------PRHGSQN-----NTFGFQV 3331
G + C G WS + P C S PGV P G+ TFGF
Sbjct: 609 EGPNNVECTTSGRWSATPPTC--KGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFN- 665
Query: 3332 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-----PETPAHANVVGMD 3386
+ F C G L G +T +C P W+ + P C C + P +N+ G
Sbjct: 666 -TTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNF 724
Query: 3387 LPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3429
S+G + C G L G+ C+ + W+ VP C+AG
Sbjct: 725 --SYGSICSFHCLEGQLL-NGSAQTACQENGHWSTTVPTCQAG 764
Score = 196 bits (497), Expect = 5e-49
Identities = 145/553 (26%), Positives = 228/553 (41%), Gaps = 42/553 (7%)
Query: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTD- 2607
NS + C G+++ G S C S W P C A C K P G +
Sbjct: 223 NSQCSFHCTDGYQVNGPSKLECLASGI----WTNKPPQCLAAQCPPLKIPERGNMTCLHS 278
Query: 2608 ---YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEH 2664
+ + ++ C +G+ L E+ C + G W+ P C V C + +
Sbjct: 279 AKAFQHQSSCSFSCEEGFALVGPEVVQ--CTASGVWTA--PAPVCKAVQCQHLEA--PSE 332
Query: 2665 GRWRIVNG-SHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELP 2723
G V+ + + Y + F C PGY G + C+ +G WS P C+ ISC L
Sbjct: 333 GTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWS--APLPTCEAISCEPLE 390
Query: 2724 TPPNGNKIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG- 2778
+P +G+ + + Y + F C GFML G+ + C + G W+ C A C
Sbjct: 391 SPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQD 450
Query: 2779 --IP-ELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSC 2835
+P E VN + Y+ + CN G L+G+SV C NW+ P C + C
Sbjct: 451 LPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 510
Query: 2836 GHPGSPIYGRTSG----NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2891
SP G + ++ F C+ GY + GP + C + +W+ PPMC+ +
Sbjct: 511 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 570
Query: 2892 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2951
C + P + G F G+ + C+ G+ L G + + C +G+W P C
Sbjct: 571 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 630
Query: 2952 MI-DCGHPGVPPNAVLS---GEKY------TFG--STVHYSCTGKRSLLGQSSRTCQLNG 2999
I PGV A+ + G Y TFG +T ++ C +L+G S+ +C+ +G
Sbjct: 631 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 690
Query: 3000 HWSGSQPHCSGDATGTCG-DPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLA 3058
W+ P C + + S NF S + C G +L+GS + C
Sbjct: 691 QWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQE 750
Query: 3059 NGSWTGRQPECKA 3071
NG W+ P C+A
Sbjct: 751 NGHWSTTVPTCQA 763
Score = 151 bits (381), Expect = 1e-35
Identities = 116/394 (29%), Positives = 161/394 (40%), Gaps = 44/394 (11%)
Query: 2526 AFYCSTPESPPHGYII---SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2582
A C ESP HG + S Q ++ + C GF L G C W A
Sbjct: 383 AISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ----WTA 438
Query: 2583 PVPACQAISCGIPKAPTNGGILTTDYLVGTRV----TYFCNDGYRLSSKELTTAVCQSDG 2638
P P CQA+ C P + + R ++ CN+G L + C + G
Sbjct: 439 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQ--CLATG 496
Query: 2639 TWSNHNKTPRCVVVTCPSINSFILEHGRWRIVN--GSHYEYKTKVVFSCDPGYHGLGPAS 2696
W++ P C + C + S ++G V GS YK+ F CD GY GP
Sbjct: 497 NWNS--VPPECQAIPCTPLLS--PQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPER 551
Query: 2697 IECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT----SYGSTAIFTCDLGFMLV 2752
++C +G W+ + P C+ I C EL P G+ + T + GST F+CD GF L
Sbjct: 552 LDCTRSGRWT--DSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLE 609
Query: 2753 GSAVRECLSSGLWSESETRCLAGHCGIPE-------LIVNGQVI------GENYGYRDTV 2799
G EC +SG WS + C G +P L GQ +G+ T
Sbjct: 610 GPNNVECTTSGRWSATPPTC-KGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTC 668
Query: 2800 VYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCG--HPGSPIYGRTSG--NGFNFND 2855
+ CN GF LIG S C+ W+ P+C V C H PI S F++
Sbjct: 669 YFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGS 728
Query: 2856 VVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2889
+ +F C G L+ G + CQ N WS P C+
Sbjct: 729 ICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 97.4 bits (241), Expect = 2e-19
Identities = 75/278 (26%), Positives = 119/278 (42%), Gaps = 32/278 (11%)
Query: 2526 AFYCSTPESPPHGYI--ISQTGGQ-LNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2582
A C+ SP +G + + G S ++ CD G+ L G C +S W
Sbjct: 507 AIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSG----RWTD 562
Query: 2583 PVPACQAISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDG 2638
P C+AI C AP G + +D + VG+ + C++G++L C + G
Sbjct: 563 SPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPN--NVECTTSG 620
Query: 2639 TWSNHNKTPRCVV------VTCPSINSFILEHGRWRIVNGSH---YEYKTKVVFSCDPGY 2689
WS T + + V CP++ + G+ + H + + T F C+ G+
Sbjct: 621 RWSATPPTCKGIASLPTPGVQCPALTT----PGQGTMYCRHHPGTFGFNTTCYFGCNAGF 676
Query: 2690 HGLGPASIECLPNGTWSWRNERPYCQIISCGEL----PTPPNGNKIGTQTSYGSTAIFTC 2745
+G +++ C P+G W+ P C+ + C EL P N + + SYGS F C
Sbjct: 677 TLIGDSTLSCRPSGQWT--AVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 734
Query: 2746 DLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELI 2783
G +L GSA C +G WS + C AG I E +
Sbjct: 735 LEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEAL 772
Score = 70.5 bits (171), Expect = 3e-11
Identities = 50/189 (26%), Positives = 77/189 (40%), Gaps = 10/189 (5%)
Query: 3266 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQ-- 3323
+F + S+ SF C + + G S C A G W+ P C+ C +P G+
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLA---AQCPPLKIPERGNMTC 275
Query: 3324 -NNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN- 3381
++ FQ S F C++G L G C W+ P C C+ E P+
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTM 335
Query: 3382 --VVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3439
V + ++G + + CQPG+ + G R C W+ +P CEA S ++ P
Sbjct: 336 DCVHPLTAFAYGSSCKFECQPGYRVRGLDMLR-CIDSGHWSAPLPTCEAISCEPLESPVH 394
Query: 3440 ALGTPSPKL 3448
SP L
Sbjct: 395 GSMDCSPSL 403
Score = 64.3 bits (155), Expect = 2e-09
Identities = 111/485 (22%), Positives = 171/485 (35%), Gaps = 123/485 (25%)
Query: 793 ECPDPGIP----INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 848
+CP IP + FQ SS S CEEGF G E + C +W+
Sbjct: 261 QCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALV-GPEVVQCTASG---VWTAPA 316
Query: 849 PKCGAPCGGHFSAPSGVILSPGWP-GYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYD 907
P C A H APS + P + +C++ E +PG+ ++ D
Sbjct: 317 PVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKF--ECQPGYRVR----------GLD 364
Query: 908 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 967
+L D + +PL T
Sbjct: 365 MLRCIDSGHWSAPL-----------------------------------------PTCEA 383
Query: 968 YSCLDPGIPVHGRRYGHD----FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
SC PVHG F + SF C G+ L + + C+ W+ P P C
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVC 443
Query: 1024 DALCGGDVRGPSGTILSPGYP--EFYPNSLNCTWTVD---VTHGKGV-----QFNFHTFH 1073
AL D+ P+ ++ +P F S+ C++T + + G V N+++
Sbjct: 444 QALQCQDLPVPNEARVNCSHPFGAFRYQSV-CSFTCNEGLLLVGASVLQCLATGNWNSVP 502
Query: 1074 LEDHH---DYLLITENGSFT--QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1128
E LL +NG+ T QPL ++++ +FI D S
Sbjct: 503 PECQAIPCTPLLSPQNGTMTCVQPLGS---------------SSYKSTCQFICDEGYSLS 547
Query: 1129 G---FNITFS-EYNLEP-------CEDPGIPQYGSR----IGFNFGIGDTLTFSCSSGYR 1173
G + T S + P C + P+ GS F +G T FSC +G++
Sbjct: 548 GPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFK 607
Query: 1174 LEGTSEIICLGGGRRVWSAPLPRCV---------AECGASATNNEGILLSPNYPLNYENN 1224
LEG + + C GR WSA P C +C A T +G + ++P + N
Sbjct: 608 LEGPNNVECTTSGR--WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFN 665
Query: 1225 HECIY 1229
C +
Sbjct: 666 TTCYF 670
Score = 59.3 bits (142), Expect = 7e-08
Identities = 106/456 (23%), Positives = 169/456 (37%), Gaps = 87/456 (19%)
Query: 1117 LRFISDFSIS-YEGFNITFSEYNLEPCEDPGIPQY-----GSRIGFNFGIGDTLTFSCSS 1170
L I +++ S Y GF EY E C + +PQ+ +G NF +F C+
Sbjct: 175 LETIGNYTCSCYPGFYGPECEYVRE-CGELELPQHVLMNCSHPLG-NFSFNSQCSFHCTD 232
Query: 1171 GYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHECIY 1229
GY++ G S++ CL G +W+ P+C+A +C P + N C++
Sbjct: 233 GYQVNGPSKLECLASG--IWTNKPPQCLAAQC-------------PPLKIPERGNMTCLH 277
Query: 1230 SIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWL 1289
S + + S+ +F +G L + T G +T + +
Sbjct: 278 SAKAFQHQ----SSCSFSCEEGFALVGPEVVQCTAS--GVWTAPAPVCKAVQCQ------ 325
Query: 1290 EFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1349
+ +EGT + C P + F Y GS+ + C PGY + G
Sbjct: 326 HLEAPSEGTMD-------------CVHP-LTAFAY---------GSSCKFECQPGYRVRG 362
Query: 1350 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRI-LSPGY-PFPYDNN--LRCMWMI 1405
+L+C+ + W PLP+C A + G + SP F YD N RC
Sbjct: 363 LDMLRCI--DSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF 420
Query: 1406 EVDPGNIVSLQFLAFDTEASH--DILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTI 1463
+ +IV L T + L+ D P N+ + P G ++ +
Sbjct: 421 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARV----NCSHPFGAFRYQSVCSF 476
Query: 1464 QFDTDFYISKSG----FAIQFSSSVATACRD-PGVPMNGTRNG--------DGREPGDTV 1510
+ + + A +SV C+ P P+ +NG T
Sbjct: 477 TCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTC 536
Query: 1511 VFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1546
F CD GY L G ER+ C + W SPP+C A
Sbjct: 537 QFICDEGYSLSGPERLDCTRSGR---WTDSPPMCEA 569
Score = 56.6 bits (135), Expect = 4e-07
Identities = 109/514 (21%), Positives = 172/514 (33%), Gaps = 83/514 (16%)
Query: 1646 YTGFH---LEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCI 1702
Y GF+ EY + E +MN + ++ S +++C GY + G S L C+
Sbjct: 186 YPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECL 245
Query: 1703 MGDDGRPGWNRALPSC-HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVF 1761
W P C A C G + + K + +C +S + F +
Sbjct: 246 ASGI----WTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCE--EGFALV 299
Query: 1762 GQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGES---LPLSS-GNQITIRFTSVGP 1817
G V T+ V P ++ L G PL++ + +F
Sbjct: 300 GPEVVQCTA--SGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPG 357
Query: 1818 ITAKGFHFVY--------QAVPRTSSTQCSSVPEPRFGRRIGNE----FAVGSSVLFDCN 1865
+G + +P + C + P G + F ++ F C
Sbjct: 358 YRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCA 417
Query: 1866 PGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNC 1925
G++L G+ +RC+ +L QW P C + P P + +NC
Sbjct: 418 EGFMLRGADIVRCD----NLGQWTAPAPVC------------QALQCQDLPVPNEARVNC 461
Query: 1926 -----------VWKITVPEGAG-IQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGT- 1972
V T EG + V+ NW+S+ P L +GT
Sbjct: 462 SHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTM 521
Query: 1973 TIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIG--LDS--------CPEPQTPSSG 2021
T L S+S F D S +G L+ T G DS CPE P G
Sbjct: 522 TCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQG 581
Query: 2022 -IKIGD---RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICL--------- 2068
+ D + VG F CD G+ L+G +++ C RW+ P C
Sbjct: 582 SLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTS--GRWSATPPTCKGIASLPTPG 639
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIN 2102
QC + G + PG + + C + N
Sbjct: 640 VQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCN 673
Score = 53.5 bits (127), Expect = 4e-06
Identities = 121/600 (20%), Positives = 189/600 (31%), Gaps = 168/600 (28%)
Query: 1512 FQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAP-CGGNLTGSSGFILSPNFPHPYPH 1570
F C GY++ G ++ C+ W PP C+A C G + + + H
Sbjct: 228 FHCTDGYQVNGPSKLECLASG---IWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQH 284
Query: 1571 SRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESS 1630
C SFS E + + GP+ + P + +
Sbjct: 285 QSSC-----------------SFSCEEGFALV----GPEVVQCTASGVWTAPAP--VCKA 321
Query: 1631 SNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAG 1690
HL S+G++ C P + GS+ + C G
Sbjct: 322 VQCQHLEAPSEGTMD---------------CVHPLTA---------FAYGSSCKFECQPG 357
Query: 1691 YVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1749
Y ++G L CI D G W+ LP+C A C + G++ + + NC
Sbjct: 358 YRVRGLDMLRCI--DSGH--WSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCS 413
Query: 1750 YSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQIT 1809
+ A + F++ G +
Sbjct: 414 FRCA--EGFMLRGADI-------------------------------------------- 427
Query: 1810 IRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGR----RIGNEFAVGSSVLFDCN 1865
+R ++G TA P + QC +P P R F S F CN
Sbjct: 428 VRCDNLGQWTAPA--------PVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCN 479
Query: 1866 PGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGT--------------- 1909
G +L G+ ++C N WN P C +PC +L+ + GT
Sbjct: 480 EGLLLVGASVLQCLATGN----WNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKST 535
Query: 1910 ---ILSPGYPEPYDNNLNCV----WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNN 1962
I GY L+C W + P I+ + FA E SLD D
Sbjct: 536 CQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPEL-FAPEQG--SLDCSD----- 587
Query: 1963 APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG--FHLEYTAIGLDSCPEP----- 2015
G ++ + H S N L +++ + +G T G+ S P P
Sbjct: 588 --TRGEFNVGSTCHF--SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCP 643
Query: 2016 --QTPSSGIKI----GDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2069
TP G + F C+ G++L G S ++C P +W P C A
Sbjct: 644 ALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPS--GQWTAVTPACRA 701
Score = 52.8 bits (125), Expect = 6e-06
Identities = 91/450 (20%), Positives = 161/450 (35%), Gaps = 80/450 (17%)
Query: 634 IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVL 693
+ F ++ F C+ GF L+G + + C + W+A P+C + AP +
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTM 335
Query: 694 SPDYP-EGYGNNLNCIWTIISDPGSRIH-----LSFNDFDLESQFDFLAVKDGDSPESPI 747
+P + +C + PG R+ + + + ESP+
Sbjct: 336 DCVHPLTAFAYGSSCKFEC--QPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV 393
Query: 748 LGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY-NTFGH----------NECPD 796
G+ + L + + F+ RG +I + G +C D
Sbjct: 394 HGSM---DCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQD 450
Query: 797 PGIPINAR-----RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
+P AR FG F+ S S C EG + G + C+ W+ + P+C
Sbjct: 451 LPVPNEARVNCSHPFGA-FRYQSVCSFTCNEGLLLV-GASVLQCLATGN---WNSVPPEC 505
Query: 852 GA-PCGGHFSAPSGVI--LSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNY-- 906
A PC S +G + + P YK + C+++ + G+S+ ER +
Sbjct: 506 QAIPCTPLLSPQNGTMTCVQPLGSSSYKST--CQFI--CDEGYSLSGP-ERLDCTRSGRW 560
Query: 907 ----DVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKI---- 958
+ E P L +P GS + S + + + +T + +NGFK+
Sbjct: 561 TDSPPMCEAIKCPELFAPEQGSLD--------CSDTRGEFNVGSTCHFSCDNGFKLEGPN 612
Query: 959 HYESVTVNTYSCLDP------GIPVHG----------------RRYGHDFSIGSTVSFSC 996
+ E T +S P +P G R + F +T F C
Sbjct: 613 NVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGC 672
Query: 997 DSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 1026
++G+ L + L C + W+ P C A+
Sbjct: 673 NAGFTLIGDSTLSCRPSGQWTAVTPACRAV 702
Score = 46.6 bits (109), Expect = 5e-04
Identities = 51/217 (23%), Positives = 80/217 (36%), Gaps = 46/217 (21%)
Query: 985 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILS-PGY 1043
+F++GST FSCD+G++L + C + WS PTC + G L+ PG
Sbjct: 591 EFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQ 650
Query: 1044 PEFYPNSLNCTWTVDVTHGKGVQFNFHTF-HLEDHHDYLLITENGSFTQPLARLTGSDLP 1102
Y H G F F+T + + + LI ++ +P + T +
Sbjct: 651 GTMY-----------CRHHPGT-FGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTA--VT 696
Query: 1103 PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGD 1162
P A + SE ++ + I S + NF G
Sbjct: 697 PACRA------------------------VKCSELHV----NKPIAMNCSNLWGNFSYGS 728
Query: 1163 TLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1199
+F C G L G+++ C G WS +P C A
Sbjct: 729 ICSFHCLEGQLLNGSAQTACQENGH--WSTTVPTCQA 763
Score = 45.8 bits (107), Expect = 8e-04
Identities = 64/261 (24%), Positives = 98/261 (37%), Gaps = 47/261 (18%)
Query: 987 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEF 1046
S ST F CD GY LS E L C ++ W+ P C+A+ ++ P
Sbjct: 531 SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE----------- 579
Query: 1047 YPNSLNCTWTVDVTHGKGVQFNF-HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTI 1105
SL+C+ T +G +FN T H + + L N R + + PPT
Sbjct: 580 -QGSLDCSDT------RG-EFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSAT--PPTC 629
Query: 1106 NAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLT 1165
G + +++ G + ++ PG FG T
Sbjct: 630 K----GIASLPTPGVQCPALTTPGQGTMYCRHH------PG----------TFGFNTTCY 669
Query: 1166 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENN 1224
F C++G+ L G S + C G+ W+A P C A +C N + N N+
Sbjct: 670 FGCNAGFTLIGDSTLSCRPSGQ--WTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYG 727
Query: 1225 HECIYSIQVQAGKGINISART 1245
C S G+ +N SA+T
Sbjct: 728 SIC--SFHCLEGQLLNGSAQT 746
Score = 42.4 bits (98), Expect = 0.009
Identities = 53/240 (22%), Positives = 74/240 (30%), Gaps = 66/240 (27%)
Query: 446 CPDPGEPENGKRI----GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 501
CP PE G F S+ FSC+E + L G + + C W+ P
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQC----TASGVWTAPAP 317
Query: 502 VCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
VCK C +L+ PS + CV +TA + + G D
Sbjct: 318 VCKAVQC-QHLEAPS------------EGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLD 364
Query: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEK 621
L D G P L T E++
Sbjct: 365 MLRCIDSGHWSAP--------------------------LPTCEAI-------------- 384
Query: 622 ESCGDPGTPLYGIREGD----GFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
SC +P++G + F F C GF L G + C QW+A P+C
Sbjct: 385 -SCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVC 443
Score = 42.0 bits (97), Expect = 0.011
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 2200 FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2242
F G + FEC PGY + G L C+ S +W+ PLP CEA+
Sbjct: 344 FAYGSSCKFECQPGYRVRGLDMLRCID--SGHWSAPLPTCEAI 384
Score = 42.0 bits (97), Expect = 0.011
Identities = 64/265 (24%), Positives = 95/265 (35%), Gaps = 28/265 (10%)
Query: 2175 VYQAYQLQSCPDPRPFR-NGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWN 2233
V QA Q Q P P R N F SF C G L+G S L CL + NWN
Sbjct: 442 VCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCL--ATGNWN 499
Query: 2234 HPLPRCEAL-CGGNITAMNGT------IYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT 2286
P C+A+ C ++ NGT + S Y D + + P +
Sbjct: 500 SVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR 559
Query: 2287 VLQTEPIYDFITVWD--GPDQNSPQIGQFSG--NTALESVYSTSNQILIK--FHSDFTTS 2340
+ P+ + I + P+Q S G N +S N ++ + + TTS
Sbjct: 560 WTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTS 619
Query: 2341 GFFVLSYHAYQLRVCQPPPPVPNAEILT----------EDDEFEIGDIIRYQCLPGFTLV 2390
G + + + P P V + T F + C GFTL+
Sbjct: 620 GRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLI 679
Query: 2391 GNAILTCRLGERLQMDGAPPVCQVL 2415
G++ L+CR Q P C+ +
Sbjct: 680 GDSTLSCRPSG--QWTAVTPACRAV 702
Score = 42.0 bits (97), Expect = 0.011
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 8/63 (12%)
Query: 446 CPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 501
CP+ PE G SD F++GST FSCD + L+G ++ C WS P
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVEC----TTSGRWSATPP 627
Query: 502 VCK 504
CK
Sbjct: 628 TCK 630
Score = 40.0 bits (92), Expect = 0.043
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 452 PENG-----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVK 506
P+NG + +GS S ST QF CDE Y L G + + C R W+D P+C+
Sbjct: 516 PQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGR----WTDSPPMCEAI 570
Query: 507 TCGSNLQGPSGTFTSPNFPFQYDSNAQC 534
C G+ + +++ + C
Sbjct: 571 KCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Score = 36.2 bits (82), Expect = 0.61
Identities = 46/241 (19%), Positives = 75/241 (31%), Gaps = 73/241 (30%)
Query: 462 FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTS 521
F + F C E ++L+GA + C + + W+ PVC+ C
Sbjct: 406 FQYDTNCSFRCAEGFMLRGADIVRCDNLGQ----WTAPAPVCQALQC------------- 448
Query: 522 PNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVL 581
+ P ++ C A V E L +G +VLQ L
Sbjct: 449 QDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVG---------------ASVLQCL 493
Query: 582 -TGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREG--- 637
TG N+ + E P TPL + G
Sbjct: 494 ATG-------------------------------NWNSVPPECQAIPCTPLLSPQNGTMT 522
Query: 638 -----DGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSNFTAPMGT 691
S + +F C G+ L G + + C + +W+ + P+C C F G+
Sbjct: 523 CVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGS 582
Query: 692 V 692
+
Sbjct: 583 L 583
Score = 35.4 bits (80), Expect = 1.0
Identities = 15/38 (39%), Positives = 17/38 (44%)
Query: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
FS + F C G L G CQEN WS +P C
Sbjct: 724 FSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 35.0 bits (79), Expect = 1.4
Identities = 46/223 (20%), Positives = 73/223 (32%), Gaps = 63/223 (28%)
Query: 1507 GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI---------APCGGNLTGSSG 1557
G T F CD G++L+G + C W +PP C C T G
Sbjct: 595 GSTCHFSCDNGFKLEGPNNVECTTSGR---WSATPPTCKGIASLPTPGVQCPALTTPGQG 651
Query: 1558 FILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGS 1617
+ + P + + C Y G ++ LIG
Sbjct: 652 TMYCRHHPGTFGFNTTC------------------------------YFGCNAGFTLIG- 680
Query: 1618 FQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDY 1677
DS L R + A R+ K E + MN + L ++
Sbjct: 681 --DSTLSCRPSGQWTAVTPACRA--------------VKCSELHVNKPIAMNCSNLWGNF 724
Query: 1678 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1720
GS +++C G +L G + C ++G W+ +P+C A
Sbjct: 725 SYGSICSFHCLEGQLLNGSAQTAC--QENGH--WSTTVPTCQA 763
Score = 34.7 bits (78), Expect = 1.8
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 18/87 (20%)
Query: 152 TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGI 211
T F G ++ C GY + G L CI ++ W P+P C A
Sbjct: 342 TAFAYGSSCKFECQPGYRVRGLDMLRCI----DSGHWSAPLPTCEA-------------- 383
Query: 212 ISSPSFPNEYHNNADCTWTIVAEPGDT 238
IS + H + DC+ ++ A DT
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDT 410
Score = 32.7 bits (73), Expect = 6.8
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 1677 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPG--WNRALPSCHA-PCGSRSTGSEGTV 1733
+ +T + C+AG+ L G STL+C RP W P+C A C +
Sbjct: 662 FGFNTTCYFGCNAGFTLIGDSTLSC------RPSGQWTAVTPACRAVKCSELHVNKPIAM 715
Query: 1734 LSPNYPKNYSVGHNCVY 1750
N N+S G C +
Sbjct: 716 NCSNLWGNFSYGSICSF 732
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 233 bits (595), Expect = 2e-60
Identities = 167/515 (32%), Positives = 247/515 (47%), Gaps = 18/515 (3%)
Query: 1199 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1257
A C S +N EG + S +YPL NN EC Y++ V G G+ + ++ +L+ G++L I
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
Query: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1317
G D T + A + G + S +N + + F + + FQL Y +F LS C P
Sbjct: 339 -GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFP 396
Query: 1318 GIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1377
P G ++ +G + C+ GY L G+ +L C+ + W P C A CGG
Sbjct: 397 RRPDSG-DVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGA 455
Query: 1378 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1437
+ GR+LSP YP + + C+W IE G + L F D + V G
Sbjct: 456 VHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTN 514
Query: 1438 NDMLLKE-ISGSLIP-EGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
LL + + +P EG+ S N + I+F +D + S F I+F + C +P +
Sbjct: 515 KSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQN 574
Query: 1496 -NGTRNGDGREPGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1553
N T + G V F CDPG+ L QG I CI V + Y W + P+C A CGG L+
Sbjct: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLCRAMCGGELS 633
Query: 1554 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1613
+G +LSPN+P PY DC W I V + I L I F N D L IYDG +
Sbjct: 634 AVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNSDILTIYDGDEVMPH 692
Query: 1614 LIGSFQDSKLPERIESSSNTMHLAFRSDGS----VSYTGFHLEY-KAKLRESCFDPGNIM 1668
++G + + P+++ SS+ + + F SD + GF + Y + +SC D I
Sbjct: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQ 752
Query: 1669 NGTRLGMDYKL--GSTVTYYCDAGYVLQGYSTLTC 1701
NG + +L G+ +TY CD GY + G TLTC
Sbjct: 753 NGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC 787
Score = 228 bits (580), Expect = 1e-58
Identities = 191/714 (26%), Positives = 306/714 (42%), Gaps = 87/714 (12%)
Query: 1899 CGGILTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAGIQVQVVSF-ATEHNWDSLDFY 1956
C + +G I S YP P +N L C + +TV G G+++QV S ++ S+
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGV 340
Query: 1957 DGGDNNAPRLGSYSGTTI---PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 2013
DG P L + T+ ++ S +N + + F++ F L Y A L SC
Sbjct: 341 DG-----PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCN 394
Query: 2014 EPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
P+ P SG + + D + G V F C GY LQG +TC+ W+ PIC A CG
Sbjct: 395 FPRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
Query: 2073 GAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2131
GA+ + + G +LSP +P N S C WTI P G +HL F D + V SG
Sbjct: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQ 512
Query: 2132 SETSTVI-GRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2189
+ S ++ L +P L S + + F SD ++ F+I ++A++ C +P
Sbjct: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
Query: 2190 FRNGFVIGND--FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGN 2246
+NG +D + +G + F C PG++L G + + C++ WN P C A+CGG
Sbjct: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
Query: 2247 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2306
++A+ G + SP +P+ Y +DC W + V I+++ L D +T++DG +
Sbjct: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN-SDILTIYDGDEVM 690
Query: 2307 SPQIGQFSGNTALESVYSTSNQILIKFHSD-----FTTSGFFVLSY-HAYQLRVCQPPPP 2360
+GQ+ GN+ + +YS++ + I+FHSD F F+++Y + C P
Sbjct: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
Query: 2361 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2420
+ N T E G I YQC PG+ +VG+ LTC+ L PP C+ + +
Sbjct: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEKIMYCTD 808
Query: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI 2480
PG D L I
Sbjct: 809 -----------PGEVDHSTRL--------------------------------------I 819
Query: 2481 QSPV-LISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESP 2535
PV L+ + Y+ G + +S + G R+ + + C P P
Sbjct: 820 SDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP 879
Query: 2536 PHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
+GY I L + + C GF L+G+ + C + W+ P+P C+
Sbjct: 880 ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH--WNGPLPVCK 931
Score = 216 bits (549), Expect = 4e-55
Identities = 182/671 (27%), Positives = 290/671 (43%), Gaps = 40/671 (5%)
Query: 2069 AQCGGAMSDFSGVILSPGFP----GNYPSSLDCTWTINLPIGFGVHLQF--VNFSTETIH 2122
A C + S+ G I S +P N+ L+CT+ + + G+GV LQ VN S +
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNF---LECTYNVTVYTGYGVELQVKSVNLSDGEL- 334
Query: 2123 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
L +R T TV+ + + S T+ S+YF + F + YQA+ L
Sbjct: 335 --LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML- 391
Query: 2183 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2242
SC PR +G V D G F C GY L G LTC++ +W+ P C A
Sbjct: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
Query: 2243 CGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWD 2301
CGG + A G + SP YP+ Q C W + P G ++++F L D +TV
Sbjct: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHS 510
Query: 2302 GPDQNSPQIGQF--SGNTALESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPP 2358
G S + + + E + S N I I+F SD + F + + A++ C P
Sbjct: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
Query: 2359 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCP 2417
+ N T D + IG I+ + C PG +L G AI+ C + P+C+ +C
Sbjct: 571 Y-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC- 628
Query: 2418 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2477
EL + GV+LSP +P+ Y + C W I V + I + ++F D+L +YDG
Sbjct: 629 GGELSAVA-GVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 2478 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN----NKKGFRIRYIAFY----C 2529
+ +L G+ S + S+ ++ +Q+ +D +GF + YI C
Sbjct: 687 DEVMPHILGQYLGN-SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
Query: 2530 STPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
S +G+ S T + + + CD G+ +VG + C+ +W + P C+
Sbjct: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL----SWSSDPPFCE 801
Query: 2589 AIS-CGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2645
I C P + L +D LVGT + Y CN G+ L L T + GT ++
Sbjct: 802 KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR 861
Query: 2646 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTW 2705
P CV + ++ L ++I+ Y + F C G+ +G +I C+
Sbjct: 862 LPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS 921
Query: 2706 SWRNERPYCQI 2716
W P C++
Sbjct: 922 HWNGPLPVCKV 932
Score = 210 bits (535), Expect = 2e-53
Identities = 204/718 (28%), Positives = 307/718 (42%), Gaps = 88/718 (12%)
Query: 1546 APCGGNLTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1604
A C + + G+I S ++P P + +C + +TV Y + L S ++ + L I
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
Query: 1605 --YDGPD----SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1658
DGP +N L+ Q I S +NT+ + FR+ F L Y+A +
Sbjct: 338 RGVDGPTLTVLANQTLLVEGQV------IRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
Query: 1659 ESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
SC P +G MD G ++C GY LQG LTCI + +P W+ P C
Sbjct: 392 -SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASKPHWSSQEPIC 448
Query: 1719 HAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEV 1777
APCG + G VLSP+YP+N + C+++I P+ + F D + V
Sbjct: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
Query: 1778 YDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPRT 1833
+ G T +S+LL S ES+P LS GN I I FTS A F+ ++A +
Sbjct: 509 HSGQTNKSALLYD---SLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
Query: 1834 SSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWND 1890
+ P + G ++ + +G+ V F C+PG+ L G I C V + WND
Sbjct: 566 HCYE----PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WND 619
Query: 1891 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1950
+ P C CGG L+ G +LSP +PEPY +C+WKI V E I + + F N
Sbjct: 620 TEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNS 678
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSD----ISVSAAGFHLEYTA 2006
D L YDG + LG Y G + P L S++ +L + F SD I GF + Y
Sbjct: 679 DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
Query: 2007 IGL-DSCPEPQTPSSGIKIGD--RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 2063
+ DSC + +G K + G +++QCD GY + G +TC W+
Sbjct: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
Query: 2064 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF-GVHLQFVNFSTETIH 2122
P C I+ PG S T I+ P+ G +Q+ +
Sbjct: 797 PPFC------------EKIMYCTDPGEVDHS---TRLISDPVLLVGTTIQYTCNPGFVLE 841
Query: 2123 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
+ S ET T P S L E SL + + G+ I+Y+ L
Sbjct: 842 GSSLLTCYSRETGT-------PIWTSRLPHCVSEESLACDNP-GLPENGYQILYKRLYLP 893
Query: 2183 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
G++++F C+ G+ L+G + C+ G +WN PLP C+
Sbjct: 894 --------------------GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 203 bits (517), Expect = 2e-51
Identities = 158/526 (30%), Positives = 246/526 (46%), Gaps = 29/526 (5%)
Query: 1384 GRILSPGYPF-PYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDI-LRVWDGPPENDML 1441
G I S YP P +N L C + + V G V LQ + + + +R DGP L
Sbjct: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPT----L 345
Query: 1442 LKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTR 1499
+ +L+ EG I S N +++ F T F + + + + + C P P +G
Sbjct: 346 TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFPRRPDSGDV 404
Query: 1500 NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSS-GF 1558
G F C GYELQG + +TCI + W P+C APCGG + ++ G
Sbjct: 405 TVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGR 463
Query: 1559 ILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLI-GS 1617
+LSP++P S+ C WTI + L F + D + ++ G + S L+ S
Sbjct: 464 VLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDS 522
Query: 1618 FQDSKLP-ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD 1676
Q +P E + S NT+ + F SD + + + F++ ++A + C++P I NG D
Sbjct: 523 LQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSD 581
Query: 1677 --YKLGSTVTYYCDAGYVL-QGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1733
Y +G+ V + CD G+ L QG + + CI D P WN P C A CG + G V
Sbjct: 582 PTYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVV 639
Query: 1734 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1793
LSPN+P+ Y G +C++ I V +E +F F S D++ +YDG +L G
Sbjct: 640 LSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG 699
Query: 1794 SHSGESLPLSSGNQITIRFTS--VGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG 1851
+SG SS +TI+F S G I KG F+ + + + CS +PE + G +
Sbjct: 700 -NSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTT 758
Query: 1852 N--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1895
+ E G+ + + C+PGY + GS + C+ W+ P C
Sbjct: 759 SHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFC 800
Score = 201 bits (511), Expect = 1e-50
Identities = 203/744 (27%), Positives = 310/744 (41%), Gaps = 87/744 (11%)
Query: 823 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGY-YKDSLNC 881
G + ET T ++ V+ + P A C FS P G I S +P + L C
Sbjct: 252 GSASEESQETTTSTIITTTVITTEQAP---ALCSVSFSNPEGYIDSSDYPLLPLNNFLEC 308
Query: 882 EWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLLGSYNGTQVPQFLFSSSN 939
+ + G+ +++ + + ++L + DGP L +L + Q + S +N
Sbjct: 309 TYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTN 365
Query: 940 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 999
I + F T F++HY++ + SC P P G D G F C G
Sbjct: 366 TISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLG 422
Query: 1000 YRLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPS-GTILSPGYPEFYPNSLNCTW 1055
Y L + L C K HW S P C A CGG V + G +LSP YPE S C W
Sbjct: 423 YELQGAKMLTCINASKPHWSSQE-PICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIW 481
Query: 1056 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTIN-AGLYGNFR 1114
T++ G+ + +F L HD +T + T A L S ++ GL
Sbjct: 482 TIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
Query: 1115 A-QLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFN--FGIGDTLTFSCSSG 1171
++ F SD + + FNI F + C +P I Q G+ + + IG + F+C G
Sbjct: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
Query: 1172 YRLE-GTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYS 1230
+ LE G + I C+ W+ P C A CG + G++LSPN+P Y +CI+
Sbjct: 598 HSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWK 657
Query: 1231 IQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLE 1290
I V K I + + +L+ D+L IYDG + H+LG + G S SST + L ++
Sbjct: 658 IHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPD-LTIQ 716
Query: 1291 FNSDTE----GTDEGFQLVYTSFELS-HCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPG 1344
F+SD G +GF + Y + C D Q G+K + G+ I Y C+PG
Sbjct: 717 FHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
Query: 1345 YTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWM 1404
Y + GS L C + D P I C + + S R++S
Sbjct: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS---------------- 820
Query: 1405 IEVDPGNIV--SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVT 1462
DP +V ++Q+ + + EG S L +
Sbjct: 821 ---DPVLLVGTTIQYTC--------------------------NPGFVLEG-SSLLTCYS 850
Query: 1463 IQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYEL 1520
+ T + S+ + S + AC +PG+P NG + R PG+++ F C G+EL
Sbjct: 851 RETGTPIWTSRLPHCV---SEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFEL 907
Query: 1521 QGEERITCIQVENRYFWQPSPPVC 1544
GE I CI + + W PVC
Sbjct: 908 MGEVTIRCILGQPSH-WNGPLPVC 930
Score = 170 bits (431), Expect = 2e-41
Identities = 183/719 (25%), Positives = 297/719 (41%), Gaps = 98/719 (13%)
Query: 681 CLSNFTAPMGTVLSPDYPEGYGNN-LNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 739
C +F+ P G + S DYP NN L C + + G + L +L S + L+++
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSIRG 339
Query: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 799
D P +L T + S ++ + + F+ F + Y F C P
Sbjct: 340 VDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCNFPRR 398
Query: 800 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH- 858
P + + G C G+ + QG + +TCI K WS P C APCGG
Sbjct: 399 PDSGDVTVMDLHSGGVAHFHCHLGY-ELQGAKMLTCI-NASKPHWSSQEPICSAPCGGAV 456
Query: 859 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 918
+A G +LSP +P S C W IEA G + + FER + D + VH G
Sbjct: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNK 515
Query: 919 SPLL-GSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 976
S LL S VP + L S N I + FT+D +R+ + F I +E+ C +P I
Sbjct: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG--HCYEPYIQ 573
Query: 977 VHGRRYGHD--FSIGSTVSFSCDSGYRLSHEEPLLCE----KNHWWSHPLPTCDALCGGD 1030
+G D ++IG+ V F+CD G+ L + P + E ++ +W+ P C A+CGG+
Sbjct: 574 -NGNFTTSDPTYNIGTIVEFTCDPGHSL-EQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
Query: 1031 VRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT 1090
+ +G +LSP +PE Y +C W + V K + + +L + D L I +
Sbjct: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYD----- 685
Query: 1091 QPLARLTGSDLPPTINAGLYGNFRAQLRFIS--DFSISY------------EGFNITFSE 1136
G ++ P I GN Q + S D +I + +GF + + E
Sbjct: 686 -------GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
Query: 1137 YNL-EPCEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAP 1193
+ + C D Q G + + + G +T+ C GY + G+ + C WS+
Sbjct: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
Query: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV 1253
P C E I+ + P +++ I + G I + G V
Sbjct: 797 PPFC-----------EKIMYCTD-PGEVDHSTRLISDPVLLVGTTIQYTCN-----PGFV 839
Query: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY-TSFELS 1312
L+ G+S+ T +W +L + S E
Sbjct: 840 LE----------------GSSLLTCYSRETGTPIWTS------------RLPHCVSEESL 871
Query: 1313 HCEDPGIPQFGYKI-SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
C++PG+P+ GY+I + + G ++ + C G+ L G ++C+ G+ W+ PLP C
Sbjct: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 134 bits (336), Expect = 2e-30
Identities = 113/418 (27%), Positives = 178/418 (42%), Gaps = 22/418 (5%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P P++G D G F C Y LQGAK +TC ++ WS P+C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH--WSSQEPICSA 450
Query: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 565
G+ G SP++P + + C+W I A K + ++FE L D +T+
Sbjct: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQK-LHLHFERLLLH-DKDRMTV 508
Query: 566 GDGGEVGDPRTVLQVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
G+ + L VP + ++S + + + +D++ + F + ++ EK C
Sbjct: 509 -HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
Query: 625 GDPGTPLYGIREGDGFSN-RDVLRFECQFGFELI-GEKSIVC--QENNQWSANIPICIFP 680
+P D N ++ F C G L G I C + W+ P+C
Sbjct: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM 627
Query: 681 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 740
C +A G VLSP++PE Y +CIW I RI L +L S D L + DG
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYDG 686
Query: 741 DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHS----MSGRGFNITYNTFGHNE-CP 795
D ILG + G P L S++ L ++F +D + G+GF + Y N+ C
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
Query: 796 DPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
D N + + +L G+ I+ C+ G+ G++T+TC + WS P C
Sbjct: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGY-DIVGSDTLTC---QWDLSWSSDPPFC 800
Score = 132 bits (332), Expect = 6e-30
Identities = 175/717 (24%), Positives = 286/717 (39%), Gaps = 84/717 (11%)
Query: 2241 ALCGGNITAMNGTIYSPGYPD-EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITV 2299
ALC + + G I S YP NF +C + V V G G+ + + + +++
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSD-GELLSI 337
Query: 2300 WDGPDQNSPQIGQFSGNTAL---ESVYSTSNQILIKFHSDFTTSGF--FVLSYHAYQLRV 2354
G D P + + T L + + S +N I + F + F G F L Y A+ L
Sbjct: 338 -RGVD--GPTLTVLANQTLLVEGQVIRSPTNTISVYFRT-FQDDGLGTFQLHYQAFMLS- 392
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
C P + ++ D G + + C G+ L G +LTC + P+C
Sbjct: 393 CNFPRRPDSGDVTVMD--LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
Query: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
C + + G +LSP YP++ Q C W+I +G + + E + D + V
Sbjct: 451 PC-GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
Query: 2475 YDGPNIQSPVLISLSGDYSSAFN-ITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCS 2530
+ G +S +L S F + S G+ + +++++D F IR+ AF +C
Sbjct: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
Query: 2531 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQA 2589
P + S + ++V + CD G L G + C Y W+ P C+A
Sbjct: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WNDTEPLCRA 626
Query: 2590 ISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2645
+ CG + G +L+ + Y+ G + + G K + D + N +
Sbjct: 627 M-CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVG---EEKRIFL-----DIQFLNLSN 677
Query: 2646 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTK----VVFSCDPG--YHGLGPASIEC 2699
+ + + IL G++ +G Y + + F DP G G I
Sbjct: 678 SDILTIYDGDEVMPHIL--GQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIM- 734
Query: 2700 LPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVR 2757
N RN+ SC +LP NG K + T G+ + CD G+ +VGS
Sbjct: 735 --NYIEVSRND-------SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTL 785
Query: 2758 ECLSSGLWSESETRC-LAGHCGIP-ELIVNGQVIGENYGYRDTVV-YQCNPGFRLIGSSV 2814
C WS C +C P E+ + ++I + T + Y CNPGF L GSS+
Sbjct: 786 TCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSL 845
Query: 2815 RICQQDHN----WSGQLPSCV---PVSCGHPGSPIYGRTSGNGFNF--------NDVVTF 2859
C W+ +LP CV ++C +PG P NG+ + +TF
Sbjct: 846 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP------ENGYQILYKRLYLPGESLTF 899
Query: 2860 SCNIGYLMQGPTKAQCQANR--QWSHPPPMCKVVNCSDPGI--PANSKRESKIEHGN 2912
C G+ + G +C + W+ P P+CKV S A + E+ +E GN
Sbjct: 900 MCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGN 956
Score = 93.6 bits (231), Expect = 3e-18
Identities = 133/594 (22%), Positives = 216/594 (36%), Gaps = 72/594 (12%)
Query: 2833 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMCKV 2890
+SC P P G + + V F C++GY +QG C + WS P+C
Sbjct: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
Query: 2891 -----VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL-----ICQPN 2940
V+ + G + F T+ + + F +L + +
Sbjct: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
Query: 2941 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 3000
GQ +K ++ D P L E G+T+ T Q+ N
Sbjct: 511 GQTNK---SALLYDSLQTESVPFEGLLSE----GNTIRIEFTSD-----QARAASTFNIR 558
Query: 3001 WSGSQPHCSGDATGTCGDPGTP-GHGSRQESNFRTKSTVRYACDTGYILH-GSEERTCL- 3057
+ + G C +P G+ + + + + V + CD G+ L G C+
Sbjct: 559 FEAFEK-------GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECIN 611
Query: 3058 -ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGY-----ILSGPS 3111
+ W +P C+A+ CG G++ + G S + +EG I G
Sbjct: 612 VRDPYWNDTEPLCRAM-CG-------GELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE 663
Query: 3112 VRQCTANGTWSGTLPNCTIISCGDPGIP-ANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3170
R + + + I GD +P G G+ G Y P T++ +
Sbjct: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHSD 720
Query: 3171 RIRTCTINGTW--SGVMPTCRAVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELS 3226
G + R +C P+I NG T G I+Y C PGY++
Sbjct: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
Query: 3227 FPAVLTCVGNGTWSGEVPQCLP-KFCGDPGIPAQGKR--EGKSFIYQSEVSFSCNFPFIL 3283
LTC + +WS + P C +C DPG R + + + ++CN F+L
Sbjct: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
Query: 3284 VGSSTRICQADGT----WSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFH 3338
GSS C + T W+ PHC+ +C+NPG+P +G Q + G + F
Sbjct: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
Query: 3339 CKKGHLLQGSTTRTCL--PDLTWSGIQPEC------IPHSCKQPETPAHANVVG 3384
C +G L G T C+ W+G P C H+ + E A ++ G
Sbjct: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEG 954
Score = 81.3 bits (199), Expect = 2e-14
Identities = 66/262 (25%), Positives = 115/262 (43%), Gaps = 28/262 (10%)
Query: 25 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD 83
CGG + G + SP +P C W I A E ++ + F+ L ++ D ++++
Sbjct: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHS 510
Query: 84 GHPHPT-----NFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
G + + + +T F + S + + TSD A +A F + +E + C
Sbjct: 511 GQTNKSALLYDSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
Query: 139 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLT-CIANSVNTASWDFPVPICR 196
P + +++G + ++C G+ L+ P + CI +V W+ P+CR
Sbjct: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCR 625
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI-VAEPGDTISLIFTDFQMEEKYDYL 255
A CGG + +G++ SP++P Y DC W I V E IF D Q +L
Sbjct: 626 A--MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE----KRIFLDIQ------FL 673
Query: 256 EIEGSEPPTIWLSGMNIPPPII 277
+ S+ TI+ G + P I+
Sbjct: 674 NLSNSDILTIY-DGDEVMPHIL 694
Score = 76.3 bits (186), Expect = 5e-13
Identities = 114/533 (21%), Positives = 191/533 (35%), Gaps = 87/533 (16%)
Query: 2949 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 3005
+ M+ C P P + ++ G H+ C L G TC +N HWS +
Sbjct: 387 QAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTC-INASKPHWSSQE 445
Query: 3006 PHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGR 3065
P CS G + +T+ Y + + + C+ WT
Sbjct: 446 PICSAPCGGAVHN-----------------ATIGRVLSPSYPENTNGSQFCI----WTIE 484
Query: 3066 QPECKAVQCGNPGTTANGK--VFRIDGTTFSSSVIYSCM-------EGYILSGPSVR--- 3113
PE + + + K + G T S+++Y + EG + G ++R
Sbjct: 485 APEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEF 544
Query: 3114 ---QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVVGQNVSYMCQPGYTMELNG 3169
Q A T++ C +P I D Y +G V + C PG+++E
Sbjct: 545 TSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGP 604
Query: 3170 SRIRTCTINGT-WSGVMPTCRAVT---------CPTPPQISNGRLEGTNFDWGFSIS--- 3216
+ I + W+ P CRA+ P +EG + W +
Sbjct: 605 AIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEK 664
Query: 3217 --YICSPGYELSFPAVLTCVGNGTWSGE--VPQCLPKFCGDPGIPAQGKREGKSFIYQSE 3272
++ LS +LT + G+ +P L ++ G+ G +Y S
Sbjct: 665 RIFLDIQFLNLSNSDILTI-----YDGDEVMPHILGQYLGN---------SGPQKLYSST 710
Query: 3273 VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT-SCENPGVPRHGSQNNTFGFQV 3331
+ F G G G + IE ++ SC + ++G + + V
Sbjct: 711 PDLTIQFHSDPAGLIF------GKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELV 764
Query: 3332 -GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC--IPHSCKQPETPAHANVVGMDLP 3388
G+ + + C G+ + GS T TC DL+WS P C I + E ++ +
Sbjct: 765 RGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVL 824
Query: 3389 SHGYTLIYTCQPGFFLAGGTEHRVCRSDNT----WTGKVPICEAGSKILVKDP 3437
G T+ YTC PGF L G+ C S T WT ++P C + + +P
Sbjct: 825 LVGTTIQYTCNPGFVLE-GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
Score = 70.1 bits (170), Expect = 4e-11
Identities = 109/455 (23%), Positives = 162/455 (35%), Gaps = 102/455 (22%)
Query: 126 FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNT 185
F+++Y+ S C P P G + G + C GY L G LTCI + +
Sbjct: 382 FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASK 438
Query: 186 ASWDFPVPICRAEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFT 244
W PIC A CGG + ++ G + SPS+P + + C WTI A G + L F
Sbjct: 439 PHWSSQEPICSA--PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFE 496
Query: 245 DFQMEEK----------------YDYLEIEG-------SEPPTIWL----------SGMN 271
+ +K YD L+ E SE TI + S N
Sbjct: 497 RLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFN 556
Query: 272 IP----------PPIISNKNWLR----------LHFVTDSNHRYRGFSA---------PY 302
I P I N N+ + F D H A PY
Sbjct: 557 IRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY 616
Query: 303 -QGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQR----VQ 357
+ L GEL G + + P IH + EE+R +Q
Sbjct: 617 WNDTEPLCRAMCGGELS----AVAGVVLSPNWPEPYVEGEDCIWKIH-VGEEKRIFLDIQ 671
Query: 358 VTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDF-KS 416
+L NS + D + PH P+ + T +L + H + F K
Sbjct: 672 FLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKG 729
Query: 417 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSCDE 474
+GF I+N + + ++ C D E +NG + S L G+ + + CD
Sbjct: 730 QGF-------------IMNYIEV-SRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDP 775
Query: 475 DYVLQGAKSITCQRIAEVFAAWSDHRPVC-KVKTC 508
Y + G+ ++TCQ +WS P C K+ C
Sbjct: 776 GYDIVGSDTLTCQ----WDLSWSSDPPFCEKIMYC 806
Score = 70.1 bits (170), Expect = 4e-11
Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2799 VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS-CGHPGSPIYGR--TSGNGFNFND 2855
+ YQC+PG+ ++GS CQ D +WS P C + C PG + S
Sbjct: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
Query: 2856 VVTFSCNIGYLMQGPTKAQCQANRQ----WSHPPPMC---KVVNCSDPGIPANSKRESKI 2908
+ ++CN G++++G + C + W+ P C + + C +PG+P N + +
Sbjct: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQ--IL 886
Query: 2909 EHGNFTYGTVVFYDCNPGYFLFGSSVLIC---QPNGQWDKPLPEC 2950
+ G + + C G+ L G + C QP+ W+ PLP C
Sbjct: 887 YKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS-HWNGPLPVC 930
Score = 62.4 bits (150), Expect = 8e-09
Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 14/200 (7%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L + G + SP +P Y G +C W I E RI + Q L D L++YDG
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA----VSAHGFKVYYEEL-QSSSCG 139
+ + G P + S+ +++ SD A GF + Y E+ ++ SC
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
Query: 140 NPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
+ G T G +I Y C GY + G LTC + SW P C
Sbjct: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEK 802
Query: 198 EDAC--GGTMRGSSGIISSP 215
C G + S+ +IS P
Sbjct: 803 IMYCTDPGEVDHSTRLISDP 822
Score = 45.4 bits (106), Expect = 0.001
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C DPGE ++ R+ SD +G+T+Q++C+ +VL+G+ +TC W+ P C
Sbjct: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 134 QSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 191
+S +C NPG+P G +LY + G+ + + C G+ L G + CI + W+ P
Sbjct: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILG--QPSHWNGP 926
Query: 192 VPICR 196
+P+C+
Sbjct: 927 LPVCK 931
Score = 40.0 bits (92), Expect = 0.043
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 156 VGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
VG I+Y+C G++L+G LTC + T W +P C +E++
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEES 870
Score = 37.4 bits (85), Expect = 0.28
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 439 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 496
+ S C +PG PENG +I + G ++ F C E + L G +I C I + W
Sbjct: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHW 923
Query: 497 SDHRPVCKV 505
+ PVCKV
Sbjct: 924 NGPLPVCKV 932
Score = 35.4 bits (80), Expect = 1.0
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 620 EKESCGDPGTPL--YGIREGDGFSNRDVLRFECQFGFELIGEKSIVC--QENNQWSANIP 675
E +C +PG P Y I + + L F C GFEL+GE +I C + + W+ +P
Sbjct: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLP 928
Query: 676 IC 677
+C
Sbjct: 929 VC 930
Score = 33.5 bits (75), Expect = 4.0
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 1857 GSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1897
G S+ F C G+ L G + IRC + + WN LP C V
Sbjct: 894 GESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 233 bits (594), Expect = 3e-60
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 1898 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1956
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 1957 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 2015
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 2016 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2075
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 2076 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2133
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 2134 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2192
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 2193 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2250
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 2251 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2310
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
Query: 2311 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2364
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
Query: 2365 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2398
E G ++ YQC PG+ +VG+++L C+
Sbjct: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
Score = 224 bits (570), Expect = 2e-57
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 1155 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1214
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
Query: 1215 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1273
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
Query: 1274 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1332
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
Query: 1333 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1392
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
Query: 1393 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1447
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Query: 1448 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1506
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1507 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1565
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1566 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1625
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1626 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1679
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1680 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1734
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1735 SPNYPKNYSVGHNC 1748
SP +P +V + C
Sbjct: 786 SPKFPVGATVQYIC 799
Score = 219 bits (559), Expect = 3e-56
Identities = 182/653 (27%), Positives = 289/653 (44%), Gaps = 51/653 (7%)
Query: 2095 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2149
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
Query: 2150 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2202
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
Query: 2203 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2261
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 2262 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2319
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 2320 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2378
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
Query: 2379 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2437
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
Query: 2438 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2497
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Query: 2498 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2548
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
Query: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2605
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
Query: 2606 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHG 2665
+ VG V Y C+ G+ L + T + G+ ++ P+C++ +
Sbjct: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
Query: 2666 RWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2718
R + + FSC PGY G ASI+C+P W + P C+ S
Sbjct: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 206 bits (525), Expect = 3e-52
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 854 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 911
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 912 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 970
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
Query: 971 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 1028
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 1029 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1087
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 1088 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1147
+ P + I L + +D S + G + + + C +P +
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
Query: 1148 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1204
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
Query: 1205 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1264
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
Query: 1265 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1321
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
Query: 1322 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1376
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
Query: 1377 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
E S R++S P +P C D G ++ + HD R P
Sbjct: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
Query: 1436 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
+D K + L P C P
Sbjct: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
Query: 1496 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1546
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
Score = 190 bits (482), Expect = 3e-47
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 508 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
Query: 567 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 682
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 683 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 742 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 798
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
Query: 799 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
Query: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 917
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
Query: 918 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 973
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
Query: 974 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 1028
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
Query: 1029 GDVRGPSGTILSPGYP 1044
GDV I SP +P
Sbjct: 775 GDVEHSRRLISSPKFP 790
Score = 184 bits (467), Expect = 1e-45
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 680 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 738
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
Query: 739 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 797
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
Query: 798 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
Query: 858 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 916
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 917 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 974
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
Query: 975 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 1025
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
Query: 1026 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1085
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
Query: 1086 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1139
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
Query: 1140 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
Query: 1198 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1256
+ S + P + E++ I S + G + I + F L +L
Sbjct: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
Query: 1257 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1316
+D + + S + + LE +L C
Sbjct: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
Query: 1317 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 183 bits (465), Expect = 2e-45
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 1547 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
Query: 1606 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1663
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
Query: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1723
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
Query: 1724 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1776
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
Query: 1777 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
Query: 1833 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1889
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
Query: 1890 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1949
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
Query: 1950 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 2009
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
Query: 2010 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2062
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
Query: 2063 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2118
+P C + C G + +I SP FP C GF + S
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
Query: 2119 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
T HD ++GS + S P+ H S + S KQ H
Sbjct: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
Query: 2179 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
Query: 2239 CEA 2241
C A
Sbjct: 895 CRA 897
Score = 137 bits (344), Expect = 3e-31
Identities = 179/771 (23%), Positives = 289/771 (37%), Gaps = 136/771 (17%)
Query: 307 TLTHTTSTGELEEHNRTTTGAIAVAST--------------------------PADVTVS 340
T+T +T++G+ EE TTT +T P DV +
Sbjct: 211 TITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLD 270
Query: 341 SVTAVTIHR-LSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTK 399
++++ E +VQ SLR G P P QS R Q+ R+
Sbjct: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRG----QVIRSP 326
Query: 400 ELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIG 459
TH+ A+ F+S PG + + + L C P P G
Sbjct: 327 -----THQA--ALRFQSLPPPAGPGTFHFHYQAYLLS---------CHFPRRPAYGDVTV 370
Query: 460 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GT 518
+ G + +F C Y L+GA+ +TC + F W PVC + CG ++ + G
Sbjct: 371 TSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGR 427
Query: 519 FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVL 578
SP FP Y +N C W++ A + + ++FE+ L D L I +G V P V
Sbjct: 428 IVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVY 485
Query: 579 QVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDP---------G 628
++P + ++S ++ L TD S + G + Y+ ++ C +P
Sbjct: 486 DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSS 545
Query: 629 TPLYGIREGDGFSNRDVLRFECQFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNF 685
TP Y + + F C G+ L G I C + + QW+ P C C
Sbjct: 546 TPTYPV--------GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI 597
Query: 686 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 745
T G VLSP++PE YG +CIW + + RI L + D L DGD +
Sbjct: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTA 656
Query: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGI 799
+LG ++G L ++ + ++FQ+D S +GF I + N+ CP+ P I
Sbjct: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
Query: 800 PINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
P N + +L G+ ++ C G+ + G+ + C + WS +P C
Sbjct: 717 P-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSC 771
Query: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 917
H PG + S + G +++ ++ + +L HD
Sbjct: 772 HD------------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ-- 817
Query: 918 LSPLLGSYN-GTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 976
GS + P+ L + L +N + ++H T++
Sbjct: 818 ----AGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH---------- 863
Query: 977 VHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNH--WWSHPLPTCDA 1025
FSC GY L + + C H WS P P C A
Sbjct: 864 -----------------FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 102 bits (254), Expect = 7e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 2243 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2298
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
Query: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2356
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
Query: 2357 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2416
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
Query: 2417 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2476
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2477 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2532
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 2533 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2592
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
Query: 2593 G 2593
G
Sbjct: 595 G 595
Score = 99.0 bits (245), Expect = 8e-20
Identities = 66/225 (29%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Query: 22 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 80
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
Query: 81 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
Query: 139 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 196
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 241
A C G + S+G++ SP++P Y DC W + E I L
Sbjct: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML 633
Score = 95.9 bits (237), Expect = 7e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 3015 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 3069
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
Query: 3070 -----------KAVQCGNPGTTANG-----------------------------KVFRID 3089
+ V G PG +N ++ +
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 3090 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3139
G + +Y +EG + SG ++G +G G P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 3140 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3191
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
Query: 3192 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3228
C S G + N+ WG + PG L+F
Sbjct: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 3229 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3264
LT G +SG + +F DPG G ++G
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 3265 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3310
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
Query: 3311 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3365
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3366 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3418
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 3419 WTGKVPICEAGS 3430
W+ PIC A S
Sbjct: 888 WSDPPPICRAAS 899
Score = 95.1 bits (235), Expect = 1e-18
Identities = 138/570 (24%), Positives = 204/570 (35%), Gaps = 115/570 (20%)
Query: 2590 ISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2649
+SC P+ P G + T G + C GY+L T + + W + K P C
Sbjct: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDS--KEPVC 412
Query: 2650 VVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRN 2709
+ C + I RIV+ PG+ G ++ C W
Sbjct: 413 IAA-CGGV---IRNATTGRIVS---------------PGFPGNYSNNLTC------HWLL 447
Query: 2710 ERP-------YCQIISCGELPTP---PNGNKIGTQTSYGSTAIFTCDL-GFMLVGSAVRE 2758
E P + + +S E NG+ + Y S + + G + G
Sbjct: 448 EAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFV 507
Query: 2759 CLS---SGLWSESETRCLA---GHCGIPELIV-NGQVIGENYGYRDTVVYQCNPGFRLIG 2811
LS SG + R A GHC P + N Y TV + C+PG+ L
Sbjct: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ 567
Query: 2812 SSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPIYGRTSGNG------FNFND 2855
S+ I C H+ W+ P+C V S G SP + G G + +
Sbjct: 568 GSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEE 627
Query: 2856 VVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPMCKVVNC---------SDPG 2897
+I L GP + Q+S P K+ SDPG
Sbjct: 628 DKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPG 687
Query: 2898 ----------------IPANSKRESKIEHGN---------FTYGTVVFYDCNPGYFLFGS 2932
+P N E N +GTVV Y C PGY + GS
Sbjct: 688 TSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGS 747
Query: 2933 SVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLG 2989
SVL+CQ + W + LP C + C PG ++ ++S K+ G+TV Y C L+G
Sbjct: 748 SVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMG 807
Query: 2990 QSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGSR--QESNFRTKSTVRYACD 3043
S TC + WS P C + C P +G+R ++ +T+ ++C
Sbjct: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCA 867
Query: 3044 TGYILHGSEERTCLAN--GSWTGRQPECKA 3071
GY+L G C+ W+ P C+A
Sbjct: 868 PGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 86.7 bits (213), Expect = 4e-16
Identities = 153/607 (25%), Positives = 217/607 (35%), Gaps = 141/607 (23%)
Query: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
++SC P G+ T G +A F C G+ L G+ CL++ W E C+
Sbjct: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
Query: 2774 AGHCGIPELIVNGQVIGENY--GYRDTV----VYQCNPGFR--LIGSSVRICQQDHNW-- 2823
A G+ G+++ + Y + + + + G R L V + + D
Sbjct: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
Query: 2824 -SGQLPSCVPVSCGHPGS--PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
+G PV + PI G S F ++ T S M +A Q
Sbjct: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--- 530
Query: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF-----TY--GTVVFYDCNPGYFLFGSS 2933
+C +P +++GNF TY GT V + C+PGY L S
Sbjct: 531 -----------HCYEP----------FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGS 569
Query: 2934 VLI--CQPNG-QWDKPLPECIMIDCGHPGVPPNAVLS---GEKYTFGST----VHYSCTG 2983
++I P+ QW++ P C + G VLS E Y G VH
Sbjct: 570 IIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE-ED 628
Query: 2984 KRSLL----------------GQSSRTCQLNGHWSGSQPH-----CSGDAT-GTCGDPGT 3021
KR +L T ++ G +SG + H D T DPGT
Sbjct: 629 KRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGT 688
Query: 3022 PGHGSRQESNFRTKSTVRYACDTGYILHGSE---ERTC-----LANGSWTGRQPECKAVQ 3073
G +Q G+++H E TC + NG + QPE
Sbjct: 689 SVLGYQQ----------------GFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL---- 728
Query: 3074 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIIS 3132
+ GT V Y C GY + G SV C + TWS LP+C + S
Sbjct: 729 --------------VHGTV----VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS 770
Query: 3133 CGDPGIPANGLRY--GDDYVVGQNVSYMCQPGYTMELNGSRIRTC----TINGTWSGVMP 3186
C DPG + R + VG V Y+C G+ L GS I TC + WS P
Sbjct: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV--LMGSSILTCHDRQAGSPKWSDRAP 828
Query: 3187 TC---RAVTCPTPPQISNGRL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTW 3239
C + C NG E G +I + C+PGY L A + CV W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 3240 SGEVPQC 3246
S P C
Sbjct: 889 SDPPPIC 895
Score = 79.3 bits (194), Expect = 6e-14
Identities = 79/291 (27%), Positives = 114/291 (39%), Gaps = 21/291 (7%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 83 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
G P P N L G + P +LR S + G ++ + SC
Sbjct: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
Query: 200 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 259 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
+ PP + P ++S+ + TDS+ G + Y+
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE 525
Score = 74.7 bits (182), Expect = 2e-12
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 2718 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2774
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 2775 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH----NWSGQLP 2828
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 2829 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2881
C+ C +P G S + FSC GY+++G +C W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 2882 SHPPPMCKVVN 2892
S PPP+C+ +
Sbjct: 889 SDPPPICRAAS 899
Score = 58.5 bits (140), Expect = 1e-07
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 14/203 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
C G + G + SP +P Y G +C W + EE RI + + + D L+ YDG
Sbjct: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDG 651
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-----YYEELQSSSCG 139
+ +G + ++ + +++ SD S G++ ++E ++ +C
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
P G ++ ++ G + Y C GY + G L C + +W +P C+
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDLPSCQR 767
Query: 198 EDAC--GGTMRGSSGIISSPSFP 218
+C G + S +ISSP FP
Sbjct: 768 VTSCHDPGDVEHSRRLISSPKFP 790
Score = 39.3 bits (90), Expect = 0.073
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 157 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 216
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
Score = 37.7 bits (86), Expect = 0.21
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 136 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 193
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 194 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 236
C E C G +G S P + + A T PG
Sbjct: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 233 bits (594), Expect = 3e-60
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 1898 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1956
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 1957 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 2015
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 2016 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2075
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 2076 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2133
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 2134 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2192
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 2193 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2250
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 2251 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2310
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
Query: 2311 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2364
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
Query: 2365 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2398
E G ++ YQC PG+ +VG+++L C+
Sbjct: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
Score = 224 bits (570), Expect = 2e-57
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 1155 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1214
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
Query: 1215 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1273
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
Query: 1274 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1332
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
Query: 1333 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1392
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
Query: 1393 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1447
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Query: 1448 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1506
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1507 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1565
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1566 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1625
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1626 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1679
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1680 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1734
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1735 SPNYPKNYSVGHNC 1748
SP +P +V + C
Sbjct: 786 SPKFPVGATVQYIC 799
Score = 219 bits (559), Expect = 3e-56
Identities = 182/653 (27%), Positives = 289/653 (44%), Gaps = 51/653 (7%)
Query: 2095 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2149
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
Query: 2150 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2202
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
Query: 2203 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2261
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 2262 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2319
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 2320 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2378
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
Query: 2379 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2437
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
Query: 2438 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2497
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Query: 2498 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2548
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
Query: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2605
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
Query: 2606 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHG 2665
+ VG V Y C+ G+ L + T + G+ ++ P+C++ +
Sbjct: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
Query: 2666 RWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2718
R + + FSC PGY G ASI+C+P W + P C+ S
Sbjct: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 206 bits (525), Expect = 3e-52
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 854 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 911
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 912 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 970
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
Query: 971 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 1028
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 1029 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1087
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 1088 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1147
+ P + I L + +D S + G + + + C +P +
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
Query: 1148 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1204
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
Query: 1205 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1264
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
Query: 1265 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1321
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
Query: 1322 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1376
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
Query: 1377 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
E S R++S P +P C D G ++ + HD R P
Sbjct: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
Query: 1436 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
+D K + L P C P
Sbjct: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
Query: 1496 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1546
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
Score = 190 bits (482), Expect = 3e-47
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 508 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
Query: 567 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 682
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 683 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 742 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 798
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
Query: 799 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
Query: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 917
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
Query: 918 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 973
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
Query: 974 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 1028
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
Query: 1029 GDVRGPSGTILSPGYP 1044
GDV I SP +P
Sbjct: 775 GDVEHSRRLISSPKFP 790
Score = 184 bits (467), Expect = 1e-45
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 680 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 738
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
Query: 739 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 797
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
Query: 798 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
Query: 858 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 916
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 917 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 974
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
Query: 975 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 1025
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
Query: 1026 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1085
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
Query: 1086 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1139
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
Query: 1140 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
Query: 1198 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1256
+ S + P + E++ I S + G + I + F L +L
Sbjct: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
Query: 1257 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1316
+D + + S + + LE +L C
Sbjct: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
Query: 1317 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 183 bits (465), Expect = 2e-45
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 1547 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
Query: 1606 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1663
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
Query: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1723
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
Query: 1724 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1776
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
Query: 1777 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
Query: 1833 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1889
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
Query: 1890 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1949
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
Query: 1950 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 2009
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
Query: 2010 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2062
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
Query: 2063 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2118
+P C + C G + +I SP FP C GF + S
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
Query: 2119 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
T HD ++GS + S P+ H S + S KQ H
Sbjct: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
Query: 2179 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
Query: 2239 CEA 2241
C A
Sbjct: 895 CRA 897
Score = 137 bits (344), Expect = 3e-31
Identities = 179/771 (23%), Positives = 289/771 (37%), Gaps = 136/771 (17%)
Query: 307 TLTHTTSTGELEEHNRTTTGAIAVAST--------------------------PADVTVS 340
T+T +T++G+ EE TTT +T P DV +
Sbjct: 211 TITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLD 270
Query: 341 SVTAVTIHR-LSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTK 399
++++ E +VQ SLR G P P QS R Q+ R+
Sbjct: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRG----QVIRSP 326
Query: 400 ELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIG 459
TH+ A+ F+S PG + + + L C P P G
Sbjct: 327 -----THQA--ALRFQSLPPPAGPGTFHFHYQAYLLS---------CHFPRRPAYGDVTV 370
Query: 460 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GT 518
+ G + +F C Y L+GA+ +TC + F W PVC + CG ++ + G
Sbjct: 371 TSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGR 427
Query: 519 FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVL 578
SP FP Y +N C W++ A + + ++FE+ L D L I +G V P V
Sbjct: 428 IVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVY 485
Query: 579 QVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDP---------G 628
++P + ++S ++ L TD S + G + Y+ ++ C +P
Sbjct: 486 DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSS 545
Query: 629 TPLYGIREGDGFSNRDVLRFECQFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNF 685
TP Y + + F C G+ L G I C + + QW+ P C C
Sbjct: 546 TPTYPV--------GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI 597
Query: 686 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 745
T G VLSP++PE YG +CIW + + RI L + D L DGD +
Sbjct: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTA 656
Query: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGI 799
+LG ++G L ++ + ++FQ+D S +GF I + N+ CP+ P I
Sbjct: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
Query: 800 PINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
P N + +L G+ ++ C G+ + G+ + C + WS +P C
Sbjct: 717 P-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSC 771
Query: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 917
H PG + S + G +++ ++ + +L HD
Sbjct: 772 HD------------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ-- 817
Query: 918 LSPLLGSYN-GTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 976
GS + P+ L + L +N + ++H T++
Sbjct: 818 ----AGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH---------- 863
Query: 977 VHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNH--WWSHPLPTCDA 1025
FSC GY L + + C H WS P P C A
Sbjct: 864 -----------------FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 102 bits (254), Expect = 7e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 2243 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2298
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
Query: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2356
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
Query: 2357 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2416
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
Query: 2417 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2476
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2477 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2532
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 2533 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2592
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
Query: 2593 G 2593
G
Sbjct: 595 G 595
Score = 99.0 bits (245), Expect = 8e-20
Identities = 66/225 (29%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Query: 22 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 80
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
Query: 81 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
Query: 139 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 196
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 241
A C G + S+G++ SP++P Y DC W + E I L
Sbjct: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML 633
Score = 95.9 bits (237), Expect = 7e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 3015 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 3069
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
Query: 3070 -----------KAVQCGNPGTTANG-----------------------------KVFRID 3089
+ V G PG +N ++ +
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 3090 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3139
G + +Y +EG + SG ++G +G G P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 3140 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3191
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
Query: 3192 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3228
C S G + N+ WG + PG L+F
Sbjct: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 3229 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3264
LT G +SG + +F DPG G ++G
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 3265 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3310
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
Query: 3311 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3365
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3366 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3418
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 3419 WTGKVPICEAGS 3430
W+ PIC A S
Sbjct: 888 WSDPPPICRAAS 899
Score = 95.1 bits (235), Expect = 1e-18
Identities = 138/570 (24%), Positives = 204/570 (35%), Gaps = 115/570 (20%)
Query: 2590 ISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2649
+SC P+ P G + T G + C GY+L T + + W + K P C
Sbjct: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDS--KEPVC 412
Query: 2650 VVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRN 2709
+ C + I RIV+ PG+ G ++ C W
Sbjct: 413 IAA-CGGV---IRNATTGRIVS---------------PGFPGNYSNNLTC------HWLL 447
Query: 2710 ERP-------YCQIISCGELPTP---PNGNKIGTQTSYGSTAIFTCDL-GFMLVGSAVRE 2758
E P + + +S E NG+ + Y S + + G + G
Sbjct: 448 EAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFV 507
Query: 2759 CLS---SGLWSESETRCLA---GHCGIPELIV-NGQVIGENYGYRDTVVYQCNPGFRLIG 2811
LS SG + R A GHC P + N Y TV + C+PG+ L
Sbjct: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ 567
Query: 2812 SSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPIYGRTSGNG------FNFND 2855
S+ I C H+ W+ P+C V S G SP + G G + +
Sbjct: 568 GSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEE 627
Query: 2856 VVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPMCKVVNC---------SDPG 2897
+I L GP + Q+S P K+ SDPG
Sbjct: 628 DKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPG 687
Query: 2898 ----------------IPANSKRESKIEHGN---------FTYGTVVFYDCNPGYFLFGS 2932
+P N E N +GTVV Y C PGY + GS
Sbjct: 688 TSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGS 747
Query: 2933 SVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLG 2989
SVL+CQ + W + LP C + C PG ++ ++S K+ G+TV Y C L+G
Sbjct: 748 SVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMG 807
Query: 2990 QSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGSR--QESNFRTKSTVRYACD 3043
S TC + WS P C + C P +G+R ++ +T+ ++C
Sbjct: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCA 867
Query: 3044 TGYILHGSEERTCLAN--GSWTGRQPECKA 3071
GY+L G C+ W+ P C+A
Sbjct: 868 PGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 86.7 bits (213), Expect = 4e-16
Identities = 153/607 (25%), Positives = 217/607 (35%), Gaps = 141/607 (23%)
Query: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
++SC P G+ T G +A F C G+ L G+ CL++ W E C+
Sbjct: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
Query: 2774 AGHCGIPELIVNGQVIGENY--GYRDTV----VYQCNPGFR--LIGSSVRICQQDHNW-- 2823
A G+ G+++ + Y + + + + G R L V + + D
Sbjct: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
Query: 2824 -SGQLPSCVPVSCGHPGS--PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
+G PV + PI G S F ++ T S M +A Q
Sbjct: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--- 530
Query: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF-----TY--GTVVFYDCNPGYFLFGSS 2933
+C +P +++GNF TY GT V + C+PGY L S
Sbjct: 531 -----------HCYEP----------FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGS 569
Query: 2934 VLI--CQPNG-QWDKPLPECIMIDCGHPGVPPNAVLS---GEKYTFGST----VHYSCTG 2983
++I P+ QW++ P C + G VLS E Y G VH
Sbjct: 570 IIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE-ED 628
Query: 2984 KRSLL----------------GQSSRTCQLNGHWSGSQPH-----CSGDAT-GTCGDPGT 3021
KR +L T ++ G +SG + H D T DPGT
Sbjct: 629 KRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGT 688
Query: 3022 PGHGSRQESNFRTKSTVRYACDTGYILHGSE---ERTC-----LANGSWTGRQPECKAVQ 3073
G +Q G+++H E TC + NG + QPE
Sbjct: 689 SVLGYQQ----------------GFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL---- 728
Query: 3074 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIIS 3132
+ GT V Y C GY + G SV C + TWS LP+C + S
Sbjct: 729 --------------VHGTV----VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS 770
Query: 3133 CGDPGIPANGLRY--GDDYVVGQNVSYMCQPGYTMELNGSRIRTC----TINGTWSGVMP 3186
C DPG + R + VG V Y+C G+ L GS I TC + WS P
Sbjct: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV--LMGSSILTCHDRQAGSPKWSDRAP 828
Query: 3187 TC---RAVTCPTPPQISNGRL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTW 3239
C + C NG E G +I + C+PGY L A + CV W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 3240 SGEVPQC 3246
S P C
Sbjct: 889 SDPPPIC 895
Score = 79.3 bits (194), Expect = 6e-14
Identities = 79/291 (27%), Positives = 114/291 (39%), Gaps = 21/291 (7%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 83 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
G P P N L G + P +LR S + G ++ + SC
Sbjct: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
Query: 200 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 259 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
+ PP + P ++S+ + TDS+ G + Y+
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE 525
Score = 74.7 bits (182), Expect = 2e-12
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 2718 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2774
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 2775 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH----NWSGQLP 2828
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 2829 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2881
C+ C +P G S + FSC GY+++G +C W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 2882 SHPPPMCKVVN 2892
S PPP+C+ +
Sbjct: 889 SDPPPICRAAS 899
Score = 58.5 bits (140), Expect = 1e-07
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 14/203 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
C G + G + SP +P Y G +C W + EE RI + + + D L+ YDG
Sbjct: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDG 651
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-----YYEELQSSSCG 139
+ +G + ++ + +++ SD S G++ ++E ++ +C
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
P G ++ ++ G + Y C GY + G L C + +W +P C+
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDLPSCQR 767
Query: 198 EDAC--GGTMRGSSGIISSPSFP 218
+C G + S +ISSP FP
Sbjct: 768 VTSCHDPGDVEHSRRLISSPKFP 790
Score = 39.3 bits (90), Expect = 0.073
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 157 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 216
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
Score = 37.7 bits (86), Expect = 0.21
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 136 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 193
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 194 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 236
C E C G +G S P + + A T PG
Sbjct: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 [Homo
sapiens]
Length = 840
Score = 224 bits (570), Expect = 2e-57
Identities = 181/670 (27%), Positives = 291/670 (43%), Gaps = 36/670 (5%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSL---DCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2127
C +S+ G + SP +L DCT++I++ G+G+ +Q + + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2128 RSGSSE--TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2185
G S ++ S L S T+ L+F S GF I YQAY L
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGF 222
Query: 2186 DPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGG 2245
PRP +G V D G T +F C GY L G L CL+G +WN P C A CGG
Sbjct: 223 PPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGG 281
Query: 2246 NI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPD 2304
I A G I SP C W++ G ++++F + + D + V G
Sbjct: 282 TIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGS 341
Query: 2305 QNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRVCQPPPPVP 2362
SP I + E + S + + ++ S+ + + L + A++ C P +
Sbjct: 342 PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF-LA 400
Query: 2363 NAEILTEDDEFEIGDIIRYQCLPGFTLVG----NAILTCRLGERLQMDGAPPVCQVLCPA 2418
+ + T D E+ G + + CLPG+ L NAI C + P C+ +C
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEPACKAMC-G 458
Query: 2419 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2478
EL + GV+LSP +P SY Q C W + V++ I + VE +E D+L ++DG
Sbjct: 459 GELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGDMLTLFDGD 516
Query: 2479 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPES---- 2534
+ VL L G + S+G ++ LQ+ A G G ++ + P +
Sbjct: 517 GPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 575
Query: 2535 ---PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2589
PP + + G L +V+ + C+ G+ L+G C+ +W A PACQ
Sbjct: 576 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWSAAPPACQK 631
Query: 2590 I-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2646
I +C P NG +D + VG+ V Y C GY L + T + GT ++
Sbjct: 632 IMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV 691
Query: 2647 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2706
P+C + P +N + E+G ++ + HY+ + F C G+ +G +I C+P
Sbjct: 692 PKCALKYEPCLNPGVPENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ 750
Query: 2707 WRNERPYCQI 2716
W ++ P C++
Sbjct: 751 WTSQPPLCKV 760
Score = 212 bits (540), Expect = 5e-54
Identities = 194/740 (26%), Positives = 292/740 (39%), Gaps = 79/740 (10%)
Query: 1894 TCIVPCGGILTKRKGTILSPGYPEPYDNNL---NCVWKITVPEGAGIQVQVVSFATEHNW 1950
T V C +++ +G + SP P L +C + I V G GI++QV +
Sbjct: 98 TSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEE 157
Query: 1951 DSLDFYDGGDNN-APRLGSYSGTTIP-HLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIG 2008
+ L GG APRL + S +L S +N L L+FQS GF + Y A
Sbjct: 158 ELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYL 217
Query: 2009 LDSCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2067
L SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C
Sbjct: 218 L-SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 2068 LAQCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE 2126
+A CGG + + + G I+SP G +L C W I G +HL F S + +D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 2127 VRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2185
VRSG S S VI +P L S + S+ N + ++A++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 2186 DPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCE 2240
P +G V D + G +F C PGY L +A+ C+ +WN P C+
Sbjct: 396 APF-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 454
Query: 2241 ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2300
A+CGG ++ G + SP +P Y QDC W V V I + +L D +T++
Sbjct: 455 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLF 513
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRV 2354
DG ++ + Q G + S+ + ++F + GF + +
Sbjct: 514 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 573
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
C PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ- 630
Query: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
+ CA + G+ ++ F V
Sbjct: 631 -------------------------KIMTCADPGEIANGHRTA-------SDAGFPV--- 655
Query: 2475 YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CST 2531
G ++Q Y + G + +S D G K R+ A C
Sbjct: 656 --GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLN 703
Query: 2532 PESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2590
P P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 704 PGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCKVT 761
Query: 2591 SCGIPKAPTNGGILTTDYLV 2610
P GG L L+
Sbjct: 762 QTTDPSRQLEGGNLALAILL 781
Score = 207 bits (528), Expect = 1e-52
Identities = 186/714 (26%), Positives = 298/714 (41%), Gaps = 82/714 (11%)
Query: 855 CGGHFSAPSGVILSPGWPGYYKDSL---NCEWVIEAEPGHSIKITFERFQTELNYDVLEV 911
C + S G + SP +L +C + I PG+ I+I + ++L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 912 HDG--PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYS 969
G P L LL + + Q L S +N + L F + GF+IHY++ + S
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL---S 219
Query: 970 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDALC 1027
C P P HG D G T +F CDSGY+L EE L+C W+ P+C A C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 279
Query: 1028 GGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1086
GG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 1087 GSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCEDP 1145
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C P
Sbjct: 340 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 397
Query: 1146 GIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAEC 1201
+ + + G TFSC GY LE + I C+ W+ P C A C
Sbjct: 398 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 457
Query: 1202 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1261
G + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 458 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 517
Query: 1262 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CED 1316
+ +L G R LSS L L+F + G +GF L + + C +
Sbjct: 518 PSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 576
Query: 1317 PGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAE 1373
P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 577 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMT 634
Query: 1374 CGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVW 1432
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT---- 682
Query: 1433 DGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPG 1492
P +D + K A+++ C +PG
Sbjct: 683 GTPKWSDRVPK--------------------------------CALKYE-----PCLNPG 705
Query: 1493 VPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
VP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 706 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 758
Score = 206 bits (524), Expect = 3e-52
Identities = 190/781 (24%), Positives = 318/781 (40%), Gaps = 96/781 (12%)
Query: 1381 ESSGRILSPGYPFPYDNNLR---CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1437
E G + SP P L C + I V PG + +Q + ++L + G
Sbjct: 109 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 168
Query: 1438 NDMLLKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
+ S++ EG + S N + + F + GF I + + + + C P P
Sbjct: 169 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPA 227
Query: 1496 NGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGS 1555
+G + PG T F CD GY+LQGEE + C+ R W P C+A CGG + +
Sbjct: 228 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 286
Query: 1556 S-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPL 1614
+ G I+SP + C W I + L F S++ + D L + G SP+
Sbjct: 287 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 346
Query: 1615 IGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP----GNIMN 1669
I +PER + S + ++++ S+ + L ++A + CF P GN+
Sbjct: 347 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV-- 404
Query: 1670 GTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGWNRALPSCHAPCGSRS 1726
T +Y+ G+ T+ C GY L+ + + C+ D P WN P+C A CG
Sbjct: 405 -TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACKAMCGGEL 461
Query: 1727 TGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS 1786
+ G VLSP++P++YS G +CV+ + V +E + Q D++ ++DG +
Sbjct: 462 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSAR 521
Query: 1787 LLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVYQAVPRTSSTQCSSVP 1842
+L+ L G L LSSG +T++F + P +GF ++ VPR + C +P
Sbjct: 522 VLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELP 578
Query: 1843 EPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1900
P +G R + + G+ + + C PGY L GS + C QW+ S C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--------QWDLSWSAAPPACQ 630
Query: 1901 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSLDFYDGG 1959
I+T ++ G+ D P G+ +Q + + ++ E
Sbjct: 631 KIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGYSLE------------ 670
Query: 1960 DNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPS 2019
A L YS D + A+ + C P P
Sbjct: 671 --GAAMLTCYS--------------------RDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 2020 SGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMS 2076
+G + Y G+ + F C +G+ L G ITC+PG +W P+C + Q
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSR 768
Query: 2077 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETST 2136
G GN ++ + + +G GV++ + +++ + SGS S
Sbjct: 769 QLEG--------GNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGF----SGSHSYSP 816
Query: 2137 V 2137
+
Sbjct: 817 I 817
Score = 182 bits (463), Expect = 4e-45
Identities = 155/571 (27%), Positives = 239/571 (41%), Gaps = 31/571 (5%)
Query: 1201 CGASATNNEGILLSPNYPLNYENNH---ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1257
C + + EG + SP+ +C YSI V G GI I +T +L+Q + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1258 DGKDKTTHLLGAFTGASM--RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1315
G +SM G L S +N+L L F S GF++ Y ++ LS C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 1316 DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECG 1375
P P G +S G T + C+ GY L G L C+ G R +W+ PSC+A CG
Sbjct: 222 FPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1376 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
G + GRI+SP NL C W+IE G + L F + +D L V G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1436 PENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1494
++ + +PE G+ S + ++ ++ + +++F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1495 M-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCIAPCGG 1550
N T PG F C PGY L+ I C+ + W + P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKAMCGG 459
Query: 1551 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1610
L+ +G +LSP++P Y +DC W + V + I L ++ D L ++DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1611 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ESC--FD 1663
++ ++ + + R+ SS + L F++ GF L +K R ++C
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH---- 1719
P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMT 634
Query: 1720 -APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1749
A G + G T +P V + C+
Sbjct: 635 CADPGEIANGHR-TASDAGFPVGSHVQYRCL 664
Score = 171 bits (432), Expect = 2e-41
Identities = 193/787 (24%), Positives = 301/787 (38%), Gaps = 119/787 (15%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSR---DCDWTITVNADYVISLAFISFSIEPNYDFLYI 1604
C N++ G++ SP+ P + DC ++I V Y I + + ++ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1605 YDGPD--------SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1656
G +NS ++G Q + P +N + L F+S GF + Y+A
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSP------TNRLLLHFQSPRVPRGGGFRIHYQAY 216
Query: 1657 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
L SC P +G D G T T++CD+GY LQG TL C+ G RP WN P
Sbjct: 217 LL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 273
Query: 1717 SCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---H 1772
SC A CG + G ++SP +VG N + F + SL +
Sbjct: 274 SCMASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 331
Query: 1773 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
D + V G + S ++ E +S + + S P ++A
Sbjct: 332 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF-- 389
Query: 1833 TSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQ 1887
+C + P G E+ G+ F C PGY L AI C V +
Sbjct: 390 -EEDRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPH 445
Query: 1888 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1947
WND+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 446 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNV 504
Query: 1948 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLE 2003
D L +DG +A L G L S+ +L L FQ+ GF L
Sbjct: 505 REGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH 564
Query: 2004 YTAIGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 2060
+ + D+CPE P G + + G V+++QC+ GY L G +TC W
Sbjct: 565 FKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSW 622
Query: 2061 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2120
+ P C I++ PG + P+G H+Q+ +
Sbjct: 623 SAAPPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYS 668
Query: 2121 IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2180
+ + S +T T K + A +
Sbjct: 669 LEGAAMLTCYSRDTGTP-------------------------------KWSDRVPKCALK 697
Query: 2181 LQSCPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
+ C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 2239 CEA---------LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQ 2289
C+ L GGN+ I P LV + G+G+YI +T LQ
Sbjct: 758 CKVTQTTDPSRQLEGGNLAL---AILLP------------LGLV-IVLGSGVYIYYTKLQ 801
Query: 2290 TEPIYDF 2296
+ ++ F
Sbjct: 802 GKSLFGF 808
Score = 167 bits (422), Expect = 2e-40
Identities = 138/556 (24%), Positives = 231/556 (41%), Gaps = 23/556 (4%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNA---QCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
C +N+ G SP+ C + I V I+I + +L + L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIH-VYPGYGIEIQVQTLNLSQEEELLV 161
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
+ GG G +L + ++ S ++++ LH Q+ GF+++Y+ SC
Sbjct: 162 LAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SC 220
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 682
G P P +G F C G++L GE++++C + W+ P C+ C
Sbjct: 221 GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 683 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
A +G ++SP+ G NL C W I + G R+HL F L+ D L V+ G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 742 SPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 800
SP SP++ +VP L S++ L +E ++ + ++ + F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 801 I-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH 858
N ++ G+ + C G+ ++ G + + W+ P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE 460
Query: 859 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 918
S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 461 LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPS 519
Query: 919 SPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLDPG 974
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 520 ARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPELP 578
Query: 975 IPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG-- 1028
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Query: 1029 GDVRGPSGTILSPGYP 1044
G++ T G+P
Sbjct: 639 GEIANGHRTASDAGFP 654
Score = 122 bits (307), Expect = 5e-27
Identities = 105/424 (24%), Positives = 179/424 (42%), Gaps = 32/424 (7%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P P +G +D G T F CD Y LQG +++ C + +W+ P C +
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-M 276
Query: 506 KTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+CG + + G SP N C WVI A + + ++FE L+ D L
Sbjct: 277 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLM 335
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 620
+ GG P V+ S + D+ ++S + +++ L ++ + + ++ E
Sbjct: 336 VRSGGSPLSP-----VIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 390
Query: 621 KESCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELI---GEKSIVCQENNQ--WSANI 674
++ C P + D + + F C G+ L +I C + + W+
Sbjct: 391 EDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTE 450
Query: 675 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDF 734
P C C + P G VLSPD+P+ Y +C+W + RI L ++ + D
Sbjct: 451 PACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDM 509
Query: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFG 790
L + DGD P + +L G + L S+ L L+FQA + G+GF + +
Sbjct: 510 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 569
Query: 791 HNE-CPDPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 847
N+ CP+ P R + L G+ ++ CE G+ + G++ +TC + WS
Sbjct: 570 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAA 625
Query: 848 IPKC 851
P C
Sbjct: 626 PPAC 629
Score = 89.0 bits (219), Expect = 8e-17
Identities = 62/203 (30%), Positives = 85/203 (41%), Gaps = 12/203 (5%)
Query: 2892 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2951
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 571 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 630
Query: 2952 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 3004
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 631 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 690
Query: 3005 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 3060
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 691 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 749
Query: 3061 SWTGRQPECKAVQCGNPGTTANG 3083
WT + P CK Q +P G
Sbjct: 750 QWTSQPPLCKVTQTTDPSRQLEG 772
Score = 85.9 bits (211), Expect = 7e-16
Identities = 63/195 (32%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 3079 TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIISCGDPG 3137
T ++G + R GT + Y C GY L G + C + +WS P C I++C DPG
Sbjct: 586 TASHGDLIR--GTVLT----YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG 639
Query: 3138 IPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGT----WSGVMPTC--R 3189
ANG R D + VG +V Y C PGY++E G+ + TC T WS +P C +
Sbjct: 640 EIANGHRTASDAGFPVGSHVQYRCLPGYSLE--GAAMLTCYSRDTGTPKWSDRVPKCALK 697
Query: 3190 AVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTWSGEVPQ 3245
C P NG L ++ G S+ + C G+EL +TCV W+ + P
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 3246 CLPKFCGDPGIPAQG 3260
C DP +G
Sbjct: 758 CKVTQTTDPSRQLEG 772
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3192 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3248
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 3249 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3302
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 3303 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3359
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 693 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 751
Query: 3360 SGIQPEC 3366
+ P C
Sbjct: 752 TSQPPLC 758
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2796 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2851
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 594 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 653
Query: 2852 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2905
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 654 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 713
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2950
H + G + + C G+ L G + C P QW P C
Sbjct: 714 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 73.6 bits (179), Expect = 3e-12
Identities = 63/245 (25%), Positives = 97/245 (39%), Gaps = 37/245 (15%)
Query: 2718 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA- 2774
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 2775 GHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHN----WSGQLP 2828
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 2829 SCVPV--SCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2882
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 2883 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--------------GTVVFYDCNPGYF 2928
PP+CKV +DP ++E GN G ++Y G
Sbjct: 753 SQPPLCKVTQTTDP--------SRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKS 804
Query: 2929 LFGSS 2933
LFG S
Sbjct: 805 LFGFS 809
Score = 69.7 bits (169), Expect = 5e-11
Identities = 76/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 25 CGGTLKGLNGTIESP--GFPYGYPNGA-NCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
C + G +ESP G P G +CT+ I I+I Q+ L +E + L L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 82 YDGHPHPTNFRTRLTGFHLPPP--VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
G R L + S + L S GF+++Y+ S CG
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
P P G + T G + C +GY L G L C+ + SW+ P C A
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCMA-- 277
Query: 200 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
+CGGT+ ++ G I SP N C W I A G + L F ++E D L +
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 258 EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDS 291
G P P I+ S M+ P +IS+ L + ++++
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSET 375
Score = 68.2 bits (165), Expect = 1e-10
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 12/259 (4%)
Query: 24 TCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
+CGGT+ G I SP C WVI A E R+ + F+ +L+E+ D L +
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 83 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
G P + + + ++ +S++ + L S+ + + +E + C
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRFEAFEEDRCFA 396
Query: 141 PGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTASWDFPVPICR 196
P + V + G +SC+ GY L+ G P + C+ W+ P C+
Sbjct: 397 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACK 454
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 256
A CGG + +G++ SP +P Y DC W + + I L + E
Sbjct: 455 A--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 512
Query: 257 IEGSEPPTIWLSGMNIPPP 275
+G P L+ + P P
Sbjct: 513 FDGDGPSARVLAQLRGPQP 531
Score = 57.0 bits (136), Expect = 3e-07
Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L G + SP +P Y G +C W + +E RI + + + E D L+L+DG
Sbjct: 457 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 515
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVS----AHGFKVYYEEL-QSSSCG 139
+L G + S+ +L+ + GF ++++E+ ++ +C
Sbjct: 516 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 575
Query: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
P G + D+ G + Y C GY L G LTC + SW P C+
Sbjct: 576 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQK 631
Query: 198 EDACG--GTMRGSSGIISSPSFPNEYHNNADC 227
C G + S FP H C
Sbjct: 632 IMTCADPGEIANGHRTASDAGFPVGSHVQYRC 663
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/136 (32%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 2956 GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 3015
G PG+ P + + G + S T + L QS R + G Q + +
Sbjct: 166 GSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 219
Query: 3016 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKAV 3072
CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA- 277
Query: 3073 QCGNPGTTANGKVFRI 3088
CG GT N + RI
Sbjct: 278 SCG--GTIHNATLGRI 291
Score = 52.8 bits (125), Expect = 6e-06
Identities = 28/63 (44%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C DPGE NG R SD F +GS VQ+ C Y L+GA +TC WSD P C
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 694
Query: 504 KVK 506
+K
Sbjct: 695 ALK 697
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3307 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3365
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 569 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 628
Query: 3366 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3418
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 684
Query: 3419 --WTGKVPIC 3426
W+ +VP C
Sbjct: 685 PKWSDRVPKC 694
Score = 48.5 bits (114), Expect = 1e-04
Identities = 45/187 (24%), Positives = 71/187 (37%), Gaps = 18/187 (9%)
Query: 2529 CSTPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
C+ P +G+ S G + S V++ C G+ L G + C G W VP C
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 694
Query: 2588 --QAISCGIPKAPTNG--GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2643
+ C P P NG + Y G + +FC +G+ L + T V W++
Sbjct: 695 ALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 754
Query: 2644 NKTPRCVVVTCPSIN--------SFILEHGRWRIVNGSHYEYKTKV----VFSCDPGYHG 2691
+ T PS + +L G ++ Y Y TK+ +F G H
Sbjct: 755 PPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFS-GSHS 813
Query: 2692 LGPASIE 2698
P ++E
Sbjct: 814 YSPITVE 820
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
+C +PG G F VG ++Y C+ GY L+G LTC + T W VP
Sbjct: 634 TCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPK 693
Query: 195 C 195
C
Sbjct: 694 C 694
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 133 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 753
Query: 191 PVPICR 196
P+C+
Sbjct: 754 QPPLCK 759
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
Query: 3191 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3247
++C PP+ ++G + T+ G + ++ C GY+L L C+ NGT W+GE P C+
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCM 276
Query: 3248 PKFCG 3252
CG
Sbjct: 277 AS-CG 280
Score = 41.2 bits (95), Expect = 0.019
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2774 AGHCGIPELIVNGQVIGENYG 2794
A G G+++ G
Sbjct: 277 ASCGGTIHNATLGRIVSPEPG 297
Score = 41.2 bits (95), Expect = 0.019
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 619 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 674
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 755
Query: 675 PIC 677
P+C
Sbjct: 756 PLC 758
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3311 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3367
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 219 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 40.4 bits (93), Expect = 0.033
Identities = 39/148 (26%), Positives = 55/148 (37%), Gaps = 27/148 (18%)
Query: 1659 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 699 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 756
Query: 1717 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1776
C V P G N +I +P V+ L V
Sbjct: 757 LC-------------KVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 794
Query: 1777 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1804
+Y Q SL SGSHS + + S
Sbjct: 795 IYYTKLQGKSLF-GFSGSHSYSPITVES 821
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3130 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3186
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 273
Query: 3187 TCRAVTCPTPPQISNGRL 3204
+C A T + GR+
Sbjct: 274 SCMASCGGTIHNATLGRI 291
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2777 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSCVPVS 2834
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 278
Query: 2835 CG 2836
CG
Sbjct: 279 CG 280
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 446 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 701 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 758
Query: 504 KV 505
KV
Sbjct: 759 KV 760
Score = 35.8 bits (81), Expect = 0.80
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2833 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2888
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 35.0 bits (79), Expect = 1.4
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 2949 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 3005
+ ++ CG P P + +S G T + C L G+ + C LNG W+G
Sbjct: 214 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGET 272
Query: 3006 PHCSGDATGT 3015
P C GT
Sbjct: 273 PSCMASCGGT 282
Score = 34.3 bits (77), Expect = 2.3
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3370 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3427
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 276
Query: 3428 A 3428
A
Sbjct: 277 A 277
Score = 33.1 bits (74), Expect = 5.2
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 2683 FSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2720
F CD GY G ++ CL SW E P C + SCG
Sbjct: 244 FHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASCG 280
Score = 32.7 bits (73), Expect = 6.8
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 3573 MSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVHEN 3630
+++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 760 VTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSP 816
Query: 3631 NNGQAAFENPMYD 3643
++ F NP+Y+
Sbjct: 817 ITVESDFSNPLYE 829
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 [Homo
sapiens]
Length = 910
Score = 224 bits (570), Expect = 2e-57
Identities = 181/670 (27%), Positives = 291/670 (43%), Gaps = 36/670 (5%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSL---DCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2127
C +S+ G + SP +L DCT++I++ G+G+ +Q + + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 2128 RSGSSE--TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2185
G S ++ S L S T+ L+F S GF I YQAY L
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGF 292
Query: 2186 DPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGG 2245
PRP +G V D G T +F C GY L G L CL+G +WN P C A CGG
Sbjct: 293 PPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGG 351
Query: 2246 NI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPD 2304
I A G I SP C W++ G ++++F + + D + V G
Sbjct: 352 TIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGS 411
Query: 2305 QNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRVCQPPPPVP 2362
SP I + E + S + + ++ S+ + + L + A++ C P +
Sbjct: 412 PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF-LA 470
Query: 2363 NAEILTEDDEFEIGDIIRYQCLPGFTLVG----NAILTCRLGERLQMDGAPPVCQVLCPA 2418
+ + T D E+ G + + CLPG+ L NAI C + P C+ +C
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEPACKAMC-G 528
Query: 2419 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2478
EL + GV+LSP +P SY Q C W + V++ I + VE +E D+L ++DG
Sbjct: 529 GELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGDMLTLFDGD 586
Query: 2479 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPES---- 2534
+ VL L G + S+G ++ LQ+ A G G ++ + P +
Sbjct: 587 GPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 645
Query: 2535 ---PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2589
PP + + G L +V+ + C+ G+ L+G C+ +W A PACQ
Sbjct: 646 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWSAAPPACQK 701
Query: 2590 I-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2646
I +C P NG +D + VG+ V Y C GY L + T + GT ++
Sbjct: 702 IMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV 761
Query: 2647 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2706
P+C + P +N + E+G ++ + HY+ + F C G+ +G +I C+P
Sbjct: 762 PKCALKYEPCLNPGVPENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ 820
Query: 2707 WRNERPYCQI 2716
W ++ P C++
Sbjct: 821 WTSQPPLCKV 830
Score = 212 bits (540), Expect = 5e-54
Identities = 194/740 (26%), Positives = 292/740 (39%), Gaps = 79/740 (10%)
Query: 1894 TCIVPCGGILTKRKGTILSPGYPEPYDNNL---NCVWKITVPEGAGIQVQVVSFATEHNW 1950
T V C +++ +G + SP P L +C + I V G GI++QV +
Sbjct: 168 TSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEE 227
Query: 1951 DSLDFYDGGDNN-APRLGSYSGTTIP-HLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIG 2008
+ L GG APRL + S +L S +N L L+FQS GF + Y A
Sbjct: 228 ELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYL 287
Query: 2009 LDSCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2067
L SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C
Sbjct: 288 L-SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Query: 2068 LAQCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE 2126
+A CGG + + + G I+SP G +L C W I G +HL F S + +D L
Sbjct: 346 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 405
Query: 2127 VRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2185
VRSG S S VI +P L S + S+ N + ++A++ C
Sbjct: 406 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 465
Query: 2186 DPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCE 2240
P +G V D + G +F C PGY L +A+ C+ +WN P C+
Sbjct: 466 APF-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 524
Query: 2241 ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2300
A+CGG ++ G + SP +P Y QDC W V V I + +L D +T++
Sbjct: 525 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLF 583
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRV 2354
DG ++ + Q G + S+ + ++F + GF + +
Sbjct: 584 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 643
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
C PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ- 700
Query: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
+ CA + G+ ++ F V
Sbjct: 701 -------------------------KIMTCADPGEIANGHRTA-------SDAGFPV--- 725
Query: 2475 YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CST 2531
G ++Q Y + G + +S D G K R+ A C
Sbjct: 726 --GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLN 773
Query: 2532 PESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2590
P P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 774 PGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCKVT 831
Query: 2591 SCGIPKAPTNGGILTTDYLV 2610
P GG L L+
Sbjct: 832 QTTDPSRQLEGGNLALAILL 851
Score = 207 bits (528), Expect = 1e-52
Identities = 186/714 (26%), Positives = 298/714 (41%), Gaps = 82/714 (11%)
Query: 855 CGGHFSAPSGVILSPGWPGYYKDSL---NCEWVIEAEPGHSIKITFERFQTELNYDVLEV 911
C + S G + SP +L +C + I PG+ I+I + ++L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 912 HDG--PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYS 969
G P L LL + + Q L S +N + L F + GF+IHY++ + S
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL---S 289
Query: 970 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDALC 1027
C P P HG D G T +F CDSGY+L EE L+C W+ P+C A C
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 349
Query: 1028 GGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1086
GG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 350 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 409
Query: 1087 GSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCEDP 1145
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C P
Sbjct: 410 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 467
Query: 1146 GIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAEC 1201
+ + + G TFSC GY LE + I C+ W+ P C A C
Sbjct: 468 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 527
Query: 1202 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1261
G + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 528 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 587
Query: 1262 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CED 1316
+ +L G R LSS L L+F + G +GF L + + C +
Sbjct: 588 PSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 646
Query: 1317 PGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAE 1373
P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 647 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMT 704
Query: 1374 CGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVW 1432
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 705 CADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT---- 752
Query: 1433 DGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPG 1492
P +D + K A+++ C +PG
Sbjct: 753 GTPKWSDRVPK--------------------------------CALKYE-----PCLNPG 775
Query: 1493 VPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
VP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 776 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 828
Score = 206 bits (524), Expect = 3e-52
Identities = 190/781 (24%), Positives = 318/781 (40%), Gaps = 96/781 (12%)
Query: 1381 ESSGRILSPGYPFPYDNNLR---CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1437
E G + SP P L C + I V PG + +Q + ++L + G
Sbjct: 179 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 238
Query: 1438 NDMLLKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
+ S++ EG + S N + + F + GF I + + + + C P P
Sbjct: 239 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPA 297
Query: 1496 NGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGS 1555
+G + PG T F CD GY+LQGEE + C+ R W P C+A CGG + +
Sbjct: 298 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 356
Query: 1556 S-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPL 1614
+ G I+SP + C W I + L F S++ + D L + G SP+
Sbjct: 357 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 416
Query: 1615 IGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP----GNIMN 1669
I +PER + S + ++++ S+ + L ++A + CF P GN+
Sbjct: 417 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV-- 474
Query: 1670 GTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGWNRALPSCHAPCGSRS 1726
T +Y+ G+ T+ C GY L+ + + C+ D P WN P+C A CG
Sbjct: 475 -TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACKAMCGGEL 531
Query: 1727 TGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS 1786
+ G VLSP++P++YS G +CV+ + V +E + Q D++ ++DG +
Sbjct: 532 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSAR 591
Query: 1787 LLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVYQAVPRTSSTQCSSVP 1842
+L+ L G L LSSG +T++F + P +GF ++ VPR + C +P
Sbjct: 592 VLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELP 648
Query: 1843 EPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1900
P +G R + + G+ + + C PGY L GS + C QW+ S C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--------QWDLSWSAAPPACQ 700
Query: 1901 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSLDFYDGG 1959
I+T ++ G+ D P G+ +Q + + ++ E
Sbjct: 701 KIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGYSLE------------ 740
Query: 1960 DNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPS 2019
A L YS D + A+ + C P P
Sbjct: 741 --GAAMLTCYS--------------------RDTGTPKWSDRVPKCALKYEPCLNPGVPE 778
Query: 2020 SGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMS 2076
+G + Y G+ + F C +G+ L G ITC+PG +W P+C + Q
Sbjct: 779 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSR 838
Query: 2077 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETST 2136
G GN ++ + + +G GV++ + +++ + SGS S
Sbjct: 839 QLEG--------GNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGF----SGSHSYSP 886
Query: 2137 V 2137
+
Sbjct: 887 I 887
Score = 182 bits (463), Expect = 4e-45
Identities = 155/571 (27%), Positives = 239/571 (41%), Gaps = 31/571 (5%)
Query: 1201 CGASATNNEGILLSPNYPLNYENNH---ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1257
C + + EG + SP+ +C YSI V G GI I +T +L+Q + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1258 DGKDKTTHLLGAFTGASM--RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1315
G +SM G L S +N+L L F S GF++ Y ++ LS C
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 291
Query: 1316 DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECG 1375
P P G +S G T + C+ GY L G L C+ G R +W+ PSC+A CG
Sbjct: 292 FPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 350
Query: 1376 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
G + GRI+SP NL C W+IE G + L F + +D L V G
Sbjct: 351 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 410
Query: 1436 PENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1494
++ + +PE G+ S + ++ ++ + +++F + C P +
Sbjct: 411 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 470
Query: 1495 M-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCIAPCGG 1550
N T PG F C PGY L+ I C+ + W + P C A CGG
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKAMCGG 529
Query: 1551 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1610
L+ +G +LSP++P Y +DC W + V + I L ++ D L ++DG
Sbjct: 530 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 588
Query: 1611 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ESC--FD 1663
++ ++ + + R+ SS + L F++ GF L +K R ++C
Sbjct: 589 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 648
Query: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH---- 1719
P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMT 704
Query: 1720 -APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1749
A G + G T +P V + C+
Sbjct: 705 CADPGEIANGHR-TASDAGFPVGSHVQYRCL 734
Score = 171 bits (432), Expect = 2e-41
Identities = 193/787 (24%), Positives = 301/787 (38%), Gaps = 119/787 (15%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSR---DCDWTITVNADYVISLAFISFSIEPNYDFLYI 1604
C N++ G++ SP+ P + DC ++I V Y I + + ++ + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1605 YDGPD--------SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1656
G +NS ++G Q + P +N + L F+S GF + Y+A
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSP------TNRLLLHFQSPRVPRGGGFRIHYQAY 286
Query: 1657 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
L SC P +G D G T T++CD+GY LQG TL C+ G RP WN P
Sbjct: 287 LL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 343
Query: 1717 SCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---H 1772
SC A CG + G ++SP +VG N + F + SL +
Sbjct: 344 SCMASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 401
Query: 1773 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
D + V G + S ++ E +S + + S P ++A
Sbjct: 402 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF-- 459
Query: 1833 TSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQ 1887
+C + P G E+ G+ F C PGY L AI C V +
Sbjct: 460 -EEDRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPH 515
Query: 1888 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1947
WND+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 516 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNV 574
Query: 1948 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLE 2003
D L +DG +A L G L S+ +L L FQ+ GF L
Sbjct: 575 REGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH 634
Query: 2004 YTAIGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 2060
+ + D+CPE P G + + G V+++QC+ GY L G +TC W
Sbjct: 635 FKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSW 692
Query: 2061 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2120
+ P C I++ PG + P+G H+Q+ +
Sbjct: 693 SAAPPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYS 738
Query: 2121 IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2180
+ + S +T T K + A +
Sbjct: 739 LEGAAMLTCYSRDTGTP-------------------------------KWSDRVPKCALK 767
Query: 2181 LQSCPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
+ C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P
Sbjct: 768 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 827
Query: 2239 CEA---------LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQ 2289
C+ L GGN+ I P LV + G+G+YI +T LQ
Sbjct: 828 CKVTQTTDPSRQLEGGNLAL---AILLP------------LGLV-IVLGSGVYIYYTKLQ 871
Query: 2290 TEPIYDF 2296
+ ++ F
Sbjct: 872 GKSLFGF 878
Score = 167 bits (422), Expect = 2e-40
Identities = 138/556 (24%), Positives = 231/556 (41%), Gaps = 23/556 (4%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNA---QCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
C +N+ G SP+ C + I V I+I + +L + L
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIH-VYPGYGIEIQVQTLNLSQEEELLV 231
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
+ GG G +L + ++ S ++++ LH Q+ GF+++Y+ SC
Sbjct: 232 LAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SC 290
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 682
G P P +G F C G++L GE++++C + W+ P C+ C
Sbjct: 291 GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 350
Query: 683 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
A +G ++SP+ G NL C W I + G R+HL F L+ D L V+ G
Sbjct: 351 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 410
Query: 742 SPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 800
SP SP++ +VP L S++ L +E ++ + ++ + F + C P +
Sbjct: 411 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 470
Query: 801 I-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH 858
N ++ G+ + C G+ ++ G + + W+ P C A CGG
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE 530
Query: 859 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 918
S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 531 LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPS 589
Query: 919 SPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLDPG 974
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 590 ARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPELP 648
Query: 975 IPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG-- 1028
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 708
Query: 1029 GDVRGPSGTILSPGYP 1044
G++ T G+P
Sbjct: 709 GEIANGHRTASDAGFP 724
Score = 122 bits (307), Expect = 5e-27
Identities = 105/424 (24%), Positives = 179/424 (42%), Gaps = 32/424 (7%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P P +G +D G T F CD Y LQG +++ C + +W+ P C +
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-M 346
Query: 506 KTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+CG + + G SP N C WVI A + + ++FE L+ D L
Sbjct: 347 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLM 405
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 620
+ GG P V+ S + D+ ++S + +++ L ++ + + ++ E
Sbjct: 406 VRSGGSPLSP-----VIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 460
Query: 621 KESCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELI---GEKSIVCQENNQ--WSANI 674
++ C P + D + + F C G+ L +I C + + W+
Sbjct: 461 EDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTE 520
Query: 675 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDF 734
P C C + P G VLSPD+P+ Y +C+W + RI L ++ + D
Sbjct: 521 PACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDM 579
Query: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFG 790
L + DGD P + +L G + L S+ L L+FQA + G+GF + +
Sbjct: 580 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 639
Query: 791 HNE-CPDPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 847
N+ CP+ P R + L G+ ++ CE G+ + G++ +TC + WS
Sbjct: 640 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAA 695
Query: 848 IPKC 851
P C
Sbjct: 696 PPAC 699
Score = 89.0 bits (219), Expect = 8e-17
Identities = 62/203 (30%), Positives = 85/203 (41%), Gaps = 12/203 (5%)
Query: 2892 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2951
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 641 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 700
Query: 2952 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 3004
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 701 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 760
Query: 3005 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 3060
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 761 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 819
Query: 3061 SWTGRQPECKAVQCGNPGTTANG 3083
WT + P CK Q +P G
Sbjct: 820 QWTSQPPLCKVTQTTDPSRQLEG 842
Score = 85.9 bits (211), Expect = 7e-16
Identities = 63/195 (32%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 3079 TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIISCGDPG 3137
T ++G + R GT + Y C GY L G + C + +WS P C I++C DPG
Sbjct: 656 TASHGDLIR--GTVLT----YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG 709
Query: 3138 IPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGT----WSGVMPTC--R 3189
ANG R D + VG +V Y C PGY++E G+ + TC T WS +P C +
Sbjct: 710 EIANGHRTASDAGFPVGSHVQYRCLPGYSLE--GAAMLTCYSRDTGTPKWSDRVPKCALK 767
Query: 3190 AVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTWSGEVPQ 3245
C P NG L ++ G S+ + C G+EL +TCV W+ + P
Sbjct: 768 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 827
Query: 3246 CLPKFCGDPGIPAQG 3260
C DP +G
Sbjct: 828 CKVTQTTDPSRQLEG 842
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3192 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3248
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 643 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 3249 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3302
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 3303 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3359
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 763 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 821
Query: 3360 SGIQPEC 3366
+ P C
Sbjct: 822 TSQPPLC 828
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2796 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2851
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 664 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 723
Query: 2852 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2905
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 724 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 783
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2950
H + G + + C G+ L G + C P QW P C
Sbjct: 784 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 828
Score = 73.6 bits (179), Expect = 3e-12
Identities = 63/245 (25%), Positives = 97/245 (39%), Gaps = 37/245 (15%)
Query: 2718 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA- 2774
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 643 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 2775 GHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHN----WSGQLP 2828
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 2829 SCVPV--SCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2882
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 763 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 822
Query: 2883 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--------------GTVVFYDCNPGYF 2928
PP+CKV +DP ++E GN G ++Y G
Sbjct: 823 SQPPLCKVTQTTDP--------SRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKS 874
Query: 2929 LFGSS 2933
LFG S
Sbjct: 875 LFGFS 879
Score = 69.7 bits (169), Expect = 5e-11
Identities = 76/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 25 CGGTLKGLNGTIESP--GFPYGYPNGA-NCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
C + G +ESP G P G +CT+ I I+I Q+ L +E + L L
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 82 YDGHPHPTNFRTRLTGFHLPPP--VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
G R L + S + L S GF+++Y+ S CG
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 291
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
P P G + T G + C +GY L G L C+ + SW+ P C A
Sbjct: 292 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCMA-- 347
Query: 200 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
+CGGT+ ++ G I SP N C W I A G + L F ++E D L +
Sbjct: 348 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 407
Query: 258 EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDS 291
G P P I+ S M+ P +IS+ L + ++++
Sbjct: 408 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSET 445
Score = 68.2 bits (165), Expect = 1e-10
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 12/259 (4%)
Query: 24 TCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
+CGGT+ G I SP C WVI A E R+ + F+ +L+E+ D L +
Sbjct: 348 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 407
Query: 83 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
G P + + + ++ +S++ + L S+ + + +E + C
Sbjct: 408 SGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRFEAFEEDRCFA 466
Query: 141 PGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTASWDFPVPICR 196
P + V + G +SC+ GY L+ G P + C+ W+ P C+
Sbjct: 467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACK 524
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 256
A CGG + +G++ SP +P Y DC W + + I L + E
Sbjct: 525 A--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 582
Query: 257 IEGSEPPTIWLSGMNIPPP 275
+G P L+ + P P
Sbjct: 583 FDGDGPSARVLAQLRGPQP 601
Score = 57.0 bits (136), Expect = 3e-07
Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L G + SP +P Y G +C W + +E RI + + + E D L+L+DG
Sbjct: 527 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 585
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVS----AHGFKVYYEEL-QSSSCG 139
+L G + S+ +L+ + GF ++++E+ ++ +C
Sbjct: 586 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 645
Query: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
P G + D+ G + Y C GY L G LTC + SW P C+
Sbjct: 646 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQK 701
Query: 198 EDACG--GTMRGSSGIISSPSFPNEYHNNADC 227
C G + S FP H C
Sbjct: 702 IMTCADPGEIANGHRTASDAGFPVGSHVQYRC 733
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/136 (32%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 2956 GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 3015
G PG+ P + + G + S T + L QS R + G Q + +
Sbjct: 236 GSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 289
Query: 3016 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKAV 3072
CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA- 347
Query: 3073 QCGNPGTTANGKVFRI 3088
CG GT N + RI
Sbjct: 348 SCG--GTIHNATLGRI 361
Score = 52.8 bits (125), Expect = 6e-06
Identities = 28/63 (44%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C DPGE NG R SD F +GS VQ+ C Y L+GA +TC WSD P C
Sbjct: 705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 764
Query: 504 KVK 506
+K
Sbjct: 765 ALK 767
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3307 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3365
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 639 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 698
Query: 3366 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3418
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 699 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 754
Query: 3419 --WTGKVPIC 3426
W+ +VP C
Sbjct: 755 PKWSDRVPKC 764
Score = 48.5 bits (114), Expect = 1e-04
Identities = 45/187 (24%), Positives = 71/187 (37%), Gaps = 18/187 (9%)
Query: 2529 CSTPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
C+ P +G+ S G + S V++ C G+ L G + C G W VP C
Sbjct: 705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 764
Query: 2588 --QAISCGIPKAPTNG--GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2643
+ C P P NG + Y G + +FC +G+ L + T V W++
Sbjct: 765 ALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 824
Query: 2644 NKTPRCVVVTCPSIN--------SFILEHGRWRIVNGSHYEYKTKV----VFSCDPGYHG 2691
+ T PS + +L G ++ Y Y TK+ +F G H
Sbjct: 825 PPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFS-GSHS 883
Query: 2692 LGPASIE 2698
P ++E
Sbjct: 884 YSPITVE 890
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
+C +PG G F VG ++Y C+ GY L+G LTC + T W VP
Sbjct: 704 TCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPK 763
Query: 195 C 195
C
Sbjct: 764 C 764
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 133 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 766 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 823
Query: 191 PVPICR 196
P+C+
Sbjct: 824 QPPLCK 829
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
Query: 3191 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3247
++C PP+ ++G + T+ G + ++ C GY+L L C+ NGT W+GE P C+
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCM 346
Query: 3248 PKFCG 3252
CG
Sbjct: 347 AS-CG 350
Score = 41.2 bits (95), Expect = 0.019
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Query: 2774 AGHCGIPELIVNGQVIGENYG 2794
A G G+++ G
Sbjct: 347 ASCGGTIHNATLGRIVSPEPG 367
Score = 41.2 bits (95), Expect = 0.019
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 619 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 674
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 766 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 825
Query: 675 PIC 677
P+C
Sbjct: 826 PLC 828
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3311 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3367
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 289 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Score = 40.4 bits (93), Expect = 0.033
Identities = 39/148 (26%), Positives = 55/148 (37%), Gaps = 27/148 (18%)
Query: 1659 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 769 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 826
Query: 1717 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1776
C V P G N +I +P V+ L V
Sbjct: 827 LC-------------KVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 864
Query: 1777 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1804
+Y Q SL SGSHS + + S
Sbjct: 865 IYYTKLQGKSLF-GFSGSHSYSPITVES 891
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3130 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3186
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 343
Query: 3187 TCRAVTCPTPPQISNGRL 3204
+C A T + GR+
Sbjct: 344 SCMASCGGTIHNATLGRI 361
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2777 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSCVPVS 2834
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 348
Query: 2835 CG 2836
CG
Sbjct: 349 CG 350
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 446 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 771 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 828
Query: 504 KV 505
KV
Sbjct: 829 KV 830
Score = 35.8 bits (81), Expect = 0.80
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2833 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2888
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Score = 35.0 bits (79), Expect = 1.4
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 2949 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 3005
+ ++ CG P P + +S G T + C L G+ + C LNG W+G
Sbjct: 284 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGET 342
Query: 3006 PHCSGDATGT 3015
P C GT
Sbjct: 343 PSCMASCGGT 352
Score = 34.3 bits (77), Expect = 2.3
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3370 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3427
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 289 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 346
Query: 3428 A 3428
A
Sbjct: 347 A 347
Score = 33.1 bits (74), Expect = 5.2
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 2683 FSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2720
F CD GY G ++ CL SW E P C + SCG
Sbjct: 314 FHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASCG 350
Score = 32.7 bits (73), Expect = 6.8
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 3573 MSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVHEN 3630
+++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 830 VTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSP 886
Query: 3631 NNGQAAFENPMYD 3643
++ F NP+Y+
Sbjct: 887 ITVESDFSNPLYE 899
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 224 bits (570), Expect = 2e-57
Identities = 181/670 (27%), Positives = 291/670 (43%), Gaps = 36/670 (5%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSL---DCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2127
C +S+ G + SP +L DCT++I++ G+G+ +Q + + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2128 RSGSSE--TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2185
G S ++ S L S T+ L+F S GF I YQAY L
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGF 222
Query: 2186 DPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGG 2245
PRP +G V D G T +F C GY L G L CL+G +WN P C A CGG
Sbjct: 223 PPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGG 281
Query: 2246 NI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPD 2304
I A G I SP C W++ G ++++F + + D + V G
Sbjct: 282 TIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGS 341
Query: 2305 QNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRVCQPPPPVP 2362
SP I + E + S + + ++ S+ + + L + A++ C P +
Sbjct: 342 PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF-LA 400
Query: 2363 NAEILTEDDEFEIGDIIRYQCLPGFTLVG----NAILTCRLGERLQMDGAPPVCQVLCPA 2418
+ + T D E+ G + + CLPG+ L NAI C + P C+ +C
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEPACKAMC-G 458
Query: 2419 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2478
EL + GV+LSP +P SY Q C W + V++ I + VE +E D+L ++DG
Sbjct: 459 GELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGDMLTLFDGD 516
Query: 2479 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPES---- 2534
+ VL L G + S+G ++ LQ+ A G G ++ + P +
Sbjct: 517 GPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 575
Query: 2535 ---PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2589
PP + + G L +V+ + C+ G+ L+G C+ +W A PACQ
Sbjct: 576 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWSAAPPACQK 631
Query: 2590 I-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2646
I +C P NG +D + VG+ V Y C GY L + T + GT ++
Sbjct: 632 IMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV 691
Query: 2647 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2706
P+C + P +N + E+G ++ + HY+ + F C G+ +G +I C+P
Sbjct: 692 PKCALKYEPCLNPGVPENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ 750
Query: 2707 WRNERPYCQI 2716
W ++ P C++
Sbjct: 751 WTSQPPLCKV 760
Score = 208 bits (529), Expect = 9e-53
Identities = 189/718 (26%), Positives = 286/718 (39%), Gaps = 79/718 (11%)
Query: 1894 TCIVPCGGILTKRKGTILSPGYPEPYDNNL---NCVWKITVPEGAGIQVQVVSFATEHNW 1950
T V C +++ +G + SP P L +C + I V G GI++QV +
Sbjct: 98 TSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEE 157
Query: 1951 DSLDFYDGGDNN-APRLGSYSGTTIP-HLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIG 2008
+ L GG APRL + S +L S +N L L+FQS GF + Y A
Sbjct: 158 ELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYL 217
Query: 2009 LDSCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2067
L SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C
Sbjct: 218 L-SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 2068 LAQCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE 2126
+A CGG + + + G I+SP G +L C W I G +HL F S + +D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 2127 VRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2185
VRSG S S VI +P L S + S+ N + ++A++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 2186 DPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCE 2240
P +G V D + G +F C PGY L +A+ C+ +WN P C+
Sbjct: 396 APF-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 454
Query: 2241 ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2300
A+CGG ++ G + SP +P Y QDC W V V I + +L D +T++
Sbjct: 455 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLF 513
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRV 2354
DG ++ + Q G + S+ + ++F + GF + +
Sbjct: 514 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 573
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
C PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ- 630
Query: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
+ CA + G+ ++ F V
Sbjct: 631 -------------------------KIMTCADPGEIANGHRTA-------SDAGFPV--- 655
Query: 2475 YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CST 2531
G ++Q Y + G + +S D G K R+ A C
Sbjct: 656 --GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLN 703
Query: 2532 PESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
P P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 704 PGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCK 759
Score = 207 bits (528), Expect = 1e-52
Identities = 186/714 (26%), Positives = 298/714 (41%), Gaps = 82/714 (11%)
Query: 855 CGGHFSAPSGVILSPGWPGYYKDSL---NCEWVIEAEPGHSIKITFERFQTELNYDVLEV 911
C + S G + SP +L +C + I PG+ I+I + ++L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 912 HDG--PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYS 969
G P L LL + + Q L S +N + L F + GF+IHY++ + S
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL---S 219
Query: 970 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDALC 1027
C P P HG D G T +F CDSGY+L EE L+C W+ P+C A C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 279
Query: 1028 GGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1086
GG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 1087 GSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCEDP 1145
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C P
Sbjct: 340 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 397
Query: 1146 GIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAEC 1201
+ + + G TFSC GY LE + I C+ W+ P C A C
Sbjct: 398 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 457
Query: 1202 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1261
G + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 458 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 517
Query: 1262 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CED 1316
+ +L G R LSS L L+F + G +GF L + + C +
Sbjct: 518 PSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 576
Query: 1317 PGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAE 1373
P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 577 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMT 634
Query: 1374 CGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVW 1432
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT---- 682
Query: 1433 DGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPG 1492
P +D + K A+++ C +PG
Sbjct: 683 GTPKWSDRVPK--------------------------------CALKYE-----PCLNPG 705
Query: 1493 VPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
VP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 706 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 758
Score = 206 bits (524), Expect = 3e-52
Identities = 190/786 (24%), Positives = 317/786 (40%), Gaps = 93/786 (11%)
Query: 1381 ESSGRILSPGYPFPYDNNLR---CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1437
E G + SP P L C + I V PG + +Q + ++L + G
Sbjct: 109 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 168
Query: 1438 NDMLLKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
+ S++ EG + S N + + F + GF I + + + + C P P
Sbjct: 169 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPA 227
Query: 1496 NGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGS 1555
+G + PG T F CD GY+LQGEE + C+ R W P C+A CGG + +
Sbjct: 228 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 286
Query: 1556 S-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPL 1614
+ G I+SP + C W I + L F S++ + D L + G SP+
Sbjct: 287 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 346
Query: 1615 IGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP----GNIMN 1669
I +PER + S + ++++ S+ + L ++A + CF P GN+
Sbjct: 347 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV-- 404
Query: 1670 GTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGWNRALPSCHAPCGSRS 1726
T +Y+ G+ T+ C GY L+ + + C+ D P WN P+C A CG
Sbjct: 405 -TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACKAMCGGEL 461
Query: 1727 TGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS 1786
+ G VLSP++P++YS G +CV+ + V +E + Q D++ ++DG +
Sbjct: 462 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSAR 521
Query: 1787 LLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVYQAVPRTSSTQCSSVP 1842
+L+ L G L LSSG +T++F + P +GF ++ VPR + C +P
Sbjct: 522 VLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELP 578
Query: 1843 EPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1900
P +G R + + G+ + + C PGY L GS + C QW+ S C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--------QWDLSWSAAPPACQ 630
Query: 1901 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSLDFYDGG 1959
I+T ++ G+ D P G+ +Q + + ++ E
Sbjct: 631 KIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGYSLE------------ 670
Query: 1960 DNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPS 2019
A L YS D + A+ + C P P
Sbjct: 671 --GAAMLTCYS--------------------RDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 2020 SGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSD 2077
+G + Y G+ + F C +G+ L G ITC+PG +W P+C + +
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDN 768
Query: 2078 FSGVILSPGFPGNYPSSLDCTWTINLPIGF------GVHLQFVNFSTETIHDYLEVRSGS 2131
+ P + I LP+G GV++ + +++ + SGS
Sbjct: 769 RKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGF----SGS 824
Query: 2132 SETSTV 2137
S +
Sbjct: 825 HSYSPI 830
Score = 182 bits (463), Expect = 4e-45
Identities = 155/571 (27%), Positives = 239/571 (41%), Gaps = 31/571 (5%)
Query: 1201 CGASATNNEGILLSPNYPLNYENNH---ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1257
C + + EG + SP+ +C YSI V G GI I +T +L+Q + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1258 DGKDKTTHLLGAFTGASM--RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1315
G +SM G L S +N+L L F S GF++ Y ++ LS C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 1316 DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECG 1375
P P G +S G T + C+ GY L G L C+ G R +W+ PSC+A CG
Sbjct: 222 FPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1376 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
G + GRI+SP NL C W+IE G + L F + +D L V G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1436 PENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1494
++ + +PE G+ S + ++ ++ + +++F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1495 M-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCIAPCGG 1550
N T PG F C PGY L+ I C+ + W + P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKAMCGG 459
Query: 1551 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1610
L+ +G +LSP++P Y +DC W + V + I L ++ D L ++DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1611 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ESC--FD 1663
++ ++ + + R+ SS + L F++ GF L +K R ++C
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH---- 1719
P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMT 634
Query: 1720 -APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1749
A G + G T +P V + C+
Sbjct: 635 CADPGEIANGHR-TASDAGFPVGSHVQYRCL 664
Score = 170 bits (431), Expect = 2e-41
Identities = 192/786 (24%), Positives = 300/786 (38%), Gaps = 104/786 (13%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSR---DCDWTITVNADYVISLAFISFSIEPNYDFLYI 1604
C N++ G++ SP+ P + DC ++I V Y I + + ++ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1605 YDGPD--------SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1656
G +NS ++G Q + P +N + L F+S GF + Y+A
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSP------TNRLLLHFQSPRVPRGGGFRIHYQAY 216
Query: 1657 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
L SC P +G D G T T++CD+GY LQG TL C+ G RP WN P
Sbjct: 217 LL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 273
Query: 1717 SCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---H 1772
SC A CG + G ++SP +VG N + F + SL +
Sbjct: 274 SCMASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 331
Query: 1773 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
D + V G + S ++ E +S + + S P ++A
Sbjct: 332 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF-- 389
Query: 1833 TSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQ 1887
+C + P G E+ G+ F C PGY L AI C V +
Sbjct: 390 -EEDRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPH 445
Query: 1888 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1947
WND+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 446 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNV 504
Query: 1948 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLE 2003
D L +DG +A L G L S+ +L L FQ+ GF L
Sbjct: 505 REGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH 564
Query: 2004 YTAIGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 2060
+ + D+CPE P G + + G V+++QC+ GY L G +TC W
Sbjct: 565 FKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSW 622
Query: 2061 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2120
+ P C I++ PG + P+G H+Q+ +
Sbjct: 623 SAAPPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYS 668
Query: 2121 IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2180
+ + S +T T K + A +
Sbjct: 669 LEGAAMLTCYSRDTGTP-------------------------------KWSDRVPKCALK 697
Query: 2181 LQSCPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
+ C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 2239 C-----EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWL---VRVPPGNGIYINFTVLQT 2290
C E L + T P E N L + + G+G+YI +T LQ
Sbjct: 758 CKVAYEELLDNRKLEVTQTT--DPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQG 815
Query: 2291 EPIYDF 2296
+ ++ F
Sbjct: 816 KSLFGF 821
Score = 167 bits (422), Expect = 2e-40
Identities = 138/556 (24%), Positives = 231/556 (41%), Gaps = 23/556 (4%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNA---QCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
C +N+ G SP+ C + I V I+I + +L + L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIH-VYPGYGIEIQVQTLNLSQEEELLV 161
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
+ GG G +L + ++ S ++++ LH Q+ GF+++Y+ SC
Sbjct: 162 LAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SC 220
Query: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 682
G P P +G F C G++L GE++++C + W+ P C+ C
Sbjct: 221 GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 683 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
A +G ++SP+ G NL C W I + G R+HL F L+ D L V+ G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 742 SPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 800
SP SP++ +VP L S++ L +E ++ + ++ + F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 801 I-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH 858
N ++ G+ + C G+ ++ G + + W+ P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE 460
Query: 859 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 918
S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 461 LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPS 519
Query: 919 SPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLDPG 974
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 520 ARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPELP 578
Query: 975 IPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG-- 1028
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Query: 1029 GDVRGPSGTILSPGYP 1044
G++ T G+P
Sbjct: 639 GEIANGHRTASDAGFP 654
Score = 122 bits (307), Expect = 5e-27
Identities = 105/424 (24%), Positives = 179/424 (42%), Gaps = 32/424 (7%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P P +G +D G T F CD Y LQG +++ C + +W+ P C +
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-M 276
Query: 506 KTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+CG + + G SP N C WVI A + + ++FE L+ D L
Sbjct: 277 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLM 335
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 620
+ GG P V+ S + D+ ++S + +++ L ++ + + ++ E
Sbjct: 336 VRSGGSPLSP-----VIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 390
Query: 621 KESCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELI---GEKSIVCQENNQ--WSANI 674
++ C P + D + + F C G+ L +I C + + W+
Sbjct: 391 EDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTE 450
Query: 675 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDF 734
P C C + P G VLSPD+P+ Y +C+W + RI L ++ + D
Sbjct: 451 PACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDM 509
Query: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFG 790
L + DGD P + +L G + L S+ L L+FQA + G+GF + +
Sbjct: 510 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 569
Query: 791 HNE-CPDPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 847
N+ CP+ P R + L G+ ++ CE G+ + G++ +TC + WS
Sbjct: 570 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAA 625
Query: 848 IPKC 851
P C
Sbjct: 626 PPAC 629
Score = 94.7 bits (234), Expect = 1e-18
Identities = 60/170 (35%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 3148 DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV-TCPTPPQISNGRLEG 3206
D + G ++Y C+PGY EL GS I TC + +WS P C+ + TC P +I+NG
Sbjct: 591 DLIRGTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA 648
Query: 3207 TN--FDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKF--CGDPGIPA 3258
++ F G + Y C PGY L A+LTC G WS VP+C K+ C +PG+P
Sbjct: 649 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 3259 QGKREGKSFIYQS--EVSFSCNFPFILVGSSTRICQA--DGTWSGSSPHC 3304
G + YQ+ + F C F L+G T C W+ P C
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 88.2 bits (217), Expect = 1e-16
Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 16/189 (8%)
Query: 3015 TCGDPGTPGHGSRQESN--FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC-KA 3071
TC + P G R S+ + + Y C+ GY L GS+ TC + SW+ P C K
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 3072 VQCGNPGTTANGKVFRID-GTTFSSSVIYSCMEGYILSGPSVRQCTANGT----WSGTLP 3126
+ C +PG ANG D G S V Y C+ GY L G ++ C + T WS +P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 3127 NCTI--ISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN--GT 3180
C + C +PG+P NG + Y Y G+++ + C G+ EL G TC
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGF--ELIGEVTITCVPGHPSQ 750
Query: 3181 WSGVMPTCR 3189
W+ P C+
Sbjct: 751 WTSQPPLCK 759
Score = 84.0 bits (206), Expect = 3e-15
Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 2892 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2951
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 571 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 630
Query: 2952 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 3004
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 631 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 690
Query: 3005 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 3060
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 691 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 749
Query: 3061 SWTGRQPECK 3070
WT + P CK
Sbjct: 750 QWTSQPPLCK 759
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3192 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3248
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 3249 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3302
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 3303 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3359
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 693 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 751
Query: 3360 SGIQPEC 3366
+ P C
Sbjct: 752 TSQPPLC 758
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2796 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2851
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 594 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 653
Query: 2852 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2905
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 654 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 713
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2950
H + G + + C G+ L G + C P QW P C
Sbjct: 714 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 69.7 bits (169), Expect = 5e-11
Identities = 76/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 25 CGGTLKGLNGTIESP--GFPYGYPNGA-NCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
C + G +ESP G P G +CT+ I I+I Q+ L +E + L L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 82 YDGHPHPTNFRTRLTGFHLPPP--VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
G R L + S + L S GF+++Y+ S CG
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
P P G + T G + C +GY L G L C+ + SW+ P C A
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCMA-- 277
Query: 200 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
+CGGT+ ++ G I SP N C W I A G + L F ++E D L +
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 258 EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDS 291
G P P I+ S M+ P +IS+ L + ++++
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSET 375
Score = 68.2 bits (165), Expect = 1e-10
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 12/259 (4%)
Query: 24 TCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
+CGGT+ G I SP C WVI A E R+ + F+ +L+E+ D L +
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 83 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
G P + + + ++ +S++ + L S+ + + +E + C
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRFEAFEEDRCFA 396
Query: 141 PGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTASWDFPVPICR 196
P + V + G +SC+ GY L+ G P + C+ W+ P C+
Sbjct: 397 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACK 454
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 256
A CGG + +G++ SP +P Y DC W + + I L + E
Sbjct: 455 A--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 512
Query: 257 IEGSEPPTIWLSGMNIPPP 275
+G P L+ + P P
Sbjct: 513 FDGDGPSARVLAQLRGPQP 531
Score = 67.8 bits (164), Expect = 2e-10
Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 15/188 (7%)
Query: 2718 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC-LA 2774
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 2775 GHCGIPELIVNGQVIGENYGY--RDTVVYQCNPGFRLIGSSVRICQQ----DHNWSGQLP 2828
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 2829 SCV--PVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2882
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 2883 HPPPMCKV 2890
PP+CKV
Sbjct: 753 SQPPLCKV 760
Score = 57.0 bits (136), Expect = 3e-07
Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L G + SP +P Y G +C W + +E RI + + + E D L+L+DG
Sbjct: 457 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 515
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVS----AHGFKVYYEEL-QSSSCG 139
+L G + S+ +L+ + GF ++++E+ ++ +C
Sbjct: 516 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 575
Query: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
P G + D+ G + Y C GY L G LTC + SW P C+
Sbjct: 576 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQK 631
Query: 198 EDACG--GTMRGSSGIISSPSFPNEYHNNADC 227
C G + S FP H C
Sbjct: 632 IMTCADPGEIANGHRTASDAGFPVGSHVQYRC 663
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/136 (32%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 2956 GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 3015
G PG+ P + + G + S T + L QS R + G Q + +
Sbjct: 166 GSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 219
Query: 3016 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKAV 3072
CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA- 277
Query: 3073 QCGNPGTTANGKVFRI 3088
CG GT N + RI
Sbjct: 278 SCG--GTIHNATLGRI 291
Score = 52.8 bits (125), Expect = 6e-06
Identities = 28/63 (44%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C DPGE NG R SD F +GS VQ+ C Y L+GA +TC WSD P C
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 694
Query: 504 KVK 506
+K
Sbjct: 695 ALK 697
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3307 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3365
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 569 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 628
Query: 3366 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3418
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 684
Query: 3419 --WTGKVPIC 3426
W+ +VP C
Sbjct: 685 PKWSDRVPKC 694
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
+C +PG G F VG ++Y C+ GY L+G LTC + T W VP
Sbjct: 634 TCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPK 693
Query: 195 C 195
C
Sbjct: 694 C 694
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 133 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 753
Query: 191 PVPICR 196
P+C+
Sbjct: 754 QPPLCK 759
Score = 43.9 bits (102), Expect = 0.003
Identities = 39/148 (26%), Positives = 56/148 (37%), Gaps = 14/148 (9%)
Query: 1659 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 699 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 756
Query: 1717 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1776
C + V P G N +I +P V+ L V
Sbjct: 757 LCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 807
Query: 1777 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1804
+Y Q SL SGSHS + + S
Sbjct: 808 IYYTKLQGKSLF-GFSGSHSYSPITVES 834
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
Query: 3191 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3247
++C PP+ ++G + T+ G + ++ C GY+L L C+ NGT W+GE P C+
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCM 276
Query: 3248 PKFCG 3252
CG
Sbjct: 277 AS-CG 280
Score = 41.2 bits (95), Expect = 0.019
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2774 AGHCGIPELIVNGQVIGENYG 2794
A G G+++ G
Sbjct: 277 ASCGGTIHNATLGRIVSPEPG 297
Score = 41.2 bits (95), Expect = 0.019
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 619 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 674
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 755
Query: 675 PIC 677
P+C
Sbjct: 756 PLC 758
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3311 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3367
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 219 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3130 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3186
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 273
Query: 3187 TCRAVTCPTPPQISNGRL 3204
+C A T + GR+
Sbjct: 274 SCMASCGGTIHNATLGRI 291
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2777 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSCVPVS 2834
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 278
Query: 2835 CG 2836
CG
Sbjct: 279 CG 280
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 446 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 701 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 758
Query: 504 KV 505
KV
Sbjct: 759 KV 760
Score = 35.8 bits (81), Expect = 0.80
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2833 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2888
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 35.0 bits (79), Expect = 1.4
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 2949 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 3005
+ ++ CG P P + +S G T + C L G+ + C LNG W+G
Sbjct: 214 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGET 272
Query: 3006 PHCSGDATGT 3015
P C GT
Sbjct: 273 PSCMASCGGT 282
Score = 34.3 bits (77), Expect = 2.3
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3370 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3427
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 276
Query: 3428 A 3428
A
Sbjct: 277 A 277
Score = 34.3 bits (77), Expect = 2.3
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 3571 LNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVH 3628
L +++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 771 LEVTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSY 827
Query: 3629 ENNNGQAAFENPMYD 3643
++ F NP+Y+
Sbjct: 828 SPITVESDFSNPLYE 842
Score = 33.1 bits (74), Expect = 5.2
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 2683 FSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2720
F CD GY G ++ CL SW E P C + SCG
Sbjct: 244 FHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASCG 280
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 218 bits (555), Expect = 9e-56
Identities = 201/831 (24%), Positives = 329/831 (39%), Gaps = 191/831 (22%)
Query: 500 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE-- 557
R + + CG LQ +G +SP FP Y S C+W ++ K++ +NF DL
Sbjct: 341 RKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIV-LNFTTMDLYKS 399
Query: 558 --IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 615
YD + + DG P +L G +P+++ S S+MW+ ++ + GF
Sbjct: 400 SLCWYDYIEVRDGYWRKSP--LLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAV 457
Query: 616 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 675
Y+ I CG IR+ +G
Sbjct: 458 YEAI----CGGE------IRKNEG------------------------------------ 471
Query: 676 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 731
+ SP+YP+ Y C+W I + L+F F++E
Sbjct: 472 ---------------QIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCA 516
Query: 732 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 791
+D+L V+DG S SP++G F G + P + S S+ L ++F +D +++ GF +
Sbjct: 517 YDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK-EE 575
Query: 792 NECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
+EC P R G CE+ + T G+ C + C
Sbjct: 576 DECAKPD------RGG------------CEQRCLNTLGSYQCAC---EPGYELGPDRRSC 614
Query: 852 GAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YD 907
A CGG + +G I +PGWP Y + NC W + A + I + FE F+ E N YD
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 908 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 967
+E+ G + S L G + G +VP+ + S N + + F +DN+ S GFK H+
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF------- 727
Query: 968 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1027
+S D +G + + C +G+ L H+ C+ +A C
Sbjct: 728 FSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVL-HDNKHDCK------------EAEC 774
Query: 1028 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1083
+ PSG I SP +P+ YP+ CTW + T G ++ F F +E H +D+L +
Sbjct: 775 EQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEV 834
Query: 1084 TENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1142
+ + P L RL G+ +P + A GN + +RF+SD S+ +GF
Sbjct: 835 FDGETEKSPILGRLCGNKIPDPLVA--TGN-KMFVRFVSDASVQRKGFQ----------- 880
Query: 1143 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1202
T S G RL+ S+ PR +
Sbjct: 881 ---------------------ATHSTECGGRLKAESK---------------PRDLYSHA 904
Query: 1203 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1257
NN Y +C + + + G + +S +TF + + D ++++
Sbjct: 905 QFGDNN------------YPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELF 952
Query: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
DG D T LG F G+ + S + + + F++D +GF + Y S
Sbjct: 953 DGLDSTAVGLGRFCGSGPPE-EIYSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 206 bits (523), Expect = 4e-52
Identities = 177/662 (26%), Positives = 279/662 (42%), Gaps = 144/662 (21%)
Query: 1372 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1427
A CGG + ++ G+I SP YP Y C+W I V V L F +F+ E ++D
Sbjct: 460 AICGGEIR-KNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 1428 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1487
L V DG EN L+ G PE I ST N + ++F +D ++K+GFA F
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKE-EDE 577
Query: 1488 CRDPGVPMNGTRNGDGREPGDTV---VFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
C P R G + +T+ C+PGYEL + R C
Sbjct: 578 CAKPD------RGGCEQRCLNTLGSYQCACEPGYELGPDRRS-----------------C 614
Query: 1545 IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YD 1600
A CGG LT +G I +P +P YP +++C W + Y IS+ F F +E N YD
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1601 FLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRES 1660
++ I+ G S S L G F +++PE I S N M + F+SD +VS GF + + E
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1661 CFDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
D G G ++ +T+ Y C G+VL +
Sbjct: 735 SKDNG--------GCQHECVNTMGSYMCQCRNGFVLH-----------------DNKHDC 769
Query: 1718 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSI-AVPKEFV--VFGQFVF--FQTSLH 1772
A C + G + SPN+P Y C + I A P + F +F Q +
Sbjct: 770 KEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAY 829
Query: 1773 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
D +EV+DG T++S +L L G+ + L +++GN++ +RF S + KGF
Sbjct: 830 DHLEVFDGETEKSPILGRLCGNKIPDPL-VATGNKMFVRFVSDASVQRKGFQ-------A 881
Query: 1833 TSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL---AQWN 1889
T ST+C GR ++ E+ P L AQ+
Sbjct: 882 THSTECG-------GR---------------------------LKAESKPRDLYSHAQFG 907
Query: 1890 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEH- 1948
D+ Y ++C W + G+ +++ +F E
Sbjct: 908 DN--------------------------NYPGQVDCEWLLVSERGSRLELSFQTFEVEEE 941
Query: 1949 ---NWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 2005
+D ++ +DG D+ A LG + G+ P + S +++ ++F +D +++ GFH+ Y
Sbjct: 942 ADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYK 1001
Query: 2006 AI 2007
+I
Sbjct: 1002 SI 1003
Score = 197 bits (500), Expect = 2e-49
Identities = 154/510 (30%), Positives = 227/510 (44%), Gaps = 76/510 (14%)
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
A CGG + + G I SPN+P Y ++C W ITV+ Y + L F SF IE + YD+
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
L + DG NSPLIG F PE I S+SNT+ + F SDG+V+ GF + K + C
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF-FKEEDEC 578
Query: 1662 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
P R G + + +T+ Y C+ GY L G D R SC
Sbjct: 579 AKP------DRGGCEQRCLNTLGSYQCACEPGYEL----------GPDRR--------SC 614
Query: 1719 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFF-----QTSLHD 1773
A CG T GT+ +P +PK Y NCV+ + P ++ + +F FF + +D
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1774 VVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1831
VE++ G + +S L G+ E + S N + I F S ++ KGF HF
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVI-TSQFNNMRIEFKSDNTVSKKGFKAHFF----- 728
Query: 1832 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1891
+ +CS + G + +G S + C G++LH D+
Sbjct: 729 -SDKDECS---KDNGGCQHECVNTMG-SYMCQCRNGFVLH------------------DN 765
Query: 1892 LPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1949
C C + G I SP +P+ Y + C W+I+ G I++ F E +
Sbjct: 766 KHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQ 825
Query: 1950 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY-T 2005
+D L+ +DG +P LG G IP L +T N +++ F SD SV GF + T
Sbjct: 826 ECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885
Query: 2006 AIG--LDSCPEPQTPSSGIKIGDRYMVGDV 2033
G L + +P+ S + GD G V
Sbjct: 886 ECGGRLKAESKPRDLYSHAQFGDNNYPGQV 915
Score = 183 bits (464), Expect = 3e-45
Identities = 141/501 (28%), Positives = 219/501 (43%), Gaps = 62/501 (12%)
Query: 1720 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1774
A CG +EG + SPNYP +Y CV+ I V + + V F F+ HD
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 1775 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1834
+EV DG ++ S L+ G E + S+ N + ++F S G + GF +
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIR-STSNTLWMKFVSDGTVNKAGFAANFFK----E 574
Query: 1835 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
+C+ +R N S C PGY L +
Sbjct: 575 EDECAKPDRGGCEQRCLNTLG---SYQCACEPGYEL------------------GPDRRS 613
Query: 1895 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1950
C CGG+LTK GTI +PG+P+ Y N NCVW++ P I V+ F E N +
Sbjct: 614 CEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKY 673
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010
D ++ + G + + G + G +P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 674 DYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKD 732
Query: 2011 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2070
C + + G + +G + QC G+ L + H C A+
Sbjct: 733 ECSK---DNGGCQHECVNTMGSYMC-QCRNGFVLHDNKH-DCKE--------------AE 773
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLE 2126
C + SG+I SP +P YPS +CTW I+ G + L F F E +D+LE
Sbjct: 774 CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAY---QLQS 2183
V G +E S ++GRL G +IP L +T ++ + F SD S ++GF + +L++
Sbjct: 834 VFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKA 893
Query: 2184 CPDPRPFRNGFVIGNDFTVGQ 2204
PR + G++ GQ
Sbjct: 894 ESKPRDLYSHAQFGDNNYPGQ 914
Score = 181 bits (458), Expect = 2e-44
Identities = 142/469 (30%), Positives = 217/469 (46%), Gaps = 64/469 (13%)
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
A CGG + G I SP +P +Y +C W I + + V L F +F E +DY
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2184
LEVR G+SE S +IGR G P + ST++ + F SD + NK GF + + +
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECA 579
Query: 2185 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2244
+P R G T+G + C PGY L G R CEA CG
Sbjct: 580 ---KPDRGGCEQRCLNTLG-SYQCACEPGYEL----------GPDRR------SCEAACG 619
Query: 2245 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2300
G +T +NGTI +PG+P EYP ++C W V P I + F + E YD++ +W
Sbjct: 620 GLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIW 679
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQPP 2358
G S G+F G E + S N + I+F SD T S GF
Sbjct: 680 SGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGF---------------- 723
Query: 2359 PPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCP 2417
A ++ DE + +++C+ +G+ + CR G L D + C
Sbjct: 724 ----KAHFFSDKDECSKDNGGCQHECV---NTMGSYMCQCRNGFVLH-DNKHDCKEAEC- 774
Query: 2418 ANELRLDS-TGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2472
E ++ S +G+I SP +PD YP+ + C W IS G+ I + F+ E+ +D L
Sbjct: 775 --EQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2521
+V+DG +SP+L L G+ + + G+++F+++ +D +KGF+
Sbjct: 833 EVFDGETEKSPILGRLCGN-KIPDPLVATGNKMFVRFVSDASVQRKGFQ 880
Score = 150 bits (379), Expect = 2e-35
Identities = 130/501 (25%), Positives = 207/501 (41%), Gaps = 63/501 (12%)
Query: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
+A+CGG++R G I SP YP+ Y C W + V+ V F +F +E H +D
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
YL + + S PL R G D P I + + ++F+SD +++ GF F +
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRS---TSNTLWMKFVSDGTVNKAGFAANFFKEE 575
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
+ C P R G + +C GY LG RR C
Sbjct: 576 -DECAKPDRGGCEQRCLNTLG---SYQCACEPGYE---------LGPDRR-------SCE 615
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
A CG T G + +P +P Y N C++ + I++ F L +V K
Sbjct: 616 AACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDY 675
Query: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
I+ G + L G F GA + + ++S N + +EF SD + +GF+ + S +
Sbjct: 676 VEIWSGLSSESKLHGKFCGAEVPEV-ITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1373
+D G Q ++ G + + C G+ LH D AE
Sbjct: 735 SKDNGGCQHEC-VNTMGSY-----MCQCRNGFVLH---------------DNKHDCKEAE 773
Query: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHDIL 1429
C + SG I SP +P Y + C W I PG+ + L F F+ E ++D L
Sbjct: 774 CEQKIH-SPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 1430 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACR 1489
V+DG E +L + G+ IP+ + +T N + ++F +D + + GF S+ +
Sbjct: 833 EVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLK 892
Query: 1490 DPGVP---MNGTRNGDGREPG 1507
P + + GD PG
Sbjct: 893 AESKPRDLYSHAQFGDNNYPG 913
Score = 141 bits (355), Expect = 1e-32
Identities = 121/472 (25%), Positives = 200/472 (42%), Gaps = 102/472 (21%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 563
CG L +GT T+P +P +Y N CVW + A T I + FE F+LE YD +
Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAP-TQYRISVKFEFFELEGNEVCKYDYV 676
Query: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
I G + + G+ VP++I S + M + ++D +V GFK ++ +K+
Sbjct: 677 EIWSG--LSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKDE 733
Query: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 683
C G + + + +C+ GF L K C+E C
Sbjct: 734 CSKDN----GGCQHECVNTMGSYMCQCRNGFVLHDNKHD-CKEAE------------CEQ 776
Query: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKD 739
+P G + SP++P+ Y + C W I + PG RI L+F++F++E +D L V D
Sbjct: 777 KIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFD 836
Query: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 799
G++ +SPILG G N+ PDP +
Sbjct: 837 GETEKSPILGRLCG--------------------------------------NKIPDPLV 858
Query: 800 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHF 859
+ F F +S+ +GF T TE CGG
Sbjct: 859 ATGNKMFV-RFVSDASVQ---RKGFQATHSTE-----------------------CGGRL 891
Query: 860 SAPSGV--ILSPGWPG--YYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEV 911
A S + S G Y ++CEW++ +E G ++++F+ F+ E YD +E+
Sbjct: 892 KAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVEL 951
Query: 912 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV 963
DG + + LG + G+ P+ ++S + + + F TD++ + GF I Y+S+
Sbjct: 952 FDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSI 1003
Score = 135 bits (340), Expect = 7e-31
Identities = 90/304 (29%), Positives = 145/304 (47%), Gaps = 46/304 (15%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 80
CGG L LNGTI +PG+P YP NC W ++A + RI + F+ F LE +YDY+
Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVE 677
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
++ G + + G +P +TS + + SD VS GFK ++ + S
Sbjct: 678 IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKD 737
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
N G + V + C G++L + C+ E
Sbjct: 738 NGGCQHECV------NTMGSYMCQCRNGFVLHDNKH------------------DCK-EA 772
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 255
C + SG+I+SP++P++Y + +CTW I A PG I L F++F++E+ YD+L
Sbjct: 773 ECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 256 EI---EGSEPPTIW-LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
E+ E + P + L G IP P+++ N + + FV+D++ + +GF A TH+
Sbjct: 833 EVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQA--------THS 884
Query: 312 TSTG 315
T G
Sbjct: 885 TECG 888
Score = 115 bits (287), Expect = 1e-24
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 46/302 (15%)
Query: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
EA+CGG I G I SP YPD+Y ++C W + V + + F + E YD
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQLR 2353
++ V DG +NSP IG+F G E + STSN + +KF SD T +GF
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGF----------- 567
Query: 2354 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2411
A E+DE D +CL +G+ C G L D
Sbjct: 568 ---------AANFFKEEDECAKPDRGGCEQRCL---NTLGSYQCACEPGYELGPDRRS-- 613
Query: 2412 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2467
C+ C +L+ G I +PG+P YP + C W + Y I++ EFF+ E
Sbjct: 614 CEAACGGLLTKLN--GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVC 671
Query: 2468 EFDVLQVYDGPNIQSPVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNKKGFRIRY 2524
++D ++++ G + +S L G + A ITS + + +++ +D+ +KKGF+ +
Sbjct: 672 KYDYVEIWSGLSSES----KLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF 727
Query: 2525 IA 2526
+
Sbjct: 728 FS 729
Score = 112 bits (281), Expect = 5e-24
Identities = 82/290 (28%), Positives = 124/290 (42%), Gaps = 36/290 (12%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CGG ++ G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
+ DG + R G+ P + ST + ++ SD V+ GF + + + C
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK-EEDECAK 580
Query: 141 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
P +G + + +C GY L G + +C E A
Sbjct: 581 PD---RGGCEQRCLNTLGSYQCACEPGYEL-GPDRRSC-------------------EAA 617
Query: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYLE 256
CGG + +G I++P +P EY N +C W +VA IS+ F F++E KYDY+E
Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVE 677
Query: 257 IEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
I L G +P I S N +R+ F +D+ +GF A +
Sbjct: 678 IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF 727
Score = 100 bits (250), Expect = 2e-20
Identities = 78/299 (26%), Positives = 132/299 (44%), Gaps = 68/299 (22%)
Query: 498 DHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL- 556
D++ CK C + PSG TSPN+P +Y S +C W I+A ++ I++ F EF++
Sbjct: 764 DNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHR-IKLAFSEFEIE 822
Query: 557 ---EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFK 613
E YD L + DG P +L L G+ +PD +V+ ++M++ +D SV GF+
Sbjct: 823 QHQECAYDHLEVFDGETEKSP--ILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQ 880
Query: 614 VNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 673
+ CG G + D +S+ QFG +NN
Sbjct: 881 ATH----STECG--GRLKAESKPRDLYSH-------AQFG------------DNN----- 910
Query: 674 IPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ-- 731
Y ++C W ++S+ GSR+ LSF F++E +
Sbjct: 911 ---------------------------YPGQVDCEWLLVSERGSRLELSFQTFEVEEEAD 943
Query: 732 --FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
+D++ + DG + LG F G+ P + S + + F D +++ +GF+I Y +
Sbjct: 944 CGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 77.0 bits (188), Expect = 3e-13
Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
L RC A CG + NG + SPG+P+ YP++ C W V V PG I +NFT +
Sbjct: 343 LYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL 401
Query: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS 2335
YD+I V DG + SP +G+F G+ E + ST +++ I+F S
Sbjct: 402 CWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRS 445
Score = 70.1 bits (170), Expect = 4e-11
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
CG + + +G + SPGFP YPS C W +++ G + L F S+ +DY+E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
VR G S ++GR G ++P L ST + F S + +GF VY+A
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 68.6 bits (166), Expect = 1e-10
Identities = 39/112 (34%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CG L S+G + SP FP+ YP C W ++V I L F + + + YD++
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1655
+ DG SPL+G F KLPE + S+ + M + FRS + GF Y+A
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 67.4 bits (163), Expect = 2e-10
Identities = 77/318 (24%), Positives = 109/318 (34%), Gaps = 71/318 (22%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CG TL+ NG + SPGFP GYP+ +C W + +I + F + L + YDY+
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
+ DG+ + R G LP +TST S + S GF YE + CG
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI----CGG 464
Query: 141 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
+G + Y D P C+ W V +E
Sbjct: 465 EIRKNEGQIQS--------------PNYPDDYRPMKECV--------WKITV----SESY 498
Query: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG- 259
G ++ SF E H+N YDYLE+
Sbjct: 499 HVG--------LTFQSFEIERHDNC-------------------------AYDYLEVRDG 525
Query: 260 ---SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 316
+ P G + P I S N L + FV+D GF+A + G
Sbjct: 526 TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGG 585
Query: 317 LEEHNRTTTGAIAVASTP 334
E+ T G+ A P
Sbjct: 586 CEQRCLNTLGSYQCACEP 603
Score = 65.5 bits (158), Expect = 9e-10
Identities = 39/131 (29%), Positives = 68/131 (51%), Gaps = 5/131 (3%)
Query: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
L G + + + +C A CG +G + SPG+P Y +C W + PG I +
Sbjct: 332 LSKGDIAQARKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLN 390
Query: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
F + +++ L YD +EV DG SPLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 391 FTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWV 450
Query: 953 NNGFKIHYESV 963
GF YE++
Sbjct: 451 GKGFAAVYEAI 461
Score = 64.7 bits (156), Expect = 2e-09
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 10/116 (8%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-------WD 1951
CG L + G + SPG+P Y + +C+W+++V G I V++F T +D
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKI---VLNFTTMDLYKSSLCWYD 405
Query: 1952 SLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
++ DG +P LG + G +P +L ST + +++ F+S + GF Y AI
Sbjct: 406 YIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
Score = 63.5 bits (153), Expect = 4e-09
Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 8/130 (6%)
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
ACG T++ S+G +SSP FPN Y + C W + PG+ I L FT + + YDY+
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407
Query: 256 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
E+ P G +P + S + + + F + SN +GF+A Y+
Sbjct: 408 EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIR 467
Query: 312 TSTGELEEHN 321
+ G+++ N
Sbjct: 468 KNEGQIQSPN 477
Score = 62.8 bits (151), Expect = 6e-09
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 2090 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2145
NYP +DC W + G + L F F E +DY+E+ G T+ +GR G
Sbjct: 910 NYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSG 969
Query: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
P ++S ++FH+D + NK+GFHI Y++
Sbjct: 970 PPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 57.0 bits (136), Expect = 3e-07
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 9/122 (7%)
Query: 1365 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1424
Y P+C G ES+G + SPG+P Y + C+W + V PG + L F D
Sbjct: 344 YRCPAC-----GETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYK 398
Query: 1425 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1480
S +D + V DG LL G +PE + ST + + I+F + GFA +
Sbjct: 399 SSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458
Query: 1481 SS 1482
+
Sbjct: 459 EA 460
Score = 57.0 bits (136), Expect = 3e-07
Identities = 34/112 (30%), Positives = 58/112 (51%), Gaps = 10/112 (8%)
Query: 2243 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2294
CGG + A + +YS + YP DC WL+ G+ + ++F + E Y
Sbjct: 887 CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946
Query: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFV 2344
D++ ++DG D + +G+F G+ E +YS + +LI FH+D T + GF +
Sbjct: 947 DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHI 998
Score = 53.9 bits (128), Expect = 3e-06
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 12/115 (10%)
Query: 201 CGGTMRGSS---GIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 252
CGG ++ S + S F N Y DC W +V+E G + L F F++EE+ Y
Sbjct: 887 CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946
Query: 253 DYLEI-EGSEPPTIWLS---GMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
DY+E+ +G + + L G P I S + + +HF TD +GF Y+
Sbjct: 947 DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYK 1001
Score = 53.9 bits (128), Expect = 3e-06
Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 4/94 (4%)
Query: 45 YPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLSLYDGHPHPTNFRTRLTGFHL 100
YP +C W++++E +R+++ FQ+F +EEE YDY+ L+DG R G
Sbjct: 911 YPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGP 970
Query: 101 PPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQ 134
P + S + +D ++ GF + Y+ ++
Sbjct: 971 PEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIR 1004
Score = 53.1 bits (126), Expect = 5e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
R L C A CG S G + SP +P Y +C++ ++V P E +V F +++
Sbjct: 341 RKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKS 399
Query: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
SL +D +EV DG ++S LL G E L S+ +++ I F S KGF VY
Sbjct: 400 SLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVL-TSTDSRMWIEFRSSSNWVGKGFAAVY 458
Query: 1828 QAV 1830
+A+
Sbjct: 459 EAI 461
Score = 50.4 bits (119), Expect = 3e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
CPA E +S G + SPG+P+ YP+ C W +SV G I + K +D
Sbjct: 346 CPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYD 405
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
++V DG +SP+L GD +TS +++++ + KGF Y A
Sbjct: 406 YIEVRDGYWRKSPLLGRFCGDKLPEV-LTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 43.9 bits (102), Expect = 0.003
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2491
++YP C W + E+G + + + F+ E+E +D ++++DG + + L G
Sbjct: 909 NNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGS 968
Query: 2492 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2524
I S G V + + D NKKGF IRY
Sbjct: 969 -GPPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 213 bits (543), Expect = 2e-54
Identities = 179/657 (27%), Positives = 276/657 (42%), Gaps = 134/657 (20%)
Query: 500 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL--- 556
R + K CG LQ +G F++P FP Y S + CVW I+ K++ +NF DL
Sbjct: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIV-LNFTSMDLFKS 401
Query: 557 -EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 615
YD + + DG P +L G +P+ +VS S++W+ ++ ++ GF
Sbjct: 402 RLCWYDYVEVRDGYWRKAP--LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
Query: 616 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 675
Y + +CG G N+D
Sbjct: 460 Y----EATCG-------------GDMNKDA------------------------------ 472
Query: 676 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 731
G + SP+YP+ Y + C+W I G + L+F F++E
Sbjct: 473 --------------GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCA 518
Query: 732 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 791
+D+L V+DG + ES ++G F G E P + S+S+ L ++F +D S++ GF N F
Sbjct: 519 YDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF--AANFFKE 576
Query: 792 -NEC--PDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 848
+EC PD G CE + T G+ C D +
Sbjct: 577 VDECSWPDHG--------------------GCEHRCVNTLGSYKCAC---DPGYELAADK 613
Query: 849 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN--- 905
C CGG + +G I SPGWP Y + NC W + A + I + FE F+ E N
Sbjct: 614 KMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
Query: 906 -YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 964
YD +EV G + + L G + G++ P+ + S SN + + F +DN+ S GF+ H+
Sbjct: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF---- 729
Query: 965 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 1024
+S D +G + + C +GY L HE C+ +
Sbjct: 730 ---FSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWL-HENGHDCK------------E 773
Query: 1025 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDY 1080
A C + GT+ SP +P+ YP+ CTW + T G V+ F+ F +E H +D+
Sbjct: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
Query: 1081 LLITENGSFTQP-LARLTGSDLP-PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
L + + P L R GS P PT+ +G LRF SD S+ +GF S
Sbjct: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASG----SSMFLRFYSDASVQRKGFQAVHS 886
Score = 207 bits (526), Expect = 2e-52
Identities = 172/648 (26%), Positives = 281/648 (43%), Gaps = 126/648 (19%)
Query: 507 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 562
TCG ++ +G SPN+P Y + +CVW IT V+ + + F+ F++E YD
Sbjct: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 621
L + DG + ++ G P+ + S S+++W+ +D S+ GF N+ KE+++
Sbjct: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
Query: 622 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
S D G G +R V +G C + +A+ +C C
Sbjct: 580 CSWPDHG----------GCEHRCV---------NTLGSYKCACDPGYELAADKKMCEVAC 620
Query: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAV 737
T GT+ SP +P+ Y N NC+W +++ RI L F F+LE ++DF+ V
Sbjct: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
Query: 738 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 797
+ G SP++ + G F G+E P +TS S+ +R+EF++D+++S RGF + + +EC
Sbjct: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDEC--- 736
Query: 798 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
A+ G C+ + T G+ C +G + A C
Sbjct: 737 -----AKDNGG-----------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAH 778
Query: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEVHD 913
S+ G + SP WP Y C W I + GH +K+TF F+ E + YD LE++D
Sbjct: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
Query: 914 GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDP 973
GP+ L+P+LG + G++ P +S + ++L F +D S GF+
Sbjct: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ---------------- 882
Query: 974 GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRG 1033
VH S + G RL E + +SH GD
Sbjct: 883 --AVH----------------STECGGRLKAE----VQTKELYSHAQ-------FGDNNY 913
Query: 1034 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF 1089
PS C W + G GV+ F TF +E+ +DY+ +
Sbjct: 914 PS--------------EARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDS 959
Query: 1090 TQP-LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
+ P L R GS L +AG +RF +D +I+ +GF+ ++
Sbjct: 960 SAPRLGRFCGSGPLEEIYSAG----DSLMIRFRTDDTINKKGFHARYT 1003
Score = 194 bits (494), Expect = 1e-48
Identities = 176/644 (27%), Positives = 261/644 (40%), Gaps = 124/644 (19%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CG L ++G +P FP+ YP C W I+V I L F S + + YD++
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
+ DG +PL+G F K+PE + S+ + + + FRS ++ GF Y+A +C
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TC-- 464
Query: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1723
G MN DAG + DD RP C
Sbjct: 465 -GGDMNK-----------------DAGQIQSPN------YPDDYRPS---------KECV 491
Query: 1724 SRSTGSEGTVLSPNYPKNYSVGH-NCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPT 1782
R T SEG + + H +C Y D +EV DGPT
Sbjct: 492 WRITVSEGFHVGLTFQAFEIERHDSCAY----------------------DYLEVRDGPT 529
Query: 1783 QQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVPRTSSTQCSS 1840
++S+L+ G E + SS N++ ++F S G I GF +F + +CS
Sbjct: 530 EESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEV------DECSW 582
Query: 1841 VPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1900
R N S C+PGY L + C V CG
Sbjct: 583 PDHGGCEHRCVNTL---GSYKCACDPGYELAADKKM------------------CEVACG 621
Query: 1901 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFY 1956
G +TK GTI SPG+P+ Y N NCVW++ P I +Q F E N +D ++
Sbjct: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
Query: 1957 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQ 2016
G +A G + G+ P ++ S SNN+ + F+SD +VS GF + + D C +
Sbjct: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAK-- 738
Query: 2017 TPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMS 2076
+ G + G + +C GY L + H C A C +S
Sbjct: 739 -DNGGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCKE--------------AGCAHKIS 781
Query: 2077 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSS 2132
G + SP +P YPS +CTW I+ G V L F F E +D+LE+ G
Sbjct: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
Query: 2133 ETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2176
+ ++GR G + P ++ L F+SD S ++GF V+
Sbjct: 842 SLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
Score = 187 bits (474), Expect = 2e-46
Identities = 144/469 (30%), Positives = 218/469 (46%), Gaps = 64/469 (13%)
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
A CGG M+ +G I SP +P +Y S +C W I + GF V L F F E +DY
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI-VYQAYQLQS 2183
LEVR G +E S +IG G + P + S+++ + F SD S NK GF ++ S
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
Query: 2184 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2243
PD + V T+G + C PGY L + + CE C
Sbjct: 582 WPDHGGCEHRCVN----TLG-SYKCACDPGYELAADKKM----------------CEVAC 620
Query: 2244 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITV 2299
GG IT +NGTI SPG+P EYP ++C W V P I + F V + E YDF+ V
Sbjct: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
Query: 2300 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2357
G ++ G+F G+ E + S SN + ++F SD T S GF
Sbjct: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF--------------- 725
Query: 2358 PPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2416
A ++ DE + +++C+ F G+ + CR G L +G C+
Sbjct: 726 -----RAHFFSDKDECAKDNGGCQHECVNTF---GSYLCRCRNGYWLHENGHD--CKEAG 775
Query: 2417 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2472
A+++ G + SP +PD YP+ + C W+IS G+ + + F+ E+ +D L
Sbjct: 776 CAHKIS-SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHL 834
Query: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2521
++YDGP+ +P+L G + S G +FL++ +D +KGF+
Sbjct: 835 EMYDGPDSLAPILGRFCGSKKPDPTVAS-GSSMFLRFYSDASVQRKGFQ 882
Score = 187 bits (474), Expect = 2e-46
Identities = 137/474 (28%), Positives = 213/474 (44%), Gaps = 73/474 (15%)
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
A CGG++ +G I SPN+P Y S++C W ITV+ + + L F +F IE + YD+
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
L + DGP S LIG F + PE ++SSSN + + F SDGS++ GF + ++ E
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
Query: 1662 F-DPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
+ D G G +++ +T+ Y CD GY L +
Sbjct: 582 WPDHG--------GCEHRCVNTLGSYKCACDPGYELAADKKM------------------ 615
Query: 1718 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV--- 1774
C CG T GT+ SP +PK Y NCV+ + P ++ + QF F+ +DV
Sbjct: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
Query: 1775 --VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAV 1830
VEV G + + L GS + E + S N + + F S ++ +GF HF
Sbjct: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVI-TSQSNNMRVEFKSDNTVSKRGFRAHFF---- 730
Query: 1831 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1890
+ +C+ N F S L C GY LH + C+
Sbjct: 731 --SDKDECAK-DNGGCQHECVNTF---GSYLCRCRNGYWLHEN-GHDCKE---------- 773
Query: 1891 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1949
C ++ +GT+ SP +P+ Y + C W I+ G +++ F E +
Sbjct: 774 ------AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQ 827
Query: 1950 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 2000
+D L+ YDG D+ AP LG + G+ P ++ ++++L F SD SV GF
Sbjct: 828 ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 184 bits (467), Expect = 1e-45
Identities = 137/465 (29%), Positives = 209/465 (44%), Gaps = 59/465 (12%)
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1253
A CG + G + SPNYP +Y + EC++ I V G + ++ + F + + D
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
L++ DG + + L+G F G + + S+SN+LW++F SD GF + E+
Sbjct: 522 LEVRDGPTEESALIGHFCGYE-KPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
Query: 1314 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
C P ++ ++ G + + C+PGY L + C
Sbjct: 580 CSWPDHGGCEHRCVNTLGSYKCA-----CDPGYELAADKKM----------------CEV 618
Query: 1373 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1428
CGG F + +G I SPG+P Y N C+W + +SLQF F+ E + +D
Sbjct: 619 ACGG-FITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 1429 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
+ V G + L GS PE I S N + ++F +D +SK GF F S
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
Query: 1489 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
+D G + N G + + +C GY L E C + A C
Sbjct: 738 KDNGGCQHECVNTFG-----SYLCRCRNGYWLH-ENGHDCKE---------------AGC 776
Query: 1549 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1604
++ G + SPN+P YP R+C W I+ A + + L F F IE + YD L +
Sbjct: 777 AHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEM 836
Query: 1605 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1649
YDGPDS +P++G F SK P+ +S ++M L F SD SV GF
Sbjct: 837 YDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 176 bits (446), Expect = 4e-43
Identities = 138/482 (28%), Positives = 212/482 (43%), Gaps = 60/482 (12%)
Query: 842 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 901
++ G A CGG + +G I SP +P Y+ S C W I G + +TF+ F+
Sbjct: 451 ILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFE 510
Query: 902 TELN----YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFK 957
E + YD LEV DGP S L+G + G + P+ + SSSN +++ F +D S + GF
Sbjct: 511 IERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF- 569
Query: 958 IHYESVTVNTYSCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 1016
N + +D P HG + + +CD GY L+ ++ +
Sbjct: 570 ------AANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-------- 615
Query: 1017 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1076
C+ CGG + +GTI SPG+P+ YP + NC W V + F F LE
Sbjct: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
Query: 1077 H----HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFN 1131
+ +D++ + S L R GS+ P I + N R + F SD ++S GF
Sbjct: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-QSNNMRVE--FKSDNTVSKRGFR 726
Query: 1132 ITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1191
F E +D G Q+ F + C +GY L C G
Sbjct: 727 AHFFSDKDECAKDNGGCQHECVNTFG-----SYLCRCRNGYWLHENGH-DCKEAG----- 775
Query: 1192 APLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1251
C ++ EG L SPN+P Y + EC ++I AG + ++ F + Q
Sbjct: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
Query: 1252 -----DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1306
D L++YDG D +LG F G+ T++S S+ ++L F SD +GFQ V+
Sbjct: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
Query: 1307 TS 1308
++
Sbjct: 886 ST 887
Score = 159 bits (401), Expect = 6e-38
Identities = 156/621 (25%), Positives = 261/621 (42%), Gaps = 115/621 (18%)
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
ACG T++ ++G S+P FPN Y + + C W I PG+ I L FT + + YDY+
Sbjct: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
Query: 256 EIEGS----EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
E+ P G IP P++S + L + F + SN +GF A Y+
Sbjct: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA------- 462
Query: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 371
T G++ + G I + P D +R S+E ++T +
Sbjct: 463 TCGGDMNKD----AGQIQSPNYPDD-----------YRPSKECVWRITVSEGFHVGLTFQ 507
Query: 372 KDGLSPHPA---DTQSTRRRPRHAEQIERTKELAVVTH--RVKKAIDFKSRGFKLFPGKD 426
+ H + D R P T+E A++ H +K D KS +L+
Sbjct: 508 AFEIERHDSCAYDYLEVRDGP--------TEESALIGHFCGYEKPEDVKSSSNRLW---- 555
Query: 427 NSNKFSILNEGGIKTA---SNLCPDPGE---PENGKRIGSDFSLGSTVQFSCDEDYVLQG 480
+++G I A +N + E P++G + + + +CD Y L
Sbjct: 556 ----MKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAA 611
Query: 481 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 540
K + C+V CG + +GT TSP +P +Y +N CVW + A
Sbjct: 612 DKKM------------------CEV-ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVA 652
Query: 541 VNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ 596
+ I + FE F+LE YD + + G + + GS P++I S S+
Sbjct: 653 PAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGSETPEVITSQSNN 709
Query: 597 MWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF-----ECQ 651
M + ++D +V GF+ ++ +K+ C ++ G + V F C+
Sbjct: 710 MRVEFKSDNTVSKRGFRAHFFS-DKDECA---------KDNGGCQHECVNTFGSYLCRCR 759
Query: 652 FGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 711
G+ L E C+E C ++ GT+ SP++P+ Y + C W I
Sbjct: 760 NGYWL-HENGHDCKEAG------------CAHKISSVEGTLASPNWPDKYPSRRECTWNI 806
Query: 712 ISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 767
S G R+ L+FN+F++E +D L + DG +PILG F G++ P ++ +
Sbjct: 807 SSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSM 866
Query: 768 RLEFQADHSMSGRGFNITYNT 788
L F +D S+ +GF ++T
Sbjct: 867 FLRFYSDASVQRKGFQAVHST 887
Score = 143 bits (360), Expect = 4e-33
Identities = 160/648 (24%), Positives = 249/648 (38%), Gaps = 124/648 (19%)
Query: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
+A CGGD+ +G I SP YP+ Y S C W + V+ G V F F +E H +D
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
YL + + + L G + P + + + R ++F+SD SI+ GF F +
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKS---SSNRLWMKFVSDGSINKAGFAANFFK-E 576
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
++ C P R G + +C GY L +A C
Sbjct: 577 VDECSWPDHGGCEHRCVNTLG---SYKCACDPGYEL----------------AADKKMCE 617
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
CG T G + SP +P Y N C++ + A I++ F L DV K
Sbjct: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
+ G L G F G+ + ++S SN + +EF SD + GF+ + S +
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
Query: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGC-NPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
+D G GC + GS L +C G W +
Sbjct: 737 AKDNG---------------------GCQHECVNTFGSYLCRCRNG---YWLHENGHDCK 772
Query: 1373 ECGGRFKGES-SGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHD 1427
E G K S G + SP +P Y + C W I G+ V L F F+ E ++D
Sbjct: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
Query: 1428 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1487
L ++DGP +L GS P+ ++ + + ++F +D + + GF S T
Sbjct: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS----TE 888
Query: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQV-ENRYFWQPSPPVCIA 1546
C GR E+Q +E + Q +N Y PS A
Sbjct: 889 C-------------GGRLKA-----------EVQTKELYSHAQFGDNNY---PSE----A 917
Query: 1547 PCGGNLTGSSGFILSPNF-PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
C + G+ + F DC + DY+ + YD
Sbjct: 918 RCDWVIVAEDGYGVELTFRTFEVEEEADCGY------DYMEA-----------YD----- 955
Query: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1653
G DS++P +G F S E I S+ +++ + FR+D +++ GFH Y
Sbjct: 956 -GYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 113 bits (282), Expect = 4e-24
Identities = 83/313 (26%), Positives = 136/313 (43%), Gaps = 44/313 (14%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 80
CGG + LNGTI SPG+P YP NC W ++A + RI + F+ F LE +YD++
Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
+ G R G P +TS + + SD VS GF+ ++ + +
Sbjct: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYIL--DGHPQLTCIANSVNTASWDFPVPICRA 197
N G + V + C GY L +GH C+
Sbjct: 740 NGGCQHECV------NTFGSYLCRCRNGYWLHENGHD--------------------CK- 772
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
E C + G ++SP++P++Y + +CTW I + G + L F +F++E+ YD
Sbjct: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
Query: 254 YLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY--QGSST 307
+LE+ + P G P P +++ + + L F +D++ + +GF A + +
Sbjct: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGR 892
Query: 308 LTHTTSTGELEEH 320
L T EL H
Sbjct: 893 LKAEVQTKELYSH 905
Score = 111 bits (277), Expect = 2e-23
Identities = 81/292 (27%), Positives = 123/292 (42%), Gaps = 38/292 (13%)
Query: 24 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 79
TCGG + G I+SP +P Y C W I E + + FQ+F +E YDYL
Sbjct: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
Query: 80 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSC 138
+ DG + G+ P V S+ + ++ SD +++ GF +++E+ S
Sbjct: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
Query: 139 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
P G + + +C GY L ++ E
Sbjct: 583 -----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------------CE 617
Query: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 254
ACGG + +G I+SP +P EY N +C W +VA ISL F F++E KYD+
Sbjct: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 255 LEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
+E+ P L G P I S N +R+ F +D+ RGF A +
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF 729
Score = 108 bits (270), Expect = 1e-22
Identities = 83/299 (27%), Positives = 134/299 (44%), Gaps = 40/299 (13%)
Query: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
EA CGG++ G I SP YPD+Y ++C W + V G + + F + E YD
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2353
++ V DGP + S IG F G E V S+SN++ +KF SD +GF
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF----------- 569
Query: 2354 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2411
A E DE D ++C+ +G+ C G L D +
Sbjct: 570 ---------AANFFKEVDECSWPDHGGCEHRCV---NTLGSYKCACDPGYELAAD--KKM 615
Query: 2412 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2467
C+V C +L+ G I SPG+P YP + C W + Y I++ E F+ E
Sbjct: 616 CEVACGGFITKLN--GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
Query: 2468 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
++D ++V G + + + G + ITS + + +++ +D+ +K+GFR + +
Sbjct: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
Score = 87.4 bits (215), Expect = 2e-16
Identities = 72/294 (24%), Positives = 121/294 (41%), Gaps = 68/294 (23%)
Query: 503 CKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----I 558
CK C + GT SPN+P +Y S +C W I++ ++V ++ F EF++E
Sbjct: 771 CKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV-KLTFNEFEIEQHQEC 829
Query: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
YD L + DG + P +L GS PD V+ S M+L +D SV GF+
Sbjct: 830 AYDHLEMYDGPDSLAP--ILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA---- 883
Query: 619 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 678
+ CG G ++ + +S+ QFG +NN
Sbjct: 884 VHSTECG--GRLKAEVQTKELYSH-------AQFG------------DNN---------- 912
Query: 679 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDF 734
Y + C W I+++ G + L+F F++E + +D+
Sbjct: 913 ----------------------YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDY 950
Query: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
+ DG +P LG F G+ + S L + F+ D +++ +GF+ Y +
Sbjct: 951 MEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 70.1 bits (170), Expect = 4e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
L +C A CG + G +PG+P+ YP++ C W + V PG I +NFT +
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFF 2343
YD++ V DG + +P +G+F G+ E + ST +++ ++F S+ GFF
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
Score = 67.8 bits (164), Expect = 2e-10
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
CG + D +G +PGFP YPS C W I++ G + L F + S +DY+E
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
VR G + ++GR G +IP L ST + F S + +GF Y+A
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
Score = 64.7 bits (156), Expect = 2e-09
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CG TL+ G +PGFP GYP+ ++C W I +I + F S L + YDY+
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
+ DG+ R G +P P+ ST S + S + GF YE ++CG
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG 465
Score = 63.9 bits (154), Expect = 3e-09
Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
E CGG M +G I SP++P++Y + +C W I G + L F F++E YD
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 254 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
YLE+ L G P + S+ N L + FV+D + GF+A +
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
Query: 310 HTTSTGELEEHNRTTTGAIAVASTP 334
G E T G+ A P
Sbjct: 581 SWPDHGGCEHRCVNTLGSYKCACDP 605
Score = 63.2 bits (152), Expect = 5e-09
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
L G + + + KC A CG +G +PG+P Y +C W I PG I +
Sbjct: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
Query: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
F + F++ L YD +EV DG +PLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
Query: 953 NNGFKIHYES 962
GF YE+
Sbjct: 453 GKGFFAAYEA 462
Score = 63.2 bits (152), Expect = 5e-09
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 32/208 (15%)
Query: 776 SMSGRGFNITYNTFG---HNEC----------PDPGIPINARRFGDNFQLGSSISVICEE 822
S +G +T+N F H EC PD PI R G + S
Sbjct: 808 STAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVAS----- 862
Query: 823 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAP--SGVILSPGWPG--YYKDS 878
G+ D V G CGG A + + S G Y
Sbjct: 863 ------GSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSE 916
Query: 879 LNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFL 934
C+WVI AE G+ +++TF F+ E YD +E +DG + +P LG + G+ + +
Sbjct: 917 ARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEI 976
Query: 935 FSSSNFIYLLFTTDNSRSNNGFKIHYES 962
+S+ + + + F TD++ + GF Y S
Sbjct: 977 YSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 62.0 bits (149), Expect = 1e-08
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 2243 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2294
CGG + A T +YS + YP+ C W++ G G+ + F + E Y
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT 2338
D++ +DG D ++P++G+F G+ LE +YS + ++I+F +D T
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNL----NCVWKITVPEGAGIQVQVVSFATEHN----W 1950
CGG L T + + DNN C W I +G G+++ +F E +
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2006
D ++ YDG D++APRLG + G+ + S ++L + F++D +++ GFH YT+
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 56.6 bits (135), Expect = 4e-07
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 2090 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2145
NYPS C W I G+GV L F F E +DY+E G ++ +GR G
Sbjct: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
Query: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
++S + F +D + NK+GFH Y + + Q
Sbjct: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
Score = 56.2 bits (134), Expect = 6e-07
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 8/114 (7%)
Query: 25 CGGTLKGLNGTIESPGFPY----GYPNGANCTWVIIAEERNRIQIVFQSFALEEE----Y 76
CGG LK T E YP+ A C WVI+AE+ +++ F++F +EEE Y
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 77 DYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 130
DY+ YDG+ R G + S +R +D ++ GF Y
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 54.7 bits (130), Expect = 2e-06
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 1373 ECGGRFKGESSGRILSPGYPFP---YDNNLRCMWMIEVDPGNIVSLQFLAFDTE----AS 1425
ECGGR K E + L F Y + RC W+I + G V L F F+ E
Sbjct: 888 ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCG 947
Query: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1483
+D + +DG + L GS E I+S + + I+F TD I+K GF +++S+
Sbjct: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005
Score = 51.6 bits (122), Expect = 1e-05
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
R L C A CG + G +P +P Y +CV+ I+V P E +V F F++
Sbjct: 343 RKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKS 401
Query: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
L +D VEV DG +++ LL G E L +S+ +++ + F S I KGF Y
Sbjct: 402 RLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAY 460
Query: 1828 QA 1829
+A
Sbjct: 461 EA 462
Score = 51.2 bits (121), Expect = 2e-05
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1251
L +C A CG + + G +P +P Y + C++ I V G+ I ++ + L +
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 1252 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1306
D +++ DG + LLG F G + L ST ++LW+EF S + +GF Y
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPE-PLVSTDSRLWVEFRSSSNILGKGFFAAY 460
Score = 51.2 bits (121), Expect = 2e-05
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2491
++YP+ C W I E GY + + F+ E+E +D ++ YDG + +P L G
Sbjct: 911 NNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS 970
Query: 2492 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2524
I S G + +++ D NKKGF RY
Sbjct: 971 -GPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 49.3 bits (116), Expect = 7e-05
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Query: 201 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 252
CGG ++ + + S F N Y + A C W IVAE G + L F F++EE+ Y
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 253 DYLE----IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
DY+E + S P G I S + L + F TD +GF A Y
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 47.8 bits (112), Expect = 2e-04
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
CPA E D+TG +PG+P+ YP+ C W ISV G I + K +D
Sbjct: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
++V DG ++P+L GD + S +++++ + KGF Y A
Sbjct: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
Score = 44.3 bits (103), Expect = 0.002
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 1220 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1274
NY + C + I + G G+ ++ RTF + + D ++ YDG D + LG F G+
Sbjct: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
Query: 1275 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
+ S + L + F +D +GF YTS
Sbjct: 972 PLE-EIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 34.7 bits (78), Expect = 1.8
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
+D +E YDG + L GS E + S+G+ + IRF + I KGFH Y
Sbjct: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEI-YSAGDSLMIRFRTDDTINKKGFHARY 1002
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 206 bits (525), Expect = 3e-52
Identities = 122/401 (30%), Positives = 183/401 (45%), Gaps = 21/401 (5%)
Query: 2817 CQQDHNWSG----QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK 2872
C+ D +SG Q+ +C + GS + GN F++N + SC+ GYL
Sbjct: 163 CKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGN-FSYNSSCSISCDRGYLPSSMET 221
Query: 2873 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2932
QC ++ +WS P P C VV C PAN E G+F + T +DC G+ L G+
Sbjct: 222 MQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGA 281
Query: 2933 SVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVL------SGEKYTFGSTVHYSCTGKRS 2986
L C +G WD P C + C P N + +GE +TF S+ +++C
Sbjct: 282 QSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGE-FTFKSSCNFTCEEGFM 340
Query: 2987 LLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDP--GTPGHGSRQESNFRTKSTVRYACDT 3044
L G + C G W+ P C +P G +FR S+ ++C+
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQ 400
Query: 3045 GYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKV----FRIDGTTFSSSVIYS 3100
G++L GS+ C G W +P C+AV+C G V I T+ SS +S
Sbjct: 401 GFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFS 460
Query: 3101 CMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPAN-GLRYGDDYVVGQNVSYMC 3159
C EG+ L G + +CT+ G W+ +P+C ++ C +P + + V G + C
Sbjct: 461 CEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFAC 520
Query: 3160 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS 3200
G+T LNGS RTC G WSG++PTC A T P ++
Sbjct: 521 PEGWT--LNGSAARTCGATGHWSGLLPTCEAPTESNIPLVA 559
Score = 164 bits (415), Expect = 1e-39
Identities = 120/434 (27%), Positives = 174/434 (40%), Gaps = 42/434 (9%)
Query: 3013 TGTCGDPGTPGHGSRQES--NFRTKSTVRYACDTGYI-LHGSEERTCLANGSWTGRQPEC 3069
T C + GHG E+ N+ K CD G+ L + C A S PE
Sbjct: 140 TAACTNTSCSGHGECVETINNYTCK------CDPGFSGLKCEQIVNCTALES-----PEH 188
Query: 3070 KAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3129
++ C +P + +++SS SC GY+ S QC ++G WS +P C
Sbjct: 189 GSLVCSHP----------LGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 3130 IISCGDPGIPANGL----RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVM 3185
++ C PANG + + ++ C+ G+ EL G++ CT +G W
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGF--ELMGAQSLQCTSSGNWDNEK 296
Query: 3186 PTCRAVTCPTPPQISNGRLEGTN-----FDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
PTC+AVTC Q NG + ++ F + S ++ C G+ L PA + C G W+
Sbjct: 297 PTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWT 356
Query: 3241 GEVPQCLPKFCGDPGIPAQG-----KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADG 3295
++P C C P +G SF Y S FSC F+L GS C G
Sbjct: 357 QQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTG 416
Query: 3296 TWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFG-FQVGSVVQFHCKKGHLLQGSTTRTCL 3354
W P C + P ++ G F S F C++G L GST C
Sbjct: 417 EWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECT 476
Query: 3355 PDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCR 3414
W+ P C C P N+ P G + C G+ L G+ R C
Sbjct: 477 SQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTL-NGSAARTCG 535
Query: 3415 SDNTWTGKVPICEA 3428
+ W+G +P CEA
Sbjct: 536 ATGHWSGLLPTCEA 549
Score = 160 bits (405), Expect = 2e-38
Identities = 110/380 (28%), Positives = 160/380 (42%), Gaps = 30/380 (7%)
Query: 2529 CSTPESPPHGYII-SQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVP 2585
C+ ESP HG ++ S G NS +CDRG+ + C S W AP+P
Sbjct: 180 CTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSG----EWSAPIP 235
Query: 2586 ACQAISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2641
AC + C P NG + + T T+ C +G+ L + + C S G W
Sbjct: 236 ACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQ--SLQCTSSGNWD 293
Query: 2642 NHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLP 2701
N P C VTC ++ R + +K+ F+C+ G+ GPA +EC
Sbjct: 294 NEK--PTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTT 351
Query: 2702 NGTWSWRNERPYCQIISCGELPTPPNG--NKIGTQTS---YGSTAIFTCDLGFMLVGSAV 2756
G W+ + P C+ C L P G N + + + YGS+ F+C+ GF+L GS
Sbjct: 352 QGQWT--QQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKR 409
Query: 2757 RECLSSGLWSESETRCLAGHCGIPELIVNGQV------IGENYGYRDTVVYQCNPGFRLI 2810
+C +G W + C A C G V IGE + Y+ + + C GF L
Sbjct: 410 LQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGE-FTYKSSCAFSCEEGFELH 468
Query: 2811 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFN-FNDVVTFSCNIGYLMQG 2869
GS+ C W+ ++PSC V C P S +G F V F+C G+ + G
Sbjct: 469 GSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNG 528
Query: 2870 PTKAQCQANRQWSHPPPMCK 2889
C A WS P C+
Sbjct: 529 SAARTCGATGHWSGLLPTCE 548
Score = 159 bits (402), Expect = 5e-38
Identities = 107/385 (27%), Positives = 159/385 (41%), Gaps = 37/385 (9%)
Query: 2948 PECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRT--CQLNGHWSGSQ 3005
PE + C HP +++ S+ SC R L S T C +G WS
Sbjct: 186 PEHGSLVCSHPL---------GNFSYNSSCSISCD--RGYLPSSMETMQCMSSGEWSAPI 234
Query: 3006 PHCSGDATGTCGDPGTPGHGS----RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 3061
P C+ C P +G + +F +T + C+ G+ L G++ C ++G+
Sbjct: 235 PACN---VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN 291
Query: 3062 WTGRQPECKAVQCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTA 3117
W +P CKAV C NG V TF SS ++C EG++L GP+ +CT
Sbjct: 292 WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTT 351
Query: 3118 NGTWSGTLPNCTIISCGDPGIPANGLRY-----GDDYVVGQNVSYMCQPGYTMELNGSRI 3172
G W+ +P C C P G + G + + C+ G+ L GS+
Sbjct: 352 QGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFV--LKGSKR 409
Query: 3173 RTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN-----FDWGFSISYICSPGYELSF 3227
C G W PTC AV C Q G + + F + S ++ C G+EL
Sbjct: 410 LQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHG 469
Query: 3228 PAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSF-IYQSEVSFSCNFPFILVGS 3286
L C G W+ EVP C C +P + ++ + F+C + L GS
Sbjct: 470 STQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGS 529
Query: 3287 STRICQADGTWSGSSPHCIEPTQTS 3311
+ R C A G WSG P C PT+++
Sbjct: 530 AARTCGATGHWSGLLPTCEAPTESN 554
Score = 94.4 bits (233), Expect = 2e-18
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 22/234 (9%)
Query: 2550 SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI-----L 2604
S + C+ GF L G + C W +P C+A C P G +
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQ----WTQQIPVCEAFQCTALSNPERGYMNCLPSA 384
Query: 2605 TTDYLVGTRVTYFCNDGYRLS-SKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILE 2663
+ + G+ + C G+ L SK L C G W N P C V C +++
Sbjct: 385 SGSFRYGSSCEFSCEQGFVLKGSKRLQ---CGPTGEWDNEK--PTCEAVRCDAVHQ--PP 437
Query: 2664 HGRWRIVNG--SHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGE 2721
G R + + YK+ FSC+ G+ G +EC G W+ E P CQ++ C
Sbjct: 438 KGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWT--EEVPSCQVVKCSS 495
Query: 2722 LPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA 2774
L P N + +G+ F C G+ L GSA R C ++G WS C A
Sbjct: 496 LAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEA 549
Score = 75.5 bits (184), Expect = 9e-13
Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Query: 3266 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3325
+F Y S S SC+ ++ T C + G WS P C + NP N
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQN 258
Query: 3326 TFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGM 3385
F + F C++G L G+ + C W +P C +C+ P + +V
Sbjct: 259 PGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCS 318
Query: 3386 DLPSHGYTLI----YTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
P+ +T +TC+ GF L G + C + WT ++P+CEA + +P
Sbjct: 319 HSPAGEFTFKSSCNFTCEEGFMLQGPAQVE-CTTQGQWTQQIPVCEAFQCTALSNP 373
Score = 57.0 bits (136), Expect = 3e-07
Identities = 103/471 (21%), Positives = 165/471 (35%), Gaps = 115/471 (24%)
Query: 952 SNNGFKIHYESV-TVNTYSC-LDPGI----------------PVHGRRY-GH---DFSIG 989
+N H E V T+N Y+C DPG P HG H +FS
Sbjct: 144 TNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYN 203
Query: 990 STVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPN 1049
S+ S SCD GY S E + C + WS P+P C+ + V P+ G+ E + N
Sbjct: 204 SSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPAN-----GFVECFQN 258
Query: 1050 SLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGL 1109
+ W TF E+ + L G+ ++G
Sbjct: 259 PGSFPWNTTC-----------TFDCEEGFE----------------LMGAQSLQCTSSGN 291
Query: 1110 YGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS-----RIGFNFGIGDTL 1164
+ N + + ++ C PQ GS F +
Sbjct: 292 WDNEKPTCKAVT--------------------CRAVRQPQNGSVRCSHSPAGEFTFKSSC 331
Query: 1165 TFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGIL-LSPNYPLNYE 1222
F+C G+ L+G +++ C G+ W+ +P C A +C A + G + P+ ++
Sbjct: 332 NFTCEEGFMLQGPAQVECTTQGQ--WTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFR 389
Query: 1223 NNHECIYSIQV-------------QAGKGINISARTFHLAQGDVLKIYDGKDKTTHL-LG 1268
C +S + G+ N + V + G + H +G
Sbjct: 390 YGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIG 449
Query: 1269 AFTGASM------RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP-Q 1321
FT S G L ++ LE S + T+E S ++ C +P +
Sbjct: 450 EFTYKSSCAFSCEEGFELHGSTQ---LECTSQGQWTEE-----VPSCQVVKCSSLAVPGK 501
Query: 1322 FGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
S + F G+ + C G+TL+GS+ C G W LP+C A
Sbjct: 502 INMSCSGEPVF-GTVCKFACPEGWTLNGSAARTC--GATGHWSGLLPTCEA 549
Score = 52.4 bits (124), Expect = 8e-06
Identities = 65/276 (23%), Positives = 107/276 (38%), Gaps = 40/276 (14%)
Query: 1681 STVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYP 1739
+T T+ C+ G+ L G +L C + W+ P+C A C + G+V + P
Sbjct: 266 TTCTFDCEEGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVRQPQNGSVRCSHSP 321
Query: 1740 KN-YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSG- 1797
++ +C ++ + F++ G T+ + P ++ ++LS G
Sbjct: 322 AGEFTFKSSCNFTCE--EGFMLQGPAQVECTTQGQWTQQI--PVCEAFQCTALSNPERGY 377
Query: 1798 -ESLPLSSGN---QITIRFTSVGPITAKGFHFVY--------QAVPRTSSTQCSSVPEPR 1845
LP +SG+ + F+ KG + P + +C +V +P
Sbjct: 378 MNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPP 437
Query: 1846 FG------RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVP 1898
G IG EF SS F C G+ LHGS + C S QW + +P+C +V
Sbjct: 438 KGLVRCAHSPIG-EFTYKSSCAFSCEEGFELHGSTQLEC----TSQGQWTEEVPSCQVVK 492
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEG 1934
C + K + G P V K PEG
Sbjct: 493 CSSLAVPGKINMSCSGEPV-----FGTVCKFACPEG 523
Score = 51.2 bits (121), Expect = 2e-05
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 63/251 (25%)
Query: 446 CPDPGEPENG-----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHR 500
C PE G F GS+ +FSC++ +VL+G+K + C E W + +
Sbjct: 367 CTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGE----WDNEK 422
Query: 501 PVCKVKTCGSNLQGPSGTFTSPNFPF-QYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG 559
P C+ C + Q P G + P ++ + C + E F+L G
Sbjct: 423 PTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE------------EGFELH-G 469
Query: 560 YDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEI 619
L G+ + QV+ S + +V K+N
Sbjct: 470 STQLECTSQGQWTEEVPSCQVVKCSSL----------------------AVPGKINM--- 504
Query: 620 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 679
SC G P++G V +F C G+ L G + C WS +P C
Sbjct: 505 ---SCS--GEPVFG----------TVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEA 549
Query: 680 PCLSNFTAPMG 690
P SN G
Sbjct: 550 PTESNIPLVAG 560
Score = 50.4 bits (119), Expect = 3e-05
Identities = 40/154 (25%), Positives = 56/154 (36%), Gaps = 11/154 (7%)
Query: 3291 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGS---QNNTFGFQVGSVVQFHCKKGHLLQG 3347
C+ D +SG I +C P HGS + F S C +G+L
Sbjct: 163 CKCDPGFSGLKCEQI----VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSS 218
Query: 3348 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH---GYTLIYTCQPGFFL 3404
T C+ WS P C C PA+ V P T + C+ GF L
Sbjct: 219 METMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFEL 278
Query: 3405 AGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPR 3438
G + C S W + P C+A + V+ P+
Sbjct: 279 MGAQSLQ-CTSSGNWDNEKPTCKAVTCRAVRQPQ 311
Score = 48.1 bits (113), Expect = 2e-04
Identities = 69/287 (24%), Positives = 97/287 (33%), Gaps = 65/287 (22%)
Query: 462 FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ-------- 513
F +T F C+E + L GA+S+ C W + +P CK TC + Q
Sbjct: 262 FPWNTTCTFDCEEGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVRQPQNGSVRC 317
Query: 514 --GPSGTFT---SPNF----------PFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 558
P+G FT S NF P Q + Q W + + Q + E
Sbjct: 318 SHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWT-QQIPVCEAFQCTALS-NPER 375
Query: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESV--GSVGFKVNY 616
GY L +GSF S + L+ + + G G N
Sbjct: 376 GY--------------MNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNE 421
Query: 617 KEI-EKESCGDPGTPLYGIRE------GDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ 669
K E C P G+ G+ F+ + F C+ GFEL G + C Q
Sbjct: 422 KPTCEAVRCDAVHQPPKGLVRCAHSPIGE-FTYKSSCAFSCEEGFELHGSTQLECTSQGQ 480
Query: 670 WSANIPICIFPCLSNFTAP------------MGTVLSPDYPEGYGNN 704
W+ +P C S+ P GTV PEG+ N
Sbjct: 481 WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLN 527
Score = 46.6 bits (109), Expect = 5e-04
Identities = 64/268 (23%), Positives = 104/268 (38%), Gaps = 32/268 (11%)
Query: 793 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG 852
E P+ G + + G NF SS S+ C+ G++ + ET+ C + G+ WS IP C
Sbjct: 184 ESPEHGSLVCSHPLG-NFSYNSSCSISCDRGYLPS-SMETMQC-MSSGE--WSAPIPACN 238
Query: 853 -APCGGHFSAPSGVI---LSPG-WPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYD 907
C + +G + +PG +P + +CE E S++ T + N+D
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCT-----SSGNWD 293
Query: 908 ----VLEVHDGPNLLSPLLGSYNGTQVP--QFLFSSS-NFI----YLLFTTDNSRSNNGF 956
+ + P GS + P +F F SS NF ++L
Sbjct: 294 NEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQG 353
Query: 957 KIHYESVTVNTYSCLDPGIPVHG-----RRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE 1011
+ + + C P G F GS+ FSC+ G+ L + L C
Sbjct: 354 QWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCG 413
Query: 1012 KNHWWSHPLPTCDAL-CGGDVRGPSGTI 1038
W + PTC+A+ C + P G +
Sbjct: 414 PTGEWDNEKPTCEAVRCDAVHQPPKGLV 441
Score = 45.1 bits (105), Expect = 0.001
Identities = 101/460 (21%), Positives = 145/460 (31%), Gaps = 118/460 (25%)
Query: 446 CPDPGEPENGKRIGS----DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 501
C PE+G + S +FS S+ SCD Y+ +++ C E WS P
Sbjct: 180 CTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE----WSAPIP 235
Query: 502 VCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
C V C + +G P + N C FD E G++
Sbjct: 236 ACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT------------------FDCEEGFE 277
Query: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEK 621
M +Q LQ S K K +
Sbjct: 278 L------------------------------MGAQ---SLQCTSSGNWDNEKPTCKAVTC 304
Query: 622 ESCGDP--GTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC-I 678
+ P G+ F+ + F C+ GF L G + C QW+ IP+C
Sbjct: 305 RAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEA 364
Query: 679 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 738
F C T LS + GY +NC + S GS + S +F E F K
Sbjct: 365 FQC---------TALS-NPERGY---MNC---LPSASGSFRYGSSCEFSCEQGFVLKGSK 408
Query: 739 ----------DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMS---GRGFNIT 785
D + P + + P L +H EF S + GF +
Sbjct: 409 RLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELH 468
Query: 786 YNTFGHNECPDPG-----IP---------------INARRFGDNFQLGSSISVICEEGFI 825
+T EC G +P IN G+ G+ C EG+
Sbjct: 469 GST--QLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPV-FGTVCKFACPEGW- 524
Query: 826 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV 865
G+ TC WSGL+P C AP + +G+
Sbjct: 525 TLNGSAARTC---GATGHWSGLLPTCEAPTESNIPLVAGL 561
Score = 43.1 bits (100), Expect = 0.005
Identities = 96/448 (21%), Positives = 148/448 (33%), Gaps = 100/448 (22%)
Query: 1838 CSSVPEPRFGRRI-----GNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSL 1892
C+++ P G + GN F+ SS C+ GY+ ++C S +W+ +
Sbjct: 180 CTALESPEHGSLVCSHPLGN-FSYNSSCSISCDRGYLPSSMETMQCM----SSGEWSAPI 234
Query: 1893 PTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQ-VQVVSFATEHNW 1950
P C +V C + G + P + N C + EG + Q + + NW
Sbjct: 235 PACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCE--EGFELMGAQSLQCTSSGNW 292
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010
D N P + + + N + S S AG E+T
Sbjct: 293 D---------NEKPTCKAVTCRAVRQPQNGSVR---------CSHSPAG---EFTF--KS 329
Query: 2011 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPI---- 2066
SC +F C++G+ LQG + + C +W IP+
Sbjct: 330 SC----------------------NFTCEEGFMLQGPAQVECTTQG--QWTQQIPVCEAF 365
Query: 2067 --------------CLAQCGGAMSDFSGVILS--PGFPGNYPSSLDC----TWTINLPIG 2106
CL G+ S S GF L C W P
Sbjct: 366 QCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
Query: 2107 FGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2166
V V+ + + VR S IG + S FS L+ +
Sbjct: 426 EAVRCDAVHQPPKGL-----VRCAHSP----IGEFTYKS--SCAFSCEEGFELHGSTQLE 474
Query: 2167 QNKQG-FHIVYQAYQLQSCPDPR-PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC 2224
QG + + Q+ C P + + G F C G+TL G++A TC
Sbjct: 475 CTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTC 534
Query: 2225 LHGVSRNWNHPLPRCEALCGGNITAMNG 2252
G + +W+ LP CEA NI + G
Sbjct: 535 --GATGHWSGLLPTCEAPTESNIPLVAG 560
Score = 43.1 bits (100), Expect = 0.005
Identities = 60/292 (20%), Positives = 100/292 (34%), Gaps = 68/292 (23%)
Query: 1830 VPRTSSTQCSSVPEPRFGR----RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1885
+P + +C +V P G + F ++ FDC G+ L G+ +++C S
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQC----TSS 289
Query: 1886 AQWNDSLPTC-IVPCGGILTKRKGTIL---SPGYPEPYDNNLNCVWKITVPEGAGIQVQV 1941
W++ PTC V C + + G++ SP + ++ N T EG +Q
Sbjct: 290 GNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCN----FTCEEGFMLQGPA 345
Query: 1942 -VSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 2000
V T+ W P ++ T + S Y+N S S
Sbjct: 346 QVECTTQGQW---------TQQIPVCEAFQCTAL-----SNPERGYMNCLPSASGS---- 387
Query: 2001 HLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 2060
+ G F C+QG+ L+G + C GP W
Sbjct: 388 ---------------------------FRYGSSCEFSCEQGFVLKGSKRLQC--GPTGEW 418
Query: 2061 NYPIPICLA-QCGGAMSDFSGVILSPGFP-GNYPSSLDCTWTINLPIGFGVH 2110
+ P C A +C G++ P G + C ++ GF +H
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE--EGFELH 468
Score = 43.1 bits (100), Expect = 0.005
Identities = 49/224 (21%), Positives = 76/224 (33%), Gaps = 63/224 (28%)
Query: 1677 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLS 1735
++ GS+ + C+ G+VL+G L C G G W+ P+C A C + +G V
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQC--GPTGE--WDNEKPTCEAVRCDAVHQPPKGLVRC 443
Query: 1736 PNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSH 1795
+ P G+F + + E ++ H
Sbjct: 444 AHSP---------------------IGEFTYKSSCAFSCEEGFE--------------LH 468
Query: 1796 SGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEP-RFGRRIGNEF 1854
L +S Q T + VP +CSS+ P + E
Sbjct: 469 GSTQLECTSQGQWT------------------EEVPSCQVVKCSSLAVPGKINMSCSGEP 510
Query: 1855 AVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1898
G+ F C G+ L+GS A C + W+ LPTC P
Sbjct: 511 VFGTVCKFACPEGWTLNGSAARTC----GATGHWSGLLPTCEAP 550
Score = 34.7 bits (78), Expect = 1.8
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 2192 NGFVI----GNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGN 2246
NGFV F T +F+C G+ L+G +L C S NW++ P C+A+ C
Sbjct: 250 NGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTS--SGNWDNEKPTCKAVTCRAV 307
Query: 2247 ITAMNGTI 2254
NG++
Sbjct: 308 RQPQNGSV 315
Score = 32.7 bits (73), Expect = 6.8
Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIIS 213
F G +SC G++L G +L C T WD P C A C + G++
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQC----GPTGEWDNEKPTCEAV-RCDAVHQPPKGLVR 442
Query: 214 SPSFP-NEYHNNADCTWT 230
P E+ + C ++
Sbjct: 443 CAHSPIGEFTYKSSCAFS 460
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 202 bits (515), Expect = 4e-51
Identities = 149/496 (30%), Positives = 216/496 (43%), Gaps = 55/496 (11%)
Query: 2679 TKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNK-IGTQTSY 2737
T + + C PGY G P SI CL N W+ ++ C+ SC P P NG + +
Sbjct: 59 TYLNYECRPGYSGR-PFSIICLKNSVWTSAKDK--CKRKSCRNPPDPVNGMAHVIKDIQF 115
Query: 2738 GSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQ---VIGE 2791
S ++C G+ L+GS+ C+ SG +W C CG+P I NG + E
Sbjct: 116 RSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISRE 175
Query: 2792 NYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PVSCGHPG- 2839
+ Y V Y CN G F L+G C + WSG P C+ P C P
Sbjct: 176 YFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNV 235
Query: 2840 -SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGI 2898
+ I + + F+ N+VV F C G+ M+GP+ +CQA +W P C V C P
Sbjct: 236 ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV-CQPPPD 294
Query: 2899 PANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH- 2957
+++R + + NF+ G VFY C PGY L GS+ L C P G W P C + C
Sbjct: 295 VLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDF 353
Query: 2958 -PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDAT 3013
+P VL G+ V + C L G S+ C L G W+ S P C
Sbjct: 354 LGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE---R 410
Query: 3014 GTCGDPGTPGHGS-RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPEC 3069
+C P P +G ++ S + Y+C TG+ L G C+ +G+ W+ + P C
Sbjct: 411 KSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Query: 3070 KAVQCGNPGTTANGKVFRIDGT-----TFSSSVIYSC-------MEGYILSGPSVRQCT- 3116
+ + C NP NG R GT + V Y+C M ++ ++R+ +
Sbjct: 471 QQIFCPNPPAILNG---RHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSE 527
Query: 3117 --ANGTWSGTLPNCTI 3130
NG WS P C +
Sbjct: 528 PHGNGVWSSPAPRCEL 543
Score = 195 bits (496), Expect = 6e-49
Identities = 147/503 (29%), Positives = 206/503 (40%), Gaps = 50/503 (9%)
Query: 2801 YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG-NGFNFNDVVTF 2859
Y+C PG+ S+ IC ++ W+ C SC +P P+ G F + +
Sbjct: 63 YECRPGYSGRPFSI-ICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKY 121
Query: 2860 SCNIGYLMQGPTKAQCQANRQ---WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2916
SC GY + G + A C + W + P+C + C P AN S I F YG
Sbjct: 122 SCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTS-ISREYFHYG 180
Query: 2917 TVVFYDCNPG------YFLFGSSVLICQPN----GQWDKPLPECIMID-CGHPGVPPNAV 2965
+VV Y CN G + L G + C G W P P+CI+ + C P V +
Sbjct: 181 SVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 240
Query: 2966 LSGEK--YTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPG 3023
+S + ++ V + C + G S CQ W P CS C P
Sbjct: 241 VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSR----VCQPPPDVL 296
Query: 3024 HGSRQE---SNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGN-PGT 3079
H R + NF V Y+C+ GY L GS C G W+ P C+ C + G
Sbjct: 297 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQ 356
Query: 3080 TANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDP 3136
NG V + V + C EG+ L G S C G W+ ++P C SC P
Sbjct: 357 LPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETP 416
Query: 3137 GIPANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAVT 3192
+P NG+ + D VG ++Y C G+ L G C ++G WS P C+ +
Sbjct: 417 PVPVNGMVHVITDIHVGSRINYSCTTGH--RLIGHSSAECILSGNTAHWSMKPPICQQIF 474
Query: 3193 CPTPPQISNGRLEGT---NFDWGFSISYICSPGYE--LSFPAVLTCV--------GNGTW 3239
CP PP I NGR GT + +G +SY C P + ++F + GNG W
Sbjct: 475 CPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVW 534
Query: 3240 SGEVPQC-LPKFCGDPGIPAQGK 3261
S P+C LP G GK
Sbjct: 535 SSPAPRCELPVGAGSHDALIVGK 557
Score = 171 bits (433), Expect = 1e-41
Identities = 147/496 (29%), Positives = 204/496 (41%), Gaps = 51/496 (10%)
Query: 2913 FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK-Y 2971
F GT + Y+C PGY S+ IC N W +C C +P P N + K
Sbjct: 55 FPIGTYLNYECRPGYSGRPFSI-ICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDI 113
Query: 2972 TFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPGTPGHG--- 3025
F S + YSC L+G SS TC ++G+ W P C CG P T +G
Sbjct: 114 QFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD---RIICGLPPTIANGDFT 170
Query: 3026 SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECKAVQCG 3075
S F S V Y C+ G + L G C + G W+G P+C
Sbjct: 171 SISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKC 230
Query: 3076 NPGTTANGKVFRIDGTTFSSS--VIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISC 3133
P NG + + + FS + V + C G+ + GPS +C A W LP+C+ +
Sbjct: 231 TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQ 290
Query: 3134 GDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV 3191
P + R D++ GQ V Y C+PGY +L GS CT G WS P C
Sbjct: 291 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY--DLRGSTYLHCTPQGDWSPAAPRCEVK 348
Query: 3192 TCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNG---TWSGEVPQC 3246
+C Q+ NG L N G + ++C G++L + CV G W+ VP C
Sbjct: 349 SCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 408
Query: 3247 LPKFCGDPGIPAQGKREGKSFIY-QSEVSFSCNFPFILVGSSTRICQADGT---WSGSSP 3302
K C P +P G + I+ S +++SC L+G S+ C G WS P
Sbjct: 409 ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPP 468
Query: 3303 HCIEPTQTSCENPGVPRHGSQNNT------FGFQVGSVVQFHCKKG---HLLQGST-TRT 3352
C Q C NP +G T +G +V H +G +L+ ST RT
Sbjct: 469 IC---QQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRT 525
Query: 3353 CLP--DLTWSGIQPEC 3366
P + WS P C
Sbjct: 526 SEPHGNGVWSSPAPRC 541
Score = 160 bits (405), Expect = 2e-38
Identities = 122/398 (30%), Positives = 166/398 (41%), Gaps = 30/398 (7%)
Query: 3056 CLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQC 3115
CL N WT + +CK C NP NG I F S + YSC +GY L G S C
Sbjct: 78 CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC 137
Query: 3116 TANGT---WSGTLPNCTIISCGDPGIPANG--LRYGDDYV-VGQNVSYMCQPG----YTM 3165
+G W P C I CG P ANG +Y G V+Y C G
Sbjct: 138 IISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVF 197
Query: 3166 ELNGSRIRTCTIN----GTWSGVMPTCRAVTCPTPPQISNGRLEGTN---FDWGFSISYI 3218
EL G CT G WSG P C TPP + NG L N F + +
Sbjct: 198 ELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFR 257
Query: 3219 CSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPG---IPAQGKREGKSFIYQSEVSF 3275
C PG+ + P+ + C W E+P C + C P + +R+ +F EV +
Sbjct: 258 CQPGFGMKGPSHVKCQALNKWEPELPSC-SRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 316
Query: 3276 SCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCEN-PGVPRHGSQNNTFGFQVGSV 3334
SC + L GS+ C G WS ++P C SC++ G +G Q+G+
Sbjct: 317 SCEPGYDLRGSTYLHCTPQGDWSPAAPRC---EVKSCDDFLGQLPNGHVLFPLNLQLGAK 373
Query: 3335 VQFHCKKGHLLQGSTTRTCL---PDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHG 3391
V F C +G L+GS+ C+ + W+ P C SC+ P P + V + G
Sbjct: 374 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVG 433
Query: 3392 YTLIYTCQPGFFLAGGTEHRVCRSDNT--WTGKVPICE 3427
+ Y+C G L G + S NT W+ K PIC+
Sbjct: 434 SRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQ 471
Score = 159 bits (403), Expect = 4e-38
Identities = 133/464 (28%), Positives = 193/464 (41%), Gaps = 60/464 (12%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
C P P +G Q S ++++C +G+RL+G SSA C S WD P C
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISG-NTVIWDNKTPVCD 154
Query: 2589 AISCGIPKAPTNGGI--LTTDYL-VGTRVTYFCNDGYRLSSKELTTAV------CQSD-- 2637
I CG+P NG ++ +Y G+ VTY CN G R K++ V C S
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSR--GKKVFELVGEPSIYCTSKDD 212
Query: 2638 --GTWSNHNKTPRCVV---VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGL 2692
G WS P+C++ T P++ + IL N S + V F C PG+
Sbjct: 213 QVGIWS--GPAPQCIIPNKCTPPNVENGILVSD-----NRSLFSLNEVVEFRCQPGFGMK 265
Query: 2693 GPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT-------SYGSTAIFTC 2745
GP+ ++C W E P SC + PP +T S G ++C
Sbjct: 266 GPSHVKC--QALNKWEPELP-----SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSC 318
Query: 2746 DLGFMLVGSAVRECLSSGLWSESETRCLAGHC-GIPELIVNGQVIGE-NYGYRDTVVYQC 2803
+ G+ L GS C G WS + RC C + NG V+ N V + C
Sbjct: 319 EPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVC 378
Query: 2804 NPGFRLIGSSVRIC---QQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG-NGFNFNDVVTF 2859
+ GF+L GSS C + W+ +P C SC P P+ G + + +
Sbjct: 379 DEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINY 438
Query: 2860 SCNIGYLMQGPTKAQCQAN---RQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2916
SC G+ + G + A+C + WS PP+C+ + C +P N R + G+ YG
Sbjct: 439 SCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNG-RHTGTPLGDIPYG 497
Query: 2917 TVVFYDCNP------GYFLFGSSVL--ICQP--NGQWDKPLPEC 2950
V Y C+P + L G S + +P NG W P P C
Sbjct: 498 KEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRC 541
Score = 127 bits (319), Expect = 2e-28
Identities = 107/361 (29%), Positives = 142/361 (39%), Gaps = 40/361 (11%)
Query: 3099 YSCMEGYILSG-PSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVS 3156
Y C GY SG P C N W+ C SC +P P NG+ + D +
Sbjct: 63 YECRPGY--SGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIK 120
Query: 3157 YMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGTN---FD 3210
Y C GY L GS TC I+G W P C + C PP I+NG + F
Sbjct: 121 YSCPKGY--RLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFH 178
Query: 3211 WGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQCL-PKFCGDP----G 3255
+G ++Y C+ G +EL + C G WSG PQC+ P C P G
Sbjct: 179 YGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENG 238
Query: 3256 IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENP 3315
I R F V F C F + G S CQA W P C C+ P
Sbjct: 239 ILVSDNRS--LFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC----SRVCQPP 292
Query: 3316 GVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ 3373
H +Q + F G V + C+ G+ L+GST C P WS P C SC
Sbjct: 293 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDD 352
Query: 3374 --PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICEAG 3429
+ P + ++L G + + C GF L G + + ++ W VP+CE
Sbjct: 353 FLGQLPNGHVLFPLNLQL-GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERK 411
Query: 3430 S 3430
S
Sbjct: 412 S 412
Score = 124 bits (312), Expect = 1e-27
Identities = 133/530 (25%), Positives = 204/530 (38%), Gaps = 73/530 (13%)
Query: 2529 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2584
C+ PE P + T + + + + C G+ G+ S +C K+S W +
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTSAK 88
Query: 2585 PACQAISCGIPKAPTNG-GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2643
C+ SC P P NG + D +++ Y C GYRL T + S T
Sbjct: 89 DKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWD 147
Query: 2644 NKTPRCVVVTC---PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHG------LGP 2694
NKTP C + C P+I +G + ++ ++ Y + V + C+ G G +G
Sbjct: 148 NKTPVCDRIICGLPPTI-----ANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGE 202
Query: 2695 ASIECL--PNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLGF 2749
SI C + W P C I + P NG + S S F C GF
Sbjct: 203 PSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 262
Query: 2750 MLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNPG 2806
+ G + +C + W E E + C P +++ Q +N+ V Y C PG
Sbjct: 263 GMKGPSHVKCQALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG 321
Query: 2807 FRLIGSSVRICQQDHNWSGQLPSCVPVSC---------GHPGSPIYGRTSGNGFNFNDVV 2857
+ L GS+ C +WS P C SC GH P+ V
Sbjct: 322 YDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPL-------NLQLGAKV 374
Query: 2858 TFSCNIGYLMQGPTKAQC---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2914
F C+ G+ ++G + + C W+ P+C+ +C P +P N +
Sbjct: 375 DFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITD---IH 431
Query: 2915 YGTVVFYDCNPGYFLFGSSVLICQPNG---QWDKPLPECIMIDCGHPGVPPNAVLSGE-- 2969
G+ + Y C G+ L G S C +G W P C I C +P N +G
Sbjct: 432 VGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPL 491
Query: 2970 -KYTFGSTVHYSCTGKR------SLLGQSS--RTCQL--NGHWSGSQPHC 3008
+G V Y+C +L+G+S+ RT + NG WS P C
Sbjct: 492 GDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRC 541
Score = 113 bits (283), Expect = 3e-24
Identities = 88/304 (28%), Positives = 125/304 (41%), Gaps = 29/304 (9%)
Query: 3148 DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG- 3206
++ +G ++Y C+PGY+ C N W+ C+ +C PP NG
Sbjct: 54 EFPIGTYLNYECRPGYS---GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVI 110
Query: 3207 TNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCLPKFCGDPGIPAQGKRE 3263
+ + I Y C GY L + TC+ +G W + P C CG P A G
Sbjct: 111 KDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFT 170
Query: 3264 GKS---FIYQSEVSFSCNF------PFILVGSSTRICQAD----GTWSGSSPHCIEPTQT 3310
S F Y S V++ CN F LVG + C + G WSG +P CI P +
Sbjct: 171 SISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNK- 229
Query: 3311 SCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIP 3368
C P V +G +N F + VV+F C+ G ++G + C W P C
Sbjct: 230 -CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC-S 286
Query: 3369 HSCKQPETPAHANVVGMDLP--SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
C+ P HA D S G + Y+C+PG+ L G T + C W+ P C
Sbjct: 287 RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGST-YLHCTPQGDWSPAAPRC 345
Query: 3427 EAGS 3430
E S
Sbjct: 346 EVKS 349
Score = 85.9 bits (211), Expect = 7e-16
Identities = 124/506 (24%), Positives = 183/506 (36%), Gaps = 96/506 (18%)
Query: 2182 QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPLPRC 2239
+SC +P NG + D I + C GY LIG+S+ TC+ G + W++ P C
Sbjct: 94 KSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Query: 2240 EAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY---- 2294
+ + CG T NG S EY ++ G + F ++ IY
Sbjct: 154 DRIICGLPPTIANGDFTS--ISREYFHYGSVVTYHCNLGSRGKKV-FELVGEPSIYCTSK 210
Query: 2295 -DFITVWDGPDQNS--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVL 2345
D + +W GP P + + S++S + + + F G +
Sbjct: 211 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHV 270
Query: 2346 SYHAYQL---------RVCQPPPPVPNAEILTED-DEFEIGDIIRYQCLPGFTLVGNAIL 2395
A RVCQPPP V +AE D D F G + Y C PG+ L G+ L
Sbjct: 271 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYL 330
Query: 2396 TCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA-WSISVEKGY 2454
C + A P C+V + L G +L P NLQ+ A ++G+
Sbjct: 331 HCT--PQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP------LNLQLGAKVDFVCDEGF 382
Query: 2455 NITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHG 2514
+ G + VL + ++S+ +
Sbjct: 383 QL-------------------KGSSASYCVLAGMESLWNSSVPVCERKS----------- 412
Query: 2515 NNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSS 2574
C TP P +G + T + S + ++C G RL+G SSA C S
Sbjct: 413 --------------CETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSG 458
Query: 2575 YGYHAWDAPVPACQAISCGIPKAPTNG---GILTTDYLVGTRVTYFCND------GYRL- 2624
H W P CQ I C P A NG G D G V+Y C+ + L
Sbjct: 459 NTAH-WSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLI 517
Query: 2625 -SSKELTTAVCQSDGTWSNHNKTPRC 2649
S T+ +G WS + PRC
Sbjct: 518 GESTIRRTSEPHGNGVWS--SPAPRC 541
Score = 84.0 bits (206), Expect = 3e-15
Identities = 56/191 (29%), Positives = 94/191 (49%), Gaps = 15/191 (7%)
Query: 2536 PHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIP 2595
P+G+++ QL + V + CD GF+L G S++ C + W++ VP C+ SC P
Sbjct: 358 PNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGM-ESLWNSSVPVCERKSCETP 416
Query: 2596 KAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN-KTPRCVVVT 2653
P NG + + TD VG+R+ Y C G+RL ++A C G ++ + K P C +
Sbjct: 417 PVPVNGMVHVITDIHVGSRINYSCTTGHRLIGH--SSAECILSGNTAHWSMKPPICQQIF 474
Query: 2654 CPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDP------GYHGLGPASIE--CLPNGTW 2705
CP N + +GR Y +V ++CDP ++ +G ++I P+G
Sbjct: 475 CP--NPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNG 532
Query: 2706 SWRNERPYCQI 2716
W + P C++
Sbjct: 533 VWSSPAPRCEL 543
Score = 67.4 bits (163), Expect = 2e-10
Identities = 97/432 (22%), Positives = 157/432 (36%), Gaps = 76/432 (17%)
Query: 1658 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
R+SC +P + +NG + D + S + Y C GY L G S+ TCI+ + W+ P
Sbjct: 93 RKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGN-TVIWDNKTP 151
Query: 1717 SC-HAPCGSRSTGSEG--TVLSPNYPKNYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH 1772
C CG T + G T +S Y SV ++C K F + G+ + TS
Sbjct: 152 VCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKD 211
Query: 1773 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKG-FHFV 1826
D V ++ GP Q + + + + + +S + + F KG H
Sbjct: 212 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVK 271
Query: 1827 YQAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIR 1877
QA+ + CS V +P +R + F+ G V + C PGY L GS +
Sbjct: 272 CQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLH 331
Query: 1878 CETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAG 1936
C W+ + P C + C L G + + P + L EG
Sbjct: 332 C----TPQGDWSPAAPRCEVKSCDDFL----GQLPNGHVLFPLNLQLGAKVDFVCDEGFQ 383
Query: 1937 IQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS 1996
++ S+ +SL +++ P S T P +N + +
Sbjct: 384 LKGSSASYCVLAGMESL-----WNSSVPVCERKSCETPPVPVNGMVHVI----------- 427
Query: 1997 AAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC-MPG 2055
+ I +G R +++ C G+ L GHS C + G
Sbjct: 428 -----------------------TDIHVGSR------INYSCTTGHRLIGHSSAECILSG 458
Query: 2056 PVRRWNYPIPIC 2067
W+ PIC
Sbjct: 459 NTAHWSMKPPIC 470
Score = 58.2 bits (139), Expect = 2e-07
Identities = 107/470 (22%), Positives = 157/470 (33%), Gaps = 101/470 (21%)
Query: 769 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINARRFG-DNFQLGSSIS 817
L ++ SGR F+I + C +P P+N + Q S I
Sbjct: 61 LNYECRPGYSGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIK 120
Query: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC-----GAP---CGGHFSAPSGVILSP 869
C +G+ + G+ + TCI+ V+W P C G P G F++ S
Sbjct: 121 YSCPKGY-RLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHY 179
Query: 870 GWPGYYKDSLNCEW--VIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNG 927
G Y +L V E SI T + Q + PN +P NG
Sbjct: 180 GSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPP-NVENG 238
Query: 928 TQVPQFLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 974
L S + ++ L R GF + H + +N + C P
Sbjct: 239 -----ILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPP 293
Query: 975 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 1031
+H R D FS G V +SC+ GY L L C WS P C+ D
Sbjct: 294 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDF 353
Query: 1032 RG--PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1089
G P+G +L +P +L VD +G Q
Sbjct: 354 LGQLPNGHVL-------FPLNLQLGAKVDFVCDEGFQ----------------------- 383
Query: 1090 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1149
L GS + AG+ +N + + CE P +P
Sbjct: 384 ------LKGSSASYCVLAGMESL-----------------WNSSVPVCERKSCETPPVPV 420
Query: 1150 YGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC 1197
G + + +G + +SC++G+RL G S C L G WS P C
Sbjct: 421 NGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Score = 57.0 bits (136), Expect = 3e-07
Identities = 102/442 (23%), Positives = 157/442 (35%), Gaps = 59/442 (13%)
Query: 1335 STIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSCIAECGGRFKGESSGRILSP---- 1389
S I Y C GY L GSS C+ +G WD P C G ++G S
Sbjct: 117 SQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREY 176
Query: 1390 ---GYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEIS 1446
G Y NL + S+ + D D + +W GP ++ + +
Sbjct: 177 FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKD-----DQVGIWSGPAPQCIIPNKCT 231
Query: 1447 GSLIPEGIHSTLN--IVTIQFDTDFYISKSGFAIQFSSSV---------------ATACR 1489
+ GI + N + ++ +F + GF ++ S V + C+
Sbjct: 232 PPNVENGILVSDNRSLFSLNEVVEFRC-QPGFGMKGPSHVKCQALNKWEPELPSCSRVCQ 290
Query: 1490 DPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1546
P ++ R + D PG V + C+PGY+L+G + C + W P+ P C
Sbjct: 291 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGD---WSPAAPRCEV 347
Query: 1547 PCGGNLTGS--SGFILSP-NFPHPYPHSRDCDWTITV---NADYVISLAFISF--SIEPN 1598
+ G +G +L P N CD + +A Y + S S P
Sbjct: 348 KSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV 407
Query: 1599 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMH-LAFRSDGSVSYTG--FHLEYKA 1655
+ P + ++ D + RI S T H L S +G H K
Sbjct: 408 CERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKP 467
Query: 1656 KLRES--CFDPGNIMNGTRLGM---DYKLGSTVTYYCD------AGYVLQGYSTLTCIMG 1704
+ + C +P I+NG G D G V+Y CD + L G ST+
Sbjct: 468 PICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSE 527
Query: 1705 DDGRPGWNRALPSCHAPCGSRS 1726
G W+ P C P G+ S
Sbjct: 528 PHGNGVWSSPAPRCELPVGAGS 549
Score = 53.1 bits (126), Expect = 5e-06
Identities = 106/477 (22%), Positives = 159/477 (33%), Gaps = 60/477 (12%)
Query: 430 KFSILNEGGIKTASNLCPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQR 488
K S+ K C +P +P NG + D S +++SC + Y L G+ S TC
Sbjct: 80 KNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC-I 138
Query: 489 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 548
I+ W + PVC CG +G FTS + + + + KV +
Sbjct: 139 ISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFE 198
Query: 549 INFE-EFDLEIGYDTLTIGDGGE----VGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQT 603
+ E D + I G + + T V G V D S + +
Sbjct: 199 LVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 258
Query: 604 DESVGSVG------FKVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFEC 650
G G +N E E SC P + R+ D FS + + C
Sbjct: 259 QPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSC 318
Query: 651 QFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSPDYPEGYGNNLNCI 708
+ G++L G + C WS P C +F P G VL P L
Sbjct: 319 EPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP-----LNLQLGAK 373
Query: 709 WTIISDPGSRIHLSFNDFDL--------ESQFDFLAVKDGDSPESPILG---TFTGAEVP 757
+ D G ++ S + + S K ++P P+ G T V
Sbjct: 374 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVG 433
Query: 758 SHLT---SNSHILRLEFQADHSMSGRGFN------ITYNTFGHNECPDPGIPINARRFG- 807
S + + H L A+ +SG + I F CP+P +N R G
Sbjct: 434 SRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIF----CPNPPAILNGRHTGT 489
Query: 808 --DNFQLGSSISVICEEG-----FIKTQGTETI-TCILMDGKVMWSGLIPKCGAPCG 856
+ G +S C+ G TI G +WS P+C P G
Sbjct: 490 PLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVG 546
Score = 52.8 bits (125), Expect = 6e-06
Identities = 28/64 (43%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 134 QSSSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 192
+ SC P VP G+++ T VG +I YSC TG+ L GH CI S NTA W
Sbjct: 409 ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSMKP 467
Query: 193 PICR 196
PIC+
Sbjct: 468 PICQ 471
Score = 46.6 bits (109), Expect = 5e-04
Identities = 95/434 (21%), Positives = 144/434 (33%), Gaps = 90/434 (20%)
Query: 969 SCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPLPTCD 1024
SC +P PV+G + D S + +SC GYRL C W + P CD
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 1025 AL-CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1083
+ CG +G S F+ S+ + GK V F L
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKV------FELVGEPSIYCT 208
Query: 1084 TENG-----SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE---GFNITFS 1135
+++ S P + PP + G+ + L +++ + + GF +
Sbjct: 209 SKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV-VEFRCQPGFGMKGP 267
Query: 1136 EY-------NLEP--------CEDPGIPQYGSRIGF---NFGIGDTLTFSCSSGYRLEGT 1177
+ EP C+ P + R NF G + +SC GY L G+
Sbjct: 268 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 1178 SEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGK 1237
+ + C G WS PRC + S + L N ++ + +Q G
Sbjct: 328 TYLHCTPQGD--WSPAAPRCEVK-------------SCDDFLGQLPNGHVLFPLNLQLGA 372
Query: 1238 GINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1297
++ F +G LK G+S L+ + LW NS
Sbjct: 373 KVD-----FVCDEGFQLK----------------GSSASYCVLAGMES-LW---NSSVPV 407
Query: 1298 TDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKC-M 1356
E CE P +P G GS I Y C G+ L G S +C +
Sbjct: 408 C-----------ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECIL 456
Query: 1357 TGERRAWDYPLPSC 1370
+G W P C
Sbjct: 457 SGNTAHWSMKPPIC 470
Score = 43.9 bits (102), Expect = 0.003
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 131 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
++ + SC NP P G+ + + +I+YSC GY L G TCI S NT WD
Sbjct: 89 DKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWD 147
Query: 190 FPVPIC 195
P+C
Sbjct: 148 NKTPVC 153
Score = 40.8 bits (94), Expect = 0.025
Identities = 104/467 (22%), Positives = 167/467 (35%), Gaps = 76/467 (16%)
Query: 1838 CSSVPEPRFGR-RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1896
C + P+P G + + S + + C GY L GS + C N++ W++ P C
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVI-WDNKTPVCD 154
Query: 1897 -VPCG-------GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEH 1948
+ CG G T G Y NL K V E G + + T
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGK-KVFELVG---EPSIYCTSK 210
Query: 1949 NWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNST---------SNNLYLNFQSDISVSAAG 1999
+ D + + G AP+ + T P++ N S N + F+ G
Sbjct: 211 D-DQVGIWSGP---APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKG 266
Query: 2000 -FHLEYTAIG-----LDSCPEPQTPSSGI-------KIGDRYMVGDVVSFQCDQGYSLQG 2046
H++ A+ L SC P + + D + G V + C+ GY L+G
Sbjct: 267 PSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 326
Query: 2047 HSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIG 2106
+++ C P W+ P C + + DF G + P +P +L ++
Sbjct: 327 STYLHCTPQG--DWSPAAPRCEVK---SCDDFLGQL--PNGHVLFPLNLQLGAKVDFVCD 379
Query: 2107 FGVHLQFVNFSTETIHDYLEVRSGS--------SETSTV-----IGRLSGPQIPSSL-FS 2152
G L+ + S + + + S ET V + ++ + S + +S
Sbjct: 380 EGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYS 439
Query: 2153 TTHETSLYFHSD----YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGN---DFTVGQT 2205
T L HS S N + + Q CP+P NG G D G+
Sbjct: 440 CTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKE 499
Query: 2206 ISFECFPG------YTLIGNSALTCLHGVSRN--WNHPLPRCEALCG 2244
+S+ C P + LIG S + N W+ P PRCE G
Sbjct: 500 VSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVG 546
Score = 40.4 bits (93), Expect = 0.033
Identities = 63/274 (22%), Positives = 101/274 (36%), Gaps = 30/274 (10%)
Query: 1142 CEDPGIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRCVA 1199
C +P P G + + + + +SC GYRL G+S C+ G V W P C
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDR 155
Query: 1200 E-CGASAT--NNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVL 1254
CG T N + +S Y +Y + + C + + + + ++ D +
Sbjct: 156 IICGLPPTIANGDFTSISREY-FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQV 214
Query: 1255 KIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTE-GTDEGFQLVYTSF---- 1309
I+ G + T ++ L S + L+ N E GF + S
Sbjct: 215 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLF-SLNEVVEFRCQPGFGMKGPSHVKCQ 273
Query: 1310 -------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCM 1356
EL C P + D+ +F+ G + Y C PGY L GS+ L C
Sbjct: 274 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCT 333
Query: 1357 TGERRAWDYPLPSCIAECGGRFKGE-SSGRILSP 1389
+ W P C + F G+ +G +L P
Sbjct: 334 --PQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP 365
Score = 37.7 bits (86), Expect = 0.21
Identities = 67/302 (22%), Positives = 102/302 (33%), Gaps = 53/302 (17%)
Query: 792 NECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 848
N+C P + N DN F L + C+ GF +G + C ++ W +
Sbjct: 228 NKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGF-GMKGPSHVKCQALN---KWEPEL 282
Query: 849 PKCGAPCGGHFSAPSGVI-----------LSPGWPGYYKDS----LNCEWVIEAEPGHSI 893
P C C P V+ SPG +Y L + P
Sbjct: 283 PSCSRVC----QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDW 338
Query: 894 KITFERFQTELNYDVLEVHDGPNLLSPL---LGSYNGTQVPQ-FLFSSSNFIYLLFTTDN 949
R + + D L ++L PL LG+ + F S+ Y +
Sbjct: 339 SPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 398
Query: 950 SRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRL---SHE 1005
S N+ + SC P +PV+G + D +GS +++SC +G+RL S
Sbjct: 399 SLWNSSVPV------CERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSA 452
Query: 1006 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
E +L WS P C I P P T D+ +GK V
Sbjct: 453 ECILSGNTAHWSMKPPICQ------------QIFCPNPPAILNGRHTGTPLGDIPYGKEV 500
Query: 1066 QF 1067
+
Sbjct: 501 SY 502
Score = 37.0 bits (84), Expect = 0.36
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 1487 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
+CR+P P+NG + + + + C GY L G TCI N W PVC
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Score = 33.9 bits (76), Expect = 3.0
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 2180 QLQSCPD-PRPFRNGFVIGN-DFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPL 2236
+++SC D NG V+ + +G + F C G+ L G+SA C L G+ WN +
Sbjct: 346 EVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 405
Query: 2237 PRCE-ALCGGNITAMNGTIY 2255
P CE C +NG ++
Sbjct: 406 PVCERKSCETPPVPVNGMVH 425
Score = 32.3 bits (72), Expect = 8.9
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 11/74 (14%)
Query: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
E + SC PP VL+ R F G ++ YSC GY L G L C
Sbjct: 279 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQ--- 335
Query: 185 TASWDFPVPICRAE 198
W P C +
Sbjct: 336 -GDWSPAAPRCEVK 348
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 199 bits (505), Expect = 5e-50
Identities = 166/645 (25%), Positives = 272/645 (42%), Gaps = 122/645 (18%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 563
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
Query: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 683
C P G E + + C G+EL +K C C
Sbjct: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
Query: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 739
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
Query: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 799
G + +S + G F G+E P +TS + +R+EF++D+++S +GF + + +EC
Sbjct: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDEC----- 707
Query: 800 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHF 859
S + C++ + T G+ C G V+ A C
Sbjct: 708 --------------SKDNGGCQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHKV 751
Query: 860 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNYDVLEVHDGP 915
++ SG I SP WP Y C W I + PGH +K+TF Q E YD LEV DG
Sbjct: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
Query: 916 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 975
+ +P+LG + G++ P+ + ++ + ++L F +DNS GF+
Sbjct: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA----------------- 854
Query: 976 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 1035
H G V + SH + GD P
Sbjct: 855 -------SHATECGGQVRADVKTKDLYSHAQ---------------------FGDNNYPG 886
Query: 1036 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSFTQ 1091
G ++C W + G GV+ F TF +E+ +DY+ + + T
Sbjct: 887 G--------------VDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTA 932
Query: 1092 P-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
P L R GS P + + ++F SD +I+ +GF++ ++
Sbjct: 933 PRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
Score = 196 bits (498), Expect = 4e-49
Identities = 134/452 (29%), Positives = 218/452 (48%), Gaps = 56/452 (12%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 2014
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
Query: 2015 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
P ++ + + S++C D GY L P +R C A CG
Sbjct: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
Query: 2073 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2128
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2129 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2188
SG + S + G+ G + P + S + + F SD + +K+GF + + + + D
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD-- 710
Query: 2189 PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNIT 2248
NG + + +C G+ L N H EA C +T
Sbjct: 711 ---NGGCQQDCVNTFGSYECQCRSGFVLHDNK-----HDCK----------EAGCDHKVT 752
Query: 2249 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL----QTEPIYDFITVWDGPD 2304
+ +GTI SP +PD+YP+ ++C W + PG+ + + F + Q E YD + V+DG D
Sbjct: 753 STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRD 812
Query: 2305 QNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2336
+P +G+F G+ E V +T +++ ++F+SD
Sbjct: 813 AKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
Score = 192 bits (489), Expect = 4e-48
Identities = 174/648 (26%), Positives = 270/648 (41%), Gaps = 126/648 (19%)
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1253
A CG + G + SPNYP +Y + CI+ IQV G + ++ ++F + + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
L++ DG +++ L+G + G + STS++LWL+F SD GF + + E+
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 1314 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
C P + ++ G + S C+PGY L +RR C A
Sbjct: 551 CSRPNRGGCEQRCLNTLGSYKCS-----CDPGYEL--------APDKRR--------CEA 589
Query: 1373 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1428
CGG F + +G I SPG+P Y N C+W + +SLQF F+TE + +D
Sbjct: 590 ACGG-FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1429 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
+ V G + L + GS PE I S N + ++F +D +SK GF F S
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
Query: 1489 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
+D G N G + QC G+ L + + C + A C
Sbjct: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLH-DNKHDCKE---------------AGC 747
Query: 1549 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1604
+T +SG I SPN+P YP ++C W I+ + + L F+ IE YD L +
Sbjct: 748 DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEV 807
Query: 1605 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1664
+DG D+ +P++G F SK PE + ++ + M L F SD SV GF + +
Sbjct: 808 FDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATEC------- 860
Query: 1665 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS 1724
G ++ D K T Y A + GD+ PG
Sbjct: 861 -----GGQVRADVK---TKDLYSHAQF------------GDNNYPG-------------- 886
Query: 1725 RSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-----HDVVEVYD 1779
G +C + I + + V F F+ +D +E++D
Sbjct: 887 --------------------GVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
Query: 1780 GPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
G + L GS E + S+G+ + ++F S IT KGFH Y
Sbjct: 927 GYDSTAPRLGRYCGSGPPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 184 bits (468), Expect = 1e-45
Identities = 145/465 (31%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2184
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2185 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2244
RP R G T+G + C PGY L + RCEA CG
Sbjct: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
Query: 2245 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2300
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP 2360
G +S G+F G+ E + S N + ++F SD T S ++ C
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
Query: 2361 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2420
+ + +E QC GF L N + D C +
Sbjct: 713 GCQQDCVNTFGSYEC------QCRSGFVLHDN-----------KHDCKEAGC------DH 749
Query: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF---FQTEKEFDVLQVYD 2476
++G I SP +PD YP+ + C W+IS G+ + + F+E Q E +D L+V+D
Sbjct: 750 KVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFD 809
Query: 2477 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2521
G + ++PVL G + + G +FL++ +D+ +KGF+
Sbjct: 810 GRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 182 bits (463), Expect = 4e-45
Identities = 142/478 (29%), Positives = 212/478 (44%), Gaps = 73/478 (15%)
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1662 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
P R G + + +T+ Y CD GY L P R C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
Query: 1719 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1774
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1775 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1831
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
Query: 1832 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1891
+ +CS + N F S C G++LH D+
Sbjct: 702 -SDKDECSK-DNGGCQQDCVNTFG---SYECQCRSGFVLH------------------DN 738
Query: 1892 LPTCI-VPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1949
C C +T GTI SP +P+ Y + C W I+ G +++ + E
Sbjct: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
Query: 1950 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2004
+D L+ +DG D AP LG + G+ P + +T + ++L F SD SV GF +
Sbjct: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
Score = 166 bits (421), Expect = 3e-40
Identities = 132/466 (28%), Positives = 198/466 (42%), Gaps = 59/466 (12%)
Query: 1720 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1774
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1775 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1834
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1835 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
S E R +G S C+PGY E P+
Sbjct: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
Query: 1895 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1950
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKD 705
Query: 2011 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2070
C + +G D QC G+ L + H C A
Sbjct: 706 EC----SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------AG 746
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDYLE 2126
C ++ SG I SP +P YPS +CTW I+ G V L F+ E+ +D+LE
Sbjct: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2172
V G + V+GR G + P + +T L F+SD S ++GF
Sbjct: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
Score = 160 bits (406), Expect = 2e-38
Identities = 190/717 (26%), Positives = 294/717 (41%), Gaps = 132/717 (18%)
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 256 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE-------A 433
Query: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 371
G++++ G I + P D S V I ++SE V +T ++ ++ + S
Sbjct: 434 ICGGDVKK----DYGHIQSPNYPDDYRPSKVCIWRI-QVSEGFHVGLT-FQSFEIERHDS 487
Query: 372 --KDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 429
D L ++S+ R+ +K D KS +L+
Sbjct: 488 CAYDYLEVRDGHSESSTLIGRYC--------------GYEKPDDIKSTSSRLW------- 526
Query: 430 KFSILNEGGIKTAS---NLCPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAK 482
+++G I A N + E R G + +LGS + SCD Y L K
Sbjct: 527 -LKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGS-YKCSCDPGYELAPDK 584
Query: 483 SITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVN 542
C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 585 R-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA-P 624
Query: 543 TNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQMW 598
T I + F+ F+ E G D D EV T L G F P++I S + M
Sbjct: 625 TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMR 682
Query: 599 LHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIG 658
+ ++D +V GFK ++ + E D G G ++ D + +C+ GF L
Sbjct: 683 VEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQCRSGFVLHD 737
Query: 659 EKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSR 718
K C+E C T+ GT+ SP++P+ Y + C W I S PG R
Sbjct: 738 NKH-DCKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHR 784
Query: 719 IHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQAD 774
+ L+F + D+ESQ +D L V DG ++P+LG F G++ P + + + L F +D
Sbjct: 785 VKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
Query: 775 HSMSGRGFNITYNTFGHNECPDPGIPINA----------RRFGDNFQLGS---SISVICE 821
+S+ +GF ++ T EC G + A +FGDN G ++ E
Sbjct: 845 NSVQRKGFQASHAT----EC---GGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAE 897
Query: 822 EGF-----IKTQGTETITCILMDGKVMWSG---LIPKCGAPCGGHFSAPSGVILSPG 870
EG+ +T E T D ++ G P+ G CG S P + S G
Sbjct: 898 EGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCG---SGPPEEVYSAG 951
Score = 150 bits (379), Expect = 2e-35
Identities = 127/466 (27%), Positives = 200/466 (42%), Gaps = 60/466 (12%)
Query: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 908
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF VN +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-------AVNFF 545
Query: 969 SCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1027
+D P G + + SCD GY L+ ++ C+A C
Sbjct: 546 KEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDK--------------RRCEAAC 591
Query: 1028 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1083
GG + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 1084 TENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1142
+ L + GS+ P I + Y N R + F SD ++S +GF F E
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHFFSDKDECS 708
Query: 1143 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1202
+D G Q F + C SG+ L C G C
Sbjct: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLHDNKH-DCKEAG--------------CD 748
Query: 1203 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1257
T+ G + SPN+P Y + EC ++I G + ++ + D L+++
Sbjct: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
Query: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ 1303
DG+D +LG F G S + + +T ++++L F SD +GFQ
Sbjct: 809 DGRDAKAPVLGRFCG-SKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 145 bits (365), Expect = 9e-34
Identities = 133/479 (27%), Positives = 201/479 (41%), Gaps = 64/479 (13%)
Query: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
++ C P R G + SC GY L RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
+ G + L G F G S + ++S N + +EF SD + +GF+ + S +
Sbjct: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
Query: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1373
+D G Q D + GS C G+ LH + + D+ + S
Sbjct: 708 SKDNGGCQ-----QDCVNTFGSYECQ-CRSGFVLHDNK----HDCKEAGCDHKVTS---- 753
Query: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA----SHDIL 1429
+SG I SP +P Y + C W I PG+ V L F+ D E+ ++D L
Sbjct: 754 --------TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
Query: 1430 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
V+DG +L GS PE + +T + + ++F +D + + G F +S AT C
Sbjct: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG----FQASHATEC 860
Score = 115 bits (287), Expect = 1e-24
Identities = 88/291 (30%), Positives = 126/291 (43%), Gaps = 38/291 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
N G + L + + SC GY L + R E
Sbjct: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 255
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 256 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 113 bits (282), Expect = 4e-24
Identities = 77/291 (26%), Positives = 129/291 (44%), Gaps = 38/291 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 80
CGG L LNG+I SPG+P YP NC W ++A + RI + F F E +YD++
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
+ G + + G P +TS + + SD VS GFK ++ + S
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
N G V + C +G++L + C+ E
Sbjct: 711 NGGCQQDCV------NTFGSYECQCRSGFVLHDNKH------------------DCK-EA 745
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
C + +SG I+SP++P++Y + +CTW I + PG + L F + +E + YD+L
Sbjct: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
Query: 256 EI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
E+ + P G P P+++ + + L F +D++ + +GF A +
Sbjct: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
Score = 100 bits (250), Expect = 2e-20
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2353
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
Query: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
C P +CL +G+ +C G L D C+
Sbjct: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2469
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 2470 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 97.8 bits (242), Expect = 2e-19
Identities = 76/299 (25%), Positives = 134/299 (44%), Gaps = 68/299 (22%)
Query: 498 DHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL- 556
D++ CK C + SGT TSPN+P +Y S +C W I++ ++V ++ F E D+
Sbjct: 737 DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV-KLTFMEMDIE 795
Query: 557 ---EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFK 613
E YD L + DG + P VL GS P+ +++ S+M+L +D SV GF+
Sbjct: 796 SQPECAYDHLEVFDGRDAKAP--VLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Query: 614 VNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 673
++ CG G ++ D +S+ QFG +NN
Sbjct: 854 ASH----ATECG--GQVRADVKTKDLYSH-------AQFG------------DNN----- 883
Query: 674 IPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ-- 731
YP G ++C W I+++ G + L F F++E +
Sbjct: 884 -----------------------YPGG----VDCEWVIVAEEGYGVELVFQTFEVEEETD 916
Query: 732 --FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
+D++ + DG +P LG + G+ P + S + ++F +D +++ +GF++ Y +
Sbjct: 917 CGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 67.8 bits (164), Expect = 2e-10
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 1919 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 1974
Y ++C W I EG G+++ +F E +D ++ +DG D+ APRLG Y G+
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Query: 1975 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2006
P + S +++ + F SD +++ GFHL YT+
Sbjct: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 66.6 bits (161), Expect = 4e-10
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 2090 NYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSSETSTVIGRLSGPQ 2145
NYP +DC W I G+GV L F F T+ +DY+E+ G T+ +GR G
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
P ++S + FHSD + K+GFH+ Y + + Q
Sbjct: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
Score = 65.9 bits (159), Expect = 7e-10
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Query: 2243 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2294
CGG + A T +YS + YP DC W++ G G+ + F + E Y
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGF 2342
D++ ++DG D +P++G++ G+ E VYS + +L+KFHSD T GF
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 969
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2345
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 63.2 bits (152), Expect = 5e-09
Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 45 YPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLSLYDGHPHPTNFRTRLTGFHL 100
YP G +C WVI+AEE +++VFQ+F +EEE YDY+ L+DG+ R G
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Query: 101 PPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 130
P V S ++ SD ++ GF + Y
Sbjct: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 62.8 bits (151), Expect = 6e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 451 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 498
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
Query: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 557
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
Query: 558 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 614
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
Query: 615 NYKEIEKESCGDPGTPLYG 633
Y+ I CG YG
Sbjct: 430 VYEAI----CGGDVKKDYG 444
Score = 62.4 bits (150), Expect = 8e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1655
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 59.7 bits (143), Expect = 5e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2482
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
Query: 2483 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2540
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
Query: 2541 ISQTGGQLNSVVRWACDRGFRL 2562
+ L S + +CD G+ L
Sbjct: 560 EQRCLNTLGS-YKCSCDPGYEL 580
Score = 59.3 bits (142), Expect = 7e-08
Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 254 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
YLE+ SE T+ G P I S + L L FV+D + GF+ +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 310 HTTSTGELEEHNRTTTGAIAVASTP 334
+ G E+ T G+ + P
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCSCDP 576
Score = 58.5 bits (140), Expect = 1e-07
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 953 NNGFKIHYESV 963
GF YE++
Sbjct: 424 GKGFFAVYEAI 434
Score = 57.4 bits (137), Expect = 3e-07
Identities = 36/113 (31%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEEL 133
+ DG R R G LP P+ ST S + S GF YE +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1251
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1252 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Query: 1309 F-------ELSHCEDPGIP 1320
+ H + P P
Sbjct: 434 ICGGDVKKDYGHIQSPNYP 452
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
Query: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1828 QAV 1830
+A+
Sbjct: 432 EAI 434
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1365 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1424
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1425 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1478
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 50.1 bits (118), Expect = 4e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Query: 201 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 252
CGG +R + + S F N Y DC W IVAE G + L+F F++EE+ Y
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 253 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
DY+E+ + + P G P + S + + + F +D +GF Y
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 49.3 bits (116), Expect = 7e-05
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2491
++YP C W I E+GY + + + F+ E+E +D ++++DG + +P L G
Sbjct: 882 NNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS 941
Query: 2492 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2524
+ S G V +++ +D KKGF +RY
Sbjct: 942 -GPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 45.4 bits (106), Expect = 0.001
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 1220 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1274
NY +C + I + G G+ + +TF + + D ++++DG D T LG + G+
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 1275 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
S+ + L ++F+SD T +GF L YTS
Sbjct: 943 PPEEVYSAGDSVL-VKFHSDDTITKKGFHLRYTS 975
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 1027 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1082
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1083 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1120
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Score = 38.9 bits (89), Expect = 0.095
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
Query: 2531 TPESPPHGYIIS 2542
+G+I S
Sbjct: 437 GDVKKDYGHIQS 448
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 [Homo
sapiens]
Length = 809
Score = 194 bits (494), Expect = 1e-48
Identities = 153/558 (27%), Positives = 245/558 (43%), Gaps = 31/558 (5%)
Query: 2178 AYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLP 2237
AY L PRP +G V D G T +F C GY L G L CL+G +WN P
Sbjct: 171 AYLLSCGFPPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETP 229
Query: 2238 RCEALCGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDF 2296
C A CGG I A G I SP C W++ G ++++F + + D
Sbjct: 230 SCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDR 289
Query: 2297 ITVWDGPDQNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRV 2354
+ V G SP I + E + S + + ++ S+ + + L + A++
Sbjct: 290 LMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 349
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTL----VGNAILTCRLGERLQMDGAPP 2410
C P + + + T D E+ G + + CLPG+ L NAI C + P
Sbjct: 350 CF-APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEP 407
Query: 2411 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2470
C+ +C EL + GV+LSP +P SY Q C W + V++ I + VE +E D
Sbjct: 408 ACKAMC-GGELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGD 464
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
+L ++DG + VL L G + S+G ++ LQ+ A G G ++ +
Sbjct: 465 MLTLFDGDGPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 523
Query: 2531 TPES-------PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2581
P + PP + + G L +V+ + C+ G+ L+G C+ +W
Sbjct: 524 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWS 579
Query: 2582 APVPACQAI-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDG 2638
A PACQ I +C P NG +D + VG+ V Y C GY L + T + G
Sbjct: 580 AAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTG 639
Query: 2639 TWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIE 2698
T ++ P+C + P +N + E+G ++ + HY+ + F C G+ +G +I
Sbjct: 640 TPKWSDRVPKCALKYEPCLNPGVPENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTIT 698
Query: 2699 CLPNGTWSWRNERPYCQI 2716
C+P W ++ P C++
Sbjct: 699 CVPGHPSQWTSQPPLCKV 716
Score = 192 bits (487), Expect = 7e-48
Identities = 168/681 (24%), Positives = 278/681 (40%), Gaps = 87/681 (12%)
Query: 1481 SSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPS 1540
S + +C P P +G + PG T F CD GY+LQGEE + C+ R W
Sbjct: 169 SPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGE 227
Query: 1541 PPVCIAPCGGNLTGSS-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1599
P C+A CGG + ++ G I+SP + C W I + L F S++ +
Sbjct: 228 TPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 287
Query: 1600 DFLYIYDGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1658
D L + G SP+I +PER + S + ++++ S+ + L ++A
Sbjct: 288 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEE 347
Query: 1659 ESCFDP----GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGW 1711
+ CF P GN+ T +Y+ G+ T+ C GY L+ + + C+ D P W
Sbjct: 348 DRCFAPFLAHGNV---TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHW 402
Query: 1712 NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL 1771
N P+C A CG + G VLSP++P++YS G +CV+ + V +E + Q
Sbjct: 403 NDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE 462
Query: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVY 1827
D++ ++DG + +L+ L G L LSSG +T++F + P +GF +
Sbjct: 463 GDMLTLFDGDGPSARVLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHF 521
Query: 1828 QAVPRTSSTQCSSVPEPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1885
+ VPR + C +P P +G R + + G+ + + C PGY L GS + C
Sbjct: 522 KEVPRNDT--CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC------- 572
Query: 1886 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SF 1944
QW+ S C I+T ++ G+ D P G+ +Q + + +
Sbjct: 573 -QWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGY 623
Query: 1945 ATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2004
+ E A L YS D +
Sbjct: 624 SLE--------------GAAMLTCYS--------------------RDTGTPKWSDRVPK 649
Query: 2005 TAIGLDSCPEPQTPSSGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2062
A+ + C P P +G + Y G+ + F C +G+ L G ITC+PG +W
Sbjct: 650 CALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTS 709
Query: 2063 PIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF------GVHLQFVNF 2116
P+C + + + P + I LP+G GV++ +
Sbjct: 710 QPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKL 769
Query: 2117 STETIHDYLEVRSGSSETSTV 2137
+++ + SGS S +
Sbjct: 770 QGKSLFGF----SGSHSYSPI 786
Score = 180 bits (456), Expect = 3e-44
Identities = 157/595 (26%), Positives = 249/595 (41%), Gaps = 74/595 (12%)
Query: 969 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDAL 1026
SC P P HG D G T +F CDSGY+L EE L+C W+ P+C A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 234
Query: 1027 CGGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1085
CGG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRS 294
Query: 1086 NGSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCED 1144
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C
Sbjct: 295 GGSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 352
Query: 1145 PGIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAE 1200
P + + + G TFSC GY LE + I C+ W+ P C A
Sbjct: 353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 412
Query: 1201 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK 1260
CG + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGD 472
Query: 1261 DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CE 1315
+ +L G R LSS L L+F + G +GF L + + C
Sbjct: 473 GPSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 531
Query: 1316 DPGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IA 1372
+ P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 532 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIM 589
Query: 1373 ECGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRV 1431
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 590 TCADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT--- 638
Query: 1432 WDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDP 1491
P +D + K A+++ C +P
Sbjct: 639 -GTPKWSDRVPK--------------------------------CALKYE-----PCLNP 660
Query: 1492 GVPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
GVP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 661 GVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 714
Score = 174 bits (440), Expect = 2e-42
Identities = 152/596 (25%), Positives = 233/596 (39%), Gaps = 73/596 (12%)
Query: 2011 SCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2069
SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C+A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 233
Query: 2070 QCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2128
CGG + + + G I+SP G +L C W I G +HL F S + +D L VR
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 2129 SGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDP 2187
SG S S VI +P L S + S+ N + ++A++ C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 2188 RPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCEAL 2242
+G V D + G +F C PGY L +A+ C+ +WN P C+A+
Sbjct: 354 F-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 412
Query: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2302
CGG ++ G + SP +P Y QDC W V V I + +L D +T++DG
Sbjct: 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLFDG 471
Query: 2303 PDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRVCQ 2356
++ + Q G + S+ + ++F + GF + + C
Sbjct: 472 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 531
Query: 2357 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2416
PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 532 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ--- 586
Query: 2417 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2476
+ CA + G+ ++ F V
Sbjct: 587 -----------------------KIMTCADPGEIANGHRTA-------SDAGFPV----- 611
Query: 2477 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CSTPE 2533
G ++Q Y + G + +S D G K R+ A C P
Sbjct: 612 GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 661
Query: 2534 SPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 662 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCK 715
Score = 161 bits (407), Expect = 1e-38
Identities = 145/598 (24%), Positives = 236/598 (39%), Gaps = 78/598 (13%)
Query: 1838 CSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1897
C P P G + G + F C+ GY L G + C + + WN P+C+
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSCMA 233
Query: 1898 PCGGILTKRK-GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1956
CGG + G I+SP NL C W I EG + + + + + D L
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 1957 DGGDNNAPRLGSYSGTTIPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEP 2015
GG +P + +P L S + +LY+ S+ + L + A D C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 2016 QTPSSGIKIGD-RYMVGDVVSFQCDQGYSLQ---GHSHITCMPGPVRRWNYPIPICLAQC 2071
+ D Y G + +F C GY+L+ + I C+ WN P C A C
Sbjct: 354 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 413
Query: 2072 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2131
GG +S+ +GV+LSP +P +Y DC W +++ + LQ V D L + G
Sbjct: 414 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQ-VEILNVREGDMLTLFDGD 472
Query: 2132 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNK----QGFHIVY-QAYQLQSCPD 2186
++ V+ +L GPQ L S+ + +L F + QGF + + + + +CP+
Sbjct: 473 GPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 532
Query: 2187 PRPFRNGFVIGN--DFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-- 2242
P G+ + D G ++++C PGY L+G+ LTC +S W+ P C+ +
Sbjct: 533 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLS--WSAAPPACQKIMT 590
Query: 2243 CG--GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2300
C G I + T G+P G ++ + L P Y
Sbjct: 591 CADPGEIANGHRTASDAGFP------------------VGSHVQYRCL---PGYSL---- 625
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKF----HSDFTTSGFFVLSYHAYQLRVCQ 2356
+ + + +S +T + +K+ + +G+ L H YQ
Sbjct: 626 ----EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQ----- 676
Query: 2357 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
G+ +R+ C GF L+G +TC G Q PP+C+V
Sbjct: 677 ------------------AGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 716
Score = 155 bits (391), Expect = 9e-37
Identities = 115/438 (26%), Positives = 186/438 (42%), Gaps = 18/438 (4%)
Query: 623 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFP 680
SCG P P +G F C G++L GE++++C + W+ P C+
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 234
Query: 681 CLSNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 739
C A +G ++SP+ G NL C W I + G R+HL F L+ D L V+
Sbjct: 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRS 294
Query: 740 GDSPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 798
G SP SP++ +VP L S++ L +E ++ + ++ + F + C P
Sbjct: 295 GGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF 354
Query: 799 IPI-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCG 856
+ N ++ G+ + C G+ ++ G + + W+ P C A CG
Sbjct: 355 LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCG 414
Query: 857 GHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 916
G S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 415 GELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDG 473
Query: 917 LLSPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLD 972
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 474 PSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPE 532
Query: 973 PGIPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG 1028
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 533 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCA 592
Query: 1029 --GDVRGPSGTILSPGYP 1044
G++ T G+P
Sbjct: 593 DPGEIANGHRTASDAGFP 610
Score = 148 bits (373), Expect = 1e-34
Identities = 122/456 (26%), Positives = 189/456 (41%), Gaps = 25/456 (5%)
Query: 1311 LSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
L C P P G +S G T + C+ GY L G L C+ G R +W+ PSC
Sbjct: 173 LLSCGFPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Query: 1371 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR 1430
+A CGG + GRI+SP NL C W+IE G + L F + +D L
Sbjct: 232 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 291
Query: 1431 VWDGPPENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACR 1489
V G ++ + +PE G+ S + ++ ++ + +++F + C
Sbjct: 292 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 351
Query: 1490 DPGVPM-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCI 1545
P + N T PG F C PGY L+ I C+ + W + P C
Sbjct: 352 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACK 410
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
A CGG L+ +G +LSP++P Y +DC W + V + I L ++ D L ++
Sbjct: 411 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLF 469
Query: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ES 1660
DG ++ ++ + + R+ SS + L F++ GF L +K R ++
Sbjct: 470 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 529
Query: 1661 C--FDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
C P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPAC 585
Query: 1719 H-----APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1749
A G + G T +P V + C+
Sbjct: 586 QKIMTCADPGEIANGHR-TASDAGFPVGSHVQYRCL 620
Score = 145 bits (367), Expect = 6e-34
Identities = 164/663 (24%), Positives = 249/663 (37%), Gaps = 86/663 (12%)
Query: 1660 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH 1719
SC P +G D G T T++CD+GY LQG TL C+ G RP WN PSC
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCM 232
Query: 1720 APCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---HDVV 1775
A CG + G ++SP +VG N + F + SL +D +
Sbjct: 233 ASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 1776 EVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSS 1835
V G + S ++ E +S + + S P ++A
Sbjct: 291 MVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF---EE 347
Query: 1836 TQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQWND 1890
+C + P G E+ G+ F C PGY L AI C V + WND
Sbjct: 348 DRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPHWND 404
Query: 1891 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1950
+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 405 TEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNVREG 463
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLEYTA 2006
D L +DG +A L G L S+ +L L FQ+ GF L +
Sbjct: 464 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 523
Query: 2007 IGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 2063
+ D+CPE P G + + G V+++QC+ GY L G +TC W+
Sbjct: 524 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAA 581
Query: 2064 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2123
P C I++ PG + P+G H+Q+ ++
Sbjct: 582 PPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYSLEG 627
Query: 2124 YLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2183
+ S +T T K + A + +
Sbjct: 628 AAMLTCYSRDTGTP-------------------------------KWSDRVPKCALKYEP 656
Query: 2184 CPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC-- 2239
C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P C
Sbjct: 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 716
Query: 2240 ---EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWL---VRVPPGNGIYINFTVLQTEPI 2293
E L + T P E N L + + G+G+YI +T LQ + +
Sbjct: 717 AYEELLDNRKLEVTQTT--DPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSL 774
Query: 2294 YDF 2296
+ F
Sbjct: 775 FGF 777
Score = 122 bits (307), Expect = 5e-27
Identities = 105/424 (24%), Positives = 179/424 (42%), Gaps = 32/424 (7%)
Query: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
C P P +G +D G T F CD Y LQG +++ C + +W+ P C +
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-M 232
Query: 506 KTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
+CG + + G SP N C WVI A + + ++FE L+ D L
Sbjct: 233 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLM 291
Query: 565 IGDGGEVGDPRTVLQVLTGSFVPDL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 620
+ GG P V+ S + D+ ++S + +++ L ++ + + ++ E
Sbjct: 292 VRSGGSPLSP-----VIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 346
Query: 621 KESCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELI---GEKSIVCQENNQ--WSANI 674
++ C P + D + + F C G+ L +I C + + W+
Sbjct: 347 EDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTE 406
Query: 675 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDF 734
P C C + P G VLSPD+P+ Y +C+W + RI L ++ + D
Sbjct: 407 PACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDM 465
Query: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFG 790
L + DGD P + +L G + L S+ L L+FQA + G+GF + +
Sbjct: 466 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 525
Query: 791 HNE-CPDPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 847
N+ CP+ P R + L G+ ++ CE G+ + G++ +TC + WS
Sbjct: 526 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAA 581
Query: 848 IPKC 851
P C
Sbjct: 582 PPAC 585
Score = 94.7 bits (234), Expect = 1e-18
Identities = 60/170 (35%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 3148 DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV-TCPTPPQISNGRLEG 3206
D + G ++Y C+PGY EL GS I TC + +WS P C+ + TC P +I+NG
Sbjct: 547 DLIRGTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA 604
Query: 3207 TN--FDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKF--CGDPGIPA 3258
++ F G + Y C PGY L A+LTC G WS VP+C K+ C +PG+P
Sbjct: 605 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 664
Query: 3259 QGKREGKSFIYQS--EVSFSCNFPFILVGSSTRICQA--DGTWSGSSPHC 3304
G + YQ+ + F C F L+G T C W+ P C
Sbjct: 665 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 88.2 bits (217), Expect = 1e-16
Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 16/189 (8%)
Query: 3015 TCGDPGTPGHGSRQESN--FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC-KA 3071
TC + P G R S+ + + Y C+ GY L GS+ TC + SW+ P C K
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 3072 VQCGNPGTTANGKVFRID-GTTFSSSVIYSCMEGYILSGPSVRQCTANGT----WSGTLP 3126
+ C +PG ANG D G S V Y C+ GY L G ++ C + T WS +P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 3127 NCTI--ISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN--GT 3180
C + C +PG+P NG + Y Y G+++ + C G+ EL G TC
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGF--ELIGEVTITCVPGHPSQ 706
Query: 3181 WSGVMPTCR 3189
W+ P C+
Sbjct: 707 WTSQPPLCK 715
Score = 84.0 bits (206), Expect = 3e-15
Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 2892 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2951
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 527 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 586
Query: 2952 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 3004
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 587 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 646
Query: 3005 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 3060
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 647 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 705
Query: 3061 SWTGRQPECK 3070
WT + P CK
Sbjct: 706 QWTSQPPLCK 715
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3192 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3248
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 3249 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3302
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 3303 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3359
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 649 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 707
Query: 3360 SGIQPEC 3366
+ P C
Sbjct: 708 TSQPPLC 714
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2796 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2851
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 550 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 609
Query: 2852 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2905
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 610 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 669
Query: 2906 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2950
H + G + + C G+ L G + C P QW P C
Sbjct: 670 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 68.2 bits (165), Expect = 1e-10
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 12/259 (4%)
Query: 24 TCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
+CGGT+ G I SP C WVI A E R+ + F+ +L+E+ D L +
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 83 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
G P + + + ++ +S++ + L S+ + + +E + C
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRFEAFEEDRCFA 352
Query: 141 PGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTASWDFPVPICR 196
P + V + G +SC+ GY L+ G P + C+ W+ P C+
Sbjct: 353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACK 410
Query: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 256
A CGG + +G++ SP +P Y DC W + + I L + E
Sbjct: 411 A--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 468
Query: 257 IEGSEPPTIWLSGMNIPPP 275
+G P L+ + P P
Sbjct: 469 FDGDGPSARVLAQLRGPQP 487
Score = 67.8 bits (164), Expect = 2e-10
Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 15/188 (7%)
Query: 2718 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC-LA 2774
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 2775 GHCGIPELIVNGQVIGENYGY--RDTVVYQCNPGFRLIGSSVRICQQ----DHNWSGQLP 2828
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 2829 SCV--PVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2882
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 708
Query: 2883 HPPPMCKV 2890
PP+CKV
Sbjct: 709 SQPPLCKV 716
Score = 60.5 bits (145), Expect = 3e-08
Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 10/161 (6%)
Query: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
SCG P P G + T G + C +GY L G L C+ + SW+ P C
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCM 232
Query: 197 AEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYL 255
A +CGGT+ ++ G I SP N C W I A G + L F ++E D L
Sbjct: 233 A--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 256 EI-EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDS 291
+ G P P I+ S M+ P +IS+ L + ++++
Sbjct: 291 MVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSET 331
Score = 57.0 bits (136), Expect = 3e-07
Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
CGG L G + SP +P Y G +C W + +E RI + + + E D L+L+DG
Sbjct: 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 471
Query: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVS----AHGFKVYYEEL-QSSSCG 139
+L G + S+ +L+ + GF ++++E+ ++ +C
Sbjct: 472 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 531
Query: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
P G + D+ G + Y C GY L G LTC + SW P C+
Sbjct: 532 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQK 587
Query: 198 EDACG--GTMRGSSGIISSPSFPNEYHNNADC 227
C G + S FP H C
Sbjct: 588 IMTCADPGEIANGHRTASDAGFPVGSHVQYRC 619
Score = 52.8 bits (125), Expect = 6e-06
Identities = 28/63 (44%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C DPGE NG R SD F +GS VQ+ C Y L+GA +TC WSD P C
Sbjct: 591 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 650
Query: 504 KVK 506
+K
Sbjct: 651 ALK 653
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3307 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3365
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 525 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 584
Query: 3366 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3418
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 585 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 640
Query: 3419 --WTGKVPIC 3426
W+ +VP C
Sbjct: 641 PKWSDRVPKC 650
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/77 (40%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 3015 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKA 3071
+CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA 233
Query: 3072 VQCGNPGTTANGKVFRI 3088
CG GT N + RI
Sbjct: 234 -SCG--GTIHNATLGRI 247
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 137 SCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
+C +PG G F VG ++Y C+ GY L+G LTC + T W VP
Sbjct: 590 TCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPK 649
Query: 195 C 195
C
Sbjct: 650 C 650
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 133 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 652 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 709
Query: 191 PVPICR 196
P+C+
Sbjct: 710 QPPLCK 715
Score = 43.9 bits (102), Expect = 0.003
Identities = 39/148 (26%), Positives = 56/148 (37%), Gaps = 14/148 (9%)
Query: 1659 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 655 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 712
Query: 1717 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1776
C + V P G N +I +P V+ L V
Sbjct: 713 LCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 763
Query: 1777 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1804
+Y Q SL SGSHS + + S
Sbjct: 764 IYYTKLQGKSLF-GFSGSHSYSPITVES 790
Score = 43.1 bits (100), Expect = 0.005
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 9/99 (9%)
Query: 3161 PGYTMELNGSRIRTCTINGTWSGVMPTCRA----VTCPTPPQISNGRLEGTNFDWGFSIS 3216
PG + G T T T + V T + ++C PP+ ++G + T+ G + +
Sbjct: 140 PGPPLGPEGGEEETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTAT 199
Query: 3217 YICSPGYELSFPAVLTCVGNGT---WSGEVPQCLPKFCG 3252
+ C GY+L L C+ NGT W+GE P C+ CG
Sbjct: 200 FHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMAS-CG 236
Score = 41.2 bits (95), Expect = 0.019
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Query: 2774 AGHCGIPELIVNGQVIGENYG 2794
A G G+++ G
Sbjct: 233 ASCGGTIHNATLGRIVSPEPG 253
Score = 41.2 bits (95), Expect = 0.019
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 619 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 674
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 652 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 711
Query: 675 PIC 677
P+C
Sbjct: 712 PLC 714
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3311 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3367
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 175 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3130 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3186
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 229
Query: 3187 TCRAVTCPTPPQISNGRL 3204
+C A T + GR+
Sbjct: 230 SCMASCGGTIHNATLGRI 247
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2777 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD--HNWSGQLPSCVPVS 2834
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 234
Query: 2835 CG 2836
CG
Sbjct: 235 CG 236
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 446 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 714
Query: 504 KV 505
KV
Sbjct: 715 KV 716
Score = 35.8 bits (81), Expect = 0.80
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2833 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2888
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 174 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Score = 34.7 bits (78), Expect = 1.8
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 4/67 (5%)
Query: 2952 MIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQPHC 3008
++ CG P P + +S G T + C L G+ + C LNG W+G P C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGETPSC 231
Query: 3009 SGDATGT 3015
GT
Sbjct: 232 MASCGGT 238
Score = 34.3 bits (77), Expect = 2.3
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3370 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3427
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 232
Query: 3428 A 3428
A
Sbjct: 233 A 233
Score = 34.3 bits (77), Expect = 2.3
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 3571 LNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVH 3628
L +++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 727 LEVTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSY 783
Query: 3629 ENNNGQAAFENPMYD 3643
++ F NP+Y+
Sbjct: 784 SPITVESDFSNPLYE 798
Score = 33.1 bits (74), Expect = 5.2
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 2683 FSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2720
F CD GY G ++ CL SW E P C + SCG
Sbjct: 200 FHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASCG 236
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 193 bits (490), Expect = 3e-48
Identities = 234/902 (25%), Positives = 362/902 (40%), Gaps = 115/902 (12%)
Query: 2587 CQAISCGIPKAPTNGGILTTD-----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2641
C A C N ILT Y GT+ Y C GYR + VC+ G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIM--VCRK-GEWV 72
Query: 2642 NHNKTPRCVVVTC--PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASI-E 2698
N +C C P F G + + G+ +EY K V++C+ GY LG + E
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPF----GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRE 128
Query: 2699 CLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGT------QTSYGSTAIFTCDLGFMLV 2752
C +G W N+ P C+++ C + P NG + + + +G F C+ G+ +
Sbjct: 129 CDTDG---WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 2753 GSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDT--VVYQCNPGFRLI 2810
G C G WS+ + +C+ C P+ ++NG I + Y++ Y+CN G+
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPD-VINGSPISQKIIYKENERFQYKCNMGYEYS 244
Query: 2811 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSP--------IYGRTSGNGFNFNDVVTFSCN 2862
+C + W LPSC SC +P P I RT D +T+ C
Sbjct: 245 ERGDAVCTES-GWR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRT-------GDEITYQCR 295
Query: 2863 IGY--LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF--TYGTV 2918
G+ +G T A+C + W P P C + C P I + F G
Sbjct: 296 NGFYPATRGNT-AKC-TSTGWI-PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 2919 VFYDCNPGYFLFGSSV---LICQPNGQWDKPLPECIMIDCGHP----GVPPNAVLSGEKY 2971
Y C+ + S + C +G W +P C+ C P G N G K+
Sbjct: 353 YSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLR-KCYFPYLENGYNQN---HGRKF 406
Query: 2972 TFGSTVHYSC-TGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTP---GHGSR 3027
G ++ +C G Q++ TC NG WS + P C TC G S
Sbjct: 407 VQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT-PRCI--RVKTCSKSSIDIENGFISE 462
Query: 3028 QESNFRTKSTVRYACDTGYILHGSEER---TCLANGSWTGRQPECKAVQCGNPGTTANGK 3084
+ + K +Y C GY+ E TC +G W+ QP C C P N +
Sbjct: 463 SQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDG-WSA-QPTC-IKSCDIP-VFMNAR 518
Query: 3085 VFRIDGTTF--SSSVIYSCMEGYILSGPSVR---QCTANGTWSGTLPNCTIISCGDPGIP 3139
+ D T F + ++ Y C +GY + S C NG WS LP C C P I
Sbjct: 519 T-KNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELPKID 575
Query: 3140 ANGL--RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR--AVTCPT 3195
+ + R D Y VG+ + + C+PG+T + G C G S +P C+ +C
Sbjct: 576 VHLVPDRKKDQYKVGEVLKFSCKPGFT--IVGPNSVQCYHFGL-SPDLPICKEQVQSCGP 632
Query: 3196 PPQISNGRL-EGTNFDWGFS--ISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL--PKF 3250
PP++ NG + E T ++G S + Y C+P + + P + CV +G W+ +P C+
Sbjct: 633 PPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT-TLPVCIVEEST 690
Query: 3251 CGDPGIPAQGKREGKS--FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPT 3308
CGD G + S + Y V F+C+ F ++G + C G W+ P C+
Sbjct: 691 CGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT-QLPQCVAID 748
Query: 3309 Q-TSCENPG-VPRHGSQNNTFGFQVGSVVQFHC--KKGHLLQGSTTRTCLPDLTWSGIQP 3364
+ C++ + N F S +++ C K+G + P++ S Q
Sbjct: 749 KLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQI 808
Query: 3365 ECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVP 3424
+ P P+ P N+ G + CQ + + G E + D W +P
Sbjct: 809 QLCP---PPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE--ITCKDGRWQ-SIP 862
Query: 3425 IC 3426
+C
Sbjct: 863 LC 864
Score = 180 bits (456), Expect = 3e-44
Identities = 235/915 (25%), Positives = 356/915 (38%), Gaps = 111/915 (12%)
Query: 2554 WACDRGFRLVGKSSAVCRKSSYGYHAWDA--PVPACQAISCGIPKAPTNGGILTTD---Y 2608
+ C G+R +G VCRK W A P+ CQ CG P G T +
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-----WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 2609 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWR 2668
G + Y CN+GY+L E+ C +DG W+ N P C VV C + + E+G +
Sbjct: 105 EYGVKAVYTCNEGYQLLG-EINYRECDTDG-WT--NDIPICEVVKCLPVTA--PENG--K 156
Query: 2669 IVNGS-----HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELP 2723
IV+ + Y + V F C+ GY G + C +G WS E+P C ISC + P
Sbjct: 157 IVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWS--KEKPKCVEISC-KSP 213
Query: 2724 TPPNGNKIGTQTSYGSTAIF--TCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPE 2781
NG+ I + Y F C++G+ C SG W + C C P
Sbjct: 214 DVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLPS-CEEKSCDNP- 270
Query: 2782 LIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPG 2839
I NG +R D + YQC GF W P C C +P
Sbjct: 271 YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI-PAPRCTLKPCDYPD 329
Query: 2840 SPIYGRTSGNGFNFNDVVTFSCNIG--YLMQGPTKAQCQANRQWSHPPPMCKVVNCS--- 2894
G N F +G Y + + W H ++C+
Sbjct: 330 IKHGGLYHENMRR----PYFPVAVGKYYSYYCDEHFETPSGSYWDH-------IHCTQDG 378
Query: 2895 -DPGIPANSK-------RESKIEHG-NFTYGTVVFYDCNPGYFL-FGSSVLICQPNGQWD 2944
P +P K HG F G + C+PGY L + + C NG W
Sbjct: 379 WSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-W- 436
Query: 2945 KPLPECIMI-DCGHPGVP-PNAVLSGEKYTFG--STVHYSC-TGKRSLLGQSSR--TCQL 2997
P P CI + C + N +S +YT+ Y C G + G++S TC
Sbjct: 437 SPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGK 496
Query: 2998 NGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTVRYACDTGYILH-GSEERT 3055
+G WS +QP C +C P ++ + F+ T+ Y C GY + GS +
Sbjct: 497 DG-WS-AQPTC----IKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGS 550
Query: 3056 CLANGSWTGRQPECKAVQCGNPGTTANGKVFR-IDGTTFSSSVIYSCMEGYILSGPSVRQ 3114
+ + P C +C P + R D + +SC G+ + GP+ Q
Sbjct: 551 IVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQ 610
Query: 3115 CTANGTWSGTLPNC--TIISCGDPGIPANG---LRYGDDYVVGQNVSYMCQPGYTMELNG 3169
C G S LP C + SCG P NG + ++Y + V Y C P + M+ G
Sbjct: 611 CYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMK--G 667
Query: 3170 SRIRTCTINGTWSGVMPTC--RAVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYEL 3225
C ++G W+ +P C TC P++ +G +L + +G S+ + CS + +
Sbjct: 668 PNKIQC-VDGEWT-TLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTM 725
Query: 3226 SFPAVLTCVGNGTWSGEVPQCLP----KFCGDPG--IPAQGKREGKSFIYQSEVSFSCNF 3279
+TC+ +G W+ ++PQC+ K C I + + K F + S + + C
Sbjct: 726 IGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRG 783
Query: 3280 PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC 3339
G +C +G W + Q P +P + T ++ G V C
Sbjct: 784 K---EGWIHTVC-INGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLC 839
Query: 3340 KKGHLLQGSTTRTCLPDLTWSGIQPECIPH-SCKQPETPAHANV----VGMDLPSHGYTL 3394
++ +L+Q TC D W I P C+ C QP H + + +HG L
Sbjct: 840 QENYLIQEGEEITC-KDGRWQSI-PLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKL 897
Query: 3395 IYTCQPGFFLAGGTE 3409
YTC+ GF ++ E
Sbjct: 898 SYTCEGGFRISEENE 912
Score = 178 bits (451), Expect = 1e-43
Identities = 192/691 (27%), Positives = 286/691 (41%), Gaps = 99/691 (14%)
Query: 2547 QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAP-VPAC--QAISCGIPKAPTNGGI 2603
++ V++++C GF +VG +S C YH +P +P C Q SCG P NG +
Sbjct: 588 KVGEVLKFSCKPGFTIVGPNSVQC------YHFGLSPDLPICKEQVQSCGPPPELLNGNV 641
Query: 2604 ---LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVV--TCPSIN 2658
+Y V Y+CN + + V DG W+ P C+V TC I
Sbjct: 642 KEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV---DGEWTT---LPVCIVEESTCGDIP 695
Query: 2659 SFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2718
LEHG W ++ Y Y V F+C + +G SI C+ +G W+ + P C ++
Sbjct: 696 E--LEHG-WAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT---QLPQC--VA 746
Query: 2719 CGELPTPPNGNKIGTQTSYGSTAIF--TCDLGFMLVGSA--VRECLSSGLWSESETRCLA 2774
+L + N I + + F ++ + G + +G W + E C
Sbjct: 747 IDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRW-DPEVNCSM 805
Query: 2775 GH---CGIPELIVNGQVIGENYGYRD--TVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2829
C P I N + YRD V C + LI I +D W +P
Sbjct: 806 AQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQS-IPL 863
Query: 2830 CVP-VSCGHPGSPIYG-----RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2883
CV + C P +G R+S + ++++C G+ + + C + WS
Sbjct: 864 CVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGK-WSS 922
Query: 2884 PPPMCKVVNCSDPGIPANSKRESKIEHG-------NFTYGTVVFYDCNPGYFLFGSSVLI 2936
PP C+ + C P +I HG ++ YG V Y C G+ + G ++
Sbjct: 923 PP-QCEGLPCKSP---------PEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAK 972
Query: 2937 CQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK---YTFGSTVHYSCTGKRSLLGQSSR 2993
C +W P P CI DC NA+ GEK Y G V Y+C + G S+
Sbjct: 973 CLGE-KWSHP-PSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNV 1030
Query: 2994 TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHG 3050
TC +N W+G +P C + C +P T + SRQ S + + VRY C + Y + G
Sbjct: 1031 TC-INSRWTG-RPTCRDTS---CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFG 1085
Query: 3051 SEERTCLANGSWTGRQPECK--AVQCGNPGTTANGKV--FRIDGTTFSSSVIYSCMEGYI 3106
EE CL NG+WT P+CK +CG P NG + F + +SSV Y C Y
Sbjct: 1086 DEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQ 1143
Query: 3107 LSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPAN---GLRYGDDYVV----GQNVSYMC 3159
L G C NG WS P C I N LR+ + G++V ++C
Sbjct: 1144 LEGNKRITC-RNGQWSEP-PKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVC 1201
Query: 3160 QPGYTMELNGSRIRTCTINGTWSGVM--PTC 3188
+ GY + +RT W G + PTC
Sbjct: 1202 KRGYRLSSRSHTLRTT----CWDGKLEYPTC 1228
Score = 173 bits (439), Expect = 2e-42
Identities = 250/946 (26%), Positives = 365/946 (38%), Gaps = 131/946 (13%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVR--WACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPA 2586
C P P G G V+ + C+ G++L+G+ + W +P
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTNDIPI 140
Query: 2587 CQAISCGIPKAPTNGGILTT------DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2640
C+ + C AP NG I+++ +Y G V + CN GY++ E C DG W
Sbjct: 141 CEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDE--EMHCSDDGFW 198
Query: 2641 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH------YEYKTKVVFSCDPGYHGLGP 2694
S + P+CV ++C S + ++NGS Y+ + + C+ GY
Sbjct: 199 S--KEKPKCVEISCKSPD----------VINGSPISQKIIYKENERFQYKCNMGYEYSER 246
Query: 2695 ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFM-L 2751
C +G WR P C+ SC + P PNG+ + + G + C GF
Sbjct: 247 GDAVCTESG---WR-PLPSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPA 301
Query: 2752 VGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENY--GYRDTVV-----YQCN 2804
+C S+G W + RC C P+ I +G + EN Y V Y C+
Sbjct: 302 TRGNTAKCTSTG-WIPA-PRCTLKPCDYPD-IKHGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 2805 PGFRLIGSSV---RICQQDHNWSGQLPSCVPVSCGHPG-SPIYGRTSGNGFNFNDVVTFS 2860
F S C QD WS +P C+ C P Y + G F + +
Sbjct: 359 EHFETPSGSYWDHIHCTQD-GWSPAVP-CLR-KCYFPYLENGYNQNHGRKFVQGKSIDVA 415
Query: 2861 CNIGY-LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG--T 2917
C+ GY L + T C N WS P +V CS I + I +TY
Sbjct: 416 CHPGYALPKAQTTVTCMEN-GWSPTPRCIRVKTCSKSSIDIEN---GFISESQYTYALKE 471
Query: 2918 VVFYDCNPGYFLFG---SSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGE--KYT 2972
Y C GY S + C +G W P CI C P V NA + +
Sbjct: 472 KAKYQCKLGYVTADGETSGSITCGKDG-WSAQ-PTCIK-SCDIP-VFMNARTKNDFTWFK 527
Query: 2973 FGSTVHYSC-TGKRSLLGQS--SRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGH--GSR 3027
T+ Y C G S G + S C NG WS P C C P H R
Sbjct: 528 LNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPIC---YERECELPKIDVHLVPDR 582
Query: 3028 QESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK--AVQCGNPGTTANGKV 3085
++ ++ ++++C G+ + G C G + P CK CG P NG V
Sbjct: 583 KKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNV 641
Query: 3086 FRIDGTTFSSS--VIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI--ISCGDPGIPAN 3141
+ S V Y C +++ GP+ QC +G W+ TLP C + +CGD IP
Sbjct: 642 KEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWT-TLPVCIVEESTCGD--IPE- 696
Query: 3142 GLRYG------DDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPT 3195
L +G Y G +V + C +TM G R TC I+G W+ +P C A+
Sbjct: 697 -LEHGWAQLSSPPYYYGDSVEFNCSESFTM--IGHRSITC-IHGVWT-QLPQCVAIDKLK 751
Query: 3196 PPQISNGRL------EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3248
+ SN + FD +I Y C G E V C+ NG W EV +
Sbjct: 752 KCKSSNLIILEEHLKNKKEFDHNSNIRYRCR-GKEGWIHTV--CI-NGRWDPEVNCSMAQ 807
Query: 3249 -KFCGDPGIPAQGKREGKSFIYQ--SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCI 3305
+ C P + Y+ +VS C +++ C+ DG W S P C+
Sbjct: 808 IQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRWQ-SIPLCV 865
Query: 3306 EPTQTSCENPGVPRHGSQNNTFGFQV----GSVVQFHCKKGHLLQGSTTRTCLPDLTWSG 3361
E + C P HG+ N++ Q G+ + + C+ G + TC WS
Sbjct: 866 E--KIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMG-KWSS 922
Query: 3362 IQPECIPHSCKQPETPAHANVVGM-DLPSHGYTLIYTCQPGFFLAG 3406
P+C CK P +H V M D +G + Y C GF + G
Sbjct: 923 -PPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDG 967
Score = 171 bits (433), Expect = 1e-41
Identities = 228/950 (24%), Positives = 384/950 (40%), Gaps = 125/950 (13%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK-SSAVCRKSSYGYHAWDAPVPAC 2587
C P P Y + + + + C GF + ++A C + + P P C
Sbjct: 267 CDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGW------IPAPRC 320
Query: 2588 QAISCGIPKAPTNGGILTTDY-------LVGTRVTYFCNDGYRLSSKELTTAV-CQSDGT 2639
C P +GG+ + VG +Y+C++ + S + C DG
Sbjct: 321 TLKPCDYPDIK-HGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG- 378
Query: 2640 WSNHNKTPRCVVVTCPSI-NSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYH-GLGPASI 2697
WS P P + N + HGR + V G + +C PGY ++
Sbjct: 379 WSP--AVPCLRKCYFPYLENGYNQNHGR-KFVQGKSIDV------ACHPGYALPKAQTTV 429
Query: 2698 ECLPNGTWSWRNERPYC-QIISCGELPTP-PNGNKIGTQTSYG--STAIFTCDLGFMLVG 2753
C+ NG WS P C ++ +C + NG +Q +Y A + C LG++
Sbjct: 430 TCMENG-WS---PTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTAD 485
Query: 2754 SAVRECLSSGL--WSESETRCLAGHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRL 2809
++ G WS T C+ C IP + +N + + ++ DT+ Y+C+ G+
Sbjct: 486 GETSGSITCGKDGWSAQPT-CIKS-CDIP-VFMNARTKNDFTWFKLNDTLDYECHDGYES 542
Query: 2810 -IGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY--GRTSGNGFNFNDVVTFSCNIGYL 2866
GS+ +N LP C C P ++ + + +V+ FSC G+
Sbjct: 543 NTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFT 602
Query: 2867 MQGPTKAQCQANRQWSHPPPMCK--VVNCSDPG--IPANSKRESKIEHGNFTYGTVVFYD 2922
+ GP QC + S P+CK V +C P + N K ++K E+G + VV Y
Sbjct: 603 IVGPNSVQCY-HFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYG---HSEVVEYY 658
Query: 2923 CNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN----AVLSGEKYTFGSTVH 2978
CNP + + G + + C +G+W LP CI+ + +P A LS Y +G +V
Sbjct: 659 CNPRFLMKGPNKIQCV-DGEWTT-LPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVE 716
Query: 2979 YSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG-DATGTCGDPGTP--GHGSRQESNFRTK 3035
++C+ +++G S TC ++G W+ P C D C + + F
Sbjct: 717 FNCSESFTMIGHRSITC-IHGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHN 774
Query: 3036 STVRYAC--DTGYILHGSEERTCLANGSWTGRQPECKAVQ---CGNPGTTANGKVFRIDG 3090
S +RY C G+I T NG W + C Q C P N
Sbjct: 775 SNIRYRCRGKEGWI------HTVCINGRWDP-EVNCSMAQIQLCPPPPQIPNSHNMT--- 824
Query: 3091 TTFS----SSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI-ISCGDP-----GIPA 3140
TT + V C E Y++ C +G W ++P C I C P G
Sbjct: 825 TTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRWQ-SIPLCVEKIPCSQPPQIEHGTIN 882
Query: 3141 NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS 3200
+ + Y G +SY C+ G+ ++ TC + G WS P C + C +PP+IS
Sbjct: 883 SSRSSQESYAHGTKLSYTCEGGF--RISEENETTCYM-GKWSSP-PQCEGLPCKSPPEIS 938
Query: 3201 NGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC-----GD 3253
+G + ++ +G ++Y C G+ + PA+ C+G WS P C+ C +
Sbjct: 939 HGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWS-HPPSCIKTDCLSLPSFE 996
Query: 3254 PGIPAQGKREGKSFIYQS--EVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3311
IP K++ +Y++ +V+++C + + G+S C + W+G P C TS
Sbjct: 997 NAIPMGEKKD----VYKAGEQVTYTCATYYKMDGASNVTC-INSRWTG-RPTC---RDTS 1047
Query: 3312 CENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 3369
C NP ++ + G V++ C+ + + G CL + W+ P+C
Sbjct: 1048 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWTE-PPQCKDS 1105
Query: 3370 S--CKQPETPAHANVVGMDLPSH--GYTLIYTCQPGFFLAGGTEHRVCRS 3415
+ C P + ++ L + ++ Y CQ + G + CR+
Sbjct: 1106 TGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQ-NLYQLEGNKRITCRN 1154
Score = 149 bits (375), Expect = 7e-35
Identities = 156/580 (26%), Positives = 239/580 (41%), Gaps = 70/580 (12%)
Query: 2887 MCKVVNCSDPGIPANSKRESKIEHGNF---TY--GTVVFYDCNPGYFLFGSSVLICQPNG 2941
+C +C++ +P +R ++I G++ TY GT Y C PGY G+ +++C+ G
Sbjct: 15 ICVAEDCNE--LPP--RRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KG 69
Query: 2942 QWD--KPLPECIMIDCGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSS-RTC 2995
+W PL +C CGHPG P + G + +G Y+C LLG+ + R C
Sbjct: 70 EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYREC 129
Query: 2996 QLNGHWSGSQPHCSGDATGTCGDPGTPGHGS------RQESNFRTKSTVRYACDTGYILH 3049
+G W+ P C C P +G + + VR+ C++GY +
Sbjct: 130 DTDG-WTNDIPICE---VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 3050 GSEERTCLANGSWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCMEGY 3105
G EE C +G W+ +P+C + C +P G+ + K+ + F Y C GY
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ----YKCNMGY 241
Query: 3106 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG----LRYGDDYVVGQNVSYMCQP 3161
S CT +G W LP+C SC +P IP NG LR + G ++Y C+
Sbjct: 242 EYSERGDAVCTESG-WR-PLPSCEEKSCDNPYIP-NGDYSPLRI--KHRTGDEITYQCRN 296
Query: 3162 GYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNF-------DWGFS 3214
G+ G+ + CT G W P C C P I +G L N G
Sbjct: 297 GFYPATRGNTAK-CTSTG-WIPA-PRCTLKPCDY-PDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 3215 ISYICSPGYEL---SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQ 3270
SY C +E S+ + C +G WS VP CL K C P + + G+ F+
Sbjct: 353 YSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLRK-CYFPYLENGYNQNHGRKFVQG 409
Query: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQ 3330
+ +C+ + L + T + + WS +P CI S + + + + +
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENGWS-PTPRCIRVKTCSKSSIDIENGFISESQYTYA 468
Query: 3331 VGSVVQFHCKKGHLLQGSTTR---TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDL 3387
+ ++ CK G++ T TC D WS QP CI SC P
Sbjct: 469 LKEKAKYQCKLGYVTADGETSGSITCGKD-GWSA-QPTCI-KSCDIPVFMNARTKNDFTW 525
Query: 3388 PSHGYTLIYTCQPGF-FLAGGTEHRVCRSDNTWTGKVPIC 3426
TL Y C G+ G T + N W+ +PIC
Sbjct: 526 FKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWS-DLPIC 564
Score = 144 bits (362), Expect = 2e-33
Identities = 201/774 (25%), Positives = 295/774 (38%), Gaps = 94/774 (12%)
Query: 2714 CQIISCGELPTPPN-----GNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2768
C C ELP N G+ G+ AI+ C G+ +G+ + C G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 2769 ET--RCLAGHCGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGS-SVRICQQDHN 2822
+C CG P G G + Y VY CN G++L+G + R C D
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTD-G 133
Query: 2823 WSGQLPSCVPVSCGHPGSPIYGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKAQCQ 2876
W+ +P C V C +P G+ + ++F V F CN GY ++G + C
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 2877 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKI---EHGNFTYGTVVFYDCNPGYFLFGSS 2933
+ WS P C ++C P + S KI E+ F Y CN GY
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ------YKCNMGYEYSERG 247
Query: 2934 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSC-TGKRSLLGQ 2990
+C +G W +PLP C C +P + PN S K+ G + Y C G
Sbjct: 248 DAVCTESG-W-RPLPSCEEKSCDNPYI-PNGDYSPLRIKHRTGDEITYQCRNGFYPATRG 304
Query: 2991 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFR-------TKSTVRYACD 3043
++ C G W + P C+ C P HG N R Y CD
Sbjct: 305 NTAKCTSTG-WIPA-PRCT---LKPCDYPDIK-HGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 3044 TGYILHGS---EERTCLANGSWTGRQP---ECKAVQCGNPGTTANGKVFRIDGTTFSSSV 3097
+ + C +G W+ P +C N +G+ F + G S+
Sbjct: 359 EHFETPSGSYWDHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRKF-VQG----KSI 412
Query: 3098 IYSCMEGYIL-SGPSVRQCTANGTWSGTLPNC-TIISCGDPGIPANGLRYGDD---YVVG 3152
+C GY L + C NG WS T P C + +C I + Y +
Sbjct: 413 DVACHPGYALPKAQTTVTCMENG-WSPT-PRCIRVKTCSKSSIDIENGFISESQYTYALK 470
Query: 3153 QNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG--TNF 3209
+ Y C+ GY T + S TC +G WS PTC + P N R + T F
Sbjct: 471 EKAKYQCKLGYVTADGETSGSITCGKDG-WS-AQPTC--IKSCDIPVFMNARTKNDFTWF 526
Query: 3210 DWGFSISYICSPGYEL---SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS 3266
++ Y C GYE S + C NG WS ++P C + C P I + K
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELPKIDVHLVPDRKK 584
Query: 3267 FIYQ--SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN 3324
Y+ + FSC F +VG ++ C G S P C E Q SC P +G+
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQ-SCGPPPELLNGNVK 642
Query: 3325 NTFGFQVG--SVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETP-AHAN 3381
+ G VV+++C L++G C+ D W+ + P CI + P
Sbjct: 643 EKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTTL-PVCIVEESTCGDIPELEHG 700
Query: 3382 VVGMDLPSHGY--TLIYTCQPGFFLAGGTEHR-VCRSDNTWTGKVPICEAGSKI 3432
+ P + Y ++ + C F + G HR + WT ++P C A K+
Sbjct: 701 WAQLSSPPYYYGDSVEFNCSESFTMIG---HRSITCIHGVWT-QLPQCVAIDKL 750
Score = 139 bits (351), Expect = 4e-32
Identities = 177/729 (24%), Positives = 282/729 (38%), Gaps = 96/729 (13%)
Query: 2547 QLNSVVRWACDRGFRLVGKS---SAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI 2603
+LN + + C G+ S S VC GY+ W + +P C C +PK +
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSIVC-----GYNGW-SDLPICYERECELPKIDVH--- 577
Query: 2604 LTTD-----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCV--VVTCPS 2656
L D Y VG + + C G+ + + C G + P C V +C
Sbjct: 578 LVPDRKKDQYKVGEVLKFSCKPGFTIVGPN--SVQCYHFGLSPD---LPICKEQVQSCGP 632
Query: 2657 INSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQI 2716
+ +G + Y + V + C+P + GP I+C+ +G W+ P C +
Sbjct: 633 PPELL--NGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT---TLPVCIV 686
Query: 2717 --ISCGELPTPPNG--NKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772
+CG++P +G YG + F C F ++G C+ G+W++ +C
Sbjct: 687 EESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-GVWTQLP-QC 744
Query: 2773 LA----GHCGIPELIVNGQVIG--ENYGYRDTVVYQCNPGFRLIGSSVRIC-----QQDH 2821
+A C LI+ + + + + + + Y+C I + +C +
Sbjct: 745 VAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHT---VCINGRWDPEV 801
Query: 2822 NWS-GQLPSCVPVSCGHPGSP-IYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR 2879
N S Q+ C P P P + T+ + + V+ C YL+Q + C+ R
Sbjct: 802 NCSMAQIQLCPPP----PQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGR 857
Query: 2880 QWSHPPPMCKVVNCSDPG-IPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQ 2938
W P + + CS P I + S+ ++ +GT + Y C G+ + + C
Sbjct: 858 -WQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 2939 PNGQWDKPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSCTGKRSLLGQSSRTCQ 2996
G+W P P+C + C P + V++ + Y +G V Y C + G + C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKC- 973
Query: 2997 LNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTC 3056
L WS D G +++ ++ V Y C T Y + G+ TC
Sbjct: 974 LGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDV-YKAGEQVTYTCATYYKMDGASNVTC 1032
Query: 3057 LANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSS--VIYSCMEGYILSGPSVRQ 3114
+ N WTGR P C+ C NP T N + + + S V Y C Y + G
Sbjct: 1033 I-NSRWTGR-PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVM 1090
Query: 3115 CTANGTWSGTLPNC--TIISCGDPGIPANGLRYG---DDYVVGQNVSYMCQPGYTMELNG 3169
C NG W+ P C + CG P NG Y +V Y CQ Y +E G
Sbjct: 1091 CL-NGNWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLE--G 1146
Query: 3170 SRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFD--W----------GFSISY 3217
++ TC NG WS C P IS +E N W G S+ +
Sbjct: 1147 NKRITCR-NGQWS------EPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEF 1199
Query: 3218 ICSPGYELS 3226
+C GY LS
Sbjct: 1200 VCKRGYRLS 1208
Score = 94.0 bits (232), Expect = 2e-18
Identities = 132/590 (22%), Positives = 222/590 (37%), Gaps = 109/590 (18%)
Query: 2351 QLRVCQPPPPVPNAEILTED-DEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAP 2409
Q++ C PPP + N + + +E+ +++ Y C P F + G + C GE +
Sbjct: 626 QVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTL---- 681
Query: 2410 PVCQV---LCPANELRLDSTGVILSPG--YPDS-----------------------YPNL 2441
PVC V C + SP Y DS + L
Sbjct: 682 PVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQL 741
Query: 2442 QMCAWSISVE--KGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNIT 2499
C ++ K N+ + E + +KEFD S + G +
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFD---------HNSNIRYRCRGKEGWIHTVC 792
Query: 2500 SNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQT----GGQLNSVVRWA 2555
NG +W + + ++ C P P+ + ++ T G+ SV+
Sbjct: 793 ING-----RWDPEVNCSMAQIQL------CPPPPQIPNSHNMTTTLNYRDGEKVSVL--- 838
Query: 2556 CDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC-QAISCGIPKAPTNGGILTT-----DYL 2609
C + + C+ W + +P C + I C P +G I ++ Y
Sbjct: 839 CQENYLIQEGEEITCKDG-----RWQS-IPLCVEKIPCSQPPQIEHGTINSSRSSQESYA 892
Query: 2610 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTC---PSINSFILEHGR 2666
GT+++Y C G+R+S + TT G WS+ P+C + C P I+ ++ H
Sbjct: 893 HGTKLSYTCEGGFRISEENETTCYM---GKWSS---PPQCEGLPCKSPPEISHGVVAH-- 944
Query: 2667 WRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPP 2726
Y+Y +V + C G+ GPA +CL WS P C C LP+
Sbjct: 945 ----MSDSYQYGEEVTYKCFEGFGIDGPAIAKCL-GEKWS---HPPSCIKTDCLSLPSFE 996
Query: 2727 NGNKIGTQTSY---GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELI 2783
N +G + G +TC + + G++ C++S W+ T C C P +
Sbjct: 997 NAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINS-RWTGRPT-CRDTSCVNPPTV 1054
Query: 2784 VNGQVIG---ENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS--CGHP 2838
N ++ Y + V YQC + + G +C + NW+ + P C + CG P
Sbjct: 1055 QNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQCKDSTGKCGPP 1112
Query: 2839 GSPIYGRTSG---NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2885
G + + + V + C Y ++G + C+ N QWS PP
Sbjct: 1113 PPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWSEPP 1161
Score = 53.5 bits (127), Expect = 4e-06
Identities = 81/384 (21%), Positives = 135/384 (35%), Gaps = 47/384 (12%)
Query: 2351 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2410
Q+++C PPP +PN+ +T + G+ + C + + +TC+ G + P
Sbjct: 807 QIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSI----P 862
Query: 2411 VCQVLCPANELRLDSTGVILS-----PGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQT 2465
+C P ++ G I S Y C + + T ++ + +
Sbjct: 863 LCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSS 922
Query: 2466 EKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVF------------LQWSADH 2513
+ + L P I V+ +S Y +T E F +WS
Sbjct: 923 PPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPP 982
Query: 2514 GNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKS 2573
K + +F + P + + G Q V + C +++ G S+ C S
Sbjct: 983 SCIKTDC-LSLPSFENAIPMGEKKD--VYKAGEQ----VTYTCATYYKMDGASNVTCINS 1035
Query: 2574 SYGYHAWDAPVPACQAISCGIPKAPTNGGILT---TDYLVGTRVTYFCNDGYRLSSKELT 2630
+ P C+ SC P N I++ + Y G RV Y C Y + E
Sbjct: 1036 RW------TGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDE-- 1087
Query: 2631 TAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYH 2690
V +G W+ + P+C T +++G S Y + V + C Y
Sbjct: 1088 -EVMCLNGNWT---EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQ 1143
Query: 2691 GLGPASIECLPNGTWSWRNERPYC 2714
G I C NG WS E P C
Sbjct: 1144 LEGNKRITC-RNGQWS---EPPKC 1163
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 3332 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP--ECIPHSCKQP-ETPAHA-NVVGMDL 3387
G+ + C+ G+ G+ C W + P +C C P +TP + G ++
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVCRKG-EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNV 103
Query: 3388 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
+G +YTC G+ L G +R C +D WT +PICE + V P
Sbjct: 104 FEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAP 152
Score = 45.8 bits (107), Expect = 8e-04
Identities = 156/833 (18%), Positives = 275/833 (33%), Gaps = 157/833 (18%)
Query: 1496 NGTRNGDGRE--PGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPP-VCIAPCG-G 1550
NG GR+ G ++ C PGY L + + +TC+ EN W P+P + + C
Sbjct: 396 NGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCM--ENG--WSPTPRCIRVKTCSKS 451
Query: 1551 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1610
++ +GFI + + + A Y L +++ DG S
Sbjct: 452 SIDIENGFISESQYTY----------ALKEKAKYQCKLGYVTA------------DGETS 489
Query: 1611 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNG 1670
S G S P I+S + + R+ ++
Sbjct: 490 GSITCGKDGWSAQPTCIKSCDIPVFMNARTKNDFTW------------------------ 525
Query: 1671 TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSE 1730
+KL T+ Y C GY ST I+ G GW+ LP C+
Sbjct: 526 ------FKLNDTLDYECHDGYESNTGSTTGSIVC--GYNGWSD-LPICYER--ECELPKI 574
Query: 1731 GTVLSPNYPKN-YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLS 1789
L P+ K+ Y VG +S V + L + + Q
Sbjct: 575 DVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPP 634
Query: 1790 SLSGSHSGESLPLSSGNQITI------RFTSVGPITAKGFHFVYQAVPR--TSSTQCSSV 1841
L + E G+ + RF GP + + +P + C +
Sbjct: 635 ELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDI 694
Query: 1842 PEPRFG--RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPC 1899
PE G + + G SV F+C+ + + G +I C W LP C+
Sbjct: 695 PELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-----GVWTQ-LPQCVAID 748
Query: 1900 GGILTKRKGTILSPGY---PEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1956
K I+ + + +D+N N ++ EG + + WD
Sbjct: 749 KLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEG-----WIHTVCINGRWDP---- 799
Query: 1957 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAA----------------GF 2000
+ N P + NS + LN++ VS
Sbjct: 800 ---EVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDG 856
Query: 2001 HLEYTAIGLDSCPEPQTP-------SSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCM 2053
+ + ++ P Q P +S + Y G +S+ C+ G+ + + TC
Sbjct: 857 RWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 2054 PGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQF 2113
G +W+ P C GV+ Y + T GFG+
Sbjct: 917 MG---KWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEV----TYKCFEGFGIDGPA 969
Query: 2114 VN--FSTETIHDYLEVRSG-----SSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2166
+ + H +++ S E + +G + + T+ + Y+ D +
Sbjct: 970 IAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKK--DVYKAGEQVTYTCATYYKMDGA 1027
Query: 2167 QNKQGFHIVYQAYQL---QSCPDPRPFRNGFVIGND---FTVGQTISFECFPGYTLIGNS 2220
N + + SC +P +N +++ + G+ + ++C Y + G+
Sbjct: 1028 SNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDE 1087
Query: 2221 ALTCLHGVSRNWNHPLPRCE---ALCG-------GNITAMNGTIYSPGYPDEY 2263
+ CL+G NW P P+C+ CG G+IT+ ++Y+P EY
Sbjct: 1088 EVMCLNG---NWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEY 1136
Score = 42.7 bits (99), Expect = 0.007
Identities = 64/306 (20%), Positives = 108/306 (35%), Gaps = 37/306 (12%)
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC-Q 2413
C+ PP + + + D ++ G+ + Y+C GF + G AI C LGE+ PP C +
Sbjct: 931 CKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKC-LGEKW---SHPPSCIK 986
Query: 2414 VLCPA-----NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE 2468
C + N + + + G +Y CA ++ N+T +
Sbjct: 987 TDCLSLPSFENAIPMGEKKDVYKAGEQVTY----TCATYYKMDGASNVTCINSRWTGRPT 1042
Query: 2469 FDVLQVYDGPNIQSPVLISLS-GDYSSAFNITSNGHEVFLQWSAD-----HGNNKKGFRI 2522
+ P +Q+ ++S Y S + + + + +GN + +
Sbjct: 1043 CRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQC 1102
Query: 2523 RYIAFYCSTPESPPHGYIIS--QTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAW 2580
+ C P +G I S + S V + C ++L G CR W
Sbjct: 1103 KDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQ-----W 1157
Query: 2581 DAPVPACQAISCGIPKAPTNGGILTTDYL--------VGTRVTYFCNDGYRLSSKELTTA 2632
P P C C I + + + G V + C GYRLSS+ T
Sbjct: 1158 SEP-PKC-LHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLR 1215
Query: 2633 VCQSDG 2638
DG
Sbjct: 1216 TTCWDG 1221
Score = 42.4 bits (98), Expect = 0.009
Identities = 44/156 (28%), Positives = 58/156 (37%), Gaps = 14/156 (8%)
Query: 134 QSSSCGNPGVPPKGVLY---GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
Q CG+PG P G G F+ G K Y+C GY L G +T W
Sbjct: 81 QKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTN 136
Query: 191 PVPICRAEDACGGTMRGSSGIISSPSFPN-EYHNNAD----CTWTIVAEPGDTISLIFTD 245
+PIC T + I+SS P+ EYH C E + +
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 246 FQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKN 281
F +EK +EI P I +G I II +N
Sbjct: 197 FWSKEKPKCVEISCKSPDVI--NGSPISQKIIYKEN 230
Score = 41.6 bits (96), Expect = 0.015
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 2355 CQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE 2401
C PP N EILT D + G Y+C PG+ +GN I+ CR GE
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGE 70
Score = 39.7 bits (91), Expect = 0.056
Identities = 51/253 (20%), Positives = 98/253 (38%), Gaps = 37/253 (14%)
Query: 2012 CPEPQTPSSGI--KIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2069
C P S G+ + D Y G+ V+++C +G+ + G + C+ +W++P P C+
Sbjct: 931 CKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLG---EKWSHP-PSCIK 986
Query: 2070 QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINL--PIGFGVHLQFVNF---STETIHDY 2124
++ F I Y + T+T + ++ +N T D
Sbjct: 987 TDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDT 1046
Query: 2125 LEVRSGSSETSTVIGRL-----SGPQI------PSSLFSTTHETSLYFHSDYSQNKQGFH 2173
V + + + ++ R SG ++ P +F E + + ++++ Q
Sbjct: 1047 SCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD--EEVMCLNGNWTEPPQCKD 1104
Query: 2174 IVYQAYQLQSCPDPRPFRNGFVIGNDFTV---GQTISFECFPGYTLIGNSALTCLHGVSR 2230
C P P NG + +V ++ ++C Y L GN +TC +G
Sbjct: 1105 ------STGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNG--- 1155
Query: 2231 NWNHPLPRCEALC 2243
W+ P P+C C
Sbjct: 1156 QWSEP-PKCLHPC 1167
Score = 39.3 bits (90), Expect = 0.073
Identities = 54/246 (21%), Positives = 95/246 (38%), Gaps = 46/246 (18%)
Query: 2197 GNDFTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRC---EALCGGNITAMNG 2252
G F G++I C PGY L + +TC+ W+ P PRC + +I NG
Sbjct: 403 GRKFVQGKSIDVACHPGYALPKAQTTVTCMEN---GWS-PTPRCIRVKTCSKSSIDIENG 458
Query: 2253 TIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQ 2312
I Y + ++ + + E DG I
Sbjct: 459 FISESQYT----------YALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKS 508
Query: 2313 ------FSGNTALESVYSTSNQIL-IKFHSDF-----TTSGFFVLSYHAYQ-LRVC-QPP 2358
+ T + + N L + H + +T+G V Y+ + L +C +
Sbjct: 509 CDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERE 568
Query: 2359 PPVPNAEI-LTED---DEFEIGDIIRYQCLPGFTLVG-NAILTCRLG---------ERLQ 2404
+P ++ L D D++++G+++++ C PGFT+VG N++ G E++Q
Sbjct: 569 CELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQ 628
Query: 2405 MDGAPP 2410
G PP
Sbjct: 629 SCGPPP 634
Score = 38.5 bits (88), Expect = 0.12
Identities = 57/273 (20%), Positives = 97/273 (35%), Gaps = 28/273 (10%)
Query: 1791 LSGSHSGESLPLSSGNQITIR----FTSVGPITA---KGFHFVYQAVPRTSSTQCSSVPE 1843
L+GS S ++ P G Q + + S+G + KG + + C +
Sbjct: 33 LTGSWSDQTYP--EGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGD 90
Query: 1844 PRFGRRI---GNEFAVGSSVLFDCNPGYILHGSIAIR-CETVPNSLAQWNDSLPTC-IVP 1898
FG GN F G ++ CN GY L G I R C+T W + +P C +V
Sbjct: 91 TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT-----DGWTNDIPICEVVK 145
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1958
C + G I+S + + + G I+ ++ + S +
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Query: 1959 GDNNAPRLGSYSGTTIPHLLNSTSNNLY---LNFQSDISVSAAGFHLEYTAIGLDSCPEP 2015
+ + +G+ I + N + N + S E L SC E
Sbjct: 206 VEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEK 265
Query: 2016 QTPSSGIKIGD------RYMVGDVVSFQCDQGY 2042
+ I GD ++ GD +++QC G+
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGF 298
Score = 38.1 bits (87), Expect = 0.16
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)
Query: 617 KEIEKESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 673
++ +K CG PG +G + G+ F + C G++L+GE + + + W+ +
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTND 137
Query: 674 IPIC-IFPCLSNFTAP-----MGTVLSPDYPEGYG 702
IPIC + CL TAP + + + PD +G
Sbjct: 138 IPICEVVKCLP-VTAPENGKIVSSAMEPDREYHFG 171
Score = 38.1 bits (87), Expect = 0.16
Identities = 64/286 (22%), Positives = 105/286 (36%), Gaps = 54/286 (18%)
Query: 965 VNTYSCLDPGIPVHG-----RRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHP 1019
V C P HG R ++ G+ +S++C+ G+R+S E C W S
Sbjct: 865 VEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSP- 923
Query: 1020 LPTCDAL-CGGDVRGPSGTI--LSPGYPEFYPNSLNCTWTVDVTHGKGVQFN-FHTFHLE 1075
P C+ L C G + +S Y +G+ V + F F ++
Sbjct: 924 -PQCEGLPCKSPPEISHGVVAHMSDSY----------------QYGEEVTYKCFEGFGID 966
Query: 1076 DHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGN----FRAQLRFISDFSISYE--- 1128
+ E S + LP NA G ++A + + Y+
Sbjct: 967 GPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDG 1026
Query: 1129 GFNITF--SEYNLEP------CEDPGIPQYG---SRIGFNFGIGDTLTFSCSSGYRLEGT 1177
N+T S + P C +P Q SR + G+ + + C S Y + G
Sbjct: 1027 ASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD 1086
Query: 1178 SEIICLGGGRRVWSAPLPRC---VAECGASATNNEGILLSPNYPLN 1220
E++CL G W+ P P+C +CG + G + S +PL+
Sbjct: 1087 EEVMCLNGN---WTEP-PQCKDSTGKCGPPPPIDNGDITS--FPLS 1126
Score = 37.7 bits (86), Expect = 0.21
Identities = 82/379 (21%), Positives = 133/379 (35%), Gaps = 100/379 (26%)
Query: 1044 PEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLA-RLTGSDLP 1102
P PNS N T T++ G+ V +L + + + + PL P
Sbjct: 814 PPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQP 873
Query: 1103 PTINAGLYGNFRA-QLRFISDFSISYE---GFNITFSEYNLE----------------PC 1142
P I G + R+ Q + +SY GF I SE N PC
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRI--SEENETTCYMGKWSSPPQCEGLPC 931
Query: 1143 EDPGIPQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE 1200
+ P +G + + ++ G+ +T+ C G+ ++G + CLG WS P P C+
Sbjct: 932 KSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLG---EKWSHP-PSCIKT 987
Query: 1201 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK 1260
S + E + P+ + + +Y +AG+ + + T++ DG
Sbjct: 988 DCLSLPSFENAI-----PMGEKKD---VY----KAGEQVTYTCATYYK--------MDGA 1027
Query: 1261 DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP 1320
T + +TG T TS C +P
Sbjct: 1028 SNVTCINSRWTGRP----TCRDTS-----------------------------CVNPPTV 1054
Query: 1321 QFGYKISDQ--GHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRF 1378
Q Y +S Q + +G + Y C Y + G + C+ G W P P C
Sbjct: 1055 QNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGN---WTEP-PQC-------- 1102
Query: 1379 KGESSGRILSPGYPFPYDN 1397
+S+G+ G P P DN
Sbjct: 1103 -KDSTGKC---GPPPPIDN 1117
Score = 37.4 bits (85), Expect = 0.28
Identities = 13/39 (33%), Positives = 22/39 (56%)
Query: 985 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
++ G V F C+SGY++ +E + C + +WS P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Score = 37.4 bits (85), Expect = 0.28
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 1158 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
+ G + F C+SGY++EG E+ C G WS P+CV
Sbjct: 168 YHFGQAVRFVCNSGYKIEGDEEMHCSDDG--FWSKEKPKCV 206
Score = 36.6 bits (83), Expect = 0.47
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 5/43 (11%)
Query: 1506 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
P +V +QC Y+L+G +RITC + W PP C+ PC
Sbjct: 1130 PASSVEYQCQNLYQLEGNKRITCRNGQ----WS-EPPKCLHPC 1167
Score = 35.8 bits (81), Expect = 0.80
Identities = 52/234 (22%), Positives = 92/234 (39%), Gaps = 30/234 (12%)
Query: 1327 SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE-CGGRFKGESSGR 1385
SDQ + G+ IY C PGY G+ ++ C GE A + PL C CG
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALN-PLRKCQKRPCGHPGDTPFGTF 96
Query: 1386 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD-------GPPEN 1438
L+ G F Y ++ ++ + + + DT+ + + + + PEN
Sbjct: 97 TLTGGNVFEY--GVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPEN 154
Query: 1439 DMLLKEISGSLIPEGIHSTLNIV--------TIQFDTDFYISKSGF-AIQFSSSVATACR 1489
K +S ++ P+ + V I+ D + + S GF + + V +C+
Sbjct: 155 G---KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK 211
Query: 1490 DPGVPMNGTRNGDG--REPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1541
P V +NG+ + + ++C+ GYE C + W+P P
Sbjct: 212 SPDV-INGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG----WRPLP 260
Score = 35.4 bits (80), Expect = 1.0
Identities = 83/422 (19%), Positives = 147/422 (34%), Gaps = 69/422 (16%)
Query: 1161 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLN 1220
GD++ F+CS + + G I C+ G VW+ LP+CVA + +++ + N
Sbjct: 712 GDSVEFNCSESFTMIGHRSITCIHG---VWT-QLPQCVAIDKLKKCKSSNLIILEEHLKN 767
Query: 1221 ---YENNHECIYSIQVQAG------------KGINISARTFHLAQGDVLKIYDGKDKTTH 1265
+++N Y + + G +N S L +I + + TT
Sbjct: 768 KKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPP-QIPNSHNMTTT 826
Query: 1266 LLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFG-- 1323
L +++ N L ++ + D +Q + E C P + G
Sbjct: 827 L----NYRDGEKVSVLCQENYL-IQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTI 881
Query: 1324 --YKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGE 1381
+ S + + G+ + Y C G+ + + C G+ W P P C
Sbjct: 882 NSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGK---WSSP-PQCEGLPCKSPPEI 937
Query: 1382 SSGRI--LSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP--- 1436
S G + +S Y + + +C +D I + W PP
Sbjct: 938 SHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKC------------LGEKWSHPPSCI 985
Query: 1437 ENDMLLKEISGSLIPEG----IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA------- 1485
+ D L + IP G ++ VT T + + + +S
Sbjct: 986 KTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRD 1045
Query: 1486 TACRDPGVPMNG---TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPP 1542
T+C +P N +R G+ V +QC YE+ G+E + C+ W PP
Sbjct: 1046 TSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGN----W-TEPP 1100
Query: 1543 VC 1544
C
Sbjct: 1101 QC 1102
Score = 35.0 bits (79), Expect = 1.4
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 9/64 (14%)
Query: 1488 CRDPGVPMNGTRNGDGREP------GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1541
C P NG EP G V F C+ GY+++G+E + C + FW
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC---SDDGFWSKEK 202
Query: 1542 PVCI 1545
P C+
Sbjct: 203 PKCV 206
Score = 34.7 bits (78), Expect = 1.8
Identities = 55/256 (21%), Positives = 98/256 (38%), Gaps = 58/256 (22%)
Query: 453 ENG--KRIGSDFSLGSTVQFSCDEDYVLQGAKS-ITCQRIAEVFAAWSDHRPVCKVKTCG 509
ENG + G F G ++ +C Y L A++ +TC WS +VKTC
Sbjct: 395 ENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCME-----NGWSPTPRCIRVKTCS 449
Query: 510 -SNLQGPSGTFTSPNFPFQYDSNA--QCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
S++ +G + + + A QC ++ + D E ++T G
Sbjct: 450 KSSIDIENGFISESQYTYALKEKAKYQC-------------KLGYVTADGETS-GSITCG 495
Query: 567 DGGEVGDPRTVLQVLTGSFVPDLIVSMSSQM-----WLHLQ--------------TDESV 607
G P + D+ V M+++ W L T +
Sbjct: 496 KDGWSAQPTCIKSC-------DIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTT 548
Query: 608 GSVGFKVN-YKEIE---KESCGDPGTPLYGI--REGDGFSNRDVLRFECQFGFELIGEKS 661
GS+ N + ++ + C P ++ + R+ D + +VL+F C+ GF ++G S
Sbjct: 549 GSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNS 608
Query: 662 IVCQENNQWSANIPIC 677
+ C S ++PIC
Sbjct: 609 VQCYHFG-LSPDLPIC 623
Score = 34.3 bits (77), Expect = 2.3
Identities = 58/272 (21%), Positives = 94/272 (34%), Gaps = 50/272 (18%)
Query: 1830 VPRTSSTQCSSVPEPRFGRRIGN------EFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1883
+P +C V P G+ + + E+ G +V F CN GY + G + C +
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC----S 193
Query: 1884 SLAQWNDSLPTCI-VPCGGILTKRKGTILSPGYPEP----YDNNLNCVWKITVPEGAGIQ 1938
W+ P C+ + C K + G P Y N +K + G
Sbjct: 194 DDGFWSKEKPKCVEISC-------KSPDVINGSPISQKIIYKENERFQYKCNM--GYEYS 244
Query: 1939 VQVVSFATEHNWDSLDFYDGGDNNAPRL--GSYSGTTIPHLLNSTSNNLYLNFQSDISVS 1996
+ + TE W L + + P + G YS I H T + + ++ +
Sbjct: 245 ERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKH---RTGDEITYQCRNGFYPA 301
Query: 1997 AAGFHLEYTAIG--------LDSCPEPQTPSSGIKIGDR------YMVGDVVSFQCDQGY 2042
G + T+ G L C P G+ + VG S+ CD+ +
Sbjct: 302 TRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHF 361
Query: 2043 SLQGHS---HITCMPGPVRRWNYPIPICLAQC 2071
S HI C W+ +P CL +C
Sbjct: 362 ETPSGSYWDHIHCTQD---GWSPAVP-CLRKC 389
Score = 33.5 bits (75), Expect = 4.0
Identities = 99/480 (20%), Positives = 170/480 (35%), Gaps = 101/480 (21%)
Query: 794 CPDPGIPINARRFGD--NFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
CP P N+ N++ G +SV+C+E ++ +G E ITC DG+ W IP C
Sbjct: 811 CPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE-ITC--KDGR--WQS-IPLC 864
Query: 852 --GAPCGGHFSAPSGVILSP-----GWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTEL 904
PC G I S + K S CE + ++ +
Sbjct: 865 VEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPP 924
Query: 905 NYDVLEVHDGPNL----LSPLLGSYN-GTQVPQFLFSSSNFIYLLFTTDNSRSNN--GFK 957
+ L P + ++ + SY G +V F F D G K
Sbjct: 925 QCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEG-------FGIDGPAIAKCLGEK 977
Query: 958 IHYESVTVNTYSCL-----DPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 1012
+ + T CL + IP+ ++ + G V+++C + Y++ + C
Sbjct: 978 WSHPPSCIKT-DCLSLPSFENAIPMGEKK--DVYKAGEQVTYTCATYYKMDGASNVTCIN 1034
Query: 1013 NHWWSHPLPTC-DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHT 1071
+ W P TC D C + I+S + YP+ G+ V++ +
Sbjct: 1035 SRWTGRP--TCRDTSCVNPPTVQNAYIVSRQMSK-YPS------------GERVRYQCRS 1079
Query: 1072 FHLEDHHDYLLITENGSFTQP--LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYE 1128
+ E D ++ NG++T+P TG PP I+ G I+ F +S
Sbjct: 1080 PY-EMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNG----------DITSFPLSV- 1127
Query: 1129 GFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR 1188
+ ++ + C + Y+LEG I C G
Sbjct: 1128 -----------------------------YAPASSVEYQCQNLYQLEGNKRITCRNG--- 1155
Query: 1189 VWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL 1248
WS P P+C+ C S E ++ + + S++ +G +S+R+ L
Sbjct: 1156 QWSEP-PKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTL 1214
Score = 33.5 bits (75), Expect = 4.0
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 14/65 (21%)
Query: 646 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 705
+ ++CQ ++L G K I C+ N QWS P C+ PC V+S + E Y N+
Sbjct: 1134 VEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPC----------VISREIMENY--NI 1179
Query: 706 NCIWT 710
WT
Sbjct: 1180 ALRWT 1184
Score = 32.7 bits (73), Expect = 6.8
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%)
Query: 446 CPDPGEPENG--KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C D E E+G + + G +V+F+C E + + G +SITC + W+ P C
Sbjct: 691 CGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-----IHGVWT-QLPQC 744
Query: 504 ----KVKTCGSN 511
K+K C S+
Sbjct: 745 VAIDKLKKCKSS 756
Score = 32.3 bits (72), Expect = 8.9
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Query: 1676 DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
+Y G V + C++GY ++G + C DDG W++ P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHC--SDDG--FWSKEKPKC 205
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 176 bits (447), Expect = 3e-43
Identities = 138/510 (27%), Positives = 213/510 (41%), Gaps = 49/510 (9%)
Query: 2591 SCGIPK-----APTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2645
+CG P AP + + T + GT + Y C GY + S T C SDG W +
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGY-VRSHSTQTLTCNSDGEWVYNTF 107
Query: 2646 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIEC-LPNGT 2704
C+ C L +G+ I + + +++ FSC G+ +G + C + +
Sbjct: 108 ---CIYKRCRHPGE--LRNGQVEIK--TDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRG 160
Query: 2705 WSWRNERPYCQIISCGELPTPPNGNKIGTQT--SYGSTAIFTCDLGFMLVGSAVRECL-- 2760
W + P C+I+ C P NG G + +YG + ++CD F L+G A C
Sbjct: 161 VGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVE 220
Query: 2761 --SSGLWSESETRCLAGHCGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGSSVR 2815
+ G+W S C C P+ + +G+++ G Y Y+DT+V++C GF L GSSV
Sbjct: 221 NETIGVWRPSPPTCEKITCRKPD-VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVI 279
Query: 2816 ICQQDHNWSGQLPSCVPVSC------GHPGSPIYGR-TSGNGFNFNDVVTFSCNIGY--L 2866
C D W+ P+C P SC H Y R T + + V+ + C+ GY
Sbjct: 280 HCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPT 339
Query: 2867 MQGPTKAQCQANRQWSHPPPMCKVVNCSDP----GIPANSKRESKIEHGNFTYGTVVFYD 2922
PT CQ N +W+ P C+ + C +P G ++ H + YG + +
Sbjct: 340 TDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFS 398
Query: 2923 CNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYT-FGSTVHYSC 2981
C+ ICQ +G W P C I P + Y+ F + Y C
Sbjct: 399 CHE----TSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYEC 454
Query: 2982 TGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG-TPGHGSRQESNFRTKSTVRY 3040
L+GQ+ +C + HWS P C C P G S + + V
Sbjct: 455 DKGYILVGQAKLSCSYS-HWSAPAPQCK----ALCRKPELVNGRLSVDKDQYVEPENVTI 509
Query: 3041 ACDTGYILHGSEERTCLANGSWTGRQPECK 3070
CD+GY + G + TC N +W P+C+
Sbjct: 510 QCDSGYGVVGPQSITCSGNRTWYPEVPKCE 539
Score = 161 bits (408), Expect = 1e-38
Identities = 140/518 (27%), Positives = 221/518 (42%), Gaps = 54/518 (10%)
Query: 2892 NCSDPG-IPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSS-VLICQPNGQWDKPLPE 2949
NC P + + + + F GT + Y C PGY S+ L C +G+W
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-F 107
Query: 2950 CIMIDCGHPGVPPNAVLSGEK-YTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQ 3005
CI C HPG N + + +FGS + +SC+ L+G ++ C++ WS
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 3006 PHCSGDATGTCGDPGTPGHG--SRQESNFRTKSTVRYACDTGYILHGSEERTCLAN---- 3059
P C C P +G S +E+ + +V Y+CD + L G +C
Sbjct: 168 PQCE---IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI 224
Query: 3060 GSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTA 3117
G W P C+ + C P + +G++ G ++ ++++ C +G++L G SV C A
Sbjct: 225 GVWRPSPPTCEKITCRKPDVS-HGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDA 283
Query: 3118 NGTWSGTLPNCTIISCGD-PGIP-ANGLRY-----GDDYVVGQNVSYMCQPGYTMELNGS 3170
+ W+ + P C SC + P IP A+ Y D YVVG + Y C PGY +
Sbjct: 284 DSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEP 343
Query: 3171 RIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN---------FDWGFSISYICSP 3221
C N W+ C A+ CP P+++NG + + +G IS+ C
Sbjct: 344 TTVICQKNLRWTPYQ-GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSC-- 399
Query: 3222 GYELS-FPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG--KREGKSFIYQSEVSFSCN 3278
+E S F A+ C G+GTWS P C C P A G K+ ++ E+ + C+
Sbjct: 400 -HETSRFSAI--CQGDGTWSPRTPSC-GDICNFPPKIAHGHYKQSSSYSFFKEEIIYECD 455
Query: 3279 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3338
+ILVG + C + WS +P C + C P + + + V
Sbjct: 456 KGYILVGQAKLSC-SYSHWSAPAPQC----KALCRKPELVNGRLSVDKDQYVEPENVTIQ 510
Query: 3339 CKKGHLLQGSTTRTCLPDLTWSGIQPEC---IPHSCKQ 3373
C G+ + G + TC + TW P+C P C+Q
Sbjct: 511 CDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQ 548
Score = 156 bits (394), Expect = 4e-37
Identities = 141/518 (27%), Positives = 214/518 (41%), Gaps = 45/518 (8%)
Query: 2718 SCGELPT-----PPNGNKIGTQTSYGSTAIFTCDLGFMLVGSA-VRECLSSGLWSESETR 2771
+CG PT P + T+ G+T +TC G++ S C S G W + T
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYN-TF 107
Query: 2772 CLAGHCGIPELIVNGQV-IGENYGYRDTVVYQCNPGFRLIGSSVRICQ-QDHN--WSGQL 2827
C+ C P + NGQV I + + + + C+ GF LIGS+ C+ QD WS L
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 2828 PSCVPVSCGHPGSPIYGRTSG--NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ----W 2881
P C V C P GR SG N + + VT+SC+ + + G C + W
Sbjct: 168 PQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 2882 SHPPPMCKVVNCSDPGIPANSKRESKIEHGN-FTYGTVVFYDCNPGYFLFGSSVLICQPN 2940
PP C+ + C P + S E G + Y + + C G+ L GSSV+ C +
Sbjct: 228 RPSPPTCEKITCRKPDV---SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDAD 284
Query: 2941 GQWDKPLPECIMIDCGH-PGVPPNA------VLSGEKYTFGSTVHYSC-TGKRSLLGQSS 2992
+W+ P C C + P +P + + Y G+ + Y C G + + +
Sbjct: 285 SKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPT 344
Query: 2993 RT-CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKS--TVRYACDTGYILH 3049
CQ N W+ Q G C +P Q R + Y + + H
Sbjct: 345 TVICQKNLRWTPYQ----GCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCH 400
Query: 3050 GSEERT--CLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF-SSSVIYSCMEGYI 3106
+ + C +G+W+ R P C + C P A+G + +F +IY C +GYI
Sbjct: 401 ETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYI 459
Query: 3107 LSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYTM 3165
L G + C+ + WS P C + C P + L D YV +NV+ C GY +
Sbjct: 460 LVGQAKLSCSYSH-WSAPAPQCKAL-CRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGV 517
Query: 3166 ELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGR 3203
G + TC+ N TW +P C T Q+ G+
Sbjct: 518 V--GPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGK 553
Score = 144 bits (362), Expect = 2e-33
Identities = 130/512 (25%), Positives = 209/512 (40%), Gaps = 53/512 (10%)
Query: 2951 IMIDCGHP-----GVPPNAVLSGEKYTFGSTVHYSCT-GKRSLLGQSSRTCQLNGHWSGS 3004
++ +CG P P + L+ ++ G+T+ Y+C G + TC +G W +
Sbjct: 46 VLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYN 105
Query: 3005 QPHCSGDATGTCGDPGTPGHGSRQ-ESNFRTKSTVRYACDTGYILHGSEERTCLANG--- 3060
C C PG +G + +++ S + ++C G+ L GS C
Sbjct: 106 T-FC---IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV 161
Query: 3061 SWTGRQPECKAVQCGNPGTTANGKVFRIDGT-TFSSSVIYSCMEGYILSGPSVRQCTAN- 3118
W+ P+C+ V+C P NG+ + + SV YSC + L G + CT
Sbjct: 162 GWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVEN 221
Query: 3119 ---GTWSGTLPNCTIISCGDPGIPANGL--RYGDDYVVGQNVSYMCQPGYTMELNGSRIR 3173
G W + P C I+C P + + +G Y + + CQ G+ L GS +
Sbjct: 222 ETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFV--LRGSSVI 279
Query: 3174 TCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG----TNFDW---GFSISYICSPGYELS 3226
C + W+ P C +C P I + E T D G + Y C PGY+ +
Sbjct: 280 HCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPT 339
Query: 3227 F--PAVLTCVGNGTWS---GEVPQCLPKFCGDPGIPAQGKREGKS----FIYQSEVSFSC 3277
P + C N W+ G C P+ + G Q ++ + + Y E+SFSC
Sbjct: 340 TDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSC 399
Query: 3278 NFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFGFQVGSVV 3335
+ + ICQ DGTWS +P C + C P HG Q++++ F ++
Sbjct: 400 HE----TSRFSAICQGDGTWSPRTPSCGD----ICNFPPKIAHGHYKQSSSYSFFKEEII 451
Query: 3336 QFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLI 3395
+ C KG++L G +C WS P+C C++PE V D +
Sbjct: 452 -YECDKGYILVGQAKLSCSYS-HWSAPAPQC-KALCRKPELVNGRLSVDKDQYVEPENVT 508
Query: 3396 YTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3427
C G+ + G + C + TW +VP CE
Sbjct: 509 IQCDSGYGVVG-PQSITCSGNRTWYPEVPKCE 539
Score = 132 bits (331), Expect = 8e-30
Identities = 111/446 (24%), Positives = 178/446 (39%), Gaps = 44/446 (9%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
C P +G + +T S + ++C GF L+G +++ C G W P+P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV-GWSHPLPQCE 171
Query: 2589 AISCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSD--GTWSNHN 2644
+ C P NG + Y G VTY C+ + L + +++ G W
Sbjct: 172 IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW--RP 229
Query: 2645 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2704
P C +TC + + HG G Y YK +VF C G+ G + I C +
Sbjct: 230 SPPTCEKITCRKPD---VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC--DAD 284
Query: 2705 WSWRNERPYCQIISCGELPTPPNGN-----KIGTQTSY--GSTAIFTCDLGFMLVGSAVR 2757
W P C+ SC LP P+ + + + Y G+ + C G+
Sbjct: 285 SKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPT 344
Query: 2758 E--CLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN---------YGYRDTVVYQCNPG 2806
C + W+ + C A C P+L NG++ Y Y D + + C+
Sbjct: 345 TVICQKNLRWTPYQ-GCEALCCPEPKL-NNGEITQHRKSRPANHCVYFYGDEISFSCHET 402
Query: 2807 FRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG--RTSGNGFNFNDVVTFSCNIG 2864
R ICQ D WS + PSC + C P +G + S + F + + + C+ G
Sbjct: 403 SRFSA----ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKG 457
Query: 2865 YLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2924
Y++ G K C + WS P P CK + C P + N + ++ + V C+
Sbjct: 458 YILVGQAKLSCSYS-HWSAPAPQCKAL-CRKPEL-VNGR--LSVDKDQYVEPENVTIQCD 512
Query: 2925 PGYFLFGSSVLICQPNGQWDKPLPEC 2950
GY + G + C N W +P+C
Sbjct: 513 SGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 100 bits (248), Expect = 3e-20
Identities = 94/362 (25%), Positives = 144/362 (39%), Gaps = 45/362 (12%)
Query: 2552 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILT---TDY 2608
V ++CD F L+G +S C + W P C+ I+C P ++G +++ Y
Sbjct: 199 VTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDV-SHGEMVSGFGPIY 257
Query: 2609 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRW- 2667
+ + C G+ L + C +D W + P C +C IN + H W
Sbjct: 258 NYKDTIVFKCQKGFVLRGSSVIH--CDADSKW--NPSPPACEPNSC--INLPDIPHASWE 311
Query: 2668 ---RIVNGSHYEYKTKVVFSCDPGYHGL--GPASIECLPNGTWSWRNERPY--CQIISCG 2720
R Y T + + C PGY P ++ C N W+ PY C+ + C
Sbjct: 312 TYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-----PYQGCEALCCP 366
Query: 2721 ELPTPPNGNKIGTQTS---------YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR 2771
E P NG + S YG F+C SA+ C G WS
Sbjct: 367 E-PKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF--SAI--CQGDGTWSPRTPS 421
Query: 2772 CLAGHCGIPELIVNGQV-IGENYG-YRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2829
C C P I +G +Y +++ ++Y+C+ G+ L+G + C H WS P
Sbjct: 422 C-GDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSH-WSAPAPQ 479
Query: 2830 CVPVSCGHPGSPIYGRTSGNGFNF--NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPM 2887
C + C P + GR S + + + VT C+ GY + GP C NR W P
Sbjct: 480 CKAL-CRKP-ELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPK 537
Query: 2888 CK 2889
C+
Sbjct: 538 CE 539
Score = 98.2 bits (243), Expect = 1e-19
Identities = 77/261 (29%), Positives = 113/261 (43%), Gaps = 23/261 (8%)
Query: 3193 CPTPPQISNGR-----LEGTNFDWGFSISYICSPGYELSFPA-VLTCVGNGTWSGEVPQC 3246
C PP +S L T F G ++ Y C PGY S LTC +G W C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FC 108
Query: 3247 LPKFCGDPGIPAQGKREGKSFI-YQSEVSFSCNFPFILVGSSTRICQADGT---WSGSSP 3302
+ K C PG G+ E K+ + + S++ FSC+ F L+GS+T C+ WS P
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 3303 HCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDL---- 3357
C C+ P R+G + F G V + C L G + +C +
Sbjct: 169 QC---EIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIG 225
Query: 3358 TWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGY--TLIYTCQPGFFLAGGTEHRVCRS 3415
W P C +C++P+ +H +V P + Y T+++ CQ GF L G + C +
Sbjct: 226 VWRPSPPTCEKITCRKPDV-SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIH-CDA 283
Query: 3416 DNTWTGKVPICEAGSKILVKD 3436
D+ W P CE S I + D
Sbjct: 284 DSKWNPSPPACEPNSCINLPD 304
Score = 56.2 bits (134), Expect = 6e-07
Identities = 60/241 (24%), Positives = 95/241 (39%), Gaps = 35/241 (14%)
Query: 2175 VYQAYQL-QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRN 2231
VY + + + C P RNG V I D + G I F C G+ LIG++ C +
Sbjct: 103 VYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG 162
Query: 2232 WNHPLPRCEAL-CGGNITAMNG------TIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN 2284
W+HPLP+CE + C NG Y+ G+ Y + F L+ + N
Sbjct: 163 WSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTY-SCDPRFSLLGHASISCTVEN 221
Query: 2285 FTV---LQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSG 2341
T+ + P + IT P + + +Y+ + I+ K F G
Sbjct: 222 ETIGVWRPSPPTCEKITC------RKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRG 275
Query: 2342 FFVLSYHAYQLRVCQPPPPVPNAEI---------------LTEDDEFEIGDIIRYQCLPG 2386
V+ A PP PN+ I T++D + +G ++RY+C PG
Sbjct: 276 SSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPG 335
Query: 2387 F 2387
+
Sbjct: 336 Y 336
Score = 50.4 bits (119), Expect = 3e-05
Identities = 112/479 (23%), Positives = 168/479 (35%), Gaps = 108/479 (22%)
Query: 1305 VYTSFEL-SHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERR-A 1362
VY +F + C PG + G GS I + C+ G+ L GS+ +C +R
Sbjct: 103 VYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG 162
Query: 1363 WDYPLPSC-IAEC-------GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVS 1414
W +PLP C I +C GR GE + Y + + C DP
Sbjct: 163 WSHPLPQCEIVKCKPPPDIRNGRHSGEEN------FYAYGFSVTYSC------DP-RFSL 209
Query: 1415 LQFLAFDTEASHDILRVW-DGPPENDMLL---KEISGSLIPEGIHSTLNIVTIQFDTDFY 1470
L + ++ + VW PP + + ++S + G N DT +
Sbjct: 210 LGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYK----DTIVF 265
Query: 1471 ISKSGFAIQFSSSV-----------ATACRD------PGVPMNG------TRNGDGREPG 1507
+ GF ++ SS + AC P +P D G
Sbjct: 266 KCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVG 325
Query: 1508 DTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHP 1567
+ ++C PGY+ +E T I +N W P C A C ++G I
Sbjct: 326 TVLRYRCHPGYKPTTDEPTTVICQKN-LRWTPYQG-CEALCCPEPKLNNGEITQ------ 377
Query: 1568 YPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQD-SKLPER 1626
+ SR + + D ISFS F I G + SP S D P +
Sbjct: 378 HRKSRPANHCVYFYGDE------ISFSCHETSRFSAICQGDGTWSPRTPSCGDICNFPPK 431
Query: 1627 IESSSNTMHLAFRSDGSVSY----------TGFHLEYKAKL--------------RESCF 1662
I H ++ S S+ G+ L +AKL + C
Sbjct: 432 I------AHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCR 485
Query: 1663 DPGNIMNGTRLGMD---YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
P ++NG RL +D Y VT CD+GY + G ++TC G W +P C
Sbjct: 486 KP-ELVNG-RLSVDKDQYVEPENVTIQCDSGYGVVGPQSITC----SGNRTWYPEVPKC 538
Score = 49.7 bits (117), Expect = 5e-05
Identities = 96/440 (21%), Positives = 155/440 (35%), Gaps = 71/440 (16%)
Query: 1677 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNR--ALPSCHAPCGSRSTGSEGTVL 1734
+K G+T+ Y C GYV + +ST T DG +N C P R+ E
Sbjct: 71 FKTGTTLKYTCLPGYV-RSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVE---- 125
Query: 1735 SPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSL--- 1791
+ S G +S + + F + G + + D + P Q ++
Sbjct: 126 ---IKTDLSFGSQIEFSCS--EGFFLIGSTTS-RCEVQDRGVGWSHPLPQCEIVKCKPPP 179
Query: 1792 ---SGSHSGESLPLSSGNQITI----RFTSVG----PITAKGFHF-VYQAVPRTSSTQCS 1839
+G HSGE + G +T RF+ +G T + V++ P T
Sbjct: 180 DIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC 239
Query: 1840 SVPEPRFGRRI---GNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1896
P+ G + G + +++F C G++L GS I C+ + ++WN S P C
Sbjct: 240 RKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCD----ADSKWNPSPPAC- 294
Query: 1897 VPCGGILTKRKGTILSPGYPEPYDNNLNCV-----------WKITVPEGAGIQVQVVSFA 1945
P I YP P ++ V +K T E + Q
Sbjct: 295 EPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQ----- 349
Query: 1946 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 2005
W + P+L +G H + +N+ + +IS S
Sbjct: 350 KNLRWTPYQGCEALCCPEPKLN--NGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSA 407
Query: 2006 AIGLDSCPEPQTPSSG-------------IKIGDRY-MVGDVVSFQCDQGYSLQGHSHIT 2051
D P+TPS G K Y + + ++CD+GY L G + ++
Sbjct: 408 ICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLS 467
Query: 2052 CMPGPVRRWNYPIPICLAQC 2071
C W+ P P C A C
Sbjct: 468 C---SYSHWSAPAPQCKALC 484
Score = 47.0 bits (110), Expect = 3e-04
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
C PGE NG+ I +D S GS ++FSC E + L G+ + C+ + + WS P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCE-VQDRGVGWSHPLPQCE 171
Query: 505 VKTC 508
+ C
Sbjct: 172 IVKC 175
Score = 44.7 bits (104), Expect = 0.002
Identities = 46/232 (19%), Positives = 94/232 (40%), Gaps = 35/232 (15%)
Query: 986 FSIGSTVSFSCDSGYRLSHEEP--LLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGY 1043
+ +G+ + + C GY+ + +EP ++C+KN W+ P C+ALC + + +G I +
Sbjct: 322 YVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQ--H 378
Query: 1044 PEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGS--DL 1101
+ P + +C + +G + F+ H + + I + P G +
Sbjct: 379 RKSRPAN-HCVY----FYGDEISFSCH-----ETSRFSAICQGDGTWSPRTPSCGDICNF 428
Query: 1102 PPTINAG------LYGNFRAQLRFISD---FSISYEGFNITFSEYNLEPCEDPGIPQYGS 1152
PP I G Y F+ ++ + D + + ++S ++ + + +
Sbjct: 429 PPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPE 488
Query: 1153 RIGFNFGIG-------DTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
+ + + +T C SGY + G I C G R W +P+C
Sbjct: 489 LVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITC--SGNRTWYPEVPKC 538
Score = 43.1 bits (100), Expect = 0.005
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
C P + NG+ G + ++ G +V +SCD + L G SI+C E W P C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 504 KVKTC 508
+ TC
Sbjct: 235 EKITC 239
Score = 42.7 bits (99), Expect = 0.007
Identities = 74/333 (22%), Positives = 114/333 (34%), Gaps = 92/333 (27%)
Query: 1488 CRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
CR P V +G G DT+VF+C G+ L+G I C +++ W PSPP C
Sbjct: 239 CRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC-DADSK--WNPSPPACE 295
Query: 1546 APCGGNLTGSSGFILSPNFPH------PYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1599
NL P+ PH P P D YV+ + + P Y
Sbjct: 296 PNSCINL---------PDIPHASWETYPRPTKEDV---------YVVGTV-LRYRCHPGY 336
Query: 1600 DFLYIYDGPDSNSPLIGSFQDSK------------LPE-RIESSSNTMHLAFR-SDGSVS 1645
P ++ P Q + PE ++ + T H R ++ V
Sbjct: 337 K-------PTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVY 389
Query: 1646 YTGFHLEYK-----------------AKLRESCFD----PGNIMNGTRLGMDYKLGST-- 1682
+ G + + + SC D P I +G YK S+
Sbjct: 390 FYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHG-----HYKQSSSYS 444
Query: 1683 -----VTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS-RSTGSEGTVLSP 1736
+ Y CD GY+L G + L+C W+ P C A C +V
Sbjct: 445 FFKEEIIYECDKGYILVGQAKLSCSYSH-----WSAPAPQCKALCRKPELVNGRLSVDKD 499
Query: 1737 NY--PKNYSVGHNCVYSIAVPKEFVVFGQFVFF 1767
Y P+N ++ + Y + P+ G ++
Sbjct: 500 QYVEPENVTIQCDSGYGVVGPQSITCSGNRTWY 532
Score = 42.0 bits (97), Expect = 0.011
Identities = 57/237 (24%), Positives = 77/237 (32%), Gaps = 64/237 (27%)
Query: 970 CLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 1025
C PG +G+ D S GS + FSC G+ L CE + WSHPLP C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 1026 L-C--GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1082
+ C D+R + G FY + T++ D F L H
Sbjct: 173 VKCKPPPDIRNGRHS----GEENFYAYGFSVTYSCD-----------PRFSLLGHASISC 217
Query: 1083 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1142
EN + PPT IT C
Sbjct: 218 TVENETIG------VWRPSPPTCE------------------------KIT--------C 239
Query: 1143 EDPGIPQYGSRIGFN--FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
P + GF + DT+ F C G+ L G+S I C + W+ P C
Sbjct: 240 RKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSK--WNPSPPAC 294
Score = 41.2 bits (95), Expect = 0.019
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 1661 CFDPGNIMNGTRLGMD--YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
C P +I NG G + Y G +VTY CD + L G+++++C + ++ W + P+C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 1719 HAPCGSRSTGSEGTVLS 1735
+ S G ++S
Sbjct: 235 EKITCRKPDVSHGEMVS 251
Score = 40.4 bits (93), Expect = 0.033
Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 3/40 (7%)
Query: 2204 QTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2243
+ I +EC GY L+G + L+C + +W+ P P+C+ALC
Sbjct: 448 EEIIYECDKGYILVGQAKLSCSYS---HWSAPAPQCKALC 484
Score = 40.0 bits (92), Expect = 0.043
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERL--QMDGAPPVC 2412
C+PPP + N E++ + G + Y C P F+L+G+A ++C + +PP C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 2413 Q 2413
+
Sbjct: 235 E 235
Score = 38.5 bits (88), Expect = 0.12
Identities = 62/263 (23%), Positives = 87/263 (33%), Gaps = 65/263 (24%)
Query: 2197 GNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYS 2256
G + TI F+C G+ L G+S + C WN P CE N I
Sbjct: 254 GPIYNYKDTIVFKCQKGFVLRGSSVIHC--DADSKWNPSPPACEP---------NSCINL 302
Query: 2257 PGYP----DEYPNFQDCFWLVRVPPGNGIYINFTVLQT------EPIYDFITV------- 2299
P P + YP P +Y+ TVL+ +P D T
Sbjct: 303 PDIPHASWETYPR----------PTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 2300 ----WDG--------PDQNSPQIGQF-SGNTALESVYSTSNQILIKFHSDFTTSGFFVLS 2346
+ G P N+ +I Q A VY ++I H TS F +
Sbjct: 353 RWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE---TSRFSAIC 409
Query: 2347 YH--AYQLR------VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2398
+ R +C PP + + + I Y+C G+ LVG A L+C
Sbjct: 410 QGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCS 469
Query: 2399 LGERLQMDGAPPVCQVLCPANEL 2421
P C+ LC EL
Sbjct: 470 YS---HWSAPAPQCKALCRKPEL 489
Score = 37.0 bits (84), Expect = 0.36
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 1142 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-V 1198
C PG + G I + G + FSCS G+ L G++ C R V WS PLP+C +
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 1199 AEC 1201
+C
Sbjct: 173 VKC 175
Score = 36.6 bits (83), Expect = 0.47
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 786 YNTFG-HNECPDPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVM 843
YNTF + C PG N + + GS I C EGF G+ T C + D V
Sbjct: 104 YNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLI-GSTTSRCEVQDRGVG 162
Query: 844 WSGLIPKC 851
WS +P+C
Sbjct: 163 WSHPLPQC 170
Score = 36.6 bits (83), Expect = 0.47
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 620 EKESCGDPGTPLYGIREGDG--FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
EK +C P + G G ++ +D + F+CQ GF L G I C +++W+ + P C
Sbjct: 235 EKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPAC 294
Score = 36.2 bits (82), Expect = 0.61
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 2012 CPEPQTPSSGIKIG-DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2067
C +P+ + + + D+Y+ + V+ QCD GY + G ITC R W +P C
Sbjct: 484 CRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGN--RTWYPEVPKC 538
Score = 35.4 bits (80), Expect = 1.0
Identities = 51/239 (21%), Positives = 83/239 (34%), Gaps = 56/239 (23%)
Query: 447 PDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVK 506
PD E G ++ T+ F C + +VL+G+ I C + + W+ P C+
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC----DADSKWNPSPPACEPN 297
Query: 507 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
+C + P ++ + P + D V+V+ V + GY T
Sbjct: 298 SCINLPDIPHASWETYPRPTKED-----VYVVGTV----------LRYRCHPGYKPTT-- 340
Query: 567 DGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGD 626
+P TV + + W Q E++ K+N EI +
Sbjct: 341 -----DEPTTV-------------ICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSR 382
Query: 627 PGTP-LYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP----ICIFP 680
P +Y + FS + RF S +CQ + WS P IC FP
Sbjct: 383 PANHCVYFYGDEISFSCHETSRF------------SAICQGDGTWSPRTPSCGDICNFP 429
Score = 32.7 bits (73), Expect = 6.8
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
Query: 111 FSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVG------DKIRYSC 164
FS TS F+ G + ++ SCG+ P + +G ++I Y C
Sbjct: 397 FSCHETSRFSAICQGDGTWSP--RTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYEC 454
Query: 165 VTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
GYIL G +L+C + + W P P C+A
Sbjct: 455 DKGYILVGQAKLSC-----SYSHWSAPAPQCKA 482
Score = 32.3 bits (72), Expect = 8.9
Identities = 11/40 (27%), Positives = 20/40 (50%)
Query: 638 DGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
D + + + +C G+ ++G +SI C N W +P C
Sbjct: 499 DQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 146 bits (369), Expect = 3e-34
Identities = 107/304 (35%), Positives = 146/304 (48%), Gaps = 29/304 (9%)
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2184
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2185 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2244
RP R G T+G + C PGY L + RCEA CG
Sbjct: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
Query: 2245 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2300
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQLRVCQPPP 2359
G +S G+F G+ E + S N + ++F SD T S F + + + QPP
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPR 712
Query: 2360 PVPN 2363
P+
Sbjct: 713 GRPH 716
Score = 144 bits (364), Expect = 1e-33
Identities = 102/301 (33%), Positives = 142/301 (47%), Gaps = 30/301 (9%)
Query: 1372 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1427
A CGG K + G I SP YP Y + C+W I+V G V L F +F+ E ++D
Sbjct: 433 AICGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1428 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1487
L V DG E+ L+ G P+ I ST + + ++F +D I+K+GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAP 1547
R P G + CDPGYEL ++R C A
Sbjct: 552 SR----PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRR-----------------CEAA 590
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CGG LT +G I SP +P YP +++C W + Y ISL F F E N YDF+
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
+ G ++S L G F S+ PE I S N M + F+SD +VS GF + ++ R +
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQP 710
Query: 1664 P 1664
P
Sbjct: 711 P 711
Score = 136 bits (343), Expect = 3e-31
Identities = 92/300 (30%), Positives = 146/300 (48%), Gaps = 32/300 (10%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 2014
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
Query: 2015 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
P ++ + + S++C D GY L P +R C A CG
Sbjct: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
Query: 2073 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2128
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2129 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2188
SG + S + G+ G + P + S + + F SD + +K+GF + + + + PR
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPR 712
Score = 136 bits (343), Expect = 3e-31
Identities = 93/291 (31%), Positives = 140/291 (48%), Gaps = 32/291 (10%)
Query: 681 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLA 736
C + G + SP+YP+ Y + CIW I G + L+F F++E +D+L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 737 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH-NECP 795
V+DG S S ++G + G E P + S S L L+F +D S++ GF + N F +EC
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDECS 552
Query: 796 DPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPC 855
P R G CE+ + T G+ +C D + +C A C
Sbjct: 553 RPN------RGG------------CEQRCLNTLGSYKCSC---DPGYELAPDKRRCEAAC 591
Query: 856 GGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEV 911
GG + +G I SPGWP Y + NC W + A + I + F+ F+TE N YD +EV
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 912 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYES 962
G S L G + G++ P+ + S N + + F +DN+ S GFK H+ S
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 136 bits (342), Expect = 4e-31
Identities = 98/300 (32%), Positives = 143/300 (47%), Gaps = 40/300 (13%)
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1662 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
P R G + + +T+ Y CD GY L P R C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
Query: 1719 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1774
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1775 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1831
VEV G T S L GS E + S N + + F S ++ KGF HF + P
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRP 706
Score = 124 bits (311), Expect = 2e-27
Identities = 84/283 (29%), Positives = 138/283 (48%), Gaps = 29/283 (10%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 563
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
Query: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 683
C P G E + + C G+EL +K C C
Sbjct: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
Query: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 739
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
Query: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 782
G + +S + G F G+E P +TS + +R+EF++D+++S +GF
Sbjct: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 115 bits (287), Expect = 1e-24
Identities = 88/291 (30%), Positives = 126/291 (43%), Gaps = 38/291 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
N G + L + + SC GY L + R E
Sbjct: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 255
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 256 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 113 bits (283), Expect = 3e-24
Identities = 84/291 (28%), Positives = 132/291 (45%), Gaps = 32/291 (10%)
Query: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 908
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF +++
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EVD 549
Query: 969 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 1028
C P G + + SCD GY L+ ++ C+A CG
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 1029 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLIT 1084
G + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 1085 ENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITF 1134
+ L + GS+ P I + Y N R + F SD ++S +GF F
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHF 700
Score = 113 bits (282), Expect = 4e-24
Identities = 84/294 (28%), Positives = 128/294 (43%), Gaps = 35/294 (11%)
Query: 1720 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1774
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1775 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1834
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1835 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
S E R +G S C+PGY E P+
Sbjct: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
Query: 1895 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1950
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2004
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 105 bits (262), Expect = 8e-22
Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 34/295 (11%)
Query: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
++ C P R G + SC GY L RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
+ G + L G F G S + ++S N + +EF SD + +GF+ + S
Sbjct: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 100 bits (250), Expect = 2e-20
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2353
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
Query: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
C P +CL +G+ +C G L D C+
Sbjct: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2469
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 2470 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 90.9 bits (224), Expect = 2e-17
Identities = 114/438 (26%), Positives = 176/438 (40%), Gaps = 79/438 (18%)
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 256 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE-------A 433
Query: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 371
G++++ G I + P D S V I ++SE V +T ++ ++ + S
Sbjct: 434 ICGGDVKK----DYGHIQSPNYPDDYRPSKVCIWRI-QVSEGFHVGLT-FQSFEIERHDS 487
Query: 372 --KDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 429
D L ++S+ R+ +K D KS +L+
Sbjct: 488 CAYDYLEVRDGHSESSTLIGRYC--------------GYEKPDDIKSTSSRLW------- 526
Query: 430 KFSILNEGGIKTAS---NLCPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAK 482
+++G I A N + E R G + +LGS + SCD Y L K
Sbjct: 527 -LKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGS-YKCSCDPGYELAPDK 584
Query: 483 SITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVN 542
C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 585 R-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA-P 624
Query: 543 TNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQMW 598
T I + F+ F+ E G D D EV T L G F P++I S + M
Sbjct: 625 TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMR 682
Query: 599 LHLQTDESVGSVGFKVNY 616
+ ++D +V GFK ++
Sbjct: 683 VEFKSDNTVSKKGFKAHF 700
Score = 73.9 bits (180), Expect = 3e-12
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 13/120 (10%)
Query: 690 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 745
G SP+YP GY +++C+W I PG +I L+F DL +D++ V+DG ++
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT---------FGHNECPD 796
P+ G F G+++P + S L +EF++ + G+GF Y +GH + P+
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPN 450
Score = 70.5 bits (171), Expect = 3e-11
Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 80
CGG L LNG+I SPG+P YP NC W ++A + RI + F F E +YD++
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
+ G + + G P +TS + + SD VS GFK ++ + +
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPAL-- 708
Query: 141 PGVPPKGVLYGTRFDVGDKIR 161
PP+G + +F V + R
Sbjct: 709 --QPPRGRPHQLKFRVQKRNR 727
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2345
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 62.8 bits (151), Expect = 6e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 451 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 498
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
Query: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 557
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
Query: 558 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 614
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
Query: 615 NYKEIEKESCGDPGTPLYG 633
Y+ I CG YG
Sbjct: 430 VYEAI----CGGDVKKDYG 444
Score = 62.4 bits (150), Expect = 8e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1655
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 59.7 bits (143), Expect = 5e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2482
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
Query: 2483 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2540
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
Query: 2541 ISQTGGQLNSVVRWACDRGFRL 2562
+ L S + +CD G+ L
Sbjct: 560 EQRCLNTLGS-YKCSCDPGYEL 580
Score = 59.3 bits (142), Expect = 7e-08
Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 254 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
YLE+ SE T+ G P I S + L L FV+D + GF+ +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 310 HTTSTGELEEHNRTTTGAIAVASTP 334
+ G E+ T G+ + P
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCSCDP 576
Score = 58.5 bits (140), Expect = 1e-07
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 953 NNGFKIHYESV 963
GF YE++
Sbjct: 424 GKGFFAVYEAI 434
Score = 57.4 bits (137), Expect = 3e-07
Identities = 36/113 (31%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEEL 133
+ DG R R G LP P+ ST S + S GF YE +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1251
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1252 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Query: 1309 F-------ELSHCEDPGIP 1320
+ H + P P
Sbjct: 434 ICGGDVKKDYGHIQSPNYP 452
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
Query: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1828 QAV 1830
+A+
Sbjct: 432 EAI 434
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1365 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1424
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1425 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1478
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 1027 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1082
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1083 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1120
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Score = 38.9 bits (89), Expect = 0.095
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
Query: 2531 TPESPPHGYIIS 2542
+G+I S
Sbjct: 437 GDVKKDYGHIQS 448
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 145 bits (367), Expect = 6e-34
Identities = 102/280 (36%), Positives = 137/280 (48%), Gaps = 28/280 (10%)
Query: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2184
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2185 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2244
RP R G T+G + C PGY L + RCEA CG
Sbjct: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
Query: 2245 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2300
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2340
G +S G+F G+ E + S N + ++F SD T S
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVS 692
Score = 144 bits (362), Expect = 2e-33
Identities = 105/310 (33%), Positives = 146/310 (47%), Gaps = 31/310 (10%)
Query: 1372 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1427
A CGG K + G I SP YP Y + C+W I+V G V L F +F+ E ++D
Sbjct: 433 AICGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1428 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1487
L V DG E+ L+ G P+ I ST + + ++F +D I+K+GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAP 1547
R P G + CDPGYEL ++R C A
Sbjct: 552 SR----PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRR-----------------CEAA 590
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CGG LT +G I SP +P YP +++C W + Y ISL F F E N YDF+
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
+ G ++S L G F S+ PE I S N M + F+SD +VS GF + + L E D
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVL-EGAGD 709
Query: 1664 PGNIMNGTRL 1673
+ ++G L
Sbjct: 710 RHSHLSGLEL 719
Score = 138 bits (347), Expect = 1e-31
Identities = 94/292 (32%), Positives = 141/292 (48%), Gaps = 32/292 (10%)
Query: 681 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLA 736
C + G + SP+YP+ Y + CIW I G + L+F F++E +D+L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 737 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH-NECP 795
V+DG S S ++G + G E P + S S L L+F +D S++ GF + N F +EC
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDECS 552
Query: 796 DPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPC 855
P R G CE+ + T G+ +C D + +C A C
Sbjct: 553 RPN------RGG------------CEQRCLNTLGSYKCSC---DPGYELAPDKRRCEAAC 591
Query: 856 GGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEV 911
GG + +G I SPGWP Y + NC W + A + I + F+ F+TE N YD +EV
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 912 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV 963
G S L G + G++ P+ + S N + + F +DN+ S GFK H+ SV
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSV 703
Score = 135 bits (341), Expect = 6e-31
Identities = 90/284 (31%), Positives = 140/284 (49%), Gaps = 32/284 (11%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 2014
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
Query: 2015 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
P ++ + + S++C D GY L P +R C A CG
Sbjct: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
Query: 2073 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2128
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2129 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2172
SG + S + G+ G + P + S + + F SD + +K+GF
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 135 bits (340), Expect = 7e-31
Identities = 97/294 (32%), Positives = 141/294 (47%), Gaps = 40/294 (13%)
Query: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1662 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
P R G + + +T+ Y CD GY L P R C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
Query: 1719 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1774
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1775 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HF 1825
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 124 bits (311), Expect = 2e-27
Identities = 84/283 (29%), Positives = 138/283 (48%), Gaps = 29/283 (10%)
Query: 508 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 563
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
Query: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 683
C P G E + + C G+EL +K C C
Sbjct: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
Query: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 739
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
Query: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 782
G + +S + G F G+E P +TS + +R+EF++D+++S +GF
Sbjct: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 115 bits (288), Expect = 8e-25
Identities = 87/314 (27%), Positives = 139/314 (44%), Gaps = 36/314 (11%)
Query: 1720 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1774
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1775 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1834
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1835 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
S E R +G S C+PGY E P+
Sbjct: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
Query: 1895 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1950
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + ++ L+
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSV-LE 705
Query: 2011 SCPEPQTPSSGIKI 2024
+ + SG+++
Sbjct: 706 GAGDRHSHLSGLEL 719
Score = 115 bits (287), Expect = 1e-24
Identities = 88/291 (30%), Positives = 126/291 (43%), Gaps = 38/291 (13%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
N G + L + + SC GY L + R E
Sbjct: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 255
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 256 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 113 bits (283), Expect = 3e-24
Identities = 84/291 (28%), Positives = 132/291 (45%), Gaps = 32/291 (10%)
Query: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 908
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF +++
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EVD 549
Query: 969 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 1028
C P G + + SCD GY L+ ++ C+A CG
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 1029 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLIT 1084
G + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 1085 ENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITF 1134
+ L + GS+ P I + Y N R + F SD ++S +GF F
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHF 700
Score = 105 bits (262), Expect = 8e-22
Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 34/295 (11%)
Query: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
++ C P R G + SC GY L RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
+ G + L G F G S + ++S N + +EF SD + +GF+ + S
Sbjct: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 100 bits (250), Expect = 2e-20
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2353
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
Query: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
C P +CL +G+ +C G L D C+
Sbjct: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
Query: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2469
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 2470 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 94.0 bits (232), Expect = 2e-18
Identities = 119/456 (26%), Positives = 184/456 (40%), Gaps = 80/456 (17%)
Query: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 256 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE-------A 433
Query: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 371
G++++ G I + P D S V I ++SE V +T ++ ++ + S
Sbjct: 434 ICGGDVKK----DYGHIQSPNYPDDYRPSKVCIWRI-QVSEGFHVGLT-FQSFEIERHDS 487
Query: 372 --KDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 429
D L ++S+ R+ +K D KS +L+
Sbjct: 488 CAYDYLEVRDGHSESSTLIGRYC--------------GYEKPDDIKSTSSRLW------- 526
Query: 430 KFSILNEGGIKTAS---NLCPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAK 482
+++G I A N + E R G + +LGS + SCD Y L K
Sbjct: 527 -LKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGS-YKCSCDPGYELAPDK 584
Query: 483 SITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVN 542
C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 585 R-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA-P 624
Query: 543 TNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQMW 598
T I + F+ F+ E G D D EV T L G F P++I S + M
Sbjct: 625 TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMR 682
Query: 599 LHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGI 634
+ ++D +V GFK ++ + E GD + L G+
Sbjct: 683 VEFKSDNTVSKKGFKAHFFSV-LEGAGDRHSHLSGL 717
Score = 73.9 bits (180), Expect = 3e-12
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 13/120 (10%)
Query: 690 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 745
G SP+YP GY +++C+W I PG +I L+F DL +D++ V+DG ++
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT---------FGHNECPD 796
P+ G F G+++P + S L +EF++ + G+GF Y +GH + P+
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPN 450
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2345
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 62.8 bits (151), Expect = 6e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 451 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 498
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
Query: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 557
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
Query: 558 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 614
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
Query: 615 NYKEIEKESCGDPGTPLYG 633
Y+ I CG YG
Sbjct: 430 VYEAI----CGGDVKKDYG 444
Score = 62.4 bits (150), Expect = 8e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1655
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 59.7 bits (143), Expect = 5e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2482
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
Query: 2483 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2540
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
Query: 2541 ISQTGGQLNSVVRWACDRGFRL 2562
+ L S + +CD G+ L
Sbjct: 560 EQRCLNTLGS-YKCSCDPGYEL 580
Score = 59.3 bits (142), Expect = 7e-08
Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 254 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
YLE+ SE T+ G P I S + L L FV+D + GF+ +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 310 HTTSTGELEEHNRTTTGAIAVASTP 334
+ G E+ T G+ + P
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCSCDP 576
Score = 58.5 bits (140), Expect = 1e-07
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 953 NNGFKIHYESV 963
GF YE++
Sbjct: 424 GKGFFAVYEAI 434
Score = 57.4 bits (137), Expect = 3e-07
Identities = 36/113 (31%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEEL 133
+ DG R R G LP P+ ST S + S GF YE +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1251
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1252 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Query: 1309 F-------ELSHCEDPGIP 1320
+ H + P P
Sbjct: 434 ICGGDVKKDYGHIQSPNYP 452
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
Query: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1828 QAV 1830
+A+
Sbjct: 432 EAI 434
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1365 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1424
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1425 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1478
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 1027 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1082
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1083 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1120
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Score = 38.9 bits (89), Expect = 0.095
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
Query: 2531 TPESPPHGYIIS 2542
+G+I S
Sbjct: 437 GDVKKDYGHIQS 448
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 134 bits (337), Expect = 2e-30
Identities = 128/460 (27%), Positives = 198/460 (43%), Gaps = 62/460 (13%)
Query: 2887 MCKVVNCSDPGIPANSKRESKIEHGNF---TY--GTVVFYDCNPGYFLFGSSVLICQPNG 2941
+C +C++ +P +R ++I G++ TY GT Y C PGY G+ +++C+ G
Sbjct: 15 ICVAEDCNE--LPP--RRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KG 69
Query: 2942 QWD--KPLPECIMIDCGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSS-RTC 2995
+W PL +C CGHPG P + G + +G Y+C LLG+ + R C
Sbjct: 70 EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYREC 129
Query: 2996 QLNGHWSGSQPHCSGDATGTCGDPGTPGHGS------RQESNFRTKSTVRYACDTGYILH 3049
+G W+ P C C P +G + + VR+ C++GY +
Sbjct: 130 DTDG-WTNDIPICE---VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 3050 GSEERTCLANGSWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCMEGY 3105
G EE C +G W+ +P+C + C +P G+ + K+ + F Y C GY
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ----YKCNMGY 241
Query: 3106 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG----LRYGDDYVVGQNVSYMCQP 3161
S CT +G W LP+C SC +P IP NG LR + G ++Y C+
Sbjct: 242 EYSERGDAVCTESG-WR-PLPSCEEKSCDNPYIP-NGDYSPLRI--KHRTGDEITYQCRN 296
Query: 3162 GYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNF-------DWGFS 3214
G+ G+ + CT G W P C C P I +G L N G
Sbjct: 297 GFYPATRGNTAK-CTSTG-WIPA-PRCTLKPCDY-PDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 3215 ISYICSPGYEL---SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQ 3270
SY C +E S+ + C +G WS VP CL K C P + + G+ F+
Sbjct: 353 YSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLRK-CYFPYLENGYNQNHGRKFVQG 409
Query: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3310
+ +C+ + L + T + + WS +P CI + T
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENGWS-PTPRCIRVSFT 448
Score = 120 bits (300), Expect = 3e-26
Identities = 122/458 (26%), Positives = 183/458 (39%), Gaps = 67/458 (14%)
Query: 2587 CQAISCGIPKAPTNGGILTTD-----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2641
C A C N ILT Y GT+ Y C GYR + VC+ G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIM--VCRK-GEWV 72
Query: 2642 NHNKTPRCVVVTC--PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASI-E 2698
N +C C P F G + + G+ +EY K V++C+ GY LG + E
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPF----GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRE 128
Query: 2699 CLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGT------QTSYGSTAIFTCDLGFMLV 2752
C +G W N+ P C+++ C + P NG + + + +G F C+ G+ +
Sbjct: 129 CDTDG---WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 2753 GSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDT--VVYQCNPGFRLI 2810
G C G WS+ + +C+ C P+ ++NG I + Y++ Y+CN G+
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPD-VINGSPISQKIIYKENERFQYKCNMGYEYS 244
Query: 2811 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSP--------IYGRTSGNGFNFNDVVTFSCN 2862
+C + W LPSC SC +P P I RT D +T+ C
Sbjct: 245 ERGDAVCTES-GWR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRT-------GDEITYQCR 295
Query: 2863 IGY--LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF--TYGTV 2918
G+ +G T A+C + W P P C + C P I + F G
Sbjct: 296 NGFYPATRGNT-AKC-TSTGWI-PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 2919 VFYDCNPGYFLFGSSV---LICQPNGQWDKPLPECIMIDCGHP----GVPPNAVLSGEKY 2971
Y C+ + S + C +G W +P C+ C P G N G K+
Sbjct: 353 YSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLR-KCYFPYLENGYNQN---HGRKF 406
Query: 2972 TFGSTVHYSC-TGKRSLLGQSSRTCQLNGHWSGSQPHC 3008
G ++ +C G Q++ TC NG WS + P C
Sbjct: 407 VQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT-PRC 442
Score = 100 bits (248), Expect = 3e-20
Identities = 108/417 (25%), Positives = 155/417 (37%), Gaps = 82/417 (19%)
Query: 3025 GSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP--ECKAVQCGNPGTTAN 3082
GS + + + Y C GY G+ C G W P +C+ CG+PG T
Sbjct: 35 GSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVALNPLRKCQKRPCGHPGDTPF 93
Query: 3083 GKVFRIDGTTFSSSV--IYSCMEGYILSGP-SVRQCTANGTWSGTLPNCTIISCGDPGIP 3139
G G F V +Y+C EGY L G + R+C +G W+ +P C ++ C P
Sbjct: 94 GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAP 152
Query: 3140 ANG------LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTC 3193
NG + +Y GQ V ++C GY +E G C+ +G WS P C ++C
Sbjct: 153 ENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE--GDEEMHCSDDGFWSKEKPKCVEISC 210
Query: 3194 PTPPQISNGRL-EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3252
+P I+ + + + Y C+ GYE S C +G W +P C K C
Sbjct: 211 KSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCD 268
Query: 3253 DPGI------PAQGK-REGKSFIYQSEVSF-------------------------SCNFP 3280
+P I P + K R G YQ F C++P
Sbjct: 269 NPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYP 328
Query: 3281 FILVGS-------------------STRICQADGTWSGS---SPHCIE-------PTQTS 3311
I G S + T SGS HC + P
Sbjct: 329 DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRK 388
Query: 3312 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL-QGSTTRTCLPDLTWSGIQPECI 3367
C P + +QN+ F G + C G+ L + TT TC+ + WS P CI
Sbjct: 389 CYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMEN-GWSP-TPRCI 443
Score = 99.8 bits (247), Expect = 5e-20
Identities = 119/456 (26%), Positives = 170/456 (37%), Gaps = 62/456 (13%)
Query: 2714 CQIISCGELPTPPN-----GNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2768
C C ELP N G+ G+ AI+ C G+ +G+ + C G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 2769 ET--RCLAGHCGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGS-SVRICQQDHN 2822
+C CG P G G + Y VY CN G++L+G + R C D
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTD-G 133
Query: 2823 WSGQLPSCVPVSCGHPGSPIYGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKAQCQ 2876
W+ +P C V C +P G+ + ++F V F CN GY ++G + C
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 2877 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKI---EHGNFTYGTVVFYDCNPGYFLFGSS 2933
+ WS P C ++C P + S KI E+ F Y CN GY
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ------YKCNMGYEYSERG 247
Query: 2934 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSC-TGKRSLLGQ 2990
+C +G W +PLP C C +P + PN S K+ G + Y C G
Sbjct: 248 DAVCTESG-W-RPLPSCEEKSCDNPYI-PNGDYSPLRIKHRTGDEITYQCRNGFYPATRG 304
Query: 2991 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFR-------TKSTVRYACD 3043
++ C G W + P C+ C P HG N R Y CD
Sbjct: 305 NTAKCTSTG-WIPA-PRCT---LKPCDYPDIK-HGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 3044 TGYILHGS---EERTCLANGSWTGRQP---ECKAVQCGNPGTTANGKVFRIDGTTFSSSV 3097
+ + C +G W+ P +C N +G+ F + G S+
Sbjct: 359 EHFETPSGSYWDHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRKF-VQG----KSI 412
Query: 3098 IYSCMEGYIL-SGPSVRQCTANGTWSGTLPNCTIIS 3132
+C GY L + C NG WS T P C +S
Sbjct: 413 DVACHPGYALPKAQTTVTCMENG-WSPT-PRCIRVS 446
Score = 94.7 bits (234), Expect = 1e-18
Identities = 89/352 (25%), Positives = 131/352 (37%), Gaps = 35/352 (9%)
Query: 3095 SSVIYSCMEGYILSGPSVRQCTANGTWSGTLP--NCTIISCGDPGIPANG---LRYGDDY 3149
+ IY C GY G + C G W P C CG PG G L G+ +
Sbjct: 46 TQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 3150 VVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT-- 3207
G Y C GY + L R C +G W+ +P C V C NG++ +
Sbjct: 105 EYGVKAVYTCNEGYQL-LGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAM 162
Query: 3208 ----NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKRE 3263
+ +G ++ ++C+ GY++ + C +G WS E P+C+ C P + G
Sbjct: 163 EPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDV-INGSPI 221
Query: 3264 GKSFIYQSEVSFS--CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG 3321
+ IY+ F CN + +C G W P C E SC+NP +P
Sbjct: 222 SQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEK---SCDNPYIPNGD 276
Query: 3322 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSG--IQPECIPHSCKQPETP-- 3377
+ G + + C+ G TR T +G P C C P+
Sbjct: 277 YSPLRIKHRTGDEITYQCRNGFY---PATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHG 333
Query: 3378 --AHANVVGMDLP-SHGYTLIYTCQPGFFLAGGT--EHRVCRSDNTWTGKVP 3424
H N+ P + G Y C F G+ +H C D W+ VP
Sbjct: 334 GLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP 384
Score = 90.9 bits (224), Expect = 2e-17
Identities = 115/429 (26%), Positives = 159/429 (37%), Gaps = 62/429 (14%)
Query: 2554 WACDRGFRLVGKSSAVCRKSSYGYHAWDA--PVPACQAISCGIPKAPTNGGILTTD---Y 2608
+ C G+R +G VCRK W A P+ CQ CG P G T +
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-----WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 2609 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWR 2668
G + Y CN+GY+L E+ C +DG W+ N P C VV C + + E+G +
Sbjct: 105 EYGVKAVYTCNEGYQLLG-EINYRECDTDG-WT--NDIPICEVVKCLPVTA--PENG--K 156
Query: 2669 IVNGS-----HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELP 2723
IV+ + Y + V F C+ GY G + C +G WS E+P C ISC + P
Sbjct: 157 IVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWS--KEKPKCVEISC-KSP 213
Query: 2724 TPPNGNKIGTQTSYGSTAIF--TCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPE 2781
NG+ I + Y F C++G+ C SG W + C C P
Sbjct: 214 DVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLPS-CEEKSCDNP- 270
Query: 2782 LIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPG 2839
I NG +R D + YQC GF W P C C +P
Sbjct: 271 YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI-PAPRCTLKPCDYPD 329
Query: 2840 SPIYGRTSGNGFNFNDVVTFSCNIG--YLMQGPTKAQCQANRQWSHPPPMCKVVNCS--- 2894
G N F +G Y + + W H ++C+
Sbjct: 330 IKHGGLYHENMRR----PYFPVAVGKYYSYYCDEHFETPSGSYWDH-------IHCTQDG 378
Query: 2895 -DPGIPANSK-------RESKIEHG-NFTYGTVVFYDCNPGYFL-FGSSVLICQPNGQWD 2944
P +P K HG F G + C+PGY L + + C NG W
Sbjct: 379 WSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-W- 436
Query: 2945 KPLPECIMI 2953
P P CI +
Sbjct: 437 SPTPRCIRV 445
Score = 85.9 bits (211), Expect = 7e-16
Identities = 102/389 (26%), Positives = 152/389 (39%), Gaps = 60/389 (15%)
Query: 2529 CSTPESPPHGYIISQTGGQLNSVVR--WACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPA 2586
C P P G G V+ + C+ G++L+G+ + W +P
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTNDIPI 140
Query: 2587 CQAISCGIPKAPTNGGILTT------DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2640
C+ + C AP NG I+++ +Y G V + CN GY++ E C DG W
Sbjct: 141 CEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDE--EMHCSDDGFW 198
Query: 2641 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH------YEYKTKVVFSCDPGYHGLGP 2694
S + P+CV ++C S + ++NGS Y+ + + C+ GY
Sbjct: 199 S--KEKPKCVEISCKSPD----------VINGSPISQKIIYKENERFQYKCNMGYEYSER 246
Query: 2695 ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFM-L 2751
C +G WR P C+ SC + P PNG+ + + G + C GF
Sbjct: 247 GDAVCTESG---WR-PLPSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPA 301
Query: 2752 VGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENY--GYRDTVV-----YQCN 2804
+C S+G W + RC C P+ I +G + EN Y V Y C+
Sbjct: 302 TRGNTAKCTSTG-WIPA-PRCTLKPCDYPD-IKHGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 2805 PGFRLIGSSV---RICQQDHNWSGQLPSCVPVSCGHPG-SPIYGRTSGNGFNFNDVVTFS 2860
F S C QD WS +P C+ C P Y + G F + +
Sbjct: 359 EHFETPSGSYWDHIHCTQD-GWSPAVP-CLR-KCYFPYLENGYNQNHGRKFVQGKSIDVA 415
Query: 2861 CNIGY-LMQGPTKAQCQANRQWSHPPPMC 2888
C+ GY L + T C N WS P P C
Sbjct: 416 CHPGYALPKAQTTVTCMEN-GWS-PTPRC 442
Score = 70.5 bits (171), Expect = 3e-11
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 24/259 (9%)
Query: 3188 CRAVTCPTPP-----QISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGE 3242
C A C P +I G + G Y C PGY ++ C G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 3243 VP--QCLPKFCGDPGIPAQGK---REGKSFIYQSEVSFSCNFPFILVGS-STRICQADGT 3296
P +C + CG PG G G F Y + ++CN + L+G + R C DG
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 3297 WSGSSPHCIEPTQTSCENPGVPRHG-----SQNNTFGFQVGSVVQFHCKKGHLLQGSTTR 3351
W+ P C C P +G + + G V+F C G+ ++G
Sbjct: 134 WTNDIPIC---EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 3352 TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR 3411
C D WS +P+C+ SCK P+ + + + Y C G+ + +
Sbjct: 191 HCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGD-A 249
Query: 3412 VCRSDNTWTGKVPICEAGS 3430
VC +++ W +P CE S
Sbjct: 250 VC-TESGWR-PLPSCEEKS 266
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 3332 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP--ECIPHSCKQP-ETPAHA-NVVGMDL 3387
G+ + C+ G+ G+ C W + P +C C P +TP + G ++
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVCRKG-EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNV 103
Query: 3388 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
+G +YTC G+ L G +R C +D WT +PICE + V P
Sbjct: 104 FEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAP 152
Score = 42.4 bits (98), Expect = 0.009
Identities = 44/156 (28%), Positives = 58/156 (37%), Gaps = 14/156 (8%)
Query: 134 QSSSCGNPGVPPKGVLY---GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
Q CG+PG P G G F+ G K Y+C GY L G +T W
Sbjct: 81 QKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTN 136
Query: 191 PVPICRAEDACGGTMRGSSGIISSPSFPN-EYHNNAD----CTWTIVAEPGDTISLIFTD 245
+PIC T + I+SS P+ EYH C E + +
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 246 FQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKN 281
F +EK +EI P I +G I II +N
Sbjct: 197 FWSKEKPKCVEISCKSPDVI--NGSPISQKIIYKEN 230
Score = 41.6 bits (96), Expect = 0.015
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 2355 CQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE 2401
C PP N EILT D + G Y+C PG+ +GN I+ CR GE
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGE 70
Score = 38.5 bits (88), Expect = 0.12
Identities = 57/273 (20%), Positives = 97/273 (35%), Gaps = 28/273 (10%)
Query: 1791 LSGSHSGESLPLSSGNQITIR----FTSVGPITA---KGFHFVYQAVPRTSSTQCSSVPE 1843
L+GS S ++ P G Q + + S+G + KG + + C +
Sbjct: 33 LTGSWSDQTYP--EGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGD 90
Query: 1844 PRFGRRI---GNEFAVGSSVLFDCNPGYILHGSIAIR-CETVPNSLAQWNDSLPTC-IVP 1898
FG GN F G ++ CN GY L G I R C+T W + +P C +V
Sbjct: 91 TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT-----DGWTNDIPICEVVK 145
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1958
C + G I+S + + + G I+ ++ + S +
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Query: 1959 GDNNAPRLGSYSGTTIPHLLNSTSNNLY---LNFQSDISVSAAGFHLEYTAIGLDSCPEP 2015
+ + +G+ I + N + N + S E L SC E
Sbjct: 206 VEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEK 265
Query: 2016 QTPSSGIKIGD------RYMVGDVVSFQCDQGY 2042
+ I GD ++ GD +++QC G+
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGF 298
Score = 38.1 bits (87), Expect = 0.16
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)
Query: 617 KEIEKESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 673
++ +K CG PG +G + G+ F + C G++L+GE + + + W+ +
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTND 137
Query: 674 IPIC-IFPCLSNFTAP-----MGTVLSPDYPEGYG 702
IPIC + CL TAP + + + PD +G
Sbjct: 138 IPICEVVKCLP-VTAPENGKIVSSAMEPDREYHFG 171
Score = 37.4 bits (85), Expect = 0.28
Identities = 13/39 (33%), Positives = 22/39 (56%)
Query: 985 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
++ G V F C+SGY++ +E + C + +WS P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Score = 37.4 bits (85), Expect = 0.28
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 1158 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
+ G + F C+SGY++EG E+ C G WS P+CV
Sbjct: 168 YHFGQAVRFVCNSGYKIEGDEEMHCSDDG--FWSKEKPKCV 206
Score = 35.8 bits (81), Expect = 0.80
Identities = 52/234 (22%), Positives = 92/234 (39%), Gaps = 30/234 (12%)
Query: 1327 SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE-CGGRFKGESSGR 1385
SDQ + G+ IY C PGY G+ ++ C GE A + PL C CG
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALN-PLRKCQKRPCGHPGDTPFGTF 96
Query: 1386 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD-------GPPEN 1438
L+ G F Y ++ ++ + + + DT+ + + + + PEN
Sbjct: 97 TLTGGNVFEY--GVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPEN 154
Query: 1439 DMLLKEISGSLIPEGIHSTLNIV--------TIQFDTDFYISKSGF-AIQFSSSVATACR 1489
K +S ++ P+ + V I+ D + + S GF + + V +C+
Sbjct: 155 G---KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK 211
Query: 1490 DPGVPMNGTRNGDG--REPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1541
P V +NG+ + + ++C+ GYE C + W+P P
Sbjct: 212 SPDV-INGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG----WRPLP 260
Score = 35.0 bits (79), Expect = 1.4
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 9/64 (14%)
Query: 1488 CRDPGVPMNGTRNGDGREP------GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1541
C P NG EP G V F C+ GY+++G+E + C + FW
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC---SDDGFWSKEK 202
Query: 1542 PVCI 1545
P C+
Sbjct: 203 PKCV 206
Score = 34.3 bits (77), Expect = 2.3
Identities = 58/272 (21%), Positives = 94/272 (34%), Gaps = 50/272 (18%)
Query: 1830 VPRTSSTQCSSVPEPRFGRRIGN------EFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1883
+P +C V P G+ + + E+ G +V F CN GY + G + C +
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC----S 193
Query: 1884 SLAQWNDSLPTCI-VPCGGILTKRKGTILSPGYPEP----YDNNLNCVWKITVPEGAGIQ 1938
W+ P C+ + C K + G P Y N +K + G
Sbjct: 194 DDGFWSKEKPKCVEISC-------KSPDVINGSPISQKIIYKENERFQYKCNM--GYEYS 244
Query: 1939 VQVVSFATEHNWDSLDFYDGGDNNAPRL--GSYSGTTIPHLLNSTSNNLYLNFQSDISVS 1996
+ + TE W L + + P + G YS I H T + + ++ +
Sbjct: 245 ERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKH---RTGDEITYQCRNGFYPA 301
Query: 1997 AAGFHLEYTAIG--------LDSCPEPQTPSSGIKIGDR------YMVGDVVSFQCDQGY 2042
G + T+ G L C P G+ + VG S+ CD+ +
Sbjct: 302 TRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHF 361
Query: 2043 SLQGHS---HITCMPGPVRRWNYPIPICLAQC 2071
S HI C W+ +P CL +C
Sbjct: 362 ETPSGSYWDHIHCTQD---GWSPAVP-CLRKC 389
Score = 32.3 bits (72), Expect = 8.9
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Query: 1676 DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
+Y G V + C++GY ++G + C DDG W++ P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHC--SDDG--FWSKEKPKC 205
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 128 bits (322), Expect = 9e-29
Identities = 119/440 (27%), Positives = 186/440 (42%), Gaps = 68/440 (15%)
Query: 2242 LCGGNITAMN--------GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2293
LCG T + G + SPG+P EY N Q+ W + PPG + + FT E
Sbjct: 10 LCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELS 69
Query: 2294 ----YDFITVWDGPDQNSPQIGQFSGNT----ALESVYSTSNQILIKFHSDFTTSGFFV- 2344
YDF+ + G + GQ S +T ++ YS + + I F SD++ F
Sbjct: 70 HLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTG 129
Query: 2345 --LSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGER 2402
Y A + CQ P E T D + C +G +CR G
Sbjct: 130 FEAFYAAEDIDECQVAP----GEAPTCD----------HHC---HNHLGGFYCSCRAGYV 172
Query: 2403 LQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVE 2461
L + C LC + ++ +G + SP YP YP L C +SIS+E+G+++ + FVE
Sbjct: 173 LHRNKR--TCSALC-SGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVE 229
Query: 2462 FFQTEKEFDVLQVYDGPNIQSPVLISLSGDY---SSAFNITSNGHEVFLQWSADHGNNKK 2518
F E + L YD IQ+ G + + I + + V + + D +
Sbjct: 230 SFDVETHPETLCPYDFLKIQTD--REEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHT 287
Query: 2519 GFRIRY--IAFYCSTPESPPHGYIIS-QTGGQLNSVVRWACDRGFRL------VGKSSAV 2569
G++I Y A C P +PP+G++ Q L C+ G+ L + +AV
Sbjct: 288 GWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAV 347
Query: 2570 CRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVT-------YFCNDGY 2622
C+K +WD P+PAC + CG P +G + +Y+ G VT Y C + +
Sbjct: 348 CQKDG----SWDRPMPACSIVDCGPPDDLPSGRV---EYITGPGVTTYKAVIQYSCEETF 400
Query: 2623 RLSSKELTTAVCQSDGTWSN 2642
VC++DG W++
Sbjct: 401 YTMKVNDGKYVCEADGFWTS 420
Score = 106 bits (265), Expect = 4e-22
Identities = 100/366 (27%), Positives = 157/366 (42%), Gaps = 52/366 (14%)
Query: 1384 GRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASH----DILRVWDGPPEND 1439
GR+ SPG+P Y N+ W + PG + L F FD E SH D +++ G
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1440 MLLKEISGSLI----PEGIHSTLNIVTIQFDTDFYISK--SGFAIQFSSSVATACR-DPG 1492
L + S + +S + + I F +D+ K +GF +++ C+ PG
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 1493 VPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNL 1552
+ G C GY L +R C A C G +
Sbjct: 148 EAPTCDHHCHNHLGG--FYCSCRAGYVLHRNKR-----------------TCSALCSGQV 188
Query: 1553 -TGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFI-SFSIEPN------YDFLYI 1604
T SG + SP +P PYP C ++I++ + + L F+ SF +E + YDFL I
Sbjct: 189 FTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI 248
Query: 1605 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1664
+ + P G LP RIE+ SNT+ + F +D S +TG+ + Y + C P
Sbjct: 249 QTDREEHGPFCG----KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY-TSTAQPCPYP 303
Query: 1665 GNIMNG--TRLGMDYKLGSTVTYYCDAGY-VLQGY---STLTCIMGDDGRPGWNRALPSC 1718
NG + + Y L + + +C+ GY +LQG+ + T + DG W+R +P+C
Sbjct: 304 MAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDG--SWDRPMPAC 361
Query: 1719 H-APCG 1723
CG
Sbjct: 362 SIVDCG 367
Score = 103 bits (257), Expect = 3e-21
Identities = 103/377 (27%), Positives = 155/377 (41%), Gaps = 55/377 (14%)
Query: 690 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 745
G + SP +P Y N+ WT+ + PG R+ L F FDLE ++DF+ + G +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
Query: 746 PILGTFTGAE------VPSHLT--SNSHILRLEFQADHSMSG--RGFNITYNTFGHNECP 795
+L T G E P T S L + F++D+S GF Y +EC
Sbjct: 84 KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
Query: 796 -DPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAP 854
PG N G S C G++ + T C A
Sbjct: 144 VAPGEAPTCDHHCHNHLGGFYCS--CRAGYVLHRNKRT------------------CSAL 183
Query: 855 CGGH-FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITF-ERFQTELNYDVLEVH 912
C G F+ SG + SP +P Y +C + I E G S+ + F E F E + + L +
Sbjct: 184 CSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPY 243
Query: 913 DGPNLLSPL--LGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 970
D + + G + G +P + + SN + + F TD S + G+KIHY T C
Sbjct: 244 DFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHY---TSTAQPC 300
Query: 971 LDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEE-PL-----LCEKNHWWSHPLPT 1022
P P +G + + + S C++GY L PL +C+K+ W P+P
Sbjct: 301 PYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPA 360
Query: 1023 CDAL-CGGDVRGPSGTI 1038
C + CG PSG +
Sbjct: 361 CSIVDCGPPDDLPSGRV 377
Score = 100 bits (250), Expect = 2e-20
Identities = 93/381 (24%), Positives = 153/381 (40%), Gaps = 51/381 (13%)
Query: 2080 GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH----DYLEVRSGSSETS 2135
G + SPGFPG Y + + WT+ P G+ + L F +F E H D++++ SG+ +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 2136 TVIGRLS--GPQIP--SSLFSTTHETSLYFHSDYSQNK--QGFHIVYQAYQLQSC---PD 2186
T+ G+ S + P + +S + F SDYS K GF Y A + C P
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 2187 PRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGN 2246
P T C + +G +C G + N C ALC G
Sbjct: 148 EAP---------------TCDHHC---HNHLGGFYCSCRAGYVLHRNK--RTCSALCSGQ 187
Query: 2247 I-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV---LQTEP----IYDFIT 2298
+ T +G + SP YP YP C + + + G + ++F ++T P YDF+
Sbjct: 188 VFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLK 247
Query: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPP 2358
+ +++ P F G T + + SN + I F +D + ++ + C P
Sbjct: 248 IQTDREEHGP----FCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYP 303
Query: 2359 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA----PPVCQV 2414
PN + ++ + D C G+ L+ + Q DG+ P C +
Sbjct: 304 MAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSI 363
Query: 2415 L-C-PANELRLDSTGVILSPG 2433
+ C P ++L I PG
Sbjct: 364 VDCGPPDDLPSGRVEYITGPG 384
Score = 100 bits (248), Expect = 3e-20
Identities = 100/383 (26%), Positives = 166/383 (43%), Gaps = 57/383 (14%)
Query: 851 CGA---PCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN- 905
CG+ P G + P G + SPG+PG Y + W + A PG+ +++ F F EL+
Sbjct: 11 CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
Query: 906 ---YDVLEVHDGPNLLSPLLG--SYNGTQVP--QFLFSSSNFIYLLFTTD--NSRSNNGF 956
YD +++ G +L+ L G S + + P +S + + + F +D N + GF
Sbjct: 71 LCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGF 130
Query: 957 KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 1016
+ Y + ++ + PG + H+ G SC +GY L +
Sbjct: 131 EAFYAAEDIDECQ-VAPGEAPTCDHHCHNHLGG--FYCSCRAGYVLHRNK---------- 177
Query: 1017 SHPLPTCDALCGGDV-RGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF-HTFHL 1074
TC ALC G V SG + SP YP YP +CT+++ + G V +F +F +
Sbjct: 178 ----RTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDV 233
Query: 1075 EDH------HDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1128
E H +D+L I + P G LP I + + F++D S +
Sbjct: 234 ETHPETLCPYDFLKIQTDREEHGPFC---GKTLPHRIET---KSNTVTITFVTDESGDHT 287
Query: 1129 GFNITFSEYNLEPCEDPGIPQYG--SRIGFNFGIGDTLTFSCSSGYR-LEG-----TSEI 1180
G+ I ++ +PC P P G S + + + D+ + C +GY L+G +
Sbjct: 288 GWKIHYTS-TAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTA 346
Query: 1181 ICLGGGRRVWSAPLPRC-VAECG 1202
+C G W P+P C + +CG
Sbjct: 347 VCQKDGS--WDRPMPACSIVDCG 367
Score = 98.2 bits (243), Expect = 1e-19
Identities = 95/368 (25%), Positives = 150/368 (40%), Gaps = 54/368 (14%)
Query: 1731 GTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS--LL 1788
G + SP +P Y+ +++ P + + F F L + E YD S +L
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCE-YDFVKLSSGAKVL 86
Query: 1789 SSLSGSHSGES---------LPLSSGNQITIR--FTSVGPITAKGFHFVYQAVPRTSSTQ 1837
++L G S ++ L S IT R +++ P T GF Y A +
Sbjct: 87 ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFT--GFEAFYAA---EDIDE 141
Query: 1838 CSSVP--EPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1895
C P P N C GY+LH + TC
Sbjct: 142 CQVAPGEAPTCDHHCHNHLG---GFYCSCRAGYVLHRNKR------------------TC 180
Query: 1896 IVPCGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSL 1953
C G + T+R G + SP YP PY +C + I++ EG + + V SF E + ++L
Sbjct: 181 SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETL 240
Query: 1954 DFYD--GGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDS 2011
YD + G + G T+PH + + SN + + F +D S G+ + YT+
Sbjct: 241 CPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTA-QP 299
Query: 2012 CPEPQTPSSG--IKIGDRYMVGDVVSFQCDQGYS-LQGHSHITCMPGPVRR---WNYPIP 2065
CP P P +G + +Y++ D S C+ GY LQGH + ++ W+ P+P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2066 IC-LAQCG 2072
C + CG
Sbjct: 360 ACSIVDCG 367
Score = 92.0 bits (227), Expect = 9e-18
Identities = 96/362 (26%), Positives = 150/362 (41%), Gaps = 47/362 (12%)
Query: 1908 GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNA 1963
G + SPG+P Y N+ W +T P G +++ F E + +D + G A
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1964 PRLGSYSGTTI----PHLLNSTSNNLYLNFQSDISVSA--AGFHLEYTAIGLDSCPEPQT 2017
G S T S ++L + F+SD S GF Y A +D C Q
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC---QV 144
Query: 2018 PSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM-S 2076
D + + F C +C G V N C A C G + +
Sbjct: 145 APGEAPTCDHHCHNHLGGFYC------------SCRAGYVLHRNKRT--CSALCSGQVFT 190
Query: 2077 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFV-NFSTET------IHDYLEVRS 2129
SG + SP +P YP CT++I+L GF V L FV +F ET +D+L++++
Sbjct: 191 QRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQT 250
Query: 2130 GSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2189
E G G +P + + ++ ++ F +D S + G+ I Y + Q CP P
Sbjct: 251 DREEH----GPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTS-TAQPCPYPMA 305
Query: 2190 FRNGFV--IGNDFTVGQTISFECFPGYTLI-GNSALTCLHGVSR---NWNHPLPRCEAL- 2242
NG V + + + + S C GY L+ G+ L V + +W+ P+P C +
Sbjct: 306 PPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVD 365
Query: 2243 CG 2244
CG
Sbjct: 366 CG 367
Score = 86.3 bits (212), Expect = 5e-16
Identities = 96/365 (26%), Positives = 148/365 (40%), Gaps = 50/365 (13%)
Query: 1210 GILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF-----HLAQGDVLKIYDGKDKTT 1264
G L SP +P Y N+ E +++ G + + F HL + D +K+ G
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1265 HLLGAFTGASMRGL---TLSSTSNQLWLEFNSD--TEGTDEGFQLVYTSFELSHCE-DPG 1318
L G + + R T S + L + F SD E GF+ Y + ++ C+ PG
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 1319 -IPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1377
P + + H G C GY LH + +C A C G+
Sbjct: 148 EAPTCDHHCHN--HLGG--FYCSCRAGYVLHRNKR----------------TCSALCSGQ 187
Query: 1378 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFL-AFDTE------ASHDILR 1430
+ SG + SP YP PY C + I ++ G V L F+ +FD E +D L+
Sbjct: 188 VFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLK 247
Query: 1431 VWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRD 1490
+ E+ G +P I + N VTI F TD +G+ I ++S+ A C
Sbjct: 248 IQTDREEHG----PFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTST-AQPCPY 302
Query: 1491 PGVPMNGTRNGDGRE--PGDTVVFQCDPGYE-LQGE---ERITCIQVENRYFWQPSPPVC 1544
P P NG + + D+ C+ GYE LQG + T + ++ + +P P
Sbjct: 303 PMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACS 362
Query: 1545 IAPCG 1549
I CG
Sbjct: 363 IVDCG 367
Score = 79.0 bits (193), Expect = 8e-14
Identities = 98/388 (25%), Positives = 149/388 (38%), Gaps = 57/388 (14%)
Query: 517 GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG----YDTLTIGDGGEV- 571
G SP FP +Y ++ + W +TA + +++ F FDLE+ YD + + G +V
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYR-LRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
Query: 572 ----GDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGS--VGFKVNYKEIEKESCG 625
G T + G D S+ S + + ++D S GF+ Y + + C
Sbjct: 87 ATLCGQESTDTERAPGK---DTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
Query: 626 -DPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 684
PG D + + F C C+ N C C
Sbjct: 144 VAPGE----APTCDHHCHNHLGGFYCS------------CRAGYVLHRNKRTCSALCSGQ 187
Query: 685 -FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSF-NDFDLESQ------FDFLA 736
FT G + SP+YP Y +C ++I + G + L F FD+E+ +DFL
Sbjct: 188 VFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLK 247
Query: 737 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPD 796
++ P F G +P + + S+ + + F D S G+ I Y T CP
Sbjct: 248 IQTDREEHGP----FCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHY-TSTAQPCPY 302
Query: 797 PGIPINAR--RFGDNFQLGSSISVICEEGFIKTQG---TETITCILM-DGKVMWSGLIPK 850
P P N + L S S+ CE G+ QG ++ T + DG W +P
Sbjct: 303 PMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGS--WDRPMPA 360
Query: 851 CG-APCGGHFSAPSG---VILSPGWPGY 874
C CG PSG I PG Y
Sbjct: 361 CSIVDCGPPDDLPSGRVEYITGPGVTTY 388
Score = 79.0 bits (193), Expect = 8e-14
Identities = 101/372 (27%), Positives = 152/372 (40%), Gaps = 60/372 (16%)
Query: 1557 GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNS 1612
G + SP FP Y + ++ WT+T Y + L F F +E + YDF+ + G +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1613 PLIGSFQDSKLPERIE------SSSNTMHLAFRSDGSVS--YTGFHLEYKAKLRESCFDP 1664
L G Q+S ER S +++ + FRSD S +TGF Y A+ + C
Sbjct: 88 TLCG--QESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC--- 142
Query: 1665 GNIMNGTRLGMDYKLGSTVT-YYCD--AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1721
+ G D+ + + +YC AGYVL +R +C A
Sbjct: 143 -QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVL------------------HRNKRTCSAL 183
Query: 1722 C-GSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV-FFQTSLH-DVVEVY 1778
C G T G + SP YP+ Y +C YSI++ + F V FV F H + + Y
Sbjct: 184 CSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPY 243
Query: 1779 DGPTQQSSLLSSLSGSHSGESLP---LSSGNQITIRFTS--VGPITAKGFHFVYQAVPRT 1833
D Q+ G G++LP + N +TI F + G T H+ A P
Sbjct: 244 DFLKIQTD--REEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQP-- 299
Query: 1834 SSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGY-ILHGSIAIRCET-VPNSLAQWN 1889
C P G + ++ + S C GY +L G + ++ T V W+
Sbjct: 300 ----CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWD 355
Query: 1890 DSLPTC-IVPCG 1900
+P C IV CG
Sbjct: 356 RPMPACSIVDCG 367
Score = 77.8 bits (190), Expect = 2e-13
Identities = 97/368 (26%), Positives = 144/368 (39%), Gaps = 56/368 (15%)
Query: 1036 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHH----DYLLITENGSFTQ 1091
G + SPG+P Y N WT+ G ++ F F LE H D++ ++ S +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS---SGAK 84
Query: 1092 PLARLTGSDLPPTINAGLYGNFRA-----QLRFISDFSIS--YEGFNITFSEYNLEPCE- 1143
LA L G + T A F + + F SD+S + GF ++ +++ C+
Sbjct: 85 VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQV 144
Query: 1144 DPG-IPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC- 1201
PG P + G SC +GY L C A C
Sbjct: 145 APGEAPTCDHHCHNHLG---GFYCSCRAGYVLHRNKRT----------------CSALCS 185
Query: 1202 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAG--------KGINISARTFHLAQGDV 1253
G T G L SP YP Y C YSI ++ G + ++ L D
Sbjct: 186 GQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDF 245
Query: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
LKI D+ H G F G ++ + + SN + + F +D G G+++ YTS
Sbjct: 246 LKIQ--TDREEH--GPFCGKTLPH-RIETKSNTVTITFVTDESGDHTGWKIHYTS-TAQP 299
Query: 1314 CEDPGIPQFGYKISDQG-HFAGSTIIYGCNPGY-TLHGSSLLKCMTG---ERRAWDYPLP 1368
C P P G+ Q + + C GY L G LK T + +WD P+P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 1369 SC-IAECG 1375
+C I +CG
Sbjct: 360 ACSIVDCG 367
Score = 64.3 bits (155), Expect = 2e-09
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 39/291 (13%)
Query: 34 GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLSLYDGHPH-P 88
G + SPGFP Y N W + A R+++ F F LE EYD++ L G
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 89 TNFRTRLTGFHLPP---PVTSTKSVFSLRLTSDFAVSAH--GFKVYYEELQSSSCG-NPG 142
T T P S S + SD++ GF+ +Y C PG
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 143 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
P + G SC GY+L + + TC A +C G
Sbjct: 148 EAPTCDHHCHNHLGG--FYCSCRAGYVLHRNKR-TCSA-------------LCS-----G 186
Query: 203 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTD-FQMEE------KYDYL 255
SG +SSP +P Y + CT++I E G ++ L F + F +E YD+L
Sbjct: 187 QVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFL 246
Query: 256 EIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSS 306
+I+ G +P I + N + + FVTD + + G+ Y ++
Sbjct: 247 KIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTA 297
Score = 63.5 bits (153), Expect = 4e-09
Identities = 85/340 (25%), Positives = 130/340 (38%), Gaps = 47/340 (13%)
Query: 33 NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVF-QSFALEEEYDYLSLYDGHPHPTNF 91
+G + SP +P YP ++CT+ I EE + + F +SF +E + L YD T+
Sbjct: 193 SGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDR 252
Query: 92 RTR--LTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVL 149
G LP + + + ++ +D + G+K++Y + C P PP G +
Sbjct: 253 EEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTS-TAQPCPYPMAPPNGHV 311
Query: 150 --YGTRFDVGDKIRYSCVTGY-ILDGH-PQLTCIANSVNTASWDFPVPICRAEDACGGTM 205
++ + D C TGY +L GH P + A SWD P+P C D CG
Sbjct: 312 SPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVD-CGPPD 370
Query: 206 RGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS----E 261
SG + EY + PG T + EE + +++ E
Sbjct: 371 DLPSGRV-------EY----------ITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCE 413
Query: 262 PPTIWLS-----GMNIPPPIISNKNWLRLHFVTDSNHRYRGFSA-----PYQGSSTLTHT 311
W S + + P+ L T Y G A P+Q L T
Sbjct: 414 ADGFWTSSKGEKSLPVCEPVCG------LSARTTGGRIYGGQKAKPGDFPWQ-VLILGGT 466
Query: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLS 351
T+ G L N T A AV D + + T+ RLS
Sbjct: 467 TAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLS 506
Score = 60.5 bits (145), Expect = 3e-08
Identities = 59/203 (29%), Positives = 80/203 (39%), Gaps = 38/203 (18%)
Query: 3009 SGDATG----------TCGDPGTP--GHGSRQESNFRTKSTVRYACDTGY-ILHG----- 3050
SGD TG C P P GH S ++ + K + C+TGY +L G
Sbjct: 283 SGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLK 342
Query: 3051 SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG---TTFSSSVIYSCMEGY-- 3105
S C +GSW P C V CG P +G+V I G TT+ + + YSC E +
Sbjct: 343 SFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYT 402
Query: 3106 --ILSGPSVRQCTANGTWSG-----TLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYM 3158
+ G V C A+G W+ +LP C + CG G YG GQ
Sbjct: 403 MKVNDGKYV--CEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGRIYG-----GQKAKPG 454
Query: 3159 CQPGYTMELNGSRIRTCTINGTW 3181
P + L G+ + W
Sbjct: 455 DFPWQVLILGGTTAAGALLYDNW 477
Score = 57.8 bits (138), Expect = 2e-07
Identities = 59/251 (23%), Positives = 93/251 (37%), Gaps = 27/251 (10%)
Query: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 558
++ C G SG +SP +P Y + C + I+ VI E FD+E
Sbjct: 176 NKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVET 235
Query: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
+TL D ++ R G +P I + S+ + + TDES G+K++Y
Sbjct: 236 HPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTS 295
Query: 619 IEKESCGDPGTPLYG--IREGDGFSNRDVLRFECQFGFEL------IGEKSIVCQENNQW 670
+ C P P G + +D C+ G+EL + + VCQ++ W
Sbjct: 296 -TAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSW 354
Query: 671 SANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE 729
+P C I C P G V I+ PG + + + E
Sbjct: 355 DRPMPACSIVDCGPPDDLPSGRV-----------------EYITGPGVTTYKAVIQYSCE 397
Query: 730 SQFDFLAVKDG 740
F + V DG
Sbjct: 398 ETFYTMKVNDG 408
Score = 53.9 bits (128), Expect = 3e-06
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 16/137 (11%)
Query: 2835 CGHPGSPIYGRTSGNGFNF--NDVVTFSCNIGY-LMQG--PTK---AQCQANRQWSHPPP 2886
C +P +P G S + D + C GY L+QG P K A CQ + W P P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2887 MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF--GSSVLICQPNGQW- 2943
C +V+C P + + E G TY V+ Y C ++ +C+ +G W
Sbjct: 360 ACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWT 419
Query: 2944 ----DKPLPECIMIDCG 2956
+K LP C + CG
Sbjct: 420 SSKGEKSLPVCEPV-CG 435
Score = 53.5 bits (127), Expect = 4e-06
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 2921 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA----VLSGEKYTFGST 2976
Y+ G+ S +CQ +G WD+P+P C ++DCG P P+ + T+ +
Sbjct: 332 YELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAV 391
Query: 2977 VHYSC--TGKRSLLGQSSRTCQLNGHWSGSQ 3005
+ YSC T + C+ +G W+ S+
Sbjct: 392 IQYSCEETFYTMKVNDGKYVCEADGFWTSSK 422
Score = 50.8 bits (120), Expect = 2e-05
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 23/158 (14%)
Query: 3187 TCRAVTCPTPPQISNGRLEGTNFDWGF--SISYICSPGYEL--------SFPAVLTCVGN 3236
T A CP P NG + + S S C GYEL SF AV C +
Sbjct: 294 TSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAV--CQKD 351
Query: 3237 GTWSGEVPQCLPKFCGDPGIPAQGKREGKS----FIYQSEVSFSCNFPF--ILVGSSTRI 3290
G+W +P C CG P G+ E + Y++ + +SC F + V +
Sbjct: 352 GSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYV 411
Query: 3291 CQADGTWSGSS-----PHCIEPTQTSCENPGVPRHGSQ 3323
C+ADG W+ S P C S G +G Q
Sbjct: 412 CEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQ 449
Score = 48.5 bits (114), Expect = 1e-04
Identities = 38/157 (24%), Positives = 65/157 (41%), Gaps = 27/157 (17%)
Query: 3071 AVQCGNPGTTANGKVFRI-------DGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSG 3123
A C P NG V + D + Y ++G++ C +G+W
Sbjct: 297 AQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDR 356
Query: 3124 TLPNCTIISCGDP-GIPANGLRYGDDYVVGQNVS-------YMCQPG-YTMELNGSRIRT 3174
+P C+I+ CG P +P+ + +Y+ G V+ Y C+ YTM++N +
Sbjct: 357 PMPACSIVDCGPPDDLPSGRV----EYITGPGVTTYKAVIQYSCEETFYTMKVNDGKY-V 411
Query: 3175 CTINGTWSG-----VMPTCRAVTCPTPPQISNGRLEG 3206
C +G W+ +P C V C + + GR+ G
Sbjct: 412 CEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGRIYG 447
Score = 43.9 bits (102), Expect = 0.003
Identities = 90/430 (20%), Positives = 148/430 (34%), Gaps = 76/430 (17%)
Query: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQS 2482
G + SPG+P Y N Q W+++ GY + ++ F E E+D +++ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 2483 PVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNKK--GFRIRYIAFYCSTPESPP- 2536
+ S D A S G + + + +D+ N K GF Y A + P
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 2537 -----HGYIISQTGGQLNSVVRWACDRGFRLVGKS---SAVCRKSSYGYHAWDA-----P 2583
+ + GG S C G+ L SA+C + + + P
Sbjct: 148 EAPTCDHHCHNHLGGFYCS-----CRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYP 202
Query: 2584 VPACQAISCGIPKAPTNGGILTTDYL----VGTRVTYFCNDGYRL--SSKELTTAVCQSD 2637
P + SC + G + D++ V T C + + +E C
Sbjct: 203 RPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFC--- 259
Query: 2638 GTWSNHNKTPRCVVVTCPSINSFILEHGRWRI-------------------VNGSHYEYK 2678
G H + VT + +H W+I V+ +Y
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYI 319
Query: 2679 TKVVFS--CDPGYH------GLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNK 2730
K FS C+ GY L + C +G SW P C I+ CG P+G
Sbjct: 320 LKDSFSIFCETGYELLQGHLPLKSFTAVCQKDG--SWDRPMPACSIVDCGPPDDLPSGRV 377
Query: 2731 IGTQ----TSYGSTAIFTCDLGF--MLVGSAVRECLSSGLWSESETR----CLAGHCGIP 2780
T+Y + ++C+ F M V C + G W+ S+ CG+
Sbjct: 378 EYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLS 437
Query: 2781 ELIVNGQVIG 2790
G++ G
Sbjct: 438 ARTTGGRIYG 447
Score = 43.5 bits (101), Expect = 0.004
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 19/134 (14%)
Query: 2777 CGIPELIVNGQV--IGENYGYRDTVVYQCNPGFRLIG------SSVRICQQDHNWSGQLP 2828
C P NG V + Y +D+ C G+ L+ S +CQ+D +W +P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2829 SCVPVSCGHPGSPIYGRT---SGNGF-NFNDVVTFSCNIGY--LMQGPTKAQCQANRQWS 2882
+C V CG P GR +G G + V+ +SC + + K C+A+ W+
Sbjct: 360 ACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWT 419
Query: 2883 HPP-----PMCKVV 2891
P+C+ V
Sbjct: 420 SSKGEKSLPVCEPV 433
Score = 43.1 bits (100), Expect = 0.005
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 23/151 (15%)
Query: 2955 CGHPGVPPNAVLSG--EKYTFGSTVHYSC-TGKRSLLGQS-----SRTCQLNGHWSGSQP 3006
C +P PPN +S KY + C TG L G + CQ +G W P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 3007 HCSGDATGTCGDPGTPGHGSRQ----ESNFRTKSTVRYAC-DTGYILHGSEER-TCLANG 3060
CS CG P G + K+ ++Y+C +T Y + ++ + C A+G
Sbjct: 360 ACS---IVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 416
Query: 3061 SWTGRQ-----PECKAVQCGNPGTTANGKVF 3086
WT + P C+ V CG T G+++
Sbjct: 417 FWTSSKGEKSLPVCEPV-CGLSARTTGGRIY 446
Score = 40.0 bits (92), Expect = 0.043
Identities = 26/108 (24%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 3329 FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANV---VGM 3385
F + + +GHL S T C D +W P C C P+ V G
Sbjct: 324 FSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGP 383
Query: 3386 DLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNTWTG-----KVPICE 3427
+ ++ + Y+C+ F+ + + VC +D WT +P+CE
Sbjct: 384 GVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCE 431
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 125 bits (313), Expect = 1e-27
Identities = 93/302 (30%), Positives = 133/302 (44%), Gaps = 40/302 (13%)
Query: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSL-DFYD 1957
CGG+L+ +G SP YP+PY N +CVW I V IQ+++ + + E L D +
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 1958 GGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI--GLDSCPEP 2015
L G P LN+ +++L + F SD SV GFH Y A+ G SC
Sbjct: 204 LSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSCAHD 263
Query: 2016 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS----HITCMPGPVRRWNYPIPICLAQ- 2070
+ F+CDQ L S C G C A+
Sbjct: 264 E-------------------FRCDQLICLLPDSVCDGFANCADGSDET------NCSAKF 298
Query: 2071 --CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
CGG ++ G +P + YP L CTW I++P G + LQF NFS E DY
Sbjct: 299 SGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDY 358
Query: 2125 LEV-RSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2183
+EV + SS +++GR G + P L S+ HE ++ F +D+ + GF Y A+
Sbjct: 359 VEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATE 418
Query: 2184 CP 2185
P
Sbjct: 419 NP 420
Score = 117 bits (293), Expect = 2e-25
Identities = 95/306 (31%), Positives = 131/306 (42%), Gaps = 45/306 (14%)
Query: 507 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 562
TCG L GP G F+SPN+P Y N CVW I V T+ IQ+ E +E +D
Sbjct: 143 TCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHI-QVATDHAIQLKIEALSIESVASCLFDR 201
Query: 563 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE-- 620
L + +P L + G P + + +S + + +D SV GF Y+ +
Sbjct: 202 LELSP-----EPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 256
Query: 621 KESCG------DPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANI 674
+ SC D L DGF+N C G + N
Sbjct: 257 RGSCAHDEFRCDQLICLLPDSVCDGFAN-------CADGSD---------------ETNC 294
Query: 675 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ--- 731
C N T GT +P Y + Y + L C W I G I L F++F LE+Q
Sbjct: 295 SAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDEC 354
Query: 732 -FDFLAVKDGDSPES-PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTF 789
FD++ V + S + +LG F GAE P HL S+ H L + F+ DH +S GF+ TY F
Sbjct: 355 KFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAF 414
Query: 790 GHNECP 795
E P
Sbjct: 415 NATENP 420
Score = 108 bits (271), Expect = 7e-23
Identities = 98/349 (28%), Positives = 147/349 (42%), Gaps = 45/349 (12%)
Query: 813 GSSISVICEEGFIKTQGTETITCILMDGKVMW---SGLIPKCGAPCGGHFSAPSGVILSP 869
G+S S + G T T TIT G SG+ P + CGG S P G SP
Sbjct: 99 GASHSPLPAGGLTTTTTTPTITTSQAAGTPKGQQESGVSPSPQSTCGGLLSGPRGFFSSP 158
Query: 870 GWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSY 925
+P Y + +C W I+ H+I++ E E +D LE+ P PLL
Sbjct: 159 NYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLELSPEPE--GPLL-RV 215
Query: 926 NGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD 985
G P L ++++ + ++F +D+S GF Y+++ SC HD
Sbjct: 216 CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSC------------AHD 263
Query: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL---CGGDVRGPSGTILSPG 1042
F CD L + N C A CGG++ G GT +P
Sbjct: 264 -------EFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPS 316
Query: 1043 YPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITE---NGSFTQPLAR 1095
Y + YP+ L CTW + V G ++ FH F LE DY+ + E +G+F+ L R
Sbjct: 317 YLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSL-LGR 375
Query: 1096 LTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNL--EPC 1142
G++ PP + + + + F +D IS GF+ T+ +N PC
Sbjct: 376 FCGAEPPPHL---VSSHHELAVLFRTDHGISSGGFSATYLAFNATENPC 421
Score = 99.8 bits (247), Expect = 5e-20
Identities = 84/308 (27%), Positives = 125/308 (40%), Gaps = 38/308 (12%)
Query: 24 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 79
TCGG L G G SP +P YP +C W I + IQ+ ++ ++E +D L
Sbjct: 143 TCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRL 202
Query: 80 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
L P P R+ G PP + + S + SD +V GF +Y+ +
Sbjct: 203 EL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAM------ 253
Query: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE- 198
P +G F I + + DG ++ N C A+
Sbjct: 254 ---APGRGSCAHDEFRCDQLI--CLLPDSVCDGFANCADGSDETN----------CSAKF 298
Query: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 254
CGG + G G S+PS+ +Y + CTW I G +I L F +F +E K+DY
Sbjct: 299 SGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDY 358
Query: 255 LEI-EGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
+E+ E S L G PP ++S+ + L + F TD GFSA Y +
Sbjct: 359 VEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATE 418
Query: 310 HTTSTGEL 317
+ EL
Sbjct: 419 NPCGPSEL 426
Score = 99.0 bits (245), Expect = 8e-20
Identities = 84/305 (27%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 681 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLA 736
C + P G SP+YP+ Y N +C+W I I L +ES FD L
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 737 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTF--GHNEC 794
+ PE P+L P+ T+ SH+L + F +D S+ G GF+ Y G C
Sbjct: 204 L--SPEPEGPLLRVCGRVPPPTLNTNASHLL-VVFVSDSSVEGFGFHAWYQAMAPGRGSC 260
Query: 795 PDPGIPINARRFGDNFQLGSSISVICE---EGFIK-TQGTETITCILMDGKVMWSGLIPK 850
D F+ I ++ + +GF G++ C +SG
Sbjct: 261 AH-----------DEFRCDQLICLLPDSVCDGFANCADGSDETNC-----SAKFSG---- 300
Query: 851 CGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNY 906
CGG+ + G +P + Y L C W I GHSI++ F F Q E +
Sbjct: 301 ----CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKF 356
Query: 907 DVLEVHD-GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTV 965
D +EV++ + LLG + G + P L SS + + +LF TD+ S+ GF Y +
Sbjct: 357 DYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNA 416
Query: 966 NTYSC 970
C
Sbjct: 417 TENPC 421
Score = 93.6 bits (231), Expect = 3e-18
Identities = 90/310 (29%), Positives = 134/310 (43%), Gaps = 41/310 (13%)
Query: 1539 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN 1598
PSP + CGG L+G GF SPN+P PYP + C W I V D+ I L + SIE
Sbjct: 138 PSPQ---STCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESV 194
Query: 1599 YDFLY--IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1656
L+ + P+ PL+ P + ++++ + + F SD SV GFH Y+A
Sbjct: 195 ASCLFDRLELSPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQA- 252
Query: 1657 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
PG G+ +++ + D+ V G++ C G D
Sbjct: 253 -----MAPG---RGSCAHDEFRCDQLICLLPDS--VCDGFA--NCADGSDE--------T 292
Query: 1717 SCHAP---CGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLH- 1772
+C A CG TG +GT +P+Y + Y C + I+VP + QF F
Sbjct: 293 NCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQD 352
Query: 1773 ----DVVEVYDGPTQQSSLLSSLSGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHF 1825
D VEVY+ SS SL G G P +SS +++ + F + I++ GF
Sbjct: 353 ECKFDYVEVYE---TSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSA 409
Query: 1826 VYQAVPRTSS 1835
Y A T +
Sbjct: 410 TYLAFNATEN 419
Score = 89.4 bits (220), Expect = 6e-17
Identities = 90/334 (26%), Positives = 138/334 (41%), Gaps = 43/334 (12%)
Query: 2237 PRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD- 2295
P ++ CGG ++ G SP YPD YP C W ++V + I + L E +
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASC 197
Query: 2296 -FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRV 2354
F + P+ P + + G ++ + ++ +L+ F SD + GF +HA+
Sbjct: 198 LFDRLELSPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGF---GFHAWY--- 250
Query: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV-CQ 2413
Q P + DEF +I LP G A C DG+ C
Sbjct: 251 -QAMAPGRGS---CAHDEFRCDQLICL--LPDSVCDGFA--NCA-------DGSDETNCS 295
Query: 2414 VL---CPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF----QTE 2466
C N L G +P Y YP+ +C W ISV G++I + F Q E
Sbjct: 296 AKFSGCGGNLTGLQ--GTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDE 353
Query: 2467 KEFDVLQVYDGPNIQSPVLISLSGDYSSAF---NITSNGHEVFLQWSADHGNNKKGFRIR 2523
+FD ++VY+ S SL G + A ++ S+ HE+ + + DHG + GF
Sbjct: 354 CKFDYVEVYE---TSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSAT 410
Query: 2524 YIAFYCSTPESPPHGYIISQTGGQLNSVVRWACD 2557
Y+AF + P + Q GG V+W CD
Sbjct: 411 YLAFNATENPCGP-SELSCQAGGCKG--VQWMCD 441
Score = 77.8 bits (190), Expect = 2e-13
Identities = 74/300 (24%), Positives = 115/300 (38%), Gaps = 34/300 (11%)
Query: 1021 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1080
P+ + CGG + GP G SP YP+ YP + +C W + V +Q +E
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASC 197
Query: 1081 LL--ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
L + + PL R+ G PPT+N + F+SD S+ GF+ +
Sbjct: 198 LFDRLELSPEPEGPLLRVCGRVPPPTLNTNA---SHLLVVFVSDSSVEGFGFHAWYQAM- 253
Query: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
P GS F + S +C G + C
Sbjct: 254 --------APGRGSCAHDEFRCDQLICLLPDS----------VCDGFANCADGSDETNCS 295
Query: 1199 AE---CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQ 1250
A+ CG + T +G +P+Y Y + C + I V AG I + F L +
Sbjct: 296 AKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECK 355
Query: 1251 GDVLKIYD-GKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSF 1309
D +++Y+ LLG F GA L S+ ++L + F +D + GF Y +F
Sbjct: 356 FDYVEVYETSSSGAFSLLGRFCGAEPPP-HLVSSHHELAVLFRTDHGISSGGFSATYLAF 414
Score = 62.0 bits (149), Expect = 1e-08
Identities = 39/136 (28%), Positives = 62/136 (45%), Gaps = 7/136 (5%)
Query: 14 DRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALE 73
D S CGG L GL GT +P + YP+ CTW I + I++ F +F+LE
Sbjct: 290 DETNCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLE 349
Query: 74 EE----YDYLSLYD-GHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV 128
+ +DY+ +Y+ + R G PP + S+ ++ +D +S+ GF
Sbjct: 350 AQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSA 409
Query: 129 YYEELQSSSCGNPGVP 144
Y L ++ NP P
Sbjct: 410 TY--LAFNATENPCGP 423
Score = 61.6 bits (148), Expect = 1e-08
Identities = 74/306 (24%), Positives = 114/306 (37%), Gaps = 40/306 (13%)
Query: 1195 PRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVL 1254
P + CG + G SPNYP Y N C++ IQV I + + +
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSI-ESVAS 196
Query: 1255 KIYDGKDKTTHLLGAFTGASMR--GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELS 1312
++D + + G R TL++ ++ L + F SD+ GF Y +
Sbjct: 197 CLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMA-- 254
Query: 1313 HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLL----KCMTGERRAWDYPLP 1368
P G D+ + C+ L S+ C G
Sbjct: 255 -------PGRGSCAHDE---------FRCDQLICLLPDSVCDGFANCADGSDET------ 292
Query: 1369 SCIAE---CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA- 1424
+C A+ CGG G G +P Y Y + L C W I V G+ + LQF F EA
Sbjct: 293 NCSAKFSGCGGNLTG-LQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQ 351
Query: 1425 ---SHDILRVWDGPPENDM-LLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1480
D + V++ LL G+ P + S+ + + + F TD IS GF+ +
Sbjct: 352 DECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Query: 1481 SSSVAT 1486
+ AT
Sbjct: 412 LAFNAT 417
Score = 57.8 bits (138), Expect = 2e-07
Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 5/111 (4%)
Query: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
+ CGG + G G SSP++P+ Y N C W I I L +E +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 254 YLEIEGS-EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
LE+ E P + + G PP + +N + L + FV+DS+ GF A YQ
Sbjct: 201 RLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQ 251
Score = 52.4 bits (124), Expect = 8e-06
Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 8/152 (5%)
Query: 469 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQY 528
+F CD+ L C A + K CG NL G GTF++P++ QY
Sbjct: 264 EFRCDQLICL--LPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQQY 321
Query: 529 DSNAQCVWVITAVNTNKVIQINFEEFDL----EIGYDTLTIGDGGEVGDPRTVLQVLTGS 584
C W I +V I++ F F L E +D + + + G ++L G+
Sbjct: 322 PHQLLCTWHI-SVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSG-AFSLLGRFCGA 379
Query: 585 FVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY 616
P +VS ++ + +TD + S GF Y
Sbjct: 380 EPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 36.2 bits (82), Expect = 0.61
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 2404 QMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF 2463
Q G P Q C L G SP YPD YP C W I V + I + +E
Sbjct: 132 QESGVSPSPQSTCGG--LLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEAL 189
Query: 2464 QTEKE----FDVLQVYDGPNIQSPVL 2485
E FD L++ P + P+L
Sbjct: 190 SIESVASCLFDRLEL--SPEPEGPLL 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 170,028,648
Number of Sequences: 37866
Number of extensions: 8921449
Number of successful extensions: 34129
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 17175
Number of HSP's gapped (non-prelim): 6472
length of query: 3667
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3545
effective length of database: 13,627,866
effective search space: 48310784970
effective search space used: 48310784970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.