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Search of human proteins with 37594469
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2
[Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2 [... 672 0.0
gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1 [... 670 0.0
gi|194097323 mitochondrial short-chain enoyl-coenzyme A hydratas... 96 5e-20
gi|4502327 AU RNA binding protein/enoyl-Coenzyme A hydratase pre... 71 2e-12
gi|68989263 enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A... 70 3e-12
gi|70995211 peroxisomal enoyl-coenzyme A hydratase-like protein ... 67 2e-11
gi|20127408 mitochondrial trifunctional protein, alpha subunit p... 64 2e-10
gi|31542718 enoyl Coenzyme A hydratase domain containing 3 [Homo... 55 9e-08
gi|157694516 enoyl Coenzyme A hydratase domain containing 1 isof... 53 4e-07
gi|213417737 enoyl Coenzyme A hydratase domain containing 1 isof... 53 4e-07
gi|4757966 Y chromosome chromodomain protein 1, telomeric isofor... 49 8e-06
gi|25453481 Y chromosome chromodomain protein 1, telomeric isofo... 49 8e-06
gi|51538581 chromodomain protein, Y-linked, 1B isoform b [Homo s... 49 8e-06
gi|51538573 chromodomain protein, Y-linked, 1B isoform a [Homo s... 49 8e-06
gi|150378541 enoyl Coenzyme A hydratase domain containing 2 [Hom... 47 2e-05
gi|49355787 Y chromosome chromodomain protein 2B [Homo sapiens] 45 7e-05
gi|4757968 Y chromosome chromodomain protein 2A [Homo sapiens] 45 7e-05
gi|45643119 peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 [Hom... 41 0.001
gi|221307494 chromodomain protein, Y chromosome-like isoform a [... 40 0.003
gi|221136756 chromodomain protein, Y chromosome-like isoform d [... 40 0.003
gi|221136753 chromodomain protein, Y chromosome-like isoform d [... 40 0.003
gi|157694520 enoyl Coenzyme A hydratase domain containing 1 isof... 39 0.007
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 36 0.043
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 36 0.043
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 36 0.056
gi|111955063 GTP-binding protein 10 isoform 1 [Homo sapiens] 32 0.81
gi|50593027 enoyl Coenzyme A hydratase domain containing 1 isofo... 31 1.4
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 31 1.8
gi|19923599 calmin [Homo sapiens] 30 3.1
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 30 4.0
>gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2
[Homo sapiens]
Length = 338
Score = 672 bits (1734), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNAL 60
MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNAL
Sbjct: 1 MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNAL 60
Query: 61 TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE 120
TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE
Sbjct: 61 TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE 120
Query: 121 EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG 180
EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG
Sbjct: 121 EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG 180
Query: 181 GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENI 240
GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENI
Sbjct: 181 GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENI 240
Query: 241 ASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVIN 300
ASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVIN
Sbjct: 241 ASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVIN 300
Query: 301 KMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMF 338
KMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMF
Sbjct: 301 KMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMF 338
>gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1
[Homo sapiens]
Length = 386
Score = 670 bits (1728), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNAL 60
MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNAL
Sbjct: 1 MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNAL 60
Query: 61 TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE 120
TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE
Sbjct: 61 TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE 120
Query: 121 EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG 180
EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG
Sbjct: 121 EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG 180
Query: 181 GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENI 240
GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENI
Sbjct: 181 GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENI 240
Query: 241 ASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVIN 300
ASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVIN
Sbjct: 241 ASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVIN 300
Query: 301 KMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 337
KMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM
Sbjct: 301 KMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 337
>gi|194097323 mitochondrial short-chain enoyl-coenzyme A hydratase 1
precursor [Homo sapiens]
Length = 290
Score = 95.9 bits (237), Expect = 5e-20
Identities = 76/236 (32%), Positives = 117/236 (49%), Gaps = 25/236 (10%)
Query: 36 EEVLLEKKG---CTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGK 92
E ++ EK+G G+I LNRPK LNAL +I ++ LK +E+DP I++ G G K
Sbjct: 34 EYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDK 92
Query: 93 AFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152
AF AG DI+ + + + F + L +KP +A ++G GGG L++
Sbjct: 93 AFAAGADIKEMQNLS-FQDCYSSKFLKHWDHLTQV----KKPVIAAVNGYAFGGGCELAM 147
Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAG 211
A EK FA PE IG P GG L R GK L + LTG R+ +D +AG
Sbjct: 148 MCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207
Query: 212 IATHFVD-----------SEKLAMLEEDLLALKSPSKENIASVLENYHTE-SKIDR 255
+ + +EK+A + ++A+ +KE++ + E TE SK+++
Sbjct: 208 LVSKICPVETLVEEAIQCAEKIASNSKIVVAM---AKESVNAAFEMTLTEGSKLEK 260
>gi|4502327 AU RNA binding protein/enoyl-Coenzyme A hydratase
precursor [Homo sapiens]
Length = 339
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/175 (25%), Positives = 85/175 (48%), Gaps = 4/175 (2%)
Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107
V+ +NR N+L+ N+I+ + + + D + III+ FCAG D++ A+
Sbjct: 91 VLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLK--ERAK 148
Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167
+ ++ P + ++N+ + + P +A I G+ +GGG+ L++ RVA +
Sbjct: 149 MSSSEVGPFVSKIRAVIND-IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGL 207
Query: 168 PETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEK 221
ET + + P GG LPR G L L + L G++ G+ +H ++ +
Sbjct: 208 VETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQ 262
>gi|68989263 enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A
dehydrogenase [Homo sapiens]
Length = 723
Score = 69.7 bits (169), Expect = 3e-12
Identities = 56/174 (32%), Positives = 82/174 (47%), Gaps = 11/174 (6%)
Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107
+I L P +NA++ ++R I L+K D I+I GA GK F AG DIR S
Sbjct: 13 LIRLRNPP-VNAISTTLLRDIKEGLQKAVIDHTIKAIVICGAEGK-FSAGADIRGFSAPR 70
Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167
+ V +E N +KP VA I G+ GGG+ L++ +R+A + +
Sbjct: 71 TFGLTLGHVV--DEIQRN------EKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGL 122
Query: 168 PETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSE 220
PE +GL P G LPRL G L +G R+ + + GI V+S+
Sbjct: 123 PEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSD 176
>gi|70995211 peroxisomal enoyl-coenzyme A hydratase-like protein
[Homo sapiens]
Length = 328
Score = 67.4 bits (163), Expect = 2e-11
Identities = 62/260 (23%), Positives = 110/260 (42%), Gaps = 19/260 (7%)
Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS---- 104
+ LNRP NA+ R++ K +D + ++I GAG K F AG D+ ++
Sbjct: 70 VQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAG-KMFTAGIDLMDMASDIL 128
Query: 105 -----EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVA 159
+ + + + R + N + C KP +A +HG +GGGV L R
Sbjct: 129 QPKGDDVARISWYLRDIITRYQETFN-VIERCPKPVIAAVHGGCIGGGVDLVTACDIRYC 187
Query: 160 TEKCLFAMPETAIGLFPDVGGGYFLPRLQG--KLGYFLALTGFRLKGRDVYRAGIATHFV 217
+ F + E +GL DVG LP++ G L LA T ++ + +G+ + V
Sbjct: 188 AQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSR-V 246
Query: 218 DSEKLAMLEEDL-----LALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCF 272
+K ML+ L ++ KSP V Y + + +++ +M + +
Sbjct: 247 FPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQD 306
Query: 273 SANTVEEIIENLQQDGSSFA 292
+V+ EN + +F+
Sbjct: 307 LVKSVQATTENKELKTVTFS 326
>gi|20127408 mitochondrial trifunctional protein, alpha subunit
precursor [Homo sapiens]
Length = 763
Score = 63.9 bits (154), Expect = 2e-10
Identities = 55/218 (25%), Positives = 100/218 (45%), Gaps = 11/218 (5%)
Query: 9 LMSRFNAFKRTNT---ILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKF-LNALTLNM 64
++SRF+AF+ + I + S + KG V+ +N P +N L+ +
Sbjct: 9 ILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKEL 68
Query: 65 IRQIYPQLKK-WEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM 123
+ + + W D ++I G F AG DI +++ A K Q++ + +E
Sbjct: 69 HSEFSEVMNEIWASDQIRSAVLISSKPG-CFIAGADINMLA-ACKTLQEVTQLS-QEAQR 125
Query: 124 LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE--KCLFAMPETAIGLFPDVGGG 181
+ + KP VA I+G +GGG+ +++ Q+R+AT+ K + PE +G P GG
Sbjct: 126 IVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGT 185
Query: 182 YFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVD 218
LP++ G + LTG ++ + G+ V+
Sbjct: 186 QRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVE 223
>gi|31542718 enoyl Coenzyme A hydratase domain containing 3 [Homo
sapiens]
Length = 303
Score = 55.1 bits (131), Expect = 9e-08
Identities = 42/174 (24%), Positives = 79/174 (45%), Gaps = 3/174 (1%)
Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108
I L+ PK N L+L M++ + + + D +II A G F +G D++ ++E E+
Sbjct: 59 IVLSNPKKRNTLSLAMLKSLQSDILH-DADSNDLKVIIISAEGPVFSSGHDLKELTE-EQ 116
Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168
+ A VF ++ + + + P +A+++G+ G L VA++K FA P
Sbjct: 117 GRDYHAEVFQTCSKVMMH-IRNHPVPVIAMVNGLATAAGCQLVASCDIAVASDKSSFATP 175
Query: 169 ETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
+GLF G + K+ + TG + ++ G+ + V +L
Sbjct: 176 GVNVGLFCSTPGVALARAVPRKVALEMLFTGEPISAQEALLHGLLSKVVPEAEL 229
>gi|157694516 enoyl Coenzyme A hydratase domain containing 1 isoform
1 [Homo sapiens]
Length = 301
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 9/185 (4%)
Query: 47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEA 106
G++TLN P +NA + M+ Q+ ++ + E E +I++GA F +G D+ +
Sbjct: 59 GILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSL 117
Query: 107 EKAKQKIAPVFFREEYMLNNAVGSCQKPY--VALIHGITMGGGVGLSVHGQFRVATEKCL 164
+ +A F M N + P VAL+ G +GGG + FR+ T +
Sbjct: 118 GTPEDGMAVCMF----MQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESK 173
Query: 165 FAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTG-FRLKGRDVYRAGIATHFV-DSEKL 222
+G+ P GG L + G L+G +L ++ G+ + S++
Sbjct: 174 IRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDET 233
Query: 223 AMLEE 227
LEE
Sbjct: 234 KSLEE 238
>gi|213417737 enoyl Coenzyme A hydratase domain containing 1 isoform
5 [Homo sapiens]
Length = 307
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 9/185 (4%)
Query: 47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEA 106
G++TLN P +NA + M+ Q+ ++ + E E +I++GA F +G D+ +
Sbjct: 65 GILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSL 123
Query: 107 EKAKQKIAPVFFREEYMLNNAVGSCQKPY--VALIHGITMGGGVGLSVHGQFRVATEKCL 164
+ +A F M N + P VAL+ G +GGG + FR+ T +
Sbjct: 124 GTPEDGMAVCMF----MQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESK 179
Query: 165 FAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTG-FRLKGRDVYRAGIATHFV-DSEKL 222
+G+ P GG L + G L+G +L ++ G+ + S++
Sbjct: 180 IRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDET 239
Query: 223 AMLEE 227
LEE
Sbjct: 240 KSLEE 244
>gi|4757966 Y chromosome chromodomain protein 1, telomeric isoform b
[Homo sapiens]
Length = 554
Score = 48.5 bits (114), Expect = 8e-06
Identities = 42/192 (21%), Positives = 78/192 (40%), Gaps = 5/192 (2%)
Query: 26 LRMSKHTDAAEEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
+R+++ +++++K+ G T ++ R NAL +I++I L D +
Sbjct: 274 IRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSK--L 331
Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM-LNNAVGSCQKPYVALIHGIT 143
++ A G FC G D + + + A + + N +KP V ++G
Sbjct: 332 VLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPA 391
Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRL 202
+G G + A EK F P T G PD P++ GK + + G +L
Sbjct: 392 IGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKL 451
Query: 203 KGRDVYRAGIAT 214
R+ G+ +
Sbjct: 452 TAREACAKGLVS 463
>gi|25453481 Y chromosome chromodomain protein 1, telomeric isoform
a [Homo sapiens]
Length = 540
Score = 48.5 bits (114), Expect = 8e-06
Identities = 42/192 (21%), Positives = 78/192 (40%), Gaps = 5/192 (2%)
Query: 26 LRMSKHTDAAEEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
+R+++ +++++K+ G T ++ R NAL +I++I L D +
Sbjct: 274 IRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSK--L 331
Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM-LNNAVGSCQKPYVALIHGIT 143
++ A G FC G D + + + A + + N +KP V ++G
Sbjct: 332 VLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPA 391
Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRL 202
+G G + A EK F P T G PD P++ GK + + G +L
Sbjct: 392 IGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKL 451
Query: 203 KGRDVYRAGIAT 214
R+ G+ +
Sbjct: 452 TAREACAKGLVS 463
>gi|51538581 chromodomain protein, Y-linked, 1B isoform b [Homo
sapiens]
Length = 554
Score = 48.5 bits (114), Expect = 8e-06
Identities = 42/192 (21%), Positives = 78/192 (40%), Gaps = 5/192 (2%)
Query: 26 LRMSKHTDAAEEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
+R+++ +++++K+ G T ++ R NAL +I++I L D +
Sbjct: 274 IRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSK--L 331
Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM-LNNAVGSCQKPYVALIHGIT 143
++ A G FC G D + + + A + + N +KP V ++G
Sbjct: 332 VLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPA 391
Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRL 202
+G G + A EK F P T G PD P++ GK + + G +L
Sbjct: 392 IGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKL 451
Query: 203 KGRDVYRAGIAT 214
R+ G+ +
Sbjct: 452 TAREACAKGLVS 463
>gi|51538573 chromodomain protein, Y-linked, 1B isoform a [Homo
sapiens]
Length = 540
Score = 48.5 bits (114), Expect = 8e-06
Identities = 42/192 (21%), Positives = 78/192 (40%), Gaps = 5/192 (2%)
Query: 26 LRMSKHTDAAEEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
+R+++ +++++K+ G T ++ R NAL +I++I L D +
Sbjct: 274 IRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSK--L 331
Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM-LNNAVGSCQKPYVALIHGIT 143
++ A G FC G D + + + A + + N +KP V ++G
Sbjct: 332 VLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPA 391
Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRL 202
+G G + A EK F P T G PD P++ GK + + G +L
Sbjct: 392 IGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKL 451
Query: 203 KGRDVYRAGIAT 214
R+ G+ +
Sbjct: 452 TAREACAKGLVS 463
>gi|150378541 enoyl Coenzyme A hydratase domain containing 2 [Homo
sapiens]
Length = 261
Score = 47.4 bits (111), Expect = 2e-05
Identities = 42/170 (24%), Positives = 64/170 (37%), Gaps = 35/170 (20%)
Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108
I +NRP NAL + ++ L + +D + +++ + FCAG D++ E E+
Sbjct: 45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK---EREQ 101
Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168
+ VF + L N + S + +
Sbjct: 102 MSEAEVGVFVQRLRGLMNDIAS-------------------------------SAVMGLI 130
Query: 169 ETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFV 217
ET GL P GG LPR G L L TG RL G + + G+ H V
Sbjct: 131 ETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAV 180
>gi|49355787 Y chromosome chromodomain protein 2B [Homo sapiens]
Length = 541
Score = 45.4 bits (106), Expect = 7e-05
Identities = 41/192 (21%), Positives = 77/192 (40%), Gaps = 5/192 (2%)
Query: 26 LRMSKHTDAAEEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
+R+++ +++++K+ G T ++ R NAL +I+++ L D +
Sbjct: 275 IRLTESAITYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAADDSK--L 332
Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM-LNNAVGSCQKPYVALIHGIT 143
++ A G FC G D + + A + + N +KP V ++G
Sbjct: 333 VLFSAAGSVFCCGLDFGYFVRHLRNDRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPA 392
Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRL 202
+G G + A EK F P T G PD P++ GK + + G +L
Sbjct: 393 IGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKL 452
Query: 203 KGRDVYRAGIAT 214
R+ G+ +
Sbjct: 453 TAREACAKGLVS 464
>gi|4757968 Y chromosome chromodomain protein 2A [Homo sapiens]
Length = 541
Score = 45.4 bits (106), Expect = 7e-05
Identities = 41/192 (21%), Positives = 77/192 (40%), Gaps = 5/192 (2%)
Query: 26 LRMSKHTDAAEEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
+R+++ +++++K+ G T ++ R NAL +I+++ L D +
Sbjct: 275 IRLTESAITYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAADDSK--L 332
Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM-LNNAVGSCQKPYVALIHGIT 143
++ A G FC G D + + A + + N +KP V ++G
Sbjct: 333 VLFSAAGSVFCCGLDFGYFVRHLRNDRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPA 392
Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRL 202
+G G + A EK F P T G PD P++ GK + + G +L
Sbjct: 393 IGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKL 452
Query: 203 KGRDVYRAGIAT 214
R+ G+ +
Sbjct: 453 TAREACAKGLVS 464
>gi|45643119 peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 [Homo
sapiens]
Length = 364
Score = 41.2 bits (95), Expect = 0.001
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 22/201 (10%)
Query: 30 KHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGA 89
K T V+ + G T ++ NRPK NA+ M +I LK +D +I +
Sbjct: 105 KSTGFETLVVTSEDGITKIM-FNRPKKKNAINTEMYHEIMRALKAASKDDS--IITVLTG 161
Query: 90 GGKAFCAGGDIRVISE------AEKAKQKIAPVFFREEYMLNNAVG---SCQKPYVALIH 140
G + +G D+ ++ EKAK +L VG KP +A+++
Sbjct: 162 NGDYYSSGNDLTNFTDIPPGGVEEKAKNNAV--------LLREFVGCFIDFPKPLIAVVN 213
Query: 141 GITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTG 199
G +G V L A+++ F P + +G P+ Y P++ + + G
Sbjct: 214 GPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKATEMLIFG 273
Query: 200 FRLKGRDVYRAGIATH-FVDS 219
+L + G+ T F DS
Sbjct: 274 KKLTAGEACAQGLVTEVFPDS 294
>gi|221307494 chromodomain protein, Y chromosome-like isoform a
[Homo sapiens]
Length = 544
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 12/183 (6%)
Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAG 97
V+ ++ G T ++ + N+L ++R++ L D +++ A G FC G
Sbjct: 291 VVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLL--SAVGSVFCCG 348
Query: 98 GDI-----RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152
D R+ + ++ K+A N +KP + ++G +G G +
Sbjct: 349 LDFIYFIRRLTDDRKRESTKMAEAIRN----FVNTFIQFKKPIIVAVNGPAIGLGASILP 404
Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ-GKLGYFLALTGFRLKGRDVYRAG 211
A EK F P T G PD P++ G + L+G +L ++ G
Sbjct: 405 LCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKG 464
Query: 212 IAT 214
+ +
Sbjct: 465 LVS 467
>gi|221136756 chromodomain protein, Y chromosome-like isoform d
[Homo sapiens]
Length = 412
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 12/183 (6%)
Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAG 97
V+ ++ G T ++ + N+L ++R++ L D +++ A G FC G
Sbjct: 159 VVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLL--SAVGSVFCCG 216
Query: 98 GDI-----RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152
D R+ + ++ K+A N +KP + ++G +G G +
Sbjct: 217 LDFIYFIRRLTDDRKRESTKMAEAIRN----FVNTFIQFKKPIIVAVNGPAIGLGASILP 272
Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ-GKLGYFLALTGFRLKGRDVYRAG 211
A EK F P T G PD P++ G + L+G +L ++ G
Sbjct: 273 LCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKG 332
Query: 212 IAT 214
+ +
Sbjct: 333 LVS 335
>gi|221136753 chromodomain protein, Y chromosome-like isoform d
[Homo sapiens]
Length = 412
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 12/183 (6%)
Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAG 97
V+ ++ G T ++ + N+L ++R++ L D +++ A G FC G
Sbjct: 159 VVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLL--SAVGSVFCCG 216
Query: 98 GDI-----RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152
D R+ + ++ K+A N +KP + ++G +G G +
Sbjct: 217 LDFIYFIRRLTDDRKRESTKMAEAIRN----FVNTFIQFKKPIIVAVNGPAIGLGASILP 272
Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ-GKLGYFLALTGFRLKGRDVYRAG 211
A EK F P T G PD P++ G + L+G +L ++ G
Sbjct: 273 LCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKG 332
Query: 212 IAT 214
+ +
Sbjct: 333 LVS 335
>gi|157694520 enoyl Coenzyme A hydratase domain containing 1 isoform
3 [Homo sapiens]
Length = 226
Score = 38.9 bits (89), Expect = 0.007
Identities = 39/168 (23%), Positives = 69/168 (41%), Gaps = 9/168 (5%)
Query: 64 MIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM 123
M+ Q+ ++ + E E +I++GA F +G D+ + + +A F M
Sbjct: 1 MMLQLLEKVIELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSLGTPEDGMAVCMF----M 55
Query: 124 LNNAVGSCQKPY--VALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGG 181
N + P VAL+ G +GGG + FR+ T + +G+ P GG
Sbjct: 56 QNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGT 115
Query: 182 YFLPRLQGKLGYFLALTG-FRLKGRDVYRAGIATHFV-DSEKLAMLEE 227
L + G L+G +L ++ G+ + S++ LEE
Sbjct: 116 TRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEE 163
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 36.2 bits (82), Expect = 0.043
Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 8/139 (5%)
Query: 201 RLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFI 260
+LKG++V I + + + +LL + + EN + K +RDKS
Sbjct: 792 QLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIE 851
Query: 261 LEEH-MDKINSCFSA--NTVEEIIENLQQDGSSFALEQLKVIN--KMSPTSLKITLRQLM 315
L+++ M+K++S A V+ I+E Q + + A E+ K I+ + ++ +R+L+
Sbjct: 852 LQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIEKEMRELL 911
Query: 316 EGSSKTLQEVLTMEYRLSQ 334
E +T + TME ++ Q
Sbjct: 912 E---ETCKNKKTMEAKIKQ 927
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 36.2 bits (82), Expect = 0.043
Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 8/139 (5%)
Query: 201 RLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFI 260
+LKG++V I + + + +LL + + EN + K +RDKS
Sbjct: 885 QLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIE 944
Query: 261 LEEH-MDKINSCFSA--NTVEEIIENLQQDGSSFALEQLKVIN--KMSPTSLKITLRQLM 315
L+++ M+K++S A V+ I+E Q + + A E+ K I+ + ++ +R+L+
Sbjct: 945 LQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIEKEMRELL 1004
Query: 316 EGSSKTLQEVLTMEYRLSQ 334
E +T + TME ++ Q
Sbjct: 1005 E---ETCKNKKTMEAKIKQ 1020
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 35.8 bits (81), Expect = 0.056
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
Query: 217 VDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANT 276
V E+LA LE D K ++ + + + + RD F LEEH +K+N+
Sbjct: 101 VYQERLARLEND----KESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNA------ 150
Query: 277 VEEIIENLQQDGSSFALEQLKVINKMSPTSLKIT 310
EE+++ +S ++L ++ ++S LK+T
Sbjct: 151 TEEMLQQELLSRTSLETQKLDLMAEISNLKLKLT 184
>gi|111955063 GTP-binding protein 10 isoform 1 [Homo sapiens]
Length = 308
Score = 32.0 bits (71), Expect = 0.81
Identities = 40/195 (20%), Positives = 89/195 (45%), Gaps = 29/195 (14%)
Query: 88 GAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLN------------NAVGSC---Q 132
G GGK GGD+ V+++ +++ + R+ ++ +++ SC
Sbjct: 37 GEGGK----GGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKFPNAGKSSLLSCVSHA 92
Query: 133 KPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGY-FLPRLQG-- 189
KP +A T+ +G ++ F+ + + +P G + G G+ FL ++
Sbjct: 93 KPAIADYAFTTLKPELGKIMYSDFKQIS---VADLPGLIEGAHMNKGMGHKFLKHIERTR 149
Query: 190 KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLL---ALKSPSKENIASVLEN 246
+L + + ++GF+L YR T + +++L + +E+L AL + +K ++ +
Sbjct: 150 QLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDK 209
Query: 247 YH-TESKIDRDKSFI 260
+H S++ K F+
Sbjct: 210 FHELMSQLQNPKDFL 224
>gi|50593027 enoyl Coenzyme A hydratase domain containing 1 isoform
2 [Homo sapiens]
Length = 145
Score = 31.2 bits (69), Expect = 1.4
Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVI 103
G++TLN P +NA + M+ Q+ ++ + E E +I++GA F +G D+ +
Sbjct: 59 GILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAV 114
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 30.8 bits (68), Expect = 1.8
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
Query: 218 DSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTV 277
D EK+ LE++ + ++ ++ +L + +D +F+LEE DK+N +
Sbjct: 246 DYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKL 305
Query: 278 EEIIENLQQD-----GSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTL 322
+ ENL+Q + LE +KV + S ++ K L + ++ ++KT+
Sbjct: 306 QS--ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQK-ALEEDLQIATKTI 352
>gi|19923599 calmin [Homo sapiens]
Length = 1002
Score = 30.0 bits (66), Expect = 3.1
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 233 KSPSKENIASVLENYHTESKIDRDKSFILEEHMDKI-NSCFSANTVEEIIENLQQDGSSF 291
+SP+ ENIA+ LE T+ I K +H+D + +S F A + ++L++D S +
Sbjct: 840 ESPNLENIANPLEENVTKESISSKKK-EKRKHVDHVESSLFVAPGSVQSSDDLEEDSSDY 898
Query: 292 ALEQLKVINKMSPTSLKITLRQLMEGSSKT 321
++ ++ S + I LR+ SS++
Sbjct: 899 SIP-----SRTSHSDSSIYLRRHTHRSSES 923
>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
sapiens]
Length = 528
Score = 29.6 bits (65), Expect = 4.0
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 251 SKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKIT 310
S I ++++ E + ++NS S + VEE ENL + SF V+ P S +
Sbjct: 73 SSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLR 132
Query: 311 LRQLMEGS 318
L ++ S
Sbjct: 133 LADVLWNS 140
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,645,359
Number of Sequences: 37866
Number of extensions: 480717
Number of successful extensions: 1186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1159
Number of HSP's gapped (non-prelim): 43
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.