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Search of human proteins with 38016947
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38016947 complement component 5 preproprotein [Homo sapiens]
(1676 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38016947 complement component 5 preproprotein [Homo sapiens] 3355 0.0
gi|115298678 complement component 3 precursor [Homo sapiens] 675 0.0
gi|169218213 PREDICTED: similar to complement component C3, part... 546 e-155
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s... 517 e-146
gi|178557739 complement component 4B preproprotein [Homo sapiens] 515 e-145
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s... 515 e-145
gi|67190748 complement component 4A preproprotein [Homo sapiens] 513 e-145
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens] 268 3e-71
gi|162809334 pregnancy-zone protein [Homo sapiens] 186 1e-46
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens] 183 1e-45
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens] 183 1e-45
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens] 181 5e-45
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens] 181 7e-45
gi|239758130 PREDICTED: similar to complement component 4B (Chil... 150 1e-35
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 145 2e-34
gi|169214179 PREDICTED: similar to complement component 3 [Homo ... 142 4e-33
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens] 134 7e-31
gi|169204289 PREDICTED: ovostatin [Homo sapiens] 134 7e-31
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg... 105 5e-22
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens] 74 2e-12
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 64 9e-10
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 45 8e-04
gi|34452173 integrin alpha X precursor [Homo sapiens] 36 0.27
gi|95007030 lines homolog 1 [Homo sapiens] 33 1.8
gi|95007028 lines homolog 1 [Homo sapiens] 33 1.8
gi|95007024 lines homolog 1 [Homo sapiens] 33 1.8
gi|95007026 lines homolog 1 [Homo sapiens] 33 1.8
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 33 3.0
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 33 3.0
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 33 3.0
>gi|38016947 complement component 5 preproprotein [Homo sapiens]
Length = 1676
Score = 3355 bits (8699), Expect = 0.0
Identities = 1676/1676 (100%), Positives = 1676/1676 (100%)
Query: 1 MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYP 60
MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYP
Sbjct: 1 MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYP 60
Query: 61 DKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPIT 120
DKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPIT
Sbjct: 61 DKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPIT 120
Query: 121 YDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHI 180
YDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHI
Sbjct: 121 YDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHI 180
Query: 181 GIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGY 240
GIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGY
Sbjct: 181 GIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGY 240
Query: 241 KNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVT 300
KNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVT
Sbjct: 241 KNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVT 300
Query: 301 FDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATP 360
FDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATP
Sbjct: 301 FDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATP 360
Query: 361 LFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASF 420
LFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASF
Sbjct: 361 LFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASF 420
Query: 421 VLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGE 480
VLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGE
Sbjct: 421 VLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGE 480
Query: 481 HLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRL 540
HLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRL
Sbjct: 481 HLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRL 540
Query: 541 LVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSWV 600
LVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSWV
Sbjct: 541 LVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSWV 600
Query: 601 ALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANAD 660
ALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANAD
Sbjct: 601 ALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANAD 660
Query: 661 DSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQRAARISL 720
DSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQRAARISL
Sbjct: 661 DSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQRAARISL 720
Query: 721 GPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLV 780
GPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLV
Sbjct: 721 GPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLV 780
Query: 781 PRRKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQ 840
PRRKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQ
Sbjct: 781 PRRKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQ 840
Query: 841 LKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTV 900
LKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTV
Sbjct: 841 LKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTV 900
Query: 901 LPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFP 960
LPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFP
Sbjct: 901 LPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFP 960
Query: 961 YRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFY 1020
YRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFY
Sbjct: 961 YRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFY 1020
Query: 1021 VFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLTA 1080
VFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLTA
Sbjct: 1021 VFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLTA 1080
Query: 1081 FALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEAREN 1140
FALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEAREN
Sbjct: 1081 FALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEAREN 1140
Query: 1141 SLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDK 1200
SLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDK
Sbjct: 1141 SLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDK 1200
Query: 1201 THPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLN 1260
THPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLN
Sbjct: 1201 THPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLN 1260
Query: 1261 LKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHK 1320
LKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHK
Sbjct: 1261 LKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHK 1320
Query: 1321 GALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLK 1380
GALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLK
Sbjct: 1321 GALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLK 1380
Query: 1381 IDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLK 1440
IDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLK
Sbjct: 1381 IDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLK 1440
Query: 1441 ALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHR 1500
ALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHR
Sbjct: 1441 ALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHR 1500
Query: 1501 PDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYA 1560
PDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYA
Sbjct: 1501 PDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYA 1560
Query: 1561 YKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIM 1620
YKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIM
Sbjct: 1561 YKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIM 1620
Query: 1621 GKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC 1676
GKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC
Sbjct: 1621 GKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC 1676
>gi|115298678 complement component 3 precursor [Homo sapiens]
Length = 1663
Score = 675 bits (1741), Expect = 0.0
Identities = 473/1698 (27%), Positives = 817/1698 (48%), Gaps = 106/1698 (6%)
Query: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
Y I P I R+ + E +V++ + T+++ +P KK SS L+ +
Sbjct: 26 YSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGN 85
Query: 83 AILTIQP-KQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSV 141
TI ++ + +V ++ K + ++ +G+LFI TDK +YTP +V
Sbjct: 86 VTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTV 145
Query: 142 KVRVYSLNDDLKPAKRETVLTFIDPEGSEV--DMVEEIDHIGIISFPDFKIPSNPRYGMW 199
R++++N L P R ++ +PEG V D + + +G++ + IP G W
Sbjct: 146 LYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPL-SWDIPELVNMGQW 204
Query: 200 TIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKV 259
I+A Y+ + FEVKEYVLP F V +EP F N K E+TI AR+ Y K
Sbjct: 205 KIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKK 264
Query: 260 VTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDLN 319
V E ++ FGI++ +Q+ + +++ + +G +V + + + EDL
Sbjct: 265 V-EGTAFVIFGIQDG---EQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLV 320
Query: 320 NKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSL 379
K LY++ TVI +G +AE GI V SPY+++ TP + KPG+P+ + V V +
Sbjct: 321 GKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPD 380
Query: 380 DQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEFNVKTDA 439
VPV + + D +S+T+ DGVA +N L V+T
Sbjct: 381 GSPAYRVPVAVQGE-----------DTVQSLTQ-GDGVAKLSINTHPSQKPLSITVRTKK 428
Query: 440 PDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNI--IVTPKSPYIDKIT 497
+L E QA +A+ YS++ S Y+ + L GE LN+ ++ + KI
Sbjct: 429 QELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIR 488
Query: 498 HYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQ-TAELVS 556
+Y YLI++KG+++ G + + + + +T + +PS RL+ YY + G E+V+
Sbjct: 489 YYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVA 548
Query: 557 DSVWLNIEEKCGNQLQVHLSPDADAYS-PGQTVSLNMATGMDSWVALAAVDSAVYGVQRG 615
DSVW+++++ C L V D PGQ ++L + + V L AVD V+ + +
Sbjct: 549 DSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKK 608
Query: 616 AKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANADDSQENDEPCKE-ILR 674
K +++ +EK+D+GC G G + A VF AGLTF +++ +Q + C + R
Sbjct: 609 NKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAAR 668
Query: 675 PRRTLQ---KKIEEIAAKYKHSVVKKCCYDGACVNNDE-TCEQRAARISLGPRCIKAFTE 730
RR++Q K+++++ K ++KCC DG N +C++R ISLG C K F +
Sbjct: 669 RRRSVQLTEKRMDKVGKYPKE--LRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLD 726
Query: 731 CCVVASQLR---ANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLVPR----- 782
CC ++LR A SH + L + ++ RS FPESWLW V +
Sbjct: 727 CCNYITELRRQHARASHLGLARSNLD-EDIIAEENIVSRSEFPESWLWNVEDLKEPPKNG 785
Query: 783 --RKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDVFLEMNIPYSVVRGEQI 839
K + L DS+TTWEI V +S+ GICVAD + V +D F+++ +PYSVVR EQ+
Sbjct: 786 ISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQV 845
Query: 840 QLKGTVYNYRTSG-MQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTF 898
+++ +YNYR + ++ V++ C+ + HQ T + + SS V +
Sbjct: 846 EIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVT-------IPPKSSLSVPY 898
Query: 899 TVLPLEIGLHNINFSLETW--FGKEILVKTLRVVPEGVKRESYSGV-TLDPRGIYGTISR 955
++PL+ GL + + F + + K+L+VVPEG++ V TLDP + +
Sbjct: 899 VIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQ 958
Query: 956 RKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSV 1015
+++ P D VP TE + + ++G V ++ + E + L P G E ++ +
Sbjct: 959 KEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGM 1018
Query: 1016 VPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSAS 1075
P HYL+ W F L ++Q + +K+G +++R +++ + + S
Sbjct: 1019 TPTVIAVHYLDETEQWEKFG---LEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPS 1075
Query: 1076 TWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPV 1135
TWLTA+ ++V + + +C ++ WL+ Q +G F+E++ ++ G L
Sbjct: 1076 TWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLR- 1134
Query: 1136 EARENSLYLTAFTVIGIRKAFDICP--LVKIDTALIKADNFLLENTLPAQSTFTLAISAY 1193
E + LTAF +I +++A DIC + + ++ KA +FL N + Q ++T+AI+ Y
Sbjct: 1135 NNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGY 1194
Query: 1194 ALS-LGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTA 1252
AL+ +G P ++ K + W+D + + VE T+
Sbjct: 1195 ALAQMGRLKGPLLNKFLTTAKDK----------NRWEDPGKQLYN----------VEATS 1234
Query: 1253 YALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLV---KQLRL 1309
YALL L LKD ++V PV++WL+E++ YGGG+ STQ T + L +Y ++L L
Sbjct: 1235 YALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNL 1294
Query: 1310 SMDIDVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTS 1369
+ + + + H + L R E N+ V T G G T+ V T+ H +
Sbjct: 1295 DVSLQLPSRSSKITHRIHWESASLL-RSEETKENEGFTV-TAEGKGQGTLSVVTMYHAKA 1352
Query: 1370 TSEEVCS-FYLKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISL 1428
+ C+ F LK+ + + R + + C Y+ ++ + S ++DIS+
Sbjct: 1353 KDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMS-----ILDISM 1407
Query: 1429 PTGISANEEDLKALVEGVDQLFTDYQIKDGH-----VILQLNSIPSSDFLCVRFRIFELF 1483
TG + + +DLK L GVD+ + Y++ +I+ L+ + S+ C+ F++ + F
Sbjct: 1408 MTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYF 1467
Query: 1484 EVGFLSPATFTVYEYHRPDKQCTMFY--STSNIKIQKVCEGAACKCVEADCGQMQEELDL 1541
V + P VY Y+ ++ CT FY + K+ K+C C+C E +C ++ D
Sbjct: 1468 NVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENC--FIQKSDD 1525
Query: 1542 TISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFI 1601
++ E R AC+P + Y YK + + + N F +Y + K+G + + TFI
Sbjct: 1526 KVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFI 1585
Query: 1602 KKVTCTNA-ELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTC--SSCQ 1658
+ C A +L + + YL+ G + + YI D TW+E+WP + C Q
Sbjct: 1586 SPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKD--TWVEHWPEEDECQDEENQ 1643
Query: 1659 AFLANLDEFAEDIFLNGC 1676
+L F E + + GC
Sbjct: 1644 KQCQDLGAFTESMVVFGC 1661
>gi|169218213 PREDICTED: similar to complement component C3, partial
[Homo sapiens]
Length = 1295
Score = 546 bits (1406), Expect = e-155
Identities = 377/1308 (28%), Positives = 644/1308 (49%), Gaps = 81/1308 (6%)
Query: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
Y I P I R+ + E +V++ + T+++ +P KK SS L+ +
Sbjct: 26 YSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGN 85
Query: 83 AILTIQP-KQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSV 141
TI ++ + +V ++ K + ++ +G+LFI TDK +YTP +V
Sbjct: 86 VTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTV 145
Query: 142 KVRVYSLNDDLKPAKRETVLTFIDPEGSEV--DMVEEIDHIGIISFPDFKIPSNPRYGMW 199
R++++N L P R ++ +PEG V D + + +G++ + IP G W
Sbjct: 146 LYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPL-SWDIPELVNMGQW 204
Query: 200 TIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKV 259
I+A Y+ + FEVKEYVLP F V +EP F N K E+TI AR+ Y K
Sbjct: 205 KIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKK 264
Query: 260 VTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDLN 319
V E ++ FGI++ +Q+ + +++ + +G +V + + + EDL
Sbjct: 265 V-EGTAFVIFGIQDG---EQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNLRAEDLV 320
Query: 320 NKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSL 379
K LY++ TVI +G +AE GI V SPY+++ TP + KPG+P+ + V V +
Sbjct: 321 GKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPD 380
Query: 380 DQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEFNVKTDA 439
VPV + + D +S+T+ DGVA +N L V+T
Sbjct: 381 GSPAYRVPVAVQGE-----------DTVQSLTQ-GDGVAKLSINTHPSQKPLSITVRTKK 428
Query: 440 PDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNI--IVTPKSPYIDKIT 497
+L E QA +A+ YS++ S Y+ + L GE LN+ ++ + KI
Sbjct: 429 QELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIR 488
Query: 498 HYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQ-TAELVS 556
+Y YLI++KG+++ G + + + + +T + +PS RL+ YY + G E+V+
Sbjct: 489 YYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVA 548
Query: 557 DSVWLNIEEKCGNQLQVHLSPDADAYS-PGQTVSLNMATGMDSWVALAAVDSAVYGVQRG 615
DSVW+++++ C L V D PGQ ++L + + V L AVD V+ + +
Sbjct: 549 DSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKK 608
Query: 616 AKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANADDSQENDEPCKE-ILR 674
K +++ +EK+D+GC G G + A VF AGLTF +++ +Q + C + R
Sbjct: 609 NKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAAR 668
Query: 675 PRRTLQ---KKIEEIAAKYKHSVVKKCCYDGACVNNDE-TCEQRAARISLGPRCIKAFTE 730
RR++Q K+++++ K ++KCC DG N +C++R ISLG C K F +
Sbjct: 669 RRRSVQLTEKRMDKVGKYPKE--LRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLD 726
Query: 731 CCVVASQLR---ANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLVPR----- 782
CC ++LR A SH + L + ++ RS FPESWLW V +
Sbjct: 727 CCNYITELRRQHARASHLGLARSNLD-EDIIAEENIVSRSEFPESWLWNVEDLKEPPKNG 785
Query: 783 --RKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDVFLEMNIPYSVVRGEQI 839
K + L DS+TTWEI V +S+ GICVAD + V +D F+++ +PYSVVR EQ+
Sbjct: 786 ISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQV 845
Query: 840 QLKGTVYNYRTSG-MQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTF 898
+++ +YNYR + ++ V++ C+ + HQ T + + SS V +
Sbjct: 846 EIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVT-------IPPKSSLSVPY 898
Query: 899 TVLPLEIGLHNINFSLETW--FGKEILVKTLRVVPEGVKRESYSGV-TLDPRGIYGTISR 955
++PL+ GL + + F + + K+L+VVPEG++ V TLDP + +
Sbjct: 899 VIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQ 958
Query: 956 RKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSV 1015
+++ P D VP TE + + ++G V ++ + E + L P G E ++ +
Sbjct: 959 KEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGM 1018
Query: 1016 VPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSAS 1075
P HYL+ W F L ++Q + +K+G +++R +++ + + S
Sbjct: 1019 TPTVIAVHYLDETEQWEKFG---LEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPS 1075
Query: 1076 TWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPV 1135
TWLTA+ ++V + + +C ++ WL+ Q +G F+E++ ++ G L
Sbjct: 1076 TWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLR- 1134
Query: 1136 EARENSLYLTAFTVIGIRKAFDICP--LVKIDTALIKADNFLLENTLPAQSTFTLAISAY 1193
E + LTAF +I +++A DIC + + ++ KA +FL N + Q ++T+AI+ Y
Sbjct: 1135 NNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGY 1194
Query: 1194 ALS-LGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTA 1252
AL+ +G P ++ K + W+D + + VE T+
Sbjct: 1195 ALAQMGRLKGPLLNKFLTTAKDK----------NRWEDPGKQLYN----------VEATS 1234
Query: 1253 YALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEY 1300
YALL L LKD ++V PV++WL+E++ YGGG+ STQ T + L +Y
Sbjct: 1235 YALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQY 1282
>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
Length = 1744
Score = 517 bits (1331), Expect = e-146
Identities = 447/1660 (26%), Positives = 750/1660 (45%), Gaps = 163/1660 (9%)
Query: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGII 183
G LF+ TD+P+Y P Q V+ RV++L+ ++P+ +T+ ++ +E+ I
Sbjct: 139 GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPST-DTITVMVENSHGLRVRKKEVYMPSSI 197
Query: 184 SFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEP--EYNFIGYK 241
DF IP G W I A++ + + + FEVK+YVLP+F V I P Y
Sbjct: 198 FQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 242 NFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
+ ++ I+ARY Y K V + Y+ FG+ ++ D +K + T L+NG + ++
Sbjct: 258 HLDEMQLDIQARYIYGKPV-QGVAYVRFGLLDE--DGKKTFFRGLESQTKLVNGQSHISL 314
Query: 302 DS---ETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVA 358
+ A+++L+ + DL LY+A +IE GG EEAE+ +V SP+ L+L
Sbjct: 315 SKAEFQDALEKLNM-GITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 359 TPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQ--ETSDLDPSKSVTRVDDG 416
T L PG P+ ++ V++ G+PV ++A E D+ + G
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTD----GSG 429
Query: 417 VASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKAL 476
S + +P ++ L+ +V +P + A A S +L I+W D+
Sbjct: 430 QVSIPIIIPQTISELQLSVSAGSP-----HPAIARLTVAAPPSGGPGFLSIEWPDSRPPR 484
Query: 477 LVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVP 536
VG+ LN+ + +HY Y+ILS+G+I+ K + S+++ V ++ P
Sbjct: 485 -VGDTLNLNLRAVGSGAT-FSHYYYMILSRGQIVFMNREPK---RTLTSVSVFVDHHLAP 539
Query: 537 SSRLLVYYIVTGEQTAELVSDSVWLNIEE-KCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
S + +Y G+ V++S+ ++++ C +L++ + A Y G++V L++ T
Sbjct: 540 SFYFVAFYY-HGDHP---VANSLRVDVQAGACEGKLELSVD-GAKQYRNGESVKLHLETD 594
Query: 596 MDSWVALAAVDSAVYGVQRGAKKPLE--RVFQFLEKSDLGCGAGGGLNNANVFHLAGLTF 653
+ VAL A+D+A+Y + KPL +VF+ + DLGCG GGG + VF AGL F
Sbjct: 595 SLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAF 654
Query: 654 LTNANADDSQENDE-PCKEILRPRRTL--QKKIEEIAAKYKHSVVKKCCYDGAC-VNNDE 709
S++ P ++ R +R + QK I E +Y K+CC DG +
Sbjct: 655 SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMR 714
Query: 710 TCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQ-----LGRLHMKTLLPVSKPE 764
+CEQRAAR+ P C + F CC A LR K L L + L+
Sbjct: 715 SCEQRAARVQQ-PDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIP 773
Query: 765 IRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDV 823
+RS+FPE+WLW V V R + L LPDSLTTWEI G+ +S T G+CVA V+ +VF++
Sbjct: 774 VRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREF 833
Query: 824 FLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKC 883
L + +P SV R EQ++L+ +YNY + V +S VEG+C + + Q
Sbjct: 834 HLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQ------- 886
Query: 884 VRQKVEGSSSHLVTFTVLPLEIGLHNINF----SLETWFGKEILVKTLRVVPEG-VKRES 938
V S+ V F+V+P ++ S E G + + K L++ EG + RE
Sbjct: 887 --VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVG-DAVSKVLQIEKEGAIHREE 943
Query: 939 --YSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA--VLSQ 994
Y LD RG R E P +++P + + V + L + LS
Sbjct: 944 LVYELNPLDHRG------RTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 995 EGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGML 1054
G+ L LP+G E ++ + P YL+ W+ P K +++G +
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTL---PPETKDHAVDLIQKGYM 1054
Query: 1055 SIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLD 1114
I +R AD SY+ W +STWLTAF L+VL + V + + + WL+ Q D
Sbjct: 1055 RIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQAD 1114
Query: 1115 NGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC------PL-VKIDTA 1167
GSF++ +QG L + ++ LTAF I + + PL +++ +
Sbjct: 1115 -GSFQDPCPVLDRSMQGGL--VGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEAS 1171
Query: 1168 LIKADNFLLEN-TLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYR 1226
+ KA++FL E + AI+AYAL+L + L A G+
Sbjct: 1172 ISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGD---NL 1228
Query: 1227 FWKDNLQHKDSSVPNTGTAR------------MVETTAYALL-TSLNLKDINYVNPVIKW 1273
+W + ++V T R +ETTAYALL L+ + W
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAW 1288
Query: 1274 LSEEQRYGGGFYSTQDTINAIEGLTEY---SLLVKQLRLSMDIDVSYKHKGALHNYKMTD 1330
L+ + + GGF STQDT+ A++ L+ Y S ++ L++ + + ++ H ++ +
Sbjct: 1289 LTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNN 1348
Query: 1331 KNFLG--RPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEA 1388
+ G ++ L + V G G+ T+ V + C L+I+
Sbjct: 1349 RQIRGLEEELQFSLGSKINVKVG-GNSKGTLKVLRTYNVLDMKNTTCQ-DLQIEVTVKGH 1406
Query: 1389 SHYRGYGNSDY------------------KRIVACASYKPSR-----------EESSSG- 1418
Y N DY + + ++ R EE S
Sbjct: 1407 VEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRV 1466
Query: 1419 --------------SSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQL 1464
S A+ D++L +G A DL+ L D+ + ++ + HV+L
Sbjct: 1467 HYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYF 1526
Query: 1465 NSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYS--TSNIKIQKVCEG 1522
+S+P+S CV F + VG + PA+ T+Y+Y+ P+++C++FY + + + +C
Sbjct: 1527 DSVPTSR-ECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSA 1585
Query: 1523 AACKCVEADCGQMQEELDLTISAET--RKQTAC-KPEIAYAYKVSITSITVENVFVKYKA 1579
C+C E C + + L+ + E R + AC P + Y ++V + F ++
Sbjct: 1586 EVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFET 1645
Query: 1580 TLLDI-YKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYP 1638
+ + + T + A + F+ + +C L G++YLIMG + Y+ Y
Sbjct: 1646 KITQVLHFTKDVKAAANQMRNFLVRASC-RLRLEPGKEYLIMGLDG--ATYDLEGHPQYL 1702
Query: 1639 LDSLTWIEYWPRDTTCSSC--QAFLANLDEFAEDIFLNGC 1676
LDS +WIE P + C S +A A L++F ++ GC
Sbjct: 1703 LDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742
>gi|178557739 complement component 4B preproprotein [Homo sapiens]
Length = 1744
Score = 515 bits (1326), Expect = e-145
Identities = 450/1661 (27%), Positives = 753/1661 (45%), Gaps = 165/1661 (9%)
Query: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGII 183
G LF+ TD+P+Y P Q V+ RV++L+ ++P+ +T+ ++ +E+ I
Sbjct: 139 GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPST-DTITVMVENSHGLRVRKKEVYMPSSI 197
Query: 184 SFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEP--EYNFIGYK 241
DF IP G W I A++ + + + FEVK+YVLP+F V I P Y
Sbjct: 198 FQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 242 NFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
+ ++ I+ARY Y K V + Y+ FG+ ++ D +K + T L+NG + ++
Sbjct: 258 HLDEMQLDIQARYIYGKPV-QGVAYVRFGLLDE--DGKKTFFRGLESQTKLVNGQSHISL 314
Query: 302 DS---ETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVA 358
+ A+++L+ + DL LY+A +IES GG EEAE+ +V SP+ L+L
Sbjct: 315 SKAEFQDALEKLNM-GITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 359 TPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQ--ETSDLDPSKSVTRVDDG 416
T L PG P+ ++ V++ G+PV ++A E D+ + G
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTD----GSG 429
Query: 417 VASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKAL 476
S + +P ++ L+ +V +P + A A S +L I+ D+
Sbjct: 430 QVSIPIIIPQTISELQLSVSAGSP-----HPAIARLTVAAPPSGGPGFLSIERPDSRPPR 484
Query: 477 LVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVP 536
VG+ LN+ + +HY Y+ILS+G+I+ K + S+++ V ++ P
Sbjct: 485 -VGDTLNLNLRAVGSGAT-FSHYYYMILSRGQIVFMNREPK---RTLTSVSVFVDHHLAP 539
Query: 537 SSRLLVYYIVTGEQTAELVSDSVWLNIEE-KCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
S + +Y G+ V++S+ ++++ C +L++ + A Y G++V L++ T
Sbjct: 540 SFYFVAFYY-HGDHP---VANSLRVDVQAGACEGKLELSVD-GAKQYRNGESVKLHLETD 594
Query: 596 MDSWVALAAVDSAVYGVQRGAKKPLE--RVFQFLEKSDLGCGAGGGLNNANVFHLAGLTF 653
+ VAL A+D+A+Y + KPL +VF+ + DLGCG GGG + VF AGL F
Sbjct: 595 SLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAF 654
Query: 654 LTNANADDSQENDE-PCKEILRPRRTL--QKKIEEIAAKYKHSVVKKCCYDGAC-VNNDE 709
S++ P ++ R +R + QK I E +Y K+CC DG +
Sbjct: 655 SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMR 714
Query: 710 TCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQ-----LGRLHMKTLLPVSKPE 764
+CEQRAAR+ P C + F CC A LR K L L + L+
Sbjct: 715 SCEQRAARVQQ-PDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIP 773
Query: 765 IRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDV 823
+RS+FPE+WLW V V R + L LPDSLTTWEI G+ +S T G+CVA V+ +VF++
Sbjct: 774 VRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREF 833
Query: 824 FLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKC 883
L + +P SV R EQ++L+ +YNY + V +S VEG+C + + Q
Sbjct: 834 HLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQ------- 886
Query: 884 VRQKVEGSSSHLVTFTVLPLEIGLHNINF----SLETWFGKEILVKTLRVVPEG-VKRES 938
V S+ V F+V+P ++ S E G + + K L++ EG + RE
Sbjct: 887 --VLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPVG-DAVSKVLQIEKEGAIHREE 943
Query: 939 --YSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA--VLSQ 994
Y LD RG R E P +++P + + V + L + LS
Sbjct: 944 LVYELNPLDHRG------RTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 995 EGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGML 1054
G+ L LP+G E ++ + P YL+ W+ P K +++G +
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTL---PPETKDHAVDLIQKGYM 1054
Query: 1055 SIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLD 1114
I +R AD SY+ W +STWLTAF L+VL + V + + + WL+ Q D
Sbjct: 1055 RIQQFRKADGSYAAWLSRGSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQAD 1114
Query: 1115 NGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC------PL-VKIDTA 1167
GSF++ S +QG L + ++ LTAF I + + PL +++ +
Sbjct: 1115 -GSFQDLSPVIHRSMQGGL--VGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEAS 1171
Query: 1168 LIKADNFLLEN-TLPAQSTFTLAISAYALSLGDKTHPQFRSIV-SALKREALVKGNPPIY 1225
+ KA +FL E + AI+AYAL+L K R + + L A G+
Sbjct: 1172 ISKASSFLGEKASAGLLGAHAAAITAYALTL-TKAPADLRGVAHNNLMAMAQETGD---N 1227
Query: 1226 RFWKDNLQHKDSSVPNTGTAR------------MVETTAYALL-TSLNLKDINYVNPVIK 1272
+W + ++V T R +ETTAYALL L+ +
Sbjct: 1228 LYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAA 1287
Query: 1273 WLSEEQRYGGGFYSTQDTINAIEGLTEY---SLLVKQLRLSMDIDVSYKHKGALHNYKMT 1329
WL+ + + GGF STQDT+ A++ L+ Y S ++ L++ + + ++ H ++
Sbjct: 1288 WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLN 1347
Query: 1330 DKNFLG--RPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIE 1387
++ G ++ L + V G G+ T+ V + C L+I+
Sbjct: 1348 NRQIRGLEEELQFSLGSKINVKVG-GNSKGTLKVLRTYNVLDMKNTTCQ-DLQIEVTVKG 1405
Query: 1388 ASHYRGYGNSDY------------------KRIVACASYKPSR-----------EESSSG 1418
Y N DY + + ++ R EE S
Sbjct: 1406 HVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESR 1465
Query: 1419 ---------------SSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQ 1463
S A+ D++L +G A DL+ L D+ + ++ + HV+L
Sbjct: 1466 VHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLY 1525
Query: 1464 LNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYS--TSNIKIQKVCE 1521
+S+P+S CV F + VG + PA+ T+Y+Y+ P+++C++FY + + + +C
Sbjct: 1526 FDSVPTSR-ECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCS 1584
Query: 1522 GAACKCVEADCGQMQEELDLTISAET--RKQTAC-KPEIAYAYKVSITSITVENVFVKYK 1578
C+C E C + + L+ + E R + AC P + Y ++V + F ++
Sbjct: 1585 AEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFE 1644
Query: 1579 ATLLDI-YKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIY 1637
+ + + T + A + F+ + +C L G++YLIMG + Y+ Y
Sbjct: 1645 TKITQVLHFTKDVKAAANQMRNFLVRASC-RLRLEPGKEYLIMGLDG--ATYDLEGHPQY 1701
Query: 1638 PLDSLTWIEYWPRDTTCSSC--QAFLANLDEFAEDIFLNGC 1676
LDS +WIE P + C S +A A L++F ++ GC
Sbjct: 1702 LLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742
>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
sapiens]
Length = 1698
Score = 515 bits (1326), Expect = e-145
Identities = 439/1617 (27%), Positives = 742/1617 (45%), Gaps = 123/1617 (7%)
Query: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGII 183
G LF+ TD+P+Y P Q V+ RV++L+ ++P+ +T+ ++ +E+ I
Sbjct: 139 GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPST-DTITVMVENSHGLRVRKKEVYMPSSI 197
Query: 184 SFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEP--EYNFIGYK 241
DF IP G W I A++ + + + FEVK+YVLP+F V I P Y
Sbjct: 198 FQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 242 NFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
+ ++ I+ARY Y K V + Y+ FG+ ++ D +K + T L+NG + ++
Sbjct: 258 HLDEMQLDIQARYIYGKPV-QGVAYVRFGLLDE--DGKKTFFRGLESQTKLVNGQSHISL 314
Query: 302 DS---ETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVA 358
+ A+++L+ + DL LY+A +IE GG EEAE+ +V SP+ L+L
Sbjct: 315 SKAEFQDALEKLNM-GITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 359 TPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQ--ETSDLDPSKSVTRVDDG 416
T L PG P+ ++ V++ G+PV ++A E D+ + G
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTD----GSG 429
Query: 417 VASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKAL 476
S + +P ++ L+ +V +P + A A S +L I+W D+
Sbjct: 430 QVSIPIIIPQTISELQLSVSAGSP-----HPAIARLTVAAPPSGGPGFLSIEWPDSRPPR 484
Query: 477 LVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVP 536
VG+ LN+ + +HY Y+ILS+G+I+ K + S+++ V ++ P
Sbjct: 485 -VGDTLNLNLRAVGSGAT-FSHYYYMILSRGQIVFMNREPK---RTLTSVSVFVDHHLAP 539
Query: 537 SSRLLVYYIVTGEQTAELVSDSVWLNIEE-KCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
S + +Y G+ V++S+ ++++ C +L++ + A Y G++V L++ T
Sbjct: 540 SFYFVAFYY-HGDHP---VANSLRVDVQAGACEGKLELSVD-GAKQYRNGESVKLHLETD 594
Query: 596 MDSWVALAAVDSAVYGVQRGAKKPLE--RVFQFLEKSDLGCGAGGGLNNANVFHLAGLTF 653
+ VAL A+D+A+Y + KPL +VF+ + DLGCG GGG + VF AGL F
Sbjct: 595 SLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAF 654
Query: 654 LTNANADDSQENDE-PCKEILRPRRTL--QKKIEEIAAKYKHSVVKKCCYDGAC-VNNDE 709
S++ P ++ R +R + QK I E +Y K+CC DG +
Sbjct: 655 SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMR 714
Query: 710 TCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQ-----LGRLHMKTLLPVSKPE 764
+CEQRAAR+ P C + F CC A LR K L L + L+
Sbjct: 715 SCEQRAARVQQ-PDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIP 773
Query: 765 IRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDV 823
+RS+FPE+WLW V V R + L LPDSLTTWEI G+ +S T G+CVA V+ +VF++
Sbjct: 774 VRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREF 833
Query: 824 FLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKC 883
L + +P SV R EQ++L+ +YNY + V +S VEG+C + + Q
Sbjct: 834 HLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQ------- 886
Query: 884 VRQKVEGSSSHLVTFTVLPLEIGLHNINF----SLETWFGKEILVKTLRVVPEG-VKRES 938
V S+ V F+V+P ++ S E G + + K L++ EG + RE
Sbjct: 887 --VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVG-DAVSKVLQIEKEGAIHREE 943
Query: 939 --YSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA--VLSQ 994
Y LD RG R E P +++P + + V + L + LS
Sbjct: 944 LVYELNPLDHRG------RTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 995 EGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGML 1054
G+ L LP+G E ++ + P YL+ W+ P K +++G +
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTL---PPETKDHAVDLIQKGYM 1054
Query: 1055 SIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLD 1114
I +R AD SY+ W +STWLTAF L+VL + V + + + WL+ Q D
Sbjct: 1055 RIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQAD 1114
Query: 1115 NGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC------PL-VKIDTA 1167
GSF++ +QG L + ++ LTAF I + + PL +++ +
Sbjct: 1115 -GSFQDPCPVLDRSMQGGL--VGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEAS 1171
Query: 1168 LIKADNFLLEN-TLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYR 1226
+ KA++FL E + AI+AYAL+L + L A G+
Sbjct: 1172 ISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGD---NL 1228
Query: 1227 FWKDNLQHKDSSVPNTGTAR------------MVETTAYALL-TSLNLKDINYVNPVIKW 1273
+W + ++V T R +ETTAYALL L+ + W
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAW 1288
Query: 1274 LSEEQRYGGGFYSTQDTINAIEGLTEY---SLLVKQLRLSMDIDVSYKHKGALHNYKMTD 1330
L+ + + GGF STQDT+ A++ L+ Y S ++ L++ + + ++ H ++ +
Sbjct: 1289 LTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNN 1348
Query: 1331 KNFLG--RPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEA 1388
+ G ++ L + V G G+ T+ V + C L+I+
Sbjct: 1349 RQIRGLEEELQFSLGSKINVKVG-GNSKGTLKVLRTYNVLDMKNTTCQ-DLQIEVTVKGH 1406
Query: 1389 SHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTG-ISANEEDLKALVEGVD 1447
Y N DY+ P++++ + V + L G + + L D
Sbjct: 1407 VEYTMEANEDYEDYE--YDELPAKDDPDA-PLQPVTPLQLFEGRRNRRRREAPKLTSLSD 1463
Query: 1448 QLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTM 1507
+ + ++ + HV+L +S+P+S CV F + VG + PA+ T+Y+Y+ P+++C++
Sbjct: 1464 RYVSHFETEGPHVLLYFDSVPTSR-ECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSV 1522
Query: 1508 FYS--TSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAET--RKQTAC-KPEIAYAYK 1562
FY + + + +C C+C E C + + L+ + E R + AC P + Y ++
Sbjct: 1523 FYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQ 1582
Query: 1563 VSITSITVENVFVKYKATLLDI-YKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMG 1621
V + F ++ + + + T + A + F+ + +C L G++YLIMG
Sbjct: 1583 VKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASC-RLRLEPGKEYLIMG 1641
Query: 1622 KEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSC--QAFLANLDEFAEDIFLNGC 1676
+ Y+ Y LDS +WIE P + C S +A A L++F ++ GC
Sbjct: 1642 LDG--ATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1696
>gi|67190748 complement component 4A preproprotein [Homo sapiens]
Length = 1744
Score = 513 bits (1322), Expect = e-145
Identities = 447/1660 (26%), Positives = 750/1660 (45%), Gaps = 163/1660 (9%)
Query: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGII 183
G LF+ TD+P+Y P Q V+ RV++L+ ++P+ +T+ ++ +E+ I
Sbjct: 139 GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPST-DTITVMVENSHGLRVRKKEVYMPSSI 197
Query: 184 SFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEP--EYNFIGYK 241
DF IP G W I A++ + + + FEVK+YVLP+F V I P Y
Sbjct: 198 FQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 242 NFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
+ ++ I+ARY Y K V + Y+ FG+ ++ D +K + T L+NG + ++
Sbjct: 258 HLDEMQLDIQARYIYGKPV-QGVAYVRFGLLDE--DGKKTFFRGLESQTKLVNGQSHISL 314
Query: 302 DS---ETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVA 358
+ A+++L+ + DL LY+A +IES GG EEAE+ +V SP+ L+L
Sbjct: 315 SKAEFQDALEKLNM-GITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 359 TPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQ--ETSDLDPSKSVTRVDDG 416
T L PG P+ ++ V++ G+PV ++A E D+ + G
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTD----GSG 429
Query: 417 VASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKAL 476
S + +P ++ L+ +V +P + A A S +L I+ D+
Sbjct: 430 QVSIPIIIPQTISELQLSVSAGSP-----HPAIARLTVAAPPSGGPGFLSIERPDSRPPR 484
Query: 477 LVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVP 536
VG+ LN+ + +HY Y+ILS+G+I+ K + S+++ V ++ P
Sbjct: 485 -VGDTLNLNLRAVGSGAT-FSHYYYMILSRGQIVFMNREPK---RTLTSVSVFVDHHLAP 539
Query: 537 SSRLLVYYIVTGEQTAELVSDSVWLNIEE-KCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
S + +Y G+ V++S+ ++++ C +L++ + A Y G++V L++ T
Sbjct: 540 SFYFVAFYY-HGDHP---VANSLRVDVQAGACEGKLELSVD-GAKQYRNGESVKLHLETD 594
Query: 596 MDSWVALAAVDSAVYGVQRGAKKPLE--RVFQFLEKSDLGCGAGGGLNNANVFHLAGLTF 653
+ VAL A+D+A+Y + KPL +VF+ + DLGCG GGG + VF AGL F
Sbjct: 595 SLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAF 654
Query: 654 LTNANADDSQENDE-PCKEILRPRRTL--QKKIEEIAAKYKHSVVKKCCYDGAC-VNNDE 709
S++ P ++ R +R + QK I E +Y K+CC DG +
Sbjct: 655 SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMR 714
Query: 710 TCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQ-----LGRLHMKTLLPVSKPE 764
+CEQRAAR+ P C + F CC A LR K L L + L+
Sbjct: 715 SCEQRAARVQQ-PDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIP 773
Query: 765 IRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDV 823
+RS+FPE+WLW V V R + L LPDSLTTWEI G+ +S T G+CVA V+ +VF++
Sbjct: 774 VRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREF 833
Query: 824 FLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKC 883
L + +P SV R EQ++L+ +YNY + V +S VEG+C + + Q
Sbjct: 834 HLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQ------- 886
Query: 884 VRQKVEGSSSHLVTFTVLPLEIGLHNINF----SLETWFGKEILVKTLRVVPEG-VKRES 938
V S+ V F+V+P ++ S E G + + K L++ EG + RE
Sbjct: 887 --VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVG-DAVSKVLQIEKEGAIHREE 943
Query: 939 --YSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA--VLSQ 994
Y LD RG R E P +++P + + V + L + LS
Sbjct: 944 LVYELNPLDHRG------RTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 995 EGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGML 1054
G+ L LP+G E ++ + P YL+ W+ P K +++G +
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTL---PPETKDHAVDLIQKGYM 1054
Query: 1055 SIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLD 1114
I +R AD SY+ W +STWLTAF L+VL + V + + + WL+ Q D
Sbjct: 1055 RIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQAD 1114
Query: 1115 NGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC------PL-VKIDTA 1167
GSF++ +QG L + ++ LTAF I + + PL +++ +
Sbjct: 1115 -GSFQDPCPVLDRSMQGGL--VGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEAS 1171
Query: 1168 LIKADNFLLEN-TLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYR 1226
+ KA++FL E + AI+AYAL+L + L A G+
Sbjct: 1172 ISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGD---NL 1228
Query: 1227 FWKDNLQHKDSSVPNTGTAR------------MVETTAYALL-TSLNLKDINYVNPVIKW 1273
+W + ++V T R +ETTAYALL L+ + W
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAW 1288
Query: 1274 LSEEQRYGGGFYSTQDTINAIEGLTEY---SLLVKQLRLSMDIDVSYKHKGALHNYKMTD 1330
L+ + + GGF STQDT+ A++ L+ Y S ++ L++ + + ++ H ++ +
Sbjct: 1289 LTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNN 1348
Query: 1331 KNFLG--RPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEA 1388
+ G ++ L + V G G+ T+ V + C L+I+
Sbjct: 1349 RQIRGLEEELQFSLGSKINVKVG-GNSKGTLKVLRTYNVLDMKNTTCQ-DLQIEVTVKGH 1406
Query: 1389 SHYRGYGNSDY------------------KRIVACASYKPSR-----------EESSSG- 1418
Y N DY + + ++ R EE S
Sbjct: 1407 VEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRV 1466
Query: 1419 --------------SSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQL 1464
S A+ D++L +G A DL+ L D+ + ++ + HV+L
Sbjct: 1467 HYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYF 1526
Query: 1465 NSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYS--TSNIKIQKVCEG 1522
+S+P+S CV F + VG + PA+ T+Y+Y+ P+++C++FY + + + +C
Sbjct: 1527 DSVPTSR-ECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSA 1585
Query: 1523 AACKCVEADCGQMQEELDLTISAET--RKQTAC-KPEIAYAYKVSITSITVENVFVKYKA 1579
C+C E C + + L+ + E R + AC P + Y ++V + F ++
Sbjct: 1586 EVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFET 1645
Query: 1580 TLLDI-YKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYP 1638
+ + + T + A + F+ + +C L G++YLIMG + Y+ Y
Sbjct: 1646 KITQVLHFTKDVKAAANQMRNFLVRASC-RLRLEPGKEYLIMGLDG--ATYDLEGHPQYL 1702
Query: 1639 LDSLTWIEYWPRDTTCSSC--QAFLANLDEFAEDIFLNGC 1676
LDS +WIE P + C S +A A L++F ++ GC
Sbjct: 1703 LDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742
>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
Length = 1474
Score = 268 bits (686), Expect = 3e-71
Identities = 346/1556 (22%), Positives = 636/1556 (40%), Gaps = 204/1556 (13%)
Query: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
Y++ P + +E + + E + S++S + ++ L +EN +
Sbjct: 31 YMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTD----LEAENDVLHC 86
Query: 83 AILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSVK 142
+ PK + V ++ ++ F K + + ++ +F+ TDK +Y P Q+VK
Sbjct: 87 VAFAV-PKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVK 145
Query: 143 VRVYSLNDDLKPAKRETVLTFI-DPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWTI 201
RV S++++ P L +I DP+G+ + + G + F + S P G + +
Sbjct: 146 FRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKV 205
Query: 202 KAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKVV- 260
+ K T F V+E+VLP F V + + N +++ Y Y K V
Sbjct: 206 VVQKKSGGRTEHP--FTVEEFVLPKFEVQVTVPKIITILEEEMN--VSVCGLYTYGKPVP 261
Query: 261 --TEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDL 318
+ + D + + + +G ++ + Y ++
Sbjct: 262 GHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLH 321
Query: 319 NNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDS 378
+ TV+E TG S E + KL+ V + GIP+ +V++ D
Sbjct: 322 TEAQIQEEGTVVELTGRQSSEI-------TRTITKLSFVKVDSHFRQGIPFFGQVRLVDG 374
Query: 379 LDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLN----LPSGVTVLEFN 434
GVP+ I N+ + T + G+ F +N + + +TV N
Sbjct: 375 K-----GVPIPNKVIFIRGNEANY----YSNATTDEHGLVQFSINTTNVMGTSLTV-RVN 424
Query: 435 VKTDAPDLPEE--NQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNIIVTPKSPY 492
K +P + ++ E AY S S ++ L G T ++ Y
Sbjct: 425 YKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGH----TQTVQAHY 480
Query: 493 I---------DKITHYNYLILSKGKIIHFGTR----EKFSDASYQSINIPVTQNMVPSSR 539
I K++ Y YLI++KG I+ GT ++ + SI+IPV ++ P +R
Sbjct: 481 ILNGGTLLGLKKLSFY-YLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVAR 539
Query: 540 LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSW 599
LL+Y ++ T +++ DS ++E N++ + SP P L + S
Sbjct: 540 LLIYAVLP---TGDVIGDSAKYDVENCLANKVDLSFSPSQSL--PASHAHLRVTAAPQSV 594
Query: 600 VALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLN--------NANVFHLAGL 651
AL AVD +V ++ A+ V+ L + DL G G LN N + ++ G+
Sbjct: 595 CALRAVDQSVLLMKPDAELSASSVYNLLPEKDL-TGFPGPLNDQDDEDCINRHNVYINGI 653
Query: 652 TFLTNANADDSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETC 711
T+ ++ ++ + + +E++ K + + + + C
Sbjct: 654 TYTPVSSTNE---------------KDMYSFLEDMGLK---------AFTNSKIRKPKMC 689
Query: 712 EQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPE---IRSY 768
Q GP LR D+ +GR H + L+ V +P +R Y
Sbjct: 690 PQLQQYEMHGPE-------------GLRVGFYESDV-MGRGHAR-LVHVEEPHTETVRKY 734
Query: 769 FPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFKDVFL 825
FPE+W+W++ +V ++ +PD++T W+ +S + G+ ++ T + F+ F+
Sbjct: 735 FPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFV 794
Query: 826 EMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVR 885
E+ +PYSV+RGE LK TV NY ++ V++ A + + ++ C+
Sbjct: 795 ELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFL-----AVPVEKEQAPHCIC 849
Query: 886 QKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEI----------------LVKTLRV 929
+ V++ V P +G N S E +E+ ++K L V
Sbjct: 850 ----ANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLV 905
Query: 930 VPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILS 989
PEG+++E+ L P G G +S +E ++P ++V ++ + +SV G ++G
Sbjct: 906 EPEGLEKETTFNSLLCPSG--GEVS--EELSLKLPPNVVEES-ARASVSVLGDILGS--- 957
Query: 990 AVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKL 1049
+ + L +P G E ++ P YV YL P I K K L
Sbjct: 958 ---AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLT-----PEI-KSKAIGYL 1008
Query: 1050 KEGMLSIMSYRNADYSYSV----WKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLL 1105
G ++Y++ D SYS + +TWLTAF L+ Q Y+ ++ I +L+
Sbjct: 1009 NTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALI 1068
Query: 1106 WLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKID 1165
WL + Q DNG F+ + ++G + E+ + L+A+ I + + PL +
Sbjct: 1069 WLSQR-QKDNGCFRSSGSLLNNAIKGGV-----EDEVTLSAYITIALLE----IPLT-VT 1117
Query: 1166 TALIKADNFLLENTLP-------AQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALV 1218
+++ F LE+ +T A+ AYA +L + + ++ +L EA+
Sbjct: 1118 HPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKR-KEVLKSLNEEAVK 1176
Query: 1219 KGNPPIY-RFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNL------KDINYVNPVI 1271
K N + R K P +A VE T+Y LL L +D+ ++
Sbjct: 1177 KDNSVHWERPQKPKAPVGHFYEPQAPSAE-VEMTSYVLLAYLTAQPAPTSEDLTSATNIV 1235
Query: 1272 KWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDK 1331
KW++++Q GGF STQDT+ A+ L++Y R V+ + G + D
Sbjct: 1236 KWITKQQNAQGGFSSTQDTVVALHALSKYG-AATFTRTGKAAQVTIQSSGTFSSKFQVDN 1294
Query: 1332 N--FLGRPVEV--LLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIE 1387
N L + V + L + + TG G T++ + +E F L + T
Sbjct: 1295 NNRLLLQQVSLPELPGEYSMKVTGEG---CVYLQTSLKYNILPEKEEFPFALGVQTLPQT 1351
Query: 1388 ASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVD 1447
+ + + +I SY SR S S+ A++D+ + +G + +K L
Sbjct: 1352 CDEPKAHTSF---QISLSVSYTGSR----SASNMAIVDVKMVSGFIPLKPTVKMLERSNH 1404
Query: 1448 QLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDK 1503
T ++ HV++ L+ + S+ L + F + + V L PA VY+Y+ D+
Sbjct: 1405 VSRT--EVSSNHVLIYLDKV-SNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDE 1457
>gi|162809334 pregnancy-zone protein [Homo sapiens]
Length = 1482
Score = 186 bits (473), Expect = 1e-46
Identities = 188/791 (23%), Positives = 340/791 (42%), Gaps = 104/791 (13%)
Query: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
+RSYFPE+W+WE+ V ++ +PD++T W+ +S + G+ ++ T + F+
Sbjct: 737 VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796
Query: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTK-- 879
F+E+ +PYSV+RGE LK TV NY ++ V++ A S Q TK
Sbjct: 797 PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLAS-------QNTKGE 849
Query: 880 SSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWF------------------GKE 921
S C+ G+ +++TV P +G N+NFS+ K+
Sbjct: 850 ESYCIC----GNERQTLSWTVTPKTLG--NVNFSVSAEAMQSLELCGNEVVEVPEIKRKD 903
Query: 922 ILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKG 981
++KTL V EG+++E T + ++ ++P ++V K + SV G
Sbjct: 904 TVIKTLLVEAEGIEQEK----TFSSMTCASGANVSEQLSLKLPSNVV-KESARASFSVLG 958
Query: 982 LLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIE 1041
++G + + I L +P G E ++ P YV +YL + L +
Sbjct: 959 DILGS------AMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLN--------ETQQLTQ 1004
Query: 1042 KQKLKK--KLKEGMLSIMSYRNADYSYSV----WKGGSASTWLTAFALRVLGQVNKYVEQ 1095
+ K K L G ++Y++ D SYS + +TWLTAF L+ Q Y+
Sbjct: 1005 EIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFI 1064
Query: 1096 NQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKA 1155
++ I SL WL Q DNG F+ + ++G + EA L+A+ I + +
Sbjct: 1065 DEAHITQSLTWL-SQMQKDNGCFRSSGSLLNNAIKGGVEDEAT-----LSAYVTIALLE- 1117
Query: 1156 FDICPLVKIDTALIKADNFLLENT-------LPAQSTFTLAISAYALSLGDKTHPQFRSI 1208
PL + +++ F LE+ +T A+ AYA SL K + Q R I
Sbjct: 1118 ---IPL-PVTNPIVRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQN-QNREI 1172
Query: 1209 VSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNLK------ 1262
+++L +EA+ + N + + + VE T+Y LL L +
Sbjct: 1173 LNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSG 1232
Query: 1263 DINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGA 1322
D+ ++KW+ ++Q GGF STQDT+ A+ L+ Y R V+ +
Sbjct: 1233 DLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYG-AATFTRTEKTAQVTVQDSQT 1291
Query: 1323 LHNYKMTDKNFLGRPVEVLLND---DLIVSTGFGSGLATVHV-TTVVHKTSTSEEVCSFY 1378
D N L ++ L + + +++ +G V++ T++ + +E F
Sbjct: 1292 FSTNFQVDNNNLLLLQQISLPELPGEYVITV---TGERCVYLQTSMKYNILPEKEDSPFA 1348
Query: 1379 LKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEED 1438
LK+ T ++ + + ++ +P+ S+ ++D+ + +G +
Sbjct: 1349 LKVQTVPQTCDGHKAHTSFQISLTISYTGNRPA-------SNMVIVDVKMVSGFIPLKPT 1401
Query: 1439 LKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEY 1498
+K L T ++ + HV++ + + ++ L F + + VG L PA VY+Y
Sbjct: 1402 VKMLERSSSVSRT--EVSNNHVLIYVEQV-TNQTLSFSFMVLQDIPVGDLKPAIVKVYDY 1458
Query: 1499 HRPDKQCTMFY 1509
+ D+ Y
Sbjct: 1459 YETDESVVAEY 1469
Score = 105 bits (261), Expect = 5e-22
Identities = 143/646 (22%), Positives = 266/646 (41%), Gaps = 50/646 (7%)
Query: 4 LGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKK 63
L +L L+ + E Y++ P + A + + + E + S++S + +
Sbjct: 11 LVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENR 70
Query: 64 FSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDN 123
++ L +E + T+ P+ + + ++ ++ F K + +
Sbjct: 71 SLFTD----LVAEKDLFHCVSFTL-PRISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQ 125
Query: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFID-PEGSEVDMVEEIDHIGI 182
+F+ TDKP+Y P Q+V+ RV S++++ +P L +++ P + + + +
Sbjct: 126 SLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAG 185
Query: 183 ISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKN 242
I+ F + S P G + + + + F V+E+VLP F V ++ I +
Sbjct: 186 INQLSFPLSSEPIQGSYRVVVQTESGGRIQHP--FTVEEFVLPKFEVKVQVP-KIISIMD 242
Query: 243 FKNFEITIKARYFYNKVVTE-ADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
K IT+ Y Y K V A V + + L D++E+ + Q +N +T
Sbjct: 243 EK-VNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQ---LNSNGCITQ 298
Query: 302 DSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEA-EIPGIKYVLSPYKLNLVATP 360
T + +++ E L + + E A I I ++S KL V
Sbjct: 299 QVHTKMLQITNTGFE----MKLRVEARIREEGTDLEVTANRISEITNIVS--KLKFVKVD 352
Query: 361 LFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASF 420
+ GIP+ +V + D GVP+ I VN D + + T + G+A F
Sbjct: 353 SHFRQGIPFFAQVLLVDG-----KGVPIPNKLFFISVN----DANYYSNATTNEQGLAQF 403
Query: 421 VLNLPS-GVTVLEFNVKTDAPDL-------PEENQAREGYRAIAYSSLSQSYLYIDWTDN 472
+N S V L V T P+L E++Q + + A SLS SY++++
Sbjct: 404 SINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQ-HTANRVFSLSGSYIHLEPVAG 462
Query: 473 HKALLVGEHLNIIVTPKSPYIDKITH--YNYLILSKGKIIHFGTR----EKFSDASYQSI 526
E + T + +++ ++YLI++KG I+ GT E ++
Sbjct: 463 TLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFAL 522
Query: 527 NIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQ 586
+ PV ++ P +R+ ++ I+ E+V DS IE N++ + SP P
Sbjct: 523 SFPVESDVAPIARMFIFAIL---PDGEVVGDSEKFEIENCLANKVDLSFSPAQS--PPAS 577
Query: 587 TVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDL 632
L +A S AL AVD +V ++ A+ + V+ L DL
Sbjct: 578 HAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDL 623
>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
Length = 1368
Score = 183 bits (465), Expect = 1e-45
Identities = 190/783 (24%), Positives = 356/783 (45%), Gaps = 90/783 (11%)
Query: 761 SKPEIRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADT-VK 816
S P +R +FPE+W+W + R ++ + +PDS+T+W G IS + G+ + T V+
Sbjct: 605 SSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 664
Query: 817 AKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCV---KMSAVEGICTS-ESPV 872
+ F+ F+ +N+PYSV+RGE+ L+ T++NY + V K + + TS E
Sbjct: 665 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINA 724
Query: 873 IDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPE 932
HQ T V V F + P +G I + + + + + + V E
Sbjct: 725 TGHQQTLL-------VPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAE 777
Query: 933 GVKRESYSGVTLD--PRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA 990
G+++ + LD + T+ K + P + V +E +I ++ G++L
Sbjct: 778 GIEKSYSQSILLDLTDNRLQSTL---KTLSFSFPPNTVTGSERVQITAI-----GDVLGP 829
Query: 991 VLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLK 1050
++ G+ L +P G E +++ P Y+ YL +K++L LK
Sbjct: 830 SIN--GLASLIRMPYGCGEQNMINFAPNIYILDYLT--------------KKKQLTDNLK 873
Query: 1051 EGMLSIMS--------YRNADYSYSVWKG--GSASTWLTAFALRVLGQVNKYVEQNQNSI 1100
E LS M Y+ D S+S + S STWL+AF LR + + Y++ +QN +
Sbjct: 874 EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVL 933
Query: 1101 CNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICP 1160
+ WL + +Q NG F + + +LQG ++ + LTA+ V + P
Sbjct: 934 HRTYTWL-KGHQKSNGEFWDPGRVIHSELQG-----GNKSPVTLTAYIVTSLLGYRKYQP 987
Query: 1161 LVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKG 1220
+ + ++ ++ E + +TLA+ YALS P+ + ++ L A +G
Sbjct: 988 NIDVQESIHFLES---EFSRGISDNYTLALITYALS--SVGSPKAKEALNMLTWRAEQEG 1042
Query: 1221 NPPIYRFWKDNLQHKDSSVPNTGTARM--VETTAYALLTSLNLKDINYVNPVIKWLSEEQ 1278
+FW + +S + ++ R +E AYALL+ + P+++WLS ++
Sbjct: 1043 G---MQFWVSS----ESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQR 1095
Query: 1279 RYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKM-TDKNFLGRP 1337
GGF STQDT A++ L+E++ L+ R ++ + V+ + + + T L +
Sbjct: 1096 NSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQT 1155
Query: 1338 VEVLLNDDLIV---STGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGY 1394
E+ + V + GFG + ++V V + +S S + + D++ +
Sbjct: 1156 AELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQ-EAFDLDVAVKENK 1214
Query: 1395 GNSDYKRIVACASYK-PSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDY 1453
+ ++ + C S+ P R S A+M+++L +G E + +L E V ++ D+
Sbjct: 1215 DDLNHVDLNVCTSFSGPGR------SGMALMEVNLLSGFMVPSEAI-SLSETVKKVEYDH 1267
Query: 1454 QIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSN 1513
G + L L+S+ + F CV F+V A+ ++ +Y+ P +Q Y+ S
Sbjct: 1268 ----GKLNLYLDSVNETQF-CVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN-SE 1321
Query: 1514 IKI 1516
+K+
Sbjct: 1322 VKL 1324
Score = 99.4 bits (246), Expect = 3e-20
Identities = 128/512 (25%), Positives = 225/512 (43%), Gaps = 54/512 (10%)
Query: 165 DPEGSEVDM-VEEIDHIGIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYV 223
DP+ + + + + +G+IS F++ S+P G W+I+ + + T F+V EYV
Sbjct: 93 DPKSNLIQQWLSQQSDLGVIS-KTFQLSSHPILGDWSIQVQVNDQ---TYYQSFQVSEYV 148
Query: 224 LPHFSVSIE-PEYNFIGYKNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEM 282
LP F V+++ P Y + N K+ TI A+Y Y K V + DV +TF + +K +
Sbjct: 149 LPKFEVTLQTPLYCSM---NSKHLNGTITAKYTYGKPV-KGDVTLTF-LPLSFWGKKKNI 203
Query: 283 MQTAMQNTMLINGIAQVTFDSE------TAVKELSYYSLEDLNNKYLYIAVTVIESTGGF 336
+ T ING A +F+ E + LS Y L+ + + I TV ES G
Sbjct: 204 TK-----TFKINGSANFSFNDEEMKNVMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGI 257
Query: 337 SEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQ--- 393
S + + Y + LKP + + V+V + G +TL +
Sbjct: 258 SRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRA-----DGNQLTLEERRNN 311
Query: 394 ---TIDVNQETSDLDPSKSVTRVDDGVASFVLNLP-SGVTVLEFNVKTDAPDLPEENQAR 449
T+ T S S + + V +P SG +EF + D+ +L +
Sbjct: 312 VVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFL 371
Query: 450 EGYRAIAYSSL--SQSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHYNYLILSKG 507
++A SL S S YI + + VG ++V+ ++ +Y+++S+G
Sbjct: 372 GSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNK----RLKELSYMVVSRG 427
Query: 508 KIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKC 567
+++ G + ++ + P + ++VYYI E E++SD + + ++
Sbjct: 428 QLVAVGKQNS------TMFSLTPENSWTPKACVIVYYI---EDDGEIISDVLKIPVQLVF 478
Query: 568 GNQLQVHLSPDADAYSPGQTVSLNMA-TGMDSWVALAAVDSAVYGVQRGAKKPLERVFQF 626
N+++++ S P + VSL ++ T DS V + AVD +V + +E V
Sbjct: 479 KNKIKLYWS--KVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHE 536
Query: 627 LEKSDLGCGAGGGLNNANVFHLAGLTFLTNAN 658
LE + G G +N+ VF GL LT+AN
Sbjct: 537 LELYNTGYYLGMFMNSFAVFQECGLWVLTDAN 568
>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
Length = 1445
Score = 183 bits (465), Expect = 1e-45
Identities = 190/783 (24%), Positives = 356/783 (45%), Gaps = 90/783 (11%)
Query: 761 SKPEIRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADT-VK 816
S P +R +FPE+W+W + R ++ + +PDS+T+W G IS + G+ + T V+
Sbjct: 682 SSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
Query: 817 AKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCV---KMSAVEGICTS-ESPV 872
+ F+ F+ +N+PYSV+RGE+ L+ T++NY + V K + + TS E
Sbjct: 742 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINA 801
Query: 873 IDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPE 932
HQ T V V F + P +G I + + + + + + V E
Sbjct: 802 TGHQQTLL-------VPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAE 854
Query: 933 GVKRESYSGVTLD--PRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA 990
G+++ + LD + T+ K + P + V +E +I ++ G++L
Sbjct: 855 GIEKSYSQSILLDLTDNRLQSTL---KTLSFSFPPNTVTGSERVQITAI-----GDVLGP 906
Query: 991 VLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLK 1050
++ G+ L +P G E +++ P Y+ YL +K++L LK
Sbjct: 907 SIN--GLASLIRMPYGCGEQNMINFAPNIYILDYLT--------------KKKQLTDNLK 950
Query: 1051 EGMLSIMS--------YRNADYSYSVWKG--GSASTWLTAFALRVLGQVNKYVEQNQNSI 1100
E LS M Y+ D S+S + S STWL+AF LR + + Y++ +QN +
Sbjct: 951 EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVL 1010
Query: 1101 CNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICP 1160
+ WL + +Q NG F + + +LQG ++ + LTA+ V + P
Sbjct: 1011 HRTYTWL-KGHQKSNGEFWDPGRVIHSELQG-----GNKSPVTLTAYIVTSLLGYRKYQP 1064
Query: 1161 LVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKG 1220
+ + ++ ++ E + +TLA+ YALS P+ + ++ L A +G
Sbjct: 1065 NIDVQESIHFLES---EFSRGISDNYTLALITYALS--SVGSPKAKEALNMLTWRAEQEG 1119
Query: 1221 NPPIYRFWKDNLQHKDSSVPNTGTARM--VETTAYALLTSLNLKDINYVNPVIKWLSEEQ 1278
+FW + +S + ++ R +E AYALL+ + P+++WLS ++
Sbjct: 1120 G---MQFWVSS----ESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQR 1172
Query: 1279 RYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKM-TDKNFLGRP 1337
GGF STQDT A++ L+E++ L+ R ++ + V+ + + + T L +
Sbjct: 1173 NSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQT 1232
Query: 1338 VEVLLNDDLIV---STGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGY 1394
E+ + V + GFG + ++V V + +S S + + D++ +
Sbjct: 1233 AELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQ-EAFDLDVAVKENK 1291
Query: 1395 GNSDYKRIVACASYK-PSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDY 1453
+ ++ + C S+ P R S A+M+++L +G E + +L E V ++ D+
Sbjct: 1292 DDLNHVDLNVCTSFSGPGR------SGMALMEVNLLSGFMVPSEAI-SLSETVKKVEYDH 1344
Query: 1454 QIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSN 1513
G + L L+S+ + F CV F+V A+ ++ +Y+ P +Q Y+ S
Sbjct: 1345 ----GKLNLYLDSVNETQF-CVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN-SE 1398
Query: 1514 IKI 1516
+K+
Sbjct: 1399 VKL 1401
Score = 140 bits (352), Expect = 1e-32
Identities = 169/660 (25%), Positives = 292/660 (44%), Gaps = 66/660 (10%)
Query: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
++++AP I R G + I +++ E + +++K+ K S + V L +E F+
Sbjct: 28 FLVTAPGIIRPGGNVTIGVELL---EHCPSQVTVKAELLKTASNLTVSV-LEAEGVFEKG 83
Query: 83 AILTIQPKQLPGGQNPVSYVY-LEVVSKH-----FSKSKRMPITYDNGFLFIHTDKPVYT 136
+ T+ LP N +Y L V + FS S R+ +FI TDK +Y
Sbjct: 84 SFKTLTLPSLP--LNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYK 141
Query: 137 PDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDM-VEEIDHIGIISFPDFKIPSNPR 195
P Q VK R+ +L D KP K + DP+ + + + + +G+IS F++ S+P
Sbjct: 142 PKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS-KTFQLSSHPI 200
Query: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARY 254
G W+I+ + + T F+V EYVLP F V+++ P Y + N K+ TI A+Y
Sbjct: 201 LGDWSIQVQVNDQ---TYYQSFQVSEYVLPKFEVTLQTPLYCSM---NSKHLNGTITAKY 254
Query: 255 FYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSE------TAVK 308
Y K V + DV +TF + +K + + T ING A +F+ E +
Sbjct: 255 TYGKPV-KGDVTLTF-LPLSFWGKKKNITK-----TFKINGSANFSFNDEEMKNVMDSSN 307
Query: 309 ELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIP 368
LS Y L+ + + I TV ES G S + + Y + LKP +
Sbjct: 308 GLSEY-LDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLN 365
Query: 369 YPIKVQVKDSLDQLVGGVPVTLNAQ------TIDVNQETSDLDPSKSVTRVDDGVASFVL 422
+ V+V + G +TL + T+ T S S + + V
Sbjct: 366 FTATVKVTRA-----DGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
Query: 423 NLP-SGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSL--SQSYLYIDWTDNHKALLVG 479
+P SG +EF + D+ +L + ++A SL S S YI + + VG
Sbjct: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
Query: 480 EHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSR 539
++V+ ++ +Y+++S+G+++ G + ++ + P +
Sbjct: 481 SPFELVVSGNK----RLKELSYMVVSRGQLVAVGKQNS------TMFSLTPENSWTPKAC 530
Query: 540 LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMA-TGMDS 598
++VYYI E E++SD + + ++ N+++++ S P + VSL ++ T DS
Sbjct: 531 VIVYYI---EDDGEIISDVLKIPVQLVFKNKIKLYWS--KVKAEPSEKVSLRISVTQPDS 585
Query: 599 WVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNAN 658
V + AVD +V + +E V LE + G G +N+ VF GL LT+AN
Sbjct: 586 IVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDAN 645
>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
Length = 1428
Score = 181 bits (459), Expect = 5e-45
Identities = 189/780 (24%), Positives = 353/780 (45%), Gaps = 101/780 (12%)
Query: 761 SKPEIRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADT-VK 816
S P +R +FPE+W+W + R ++ + +PDS+T+W G IS + G+ + T V+
Sbjct: 682 SSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
Query: 817 AKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCV---KMSAVEGICTS-ESPV 872
+ F+ F+ +N+PYSV+RGE+ L+ T++NY + V K + + TS E
Sbjct: 742 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINA 801
Query: 873 IDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPE 932
HQ T V V F + P +G I + + + + + + V E
Sbjct: 802 TGHQQTLL-------VPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAE 854
Query: 933 GVKRESYSGVTLD--PRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA 990
G+++ + LD + T+ K + P + V +E +I ++ G++L
Sbjct: 855 GIEKSYSQSILLDLTDNRLQSTL---KTLSFSFPPNTVTGSERVQITAI-----GDVLGP 906
Query: 991 VLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLK 1050
++ G+ L +P G E +++ P Y+ YL +K++L LK
Sbjct: 907 SIN--GLASLIRMPYGCGEQNMINFAPNIYILDYLT--------------KKKQLTDNLK 950
Query: 1051 EGMLSIMS--------YRNADYSYSVWKG--GSASTWLTAFALRVLGQVNKYVEQNQNSI 1100
E LS M Y+ D S+S + S STWL+AF LR + + Y++ +QN +
Sbjct: 951 EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVL 1010
Query: 1101 CNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICP 1160
+ WL + +Q NG F + + +LQG ++ + LTA+ V + P
Sbjct: 1011 HRTYTWL-KGHQKSNGEFWDPGRVIHSELQG-----GNKSPVTLTAYIVTSLLGYRKYQP 1064
Query: 1161 LVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKG 1220
+ + ++ ++ E + +TLA+ YALS P+ + ++ L A +G
Sbjct: 1065 NIDVQESIHFLES---EFSRGISDNYTLALITYALS--SVGSPKAKEALNMLTWRAEQEG 1119
Query: 1221 NPPIYRFWKDNLQHKDSSVPNTGTARM--VETTAYALLTSLNLKDINYVNPVIKWLSEEQ 1278
+FW + +S + ++ R +E AYALL+ + P+++WLS ++
Sbjct: 1120 G---MQFWVSS----ESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQR 1172
Query: 1279 RYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPV 1338
GGF STQDT A++ L+E++ L+ R ++ + V+ + P+
Sbjct: 1173 NSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS--------------PL 1218
Query: 1339 EVLLNDDLIVS-TGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGYGNS 1397
V+ + +S GFG + ++V V + +S S + + D++ + +
Sbjct: 1219 AVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQ-EAFDLDVAVKENKDDL 1277
Query: 1398 DYKRIVACASYK-PSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIK 1456
++ + C S+ P R S A+M+++L +G E + +L E V ++ D+
Sbjct: 1278 NHVDLNVCTSFSGPGR------SGMALMEVNLLSGFMVPSEAI-SLSETVKKVEYDH--- 1327
Query: 1457 DGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNIKI 1516
G + L L+S+ + F CV F+V A+ ++ +Y+ P +Q Y+ S +K+
Sbjct: 1328 -GKLNLYLDSVNETQF-CVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN-SEVKL 1384
Score = 140 bits (352), Expect = 1e-32
Identities = 169/660 (25%), Positives = 292/660 (44%), Gaps = 66/660 (10%)
Query: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
++++AP I R G + I +++ E + +++K+ K S + V L +E F+
Sbjct: 28 FLVTAPGIIRPGGNVTIGVELL---EHCPSQVTVKAELLKTASNLTVSV-LEAEGVFEKG 83
Query: 83 AILTIQPKQLPGGQNPVSYVY-LEVVSKH-----FSKSKRMPITYDNGFLFIHTDKPVYT 136
+ T+ LP N +Y L V + FS S R+ +FI TDK +Y
Sbjct: 84 SFKTLTLPSLP--LNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYK 141
Query: 137 PDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDM-VEEIDHIGIISFPDFKIPSNPR 195
P Q VK R+ +L D KP K + DP+ + + + + +G+IS F++ S+P
Sbjct: 142 PKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS-KTFQLSSHPI 200
Query: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARY 254
G W+I+ + + T F+V EYVLP F V+++ P Y + N K+ TI A+Y
Sbjct: 201 LGDWSIQVQVNDQ---TYYQSFQVSEYVLPKFEVTLQTPLYCSM---NSKHLNGTITAKY 254
Query: 255 FYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSE------TAVK 308
Y K V + DV +TF + +K + + T ING A +F+ E +
Sbjct: 255 TYGKPV-KGDVTLTF-LPLSFWGKKKNITK-----TFKINGSANFSFNDEEMKNVMDSSN 307
Query: 309 ELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIP 368
LS Y L+ + + I TV ES G S + + Y + LKP +
Sbjct: 308 GLSEY-LDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLN 365
Query: 369 YPIKVQVKDSLDQLVGGVPVTLNAQ------TIDVNQETSDLDPSKSVTRVDDGVASFVL 422
+ V+V + G +TL + T+ T S S + + V
Sbjct: 366 FTATVKVTRA-----DGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
Query: 423 NLP-SGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSL--SQSYLYIDWTDNHKALLVG 479
+P SG +EF + D+ +L + ++A SL S S YI + + VG
Sbjct: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
Query: 480 EHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSR 539
++V+ ++ +Y+++S+G+++ G + ++ + P +
Sbjct: 481 SPFELVVSGNK----RLKELSYMVVSRGQLVAVGKQNS------TMFSLTPENSWTPKAC 530
Query: 540 LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMA-TGMDS 598
++VYYI E E++SD + + ++ N+++++ S P + VSL ++ T DS
Sbjct: 531 VIVYYI---EDDGEIISDVLKIPVQLVFKNKIKLYWS--KVKAEPSEKVSLRISVTQPDS 585
Query: 599 WVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNAN 658
V + AVD +V + +E V LE + G G +N+ VF GL LT+AN
Sbjct: 586 IVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDAN 645
>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
Length = 1454
Score = 181 bits (458), Expect = 7e-45
Identities = 185/782 (23%), Positives = 355/782 (45%), Gaps = 94/782 (12%)
Query: 764 EIRSYFPESWLWEVHLVPR--RKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVF 820
++R YFPE+WLW++ + ++ + +PD++T W+ S + G ++ TV F
Sbjct: 728 QVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGLTAF 787
Query: 821 KDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKS 880
K F+++ +PYSVVRGE +L T++NY ++ C+++ + + E + +++
Sbjct: 788 KPFFVDLTLPYSVVRGESFRLTATIFNY----LKDCIRVQ-TDLAKSHEYQLESWADSQT 842
Query: 881 SKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWF------------------GKEI 922
S C+ + + +H T + L +INF++ T +
Sbjct: 843 SSCL--CADEAKTHHWNITA----VKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDT 896
Query: 923 LVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGL 982
L+K + V PEGV E L P+G + S E +P+D+VP + K ++V G
Sbjct: 897 LIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLE----LPVDIVPDS-TKAYVTVLGD 951
Query: 983 LVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEK 1042
++G L + ++ L +P G E ++ P+ YV YLE +
Sbjct: 952 IMGTAL------QNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAG----------LLT 995
Query: 1043 QKLKKK----LKEGMLSIMSYRNADYSYSVW--KGGSASTWLTAFALRVLGQVNKYVEQN 1096
++++ + L+ G + Y++++ SYS + + G+ +TWLTAF + GQ K++ +
Sbjct: 996 EEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFID 1055
Query: 1097 QNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAF 1156
+I ++L W+ N QL +G + ++G + ++ + LTA+ + +
Sbjct: 1056 PKNIQDALKWMAGN-QLPSGCYANVGNLLHTAMKGGV-----DDEVSLTAYVTAALLEMG 1109
Query: 1157 DICPLVKIDTALIKADNFLLENTLPAQST-FTLAISAYALSLGDKTHPQFRSIVSALKRE 1215
+D ++ L+N+ + + +T A+ AY SL + + ++ L ++
Sbjct: 1110 K-----DVDDPMVSQGLRCLKNSATSTTNLYTQALLAYIFSLAGEMDIR-NILLKQLDQQ 1163
Query: 1216 ALVKGNPPIYRFWKDNLQHKDSSVPNTGTARM-VETTAYALLT-----SLNLKDINYVNP 1269
A++ G +W ++ P + A + VE TAYALL SL K+I
Sbjct: 1164 AIISGES---IYWSQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220
Query: 1270 VIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMT 1329
++ WL++++ GGF STQDT+ A++ L +Y+ +++ V + + +
Sbjct: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVK-STENFQRTFNIQ 1279
Query: 1330 DKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVV-HKTSTSEEVCSFYLKIDTQDIEA 1388
N L + L N + T SG V+V TV+ + + +F L + +I
Sbjct: 1280 SVNRLVFQQDTLPNVPGMY-TLEASGQGCVYVQTVLRYNILPPTNMKTFSLSV---EIGK 1335
Query: 1389 SHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQ 1448
+ + + SY SR S S+ A++++ + +G S E + L++
Sbjct: 1336 ARCEQPTSPRSLTLTIHTSYVGSR----SSSNMAIVEVKMLSGFSPMEGTNQLLLQ--QP 1389
Query: 1449 LFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMF 1508
L + + + L+ + + F I + V L PAT VY+Y+ PD+Q T+
Sbjct: 1390 LVKKVEFGTDTLNIYLDEL-IKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQ 1448
Query: 1509 YS 1510
YS
Sbjct: 1449 YS 1450
Score = 97.1 bits (240), Expect = 1e-19
Identities = 145/626 (23%), Positives = 250/626 (39%), Gaps = 89/626 (14%)
Query: 23 YVISAPKIFRVGASENIVIQVY-GYTEA-FDATISIKSYPDKKFSYSS---GHVHLSSEN 77
Y+++ P + + + + + GY++ F T+ K K YS H+H S
Sbjct: 23 YLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQKLLEYSGLKKRHLHCIS-- 80
Query: 78 KFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKH--FSKSKRMPITYDNGFLFIHTDKPVY 135
+ P GG V+ + + V + F + K++ I F+ TDKP+Y
Sbjct: 81 -------FLVPPPA--GGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFVQTDKPLY 131
Query: 136 TPDQSVKVRVYSLNDDLKPAK-RETVLTFIDPEGSEV-DMVEEIDHIGIISFPDFKIPSN 193
TP Q V R+ +++ + P + +++ DP + + +E + GI+ F++
Sbjct: 132 TPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDL-SFQLAPE 190
Query: 194 PRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVS-IEP-EYNFIGYKNFKNFEITIK 251
G +T+ + F T F V+EYVLP F V +EP E + + ++F + I
Sbjct: 191 AMLGTYTVAVAEGKTFGT-----FSVEEYVLPKFKVEVVEPKELSTVQ----ESFLVKIC 241
Query: 252 ARYFYNK---------VVTEADVYITFGI-REDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
RY Y K V +A+ Y + RE L D + + + + TF
Sbjct: 242 CRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATF 301
Query: 302 DSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPY--KLNLVAT 359
D + Y +N I TV+E G A +SP + T
Sbjct: 302 DL------IGYAYSHQIN-----IVATVVEEGTGVEANAT---QNIYISPQMGSMTFEDT 347
Query: 360 PLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVAS 419
F P P+ K++V+ D + V L V T+ VT ++G+A
Sbjct: 348 SNFYHPNFPFSGKIRVRGHDDSFLKNHLVFL------VIYGTNGTFNQTLVTD-NNGLAP 400
Query: 420 FVLNLPS-GVTVLEFNVKTDAPDLPEENQAREGYRAIAY------SSLSQSYLYIDWTDN 472
F L T + K DL + Y AY S ++S+L I +
Sbjct: 401 FTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNG 460
Query: 473 HKALLVGEHLNIIV----TPKSPYIDKITHYNYLILSKGKII-----HFGTREKFSDASY 523
L G+ ++V P D+ ++Y ++ KG ++ H +++K AS+
Sbjct: 461 --PLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASF 518
Query: 524 QSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYS 583
S+++ T + P L++Y I + +V+D + ++E NQ+ + SP
Sbjct: 519 -SLSLTFTSRLAPDPSLVIYAIF---PSGGVVADKIQFSVEMCFDNQVSLGFSPSQQL-- 572
Query: 584 PGQTVSLNMATGMDSWVALAAVDSAV 609
PG V L + S AL AVD +V
Sbjct: 573 PGAEVELQLQAAPGSLCALRAVDESV 598
>gi|239758130 PREDICTED: similar to complement component 4B (Childo
blood group), partial [Homo sapiens]
Length = 666
Score = 150 bits (378), Expect = 1e-35
Identities = 160/676 (23%), Positives = 283/676 (41%), Gaps = 90/676 (13%)
Query: 1079 TAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEAR 1138
TAF L+VL + V ++ + + WL+ Q D GSF++ S +QG L
Sbjct: 1 TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQAD-GSFQDLSPVIHRSMQGGLV--GN 57
Query: 1139 ENSLYLTAFTVIGIRKAFDIC------PLV-KIDTALIKADNFLLENTLPAQ-STFTLAI 1190
+ ++ LTAF I + + PL +++ ++ KA++FL E AI
Sbjct: 58 DETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAI 117
Query: 1191 SAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTAR---- 1246
+AYAL+L K R + + +Y W + ++V T R
Sbjct: 118 TAYALTL-TKAPADLRGVAHNNLMAMAQETGDNLY--WGSVTGSQSNAVSPTPAPRNPSD 174
Query: 1247 --------MVETTAYALL-TSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGL 1297
+ETTAYALL L+ + WL+ + + GGF STQDT+ A++ L
Sbjct: 175 PMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDAL 234
Query: 1298 TEY---SLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPVEVL--LNDDLIVSTGF 1352
+ Y S ++ L++ + + ++ H ++ ++ G E+ L + V G
Sbjct: 235 SAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVG- 293
Query: 1353 GSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGYGNSDYKR----------- 1401
G+ T+ V + C L+I+ Y N DY+
Sbjct: 294 GNSKGTLKVLRTYNVLDMKNTTCQD-LQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDD 352
Query: 1402 -------IVACASYKPSR-----------EESSSG---------------SSHAVMDISL 1428
+ ++ R EE S S A+ D++L
Sbjct: 353 PDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTL 412
Query: 1429 PTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFL 1488
+G A DL+ L D+ + ++ + HV+L +S+P+S CV F + VG +
Sbjct: 413 LSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRE-CVGFEAVQEVPVGLV 471
Query: 1489 SPATFTVYEYHRPDKQCTMFYS--TSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAE 1546
PA+ T+Y+Y+ P+++C++FY + + + +C C+C E C + + L+ + E
Sbjct: 472 QPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDE 531
Query: 1547 T--RKQTAC-KPEIAYAYKVSITSITVENVFVKYKATLLDI-YKTGEAVAEKDSEITFIK 1602
R + AC P + Y ++V + F ++ + + + T + A + F+
Sbjct: 532 DGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLV 591
Query: 1603 KVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSC--QAF 1660
+ +C L G++YLIMG + Y+ Y LDS +WIE P + C S +A
Sbjct: 592 RASC-RLRLEPGKEYLIMGLDG--ATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAA 648
Query: 1661 LANLDEFAEDIFLNGC 1676
A L++F ++ GC
Sbjct: 649 CAQLNDFLQEYGTQGC 664
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 145 bits (367), Expect = 2e-34
Identities = 156/617 (25%), Positives = 262/617 (42%), Gaps = 74/617 (11%)
Query: 954 SRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELM 1013
S + F +P +P +E ++G+++ L+ +N L LP G E ++
Sbjct: 1145 SYSEAFTLGVPHGAIPGSE-----RATASIIGDVMGPTLNH--LNNLLRLPFGCGEQNMI 1197
Query: 1014 SVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVW--KG 1071
P +V YL+ + P +E++ L +G ++Y+ D SYS + +
Sbjct: 1198 HFAPNVFVLKYLQKTQQLS-----PEVERETTDY-LVQGYQRQLTYKRQDGSYSAFGERD 1251
Query: 1072 GSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQG 1131
S S WLTAF L+ Q ++ + + + W+++ Q D GSF + +QG
Sbjct: 1252 ASGSMWLTAFVLKSFAQARSFIFVDPRELAAAKSWIIQQQQAD-GSFLAVGRVLNKDIQG 1310
Query: 1132 TLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAIS 1191
+ ++ LTA+ V+ + + + T KA +FL A ++ A++
Sbjct: 1311 GI-----HGTVPLTAYVVVALLETGTASEEERGSTD--KARHFLESAAPLAMDPYSCALT 1363
Query: 1192 AYALSLGDKTHPQFRSIVSALKREALVKGNPPIYRF---W---KDNLQHKDSSVPNTGTA 1245
YAL+L P + L+ A+++ + W K V + +
Sbjct: 1364 TYALTL--LRSPAAPEALRKLRSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVS 1421
Query: 1246 RMVETTAYALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVK 1305
VE TAYALLT L D+ PV+KWLS+++ GGF STQDT A++ L EY++L
Sbjct: 1422 AEVEMTAYALLTYTLLGDVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSY 1481
Query: 1306 QLRLSMDI-----DVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVST-GFGSGLATV 1359
+++ + ++ Y+ LH T++ L L L VS G G L +
Sbjct: 1482 AGGINLTVSLASTNLDYQETFELHR---TNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQI 1538
Query: 1360 HVTTVVHKTSTSEEVCSFYLKIDTQDIE------------ASHYRG-------------Y 1394
VT V +F L + Q+ E A RG
Sbjct: 1539 DVTYNVPDPVAKP---AFQLLVSLQEPEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQ 1595
Query: 1395 GNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQ 1454
+ +YK ++ +R + S+ AV+++ L +G A+ E L+ L+ Y+
Sbjct: 1596 HHQEYKVMLEVC----TRWLHAGSSNMAVLEVPLLSGFRADIESLEQLLLDKHMGMKRYE 1651
Query: 1455 IKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFY--STS 1512
+ V+ + IPS CVRFR VG S +VY+Y+ P + T FY ST
Sbjct: 1652 VAGRRVLFYFDEIPSRCLTCVRFRALRECVVGRTSALPVSVYDYYEPAFEATRFYNVSTH 1711
Query: 1513 NIKIQKVCEGAACKCVE 1529
+ +++C G AC VE
Sbjct: 1712 SPLARELCAGPACNEVE 1728
Score = 139 bits (349), Expect = 3e-32
Identities = 198/919 (21%), Positives = 356/919 (38%), Gaps = 172/919 (18%)
Query: 19 QEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFS-----YSSGHVHL 73
Q Y+I+AP +FR G E I + ++ + + + G + L
Sbjct: 76 QAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQAQLVAQGEPVVQSQGAILDKGTIKL 135
Query: 74 SSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKP 133
+ A+L + + + P+ F + + +FI TDKP
Sbjct: 136 KVPTGLRGQALLKVWGRGWQAEEGPL-----------FHNQTSVTVDGRGASVFIQTDKP 184
Query: 134 VYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHI--GIISFPDFKIP 191
VY P V + +++++ +L+P + +DP GS + + GI + F +
Sbjct: 185 VYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWRHLKPFCCGITNM-SFPLS 243
Query: 192 SNPRYGMWTIKAKYKEDFSTTGTAY---FEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEI 248
P G W I + + G AY FEV++YVLP F + I+P +
Sbjct: 244 DQPVLGEWFIFVEMQ------GHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETG-- 295
Query: 249 TIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVK 308
T++ARY + K V A + I + + E+ + ++ T ++ + D + V+
Sbjct: 296 TVRARYTFGKPVAGA-LMINMTVN-GVGYYSHEVGRPVLRTTKILG-----SRDFDICVR 348
Query: 309 ELSYYSLED--LNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPG 366
++ + + ++ VT ++ + + + P ++ L + + F KPG
Sbjct: 349 DMIPADVPEHFRGRVSIWAMVTSVDGSQQVAFDDSTP-VQRQLVDIRYSKDTRKQF-KPG 406
Query: 367 IPYPIKVQVKDSLDQLVGGVPVTLNAQ-TIDVNQETSDLDPSKSVTRVDDGVASFVLNLP 425
+ Y KV++ GV V + A+ T N TS++ + + + + ++P
Sbjct: 407 LAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVGFE------IPSIP 460
Query: 426 SGVTVLEFNVKTDAPD-LPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNI 484
+ + K A + P Q Y ++ S S S Y+ L VGE
Sbjct: 461 TSAQHVWLETKVMALNGKPVGAQYLPSYLSLG-SWYSPSQCYLQLQPPSHPLQVGEEAYF 519
Query: 485 IVTPKSPYIDKITHYNYLILSKGKIIHFGTR----------------------------- 515
V P T Y Y + ++G I+ G +
Sbjct: 520 SVKSTCPC--NFTLY-YEVAARGNIVLSGQQPAHTTQQRSKRAAPALEKPIRLTHLSETE 576
Query: 516 -----EKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQ 570
E D S+++ VT +MVP RLLV+Y+ + E V+DS+ +E NQ
Sbjct: 577 PPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYV---RENGEGVADSLQFAVETFFENQ 633
Query: 571 LQVHLSPDADAYSPGQTVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLERVFQFLEKS 630
+ V S A+ PG+ V L + S V +AAVD +VY ++ G + +V F E
Sbjct: 634 VSVTYS--ANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQV--FQELE 689
Query: 631 DLGCGAGGGLNNAN-VFHLAGLTFLTNANADDSQENDEPCKEILRPRRTLQKKIEEIAAK 689
D G++ + F AGL T Q++
Sbjct: 690 DYDVSDSFGVSREDGPFWWAGL--------------------------TAQRRRRSSVFP 723
Query: 690 YKHSVVKKCCYDGACVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQL 749
+ + K + AFTE +V R +++H+ Q
Sbjct: 724 WPWGITKDSGF--------------------------AFTETGLVVMTDRVSLNHR--QD 755
Query: 750 GRLHMKTLLPVSKPEI-------------------RSYFPESWLWEVHLVPRRK---QLQ 787
G L+ +P +P R++FPE+W+W + L
Sbjct: 756 GGLYTDEAVPAFQPHTGSLVAVAPSRHPPRTEKRKRTFFPETWIWHCLNISDPSGEGTLS 815
Query: 788 FALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVY 846
+PDS+T+W + V +S + G+ +A+ K FK F++ +P ++RGEQ+++ +VY
Sbjct: 816 VKVPDSITSWVGEAVALSTSQGLGIAEPSLLKTFKPFFVDFMLPALIIRGEQVKIPLSVY 875
Query: 847 NYRTSGMQFCVKMSAVEGI 865
NY + + +K+S +GI
Sbjct: 876 NYMGTCAEVYMKLSVPKGI 894
>gi|169214179 PREDICTED: similar to complement component 3 [Homo
sapiens]
Length = 390
Score = 142 bits (357), Expect = 4e-33
Identities = 96/383 (25%), Positives = 173/383 (45%), Gaps = 22/383 (5%)
Query: 1305 KQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTV 1364
++L L + + + + H + L R E N+ V T G G T+ V T+
Sbjct: 17 QELNLDVSLQLPSRSSKITHRIHWESASLL-RSEETKENEGFTV-TAEGKGQGTLSVVTM 74
Query: 1365 VHKTSTSEEVCS-FYLKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAV 1423
H + + C+ F LK+ + + R + + C Y+ ++ + S +
Sbjct: 75 YHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMS-----I 129
Query: 1424 MDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGH-----VILQLNSIPSSDFLCVRFR 1478
+DIS+ TG + + +DLK L GVD+ + Y++ +I+ L+ + S+ C+ F+
Sbjct: 130 LDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFK 189
Query: 1479 IFELFEVGFLSPATFTVYEYHRPDKQCTMFY--STSNIKIQKVCEGAACKCVEADCGQMQ 1536
+ + F V + P VY Y+ ++ CT FY + K+ K+C C+C E +C
Sbjct: 190 VHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENC--FI 247
Query: 1537 EELDLTISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDS 1596
++ D ++ E R AC+P + Y YK + + + N F +Y + K+G +
Sbjct: 248 QKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQ 307
Query: 1597 EITFIKKVTCTNA-ELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTC- 1654
+ TFI + C A +L + + YL+ G + + YI D TW+E+WP + C
Sbjct: 308 QRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKD--TWVEHWPEEDECQ 365
Query: 1655 -SSCQAFLANLDEFAEDIFLNGC 1676
Q +L F E + + GC
Sbjct: 366 DEENQKQCQDLGAFTESMVVFGC 388
>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 1394
Score = 134 bits (337), Expect = 7e-31
Identities = 146/557 (26%), Positives = 255/557 (45%), Gaps = 80/557 (14%)
Query: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
+R+ FPE+W+W++ V L F +PD++T WE G ++ + G ++ T +V +
Sbjct: 719 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778
Query: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSS 881
F+E+ P+SVV+ EQ L ++Y + CV++S + I+ S
Sbjct: 779 PFFIEIASPFSVVQNEQFDLIVNAFSY----LNTCVEISVQVEESQNYEANINTWKINGS 834
Query: 882 KCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLET-----------------WFGKEILV 924
+ + + G +++ +T++P ++G NI E+ W K+ +V
Sbjct: 835 EVI--QAGGRKTNI--WTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNW--KDTVV 888
Query: 925 KTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGL-- 982
K+ V PEG+++E + G + K+ +P D+V S +G
Sbjct: 889 KSFLVEPEGIEKERTQSFLICTEGAKAS----KQGVLDLPNDVVEG-------SARGFFT 937
Query: 983 LVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEK 1042
+VG+IL L+ + + +L +P G E + YV YL++ ++ L E+
Sbjct: 938 VVGDILG--LAMQNLVVL-QMPYGGGEQNAALLASDTYVLDYLKS--------TEQLTEE 986
Query: 1043 QKLKK--KLKEGMLSIMSYRNADYSYSVW--KGGSASTWLTAFALRVLGQVNKYVEQNQN 1098
+ K L G +S++N+D SYSV+ + S WL+A + L ++ K+V ++N
Sbjct: 987 VQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDEN 1046
Query: 1099 SICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDI 1158
+L+WL + Q +G FK + Q +G E + LTA+ V+G+ F
Sbjct: 1047 VQKQTLIWL-SSQQKTSGCFKNDGQLFNHAWEG-----GDEEDISLTAY-VVGM---FFE 1096
Query: 1159 CPLVKIDTALIKADNFLLENTLPAQST--FTLAISAYALSLGDKTHPQFRSIVSALKREA 1216
L AL A F LE L + T + AI AYA +L K Q S++ L + A
Sbjct: 1097 AGLNSTFPALRNA-LFCLEAALDSGVTNGYNHAILAYAFALAGK-EKQVESLLQTLDQSA 1154
Query: 1217 LVKGNPPIYRFWKDNLQHKDSSVPN---TGTARMVETTAYALLTSLNLK--DINYVNPVI 1271
K N IY W+ + K P+ + E + Y LL ++ K D+ Y + ++
Sbjct: 1155 -TKLNNVIY--WERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIV 1211
Query: 1272 KWLSEEQRYGGGFYSTQ 1288
+WL+++ GGF S Q
Sbjct: 1212 QWLAQQMNSHGGFSSNQ 1228
Score = 61.2 bits (147), Expect = 8e-09
Identities = 125/632 (19%), Positives = 248/632 (39%), Gaps = 69/632 (10%)
Query: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
YV+ P + + G+ + Q++ TE+ T+S+ +Y + EN +
Sbjct: 13 YVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSL--------NYGEVQTKIFEENVTGEN 64
Query: 83 AILTIQPKQLPGGQNPVSYVYLEV--VSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQS 140
I + +P++++ + + + + + I +F+ TDKP Y P Q
Sbjct: 65 FFKCISFEVPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQK 124
Query: 141 VKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWT 200
+ D + T DP+ + + + + I+ F++ S P +G +
Sbjct: 125 DVNGIAQFFLDTYTFTYPNI-TLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYW 183
Query: 201 IKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARYFYNKV 259
I K + T T F VK YVLP F V++ P+ I + F++ + A+Y + +
Sbjct: 184 IVVK--RNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTI---SDDEFQVDVCAKYTFGQP 238
Query: 260 V---TEADVYITFGIREDLKDDQKEMMQTAMQNTMLING-IAQVTFDSETAVKELSYYSL 315
V T+ V + + + + E+ + + L NG ++Q+ T V +L L
Sbjct: 239 VQGKTQIRVCREYFSSSNCEKNDNEICEQFI--AQLENGCVSQIV---NTKVFQLYRSGL 293
Query: 316 EDLNNKYLYIAVTVIE-STGGFSEE-AEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKV 373
++AV V E TG + + +E + +N F + GI Y +
Sbjct: 294 ----FMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTL 349
Query: 374 QVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEF 433
+ D VP+ +++N E + T ++G A F ++ S + EF
Sbjct: 350 KFSDP-----NNVPMVNKLLQLELNDEFIG-----NYTTDENGEAQFSID-TSDIFDPEF 398
Query: 434 NVKTD--------APDLPEENQAREGYRAIAYSSLSQSYLYI-----DWTDNHKALLVGE 480
N+K P + + S + S+L I NH+ ++
Sbjct: 399 NLKATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVT-- 456
Query: 481 HLNIIVTPKSPYIDKITHYNYLIL---SKGKIIHFGTREKFSDASYQSINIP--VTQNMV 535
++ + ++ D + YL+ G H + A + + P ++ ++
Sbjct: 457 -VHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLA 515
Query: 536 PSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
P++ L VY T + E+V+DSV +++ +++ + S + PG SL +
Sbjct: 516 PAAVLFVY---TLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGL--PGSNASLYLQAA 570
Query: 596 MDSWVALAAVDSAVYGVQRGAKKPLERVFQFL 627
+ AL AVD V ++ + E V+ +
Sbjct: 571 PVLFCALGAVDGNVLLLKSEQQLSAESVYNMV 602
>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
Length = 1353
Score = 134 bits (337), Expect = 7e-31
Identities = 144/564 (25%), Positives = 250/564 (44%), Gaps = 94/564 (16%)
Query: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
+R+ FPE+W+W++ V L F +PD++T WE G ++ + G ++ T +V +
Sbjct: 670 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 729
Query: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKM-------SAVEGICTSESPVID 874
F+E+ P+SVV+ EQ L V++YR + ++ V++ + + + + S VI
Sbjct: 730 PFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKINGSEVIQ 789
Query: 875 HQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLET-----------------W 917
G K++ +T++P ++G NI E+ W
Sbjct: 790 AGGRKTN---------------VWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNW 834
Query: 918 FGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRIL 977
K+ +V++ V PEG+++E + G + K+ +P D+V
Sbjct: 835 --KDTVVQSFLVEPEGIEKERTQSFLICTEGAKAS----KQGVLDLPNDVVEG------- 881
Query: 978 SVKGL--LVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFH 1035
S +G +VG+IL L ++ +P GS E + YV YL++
Sbjct: 882 SARGFFTVVGDILGLALQN---LVVLQMPYGSGEQNAALLASDTYVLDYLKS-------- 930
Query: 1036 SDPLIEKQKLKK--KLKEGMLSIMSYRNADYSYSVW--KGGSASTWLTAFALRVLGQVNK 1091
++ L E+ + K L G +S++N+D SYSV+ + S L+A + L ++ K
Sbjct: 931 TEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQSQKGSIXLSALTFKTLERMKK 990
Query: 1092 YVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIG 1151
YV ++N +L+WL + Q +G FK + Q +G E + LTA+ V
Sbjct: 991 YVFIDENVQKQTLIWL-SSQQKTSGCFKNDGQLFNHAWEG-----GDEEDISLTAYVVGM 1044
Query: 1152 IRKAFDICPLVKIDTALIKADNFLLENTLPAQST--FTLAISAYALSLGDKTHPQFRSIV 1209
+A + AL F LE L + T + AI AYA +L K Q S++
Sbjct: 1045 FFEAGLNFTFPALRNAL-----FCLEAALDSGVTNGYNHAILAYAFALAGK-EKQVESLL 1098
Query: 1210 SALKREALVKGNPPIYRFWKDNLQHKDSSVPN---TGTARMVETTAYALLTSLNLK--DI 1264
L + A K N IY W+ + K P+ + E + Y LL ++ K D+
Sbjct: 1099 QTLDQSA-PKLNNVIY--WERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDL 1155
Query: 1265 NYVNPVIKWLSEEQRYGGGFYSTQ 1288
Y + +++WL++ GGF S Q
Sbjct: 1156 TYASKIVQWLAQRMNSHGGFSSNQ 1179
Score = 51.6 bits (122), Expect = 6e-06
Identities = 118/572 (20%), Positives = 229/572 (40%), Gaps = 64/572 (11%)
Query: 83 AILTIQPKQLPGGQNPVSYVYLEV--VSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQS 140
+IL + P+ +P++++ + + + + + I +F+ TDKP Y P Q
Sbjct: 19 SILNVVPQ---ARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQK 75
Query: 141 VKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWT 200
+ D + T DP+ + + + + I+ F++ S P +G +
Sbjct: 76 DVNGIAQFFLDTYTFTYPNI-TLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGDYW 134
Query: 201 IKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARYFYNKV 259
I K + T T F VK YVLP F V++ P+ I + F++ + A+Y + +
Sbjct: 135 IVVK--RNSRETVTHQFAVKRYVLPKFEVTVNAPQTVTI---SDDEFQVDVCAKYNFGQP 189
Query: 260 V---TEADVYITFGIREDLKDDQKEMMQTAMQNTMLING-IAQVTFDSETAVKELSYYSL 315
V T+ V + + + ++ E+ + + L NG ++Q+ T V +L L
Sbjct: 190 VQGETQIRVCREYFSSSNCEKNENEICEQFI--AQLENGCVSQIV---NTKVFQLYRSGL 244
Query: 316 EDLNNKYLYIAVTVIESTGG--FSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKV 373
++AV V ES G F + +E + +N F + GI Y +
Sbjct: 245 ----FMTFHVAVIVTESGTGNYFMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTL 300
Query: 374 QVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEF 433
+ D VP+ +++N E + T ++G A F ++ S + EF
Sbjct: 301 KFSDP-----NNVPMVNKLLQLELNDEFIG-----NYTTDENGEAQFSID-TSDIFDPEF 349
Query: 434 NVKTD--------APDLPEENQAREGYRAIAYSSLSQSYLYI----DWTDNHKALLVGEH 481
N+K P + + S + S+L I + ++ +V H
Sbjct: 350 NLKATYVRPESCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNQQKVVTVH 409
Query: 482 LNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSIN------IPVTQNMV 535
++ ++ D + YL+ +F R S Y + N I ++ ++
Sbjct: 410 YSL--NSEAYEDDSNVKFFYLVSLSHDSGNFQHRIS-SSPIYTAWNGNFSFPISISADLA 466
Query: 536 PSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
P++ L VY T + E+V+DSV +++ +++ + S + PG SL +
Sbjct: 467 PAAVLFVY---TLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGL--PGSNASLCLQAA 521
Query: 596 MDSWVALAAVDSAVYGVQRGAKKPLERVFQFL 627
+ AL AVD V ++ + E V+ +
Sbjct: 522 PVLFCALRAVDRNVLLLKSEQQLSAESVYNMV 553
>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
blood group) [Homo sapiens]
Length = 270
Score = 105 bits (261), Expect = 5e-22
Identities = 65/217 (29%), Positives = 112/217 (51%), Gaps = 10/217 (4%)
Query: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGII 183
G LF+ TD+P+Y P Q V+ RV++L+ ++P+ +T+ ++ +E+ I
Sbjct: 59 GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPST-DTITVMVENSHGLRVRKKEVYMPSSI 117
Query: 184 SFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEP--EYNFIGYK 241
DF IP G W I A++ + + + FEVK+YVLP+F V I P Y
Sbjct: 118 FQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 177
Query: 242 NFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
+ ++ I+ARY Y K V + Y+ FG+ ++ D +K + T L+NG + ++
Sbjct: 178 HLDEMQLDIQARYIYGKPV-QGVAYVRFGLLDE--DGKKTFFRGLESQTKLVNGQSHISL 234
Query: 302 ---DSETAVKELSYYSLEDLNNKYLYIAVTVIESTGG 335
+ + A+++L+ + DL LY+A +IE GG
Sbjct: 235 SKAEFQDALEKLN-MGITDLQGLRLYVAAAIIEYPGG 270
>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
Length = 750
Score = 73.6 bits (179), Expect = 2e-12
Identities = 69/285 (24%), Positives = 130/285 (45%), Gaps = 46/285 (16%)
Query: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
+R+ FPE+W+W++ V L F +PD++T WE G ++ + G ++ T +V +
Sbjct: 362 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 421
Query: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSS 881
F+E+ P+SVV+ EQ L ++Y + CV++S + I+ S
Sbjct: 422 PFFIEIASPFSVVQNEQFDLIVNAFSY----LNTCVEISVQVEESQNYEANINTWKINGS 477
Query: 882 KCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLET-----------------WFGKEILV 924
+ + + G +++ +T++P ++G NI E+ W K+ +V
Sbjct: 478 EVI--QAGGRKTNI--WTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNW--KDTVV 531
Query: 925 KTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGL-- 982
K+ V PEG+++E + G + K+ +P D+V S +G
Sbjct: 532 KSFLVEPEGIEKERTQSFLICTEGAKAS----KQGVLDLPNDVVEG-------SARGFFT 580
Query: 983 LVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLET 1027
+VG+IL L+ + + +L +P G E + YV YL++
Sbjct: 581 VVGDILG--LAMQNLVVL-QMPYGGGEQNAALLASDTYVLDYLKS 622
>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 278
Score = 64.3 bits (155), Expect = 9e-10
Identities = 31/98 (31%), Positives = 58/98 (59%), Gaps = 3/98 (3%)
Query: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
+R+ FPE+W+W++ V L F +PD++T WE G ++ + G ++ T +V +
Sbjct: 67 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 126
Query: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKM 859
F+E+ P+SVV+ EQ L V++YR + ++ V++
Sbjct: 127 PFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQV 164
>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
Length = 189
Score = 44.7 bits (104), Expect = 8e-04
Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 11/122 (9%)
Query: 1174 FLLENTLPAQST--FTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDN 1231
F LE L + T + AI AYA +L K Q S++ L + A K N IY W+
Sbjct: 55 FCLEAALDSGVTNGYNHAILAYAFALAGK-EKQVESLLQTLDQSA-TKLNNVIY--WERE 110
Query: 1232 LQHKDSSVPNT---GTARMVETTAYALLTSLNLK--DINYVNPVIKWLSEEQRYGGGFYS 1286
+ K P+ + E + Y LL ++ K D+ Y + +++WL+++ GGF S
Sbjct: 111 RKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQMNSHGGFSS 170
Query: 1287 TQ 1288
Q
Sbjct: 171 NQ 172
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 36.2 bits (82), Expect = 0.27
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 1126 PIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLP--AQ 1183
P+ QGT R N L I FD+ P + L+ N EN P ++
Sbjct: 852 PVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK 911
Query: 1184 STFTLAISA-YALSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSV 1239
+TF L + YA+ +H QF ++ + E + + ++R+ +NL +D V
Sbjct: 912 TTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEE-KESHVAMHRYQVNNLGQRDLPV 967
>gi|95007030 lines homolog 1 [Homo sapiens]
Length = 757
Score = 33.5 bits (75), Expect = 1.8
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIK 251
Y +WT+ A KE F + + E+ + L HF E YN + ++F+N T K
Sbjct: 189 YCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSK 244
>gi|95007028 lines homolog 1 [Homo sapiens]
Length = 757
Score = 33.5 bits (75), Expect = 1.8
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIK 251
Y +WT+ A KE F + + E+ + L HF E YN + ++F+N T K
Sbjct: 189 YCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSK 244
>gi|95007024 lines homolog 1 [Homo sapiens]
Length = 757
Score = 33.5 bits (75), Expect = 1.8
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIK 251
Y +WT+ A KE F + + E+ + L HF E YN + ++F+N T K
Sbjct: 189 YCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSK 244
>gi|95007026 lines homolog 1 [Homo sapiens]
Length = 757
Score = 33.5 bits (75), Expect = 1.8
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIK 251
Y +WT+ A KE F + + E+ + L HF E YN + ++F+N T K
Sbjct: 189 YCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSK 244
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor [Homo
sapiens]
Length = 329
Score = 32.7 bits (73), Expect = 3.0
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 13/80 (16%)
Query: 1597 EITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSS 1656
E++ I K+T TN + K + +KYN +R D+ TW + P DT +
Sbjct: 235 ELSSILKLTWTNPSI----------KSVIILKYNIQYR---TKDASTWSQIPPEDTASTR 281
Query: 1657 CQAFLANLDEFAEDIFLNGC 1676
+ +L F E +F C
Sbjct: 282 SSFTVQDLKPFTEYVFRIRC 301
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor [Homo
sapiens]
Length = 918
Score = 32.7 bits (73), Expect = 3.0
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 13/80 (16%)
Query: 1597 EITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSS 1656
E++ I K+T TN + K + +KYN +R D+ TW + P DT +
Sbjct: 235 ELSSILKLTWTNPSI----------KSVIILKYNIQYR---TKDASTWSQIPPEDTASTR 281
Query: 1657 CQAFLANLDEFAEDIFLNGC 1676
+ +L F E +F C
Sbjct: 282 SSFTVQDLKPFTEYVFRIRC 301
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 32.7 bits (73), Expect = 3.0
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 1126 PIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLP--AQ 1183
P+ QGT R N L I FD+ P + L+ N EN P ++
Sbjct: 101 PVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK 160
Query: 1184 STFTLAISA-YALSLGDKTHPQFRSIVSALKRE 1215
+TF L + YA+ +H QF ++ + E
Sbjct: 161 TTFQLELPVKYAVYTVVSSHEQFTKYLNFSESE 193
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,316,285
Number of Sequences: 37866
Number of extensions: 2674394
Number of successful extensions: 6213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 5976
Number of HSP's gapped (non-prelim): 59
length of query: 1676
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1560
effective length of database: 13,855,062
effective search space: 21613896720
effective search space used: 21613896720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.