Guide to the Human Genome
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Search of human proteins with 33695153

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33695153 guanine nucleotide binding protein (G protein),
alpha activating activity polypeptide, olfactory type isoform 1 [Homo
sapiens]
         (458 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33695153 guanine nucleotide binding protein (G protein), alph...   929   0.0  
gi|4504043 guanine nucleotide binding protein (G protein), alpha...   705   0.0  
gi|215272301 guanine nucleotide binding protein (G protein), alp...   705   0.0  
gi|117938759 GNAS complex locus XLas [Homo sapiens]                   598   e-171
gi|117938765 GNAS complex locus isoform g [Homo sapiens]              597   e-171
gi|18426900 GNAS complex locus GNASS [Homo sapiens]                   593   e-169
gi|4504047 GNAS complex locus GNASL [Homo sapiens]                    588   e-168
gi|117938762 GNAS complex locus isoform f [Homo sapiens]              588   e-168
gi|40254462 guanine nucleotide binding protein (G protein), q po...   277   1e-74
gi|115511049 guanine nucleotide binding protein (G protein), alp...   272   5e-73
gi|4758444 G alpha 14 [Homo sapiens]                                  266   4e-71
gi|156139155 guanine nucleotide binding protein, alpha transduci...   266   4e-71
gi|20330805 guanine nucleotide binding protein, alpha transducin...   265   8e-71
gi|162461738 guanine nucleotide binding protein, alpha activatin...   264   1e-70
gi|33946324 guanine nucleotide binding protein (G protein), alph...   262   4e-70
gi|10567816 guanine nucleotide binding protein, alpha activating...   262   5e-70
gi|22027522 rod-type transducin alpha subunit [Homo sapiens]          261   7e-70
gi|22027520 rod-type transducin alpha subunit [Homo sapiens]          261   7e-70
gi|5729850 guanine nucleotide binding protein (G protein), alpha...   259   3e-69
gi|4504041 guanine nucleotide binding protein (G protein), alpha...   259   5e-69
gi|156104883 guanine nucleotide binding protein (G protein), alp...   252   4e-67
gi|4504051 guanine nucleotide binding protein, alpha z polypepti...   247   2e-65
gi|42476111 guanine nucleotide binding protein (G protein) alpha...   228   7e-60
gi|24111250 guanine nucleotide binding protein (G protein), alph...   225   7e-59
gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]                    42   9e-04
gi|4502209 ADP-ribosylation factor 5 [Homo sapiens]                    42   0.001
gi|13376574 ADP-ribosylation factor-like 14 [Homo sapiens]             41   0.002
gi|153791535 general control of amino acid synthesis 5-like 2 [H...    39   0.010
gi|59853162 thymine-DNA glycosylase [Homo sapiens]                     38   0.017
gi|197927203 ADP-ribosylation factor related protein 1 isoform b...    38   0.022

>gi|33695153 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           1 [Homo sapiens]
          Length = 458

 Score =  929 bits (2400), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MGLCYSLRPLLFGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGS 60
           MGLCYSLRPLLFGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGS
Sbjct: 1   MGLCYSLRPLLFGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGS 60

Query: 61  PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH 120
           PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH
Sbjct: 61  PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH 120

Query: 121 RLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPP 180
           RLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPP
Sbjct: 121 RLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPP 180

Query: 181 VPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQ 240
           VPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQ
Sbjct: 181 VPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQ 240

Query: 241 YFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQ 300
           YFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQ
Sbjct: 241 YFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQ 300

Query: 301 CFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDM 360
           CFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDM
Sbjct: 301 CFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDM 360

Query: 361 LAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGK 420
           LAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGK
Sbjct: 361 LAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGK 420

Query: 421 HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 458
           HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
Sbjct: 421 HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 458


>gi|4504043 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  705 bits (1819), Expect = 0.0
 Identities = 345/363 (95%), Positives = 354/363 (97%)

Query: 96  KEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 155
           KE R+ ++ I++ L+ ++   + THRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK
Sbjct: 19  KERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 78

Query: 156 ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK 215
           ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK
Sbjct: 79  ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK 138

Query: 216 KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR 275
           KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR
Sbjct: 139 KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR 198

Query: 276 FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD 335
           FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD
Sbjct: 199 FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD 258

Query: 336 LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED 395
           LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED
Sbjct: 259 LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED 318

Query: 396 PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY 455
           PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY
Sbjct: 319 PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY 378

Query: 456 ELL 458
           ELL
Sbjct: 379 ELL 381


>gi|215272301 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  705 bits (1819), Expect = 0.0
 Identities = 345/363 (95%), Positives = 354/363 (97%)

Query: 96  KEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 155
           KE R+ ++ I++ L+ ++   + THRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK
Sbjct: 19  KERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 78

Query: 156 ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK 215
           ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK
Sbjct: 79  ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK 138

Query: 216 KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR 275
           KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR
Sbjct: 139 KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR 198

Query: 276 FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD 335
           FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD
Sbjct: 199 FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD 258

Query: 336 LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED 395
           LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED
Sbjct: 259 LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED 318

Query: 396 PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY 455
           PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY
Sbjct: 319 PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY 378

Query: 456 ELL 458
           ELL
Sbjct: 379 ELL 381


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score =  598 bits (1541), Expect = e-171
 Identities = 295/417 (70%), Positives = 342/417 (82%), Gaps = 17/417 (4%)

Query: 59   GSPACARPKADKP-KEKRQRTEQLSAEEREAAKEREAVKEA-RKVSRGIDRMLRDQKRDL 116
            G     +PKA +  K K+    +   + R+ A E+ A K A +K S+ ID+ L+D+K   
Sbjct: 621  GRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGY 680

Query: 117  QQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE---------------EKKQKILDIRK 161
              THRLLLLGAGESGKSTIVKQMRILHVNGFN E               EK  K+ DI+ 
Sbjct: 681  MCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKN 740

Query: 162  NVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDE 221
            N+K+AI TIV+AMS ++PPV LANPENQFR DYI S+  + DF++  EF++H K LW+DE
Sbjct: 741  NLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDE 800

Query: 222  GVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKV 281
            GV+AC+ERSNEYQLIDCAQYFL++ID +   DY P+DQDLLRCRVLTSGIFET+FQVDKV
Sbjct: 801  GVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKV 860

Query: 282  NFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIW 341
            NFHMFDVGGQRDERRKWIQCFNDVTAII+V A SSYNMVIREDN TNRL+E+L+LF+SIW
Sbjct: 861  NFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIW 920

Query: 342  NNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRA 401
            NNRWLRTIS+ILFLNKQD+LAEKVLAGKSKIEDYFPE+A YT PEDATP+ GEDP+VTRA
Sbjct: 921  NNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRA 980

Query: 402  KFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 458
            K+FIRD FLRISTA+GDG+HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHL+QYELL
Sbjct: 981  KYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 1037


>gi|117938765 GNAS complex locus isoform g [Homo sapiens]
          Length = 379

 Score =  597 bits (1540), Expect = e-171
 Identities = 281/368 (76%), Positives = 326/368 (88%)

Query: 91  EREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE 150
           +R   K  R+ ++ I++ L+  K+  + THRLLLLGAGESGKSTIVKQMRILHVNGFN +
Sbjct: 12  QRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGD 71

Query: 151 EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEF 210
           EK  K+ DI+ N+K+AI TIV+AMS ++PPV LANPENQFR DYI S+  + DF++  EF
Sbjct: 72  EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEF 131

Query: 211 FDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSG 270
           ++H K LW+DEGV+AC+ERSNEYQLIDCAQYFL++ID +   DY P+DQDLLRCRVLTSG
Sbjct: 132 YEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSG 191

Query: 271 IFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRL 330
           IFET+FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAII+V A SSYNMVIREDN TNRL
Sbjct: 192 IFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRL 251

Query: 331 RESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATP 390
           +E+L+LF+SIWNNRWLRTIS+ILFLNKQD+LAEKVLAGKSKIEDYFPE+A YT PEDATP
Sbjct: 252 QEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATP 311

Query: 391 DAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRM 450
           + GEDP+VTRAK+FIRD FLRISTA+GDG+HYCYPHFTCAVDTENIRRVFNDCRDIIQRM
Sbjct: 312 EPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRM 371

Query: 451 HLKQYELL 458
           HL+QYELL
Sbjct: 372 HLRQYELL 379


>gi|18426900 GNAS complex locus GNASS [Homo sapiens]
          Length = 380

 Score =  593 bits (1528), Expect = e-169
 Identities = 281/369 (76%), Positives = 326/369 (88%), Gaps = 1/369 (0%)

Query: 91  EREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE 150
           +R   K  R+ ++ I++ L+  K+  + THRLLLLGAGESGKSTIVKQMRILHVNGFN +
Sbjct: 12  QRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGD 71

Query: 151 -EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQE 209
            EK  K+ DI+ N+K+AI TIV+AMS ++PPV LANPENQFR DYI S+  + DF++  E
Sbjct: 72  SEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPE 131

Query: 210 FFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTS 269
           F++H K LW+DEGV+AC+ERSNEYQLIDCAQYFL++ID +   DY P+DQDLLRCRVLTS
Sbjct: 132 FYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTS 191

Query: 270 GIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNR 329
           GIFET+FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAII+V A SSYNMVIREDN TNR
Sbjct: 192 GIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNR 251

Query: 330 LRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDAT 389
           L+E+L+LF+SIWNNRWLRTIS+ILFLNKQD+LAEKVLAGKSKIEDYFPE+A YT PEDAT
Sbjct: 252 LQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDAT 311

Query: 390 PDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQR 449
           P+ GEDP+VTRAK+FIRD FLRISTA+GDG+HYCYPHFTCAVDTENIRRVFNDCRDIIQR
Sbjct: 312 PEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQR 371

Query: 450 MHLKQYELL 458
           MHL+QYELL
Sbjct: 372 MHLRQYELL 380


>gi|4504047 GNAS complex locus GNASL [Homo sapiens]
          Length = 394

 Score =  588 bits (1517), Expect = e-168
 Identities = 282/383 (73%), Positives = 326/383 (85%), Gaps = 15/383 (3%)

Query: 91  EREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE 150
           +R   K  R+ ++ I++ L+  K+  + THRLLLLGAGESGKSTIVKQMRILHVNGFN E
Sbjct: 12  QRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGE 71

Query: 151 ---------------EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYI 195
                          EK  K+ DI+ N+K+AI TIV+AMS ++PPV LANPENQFR DYI
Sbjct: 72  GGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYI 131

Query: 196 KSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYT 255
            S+  + DF++  EF++H K LW+DEGV+AC+ERSNEYQLIDCAQYFL++ID +   DY 
Sbjct: 132 LSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYV 191

Query: 256 PTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACS 315
           P+DQDLLRCRVLTSGIFET+FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAII+V A S
Sbjct: 192 PSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASS 251

Query: 316 SYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDY 375
           SYNMVIREDN TNRL+E+L+LF+SIWNNRWLRTIS+ILFLNKQD+LAEKVLAGKSKIEDY
Sbjct: 252 SYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDY 311

Query: 376 FPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTEN 435
           FPE+A YT PEDATP+ GEDP+VTRAK+FIRD FLRISTA+GDG+HYCYPHFTCAVDTEN
Sbjct: 312 FPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTEN 371

Query: 436 IRRVFNDCRDIIQRMHLKQYELL 458
           IRRVFNDCRDIIQRMHL+QYELL
Sbjct: 372 IRRVFNDCRDIIQRMHLRQYELL 394


>gi|117938762 GNAS complex locus isoform f [Homo sapiens]
          Length = 395

 Score =  588 bits (1516), Expect = e-168
 Identities = 282/384 (73%), Positives = 326/384 (84%), Gaps = 16/384 (4%)

Query: 91  EREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE 150
           +R   K  R+ ++ I++ L+  K+  + THRLLLLGAGESGKSTIVKQMRILHVNGFN E
Sbjct: 12  QRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGE 71

Query: 151 ----------------EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDY 194
                           EK  K+ DI+ N+K+AI TIV+AMS ++PPV LANPENQFR DY
Sbjct: 72  GGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 131

Query: 195 IKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDY 254
           I S+  + DF++  EF++H K LW+DEGV+AC+ERSNEYQLIDCAQYFL++ID +   DY
Sbjct: 132 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 191

Query: 255 TPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAAC 314
            P+DQDLLRCRVLTSGIFET+FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAII+V A 
Sbjct: 192 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 251

Query: 315 SSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIED 374
           SSYNMVIREDN TNRL+E+L+LF+SIWNNRWLRTIS+ILFLNKQD+LAEKVLAGKSKIED
Sbjct: 252 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 311

Query: 375 YFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTE 434
           YFPE+A YT PEDATP+ GEDP+VTRAK+FIRD FLRISTA+GDG+HYCYPHFTCAVDTE
Sbjct: 312 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 371

Query: 435 NIRRVFNDCRDIIQRMHLKQYELL 458
           NIRRVFNDCRDIIQRMHL+QYELL
Sbjct: 372 NIRRVFNDCRDIIQRMHLRQYELL 395


>gi|40254462 guanine nucleotide binding protein (G protein), q
           polypeptide [Homo sapiens]
          Length = 359

 Score =  277 bits (709), Expect = 1e-74
 Identities = 149/366 (40%), Positives = 219/366 (59%), Gaps = 19/366 (5%)

Query: 93  EAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEK 152
           E  KEAR+++  I+R LR  KRD ++  +LLLLG GESGKST +KQMRI+H +G++ E+K
Sbjct: 13  EEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDK 72

Query: 153 KQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFD 212
           +     + +N+  A+  ++ AM T+   +P     N+  +  ++ +       +   + D
Sbjct: 73  RGFTKLVYQNIFTAMQAMIRAMDTL--KIPYKYEHNKAHAQLVREVDVEKVSAFENPYVD 130

Query: 213 HVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIF 272
            +K LW+D G++ C++R  EYQL D  +Y+L  +D V+   Y PT QD+LR RV T+GI 
Sbjct: 131 AIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGII 190

Query: 273 ETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRE 332
           E  F +  V F M DVGGQR ERRKWI CF +VT+I+++ A S Y+ V+ E +N NR+ E
Sbjct: 191 EYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEE 250

Query: 333 SLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDA 392
           S  LF +I    W +  S+ILFLNK+D+L EK++   S + DYFPEY             
Sbjct: 251 SKALFRTIITYPWFQNSSVILFLNKKDLLEEKIM--YSHLVDYFPEY------------D 296

Query: 393 GEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHL 452
           G       A+ FI  +F+ ++    D     Y HFTCA DTENIR VF   +D I +++L
Sbjct: 297 GPQRDAQAAREFILKMFVDLNP---DSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNL 353

Query: 453 KQYELL 458
           K+Y L+
Sbjct: 354 KEYNLV 359


>gi|115511049 guanine nucleotide binding protein (G protein), alpha
           11 (Gq class) [Homo sapiens]
          Length = 359

 Score =  272 bits (695), Expect = 5e-73
 Identities = 148/380 (38%), Positives = 230/380 (60%), Gaps = 23/380 (6%)

Query: 81  LSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMR 140
           ++ E   A    + VKE+++++  I++ LR  KRD ++  +LLLLG GESGKST +KQMR
Sbjct: 1   MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR 60

Query: 141 ILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSI-- 198
           I+H  G++ E+K+     + +N+  A+  ++ AM T+   +     +N+  +  I+ +  
Sbjct: 61  IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETL--KILYKYEQNKANALLIREVDV 118

Query: 199 APITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTD 258
             +T FE+  ++   +K LW+D G++ C++R  EYQL D A+Y+L  +D ++ + Y PT 
Sbjct: 119 EKVTTFEH--QYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQ 176

Query: 259 QDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYN 318
           QD+LR RV T+GI E  F ++ + F M DVGGQR ERRKWI CF +VT+I+++ A S Y+
Sbjct: 177 QDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYD 236

Query: 319 MVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPE 378
            V+ E +N NR+ ES  LF +I    W +  S+ILFLNK+D+L +K+L   S + DYFPE
Sbjct: 237 QVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKIL--YSHLVDYFPE 294

Query: 379 YANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRR 438
           +             G       A+ FI  +F+ ++    D     Y HFTCA DTENIR 
Sbjct: 295 F------------DGPQRDAQAAREFILKMFVDLNP---DSDKIIYSHFTCATDTENIRF 339

Query: 439 VFNDCRDIIQRMHLKQYELL 458
           VF   +D I +++LK+Y L+
Sbjct: 340 VFAAVKDTILQLNLKEYNLV 359


>gi|4758444 G alpha 14 [Homo sapiens]
          Length = 355

 Score =  266 bits (679), Expect = 4e-71
 Identities = 149/378 (39%), Positives = 223/378 (58%), Gaps = 29/378 (7%)

Query: 81  LSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMR 140
           LSAEE          KE++++S  I+R LR  K+D ++  +LLLLG GESGKST +KQMR
Sbjct: 7   LSAEE----------KESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMR 56

Query: 141 ILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP 200
           I+H +G++ E++K     + +N+  A+  ++ AM T+   +     +N+  +  I+ +  
Sbjct: 57  IIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTL--RIQYVCEQNKENAQIIREVEV 114

Query: 201 ITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQD 260
                 S+E  + +K+LW D G++ C++R  EYQL D A+Y+L  ID ++   + PT QD
Sbjct: 115 DKVSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQD 174

Query: 261 LLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMV 320
           +LR RV T+GI E  F ++ + F M DVGGQR ERRKWI CF  VT+II++ A S Y+ V
Sbjct: 175 VLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQV 234

Query: 321 IREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYA 380
           + E +N NR+ ES  LF++I    W    S+ILFLNK+D+L EK++   S +  YFPEY 
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIM--YSHLISYFPEY- 291

Query: 381 NYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVF 440
                       G    V  A+ FI  L+        D +   Y HFTCA DT+NIR VF
Sbjct: 292 -----------TGPKQDVRAARDFILKLY---QDQNPDKEKVIYSHFTCATDTDNIRFVF 337

Query: 441 NDCRDIIQRMHLKQYELL 458
              +D I +++L+++ L+
Sbjct: 338 AAVKDTILQLNLREFNLV 355


>gi|156139155 guanine nucleotide binding protein, alpha transducing
           3 [Homo sapiens]
          Length = 354

 Score =  266 bits (679), Expect = 4e-71
 Identities = 151/359 (42%), Positives = 221/359 (61%), Gaps = 20/359 (5%)

Query: 96  KEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 155
           KE+ K S+ +++ L++      +T +LLLLGAGESGKSTIVKQM+I+H NG++ +E  + 
Sbjct: 10  KESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEF 69

Query: 156 ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIA-PITDFEYSQEFFDHV 214
              I  N   +I+ IV AM+T+   +   NP +      + ++A  + D   + +  + +
Sbjct: 70  KAVIYSNTLQSILAIVKAMTTL--GIDYVNPRSAEDQRQLYAMANTLEDGGMTPQLAEVI 127

Query: 215 KKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFET 274
           K+LW D G++ACFER++EYQL D A Y+L  +D ++   Y P +QD+L  RV T+GI ET
Sbjct: 128 KRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIET 187

Query: 275 RFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESL 334
           +F    ++F MFDVGGQR ER+KWI CF  VT II+ AA S+Y+MV+ ED   NR+ ESL
Sbjct: 188 QFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESL 247

Query: 335 DLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGE 394
            LF SI N+++  T SI+LFLNK+D+  EKV   K  +   FPEY          P+  E
Sbjct: 248 HLFNSICNHKYFSTTSIVLFLNKKDIFQEKVT--KVHLSICFPEYTG--------PNTFE 297

Query: 395 DPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLK 453
           D     A  +I++ FL ++    D +   Y H TCA DT+N++ VF+   DII + +LK
Sbjct: 298 D-----AGNYIKNQFLDLNLKKEDKE--IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349


>gi|20330805 guanine nucleotide binding protein, alpha transducing
           activity polypeptide 2 [Homo sapiens]
          Length = 354

 Score =  265 bits (676), Expect = 8e-71
 Identities = 153/359 (42%), Positives = 223/359 (62%), Gaps = 20/359 (5%)

Query: 96  KEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 155
           KE  K S+ +++ L++      +T +LLLLGAGESGKSTIVKQM+I+H +G++PEE  + 
Sbjct: 10  KELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEF 69

Query: 156 ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP-ITDFEYSQEFFDHV 214
              I  NV  +I+ I+ AM+T+   +  A P        + ++A  I +     E  + +
Sbjct: 70  KAIIYGNVLQSILAIIRAMTTL--GIDYAEPSCADDGRQLNNLADSIEEGTMPPELVEVI 127

Query: 215 KKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFET 274
           ++LW D GV+ACFER+ EYQL D A Y+L +++ ++  +Y P++QD+LR RV T+GI ET
Sbjct: 128 RRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVKTTGIIET 187

Query: 275 RFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESL 334
           +F V  +NF MFDVGGQR ER+KWI CF  VT II+ AA S+Y+MV+ ED+  NR+ ESL
Sbjct: 188 KFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESL 247

Query: 335 DLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGE 394
            LF SI N+++    SI+LFLNK+D+  EK+   K  +   FPEY       ++  DAG 
Sbjct: 248 HLFNSICNHKFFAATSIVLFLNKKDLFEEKI--KKVHLSICFPEYDG----NNSYDDAGN 301

Query: 395 DPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLK 453
                    +I+  FL ++    D K   Y H TCA DT+N++ VF+   DII + +LK
Sbjct: 302 ---------YIKSQFLDLNMRK-DVKE-IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349


>gi|162461738 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform b [Homo sapiens]
          Length = 354

 Score =  264 bits (674), Expect = 1e-70
 Identities = 158/375 (42%), Positives = 217/375 (57%), Gaps = 32/375 (8%)

Query: 81  LSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMR 140
           LSAEER AA ER         S+ I++ L++      +  +LLLLGAGESGKSTIVKQM+
Sbjct: 5   LSAEER-AALER---------SKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMK 54

Query: 141 ILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP 200
           I+H +GF+ E+ KQ    +  N   ++  IV AM T+   +   + E +  +  +  +  
Sbjct: 55  IIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTL--GIEYGDKERKADAKMVCDVVS 112

Query: 201 -ITDFE-YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTD 258
            + D E +S E    + +LW D G++ CF RS EYQL D A+Y+L+ +D +   DY PT+
Sbjct: 113 RMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTE 172

Query: 259 QDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYN 318
           QD+LR RV T+GI ET F    ++F +FDVGGQR ER+KWI CF DVTAII+  A S Y+
Sbjct: 173 QDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYD 232

Query: 319 MVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPE 378
            V+ ED  TNR+ ESL LF+SI NN+W    SIILFLNK+D+  EK+   KS +   FPE
Sbjct: 233 QVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKI--KKSPLTICFPE 290

Query: 379 YANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRR 438
           Y          P A      T A  +I+    +  +         Y H TCA DT NI+ 
Sbjct: 291 YTG--------PSA-----FTEAVAYIQ---AQYESKNKSAHKEIYTHVTCATDTNNIQF 334

Query: 439 VFNDCRDIIQRMHLK 453
           VF+   D+I   +L+
Sbjct: 335 VFDAVTDVIIAKNLR 349


>gi|33946324 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 1 [Homo sapiens]
          Length = 354

 Score =  262 bits (670), Expect = 4e-70
 Identities = 160/373 (42%), Positives = 217/373 (58%), Gaps = 28/373 (7%)

Query: 81  LSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMR 140
           LSAE++ AA ER         S+ IDR LR+      +  +LLLLGAGESGKSTIVKQM+
Sbjct: 5   LSAEDK-AAVER---------SKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMK 54

Query: 141 ILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP 200
           I+H  G++ EE KQ    +  N   +I+ I+ AM  +      +   +  R  ++ + A 
Sbjct: 55  IIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAA 114

Query: 201 ITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQD 260
              F  + E    +K+LW D GV+ACF RS EYQL D A Y+L  +D ++  +Y PT QD
Sbjct: 115 EEGF-MTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQD 173

Query: 261 LLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMV 320
           +LR RV T+GI ET F    ++F MFDVGGQR ER+KWI CF  VTAII+  A S Y++V
Sbjct: 174 VLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLV 233

Query: 321 IREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYA 380
           + ED   NR+ ES+ LF+SI NN+W    SIILFLNK+D+  EK+   KS +   +PEYA
Sbjct: 234 LAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKI--KKSPLTICYPEYA 291

Query: 381 NYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVF 440
                E+A           + +F   DL  R  T         Y HFTCA DT+N++ VF
Sbjct: 292 GSNTYEEAA-------AYIQCQF--EDLNKRKDTKE------IYTHFTCATDTKNVQFVF 336

Query: 441 NDCRDIIQRMHLK 453
           +   D+I + +LK
Sbjct: 337 DAVTDVIIKNNLK 349


>gi|10567816 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform a [Homo sapiens]
          Length = 354

 Score =  262 bits (669), Expect = 5e-70
 Identities = 159/375 (42%), Positives = 219/375 (58%), Gaps = 32/375 (8%)

Query: 81  LSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMR 140
           LSAEER AA ER         S+ I++ L++      +  +LLLLGAGESGKSTIVKQM+
Sbjct: 5   LSAEER-AALER---------SKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMK 54

Query: 141 ILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP 200
           I+H +GF+ E+ KQ    +  N   ++  IV AM T+   +   + E +  +  +  +  
Sbjct: 55  IIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTL--GIEYGDKERKADAKMVCDVVS 112

Query: 201 -ITDFE-YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTD 258
            + D E +S E    + +LW D G++ CF RS EYQL D A+Y+L+ +D +   DY PT+
Sbjct: 113 RMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTE 172

Query: 259 QDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYN 318
           QD+LR RV T+GI ET F    ++F +FDVGGQR ER+KWI CF DVTAII+  A S Y+
Sbjct: 173 QDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYD 232

Query: 319 MVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPE 378
            V+ ED  TNR+ ESL LF+SI NN++    SIILFLNK+D+  EK+   KS +   FPE
Sbjct: 233 QVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKI--KKSPLTICFPE 290

Query: 379 YANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRR 438
           Y      EDA           +A+F            + + + YC  H TCA DT NI+ 
Sbjct: 291 YTGPNTYEDAA-------AYIQAQF-------ESKNRSPNKEIYC--HMTCATDTNNIQV 334

Query: 439 VFNDCRDIIQRMHLK 453
           VF+   DII   +L+
Sbjct: 335 VFDAVTDIIIANNLR 349


>gi|22027522 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  261 bits (668), Expect = 7e-70
 Identities = 152/355 (42%), Positives = 219/355 (61%), Gaps = 20/355 (5%)

Query: 100 KVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDI 159
           K SR +++ L++      +T +LLLLGAGESGKSTIVKQM+I+H +G++ EE  + I  I
Sbjct: 10  KHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAII 69

Query: 160 RKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP-ITDFEYSQEFFDHVKKLW 218
             N   +I+ IV AM+T+   +   +   Q  +  +  +A  I +    +E  D +++LW
Sbjct: 70  YGNTLQSILAIVRAMTTL--NIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLW 127

Query: 219 DDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQV 278
            D G++ACFER++EYQL D A Y+L  ++ +    Y PT+QD+LR RV T+GI ET+F  
Sbjct: 128 KDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSF 187

Query: 279 DKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFE 338
             +NF MFDVGGQR ER+KWI CF  VT II++AA S+Y+MV+ ED+  NR+ ESL LF 
Sbjct: 188 KDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFN 247

Query: 339 SIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKV 398
           SI N+R+  T SI+LFLNK+D+  EK+   K+ +   FP+Y      EDA          
Sbjct: 248 SICNHRYFATTSIVLFLNKKDVFFEKI--KKAHLSICFPDYDGPNTYEDAGN-------- 297

Query: 399 TRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLK 453
                +I+  FL ++    D K   Y H TCA DT+N++ VF+   DII + +LK
Sbjct: 298 -----YIKVQFLELNMRR-DVKE-IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 345


>gi|22027520 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  261 bits (668), Expect = 7e-70
 Identities = 152/355 (42%), Positives = 219/355 (61%), Gaps = 20/355 (5%)

Query: 100 KVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDI 159
           K SR +++ L++      +T +LLLLGAGESGKSTIVKQM+I+H +G++ EE  + I  I
Sbjct: 10  KHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAII 69

Query: 160 RKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP-ITDFEYSQEFFDHVKKLW 218
             N   +I+ IV AM+T+   +   +   Q  +  +  +A  I +    +E  D +++LW
Sbjct: 70  YGNTLQSILAIVRAMTTL--NIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLW 127

Query: 219 DDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQV 278
            D G++ACFER++EYQL D A Y+L  ++ +    Y PT+QD+LR RV T+GI ET+F  
Sbjct: 128 KDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSF 187

Query: 279 DKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFE 338
             +NF MFDVGGQR ER+KWI CF  VT II++AA S+Y+MV+ ED+  NR+ ESL LF 
Sbjct: 188 KDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFN 247

Query: 339 SIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKV 398
           SI N+R+  T SI+LFLNK+D+  EK+   K+ +   FP+Y      EDA          
Sbjct: 248 SICNHRYFATTSIVLFLNKKDVFFEKI--KKAHLSICFPDYDGPNTYEDAGN-------- 297

Query: 399 TRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLK 453
                +I+  FL ++    D K   Y H TCA DT+N++ VF+   DII + +LK
Sbjct: 298 -----YIKVQFLELNMRR-DVKE-IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 345


>gi|5729850 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 3 [Homo sapiens]
          Length = 354

 Score =  259 bits (663), Expect = 3e-69
 Identities = 157/374 (41%), Positives = 217/374 (58%), Gaps = 28/374 (7%)

Query: 81  LSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMR 140
           LSAE++ AA ER         S+ IDR LR+      +  +LLLLGAGESGKSTIVKQM+
Sbjct: 5   LSAEDK-AAVER---------SKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMK 54

Query: 141 ILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP 200
           I+H +G++ +E KQ  + +  N   +I+ I+ AM  +      A   +  R  ++ +   
Sbjct: 55  IIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLA-GS 113

Query: 201 ITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQD 260
             +   + E    +K+LW D GV+ACF RS EYQL D A Y+L  +D +S  +Y PT QD
Sbjct: 114 AEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQD 173

Query: 261 LLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMV 320
           +LR RV T+GI ET F    + F MFDVGGQR ER+KWI CF  VTAII+  A S Y++V
Sbjct: 174 VLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLV 233

Query: 321 IREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYA 380
           + ED   NR+ ES+ LF+SI NN+W    SIILFLNK+D+  EK+   +S +   +PEY 
Sbjct: 234 LAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKI--KRSPLTICYPEYT 291

Query: 381 NYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVF 440
                E+A           + +F   DL  R  T         Y HFTCA DT+N++ VF
Sbjct: 292 GSNTYEEAA-------AYIQCQF--EDLNRRKDTKE------IYTHFTCATDTKNVQFVF 336

Query: 441 NDCRDIIQRMHLKQ 454
           +   D+I + +LK+
Sbjct: 337 DAVTDVIIKNNLKE 350


>gi|4504041 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 2 [Homo sapiens]
          Length = 355

 Score =  259 bits (661), Expect = 5e-69
 Identities = 152/363 (41%), Positives = 214/363 (58%), Gaps = 27/363 (7%)

Query: 96  KEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK 155
           K A + S+ ID+ LR+      +  +LLLLGAGESGKSTIVKQM+I+H +G++ EE +Q 
Sbjct: 10  KAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQY 69

Query: 156 ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQ-----EF 210
              +  N   +I+ IV AM  +   +  A+P    R+D  + +  ++     Q     + 
Sbjct: 70  RAVVYSNTIQSIMAIVKAMGNL--QIDFADPS---RADDARQLFALSCTAEEQGVLPDDL 124

Query: 211 FDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSG 270
              +++LW D GV+ACF RS EYQL D A Y+L  ++ ++  DY PT QD+LR RV T+G
Sbjct: 125 SGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTG 184

Query: 271 IFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRL 330
           I ET F    ++F MFDVGGQR ER+KWI CF  VTAII+  A S+Y++V+ ED   NR+
Sbjct: 185 IVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRM 244

Query: 331 RESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATP 390
            ES+ LF+SI NN+W    SIILFLNK+D+  EK+    S +   FPEY      ++A  
Sbjct: 245 HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIT--HSPLTICFPEYTGANKYDEAA- 301

Query: 391 DAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRM 450
                    ++KF   DL  R  T         Y HFTCA DT+N++ VF+   D+I + 
Sbjct: 302 ------SYIQSKF--EDLNKRKDTKE------IYTHFTCATDTKNVQFVFDAVTDVIIKN 347

Query: 451 HLK 453
           +LK
Sbjct: 348 NLK 350


>gi|156104883 guanine nucleotide binding protein (G protein), alpha
           15 (Gq class) [Homo sapiens]
          Length = 374

 Score =  252 bits (644), Expect = 4e-67
 Identities = 140/375 (37%), Positives = 215/375 (57%), Gaps = 25/375 (6%)

Query: 93  EAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEK 152
           E  K A +V + I+R+L +QK+  +   +LLLLG GESGKST +KQMRI+H  G++ EE+
Sbjct: 16  EDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEER 75

Query: 153 KQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFD 212
           K     + +N+  ++  ++ AM  +   +P + PE++  +  + S  P     + + +  
Sbjct: 76  KGFRPLVYQNIFVSMRAMIEAMERL--QIPFSRPESKHHASLVMSQDPYKVTTFEKRYAA 133

Query: 213 HVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIF 272
            ++ LW D G++A +ER  E+ L+D A Y+L  ++ ++   Y PT QD+LR R+ T+GI 
Sbjct: 134 AMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGIN 193

Query: 273 ETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRE 332
           E  F V K N  + DVGGQ+ ER+KWI CF +V A+IY+A+ S Y+  + E+N  NR++E
Sbjct: 194 EYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKE 253

Query: 333 SLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDA 392
           SL LF +I    W ++ S+ILFLNK D+L EK+    S +  YFP +             
Sbjct: 254 SLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLATYFPSF------------Q 299

Query: 393 GEDPKVTRAKFFIRDLFLRISTATGDG---------KHYCYPHFTCAVDTENIRRVFNDC 443
           G       AK FI D++ R+ T   DG             + H+TCA DT+NIR+VF D 
Sbjct: 300 GPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDV 359

Query: 444 RDIIQRMHLKQYELL 458
           RD +   +L +  LL
Sbjct: 360 RDSVLARYLDEINLL 374


>gi|4504051 guanine nucleotide binding protein, alpha z polypeptide
           [Homo sapiens]
          Length = 355

 Score =  247 bits (630), Expect = 2e-65
 Identities = 143/370 (38%), Positives = 215/370 (58%), Gaps = 25/370 (6%)

Query: 86  REAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVN 145
           R++++E+EA + +R+    IDR LR + +  ++  +LLLLG   SGKSTIVKQM+I+H  
Sbjct: 4   RQSSEEKEAARRSRR----IDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSG 59

Query: 146 GFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDF- 204
           GFN E  K+    I  N  D++  I+ A++ +   +   NP+  + +  + ++    +  
Sbjct: 60  GFNLEACKEYKPLIIYNAIDSLTRIIRALAAL--RIDFHNPDRAYDAVQLFALTGPAESK 117

Query: 205 -EYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLR 263
            E + E    +++LW D G +ACF RS+EY L D A Y+L  ++ ++  DY PT +D+LR
Sbjct: 118 GEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILR 177

Query: 264 CRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIRE 323
            R +T+GI E +F   ++ F M DVGGQR ER+KWI CF  VTAII+    S Y++ + E
Sbjct: 178 SRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYE 237

Query: 324 DNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYT 383
           DN T+R+ ESL LF+SI NN W    S+ILFLNK+D+LAEK+   +  +   FPEY    
Sbjct: 238 DNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKI--RRIPLTICFPEYKGQN 295

Query: 384 VPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDC 443
             E+A               +I+  F  ++          Y HFTCA DT NI+ VF+  
Sbjct: 296 TYEEAA-------------VYIQRQFEDLN--RNKETKEIYSHFTCATDTSNIQFVFDAV 340

Query: 444 RDIIQRMHLK 453
            D+I + +LK
Sbjct: 341 TDVIIQNNLK 350


>gi|42476111 guanine nucleotide binding protein (G protein) alpha 12
           [Homo sapiens]
          Length = 381

 Score =  228 bits (582), Expect = 7e-60
 Identities = 139/383 (36%), Positives = 217/383 (56%), Gaps = 33/383 (8%)

Query: 84  EEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILH 143
           E R  +  R+A +EAR+ SR ID +L  ++R +++  ++LLLGAGESGKST +KQMRI+H
Sbjct: 22  ERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH 81

Query: 144 VNGFNPEEKKQKILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI---- 195
              F+    ++ +L+ R  + D I+     +V A   +   +P    EN+    ++    
Sbjct: 82  GREFD----QKALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFE 135

Query: 196 -KSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDY 254
            K+  P+    + Q +   +  LW D G++  F R +E+QL +  +YFL+ +D +  ++Y
Sbjct: 136 NKAGLPVEPATF-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNY 194

Query: 255 TPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAAC 314
            P+ QD+L  R  T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + 
Sbjct: 195 FPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSS 254

Query: 315 SSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIED 374
           S Y+ V+ ED  TNRL ES+++FE+I NN+    +SIILFLNK D+L EKV      I+ 
Sbjct: 255 SEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKK 312

Query: 375 YFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTE 434
           +FP++          P   ED +    + F R    R            + HFT A+DTE
Sbjct: 313 HFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTE 357

Query: 435 NIRRVFNDCRDIIQRMHLKQYEL 457
           N+R VF+  +D I + +LK   L
Sbjct: 358 NVRFVFHAVKDTILQENLKDIML 380


>gi|24111250 guanine nucleotide binding protein (G protein), alpha
           13 [Homo sapiens]
          Length = 377

 Score =  225 bits (573), Expect = 7e-59
 Identities = 137/370 (37%), Positives = 207/370 (55%), Gaps = 28/370 (7%)

Query: 97  EARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKI 156
           E ++ S+ ID+ L  +K  +++  ++LLLGAGESGKST +KQMRI+H   F+   +++  
Sbjct: 26  EQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFR 85

Query: 157 LDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSI---APIT-----DFEYSQ 208
             I  NV   +  +V A   +   +P  +  NQ   D + S    AP+      +     
Sbjct: 86  PTIYSNVIKGMRVLVDAREKL--HIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143

Query: 209 EFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLT 268
           ++   ++ LW D G++  ++R  E+QL +  +YFL+ +D +   DY P+ QD+L  R  T
Sbjct: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203

Query: 269 SGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTN 328
            GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+++ + S ++ V+ ED  TN
Sbjct: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263

Query: 329 RLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDA 388
           RL ESL++FE+I NNR    +SIILFLNK D+L EKV      I+DYF E+         
Sbjct: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFEG------- 314

Query: 389 TPDAGEDPKVTR-AKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDII 447
                 DP   R  + F+ + F   +      +   Y HFT A++TENIR VF D +D I
Sbjct: 315 ------DPHCLRDVQKFLVECFR--NKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTI 366

Query: 448 QRMHLKQYEL 457
              +LKQ  L
Sbjct: 367 LHDNLKQLML 376


>gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]
          Length = 175

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 10/80 (12%)

Query: 281 VNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESI 340
           V F+++DVGGQ   R  W   +     +I+V  C+          + +R+ E+      I
Sbjct: 57  VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCA----------DRDRIDEARQELHRI 106

Query: 341 WNNRWLRTISIILFLNKQDM 360
            N+R +R   I++F NKQD+
Sbjct: 107 INDREMRDAIILIFANKQDL 126


>gi|4502209 ADP-ribosylation factor 5 [Homo sapiens]
          Length = 180

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 268 TSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNT 327
           T G      +   + F ++DVGGQ   R  W   F +   +I+V           + N+ 
Sbjct: 48  TIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVV----------DSNDR 97

Query: 328 NRLRESLDLFESIWNNRWLRTISIILFLNKQDM 360
            R++ES D  + +     LR   +++F NKQDM
Sbjct: 98  ERVQESADELQKMLQEDELRDAVLLVFANKQDM 130


>gi|13376574 ADP-ribosylation factor-like 14 [Homo sapiens]
          Length = 192

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 10/76 (13%)

Query: 285 MFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNR 344
           ++DVGGQ   R  W     +   ++YV           +  +  RL ES   FE I  N 
Sbjct: 62  VWDVGGQEKMRTVWGCYCENTDGLVYVV----------DSTDKQRLEESQRQFEHILKNE 111

Query: 345 WLRTISIILFLNKQDM 360
            ++ + ++L  NKQDM
Sbjct: 112 HIKNVPVVLLANKQDM 127


>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
           sapiens]
          Length = 837

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 32/99 (32%), Positives = 40/99 (40%), Gaps = 4/99 (4%)

Query: 8   RPLLFGGPGDDPCAASEP---PVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGSPA-C 63
           RPL    P   P  A  P   P+    PAPAPA A   A +  T    +  GG GS    
Sbjct: 17  RPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDP 76

Query: 64  ARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVS 102
           ARP   + +   QR  Q+    R    E+  V  A K +
Sbjct: 77  ARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKAN 115


>gi|59853162 thymine-DNA glycosylase [Homo sapiens]
          Length = 410

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 23  SEPPVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGSPACARPKADKPKEKRQRTEQLS 82
           +E  + +  PAPAPA  PV+ A         P+G +  P    PK  +P E ++  E   
Sbjct: 36  NEQQMPEEVPAPAPAQEPVQEA---------PKGRKRKPRTTEPK--QPVEPKKPVESKK 84

Query: 83  AEEREAAKER-EAVKEARKVSRGIDR 107
           + +   +KE+ E + +  KV R +DR
Sbjct: 85  SGKSAKSKEKQEKITDTFKVKRKVDR 110


>gi|197927203 ADP-ribosylation factor related protein 1 isoform b
           [Homo sapiens]
          Length = 173

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 268 TSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNT 327
           T G+      V K     +D+GGQ + +  W + + +   +IYV           +  + 
Sbjct: 56  TVGLNIGTVDVGKARLMFWDLGGQEELQSLWDKYYAECHGVIYVI----------DSTDE 105

Query: 328 NRLRESLDLFESIWNNRWLRTISIILFLNKQDM 360
            RL ES   FE +  +  L  + +++  NKQD+
Sbjct: 106 ERLAESKQAFEKVVTSEALCGVPVLVLANKQDV 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,151,085
Number of Sequences: 37866
Number of extensions: 867340
Number of successful extensions: 6763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 5867
Number of HSP's gapped (non-prelim): 901
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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