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Search of human proteins with 36287069
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo
sapiens]
(546 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo sapiens] 1121 0.0
gi|36287049 K(lysine) acetyltransferase 5 isoform 2 [Homo sapiens] 1047 0.0
gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens] 901 0.0
gi|226371636 MYST histone acetyltransferase 1 isoform 1 [Homo sa... 322 4e-88
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens] 320 2e-87
gi|226371638 MYST histone acetyltransferase 1 isoform 2 [Homo sa... 316 3e-86
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 303 2e-82
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 303 2e-82
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 303 2e-82
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 281 8e-76
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 39 0.009
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 39 0.009
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 39 0.009
gi|150170670 piccolo isoform 2 [Homo sapiens] 39 0.016
gi|150378539 piccolo isoform 1 [Homo sapiens] 39 0.016
gi|95147559 ankyrin repeat domain 43 [Homo sapiens] 38 0.027
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 37 0.061
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 37 0.061
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 37 0.061
gi|163965366 nascent polypeptide-associated complex alpha subuni... 36 0.10
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 35 0.18
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 35 0.18
gi|110832843 TBP-associated factor 4 [Homo sapiens] 35 0.23
gi|55741677 SET domain containing 1A [Homo sapiens] 34 0.39
gi|61743975 SORCS receptor 1 isoform b [Homo sapiens] 34 0.39
gi|61743973 SORCS receptor 1 isoform a [Homo sapiens] 34 0.39
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 33 0.51
gi|42475941 zinc finger protein 261 [Homo sapiens] 33 0.51
gi|4827067 zinc finger protein 261 [Homo sapiens] 33 0.51
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 33 0.51
>gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo sapiens]
Length = 546
Score = 1121 bits (2899), Expect = 0.0
Identities = 546/546 (100%), Positives = 546/546 (100%)
Query: 1 MAEVVSPVPGAGRREPGEVGRARGPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWP 60
MAEVVSPVPGAGRREPGEVGRARGPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWP
Sbjct: 1 MAEVVSPVPGAGRREPGEVGRARGPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWP 60
Query: 61 LAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSR 120
LAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSR
Sbjct: 61 LAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSR 120
Query: 121 PGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRST 180
PGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRST
Sbjct: 121 PGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRST 180
Query: 181 KRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIP 240
KRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIP
Sbjct: 181 KRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIP 240
Query: 241 SAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCL 300
SAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCL
Sbjct: 241 SAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCL 300
Query: 301 KYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHK 360
KYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHK
Sbjct: 301 KYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHK 360
Query: 361 TLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIE 420
TLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIE
Sbjct: 361 TLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIE 420
Query: 421 FSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEI 480
FSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEI
Sbjct: 421 FSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEI 480
Query: 481 TSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDW 540
TSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDW
Sbjct: 481 TSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDW 540
Query: 541 SKRGKW 546
SKRGKW
Sbjct: 541 SKRGKW 546
>gi|36287049 K(lysine) acetyltransferase 5 isoform 2 [Homo sapiens]
Length = 513
Score = 1047 bits (2707), Expect = 0.0
Identities = 509/509 (100%), Positives = 509/509 (100%)
Query: 38 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLD 97
GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLD
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLD 64
Query: 98 LKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREA 157
LKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREA
Sbjct: 65 LKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREA 124
Query: 158 IPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQP 217
IPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQP
Sbjct: 125 IPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQP 184
Query: 218 GRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKP 277
GRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKP
Sbjct: 185 GRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKP 244
Query: 278 WYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEI 337
WYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEI
Sbjct: 245 WYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEI 304
Query: 338 DGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTED 397
DGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTED
Sbjct: 305 DGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTED 364
Query: 398 YNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILE 457
YNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILE
Sbjct: 365 YNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILE 424
Query: 458 ILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGH 517
ILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGH
Sbjct: 425 ILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGH 484
Query: 518 ERAMLKRLLRIDSKCLHFTPKDWSKRGKW 546
ERAMLKRLLRIDSKCLHFTPKDWSKRGKW
Sbjct: 485 ERAMLKRLLRIDSKCLHFTPKDWSKRGKW 513
>gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens]
Length = 461
Score = 901 bits (2329), Expect = 0.0
Identities = 450/509 (88%), Positives = 450/509 (88%), Gaps = 52/509 (10%)
Query: 38 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLD 97
GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLD
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLD 64
Query: 98 LKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREA 157
LKKIQFPKKEAKTPTKNGLP
Sbjct: 65 LKKIQFPKKEAKTPTKNGLP---------------------------------------- 84
Query: 158 IPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQP 217
G P P R KRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQP
Sbjct: 85 --GSRPGSP----------EREVKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQP 132
Query: 218 GRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKP 277
GRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKP
Sbjct: 133 GRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKP 192
Query: 278 WYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEI 337
WYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEI
Sbjct: 193 WYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEI 252
Query: 338 DGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTED 397
DGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTED
Sbjct: 253 DGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTED 312
Query: 398 YNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILE 457
YNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILE
Sbjct: 313 YNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILE 372
Query: 458 ILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGH 517
ILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGH
Sbjct: 373 ILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGH 432
Query: 518 ERAMLKRLLRIDSKCLHFTPKDWSKRGKW 546
ERAMLKRLLRIDSKCLHFTPKDWSKRGKW
Sbjct: 433 ERAMLKRLLRIDSKCLHFTPKDWSKRGKW 461
>gi|226371636 MYST histone acetyltransferase 1 isoform 1 [Homo
sapiens]
Length = 458
Score = 322 bits (826), Expect = 4e-88
Identities = 162/327 (49%), Positives = 221/327 (67%), Gaps = 11/327 (3%)
Query: 213 VAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGR 272
+A QP RK N ++ T +L ++ H+ I T++K ++ I +G
Sbjct: 130 LAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAAL--EKEHEAI-TKVKYVDKIHIGN 186
Query: 273 HRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTI 332
+ + WYFSP+P++ P L+LCE+CLKY + K + HL +C R PPG EIYRK I
Sbjct: 187 YEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNI 246
Query: 333 SFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEK 392
S +E+DG+ +K Y QNLCLLAK FLDHKTLY+D +PF+FY++TE D +G HIVGYFSKEK
Sbjct: 247 SVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEK 306
Query: 393 ESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWS 452
ES + NVACILTLPPYQRRGYGK LI FSYELSK+E G+PEKPLSDLG LSYRSYWS
Sbjct: 307 ESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWS 366
Query: 453 QTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSED 512
+LEIL R ++I ++S++TSI + D+ISTLQ LN++ Y+KGQ+++ ++
Sbjct: 367 WVLLEILRDF------RGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK 420
Query: 513 IVDGHERA--MLKRLLRIDSKCLHFTP 537
+V+ H ++ K + +DS CL + P
Sbjct: 421 LVEEHLKSAQYKKPPITVDSVCLKWAP 447
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/106 (37%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 1 MAEVVSPVPGAGRREPGEVGRARG----PPVADPGVALSPQGEIIEGCRLPVLRRNQDNE 56
+A S V G G PGE A G P P + E+ L R D+
Sbjct: 10 VAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDST 69
Query: 57 DEWPLAEILS--VKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKK 100
W AE++ V D GR+ FYVHY+ FN+RLDEWV RL L K
Sbjct: 70 --WHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTK 113
>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
Length = 611
Score = 320 bits (821), Expect = 2e-87
Identities = 157/297 (52%), Positives = 205/297 (69%), Gaps = 8/297 (2%)
Query: 244 RMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYG 303
R + L R I I+ I GR+ L WY SPYP+E L LY+CEFCLKY
Sbjct: 316 RASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYM 375
Query: 304 RSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLY 363
+S L+RH+ KC +HPPG+EIYRKG+IS FE+DG+KNK Y QNLCLLAK FLDHKTLY
Sbjct: 376 KSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLY 435
Query: 364 YDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSY 423
YD +PFLFYVMTE D G H++GYFSKEK S +YNV+CILT+P Y R+GYGK+LI+FSY
Sbjct: 436 YDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSY 495
Query: 424 ELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSI 483
LSKVE K G+PE+PLSDLGL+SYRSYW + +L L + + +I+I EIS+ T++
Sbjct: 496 LLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGK-----EISIKEISQETAV 550
Query: 484 KKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRL---LRIDSKCLHFTP 537
D++STLQ L ++ Y+KG++++ +D++D KR +D CL +TP
Sbjct: 551 NPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTP 607
>gi|226371638 MYST histone acetyltransferase 1 isoform 2 [Homo
sapiens]
Length = 467
Score = 316 bits (810), Expect = 3e-86
Identities = 156/305 (51%), Positives = 210/305 (68%), Gaps = 9/305 (2%)
Query: 213 VAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGR 272
+A QP RK N ++ T +L ++ H+ I T++K ++ I +G
Sbjct: 130 LAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAAL--EKEHEAI-TKVKYVDKIHIGN 186
Query: 273 HRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTI 332
+ + WYFSP+P++ P L+LCE+CLKY + K + HL +C R PPG EIYRK I
Sbjct: 187 YEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNI 246
Query: 333 SFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEK 392
S +E+DG+ +K Y QNLCLLAK FLDHKTLY+D +PF+FY++TE D +G HIVGYFSKEK
Sbjct: 247 SVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEK 306
Query: 393 ESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWS 452
ES + NVACILTLPPYQRRGYGK LI FSYELSK+E G+PEKPLSDLG LSYRSYWS
Sbjct: 307 ESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWS 366
Query: 453 QTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSED 512
+LEIL R ++I ++S++TSI + D+ISTLQ LN++ Y+KGQ+++ ++
Sbjct: 367 WVLLEILRDF------RGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK 420
Query: 513 IVDGH 517
+V+ H
Sbjct: 421 LVEEH 425
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/106 (37%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 1 MAEVVSPVPGAGRREPGEVGRARG----PPVADPGVALSPQGEIIEGCRLPVLRRNQDNE 56
+A S V G G PGE A G P P + E+ L R D+
Sbjct: 10 VAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDST 69
Query: 57 DEWPLAEILS--VKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKK 100
W AE++ V D GR+ FYVHY+ FN+RLDEWV RL L K
Sbjct: 70 --WHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTK 113
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 303 bits (777), Expect = 2e-82
Identities = 147/273 (53%), Positives = 191/273 (69%), Gaps = 9/273 (3%)
Query: 268 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 327
IE G++ + WY SPYPQE + LP LYLCEFCLKY +S LQ+H+ KC HPP NEIY
Sbjct: 512 IEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIY 571
Query: 328 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 387
RK IS FE+DG + Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 572 RKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGY 631
Query: 388 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 447
FSKEK + YNV+CI+ LP YQR+GYG+ LI+FSY LSK EG+ G+PEKPLSDLG LSY
Sbjct: 632 FSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSY 691
Query: 448 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 507
+YW ILE L + QI+I ++S++T I +D+ STL +L ++++ Q+++
Sbjct: 692 MAYWKSVILECLYHQNDK-----QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI 746
Query: 508 TLSEDIVDGHERAMLKRLLR---IDSKCLHFTP 537
E ++ H A L+ LR +D +CL +TP
Sbjct: 747 IRREKLIQDH-MAKLQLNLRPVDVDPECLRWTP 778
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 303 bits (777), Expect = 2e-82
Identities = 147/273 (53%), Positives = 191/273 (69%), Gaps = 9/273 (3%)
Query: 268 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 327
IE G++ + WY SPYPQE + LP LYLCEFCLKY +S LQ+H+ KC HPP NEIY
Sbjct: 512 IEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIY 571
Query: 328 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 387
RK IS FE+DG + Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 572 RKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGY 631
Query: 388 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 447
FSKEK + YNV+CI+ LP YQR+GYG+ LI+FSY LSK EG+ G+PEKPLSDLG LSY
Sbjct: 632 FSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSY 691
Query: 448 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 507
+YW ILE L + QI+I ++S++T I +D+ STL +L ++++ Q+++
Sbjct: 692 MAYWKSVILECLYHQNDK-----QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI 746
Query: 508 TLSEDIVDGHERAMLKRLLR---IDSKCLHFTP 537
E ++ H A L+ LR +D +CL +TP
Sbjct: 747 IRREKLIQDH-MAKLQLNLRPVDVDPECLRWTP 778
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 303 bits (777), Expect = 2e-82
Identities = 147/273 (53%), Positives = 191/273 (69%), Gaps = 9/273 (3%)
Query: 268 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 327
IE G++ + WY SPYPQE + LP LYLCEFCLKY +S LQ+H+ KC HPP NEIY
Sbjct: 512 IEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIY 571
Query: 328 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 387
RK IS FE+DG + Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 572 RKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGY 631
Query: 388 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 447
FSKEK + YNV+CI+ LP YQR+GYG+ LI+FSY LSK EG+ G+PEKPLSDLG LSY
Sbjct: 632 FSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSY 691
Query: 448 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 507
+YW ILE L + QI+I ++S++T I +D+ STL +L ++++ Q+++
Sbjct: 692 MAYWKSVILECLYHQNDK-----QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI 746
Query: 508 TLSEDIVDGHERAMLKRLLR---IDSKCLHFTP 537
E ++ H A L+ LR +D +CL +TP
Sbjct: 747 IRREKLIQDH-MAKLQLNLRPVDVDPECLRWTP 778
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 281 bits (720), Expect = 8e-76
Identities = 140/272 (51%), Positives = 183/272 (67%), Gaps = 7/272 (2%)
Query: 268 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 327
IE G++ ++ WY SPYPQE LP LYLCEFCLKY +S L RH KC HPP NEIY
Sbjct: 723 IEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIY 782
Query: 328 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 387
R+ +S FE+DG +K Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 783 RRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGY 842
Query: 388 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 447
FSKEK + YNV+CI+ +P +QR+G+G+ LI+FSY LS+ EG+ G+PEKPLSDLG LSY
Sbjct: 843 FSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSY 902
Query: 448 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 507
+YW ILE L ER I+I IS T + D+ +TLQ+L++I+ G++++
Sbjct: 903 LAYWKSVILEYLY----HHHER-HISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 957
Query: 508 TLSEDIVDGHERAM--LKRLLRIDSKCLHFTP 537
E ++ H + R +D L +TP
Sbjct: 958 IRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 39.3 bits (90), Expect = 0.009
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 62 AEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERL--DLKKIQFPKKEAKTPTKNGLPGS 119
A I S + G L+ VHY +N R DEWV +R+ L K PKK+ K KN
Sbjct: 594 ASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDK-GGPKKKQKKKAKNKEDSE 652
Query: 120 RPGSPEREVPASAQASGKTLPIPVQITLRFNLP 152
+ + E Q S + P P++ TL N+P
Sbjct: 653 KDEKRDEE----RQKSKRGRP-PLKSTLSSNMP 680
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 39.3 bits (90), Expect = 0.009
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 62 AEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERL--DLKKIQFPKKEAKTPTKNGLPGS 119
A I S + G L+ VHY +N R DEWV +R+ L K PKK+ K KN
Sbjct: 594 ASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDK-GGPKKKQKKKAKNKEDSE 652
Query: 120 RPGSPEREVPASAQASGKTLPIPVQITLRFNLP 152
+ + E Q S + P P++ TL N+P
Sbjct: 653 KDEKRDEE----RQKSKRGRP-PLKSTLSSNMP 680
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 39.3 bits (90), Expect = 0.009
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 62 AEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERL--DLKKIQFPKKEAKTPTKNGLPGS 119
A I S + G L+ VHY +N R DEWV +R+ L K PKK+ K KN
Sbjct: 594 ASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDK-GGPKKKQKKKAKNKEDSE 652
Query: 120 RPGSPEREVPASAQASGKTLPIPVQITLRFNLP 152
+ + E Q S + P P++ TL N+P
Sbjct: 653 KDEKRDEE----RQKSKRGRP-PLKSTLSSNMP 680
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 10/148 (6%)
Query: 101 IQFPKKE---AKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREA 157
+Q P K KTP + PG P SAQ +G T P P Q+ P ++
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPAKPPPQQ-- 483
Query: 158 IPGGEPDQPLSSSSCLQPNHR--STKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAA 215
PG P S P+ + STK + PA P P + Q + + A
Sbjct: 484 -PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542
Query: 216 QPGRKRKSNCLGTDEDSQDSSDGIPSAP 243
QP + S T SQ S G P P
Sbjct: 543 QPSPAKPSAQQSTKPVSQTGS-GKPLQP 569
Score = 35.4 bits (80), Expect = 0.14
Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 15/112 (13%)
Query: 108 AKTPTKN-GLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQP 166
AK PT+ G P P + PA A KT PVQ + PG P Q
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT---PVQ-----------QPGPGKIPAQQ 453
Query: 167 LSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPG 218
TK ++ PA P P + PA PQ + + + QPG
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Score = 32.0 bits (71), Expect = 1.5
Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 25/127 (19%)
Query: 97 DLKKIQFPKKE---AKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK 153
DL K PKK K PT +G P ++ P S A K +P + +
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE--------Q 744
Query: 154 EREAIPGGEPDQP----------LSSSSCLQPNHRSTKRKVEVVSPATPVPSET---APA 200
++ + +P QP SSS+ +P+ S+K + + TP P +T P+
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PLKTDSAKPS 803
Query: 201 SVFPQNG 207
FP G
Sbjct: 804 QSFPPTG 810
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 10/148 (6%)
Query: 101 IQFPKKE---AKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREA 157
+Q P K KTP + PG P SAQ +G T P P Q+ P ++
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPAKPPPQQ-- 483
Query: 158 IPGGEPDQPLSSSSCLQPNHR--STKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAA 215
PG P S P+ + STK + PA P P + Q + + A
Sbjct: 484 -PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542
Query: 216 QPGRKRKSNCLGTDEDSQDSSDGIPSAP 243
QP + S T SQ S G P P
Sbjct: 543 QPSPAKPSAQQSTKPVSQTGS-GKPLQP 569
Score = 35.4 bits (80), Expect = 0.14
Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 15/112 (13%)
Query: 108 AKTPTKN-GLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQP 166
AK PT+ G P P + PA A KT PVQ + PG P Q
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT---PVQ-----------QPGPGKIPAQQ 453
Query: 167 LSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPG 218
TK ++ PA P P + PA PQ + + + QPG
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Score = 32.0 bits (71), Expect = 1.5
Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 25/127 (19%)
Query: 97 DLKKIQFPKKE---AKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK 153
DL K PKK K PT +G P ++ P S A K +P + +
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE--------Q 744
Query: 154 EREAIPGGEPDQP----------LSSSSCLQPNHRSTKRKVEVVSPATPVPSET---APA 200
++ + +P QP SSS+ +P+ S+K + + TP P +T P+
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PLKTDSAKPS 803
Query: 201 SVFPQNG 207
FP G
Sbjct: 804 QSFPPTG 810
>gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
Length = 549
Score = 37.7 bits (86), Expect = 0.027
Identities = 41/134 (30%), Positives = 53/134 (39%), Gaps = 20/134 (14%)
Query: 104 PKKEAKTPTKNGLPGS--RPGSPEREV-PASAQASGKT----LPIPVQITLRFNLPKERE 156
P+ P G PG+ +P P V P SA A G +P PV+ LP E +
Sbjct: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
Query: 157 AIPGG---EPDQPLSSSSCLQP-----NHRSTKRKVEVVSPATPVPSETA-----PASVF 203
PGG EP QP S P ++T+R +P PSE A P
Sbjct: 143 DTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAE 202
Query: 204 PQNGAARRAVAAQP 217
P GAA+ +P
Sbjct: 203 PGPGAAKGPPQQKP 216
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 36.6 bits (83), Expect = 0.061
Identities = 34/133 (25%), Positives = 50/133 (37%), Gaps = 15/133 (11%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEP 163
P+ A PT P + P P P A+ T L + P E A+P
Sbjct: 209 PETTAAPPTP---PATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVP---- 261
Query: 164 DQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKS 223
P S++ L P+ S + + A P PS T PA P + A + A P S
Sbjct: 262 --PTPSATTLDPSSASAPPE---TTAAPPTPSATTPA---PPSSPAPQETTAAPITTPNS 313
Query: 224 NCLGTDEDSQDSS 236
+ D+ ++S
Sbjct: 314 SPTTLAPDTSETS 326
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 36.6 bits (83), Expect = 0.061
Identities = 34/133 (25%), Positives = 50/133 (37%), Gaps = 15/133 (11%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEP 163
P+ A PT P + P P P A+ T L + P E A+P
Sbjct: 209 PETTAAPPTP---PATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVP---- 261
Query: 164 DQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKS 223
P S++ L P+ S + + A P PS T PA P + A + A P S
Sbjct: 262 --PTPSATTLDPSSASAPPE---TTAAPPTPSATTPA---PPSSPAPQETTAAPITTPNS 313
Query: 224 NCLGTDEDSQDSS 236
+ D+ ++S
Sbjct: 314 SPTTLAPDTSETS 326
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 36.6 bits (83), Expect = 0.061
Identities = 34/133 (25%), Positives = 50/133 (37%), Gaps = 15/133 (11%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEP 163
P+ A PT P + P P P A+ T L + P E A+P
Sbjct: 209 PETTAAPPTP---PATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVP---- 261
Query: 164 DQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKS 223
P S++ L P+ S + + A P PS T PA P + A + A P S
Sbjct: 262 --PTPSATTLDPSSASAPPE---TTAAPPTPSATTPA---PPSSPAPQETTAAPITTPNS 313
Query: 224 NCLGTDEDSQDSS 236
+ D+ ++S
Sbjct: 314 SPTTLAPDTSETS 326
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 35.8 bits (81), Expect = 0.10
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 7/148 (4%)
Query: 105 KKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPG--GE 162
KK T G P + + +PA S K P P Q+ + PK+ A P G
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS-PKKAPATPAPMGA 1502
Query: 163 PDQP--LSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRK 220
P P + SS P S++R + ++P + S+ PA++ P+ A+ +K
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRR--DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 221 RKSNCLGTDEDSQDSSDGIPSAPRMTGS 248
+ + + SS S P +T S
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPS 1588
Score = 34.7 bits (78), Expect = 0.23
Identities = 26/102 (25%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Query: 106 KEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLP---IPVQITLRFNLPKEREAIPGGE 162
K++ T + P S G+P G TLP P + PKE A P +
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 163 PDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFP 204
LS +S R+T + + +P + T PA+ P
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP 948
Score = 34.3 bits (77), Expect = 0.30
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 19/115 (16%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEP 163
P A TP+ G P P SP+R + T P + ++ PK+ A P
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS-----PKKAPATP---- 1419
Query: 164 DQPLSSSSCLQPNHRSTKRKVEVVSPA-TPVPSETAPASVFPQNGAARRAVAAQP 217
+ +T K ++ PA TPV + APA+ P+ G A + P
Sbjct: 1420 ---------VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Score = 33.1 bits (74), Expect = 0.67
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 7/109 (6%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQI----TLRFNLPKEREAIP 159
PKK PT P + PA ++ K P P ++ + PKE P
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Query: 160 GGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGA 208
P P + P T V+P++ S T+PASV + GA
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTS---PPVTPSSLKDSPTSPASVTCKMGA 1663
Score = 31.6 bits (70), Expect = 2.0
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 20/157 (12%)
Query: 96 LDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKER 155
L K + P KE TP+ LP + G P P A A +++ + PK+
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEG-PATPAPKQAPA----------LSMTSSSPKKA 921
Query: 156 EAIPG--GEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVP--SETAPASV--FPQNGAA 209
A P G P P + P K PATP P + T PA+ P+ G A
Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSPK---GGPATPSPKWAPTPPAATPPSPKGGPA 978
Query: 210 RRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMT 246
+ P + + S G P+ P +T
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Score = 30.4 bits (67), Expect = 4.3
Identities = 43/168 (25%), Positives = 53/168 (31%), Gaps = 29/168 (17%)
Query: 104 PKKEAKTPTKNGLPGS-----RPGSPEREVPA----SAQASGKTLPIPVQIT-------L 147
PKK TP G+P S P P P+ A S K P P T
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 148 RFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-----ATPVP--SETAPA 200
PK P P P + P T V SP ATP P + T PA
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 201 SVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGS 248
+ P + A G T + S G P+ P + G+
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPT------TPAATLPSPKGGPATPSLKGA 1079
Score = 30.0 bits (66), Expect = 5.7
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
Query: 117 PGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPN 176
PGS PA+ S ++LP+ ++ A P PD P+S S L P
Sbjct: 261 PGSLSLKGPVSPPAALSLSTQSLPVVTS--------SQKTAGPNTPPDFPISLGSHLAPL 312
Query: 177 HRSTKRKVEVVSPATP 192
H+S+ V+++ P
Sbjct: 313 HQSSFGSVQLLGQTGP 328
Score = 29.6 bits (65), Expect = 7.4
Identities = 31/119 (26%), Positives = 40/119 (33%), Gaps = 4/119 (3%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIP--GG 161
PK TP+ G P +P A S K P+P T PK A P G
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP--PSPKGGLATPPHKG 1124
Query: 162 EPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRK 220
P P ++ + + K +PA PS + P GA A P K
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Score = 29.6 bits (65), Expect = 7.4
Identities = 37/113 (32%), Positives = 49/113 (43%), Gaps = 20/113 (17%)
Query: 104 PKKEAKTPTKNG---LPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPG 160
PKK TP G LP P SP +EVPA+ S + PI TL L K+ A
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSP-KEVPAT--PSSRRDPIAPTATL---LSKKTPATLA 1543
Query: 161 GEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAV 213
P + L + P+ + T PA P P E APA+ + ++ AV
Sbjct: 1544 --PKEALIPPAMTVPSPKKT--------PAIPTPKE-APATPSSKEASSPPAV 1585
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 35.0 bits (79), Expect = 0.18
Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 8/136 (5%)
Query: 121 PGSPEREVPASAQASGKTLPI--PVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHR 178
P P++ + + +Q P+ P+ +++ + K R+ P+ PLSS L+P H
Sbjct: 1046 PAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSE--LEPFHP 1103
Query: 179 STKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDG 238
K + S TP P+ +A P A+ + +S T+ S + +
Sbjct: 1104 KPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSR---TNRSSVKTPEP 1160
Query: 239 -IPSAPRMTGSLVSDR 253
+P+AP + S +D+
Sbjct: 1161 VVPTAPELQPSTSTDQ 1176
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 35.0 bits (79), Expect = 0.18
Identities = 42/147 (28%), Positives = 58/147 (39%), Gaps = 15/147 (10%)
Query: 84 NKRLDEWVTH-----ERLDLKKIQ----FPKKEAKTPTKNGLPGSRPGSPEREVPASAQA 134
N+RL E + ERL + +Q FP A P NG G P + + + +
Sbjct: 733 NQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSSDSLS 792
Query: 135 SGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPAT--- 191
+ K+ P + L +L E G P + SSS L + + SPAT
Sbjct: 793 TSKSPPGKSSLGLDNSLSTSSEDPHSGCPSR---SSSSLSFHSTPPPLPLLQQSPATLPL 849
Query: 192 PVPSETAPASVFPQNGAARRAVAAQPG 218
+P AP PQNG R AA G
Sbjct: 850 ALPGAPAPLPPQPQNGLGRAPGAAGLG 876
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 34.7 bits (78), Expect = 0.23
Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 15/132 (11%)
Query: 96 LDLKKIQFPKKEAKTPTKNGLPG----SRPGSPEREVPASAQASGKTLPIPVQITLRFNL 151
L L K P +TP G + P P PA A A+ P P TL
Sbjct: 226 LPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA-APAAAPPPPPPAPATL---- 280
Query: 152 PKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARR 211
A P G P P +++ + P + +PA P P+ PA V Q G
Sbjct: 281 -----ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA-PAPAAGGPAGVSGQPGPGAA 334
Query: 212 AVAAQPGRKRKS 223
A A PG K +S
Sbjct: 335 AAAPAPGVKAES 346
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 33.9 bits (76), Expect = 0.39
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 13/121 (10%)
Query: 104 PKKEAKTPT----KNGLPGSRPGSPEREVP----ASAQASGKTLPIPVQITLRFNLPKER 155
P +E PT + +P GSP +P + A+ +G T P LR P
Sbjct: 1080 PPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAG 1139
Query: 156 EAIPGGEPDQPLSSSSCLQPNHRSTKRKVEV----VSPATPVPSETAPASVFPQNGAARR 211
P PD+ SS L P + ++ V V PA P T P + FP A+R+
Sbjct: 1140 PPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP-GPASRK 1198
Query: 212 A 212
A
Sbjct: 1199 A 1199
>gi|61743975 SORCS receptor 1 isoform b [Homo sapiens]
Length = 1198
Score = 33.9 bits (76), Expect = 0.39
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 14/68 (20%)
Query: 188 SPATPVPSETAPA-SVFPQNGA----------ARRAVAAQPGRKRKSNCLGTDEDSQDSS 236
+PATP+P P SV P + A A AVAA+ GR+R+S G D++ +
Sbjct: 65 APATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRS---GADQEKAERG 121
Query: 237 DGIPSAPR 244
+G +PR
Sbjct: 122 EGASRSPR 129
>gi|61743973 SORCS receptor 1 isoform a [Homo sapiens]
Length = 1168
Score = 33.9 bits (76), Expect = 0.39
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 14/68 (20%)
Query: 188 SPATPVPSETAPA-SVFPQNGA----------ARRAVAAQPGRKRKSNCLGTDEDSQDSS 236
+PATP+P P SV P + A A AVAA+ GR+R+S G D++ +
Sbjct: 65 APATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRS---GADQEKAERG 121
Query: 237 DGIPSAPR 244
+G +PR
Sbjct: 122 EGASRSPR 129
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 33.5 bits (75), Expect = 0.51
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 17/154 (11%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKE----REAIP 159
P TP + P + +PE P S A+ T P P+E A+P
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEE--PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVP 1125
Query: 160 GGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASV---FPQNGAARRAVAAQ 216
P++P S ++ + T + +PA P P E+A A+V P+ A+ A
Sbjct: 1126 --TPEEPASPAAAVP-----TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT 1178
Query: 217 PGRKRK-SNCLGTDEDSQDSSDGIPSAPRMTGSL 249
P + + T E+ + +P+ M +L
Sbjct: 1179 PAESASFAAVVATLEEPTSPAASVPTPAAMVATL 1212
>gi|42475941 zinc finger protein 261 [Homo sapiens]
Length = 1370
Score = 33.5 bits (75), Expect = 0.51
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 6/117 (5%)
Query: 146 TLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQ 205
T R P + E +P G+P P + S P+ T S P S P
Sbjct: 167 TARRGSPGQEEELPQGQPQSPNAPPS---PSVGETLGDGINSSQTKPGGSSPPAHPSLPG 223
Query: 206 NGAARRAVAAQPGRKRKSNCLGTDEDSQ---DSSDGIPSAPRMTGSLVSDRSHDDIV 259
+G +A P RKR + DS++ IP + + ++V D + +D V
Sbjct: 224 DGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFV 280
>gi|4827067 zinc finger protein 261 [Homo sapiens]
Length = 1370
Score = 33.5 bits (75), Expect = 0.51
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 6/117 (5%)
Query: 146 TLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQ 205
T R P + E +P G+P P + S P+ T S P S P
Sbjct: 167 TARRGSPGQEEELPQGQPQSPNAPPS---PSVGETLGDGINSSQTKPGGSSPPAHPSLPG 223
Query: 206 NGAARRAVAAQPGRKRKSNCLGTDEDSQ---DSSDGIPSAPRMTGSLVSDRSHDDIV 259
+G +A P RKR + DS++ IP + + ++V D + +D V
Sbjct: 224 DGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFV 280
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 33.5 bits (75), Expect = 0.51
Identities = 37/183 (20%), Positives = 72/183 (39%), Gaps = 42/183 (22%)
Query: 104 PKKEAKTPTKNGLPGSRPGSPEREVP-----------------------ASAQASGKTLP 140
P KE K P+ G +P S + P +S ++ + P
Sbjct: 1002 PVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPEKSLRKGRPALASQESSLSSTSPSSP 1061
Query: 141 IPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPA 200
+PV+++L+ + + + A SS + QP S+ + + VS +P ++A A
Sbjct: 1062 LPVKVSLKPSRSRSK-ADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSPQKQKSASA 1120
Query: 201 SVFPQNGAARRAVAA-------QPGRKRKSN----------CLGTDEDSQDSSDGIPSAP 243
+ + + + + PG+ R S+ LG+D S S+ P++P
Sbjct: 1121 LTYTASSTSAKKASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTSK-PNSP 1179
Query: 244 RMT 246
R++
Sbjct: 1180 RVS 1182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,928,147
Number of Sequences: 37866
Number of extensions: 1330009
Number of successful extensions: 5132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 141
Number of HSP's that attempted gapping in prelim test: 4881
Number of HSP's gapped (non-prelim): 374
length of query: 546
length of database: 18,247,518
effective HSP length: 107
effective length of query: 439
effective length of database: 14,195,856
effective search space: 6231980784
effective search space used: 6231980784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.