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Search of human proteins with 33620716
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
sapiens]
(1758 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 3545 0.0
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 3528 0.0
gi|28077093 retinoblastoma-binding protein 6 isoform 3 [Homo sap... 205 4e-52
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 117 1e-25
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 114 8e-25
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 109 2e-23
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 109 2e-23
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 108 6e-23
gi|87299628 biorientation of chromosomes in cell division 1-like... 104 7e-22
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 103 1e-21
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 102 3e-21
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 101 7e-21
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 100 2e-20
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 100 2e-20
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 98 6e-20
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 98 8e-20
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 97 1e-19
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 97 1e-19
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 97 1e-19
gi|150170670 piccolo isoform 2 [Homo sapiens] 94 9e-19
gi|150378539 piccolo isoform 1 [Homo sapiens] 94 9e-19
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 92 3e-18
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 91 8e-18
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 85 5e-16
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 85 7e-16
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 84 9e-16
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 84 2e-15
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 82 4e-15
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 82 5e-15
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 82 5e-15
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 3545 bits (9193), Expect = 0.0
Identities = 1758/1758 (100%), Positives = 1758/1758 (100%)
Query: 1 MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD 60
MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD
Sbjct: 1 MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD 60
Query: 61 NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL 120
NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL
Sbjct: 61 NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL 120
Query: 121 AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK 180
AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK
Sbjct: 121 AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK 180
Query: 181 NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP 240
NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP
Sbjct: 181 NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP 240
Query: 241 EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH 300
EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH
Sbjct: 241 EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH 300
Query: 301 QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS 360
QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS
Sbjct: 301 QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS 360
Query: 361 PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV 420
PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV
Sbjct: 361 PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV 420
Query: 421 HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL 480
HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL
Sbjct: 421 HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL 480
Query: 481 HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE 540
HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE
Sbjct: 481 HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE 540
Query: 541 RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP 600
RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP
Sbjct: 541 RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP 600
Query: 601 PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSS 660
PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSS
Sbjct: 601 PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSS 660
Query: 661 YSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYH 720
YSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYH
Sbjct: 661 YSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYH 720
Query: 721 RSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGR 780
RSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGR
Sbjct: 721 RSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGR 780
Query: 781 SVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSP 840
SVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSP
Sbjct: 781 SVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSP 840
Query: 841 FTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK 900
FTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK
Sbjct: 841 FTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK 900
Query: 901 KHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAE 960
KHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAE
Sbjct: 901 KHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAE 960
Query: 961 SITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR 1020
SITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR
Sbjct: 961 SITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR 1020
Query: 1021 SEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY 1080
SEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY
Sbjct: 1021 SEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY 1080
Query: 1081 SKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTE 1140
SKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTE
Sbjct: 1081 SKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTE 1140
Query: 1141 IVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK 1200
IVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK
Sbjct: 1141 IVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK 1200
Query: 1201 LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIK 1260
LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIK
Sbjct: 1201 LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIK 1260
Query: 1261 TMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVST 1320
TMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVST
Sbjct: 1261 TMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVST 1320
Query: 1321 KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKE 1380
KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKE
Sbjct: 1321 KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKE 1380
Query: 1381 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1440
NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK
Sbjct: 1381 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1440
Query: 1441 TDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNS 1500
TDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNS
Sbjct: 1441 TDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNS 1500
Query: 1501 SPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPP 1560
SPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPP
Sbjct: 1501 SPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPP 1560
Query: 1561 ETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKE 1620
ETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKE
Sbjct: 1561 ETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKE 1620
Query: 1621 EESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSH 1680
EESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSH
Sbjct: 1621 EESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSH 1680
Query: 1681 SSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1740
SSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK
Sbjct: 1681 SSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1740
Query: 1741 DKEKEKEKDDQKVKSVTV 1758
DKEKEKEKDDQKVKSVTV
Sbjct: 1741 DKEKEKEKDDQKVKSVTV 1758
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 3528 bits (9148), Expect = 0.0
Identities = 1758/1792 (98%), Positives = 1758/1792 (98%), Gaps = 34/1792 (1%)
Query: 1 MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD 60
MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD
Sbjct: 1 MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD 60
Query: 61 NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL 120
NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL
Sbjct: 61 NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL 120
Query: 121 AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK 180
AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK
Sbjct: 121 AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK 180
Query: 181 NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP 240
NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP
Sbjct: 181 NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP 240
Query: 241 EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH 300
EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH
Sbjct: 241 EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH 300
Query: 301 QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS 360
QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS
Sbjct: 301 QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS 360
Query: 361 PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV 420
PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV
Sbjct: 361 PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV 420
Query: 421 HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL 480
HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL
Sbjct: 421 HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL 480
Query: 481 HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE 540
HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE
Sbjct: 481 HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE 540
Query: 541 RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP 600
RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP
Sbjct: 541 RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP 600
Query: 601 PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEE--------- 651
PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEE
Sbjct: 601 PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDE 660
Query: 652 -------------------------SKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFS 686
SKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFS
Sbjct: 661 FTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFS 720
Query: 687 RSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQS 746
RSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQS
Sbjct: 721 RSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQS 780
Query: 747 PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEK 806
PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEK
Sbjct: 781 PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEK 840
Query: 807 YYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPE 866
YYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPE
Sbjct: 841 YYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPE 900
Query: 867 KLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKS 926
KLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKS
Sbjct: 901 KLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKS 960
Query: 927 REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK 986
REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK
Sbjct: 961 REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK 1020
Query: 987 RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK 1046
RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK
Sbjct: 1021 RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK 1080
Query: 1047 DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPL 1106
DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPL
Sbjct: 1081 DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPL 1140
Query: 1107 DNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1166
DNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI
Sbjct: 1141 DNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1200
Query: 1167 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEG 1226
SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEG
Sbjct: 1201 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEG 1260
Query: 1227 SSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK 1286
SSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK
Sbjct: 1261 SSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK 1320
Query: 1287 WDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDV 1346
WDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDV
Sbjct: 1321 WDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDV 1380
Query: 1347 SHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF 1406
SHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF
Sbjct: 1381 SHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF 1440
Query: 1407 KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS 1466
KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS
Sbjct: 1441 KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS 1500
Query: 1467 PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526
PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS
Sbjct: 1501 PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1560
Query: 1527 VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH 1586
VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH
Sbjct: 1561 VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH 1620
Query: 1587 SSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTA 1646
SSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTA
Sbjct: 1621 SSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTA 1680
Query: 1647 AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1706
AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK
Sbjct: 1681 AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1740
Query: 1707 HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVTV 1758
HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVTV
Sbjct: 1741 HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVTV 1792
>gi|28077093 retinoblastoma-binding protein 6 isoform 3 [Homo
sapiens]
Length = 118
Score = 205 bits (521), Expect = 4e-52
Identities = 102/108 (94%), Positives = 105/108 (97%)
Query: 1 MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD 60
MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD
Sbjct: 1 MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD 60
Query: 61 NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSAS 108
NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKA+ ++ S
Sbjct: 61 NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAVCKNTIS 108
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 117 bits (293), Expect = 1e-25
Identities = 169/930 (18%), Positives = 326/930 (35%), Gaps = 63/930 (6%)
Query: 850 VGGQSHRSRNIGSNYPEKLSARDGHNQ------KDNTKSKEKESENAPGDGK----GNKH 899
+ G S +RNI + ++ Q K N K+ + E N G G+ GNK
Sbjct: 378 IKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKT-QGEVVNIEGPGQKSEPGNK- 435
Query: 900 KKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENK------TDSLFVLPSRDDATPVR 953
H S+G+ + + + S + +P +E+ ++S SR DA+
Sbjct: 436 VGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNS 495
Query: 954 DEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDG 1013
DE D + + +E D + D N+G+ + K + KG + D
Sbjct: 496 DESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD---SGKGKSDSSDS 552
Query: 1014 ERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
+ S S + ++ ++++ S SS D + + S ++ + ++ +
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1133
D S D KS+ + K + D+K + + + + D SS
Sbjct: 613 SSDSSD-SSDSKSD--------SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 1134 SKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISN 1193
+ + ++ S + D + D + S + + S+++ +
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS-----DSSDSSDSDSSDSSDS 718
Query: 1194 TKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTD 1253
+ S +S++S + + + SS + S++S+ S S + +D
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Query: 1254 TKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPAS 1313
+ + + ++ N++ + D S D +S + D S SS +S
Sbjct: 779 SSNS----SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD-SSNSSDSSNSSDSS 833
Query: 1314 VIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQ--HEVKSSKNSASSEKGKTKD 1371
N S + +S+ S + S + + SS +S S+E + D
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 1372 R-DYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSN 1430
D S + NS+ SN +E N S SS + +SD DS+ +S++
Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 1431 KDFTPNRDKKTDYDTREYSSSKRRDEKN--ELTRRKDSPSRNKDSASGQKNKPREERDLP 1488
D + + D D+ + +SS D N + + DS + S S + + D
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 1489 KKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES 1548
++S S D + D+ ++ + S D + D ++ ++ +S
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS----DSSDSSDS 1069
Query: 1549 SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN 1608
S + + + + + D S S SS SSD + +D + N
Sbjct: 1070 SDS------SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSN 1122
Query: 1609 ESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSR 1668
SDS + + S N S + +S D++ S + S SS S + S
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Query: 1669 SHSPSGSQTRSHSS-------SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV 1721
S S S S SS S+ S++S DS + + + +
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242
Query: 1722 ELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
+ S + + E D Q
Sbjct: 1243 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Score = 107 bits (266), Expect = 1e-22
Identities = 146/831 (17%), Positives = 295/831 (35%), Gaps = 42/831 (5%)
Query: 870 ARDGHNQKDNTKSKEKESENAP----GDGKGNKHKKHRKRRKGEESEGFLNPELLETSRK 925
++D N D+ +++ +S++ D GN + + K + +G + ++S
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 926 SREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKT 985
S + + +DS S D + D ++S + S + D + D +
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 986 KRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQ 1045
+ S SK E+ + + D S S+ ++ + N+ SS S
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSD-----SNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 1046 KDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKP 1105
+ + ++S + + ++ E D S S+ + + + N
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 1106 --LDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEK 1163
D+ + + D SS + + ++ S ++ D +
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 1164 DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTG 1223
D S + + + S + SN+ + S +S+ S + G
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS--DSSDG 850
Query: 1224 TEGSSSTLVDYTSTS-STGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQV 1282
++ SS D +++S S+ S S + +D+ + E N+ +++ + +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS----DSNESSNSSDSSDSSN------- 899
Query: 1283 PQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKF 1342
S D D + + S+ S S + S+ SN + +
Sbjct: 900 -SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 1343 TKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNE 1402
+ D S+ + SS +S SS + D S ++ + +S + + D N
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 1403 QGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTR 1462
+ S S SS + +SD DS+ +S + D + + D D+ + S S + ++ +
Sbjct: 1019 SDSSNS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077
Query: 1463 RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNE 1522
DS + S S + + D +S S D + D+ ++
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Query: 1523 ETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKP 1582
+ S D + + ++ ++ +SS + + + + D S
Sbjct: 1138 SSNSSDSSDSSESS----DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193
Query: 1583 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1642
S SS SSD + +D + D ++S S+ S + S N S D D + +S
Sbjct: 1194 DSSDSSD-SSDSSDSSDSS----DSSDSSDSSDSSDSSDSSDSNESSDSSD-----SSDS 1243
Query: 1643 LDTAAVVQVGISRNQSHS-SPSVSPSRSHSPSGSQTRSHSSSASSAESQDS 1692
D++ S + S S S S S S S SG+ + S S S +E DS
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDS 1294
Score = 100 bits (249), Expect = 1e-20
Identities = 171/880 (19%), Positives = 313/880 (35%), Gaps = 83/880 (9%)
Query: 842 TRGRREDYVGGQSHRSRNIGSN-----YPEKLSARDGHNQKDNTKSKEKESENAPGDGKG 896
++G+ G + +IG N Y + D HN+ D K+ + E EN+ G +
Sbjct: 277 SKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSE-ENSAGIPED 335
Query: 897 NKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEP 956
N ++ +K E K E +E++T + V S+D ++
Sbjct: 336 NGSQRIEDTQKLNHRES-----------KRVENRITKESETHA--VGKSQDKGIEIKGPS 382
Query: 957 MDAESITFKSVSEKDKRERDKP-----------KAKGDKTKRKNDGSAVSKKENIVKPAK 1005
+IT K V + ++ + DK K +G+ + G +
Sbjct: 383 SGNRNIT-KEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNT 441
Query: 1006 GPQEKVDGER-----ERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSK 1060
G DG ++S + + P + +E+ D+ S S + + + SK
Sbjct: 442 GSDSNSDGYDSYDFDDKSMQGDDP--NSSDESNGNDDANSESDNNSSSRGDASYNSDESK 499
Query: 1061 SAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEK 1120
++K +++ D S T + N N D K + K K++
Sbjct: 500 DNGNGSDSKGAEDD--------DSDSTSDTNNSDSNGNGNNGNDDND-KSDSGKGKSDSS 550
Query: 1121 GVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRE 1180
D D SS + ++ + D+ D + D S + +
Sbjct: 551 --DSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 1181 TGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSST 1240
+ + S++K S K ES SS K ++ +SS D + +S +
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDS---------KSDSSDSNSSDSSDNSDSSDS 659
Query: 1241 GGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVK 1300
S + + + N+ +++ + D S D +S + D
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS------SNSSESSDSSDSSDSDSS 713
Query: 1301 STQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKN 1360
+ S+ S N S + +S S + SS +
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 1361 SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSD 1420
S SS+ + D + S ++ + +S + D + + S SS + +SD
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD--SSDSSDSDSSNSSDSSNSSD 831
Query: 1421 KHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNK 1480
DS+ +S + D + + D +D D+ S S + ++ + +S + S S + +
Sbjct: 832 SSDSSNSSDSSDSSDSSDG-SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 1481 PREERDLPKKGTGDSK-KSNSSPSRDRKPHDHKA----TYDTKRPNEETKSVDKNPCKDR 1535
+ D DS SNSS S D + + D ++ + S D + D
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD- 949
Query: 1536 EKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLS--SD 1593
+ ++ N+ +SS + N ++ + + D S S SS S SD
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSS-DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 1594 LTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI 1653
+ +D + N SDS SN S + S + S D D + +S D++
Sbjct: 1009 SSDSSDSSNSSDSSNSSDS-SNSSDSSDSSDSSDSSDSSD-----SSDSSDSSNSSDSSD 1062
Query: 1654 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSAS-SAESQDS 1692
S + S SS S S S S S S SS++S S++S DS
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Score = 74.7 bits (182), Expect = 7e-13
Identities = 109/696 (15%), Positives = 232/696 (33%), Gaps = 23/696 (3%)
Query: 862 SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLE 921
SN + + D + D++ S + +S+++ + + S+ N + +
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 922 TSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAK 981
+S S + +DS S D + S + +S D + D
Sbjct: 659 SSNSSNSSDS--SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS---- 712
Query: 982 GDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSS 1041
D + N S+ S N + + S S + + + +D++ SS
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS-SDSSDSSNSSDSSDSS 771
Query: 1042 SSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNE 1101
SS + + S S+ + ++ + D S S + +
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSS-DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 1102 KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTP 1161
+ N + G D D + S + + ++ S ++ + +
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 1162 EKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKV 1221
D S + + + N S++ E S ++++S
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950
Query: 1222 TGTEGSS-----STLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDV 1276
+ + SS S D + ++S+ S S + +D+ + + + ++ N++ + D
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSNSSDSSDS 1009
Query: 1277 IIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS 1336
S + +S S SS +S + S ++ +S S
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069
Query: 1337 EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESN 1396
+ SS +S SS+ + D S ++ + +S + +
Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Query: 1397 LDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDE 1456
D + + S S SS + +SD DS+ +S + D + + D D+ S S +
Sbjct: 1130 SDSSDSSDSSNS-SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Query: 1457 KNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRD-RKPHDHKATY 1515
++ + DS + S S + + D S S+SS S D + D +
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-------SSDSSDSSDSSDSNESSDSSDSS 1241
Query: 1516 DTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGN 1551
D+ + + S D + D + +++ SGN
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Score = 73.6 bits (179), Expect = 2e-12
Identities = 101/680 (14%), Positives = 215/680 (31%), Gaps = 26/680 (3%)
Query: 848 DYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRK 907
D S + + S+ + + + N D++ S + ++ D +
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 908 GEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSV 967
+ S S + + + +DS S D + S + S
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS---NSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 968 SEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKK 1027
D + D + + + + ++ + S S+
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813
Query: 1028 AKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSE 1087
++ ++++ SS+SS + + S S+ + + S D
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 1088 KLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPK 1147
++ + NE + D+ ++ +SS S + +E S
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS-DSSESSNSSDN 932
Query: 1148 RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSK 1207
+ D + D + S + + + S N S++ + S +S+ S
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNS---SDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 1208 VKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNN 1267
+ + + SS + S+ S+ S S + +D+ + ++
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS-------DSSDS 1042
Query: 1268 DNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVK 1327
+++ + D S D +S + S SS +S N S +
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 1328 YPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKN 1387
+S S + + SS +S SS + D S ++ + +
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162
Query: 1388 STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTRE 1447
S + + D ++ N S SS + +SD DS+ +S + D + + D D+ +
Sbjct: 1163 SDSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221
Query: 1448 YSSSKRRDEKNELTRRKDS-----------PSRNKDSASGQKNKPREERDLPKKGTGDSK 1496
S S + NE + DS S + DS+ + E K G G++
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281
Query: 1497 KSNSSPSRDRKPHDHKATYD 1516
S+S + +H + D
Sbjct: 1282 GSDSDSDSEGSDSNHSTSDD 1301
Score = 65.9 bits (159), Expect = 3e-10
Identities = 115/572 (20%), Positives = 210/572 (36%), Gaps = 63/572 (11%)
Query: 1158 DRTPEKDKISLSAPAKKIKLNRETGKKIG----STENISNTKEPSEKLESTSSKVKQE-- 1211
D+ + + + + + + +E G ++ ST+N E S + E +S++ +
Sbjct: 159 DKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQIN 218
Query: 1212 -KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNT 1270
K G +VT G + L + + S G+ + E D + ++ +N++
Sbjct: 219 SKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSK 278
Query: 1271 APAEDVIIMIQVPQSKWDKDDFES---EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVK 1327
Q Q +DD +S + D K P + + T S
Sbjct: 279 G---------QEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENS 329
Query: 1328 YPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKN 1387
E S++I+ K E + E + +K S + GK++D+ + K +N
Sbjct: 330 AGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEI--KGPSSGNRN 387
Query: 1388 STQPEKESNLDR--------------LNEQGNFKSLSQSSKEARTSDK--HDSTRASSNK 1431
T+ + N + + QG ++ +++ +K H +T + SN
Sbjct: 388 ITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNS 447
Query: 1432 DFTPNRDKKTDYDTREYSS-SKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKK 1490
D YD+ ++ S + D+ N D + N D+ S N D
Sbjct: 448 D---------GYDSYDFDDKSMQGDDPNS----SDESNGNDDANSESDNNSSSRGDASYN 494
Query: 1491 GTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSG 1550
N S S+ + D +T DT + + N D+ ++ +S
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554
Query: 1551 NKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETD--EAAFEPDYN 1608
+ + ++ + S S SSD + +D +++ D +
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 1609 E----SDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSV 1664
+ SDS+S+ S E +SS + SK D + +S D + S N S SS S
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSK--SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 1665 SPSRSHSPSGSQTRSHSS----SASSAESQDS 1692
S S S S S S SS S++S+ES DS
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Score = 54.3 bits (129), Expect = 1e-06
Identities = 98/481 (20%), Positives = 163/481 (33%), Gaps = 80/481 (16%)
Query: 1331 KESEPSEKIQKFTKDVSHEIIQHEVKSSKNSA------SSEKGKTKDRDYSV-------L 1377
+E P + D EII++ ++ N++ +S++ TK+ + + L
Sbjct: 180 QEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGL 239
Query: 1378 EKENPEKRKNSTQPEKE--SNLDRLNEQGNFKSLSQSSK--EARTSDKHDSTRASSNKDF 1433
+ + N +++ S D E GN K S +SK E + K D +S +
Sbjct: 240 DNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQ-- 297
Query: 1434 TPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG 1493
N D K YD + D NE+ K S S + + N + D K
Sbjct: 298 --NSDSKEYYDPEG-----KEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHR 350
Query: 1494 DSKKSNSSPSRDRKPHDHKATYDT----KRPNEETKSVDKNPCKDREKHVLEARNNKESS 1549
+SK+ + +++ + H + D K P+ +++ K K E KE
Sbjct: 351 ESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNE--------GKEDK 402
Query: 1550 GNKLLYI-LNPPETQVEKEQITGQIDKSTVKPKPQLSHSSR------------------- 1589
G + + +TQ E I G KS +P ++ HS+
Sbjct: 403 GQHGMILGKGNVKTQGEVVNIEGPGQKS--EPGNKVGHSNTGSDSNSDGYDSYDFDDKSM 460
Query: 1590 -----LSSDLTRETDEAAFEPDYNES---DSESNVSVKEEESSGNISKDLKDKIVEKAKE 1641
SSD + D+A E D N S D+ N ++ +G+ SK +D + +
Sbjct: 461 QGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520
Query: 1642 S------------LDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAES 1689
+ D G ++ S S S S S S S S S SS++S
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS 580
Query: 1690 QDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
S + + + S K SK D K
Sbjct: 581 DSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640
Query: 1750 D 1750
D
Sbjct: 641 D 641
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 114 bits (285), Expect = 8e-25
Identities = 327/1471 (22%), Positives = 506/1471 (34%), Gaps = 246/1471 (16%)
Query: 481 HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE 540
H + P + R G P E S P+ + S Y ++ +
Sbjct: 287 HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKS 346
Query: 541 RSQRTQGPSLPATPVFVPVPPPPLY------PPPPHTLPLP--PGVPPPQFSP---QFPP 589
++ + P +T P P P L P P T PL P PP + SP + PP
Sbjct: 347 ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPP 406
Query: 590 GQP---PPAGYSVPPPGFP-----------------PAPANLSTPWVSSGVQT------- 622
P P + S P P PAPA S +SS +
Sbjct: 407 KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGR 466
Query: 623 -----AHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSY-----SRSSYTYSKSR 672
+HS+T S R + R + +K +S S SRS+ + +SR
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR 526
Query: 673 SGSTRSRSYS----------------RSFSRSHSRSYSRSPPYPRRGRGKS--RNYRSRS 714
S R RS S RS S RS+SRSP R R ++ R RSRS
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586
Query: 715 RSHGYHRSRSRSP---------PYRRYHSRSRSP--QAFRGQSPNKRNVPQGETEREYFN 763
R+ RSRSR+P P RR SRSR+P + R +SP +R R
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGR 646
Query: 764 RYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANR 823
P A GRS R P + R R R + + A + R R
Sbjct: 647 SRSRTP------ARRGRSRS-RTPARRGRSRSRTPARRSGRSR-SRTPARRGRSRSRTPR 698
Query: 824 ENFSPERFLPLNIRN---SPFTRGR------REDYVGGQSHRSRNIGSNYPEK--LSARD 872
S R L R+ +P RGR R++ RSR+ S +K +S+R
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758
Query: 873 GH---NQKDNTKSKEKESENAPGDGKGNKHKKH---RKRRKGEESEGFLNPELLETSRKS 926
+ + KS+ + G K K R+ R G + SR S
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818
Query: 927 REPTGVEENKT------DSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDK---RERDK 977
P +++KT S P TP R + + +SV+ + +
Sbjct: 819 SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878
Query: 978 PKAKGDKTKRKN-DGSAVSKKENIVKP------AKGPQEKVDG-----ERERSPRSEP-P 1024
P+ K R + GS+ + ++ P + PQ KV +R S S P P
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938
Query: 1025 IKKAKEETPKTDNTKS---------------SSSSQKDEKI--TGTPRKAHSKSAKEHQE 1067
+ TP+ + S S SS D K+ PR++HS S + +
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPK 998
Query: 1068 TK--------------PVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKN----KPLDNK 1109
K P +EK K + K+ P ++ L K
Sbjct: 999 VKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLK 1058
Query: 1110 GEKR-----KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTP-EK 1163
G+ + + T V + S SK + + K R P TE R+P +
Sbjct: 1059 GQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSP--KGGRSRSSSPVTELASRSPIRQ 1116
Query: 1164 DKISLSA-PAKKIKLNRETGKKIGSTENI----SNTKEPSEKLESTSSKVKQEKVKGKVR 1218
D+ SA P K ++ E + + + SN+ +LE+ SK
Sbjct: 1117 DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESK----------- 1165
Query: 1219 RKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVII 1278
K+ +T PV+ E + + ++T + + E
Sbjct: 1166 EKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ 1225
Query: 1279 MIQVPQSKWDKDDFESEEEDVKSTQPISSV-GKPASVIKNVSTKPSNIVKYPEKESEPSE 1337
+P S D++ E E KS +P + +S +K +ST SN PE E P+
Sbjct: 1226 NSALPTSSQDEELMEVVE---KSEEPAGQILSHLSSELKEMST--SNFESSPEVEERPAV 1280
Query: 1338 KIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLE----KEN----PEKRKNST 1389
+ T D S E + ASS G ++ L +EN P + +NS
Sbjct: 1281 SL---TLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG 1337
Query: 1390 QPEKESNL---DRLNEQGNFKSLSQSSKEARTSDKHDSTRAS--SNKDFTPNRDKKTDYD 1444
E N + E N L+Q + K STR+S S+ + +P+ +K
Sbjct: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMS 1397
Query: 1445 TREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSR 1504
+ + SS D +PSR + S++ + P + LP+ + S+ +S R
Sbjct: 1398 SNQSISSPVLDAVPR------TPSRERSSSA---SSPEMKDGLPRTPSRRSRSGSSPGLR 1448
Query: 1505 DRK--PHDHKATYDT-------KRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLY 1555
D P H + + + P+ D +P R+ SS
Sbjct: 1449 DGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNK 1508
Query: 1556 ILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESN 1615
L P Q E+ +D+ TV P L SR S + +A + +ESDS +
Sbjct: 1509 CLTP---QRERSGSESSVDQKTVARTP-LGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564
Query: 1616 VSVK-------EEESSGNISKDLKDKIVEKAKESLDTAAVVQV--GISRNQSHS------ 1660
K S + D K ++ + S + V R QS S
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
Query: 1661 ---SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHA 1717
+P P RS S S S+ R S SS+ + K + ++ + K K
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684
Query: 1718 GTEVELEKSQKHKHKKKK-SKKNKDKEKEKE 1747
+S +K + S++++ E
Sbjct: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
Score = 93.6 bits (231), Expect = 2e-18
Identities = 361/1798 (20%), Positives = 620/1798 (34%), Gaps = 280/1798 (15%)
Query: 114 LTKTANLAEANASEEDKIKAMMSQS-----GHEYDP---INYMKKPLGPPPPSYTCFRCG 165
+T+T LAE N + ++++A S G +DP K+P PP Y+ R
Sbjct: 118 VTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRES 177
Query: 166 KPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDA 225
K + G R +S+ R K + + K+ PT +
Sbjct: 178 SSSRSPTPKQKKKKKKKDRGRR-SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKS 236
Query: 226 EAYAIGKKEK------PPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSY 279
+ + KK K P S+ D + + G S
Sbjct: 237 KRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSP 296
Query: 280 CDECIRTALLESD---EHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQL 336
R E D T Q SP+ +Q + ++++ K
Sbjct: 297 SPASGRRG--EGDAPFSEPGTTSTQRPSSPETAT-----KQPSSPYEDKDKDKKEKSATR 349
Query: 337 PPPPP------PIPP-PRPLIQR----NLQPLMRSPISRQ-----------------QDP 368
P P P P PP P PL+ + QPL +P+S++ + P
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 369 LMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDG- 427
+P +SSS PS ++ + + P S P+ AP +I+ S +S G
Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS---SSPTSKNRSHGR 466
Query: 428 PFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHG----- 482
RD + P+ + S T+ + TP+ G S
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR-----------TPTKRGHSRSRSPQWRR 515
Query: 483 -----QLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRH 537
+ + P R +R RPGW S RRG RS RGR
Sbjct: 516 SRSAQRWGRSRSPQRRGRSR-SPQRPGWSRSRNTQ---------RRGRS---RSARRGRS 562
Query: 538 HSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGY 597
HS RS T+G S T P P P + S P + +
Sbjct: 563 HS-RSPATRGRSRSRT----PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617
Query: 598 SVPP--PGFPPAPANLSTPWVSSGVQTAHSNT-IPTTQAPPLSREEFYREQRRLKEESKS 654
P +P + S ++ S + P + SR R + R + ++
Sbjct: 618 RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR 677
Query: 655 PYSGSSYSRSSYTYSKSRSGS-TRSRSYSRSFSRSHSRSYSRSPPYPRRGR--------G 705
SG S SR+ +SRS + R RS SRS R RS+SR+P RRGR
Sbjct: 678 --SGRSRSRTPARRGRSRSRTPRRGRSRSRSLVR-RGRSHSRTP--QRRGRSGSSSERKN 732
Query: 706 KSRNYRSRSRSH----------GYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQG 755
KSR + RSRS+ RSRS S P + SR ++ G SP + Q
Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792
Query: 756 ETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGA 815
R +R P + RS P K++ + R+ + K +G
Sbjct: 793 PPRR---SRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK-VKSGT 848
Query: 816 QPR------PSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLS 869
PR P AN ++ +P+R P + R R GS+ P
Sbjct: 849 PPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS-------RHSCSGSSPP---- 897
Query: 870 ARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKR-RKGEESEGFLNPELLETSRKSRE 928
K +T ++ S ++ K R+R G S T R+SR
Sbjct: 898 -----RVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 929 P---TGVEENKTDSLFVLPSRDDATPVRDE--PMDAESITFKSVSEKDKRERDKPKAKGD 983
+ VE S T V+ E P + S + + + P G
Sbjct: 953 VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGS 1012
Query: 984 KTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSE----------------PPIKK 1027
K+ + S K+++V+ G G + +P E P +
Sbjct: 1013 KSPCPQEKS----KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
Query: 1028 AKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAK---EHQETKPVKEEKVKKDYSKDV 1084
+ +P+ + S S S + + T +P+ S+S+ E P+++++ + S +
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQT-SPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML 1127
Query: 1085 KSEKLTTKEEKAKKPNEKNKPLDNK---GEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1141
KS ++ ++ + + + +D+ G+ R E K M + E
Sbjct: 1128 KS-GMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESK--------EKMALPPQEDATA 1178
Query: 1142 VKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKL 1201
P K K P P +D+ S K R ++ + TKE + L
Sbjct: 1179 SPPRQKDKFSP-------FPVQDRPESSLVFKDTL--RTPPRERSGAGSSPETKEQNSAL 1229
Query: 1202 ESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKT 1261
++S + +V K S+ + STS+ SP + + + V T
Sbjct: 1230 PTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP------EVEERPAVSLT 1283
Query: 1262 MEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPI--SSVGKPASVIKN-- 1317
+++ + + A +V M S W F E +++ S P+ +S G P +
Sbjct: 1284 LDQSQSQASLEAVEVPSM----ASSWGGPHFSPEHKEL-SNSPLRENSFGSPLEFRNSGP 1338
Query: 1318 VSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS-------SEKGKTK 1370
+ T+ + KE + + D S ++ + +SS +S+S + G +
Sbjct: 1339 LGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSS 1398
Query: 1371 DRDYS------VLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDS 1424
++ S V + E+ +++ PE + L R + + S ++ + S
Sbjct: 1399 NQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHS 1458
Query: 1425 TRASS--NKDF--TPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNK 1480
SS KD TP+R + + E + + +R SP N + Q+ +
Sbjct: 1459 LSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR--SRSPSSPELNNKCLTPQRER 1516
Query: 1481 PREERDLPKKGT-----GDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDR 1535
E + +K G +S SS D KP + P E ++S K +
Sbjct: 1517 SGSESSVDQKTVARTPLGQRSRSGSSQELDVKP--------SASPQERSESDSSPDSKAK 1568
Query: 1536 EKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS----TVKPKPQLSHSSRLS 1591
+ L R+ SS PE K +++ + +S VK KP+ + ++
Sbjct: 1569 TRTPLRQRSRSGSS----------PEVD-SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSG 1617
Query: 1592 SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEK-------AKESLD 1644
SD + E A S S S+ + G+ S + + K ++ S +
Sbjct: 1618 SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677
Query: 1645 TAAVVQVGISRNQSHSSPSVS-----PSRSHSPSGS-QTRS-----HSSSASSAESQDSK 1693
+ R S SSP ++ RS S S S +TRS H S S + + ++
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
Query: 1694 KKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
K + + ++ + ++ + Q+ + + ++ K + +++ Q
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ 1795
Score = 93.2 bits (230), Expect = 2e-18
Identities = 273/1342 (20%), Positives = 474/1342 (35%), Gaps = 251/1342 (18%)
Query: 632 QAPPLSREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRS------GSTRSRSYSRSF 685
Q P SR QRR + S+S G S+SRS T +SRS G +RSR+ +R
Sbjct: 538 QRPGWSRSR--NTQRRGR--SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRR 593
Query: 686 SRSHS----RSYSRSPPYPRRGRGKSRN---YRSRSRSHGYHRSRSRSPPYRRYHSRSRS 738
SRS + RS SR+P RRGR +SR RSR+RS RSRSRSP R SRSR+
Sbjct: 594 SRSRTPTRRRSRSRTPA--RRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
Query: 739 PQAFRGQS----PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYR 794
P A RG+S P +R + T R R P A GRS + R R
Sbjct: 652 P-ARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP-----ARRGRSRSRTPRRGRSRSR 705
Query: 795 EWERKYREWYEK-YYKGYAAGAQPRPSANR-------ENFSPE----RFLPLNIRNSPFT 842
R+ R +G + + R + +R N SPE R R+
Sbjct: 706 SLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765
Query: 843 RGRREDYVG------GQS-----------HRSRNIGSNYPEKLSARDGHNQKDNTKSKEK 885
R + + + G S RSR+ GS+ P+ S + ++ K
Sbjct: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRS-GSSQPKAKSRTPPRRSRSSSSPPPK 824
Query: 886 ESENAPGDGKGNKHKKHRKRRKG-----------EESEGFLNPELLETSRKSREP---TG 931
+ P + H K + G + +E + P+ S +P +
Sbjct: 825 QKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSR 884
Query: 932 VEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERD-------KPKAKGDK 984
+ S P +TP R P + S K + R+R P +
Sbjct: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944
Query: 985 T--KRKNDGSAVSKKENIVKP------AKGPQEKVDGE---RERSPRSEPPIKKAKEETP 1033
T +R S S E+ + P + P KV E R+ S P K K +TP
Sbjct: 945 TTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP 1004
Query: 1034 KTDNTKSSSSSQKDEK-------------------------------ITGTPRKAHSKSA 1062
+ S S EK ++ K S+++
Sbjct: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064
Query: 1063 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTE---- 1118
+H+ E + S ++S+ T+ + + + L ++ R+ + E
Sbjct: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
Query: 1119 ---EKGVDKD---FESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPA 1172
+ G+ + F+S S ++ ++ S E EKM P++D + S P
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAE-SKEKMALPPQEDATA-SPPR 1182
Query: 1173 KKIKLN------------------RETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVK 1214
+K K + R ++ + TKE + L ++S + +V
Sbjct: 1183 QKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVV 1242
Query: 1215 GKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAE 1274
K S+ + STS+ SP + + + V T+++ + + A
Sbjct: 1243 EKSEEPAGQILSHLSSELKEMSTSNFESSP------EVEERPAVSLTLDQSQSQASLEAV 1296
Query: 1275 DVIIMIQVPQSKWDKDDFESEEEDVKSTQPI--SSVGKPASVIKN------VSTKPSNIV 1326
+V M S W F E +++ S P+ +S G P + ++T S+ V
Sbjct: 1297 EVPSMA----SSWGGPHFSPEHKEL-SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEV 1351
Query: 1327 KYP-------EKESEPSEKIQK--------FTKDVSHEIIQHEVKSSKNSASSE------ 1365
K + E++PS +++ + ++S + ++ SS S SS
Sbjct: 1352 KEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP 1411
Query: 1366 KGKTKDRDYSVLEKE-----------------NPEKRKNSTQPEKES---------NLDR 1399
+ +++R S E +P R S P + S ++ R
Sbjct: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
Query: 1400 LNEQGNFKSLSQSSKEA-----RTSDKHDSTRASSNKDFTPNRDK-------------KT 1441
+G + S +A R + S+ +NK TP R++ +T
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
Query: 1442 DYDTREYS-SSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNS 1500
R S SS+ D K + ++ S S + + + P +R KS
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 1501 SPSRDR---------KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARN---NKES 1548
SP R R KP + E K+ R + ++ + E
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 1549 SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN 1608
S + +PP+++ + + T P SSR S +LTR+ + +
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
Query: 1609 ES-DSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPS 1667
S ++ S + S S + +K + ++ + R +S S
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771
Query: 1668 RSHSPS-GSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS 1726
RS S S +TR+ S SQ + +++++ + ++ H+ + E S
Sbjct: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
Query: 1727 QKHKHKKKKSKKNKDKEKEKEK 1748
+ +++ + +++ +
Sbjct: 1832 RTSSRRRRGRSRTPPTSRKRSR 1853
Score = 72.0 bits (175), Expect = 5e-12
Identities = 171/842 (20%), Positives = 308/842 (36%), Gaps = 93/842 (11%)
Query: 916 NPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFK-SVSEKDKRE 974
NP++L+ RK R E L + ++ + + TF+ + EKD
Sbjct: 54 NPDILDHERKRRVELRCLE--------LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNP 105
Query: 975 RDKPKAKGDK---TKRKNDGSAVSKKENIVKPAKGPQEK-VDGERERSPRSEPPIKKAKE 1030
K + G + T+ KK ++ A G + VDG R K+
Sbjct: 106 GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP 165
Query: 1031 ETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEH---QETKPVKEEKVKKDYSKDVKSE 1087
E PK + SSS + TP++ K K+ E+ + E+ K K +SE
Sbjct: 166 EPPKPYSLVRESSSSRSP----TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221
Query: 1088 KLTTKEE-KAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSP 1146
+ K + ++ P K K D K ++ + T + S+S + T +
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS 281
Query: 1147 KRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSS 1206
T R+P +PA R G S ++T+ PS +T
Sbjct: 282 AAAKTHTTALAGRSP--------SPASG---RRGEGDAPFSEPGTTSTQRPSSPETATKQ 330
Query: 1207 KVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
+ K K +++ + T S S + +ST +P E+ + T
Sbjct: 331 PSSPYEDKDKDKKEKSATRPSPSP--ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQ 388
Query: 1267 NDNTAPAEDVIIMIQVPQSKWDK-DDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNI 1325
P+E + P +K S E S QP + V + AS S KP+
Sbjct: 389 EPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP-TKVSRHASSSPE-SPKPAPA 446
Query: 1326 V-KYPEKESEPSEKIQ---KFTKDVSH-EIIQHEVKSSKNSASSEKGKTKDRDYSVL--- 1377
+ E S P+ K + + +D SH + S++ A++++G+++ R +
Sbjct: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
Query: 1378 -----------------EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSD 1420
+P++R S P++ N Q + S+S++ R+
Sbjct: 507 RSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR--RGRSRSARRGRSHS 564
Query: 1421 KHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD---SPSRNKDSAS-- 1475
+ +TR S + TP R + +R + ++RR TRR+ +P+R S S
Sbjct: 565 RSPATRGRS-RSRTPARRGR----SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619
Query: 1476 GQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK-- 1533
+ + R + ++ S S SR R P + ++ P +S + P +
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP-ARRGRSRSRTPARRGRSRSRTPARRS 678
Query: 1534 DREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSD 1593
R + AR + S P + + + +S + PQ S SS+
Sbjct: 679 GRSRSRTPARRGRSRS--------RTPRRGRSRSRSLVRRGRSHSR-TPQRRGRSGSSSE 729
Query: 1594 LTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD-KIVEKAKESLDTAAVVQVG 1652
++ S S S+ +K+ S S+ L + K++ SL +
Sbjct: 730 RKNKS-----RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 1653 ISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKK 1712
+ +S + P S S S P +++R+ + S+ S K+K K ++ H H K
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPK-AKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843
Query: 1713 HK 1714
K
Sbjct: 844 VK 845
Score = 68.6 bits (166), Expect = 5e-11
Identities = 277/1427 (19%), Positives = 473/1427 (33%), Gaps = 165/1427 (11%)
Query: 358 MRSPISRQQDPLMIPVTSSSTHPAPSISSLT--------SNQ---SSLAPPVSGNPSSAP 406
+ SP S+ + L + + S + P P S T S+Q S PP SS+P
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP 821
Query: 407 APVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQV 466
P + T S HS S P S + + + ++ + + + E
Sbjct: 822 PPKQK-SKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Query: 467 PVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGER 526
TPS S + ++ P R + +R +P K+ ++SP Q+ G
Sbjct: 881 LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP------KVKAIISPRQRSHSGSS 934
Query: 527 SCYRSINRGRHHSERSQRTQ----------------GPSLPATPVFVPVPPPPLYPPPPH 570
S S R RS+ G S P T V PP H
Sbjct: 935 SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQ-----SH 989
Query: 571 TLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPT 630
+ + P P+ Q PPG S P P S + + S
Sbjct: 990 SGSISPY---PKVKAQTPPGPSLSGSKS-------PCPQEKSKDSLVQSCPGSLSLCAGV 1039
Query: 631 TQAPPLSREEFYREQRRLKEESK-SPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSH 689
+ P F +LK +S+ SP S S S S S S +S+S + S
Sbjct: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT---SPKG 1096
Query: 690 SRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNK 749
RS S SP R R R + +S SP R+ S S S S
Sbjct: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKS-GMSPEQSRFQSDSSSYPTVDSNSL-- 1153
Query: 750 RNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYK 809
+ Q E +PP D A R D PF + E +++ +
Sbjct: 1154 --LGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPR 1211
Query: 810 GYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRG-RREDYVGGQ--SHRSRNIG----S 862
+GA P +N + LP + ++ + + GQ SH S + S
Sbjct: 1212 E-RSGAGSSPETKEQNSA----LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTS 1266
Query: 863 NYPEKLSARDGH------NQKDNTKSKEKESENAPGDGKGNKH--KKHRKRRKGEESEGF 914
N+ + +Q + S E + G H +H++ E
Sbjct: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENS 1326
Query: 915 LNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRE 974
L ++ P G E N S V ++D + P + T S+ K++
Sbjct: 1327 FGSPL---EFRNSGPLGTEMNTGFSSEV---KEDL----NGPFLNQLETDPSLDMKEQST 1376
Query: 975 RDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPK 1034
R + + + + + +S ++I P + S S P +K TP
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Query: 1035 TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLT-TKE 1093
+ SS +D +GTP + + + P + + + + + L T
Sbjct: 1437 RRSRSGSSPGLRDG--SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494
Query: 1094 EKAKKPNEKNKPLDNK--GEKRKRKTEEKGVDKDF--------ESSSMKISKLEVTEIVK 1143
+++ P+ L+NK +R+R E VD+ S S +L+V
Sbjct: 1495 PRSRSPSSPE--LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552
Query: 1144 PSPKRKME--PDTEKMDRTPEKDKI-SLSAPA--KKIKLNRETGKKIGSTENISNTKEPS 1198
P + + + PD++ RTP + + S S+P K +L+ + GS+ + + +
Sbjct: 1553 PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS-GSSPEVKDKPRAA 1611
Query: 1199 EKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEE---KTDTK 1255
+ +S S + K GSSS S G S S E K+ T
Sbjct: 1612 PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK---GRGPSPEGSSSTESSPEHPPKSRTA 1668
Query: 1256 RTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVI 1315
R ++ E + P P+ + + E + S + S+ P
Sbjct: 1669 RRGSRSSPEPKTKSRTP----------PRRRSSRSSPELTRKARLSRRSRSASSSP---- 1714
Query: 1316 KNVSTKPSNIVKYPEKES-EPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEK--GKTKDR 1372
+ S P + P S EP+EK + + S + + S + + S K G + R
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774
Query: 1373 DYSVLEKENPEKRKN--------STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDS 1424
S EK +R++ S + ++ + R+ + S S AR S
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Query: 1425 TRASSNKDFTPNRDKKTDYDTREYSSSKR-RDEKNELTRRKD----------------SP 1467
+R + TP +K + KR R + T R+ SP
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP 1894
Query: 1468 SRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSV 1527
+ S S R R + +S + P R+ T +R T V
Sbjct: 1895 VSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPT-TRRRSRSRTPPV 1953
Query: 1528 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1587
+ + R V R+ +S + ++ +T + +S P +
Sbjct: 1954 TRRRSRSRTPPVTRRRSRSRTSP------ITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007
Query: 1588 SRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAA 1647
SR +S +TR + P + + S ++ + + +
Sbjct: 2008 SR-TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKR 2066
Query: 1648 VVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKK 1694
+ + S+ S RS S + TR+HS S + + +S +
Sbjct: 2067 SLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSR 2113
Score = 52.8 bits (125), Expect = 3e-06
Identities = 50/150 (33%), Positives = 66/150 (44%), Gaps = 12/150 (8%)
Query: 644 EQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSR-------- 695
+++R S S S SS S SS + S S S S+ S S S S S S S S ++
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 696 --SPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNK--RN 751
SP P G +SR+ R S RS S SP RR S SP+ + S + R
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
Query: 752 VPQGETEREYFNRYREVPPPYDMKAYYGRS 781
+G++ R RE P P M+ RS
Sbjct: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 45.8 bits (107), Expect = 4e-04
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Query: 1604 EPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRN-QSHSSP 1662
E D N E + + + +L +K E+ + + + G S + Q +
Sbjct: 100 EKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRARE 159
Query: 1663 SVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVE 1722
+ P+ S R SSS S Q KKKKKKK++ + + ++ +K + + +
Sbjct: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQ--KKKKKKKDRGRRSESSSPRRERKKSSKKKK 217
Query: 1723 LEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1757
+ K +K +S K K K K+K ++ +S T
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT 252
Score = 43.1 bits (100), Expect = 0.002
Identities = 62/339 (18%), Positives = 110/339 (32%), Gaps = 30/339 (8%)
Query: 909 EESEGFLNPELLETSRKSREPTGVEENKTDS---------LFVLPSRDDATPVRDEPMDA 959
E G +P LL+ +R P+ +++ S + PS+ P +D+P
Sbjct: 2391 ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP 2450
Query: 960 ESITFKSVSEKDKRERDKPKAKGDKTKR----KNDGSAVSKKENIVKPAKGPQEKVDGER 1015
F S + + P A SA + PA G GE
Sbjct: 2451 VPSAFSDQS-RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
Query: 1016 ERSPRSEPP-----IKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKP 1070
S ++ P ++ AKE + ++ SSSSS + + + S S+ + P
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 1071 VKEEKVKKDYSKDVKSEKLTTKEEKAKKP-----------NEKNKPLDNKGEKRKRKTEE 1119
V+ E K + K +E + +P + + + +
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 1120 KGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNR 1179
SSS S KP P+ +P + K E+ S P ++ +R
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Query: 1180 ETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVR 1218
S P ++ S+S + + +G R
Sbjct: 2690 SLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR 2728
Score = 39.3 bits (90), Expect = 0.034
Identities = 101/414 (24%), Positives = 137/414 (33%), Gaps = 51/414 (12%)
Query: 336 LPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTH---PAPSISSLTSNQS 392
L P P+ + R PL+ +R + P P S T P+PS +
Sbjct: 2380 LTSPRVPLSAYERVSGRTSPPLLDR--ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437
Query: 393 SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSS 452
SL PP P S PVP S S++S + L A S+ SS
Sbjct: 2438 SLLPPAQDQPRS---PVP--------SAFSDQS---------RCLIAQTTPVAGSQSLSS 2477
Query: 453 IAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTG---PVRINTARPGGGRPGWEHSN 509
A+ G +L P+ G+ +TG P + +P R S+
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
Query: 510 KLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATP--VFVPVPPPPLYPP 567
S S S + G S+ ++G SLP P VP P P
Sbjct: 2538 ------SSSSSSSSSSSSSSSSSSSGSSSSD----SEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 568 PPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNT 627
PP P + + + S + ++ S+ SS ++ S++
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 628 IPTTQAPPLSREEFYREQRRLKEES-KSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFS 686
P+ P Q K S K P G SRS S S RS SYS
Sbjct: 2648 SPSPAKPG--------PQALPKPASPKKPPPGERRSRSPRKPIDSLRDS-RSLSYSPVER 2698
Query: 687 RSHSRSYS-RSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSP 739
R S S R RG R R SRS + R R P H SRSP
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 32.0 bits (71), Expect = 5.5
Identities = 47/240 (19%), Positives = 86/240 (35%), Gaps = 28/240 (11%)
Query: 1518 KRPN-----EETKSVDKNPCKDREKHVLEARNNKESSGNKL----LYILNPPETQVEKEQ 1568
KRPN E K + C + E+ + E ++ K+ L +L KE+
Sbjct: 51 KRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEE 110
Query: 1569 ITGQIDKSTVKPKPQLSHSSRLSSDLTRET--------DEAAFEPDYNESDSESNVSVKE 1620
GQ + V QL+ + ++ R D ++F+P +++
Sbjct: 111 TPGQ--RPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPP 168
Query: 1621 E------ESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG 1674
+ ESS + S K K K K+ D + R + S RS S S
Sbjct: 169 KPYSLVRESSSSRSPTPKQK---KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225
Query: 1675 SQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKK 1734
+ + S +S+D K+K+ + K + H+ + + + +S+ K
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 109 bits (273), Expect = 2e-23
Identities = 189/865 (21%), Positives = 349/865 (40%), Gaps = 109/865 (12%)
Query: 946 RDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAK 1005
R TP+R P + +T S E ++ ++K K K+ S+ S +N KP K
Sbjct: 620 RVKTTPLR-RPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDN-PKPNK 677
Query: 1006 GPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEH 1065
P+ K +++ S+ + KE + + S SS D I + H+ +
Sbjct: 678 LPKSKQSETVDQNSDSDEMLAILKEVS------RMSHSSSSDTDIN----EIHTNHKTLY 727
Query: 1066 Q-ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDK 1124
+T+ K++K K+ TK+ K+ K + +K +KR+ ++E D
Sbjct: 728 DLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK------KKRQTQSESSNYDS 781
Query: 1125 DFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK 1184
+ E +SK+ K K P+T+ D + E +K S + N +T ++
Sbjct: 782 ELEKEIKSMSKIGAARTTK-----KRIPNTKDFDSS-EDEKHSKKGMDNQGHKNLKTSQE 835
Query: 1185 IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTL--VDYTS--TSST 1240
GS+++ + K+ E S V ++ ++R ++ + +S++ VD S S
Sbjct: 836 -GSSDD-AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSF 893
Query: 1241 GGSPVRK-SEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV 1299
VRK +E K +K KT ++ + + AE + K D+ D SE++
Sbjct: 894 TSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL--------KKDQSDETSEDDKK 945
Query: 1300 KSTQPISSVGKPASVIKNV-------STKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQ 1352
+S + KP+ K V + K PE+E K K + +
Sbjct: 946 QSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH--FPKGIKQIKNGTTD 1003
Query: 1353 HEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK-NSTQPEKESNLDRLNEQGNFKSLSQ 1411
E KS K + K K + DY+ EK + +S++ +K N E+ K L +
Sbjct: 1004 GEKKSKKIRDKTSKKKDELSDYA--EKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1061
Query: 1412 SSKEARTSDKHDSTRASSNKDFTPNRDKKT---DYDTREYSSSKRRDEKNELTRRKDSPS 1468
SS++ + D+ + S +D + DK+ + R SSKR T+ S S
Sbjct: 1062 SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN------TKEIQSGS 1115
Query: 1469 RNKDSA-SGQKNKPREERDLPKKGT---GDSKKSNSSPSRDRKPHDHKATYDTKRPNEET 1524
+ D+ S + NK +++R KK + K+++ S RK D ++ + +++
Sbjct: 1116 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1175
Query: 1525 KSVDKNPCKDR------EKHVLEARNNK-ESSGNKLLYIL-----------NPPETQVEK 1566
S+ + ++ E VL + +SSG++ L N PE ++ K
Sbjct: 1176 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1235
Query: 1567 EQITGQI-------DKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVK 1619
+ + +I + + +P+ + DE A +ESDS+S S K
Sbjct: 1236 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1295
Query: 1620 EEE-----------SSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSR 1668
S G ++ K K E + V S + VS
Sbjct: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1355
Query: 1669 SHSPSGSQTRSHSSS-ASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQ 1727
S S + R+ S+ A E+Q S K+KKK+ + K ++ + E+ +
Sbjct: 1356 SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS-------EEEE 1408
Query: 1728 KHKHKKKKSKKNKDKEKEKEKDDQK 1752
+ K ++++ ++ +++E+E E DD K
Sbjct: 1409 EEKEEEEEEEEEEEEEEEDENDDSK 1433
Score = 93.2 bits (230), Expect = 2e-18
Identities = 177/925 (19%), Positives = 362/925 (39%), Gaps = 57/925 (6%)
Query: 867 KLSAR--DGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 924
KLS + D + N ++E+ + + G +K + + + L+ +++ S
Sbjct: 425 KLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIV--SV 482
Query: 925 KSREPTGVEENKTDSLFVLPSRD---DATPVRDEPMDAESITFKSVSEKDKRERDKPKAK 981
S P + EN ++ V S D D + ++ +++ S+ ++S KD R K K
Sbjct: 483 PSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKL-NISSKDNRGGIKSKTT 541
Query: 982 GDKTKRKNDG-SAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDN--- 1037
TK + VS + +K A + D + +S P ++K +DN
Sbjct: 542 AKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHL 601
Query: 1038 TKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
++ S +E + + + ET PV ++ + +KL+ K
Sbjct: 602 VENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKD 661
Query: 1098 KPNEKNKPLDN-KGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEK 1156
K N + +DN K K + + + VD++ +S M EV+ + S + D +
Sbjct: 662 KRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRM---SHSSSSDTDINE 718
Query: 1157 MDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGK 1216
+ T K L A K + K S + K S K S K +Q + +
Sbjct: 719 I-HTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESS 777
Query: 1217 VRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDV 1276
E S + + T+ P K + ++ ++ K M+ + N +++
Sbjct: 778 NYDSELEKEIKSMSKIGAARTTKKR-IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEG 836
Query: 1277 IIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE-SEP 1335
+ K +++ F S E V I + + S + K KE S
Sbjct: 837 --SSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFT 894
Query: 1336 SEKIQKF--TKDVSHEIIQHEVKSSKNSAS--SEKGKTKDRDYSVLEKENPEKRKNSTQP 1391
S +++K TK+ S + K ++ S +EK KD+ E + + +K + +
Sbjct: 895 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEK 954
Query: 1392 EKESNLDR--LNEQGNFKSLSQSSKEARTSDK--HDSTRASSNKDFTPNRDKKTDYDTRE 1447
+K S+ + + + ++S S +++ ++ H K+ T + +KK+ R+
Sbjct: 955 KKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSK-KIRD 1013
Query: 1448 YSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKP----REERDLPKKGTGDSKKSNSSPS 1503
+SK++DE ++ + + DS+ +K+K RE++ G K+ + S S
Sbjct: 1014 -KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS 1072
Query: 1504 RDRKPHDHKATYDTKRP--NEETKSVDKNPCKDREKHVLEARNNKE-SSGNKLLYILNPP 1560
K Y K N K + + ++R +++ RN KE SG+
Sbjct: 1073 DTEK-------YSMKEDGCNSSDKRLKRIELRER-RNLSSKRNTKEIQSGSSSSDAEESS 1124
Query: 1561 ETQVEKEQITGQIDKST-VKPKPQLS---HSSRLSSDLTRETDEAAFEPDYNESDSESNV 1616
E +K+Q T K+ VK K + S + R +D+T + + D N S+
Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
Query: 1617 SVKEEESSGNISKDLKDKIVEKA-KESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGS 1675
K + + N+ + + E+L + V V + + ++ +
Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1244
Query: 1676 QTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKK 1735
S +S E ++ KK+ K+ ++ + + + ++ E K +++H+ +
Sbjct: 1245 NLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR 1304
Query: 1736 SK------KNKDKEKEKEKDDQKVK 1754
K ++ +++K K K+ ++VK
Sbjct: 1305 HKLTVSDGESGEEKKTKPKEHKEVK 1329
Score = 83.6 bits (205), Expect = 2e-15
Identities = 147/743 (19%), Positives = 266/743 (35%), Gaps = 97/743 (13%)
Query: 864 YPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETS 923
Y K A K KS S+ GK K K+++ +SE LE
Sbjct: 727 YDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKE 786
Query: 924 RKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGD 983
KS G + P+ D DE + + ++ K + + D
Sbjct: 787 IKSMSKIGAARTTKKRI---PNTKDFDSSEDEKHSKKGMD----NQGHKNLKTSQEGSSD 839
Query: 984 KTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSS 1043
+RK + S E V E R+R P+ + + + K + S +
Sbjct: 840 DAERKQERETFSSAEGTVDKDTTIMEL----RDRLPKKQQA-SASTDGVDKLSGKEQSFT 894
Query: 1044 SQKDEKITGTPRKAH---SKSAKEHQE-TKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKP 1099
S + K+ T K+ +K+ K+ Q+ + E+ +KKD S + + K++ K
Sbjct: 895 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD---KKQSKKGT 951
Query: 1100 NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDR 1159
EK KP D K + K +++ +ESSS KL E + PK + D
Sbjct: 952 EEKKKPSDFKKKVIK-------MEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDG 1004
Query: 1160 TPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRR 1219
+ KI KK +L+ K G ++ ++++ K + + K+ K+ GK R
Sbjct: 1005 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSR 1064
Query: 1220 KVTGTEGSSSTLVDYT---------------------------------------STSST 1240
K + SSS Y+ S +
Sbjct: 1065 K--RQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEE 1122
Query: 1241 GGSPVRKSEEKTDTKRTVIKTMEEYNND-NTAPAEDVIIMIQVPQSKWDKDDFESEEEDV 1299
+K +++T +K+ + E+ N T+ + S + DD S E
Sbjct: 1123 SSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGS 1182
Query: 1300 KSTQPISSVGK-----------PASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSH 1348
Q I V + +S + +S V + +++P +I K +
Sbjct: 1183 SDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRI---AKKMLL 1239
Query: 1349 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENP--EKRKNSTQPEKESNLD-------- 1398
E I+ + S ++ +S ++ + + +ENP E+ KN E +S+ +
Sbjct: 1240 EEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYR 1299
Query: 1399 -RLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEK 1457
RL S +S +E +T K N+ + D + D D +E S+ E
Sbjct: 1300 HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE-DSDFQESGVSEEVSES 1358
Query: 1458 NELTRRKDSPSRNKDSASGQ---KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKAT 1514
+ R + ++ + Q K K + R ++ + KSNS + K + +
Sbjct: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Query: 1515 YDTKRPNEETKSVDKNPCKDREK 1537
+ + E+ K+P K R+K
Sbjct: 1419 EEEEEEEEDENDDSKSPGKGRKK 1441
Score = 73.6 bits (179), Expect = 2e-12
Identities = 170/933 (18%), Positives = 346/933 (37%), Gaps = 162/933 (17%)
Query: 964 FKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR--- 1020
F+++ + ++ + K K +K+ + + ++ + G ++K+D S
Sbjct: 246 FENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSY 305
Query: 1021 -----SEPPIKKAKEETPKTDNTKSS-----SSSQKDEKITGTPRKAHSKSAKEHQETKP 1070
+ IKKAK+ T N SS + + +I+ + K+ K
Sbjct: 306 SALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIK 365
Query: 1071 VKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGV--DKDFES 1128
+++D + + ++ KE+ K+ +K +D K E + RK E+ KD
Sbjct: 366 KAHLALEEDLNSEFRAMDAVNKEKNTKE----HKVIDAKFETKARKGEKPCALEKKDISK 421
Query: 1129 SSMKISKLEV----------TEIVKPSPK---------RKMEPDTEKMDRTPEKDKISLS 1169
S K+S+ +V TE + + RK EP E + + + D +S
Sbjct: 422 SEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVS 481
Query: 1170 APA---KKIKLNRETGKKIGST-----ENISNTKEPSEKLE---STSSKVKQEKVKGKVR 1218
P+ + I N ET ++ S+ + S T++ E + SSK + +K K
Sbjct: 482 VPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTT 541
Query: 1219 RKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKT------MEEYNNDNTAP 1272
KVT T V +++ G ++K K + + + N+DN
Sbjct: 542 AKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHL 601
Query: 1273 AEDVIIMIQVPQSKWDKDDFESEEEDVK-----STQPISSVGKPASVIKNVSTKPSNIVK 1327
E+ + ++ EE D++ T P+ + V N + + VK
Sbjct: 602 VENEVSLLL-------------EESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVK 648
Query: 1328 YPEKESEPSEKIQKFTKDVSHEIIQH----EVKSSKNSASSEKGKTKDRDYSVLEKENPE 1383
+K S P K K ++ S I + ++ SK S + ++ D ++L++ +
Sbjct: 649 EKQKLSVPVRKKDK--RNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVS-- 704
Query: 1384 KRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK--- 1440
+ +S+ + + N N + + +Q+ K+ + K S+ + S+ D + K
Sbjct: 705 RMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSI 764
Query: 1441 -------TDYDTREYSSSKRRDEKN-------ELTRRK-------DSPSRNKDSASGQKN 1479
T ++ Y S ++ K+ T+++ DS K S G N
Sbjct: 765 ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 824
Query: 1480 KPREERDLPKKGTGDS------------------KKSNSSPSRDRKPHDHKATYDTKRPN 1521
+ + ++G+ D K + RDR P +A+ T +
Sbjct: 825 QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 884
Query: 1522 E-----------ETKSVDKNPCKDREKHVLEARNNKESSG-----NKLLYILNPPETQ-- 1563
+ E + V + K++ KH+ K G K L ET
Sbjct: 885 KLSGKEQSFTSLEVRKVAET--KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSED 942
Query: 1564 --------VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESN 1615
E+++ K +K + Q SS + L + F + + +
Sbjct: 943 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT 1002
Query: 1616 VSVKEEESSGNISKDLKDKIVEKAKESL---DTAAVVQVGISRNQSHSSPSV-------S 1665
K+ + + + KD++ + A++S D+ + S+N ++ S
Sbjct: 1003 DGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS 1062
Query: 1666 PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEK 1725
+ S S T +S S D + K+ + ++++ K++ K + + + E+
Sbjct: 1063 SRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEE 1122
Query: 1726 SQK-HKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1757
S + +K KK+++ K KEK +++ T
Sbjct: 1123 SSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1155
Score = 56.2 bits (134), Expect = 3e-07
Identities = 62/311 (19%), Positives = 123/311 (39%), Gaps = 16/311 (5%)
Query: 853 QSHRSRNIGSNYPEKLSARDGHNQKDNTKSKE------KESENAPGDGKGNKHKKHRKRR 906
QS + + P + D N +N +K+ K + ++ DG + + K+R
Sbjct: 1205 QSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKR 1264
Query: 907 KGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESIT--- 963
G+++E E + S + EE+K R T V D E T
Sbjct: 1265 TGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT-VSDGESGEEKKTKPK 1323
Query: 964 -FKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVD-GERERSPRS 1021
K V +++R+ ++ + VS+ E+ +P +K + E +RS +
Sbjct: 1324 EHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQ 1383
Query: 1022 EPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYS 1081
+ ++ K + + KS+S +++EK + + +E + K +K
Sbjct: 1384 KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR 1443
Query: 1082 KDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1141
K +K +KL T+ + A K E+ + + E+ + K E +D + I+ T++
Sbjct: 1444 KILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPIT----TKL 1499
Query: 1142 VKPSPKRKMEP 1152
V + EP
Sbjct: 1500 VLDEDEETKEP 1510
Score = 55.8 bits (133), Expect = 4e-07
Identities = 116/641 (18%), Positives = 238/641 (37%), Gaps = 108/641 (16%)
Query: 868 LSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSR 927
L R K+ +K + ++ DG + +K K+ + +E+ + + + + +
Sbjct: 896 LEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKK 955
Query: 928 EPTGVE----------ENKTDSLFVLPSRDDAT-------PVRDEPMDAESITFKSVSEK 970
+P+ + E+ +D LP R++ +++ D E + K + +K
Sbjct: 956 KPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKS-KKIRDK 1014
Query: 971 DKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE 1030
+++D+ +K+ K D S+ + A G ++K +S R +
Sbjct: 1015 TSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDT 1074
Query: 1031 E--TPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEK 1088
E + K D SS K ++ + ++ KE Q + + + +K K ++
Sbjct: 1075 EKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNK--KKKQ 1132
Query: 1089 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
T+ ++KA EK + KRK+ D E + E S ++
Sbjct: 1133 RTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQN----SIGE--GSSDEQ 1186
Query: 1149 KMEPDTEKM--------DRTPEKDKISLSAP----------------AKKIKLNRETGKK 1184
K++P TE + ++ + +S S P AKK+ L E
Sbjct: 1187 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLL-EEIKAN 1245
Query: 1185 IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSS----------TLVDY 1234
+ S E+ S+ EP E + T + ++ + + +V S S L+ +
Sbjct: 1246 LSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1305
Query: 1235 TSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFES 1294
T S G S K + + K + + +++++ ++ +S ++ ES
Sbjct: 1306 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD-------FQESGVSEEVSES 1358
Query: 1295 EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHE 1354
E+E +P + K A + +N + Y +K+ K+Q E
Sbjct: 1359 EDEQ----RPRTRSAKKAELEENQRS-------YKQKKKRRRIKVQ-------------E 1394
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
SS+N ++SE E E+++ + E+E + +E + KS + K
Sbjct: 1395 DSSSENKSNSE--------------EEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
Query: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRD 1455
+ R K D R + +++ RE K R+
Sbjct: 1441 KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1481
Score = 34.3 bits (77), Expect = 1.1
Identities = 23/115 (20%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1370 KDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASS 1429
K D+ E E+ + + N D+++ G+ + ++SKE TS S + S
Sbjct: 17 KLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGS 76
Query: 1430 NKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREE 1484
+R K+ +Y S ++ T +D+ + N ++ ++ P+E+
Sbjct: 77 ------SRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKED 125
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 109 bits (273), Expect = 2e-23
Identities = 189/865 (21%), Positives = 349/865 (40%), Gaps = 109/865 (12%)
Query: 946 RDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAK 1005
R TP+R P + +T S E ++ ++K K K+ S+ S +N KP K
Sbjct: 658 RVKTTPLR-RPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDN-PKPNK 715
Query: 1006 GPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEH 1065
P+ K +++ S+ + KE + + S SS D I + H+ +
Sbjct: 716 LPKSKQSETVDQNSDSDEMLAILKEVS------RMSHSSSSDTDIN----EIHTNHKTLY 765
Query: 1066 Q-ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDK 1124
+T+ K++K K+ TK+ K+ K + +K +KR+ ++E D
Sbjct: 766 DLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK------KKRQTQSESSNYDS 819
Query: 1125 DFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK 1184
+ E +SK+ K K P+T+ D + E +K S + N +T ++
Sbjct: 820 ELEKEIKSMSKIGAARTTK-----KRIPNTKDFDSS-EDEKHSKKGMDNQGHKNLKTSQE 873
Query: 1185 IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTL--VDYTS--TSST 1240
GS+++ + K+ E S V ++ ++R ++ + +S++ VD S S
Sbjct: 874 -GSSDD-AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSF 931
Query: 1241 GGSPVRK-SEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV 1299
VRK +E K +K KT ++ + + AE + K D+ D SE++
Sbjct: 932 TSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL--------KKDQSDETSEDDKK 983
Query: 1300 KSTQPISSVGKPASVIKNV-------STKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQ 1352
+S + KP+ K V + K PE+E K K + +
Sbjct: 984 QSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH--FPKGIKQIKNGTTD 1041
Query: 1353 HEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK-NSTQPEKESNLDRLNEQGNFKSLSQ 1411
E KS K + K K + DY+ EK + +S++ +K N E+ K L +
Sbjct: 1042 GEKKSKKIRDKTSKKKDELSDYA--EKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1099
Query: 1412 SSKEARTSDKHDSTRASSNKDFTPNRDKKT---DYDTREYSSSKRRDEKNELTRRKDSPS 1468
SS++ + D+ + S +D + DK+ + R SSKR T+ S S
Sbjct: 1100 SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN------TKEIQSGS 1153
Query: 1469 RNKDSA-SGQKNKPREERDLPKKGT---GDSKKSNSSPSRDRKPHDHKATYDTKRPNEET 1524
+ D+ S + NK +++R KK + K+++ S RK D ++ + +++
Sbjct: 1154 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1213
Query: 1525 KSVDKNPCKDR------EKHVLEARNNK-ESSGNKLLYIL-----------NPPETQVEK 1566
S+ + ++ E VL + +SSG++ L N PE ++ K
Sbjct: 1214 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1273
Query: 1567 EQITGQI-------DKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVK 1619
+ + +I + + +P+ + DE A +ESDS+S S K
Sbjct: 1274 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1333
Query: 1620 EEE-----------SSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSR 1668
S G ++ K K E + V S + VS
Sbjct: 1334 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1393
Query: 1669 SHSPSGSQTRSHSSS-ASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQ 1727
S S + R+ S+ A E+Q S K+KKK+ + K ++ + E+ +
Sbjct: 1394 SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS-------EEEE 1446
Query: 1728 KHKHKKKKSKKNKDKEKEKEKDDQK 1752
+ K ++++ ++ +++E+E E DD K
Sbjct: 1447 EEKEEEEEEEEEEEEEEEDENDDSK 1471
Score = 93.2 bits (230), Expect = 2e-18
Identities = 177/925 (19%), Positives = 362/925 (39%), Gaps = 57/925 (6%)
Query: 867 KLSAR--DGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 924
KLS + D + N ++E+ + + G +K + + + L+ +++ S
Sbjct: 463 KLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIV--SV 520
Query: 925 KSREPTGVEENKTDSLFVLPSRD---DATPVRDEPMDAESITFKSVSEKDKRERDKPKAK 981
S P + EN ++ V S D D + ++ +++ S+ ++S KD R K K
Sbjct: 521 PSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKL-NISSKDNRGGIKSKTT 579
Query: 982 GDKTKRKNDG-SAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDN--- 1037
TK + VS + +K A + D + +S P ++K +DN
Sbjct: 580 AKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHL 639
Query: 1038 TKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
++ S +E + + + ET PV ++ + +KL+ K
Sbjct: 640 VENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKD 699
Query: 1098 KPNEKNKPLDN-KGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEK 1156
K N + +DN K K + + + VD++ +S M EV+ + S + D +
Sbjct: 700 KRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRM---SHSSSSDTDINE 756
Query: 1157 MDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGK 1216
+ T K L A K + K S + K S K S K +Q + +
Sbjct: 757 I-HTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESS 815
Query: 1217 VRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDV 1276
E S + + T+ P K + ++ ++ K M+ + N +++
Sbjct: 816 NYDSELEKEIKSMSKIGAARTTKKR-IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEG 874
Query: 1277 IIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE-SEP 1335
+ K +++ F S E V I + + S + K KE S
Sbjct: 875 --SSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFT 932
Query: 1336 SEKIQKF--TKDVSHEIIQHEVKSSKNSAS--SEKGKTKDRDYSVLEKENPEKRKNSTQP 1391
S +++K TK+ S + K ++ S +EK KD+ E + + +K + +
Sbjct: 933 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEK 992
Query: 1392 EKESNLDR--LNEQGNFKSLSQSSKEARTSDK--HDSTRASSNKDFTPNRDKKTDYDTRE 1447
+K S+ + + + ++S S +++ ++ H K+ T + +KK+ R+
Sbjct: 993 KKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSK-KIRD 1051
Query: 1448 YSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKP----REERDLPKKGTGDSKKSNSSPS 1503
+SK++DE ++ + + DS+ +K+K RE++ G K+ + S S
Sbjct: 1052 -KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS 1110
Query: 1504 RDRKPHDHKATYDTKRP--NEETKSVDKNPCKDREKHVLEARNNKE-SSGNKLLYILNPP 1560
K Y K N K + + ++R +++ RN KE SG+
Sbjct: 1111 DTEK-------YSMKEDGCNSSDKRLKRIELRER-RNLSSKRNTKEIQSGSSSSDAEESS 1162
Query: 1561 ETQVEKEQITGQIDKST-VKPKPQLS---HSSRLSSDLTRETDEAAFEPDYNESDSESNV 1616
E +K+Q T K+ VK K + S + R +D+T + + D N S+
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222
Query: 1617 SVKEEESSGNISKDLKDKIVEKA-KESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGS 1675
K + + N+ + + E+L + V V + + ++ +
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1282
Query: 1676 QTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKK 1735
S +S E ++ KK+ K+ ++ + + + ++ E K +++H+ +
Sbjct: 1283 NLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR 1342
Query: 1736 SK------KNKDKEKEKEKDDQKVK 1754
K ++ +++K K K+ ++VK
Sbjct: 1343 HKLTVSDGESGEEKKTKPKEHKEVK 1367
Score = 83.6 bits (205), Expect = 2e-15
Identities = 147/743 (19%), Positives = 266/743 (35%), Gaps = 97/743 (13%)
Query: 864 YPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETS 923
Y K A K KS S+ GK K K+++ +SE LE
Sbjct: 765 YDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKE 824
Query: 924 RKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGD 983
KS G + P+ D DE + + ++ K + + D
Sbjct: 825 IKSMSKIGAARTTKKRI---PNTKDFDSSEDEKHSKKGMD----NQGHKNLKTSQEGSSD 877
Query: 984 KTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSS 1043
+RK + S E V E R+R P+ + + + K + S +
Sbjct: 878 DAERKQERETFSSAEGTVDKDTTIMEL----RDRLPKKQQA-SASTDGVDKLSGKEQSFT 932
Query: 1044 SQKDEKITGTPRKAH---SKSAKEHQE-TKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKP 1099
S + K+ T K+ +K+ K+ Q+ + E+ +KKD S + + K++ K
Sbjct: 933 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD---KKQSKKGT 989
Query: 1100 NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDR 1159
EK KP D K + K +++ +ESSS KL E + PK + D
Sbjct: 990 EEKKKPSDFKKKVIK-------MEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDG 1042
Query: 1160 TPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRR 1219
+ KI KK +L+ K G ++ ++++ K + + K+ K+ GK R
Sbjct: 1043 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSR 1102
Query: 1220 KVTGTEGSSSTLVDYT---------------------------------------STSST 1240
K + SSS Y+ S +
Sbjct: 1103 K--RQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEE 1160
Query: 1241 GGSPVRKSEEKTDTKRTVIKTMEEYNND-NTAPAEDVIIMIQVPQSKWDKDDFESEEEDV 1299
+K +++T +K+ + E+ N T+ + S + DD S E
Sbjct: 1161 SSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGS 1220
Query: 1300 KSTQPISSVGK-----------PASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSH 1348
Q I V + +S + +S V + +++P +I K +
Sbjct: 1221 SDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRI---AKKMLL 1277
Query: 1349 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENP--EKRKNSTQPEKESNLD-------- 1398
E I+ + S ++ +S ++ + + +ENP E+ KN E +S+ +
Sbjct: 1278 EEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYR 1337
Query: 1399 -RLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEK 1457
RL S +S +E +T K N+ + D + D D +E S+ E
Sbjct: 1338 HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE-DSDFQESGVSEEVSES 1396
Query: 1458 NELTRRKDSPSRNKDSASGQ---KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKAT 1514
+ R + ++ + Q K K + R ++ + KSNS + K + +
Sbjct: 1397 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1456
Query: 1515 YDTKRPNEETKSVDKNPCKDREK 1537
+ + E+ K+P K R+K
Sbjct: 1457 EEEEEEEEDENDDSKSPGKGRKK 1479
Score = 73.6 bits (179), Expect = 2e-12
Identities = 170/933 (18%), Positives = 346/933 (37%), Gaps = 162/933 (17%)
Query: 964 FKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR--- 1020
F+++ + ++ + K K +K+ + + ++ + G ++K+D S
Sbjct: 284 FENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSY 343
Query: 1021 -----SEPPIKKAKEETPKTDNTKSS-----SSSQKDEKITGTPRKAHSKSAKEHQETKP 1070
+ IKKAK+ T N SS + + +I+ + K+ K
Sbjct: 344 SALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIK 403
Query: 1071 VKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGV--DKDFES 1128
+++D + + ++ KE+ K+ +K +D K E + RK E+ KD
Sbjct: 404 KAHLALEEDLNSEFRAMDAVNKEKNTKE----HKVIDAKFETKARKGEKPCALEKKDISK 459
Query: 1129 SSMKISKLEV----------TEIVKPSPK---------RKMEPDTEKMDRTPEKDKISLS 1169
S K+S+ +V TE + + RK EP E + + + D +S
Sbjct: 460 SEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVS 519
Query: 1170 APA---KKIKLNRETGKKIGST-----ENISNTKEPSEKLE---STSSKVKQEKVKGKVR 1218
P+ + I N ET ++ S+ + S T++ E + SSK + +K K
Sbjct: 520 VPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTT 579
Query: 1219 RKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKT------MEEYNNDNTAP 1272
KVT T V +++ G ++K K + + + N+DN
Sbjct: 580 AKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHL 639
Query: 1273 AEDVIIMIQVPQSKWDKDDFESEEEDVK-----STQPISSVGKPASVIKNVSTKPSNIVK 1327
E+ + ++ EE D++ T P+ + V N + + VK
Sbjct: 640 VENEVSLLL-------------EESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVK 686
Query: 1328 YPEKESEPSEKIQKFTKDVSHEIIQH----EVKSSKNSASSEKGKTKDRDYSVLEKENPE 1383
+K S P K K ++ S I + ++ SK S + ++ D ++L++ +
Sbjct: 687 EKQKLSVPVRKKDK--RNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVS-- 742
Query: 1384 KRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK--- 1440
+ +S+ + + N N + + +Q+ K+ + K S+ + S+ D + K
Sbjct: 743 RMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSI 802
Query: 1441 -------TDYDTREYSSSKRRDEKN-------ELTRRK-------DSPSRNKDSASGQKN 1479
T ++ Y S ++ K+ T+++ DS K S G N
Sbjct: 803 ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 862
Query: 1480 KPREERDLPKKGTGDS------------------KKSNSSPSRDRKPHDHKATYDTKRPN 1521
+ + ++G+ D K + RDR P +A+ T +
Sbjct: 863 QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 922
Query: 1522 E-----------ETKSVDKNPCKDREKHVLEARNNKESSG-----NKLLYILNPPETQ-- 1563
+ E + V + K++ KH+ K G K L ET
Sbjct: 923 KLSGKEQSFTSLEVRKVAET--KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSED 980
Query: 1564 --------VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESN 1615
E+++ K +K + Q SS + L + F + + +
Sbjct: 981 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT 1040
Query: 1616 VSVKEEESSGNISKDLKDKIVEKAKESL---DTAAVVQVGISRNQSHSSPSV-------S 1665
K+ + + + KD++ + A++S D+ + S+N ++ S
Sbjct: 1041 DGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS 1100
Query: 1666 PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEK 1725
+ S S T +S S D + K+ + ++++ K++ K + + + E+
Sbjct: 1101 SRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEE 1160
Query: 1726 SQK-HKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1757
S + +K KK+++ K KEK +++ T
Sbjct: 1161 SSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1193
Score = 56.2 bits (134), Expect = 3e-07
Identities = 62/311 (19%), Positives = 123/311 (39%), Gaps = 16/311 (5%)
Query: 853 QSHRSRNIGSNYPEKLSARDGHNQKDNTKSKE------KESENAPGDGKGNKHKKHRKRR 906
QS + + P + D N +N +K+ K + ++ DG + + K+R
Sbjct: 1243 QSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKR 1302
Query: 907 KGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESIT--- 963
G+++E E + S + EE+K R T V D E T
Sbjct: 1303 TGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT-VSDGESGEEKKTKPK 1361
Query: 964 -FKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVD-GERERSPRS 1021
K V +++R+ ++ + VS+ E+ +P +K + E +RS +
Sbjct: 1362 EHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQ 1421
Query: 1022 EPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYS 1081
+ ++ K + + KS+S +++EK + + +E + K +K
Sbjct: 1422 KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR 1481
Query: 1082 KDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1141
K +K +KL T+ + A K E+ + + E+ + K E +D + I+ T++
Sbjct: 1482 KILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPIT----TKL 1537
Query: 1142 VKPSPKRKMEP 1152
V + EP
Sbjct: 1538 VLDEDEETKEP 1548
Score = 55.8 bits (133), Expect = 4e-07
Identities = 116/641 (18%), Positives = 238/641 (37%), Gaps = 108/641 (16%)
Query: 868 LSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSR 927
L R K+ +K + ++ DG + +K K+ + +E+ + + + + +
Sbjct: 934 LEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKK 993
Query: 928 EPTGVE----------ENKTDSLFVLPSRDDAT-------PVRDEPMDAESITFKSVSEK 970
+P+ + E+ +D LP R++ +++ D E + K + +K
Sbjct: 994 KPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKS-KKIRDK 1052
Query: 971 DKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE 1030
+++D+ +K+ K D S+ + A G ++K +S R +
Sbjct: 1053 TSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDT 1112
Query: 1031 E--TPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEK 1088
E + K D SS K ++ + ++ KE Q + + + +K K ++
Sbjct: 1113 EKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNK--KKKQ 1170
Query: 1089 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
T+ ++KA EK + KRK+ D E + E S ++
Sbjct: 1171 RTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQN----SIGE--GSSDEQ 1224
Query: 1149 KMEPDTEKM--------DRTPEKDKISLSAP----------------AKKIKLNRETGKK 1184
K++P TE + ++ + +S S P AKK+ L E
Sbjct: 1225 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLL-EEIKAN 1283
Query: 1185 IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSS----------TLVDY 1234
+ S E+ S+ EP E + T + ++ + + +V S S L+ +
Sbjct: 1284 LSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1343
Query: 1235 TSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFES 1294
T S G S K + + K + + +++++ ++ +S ++ ES
Sbjct: 1344 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD-------FQESGVSEEVSES 1396
Query: 1295 EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHE 1354
E+E +P + K A + +N + Y +K+ K+Q E
Sbjct: 1397 EDEQ----RPRTRSAKKAELEENQRS-------YKQKKKRRRIKVQ-------------E 1432
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
SS+N ++SE E E+++ + E+E + +E + KS + K
Sbjct: 1433 DSSSENKSNSE--------------EEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1478
Query: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRD 1455
+ R K D R + +++ RE K R+
Sbjct: 1479 KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1519
Score = 32.3 bits (72), Expect = 4.2
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1450 SSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPH 1509
SS+ +E + R + + +K S SG + E ++GT S+KS SS S K
Sbjct: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSK--EEGTSSSEKSKSSGSSRSK-- 80
Query: 1510 DHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQI 1569
++P+ TK V+ + K + + + E+S N + P T + + +
Sbjct: 81 --------RKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEP 132
Query: 1570 TGQIDKSTVKPKPQLSHSSRLSSDLTRETDE 1600
DK K P+ S++ ++ ++ E
Sbjct: 133 VLNEDKDDFK-GPEFRSRSKMKTENLKKRGE 162
Score = 31.6 bits (70), Expect = 7.1
Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 1370 KDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASS 1429
K D+ E E+ + + N D+++ G+ + ++SKE TS S + S
Sbjct: 17 KLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGS 76
Query: 1430 NKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPR 1482
+R K+ +Y S ++ T +D+ + N ++ ++ P+
Sbjct: 77 ------SRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPK 123
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 108 bits (269), Expect = 6e-23
Identities = 226/1167 (19%), Positives = 439/1167 (37%), Gaps = 213/1167 (18%)
Query: 645 QRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRS-----PPY 699
+R++ E+ S S+ R S S + + + R++ ++ + Y + P
Sbjct: 5 RRKVTVENTKTISDSTSRRPSVFERLGPSTGSTAETQCRNWLKTGNCLYGNTCRFVHGPS 64
Query: 700 PRRGRGKSRNYR-SRSRSHGYHRSRSRSP-------PYRRYHSRSRSP---QAFRGQSPN 748
PR G+G S NYR S R G R R ++ P +R S SP ++ RG+
Sbjct: 65 PR-GKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHRE 123
Query: 749 KRNV-------PQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYR 801
K ++ P+ E E + R+ D+ Y + +K + RE + +
Sbjct: 124 KEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQ-RELMKLEQ 182
Query: 802 EWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIG 861
E EK + + P R SP ++R S + R+
Sbjct: 183 ENMEKREE-IIIKKEVSPEVVRSKLSPSP----SLRKSSKSPKRKSS------------- 224
Query: 862 SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNP--EL 919
P+ SA + K ++ + ++P + K ++ ++KG + P E
Sbjct: 225 ---PKSSSA--------SKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPED 273
Query: 920 LETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPK 979
+ +K +E V++ + +RD RD E+ + +RDKP+
Sbjct: 274 IALGKKYKEKYKVKDRIEEK-----TRDGKDRGRD-------------FERQREKRDKPR 315
Query: 980 AKGDKTKR------KNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETP 1033
+ + ++ S+ +I + + P+ K PP++++ P
Sbjct: 316 STSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYP 375
Query: 1034 K---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEE-KVKKDYSKDVKSEKL 1089
+ + S + + R H ++++ H +E+ + K+D KD + E+
Sbjct: 376 SHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREERE 435
Query: 1090 TTKEEKAKKPNEKNK-PLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
+++ + + + ++ P D + + R T ++ +D S M+ S+ R
Sbjct: 436 YEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRD--SRDMRDSR----------EMR 483
Query: 1149 KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGS-------------TENISNTK 1195
DT K R P + + A + + R+T +K + E S T+
Sbjct: 484 DYSRDT-KESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTE 542
Query: 1196 EPSEKLESTSSKVKQEKVKGKVRRKVT-----GTEGSSSTLVDYTSTSSTGGSPVRKSEE 1250
+E + S+++ +++ G+ R +V G+ GS + +D S++S +
Sbjct: 543 IRNESRNESRSEIRNDRM-GRSRGRVPELPEKGSRGSRGSQIDSHSSNSN-------YHD 594
Query: 1251 KTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGK 1310
+T+ + + DN A D + ++D ++ E D + + PI G+
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDS----SFERRHGERDRRDNRERDQRPSSPIRHQGR 650
Query: 1311 PASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTK 1370
E E E+ ++ D V ++ + E+ + +
Sbjct: 651 -------------------NDELERDERREERRVD--------RVDDRRDERARERDRER 683
Query: 1371 DRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDK-HDSTRASS 1429
+RD E+E +R+ + EKE L+R + + + R D+ HD R
Sbjct: 684 ERDR---ERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRER--- 737
Query: 1430 NKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPK 1489
++ +R+K+ + + E + R+ + E R ++ + ++ + E++D
Sbjct: 738 ERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKD--- 794
Query: 1490 KGTGDSKKSNSSPSRDRKPHD-HKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES 1548
KG D ++ DR P D H KR E + K R +H ++
Sbjct: 795 KGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD----- 849
Query: 1549 SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN 1608
N + + EK ++ Q+ V+P+ S S S LT + E D
Sbjct: 850 -------AYNSGDDKNEKHRLLSQV----VRPQESRSLSP---SHLTEDRQGRWKEEDRK 895
Query: 1609 ESDSESNVSVKEEESSGNISKDLKDKI--VEKAKESLDTAAVVQVGISRNQSHSSPSVSP 1666
ES+ +E+E LK+K+ V+K +E + +++ R Q S
Sbjct: 896 PERKESSRRYEEQE--------LKEKVSSVDKQREQTE---ILESSRMRAQDIIGHHQSE 944
Query: 1667 SRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS 1726
R S R+H D KKK K +KK KK K+ + E E
Sbjct: 945 DRETSD-----RAH----------DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDG 989
Query: 1727 QKHKHKKKKSKKNKDKEKEKEKDDQKV 1753
Q KK + KK+ +K+++K K D +
Sbjct: 990 QVFSPKKGQKKKSIEKKRKKSKGDSDI 1016
Score = 104 bits (260), Expect = 7e-22
Identities = 202/1028 (19%), Positives = 369/1028 (35%), Gaps = 128/1028 (12%)
Query: 643 REQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRS-----YSRSFSRSHSRSYSRSP 697
R+ R +ES+ P S +R ++ Y T + SRS+ R+H R S
Sbjct: 483 RDYSRDTKESRDPRDSRS-TRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRT 541
Query: 698 PYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGET 757
R +SR S R+ RSR R P SR S N ET
Sbjct: 542 EIRNESRNESR---SEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWET 598
Query: 758 EREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQP 817
Y R R RD ++ R +ER++ G +
Sbjct: 599 RSSYPERDRYPE---------------RDNRDQARDSSFERRH-------------GERD 630
Query: 818 RPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQK 877
R + P + RN R R + R + E+ RD ++
Sbjct: 631 RRDNRERDQRPSSPIRHQGRNDELERDERRE-----ERRVDRVDDRRDERARERDRERER 685
Query: 878 DNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKT 937
D + +E+E R+R + E E L E + RE E
Sbjct: 686 DRERERERE----------------RERDREREKERELERERAREREREREKERDRERDR 729
Query: 938 DSLFVLPSRD-DATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSK 996
D RD D R+ D E + E+++RER++ + + + +R+ + +
Sbjct: 730 D-------RDHDRERERERERDREK---EREREREERERERERERERERERERERERARE 779
Query: 997 KENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRK 1056
++ K + ++ D ++ R R E + ++ P+ + + S + + + +PR+
Sbjct: 780 RD---KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQ 836
Query: 1057 AHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK 1116
+ K +EH K+ + S+ + +E ++ P+ + + ++ RK
Sbjct: 837 S-PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 895
Query: 1117 TEEKGVDKDFESSSMK--ISKL----EVTEIVKPSPKRKME-------PDTEKMDRTPEK 1163
E K + +E +K +S + E TEI++ S R + D E DR ++
Sbjct: 896 PERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDE 955
Query: 1164 DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTG 1223
+K K IK +E I NI T E + + K +++K K R+K G
Sbjct: 956 NKKKAKIQKKPIKKKKEDDVGI-ERGNIETTSEDGQVF--SPKKGQKKKSIEKKRKKSKG 1012
Query: 1224 TEGSSSTLVDYTSTSSTGGS--PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQ 1281
S S G P+ EE + +E+ + ED
Sbjct: 1013 DSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILED-----SQKKEDTAFSDW 1067
Query: 1282 VPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKN---VSTKPSNIVKYPEKESEPSEK 1338
+ D+ + E +T P S+ +S++ V+T + V + +
Sbjct: 1068 SDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAA 1127
Query: 1339 IQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLD 1398
T ++ ++ N+ ++E K V + E P Q K +
Sbjct: 1128 TSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQK 1187
Query: 1399 RLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSS-----KR 1453
R + G+ +S + S +DS S + R + RE + S +R
Sbjct: 1188 RSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGER 1247
Query: 1454 RDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKA 1513
+ ++L R + S S + D + + R R P+ +S S SRDR +
Sbjct: 1248 KSRIDQLKRGEPSRSTSSDRQDSRSHSSR--RSSPESDRQVHSRSGSFDSRDRLQERDRY 1305
Query: 1514 TYDTKRPNEE--------TKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVE 1565
+D +R E + DK+ ++R++ L R + + + E
Sbjct: 1306 EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKR-------RDLDRE 1358
Query: 1566 KEQ-ITGQIDKSTVKPKPQLSHSSRLSSDLTRETD-EAAFEPDYNESDSESNVSVKEEES 1623
+E+ I+ +++ + + + SS++ S E E E D ES S ++++ +E
Sbjct: 1359 RERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDL-ESTSRDSLALDKE-- 1415
Query: 1624 SGNISKDL 1631
+ KDL
Sbjct: 1416 --RMDKDL 1421
Score = 95.5 bits (236), Expect = 4e-19
Identities = 219/1197 (18%), Positives = 442/1197 (36%), Gaps = 187/1197 (15%)
Query: 628 IPTTQAPPLSREEFYREQRRLKEESKSPYS-GSSYSRSSYTYSKSRSGSTRSRSYSRSFS 686
IP A +E Y+ + R++E+++ G + R K RS S + +S S
Sbjct: 270 IPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISS 329
Query: 687 RSHSRS------YSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRR----YHSRS 736
R HS S R P PRR R S +Y+ R+ +PP RR Y S S
Sbjct: 330 RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQ-----------RTLTPPLRRSASPYPSHS 378
Query: 737 -RSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYRE 795
SPQ R QSP + P E R R + +D + + R D R ++E+
Sbjct: 379 LSSPQ--RKQSPPRHRSPMREKGRHDHERTSQ---SHDRR--HERREDTRGKRDREKDSR 431
Query: 796 WERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRRE--DYVGGQ 853
ER+Y E + + + +PR +R + R +R+S R RE DY
Sbjct: 432 EEREY-EQDQSSSRDHRDDREPRDGRDRRDARDTRDRR-ELRDSRDMRDSREMRDY---- 485
Query: 854 SHRSRNIGSNYPEKLSARDGHNQKDNT-KSKEKESENAPGDGK--GNKHKKHRKRR---- 906
R + + S RD H+ +D + ++ + P + + G H + R
Sbjct: 486 -SRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIR 544
Query: 907 ---KGEESEGFLN----------PELLETSRKSREPTGVEENKTDSLF--------VLPS 945
+ E N PEL E + + ++ + ++S + P
Sbjct: 545 NESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPE 604
Query: 946 RDDATPVRDEPMDAESITFK----SVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIV 1001
RD P RD A +F+ +D RERD+ + + + +ND ++
Sbjct: 605 RD-RYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 1002 KPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKS 1061
+ + + + RER E ++ +E + D + + E+ R+ +
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Query: 1062 AKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKG 1121
+E + E+ +++ +D + E+ +EE+ E+ + + + E+ + + E+
Sbjct: 724 DRERDRDRDHDRER-ERERERDREKEREREREER-----ERERERERERERERERERERA 777
Query: 1122 VDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRET 1181
++D E R+ + D E +KDK K+ ++ +
Sbjct: 778 RERDKE--------------------RERQRDWE------DKDKGRDDRREKREEIREDR 811
Query: 1182 GKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTG 1241
+ G E S + +E S K+ + S
Sbjct: 812 NPRDGHDERKSKKRYRNEGSPSPRQSPKRRR------------------------EHSPD 847
Query: 1242 GSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEE----- 1296
++K + R + + + + + +P+ + + Q +W ++D + E
Sbjct: 848 SDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSH----LTEDRQGRWKEEDRKPERKESSR 903
Query: 1297 --EDVKSTQPISSVGKP---ASVIKNVSTKPSNIVKYPEKES-EPSEKIQKFTKDVSHEI 1350
E+ + + +SSV K ++++ + +I+ + + E E S++ K +
Sbjct: 904 RYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQ 963
Query: 1351 IQHEVKSSKNSASSEKG--KTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1408
+ K ++ E+G +T D V + +K+K+ + K+S D
Sbjct: 964 KKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQ 1023
Query: 1409 LSQSSKEART---SDKHDSTRASSNKD-FTPNRDKKTDYDTREYSSSKRRDEKNELTRRK 1464
S+ + RT + K + + K+ + KK D ++S D + E+T +
Sbjct: 1024 QSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPD-RTEVTEAE 1082
Query: 1465 DSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEET 1524
+ + + G P P + + + ++ T T
Sbjct: 1083 HTATA---TTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITIST 1139
Query: 1525 KSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQL 1584
+ N NN ++ + +VE +T + D KP Q
Sbjct: 1140 SATPTN-----------TTNNTFANEDSHRKCHRTRVEKVETPHVTIE-DAQHRKPMDQK 1187
Query: 1585 SHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLD 1644
SS S+ R N+S S ++ SG K + +++
Sbjct: 1188 RSSSLGSNRSNRSHTSGRLRSPSNDSAHRSG-----DDQSGR-----KRVLHSGSRDREK 1237
Query: 1645 TAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQ----------DSKK 1694
T ++ G +++ PSRS S +RSHSS SS ES DS+
Sbjct: 1238 TKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRD 1297
Query: 1695 KKKKKEKKKH-KKHKKHKKHKKHAGTEVELEKS-QKHKHKKKKSKKNKDKEKEKEKD 1749
+ +++++ +H ++ ++ ++ + + + +K +++ + + ++ +++E++K +D
Sbjct: 1298 RLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRD 1354
Score = 94.7 bits (234), Expect = 7e-19
Identities = 182/945 (19%), Positives = 349/945 (36%), Gaps = 105/945 (11%)
Query: 637 SREEFYREQRR-LKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSR 695
SR E E R + E ++ G S R K GS S+ S S + ++ S+
Sbjct: 539 SRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWET 598
Query: 696 SPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQG 755
YP R R R+ R ++R + R R+ R R R Q P+ QG
Sbjct: 599 RSSYPERDRYPERDNRDQARDSSFER---------RHGERDRRDNRERDQRPSSPIRHQG 649
Query: 756 ---ETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYA 812
E ER+ R V D + R D ++ER RE ER+ EK +
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 813 AGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARD 872
A+ R + ER + R+ + R E+ R+
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769
Query: 873 GHNQKDNTKSKEKESENA-----PGDGKGNKHKKH---------------RKRRKGEESE 912
+++ + ++KE E G+ ++ +K RK +K +E
Sbjct: 770 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Query: 913 GFLNPELLETSRKSREP------TGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS 966
G +P R+ P +G ++N+ L R + E +
Sbjct: 830 GSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRW 889
Query: 967 VSEKDKRERDKPKAKGDKTKRKNDGSAVSKKEN---IVKPAKGPQEKVDG-----ERERS 1018
E K ER + + ++ + K S+V K+ I++ ++ + + G +RE S
Sbjct: 890 KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS 949
Query: 1019 PRS-----------EPPIKKAKEETPKTDNTKSSSSSQKDEKIT---GTPRKAHSKSAKE 1064
R+ + PIKK KE+ + ++S+ + + G +K+ K K+
Sbjct: 950 DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK 1009
Query: 1065 HQETKPVKEEKVKKDYSKD--VKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEE--- 1119
+ + +E+ + K ++ +TTKEE + N KN L++ +K +
Sbjct: 1010 SKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSD 1069
Query: 1120 KGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD-----TEKMDRTPEKDKISLSAPAKK 1174
+ V E + + + T PSP + P T P + +A A
Sbjct: 1070 EDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATS 1129
Query: 1175 IKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDY 1234
+ T + N +N +E + + EKV+ VT + +D
Sbjct: 1130 FSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETP---HVTIEDAQHRKPMDQ 1186
Query: 1235 TSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFES 1294
+SS G + R + T + + +ND+ + D K S
Sbjct: 1187 KRSSSLGSN--RSNRSHTSGR------LRSPSNDSAHRSGD--------DQSGRKRVLHS 1230
Query: 1295 EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHE 1354
D + T+ + G+ S I + + +++ S ++ + + ++
Sbjct: 1231 GSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQV---- 1286
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
S++ + + + ++RD ++E +R+++ Q E + + D+ + + + +
Sbjct: 1287 --HSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERE 1344
Query: 1415 EARTSDKH---DSTRA---SSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS 1468
R DK D R S + + +RD+ +++ + S KR + K E +D S
Sbjct: 1345 RERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLES 1404
Query: 1469 RNKDSASGQKNKPREERDLPK-KGTGDSKKSNSSPSRDRKPHDHK 1512
++DS + +K R ++DL +G ++ KS + S + + K
Sbjct: 1405 TSRDSLA--LDKERMDKDLGSVQGFEETNKSERTESLEAGDDESK 1447
Score = 80.5 bits (197), Expect = 1e-14
Identities = 221/1195 (18%), Positives = 436/1195 (36%), Gaps = 183/1195 (15%)
Query: 643 REQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRR 702
RE+ +K+E S S S S+S +S S S S+ ++ + S P +
Sbjct: 188 REEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQ 247
Query: 703 GRGKSRNYRSRSRSHGYHRSRSRSPPY-----------RRYHSRSRSPQAFRGQSPNKRN 751
R N +S+ G R+ S PP +Y + R + R R+
Sbjct: 248 QRNSKTN---QSKKKG-PRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRD 303
Query: 752 VPQGETEREYFNRYREVPPP-----------YDMKAYYGRSVDFRDPFEKERYREWERKY 800
E +RE ++ R P + + G S+ P R R Y
Sbjct: 304 F---ERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSP-SPRRKRTPSPSY 359
Query: 801 REWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPF-TRGRREDYVGGQSH---- 855
+ + A P PS + SP+R SP +GR + QSH
Sbjct: 360 QRTLTPPLR---RSASPYPSHSLS--SPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRH 414
Query: 856 --RSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKH-RKRRKGEESE 912
R G EK S + ++D + S++ + P DG+ + + R RR+ +S
Sbjct: 415 ERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSR 474
Query: 913 GFLNP-ELLETSRKSREPTGVEENK-TDSLFVLPSRDDATPVRDE---PMDAESITFKSV 967
+ E+ + SR ++E +++ T R+ R E P ++ S +
Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHL 534
Query: 968 SEKDKRERDKPKAKGD-KTKRKNDGSAVSKKENIVKPAKGPQ----EKVDGERERS---- 1018
E+ R + +++ + +++ +ND S+ P KG + ++D S
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 1019 ---PRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEK 1075
RS P + E D + SS ++ + R ++ + + P++ +
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGE-----RDRRDNRERDQRPSSPIRHQG 649
Query: 1076 VKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISK 1135
+ +D + E+ ++ +E+ + D + E+ + + E+ ++D E K +
Sbjct: 650 RNDELERDERREERRVDRVDDRR-DERARERDRERERDRERERERERERDRERE--KERE 706
Query: 1136 LEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTK 1195
LE + +R+ E D E+ DR + D+ RE ++ + +
Sbjct: 707 LERERAREREREREKERDRER-DRDRDHDR------------ERERERERDREKERERER 753
Query: 1196 EPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTK 1255
E E+ + ++E+ + + R + E R E+K
Sbjct: 754 EERERERERERERERERERERERARERDKERERQ----------------RDWEDK---- 793
Query: 1256 RTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVI 1315
++ +D E++ + D++ + +E KS + + G P+
Sbjct: 794 -------DKGRDDRREKREEI---------REDRNPRDGHDER-KSKKRYRNEGSPS--- 833
Query: 1316 KNVSTKPSNIVKYPEKESEPSEKIQK-FTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDY 1374
P K + S S+ K+ H ++ V+ ++ + S T+DR
Sbjct: 834 ------PRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQG 887
Query: 1375 SVLEKENPEKRKNSTQ-------PEKESNLDRLNEQGNFKSLSQ----------SSKEAR 1417
E++ +RK S++ EK S++D+ EQ S+ S++
Sbjct: 888 RWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRE 947
Query: 1418 TSDK-HDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASG 1476
TSD+ HD + + P + KK D E + + E ++ K G
Sbjct: 948 TSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPK----------KG 997
Query: 1477 QKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDRE 1536
QK K E++ KK GDS S+ ++ K T P TK C +
Sbjct: 998 QKKKSIEKK--RKKSKGDSDISDEEAAQQSKKKRGPRT-----PPITTKEELVEMCNGKN 1050
Query: 1537 KHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQID---------KSTVKPKPQLSHS 1587
+ +++ ++++ + P T+V + + T S + P P ++ +
Sbjct: 1051 GILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATA 1110
Query: 1588 SRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGN--ISKDLKDKIVEKAKESLDT 1645
+ + T AA ++ S + S ++ N ++D K E ++T
Sbjct: 1111 TATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVET 1170
Query: 1646 AAVV------QVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKK---K 1696
V + + + +S S S +RSH+ ++ S+ S+ S + Q +K+
Sbjct: 1171 PHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHS 1230
Query: 1697 KKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
++++K K + + K E S+ ++ S+ + + E D Q
Sbjct: 1231 GSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Score = 79.7 bits (195), Expect = 2e-14
Identities = 144/804 (17%), Positives = 300/804 (37%), Gaps = 104/804 (12%)
Query: 971 DKRERDKPKAKGDKT---KRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKK 1027
D RER K K + T KR + S+ ++ + +E + +ER+P SE +
Sbjct: 84 DLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVE 143
Query: 1028 AKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKV-KKDYSKDVKS 1086
+ +DN + + + +K + K QE +EE + KK+ S +V
Sbjct: 144 WETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVR 203
Query: 1087 EKLTTK---EEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVK 1143
KL+ + +K P K+ P + K+ RKT + + K ++ +
Sbjct: 204 SKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRT 263
Query: 1144 PSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLES 1203
PSP + D + EK K+ +I+ GK G + +E +K S
Sbjct: 264 PSPPPPIPEDIALGKKYKEKYKVK-----DRIEEKTRDGKDRG--RDFERQREKRDKPRS 316
Query: 1204 TSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTME 1263
TS G+ ++ SSS S GS +++ KRT
Sbjct: 317 TSPA-------GQHHSPISSRHHSSS---------SQSGSSIQRHSPSPRRKRT---PSP 357
Query: 1264 EYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1323
Y T P P + ++ + P+ G+ + T S
Sbjct: 358 SYQRTLTPPLR----RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRH----DHERTSQS 409
Query: 1324 NIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPE 1383
+ ++ +E ++ ++ KD E E + ++S+ + + RD ++ +
Sbjct: 410 HDRRHERREDTRGKRDRE--KDSREE---REYEQDQSSSRDHRDDREPRD----GRDRRD 460
Query: 1384 KRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY 1443
R + E + D + + + S+ +KE+R STR + + RD
Sbjct: 461 ARDTRDRRELRDSRD-MRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE 519
Query: 1444 DT-----REYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREER--DLPKKGTGDSK 1496
DT R Y + R+E + R +S + ++ + R +LP+KG+ S+
Sbjct: 520 DTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSR 579
Query: 1497 KSN-SSPSRDRKPHDHKATYDT-----KRPNEETKSVDKNPCKDREKHVLEARNNKESSG 1550
S S S + HD T + + P + + ++ +R + R+N+E
Sbjct: 580 GSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQ 639
Query: 1551 NKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNES 1610
P + + + ++++ + + ++ + RE D E
Sbjct: 640 R--------PSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRE------RER 685
Query: 1611 DSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH 1670
D E + E +D+ EK +E + R ++ +
Sbjct: 686 DRERERERERE----------RDREREKERE-----------LERERARERER-EREKER 723
Query: 1671 SPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHK 1730
+ R H +D +K+++++ +++ ++ ++ ++ ++ E E E+ + +
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERERER----ERERERERARE 779
Query: 1731 HKKKKSKKNKDKEKEKEKDDQKVK 1754
K++ ++ ++K+K +DD++ K
Sbjct: 780 RDKERERQRDWEDKDKGRDDRREK 803
Score = 72.8 bits (177), Expect = 3e-12
Identities = 145/766 (18%), Positives = 285/766 (37%), Gaps = 110/766 (14%)
Query: 1005 KGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPR-KAHSKSAK 1063
+ P+ RER + + P+ NT+ SSS + E G R K K K
Sbjct: 76 RSPERPTGDLRERMKNKRQDV----DTEPQKRNTEESSSPVRKESSRGRHREKEDIKITK 131
Query: 1064 EHQETKPVKEEKVKKDYSKDVKSE---------KLTTKEEKAKKPNEKNKPLDNKGEKRK 1114
E T +EE V+ + ++D +L+ + ++ K E K EKR+
Sbjct: 132 ER--TPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKRE 189
Query: 1115 RKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKK 1174
+K V + S K+S SPKRK P + + K ++S+P
Sbjct: 190 EIIIKKEVSPEVVRS--KLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTS-AVSSPLLD 246
Query: 1175 IKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDY 1234
+ N +T + S + T P + + K+ K K KV+ ++ +
Sbjct: 247 QQRNSKTNQ---SKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIE----------EK 293
Query: 1235 TSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN-----NDNTAPAEDVIIMIQVPQSKWDK 1289
T G + EK D R+ + ++ + +++ I P + +
Sbjct: 294 TRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKR 353
Query: 1290 DDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHE 1349
S + + T P+ ++ S PS+ + P+++ P + H+
Sbjct: 354 TPSPSYQRTL--TPPLR---------RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHD 402
Query: 1350 IIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSL 1409
HE S + DR + E E + EK+S +R EQ
Sbjct: 403 ---HERTSQSH----------DRRH-----ERREDTRGKRDREKDSREEREYEQDQ---- 440
Query: 1410 SQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR 1469
SS++ R D + +D RD++ D+R+ S+ + + T+ P
Sbjct: 441 -SSSRDHR--DDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRD 497
Query: 1470 NKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDK 1529
++ + + RE RD +K ++S S R+ + T E++S +
Sbjct: 498 SRSTRDAHDYRDREGRDTHRKEDTYPEESRSY-GRNHLREESSRTEIRNESRNESRSEIR 556
Query: 1530 NPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSR 1589
N R + + K S G++ QID SHSS
Sbjct: 557 NDRMGRSRGRVPELPEKGSRGSR-----------------GSQID----------SHSSN 589
Query: 1590 LSSDLTRETDEAAFEPD-YNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV 1648
+ + ET + E D Y E D+ +SS +D+ + ++ ++ +
Sbjct: 590 SNYHDSWETRSSYPERDRYPERDNRDQA----RDSSFERRHGERDRRDNRERDQRPSSPI 645
Query: 1649 VQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK 1708
G RN R + R + E + +++++++E+++ ++ +
Sbjct: 646 RHQG--RNDELERDERREERRVDRVDDR-RDERARERDRERERDRERERERERERDRERE 702
Query: 1709 KHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754
K ++ ++ E E E+ +K + +++ ++ D+E+E+E++ + K
Sbjct: 703 KERELERERARERERER-EKERDRERDRDRDHDRERERERERDREK 747
Score = 60.5 bits (145), Expect = 1e-08
Identities = 81/403 (20%), Positives = 156/403 (38%), Gaps = 60/403 (14%)
Query: 1365 EKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDS 1424
E+ K K +D E + ++S+ KES+ R E+ + K +KE + ++
Sbjct: 87 ERMKNKRQDVDT-EPQKRNTEESSSPVRKESSRGRHREKEDIKI----TKERTPESEEEN 141
Query: 1425 TRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREE 1484
+N+D + N D DY KR+ + EL + + ++ +K E
Sbjct: 142 VEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEV 201
Query: 1485 RDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARN 1544
+ +KS+ SP R P A+ + + +T +V +P D++ RN
Sbjct: 202 VRSKLSPSPSLRKSSKSPKRKSSPKSSSAS----KKDRKTSAVS-SPLLDQQ------RN 250
Query: 1545 NKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFE 1604
+K + K P + ++ G+ K K K ++ +R D R+ + +
Sbjct: 251 SKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREK 310
Query: 1605 PDYNESDS-----ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSH 1659
D S S S +S + SS + Q H
Sbjct: 311 RDKPRSTSPAGQHHSPISSRHHSSSSQSGSSI-------------------------QRH 345
Query: 1660 SSPSVSPSRSHSPSGSQTRSHSS----SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
S SP R +PS S R+ + SAS S ++K+ +H+ + K
Sbjct: 346 SP---SPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHD 402
Query: 1716 HAGTEVELEKSQKHKHKKK---KSKKNKDKEKEKEKDDQKVKS 1755
H T +S +H+++ + K++++K+ +E++ ++ +S
Sbjct: 403 HERT----SQSHDRRHERREDTRGKRDREKDSREEREYEQDQS 441
Score = 44.7 bits (104), Expect = 8e-04
Identities = 87/436 (19%), Positives = 150/436 (34%), Gaps = 79/436 (18%)
Query: 571 TLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPT 630
T P P P S PP A + P A +T + +S + + S T
Sbjct: 1086 TATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTN 1145
Query: 631 TQAPPLSREEFYREQRRLK-EESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSH 689
T + E+ +R+ R + E+ ++P+ ++ + RS S S +RS +
Sbjct: 1146 TTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGR 1205
Query: 690 SRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNK 749
RS S + R S S +++S R +SR Q RG+ P++
Sbjct: 1206 LRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGER---KSRIDQLKRGE-PSR 1261
Query: 750 RNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDF--------RDPFEKERYREWER--- 798
+ R + +R P + + RS F RD +E +R RE ER
Sbjct: 1262 STSSDRQDSRSHSSRRSS---PESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDT 1318
Query: 799 KYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSR 858
+ REW K + PR NR+
Sbjct: 1319 RQREWDRDADKDW-----PR---NRDR--------------------------------- 1337
Query: 859 NIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPE 918
++L R+ ++D + ++E E D + + R R + ES + +
Sbjct: 1338 -------DRLRERERERERDKRRDLDRERERLISDSV--ERDRDRDRDRTFESSQIESVK 1388
Query: 919 LLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKP 978
E + +E DSL + E MD + + + E +K ER +
Sbjct: 1389 RCEAKLEGEHERDLESTSRDSL----------ALDKERMDKDLGSVQGFEETNKSERTES 1438
Query: 979 KAKGDKTKRKNDGSAV 994
GD + +D ++
Sbjct: 1439 LEAGDDESKLDDAHSL 1454
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 104 bits (260), Expect = 7e-22
Identities = 192/937 (20%), Positives = 351/937 (37%), Gaps = 156/937 (16%)
Query: 866 EKLSARDGHNQKDNTKSKEKESENAPG----DGKGNKHKKHRKRRKGEESEGFLNPELLE 921
++ SA + N K+ E+ S+ P D +K + E+S E LE
Sbjct: 213 QEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLE 272
Query: 922 TSRKSRE----PTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDK 977
T+ KS E P VEE K + + + + K V ++ +++K
Sbjct: 273 TAPKSEEFSDLPCPVEEIKNYT---------------KEHNNLILLNKDVQQESSEQKNK 317
Query: 978 PKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDN 1037
KG+K N+ KKE K K E + + E K+AKE+ ++
Sbjct: 318 STDKGEKKPDSNE-KGERKKEKKEKTEKKFDHSKKSEDTQKVKDE---KQAKEKEVESLK 373
Query: 1038 TKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
S +S K + + GT + + + + V ++ D+ S + T+EE
Sbjct: 374 LPSEKNSNKAKTVEGTKEDFSLIDS----DVDGLTDITVSSVHTSDLSSFEEDTEEEVVT 429
Query: 1098 KPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKM 1157
+ + + + E++ ++ + K D SS K + + KP K D++
Sbjct: 430 SDSMEEGEITSDDEEKNKQNKTKTQTSD--SSEGKTKSVRHAYVHKPYLYSKYYSDSDD- 486
Query: 1158 DRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKV 1217
+ T E+ + S++ ++ L R+ N ++ EK + + K K K KG+
Sbjct: 487 ELTVEQRRQSIAKEKEERLLRRQI-----------NREKLEEKRKQKAEKTKSSKTKGQG 535
Query: 1218 RRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVI 1277
R V E S+ +L E K + V+K E +
Sbjct: 536 RSSVDLEESSTKSL-----------------EPKAARIKEVLK-------------ERKV 565
Query: 1278 IMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKP----SNIVKYPEKES 1333
+ +V SK K D + EE+ K Q K K S +K+ +S
Sbjct: 566 LEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKS 625
Query: 1334 EPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEK 1393
EPS+ ++ ++ + H V +KN S LE+E+ KR+ ST
Sbjct: 626 EPSKPARRLSESL------HVVDENKNE-------------SKLEREH--KRRTSTPVIM 664
Query: 1394 ESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKR 1453
E + E+ + + + + + + + + S+ K+ KK D +T S +
Sbjct: 665 EG----VQEETDTRDVKRQVERSEICTEEPQKQKSTLKN--EKHLKKDDSETPHLKSLLK 718
Query: 1454 RDEKN--ELTRRKDSPSRNKDSASGQ-----KNKPREERDL--PKKGTGDSKKSNSSPSR 1504
++ K+ E R+ +PS +K S + +K +E +L +KG + +
Sbjct: 719 KEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQ 778
Query: 1505 DRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQV 1564
+ D K +K NE SV K +++++ N NK L+ +T+
Sbjct: 779 TKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKA 838
Query: 1565 E---KEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKE- 1620
E + +I K ++ K R S + + + D + ++ +SN+ +E
Sbjct: 839 EHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSED------KCDMDSTNMDSNLKPEEV 892
Query: 1621 -EESSGNISKDLKDKIVEKAKESLDTAAV------VQVGISRNQSHSSPSVSPSRSHSPS 1673
+ L++K+V K+K V +Q G ++ + P + + S
Sbjct: 893 VHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDS 952
Query: 1674 GSQTRSH------------------SSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
Q +S SSSA S + S + K K+K+K K
Sbjct: 953 EKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDS----- 1007
Query: 1716 HAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1752
T +E + S HK + K K+K++ K D K
Sbjct: 1008 -TSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDK 1043
Score = 91.7 bits (226), Expect = 6e-18
Identities = 176/863 (20%), Positives = 324/863 (37%), Gaps = 122/863 (14%)
Query: 881 KSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSL 940
+S KE E + N+ K KR++ E + +T + R +EE+ T SL
Sbjct: 495 QSIAKEKEERLLRRQINREKLEEKRKQKAEKT-----KSSKTKGQGRSSVDLEESSTKSL 549
Query: 941 FVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENI 1000
+R E + + K V+ KR++D ++ +K KE +
Sbjct: 550 EPKAARIK------EVLKERKVLEKKVALSKKRKKDSRNV--EENSKKKQQYEEDSKETL 601
Query: 1001 VKPAKGPQEKVDGERERS---PRSEP--PIKKAKEETPKTDNTKSSSSSQKDEKI-TGTP 1054
+EK+ +E +SEP P ++ E D K+ S +++ K T TP
Sbjct: 602 KTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTP 661
Query: 1055 RKAHSKSAKEHQETKPVK----------------------EEKVKKDYSKDVKSEKLTTK 1092
+ +E +T+ VK E+ +KKD S+ + L K
Sbjct: 662 --VIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKK 719
Query: 1093 EEKA--KKPNEKNKPLDNK---GEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPK 1147
E K+ +KP + P ++K K K K D+ SS K K+E I K S +
Sbjct: 720 EVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVE-ENIQKQSQQ 778
Query: 1148 RKMEPDTEKMDRTPEKDKISLSAPAKK--------IKLNRETGKKIGSTE---NISNTKE 1196
K+ D + ++ +++ LS K IK + K+ E + TK
Sbjct: 779 TKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKA 838
Query: 1197 PSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKR 1256
+ S+ SK++++ + G + +T S S D ST K EE ++
Sbjct: 839 EHKSRRSSDSKIQKDSL-GSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEK 897
Query: 1257 TVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIK 1316
K++ E E +++ K + ++ V T+ K A+
Sbjct: 898 RRTKSLLE---------EKLVLK--------SKSKTQGKQVKVVETELQEGATKQAT--- 937
Query: 1317 NVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSV 1376
+ KP E +SE K + K ++ ++++ +SA S + + R
Sbjct: 938 --TPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLP 995
Query: 1377 LEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPN 1436
L KE + K+ST E +L++ +SL SSK+ + D+
Sbjct: 996 LAKEKYKSDKDSTSTRLER---KLSDGHKSRSLKHSSKDIKKKDE--------------- 1037
Query: 1437 RDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSK 1496
+K D D +E SS + N K R ++ G ++ + + S
Sbjct: 1038 -NKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLST 1096
Query: 1497 KSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYI 1556
S SS R +K D T P +E +D P + V + ++N+ ++ + +
Sbjct: 1097 PSGSSLQRPKKSGDM-----TLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDS 1151
Query: 1557 LNPPE---TQVEKEQI-TGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAF---EPDYNE 1609
N + V+K+++ T D P + + ++S+ + D + +
Sbjct: 1152 ENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQS 1211
Query: 1610 SDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRS 1669
+ S+ N KE G ++ + V + L +A + +N +++ +
Sbjct: 1212 AVSKMNPGEKEPIHRGTTEVNIDSETVHR---MLLSAPSENDRVQKNLKNTA-----AEE 1263
Query: 1670 HSPSGSQTRSHSSSASSAESQDS 1692
H G T HS++ S+ S S
Sbjct: 1264 HVAQGDATLEHSTNLDSSPSLSS 1286
Score = 80.5 bits (197), Expect = 1e-14
Identities = 148/665 (22%), Positives = 244/665 (36%), Gaps = 102/665 (15%)
Query: 1152 PDTEKMDRTPEKDKISLSAPAKKI------------KLNRETGKKIGSTENISNTKEPSE 1199
PD EK D + + P+ + LN+E STE SN K
Sbjct: 174 PDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEASAARASTET-SNAK---- 228
Query: 1200 KLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYT-STSSTGGSPVR---KSEEKTDTK 1255
TS + ++ T E +S + D ST+ +GG + KSEE +D
Sbjct: 229 ----TSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLP 284
Query: 1256 RTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVI 1315
V EE N +++ V Q ES E+ KST KP S
Sbjct: 285 CPV----EEIKNYTKEHNNLILLNKDVQQ--------ESSEQKNKSTD--KGEKKPDSNE 330
Query: 1316 KNVSTKPSNIVKYPE----KESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKD 1371
K K + K+SE ++K++ + E+ ++ S KNS ++ +
Sbjct: 331 KGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTK 390
Query: 1372 RDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNK 1431
D+S+++ + + S+L E + ++ S E D + NK
Sbjct: 391 EDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNK 450
Query: 1432 DFTPNRDKKTD--------YDTREYSSSKR-RDEKNELT--RRKDSPSRNKDSASGQKNK 1480
T D Y + Y SK D +ELT +R+ S ++ K+ ++
Sbjct: 451 TKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQI 510
Query: 1481 PREERDLPKKGTGDSKKSNSSPSRDRKPHD-HKATYDTKRPN--------EETKSVDKNP 1531
RE+ + +K + KS+ + + R D +++ + P +E K ++K
Sbjct: 511 NREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKV 570
Query: 1532 CKDREKHVLEARNNKESSGNKLLYILNPPET-----QVEKEQITGQIDKSTVKPKPQLSH 1586
+ K ++RN +E+S K Y + ET EKE+I+ + V K + S
Sbjct: 571 ALSK-KRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSK 629
Query: 1587 SSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTA 1646
+R S+ DE N S E E S + I+E +E DT
Sbjct: 630 PARRLSESLHVVDE------------NKNESKLEREHKRRTSTPV---IMEGVQEETDTR 674
Query: 1647 ----AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKK--- 1699
V + I + S + H H S E + SK+K +++
Sbjct: 675 DVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTP 734
Query: 1700 -EKKKHKKHKKHKKHKKHAGTEVELEKS----------QKHKHKKKKSKKNKDKEKEKEK 1748
E K KHK G E EL S QK + K S +K + K K +
Sbjct: 735 SEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHR 794
Query: 1749 DDQKV 1753
+++K+
Sbjct: 795 NERKL 799
Score = 66.2 bits (160), Expect = 3e-10
Identities = 77/359 (21%), Positives = 148/359 (41%), Gaps = 39/359 (10%)
Query: 834 LNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGD 893
LN+ NS F R + + +S+ I S + A GH+ + + K E+E + P
Sbjct: 2715 LNVENSGF---RTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPK- 2770
Query: 894 GKGNKHKKHRKRRKGEESEGFLNPELL----ETSRKS---REPTGVEENKTDSLFVLPSR 946
K K+H + E + NP++L ET+++ EP +E + L LP
Sbjct: 2771 ---RKRKQHYLSSEDEPDD---NPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKT 2824
Query: 947 DDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKEN---IVKP 1003
T S T + + EKD E + G+K ++ +D + S++E+ I+K
Sbjct: 2825 SSET---------NSTTSRVMEEKD--EYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKR 2873
Query: 1004 AKGPQEKVDGERERSPRSEPPIKKA---KEETPKTDNTKSSSSSQKDEKITGTPRKAHSK 1060
+G K E + + E++P + K + + +++ ++ S
Sbjct: 2874 KRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISN 2933
Query: 1061 SAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEK 1120
E + V+ K S V + +++ E+ ++ + + D K ++ + EE+
Sbjct: 2934 DDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEE 2993
Query: 1121 GVDKDFESSSMKISKLEVTEI---VKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIK 1176
D+ +++ ++ E + PS KRK E RT + ++ AP KK K
Sbjct: 2994 EEDEPSGATTRSTTRSEAQRSKTQLSPSIKRKREVSPPGA-RTRGQQRVE-EAPVKKAK 3050
Score = 56.2 bits (134), Expect = 3e-07
Identities = 81/397 (20%), Positives = 158/397 (39%), Gaps = 61/397 (15%)
Query: 1310 KPASVIKNVSTKPSNIVKYPEKESEPSEK--IQKFTKDVSHEIIQHEVKSSKNSASSEKG 1367
+P V ++++ + S E SE K I KD + I H V++ E
Sbjct: 2707 EPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEE-- 2764
Query: 1368 KTKDRDYSVLEKENPEKRKN----STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHD 1423
E+ P++++ S++ E + N D L+ + + + ++ ++ HD
Sbjct: 2765 ----------ERHMPKRKRKQHYLSSEDEPDDNPDVLDSR-----IETAQRQCPETEPHD 2809
Query: 1424 STRASSNKDFT--PNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKP 1481
T+ +++D P +T+ T K +E T K P +N D K++
Sbjct: 2810 -TKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEK--PEQNDDDTI--KSQE 2864
Query: 1482 REERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLE 1541
++ + K+ G +K + K D + + +V+++P + K +
Sbjct: 2865 EDQPIIIKRKRGRPRKYPVETTLKMK--------DDSKTDTGIVTVEQSPSSSKLKVMQT 2916
Query: 1542 ARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRL-SSDLTRETDE 1600
+NKE++ + I N +E+I + + KPK L+ S SS+ R+ +
Sbjct: 2917 DESNKETANLQERSISNDDG----EEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQK 2972
Query: 1601 AAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHS 1660
+ +P ++ + ES+ +EEE E T + + R+++
Sbjct: 2973 SVSDPVEDKKEQESDEEEEEEE--------------EDEPSGATTRSTTRSEAQRSKTQL 3018
Query: 1661 SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1697
SPS+ R SP G++TR E KK K+
Sbjct: 3019 SPSIKRKREVSPPGARTRGQ----QRVEEAPVKKAKR 3051
Score = 42.4 bits (98), Expect = 0.004
Identities = 62/337 (18%), Positives = 135/337 (40%), Gaps = 69/337 (20%)
Query: 1439 KKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQ------KNKPREERDLPKKGT 1492
+ + + T E S+ ++ + RKD N ++ SG K EER +PK+
Sbjct: 2718 ENSGFRTNEEIHSESYNKGEISSGRKD----NAEAISGHSVEADPKEVEEEERHMPKR-- 2771
Query: 1493 GDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNK 1552
K+ S + +P D+ D++ + + C + E H + N+++
Sbjct: 2772 ---KRKQHYLSSEDEPDDNPDVLDSRIETAQRQ------CPETEPHDTKEENSRD----- 2817
Query: 1553 LLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDS 1612
+ P+T E T ++ ++ K + S SS+ T E +P+ N+ D+
Sbjct: 2818 ---LEELPKTSSETNSTTSRV----MEEKDEYS-----SSETTGE------KPEQNDDDT 2859
Query: 1613 ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSP 1672
+K +E I+ K K V+ + + + + SP
Sbjct: 2860 -----IKSQEED--------QPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSP 2906
Query: 1673 SGSQTRSHSSSASSAESQDSKKKKKKKEKKKHK----KHKKHKKHKKHAGTEVELEKSQK 1728
S S+ + + S+ E+ + +++ + + K ++ +K K+ + E S+
Sbjct: 2907 SSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEP 2966
Query: 1729 HKHKKK--------KSKKNKDKEKEKEKDDQKVKSVT 1757
+ ++K K ++ D+E+E+E++D+ + T
Sbjct: 2967 ERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATT 3003
Score = 41.6 bits (96), Expect = 0.007
Identities = 66/331 (19%), Positives = 126/331 (38%), Gaps = 42/331 (12%)
Query: 1437 RDKKTDYDTRE-YSSSKRRDEK---NELTRRKDSPSRNKDSASGQKNKPREERDLPKKGT 1492
RD D DT+ Y + ++R + N L SP NK+ + + + + G
Sbjct: 72 RDCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGI 131
Query: 1493 G-------DSKKSNS-SPSRDRKPHDHKATYDTKRPNE-ETKSVDKNPCKDREKHVLEAR 1543
D K +++ P ++ H+ AT + K T D+ P +
Sbjct: 132 DRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEGSGNTAPDDEKPDTSLITQGVPTP 191
Query: 1544 NNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAF 1603
+ N + IL T + +E + T K S +L S T +T
Sbjct: 192 GPSANVANDAMSILETI-TSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTST--- 247
Query: 1604 EPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPS 1663
++ + +++ KE+ ++ + + L+ K++E D V+ + + H++
Sbjct: 248 ----DKERTSEDMADKEKSTADSGGEGLET--APKSEEFSDLPCPVEEIKNYTKEHNNLI 301
Query: 1664 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVEL 1723
+ + SS + + +KK EK + KK KK K KK
Sbjct: 302 LL--------NKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF------- 346
Query: 1724 EKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754
H K + ++K KD+++ KEK+ + +K
Sbjct: 347 ----DHSKKSEDTQKVKDEKQAKEKEVESLK 373
Score = 40.4 bits (93), Expect = 0.015
Identities = 66/294 (22%), Positives = 96/294 (32%), Gaps = 46/294 (15%)
Query: 1466 SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETK 1525
S +R S K R + LP + T D+ S D + K+T D+ ET
Sbjct: 216 SAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKE-KSTADSGGEGLETA 274
Query: 1526 SVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLS 1585
+ D V E +N + N L +LN Q EQ DK KP
Sbjct: 275 PKSEE-FSDLPCPVEEIKNYTKEHNN--LILLNKDVQQESSEQKNKSTDKGEKKP----- 326
Query: 1586 HSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK---ES 1642
S + +E E + + SE VK+E K K+K VE K E
Sbjct: 327 -DSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDE-------KQAKEKEVESLKLPSEK 378
Query: 1643 LDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKK 1702
A G + S V + S T SS E +
Sbjct: 379 NSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEE------------ 426
Query: 1703 KHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
T +E+ + ++K+K+NK K + + + K KSV
Sbjct: 427 --------------VVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSV 466
Score = 36.2 bits (82), Expect = 0.29
Identities = 20/39 (51%), Positives = 20/39 (51%), Gaps = 6/39 (15%)
Query: 558 PVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAG 596
P PPPP PPPP P P PPP P PG P AG
Sbjct: 7 PQPPPPAPPPPP---PQPQPQPPP---PPPGPGAGPGAG 39
Score = 33.1 bits (74), Expect = 2.4
Identities = 20/46 (43%), Positives = 21/46 (45%), Gaps = 11/46 (23%)
Query: 558 PVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPG 603
P P PP PPP PPPQ PQ PP PPP + P G
Sbjct: 5 PQPQPPPPAPPP---------PPPQPQPQPPP--PPPGPGAGPGAG 39
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 103 bits (258), Expect = 1e-21
Identities = 186/809 (22%), Positives = 318/809 (39%), Gaps = 126/809 (15%)
Query: 917 PELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERD 976
P + +T K R + E+ + LPS+ ++E + + K + ++
Sbjct: 528 PVVKQTKLKQRADS--RESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVE-SKE 584
Query: 977 KPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTD 1036
K K DK + +V++KE P+K V E ++ K AKE+T K +
Sbjct: 585 KVMVKKDKPIKTETKPSVTEKE---VPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKE 641
Query: 1037 NTKSSSSSQKDEKITGTPRKAHSKSAKE---HQETKPVKEEKVKKDYSKDVKSE--KLTT 1091
TK +K+EK P+K +K + +E KP KEE VKK+ K++K E K
Sbjct: 642 -TKVKPEDKKEEK--EKPKKEVAKKEDKTPIKKEEKPKKEE-VKKEVKKEIKKEEKKEPK 697
Query: 1092 KEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFES--SSMKISKLEVTEIVKPSPKRK 1149
KE K + P ++ K K EK++ K EEK K+ + K S ++E KP+
Sbjct: 698 KEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPA---A 754
Query: 1150 MEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVK 1209
++P K + + +KD ++ P +K K+K
Sbjct: 755 LKPKVPKKEESVKKDSVAAGKPKEK-------------------------------GKIK 783
Query: 1210 QEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND- 1268
K +GK V G+ +T + + G ++ + +R+++ + E+ D
Sbjct: 784 VIKKEGKAAEAVAAAVGTGATT---AAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDF 840
Query: 1269 NTAPAEDVIIMIQV-PQSKWDKDDFESEEEDVKSTQPISS--VGKPASVIKNVSTKPSNI 1325
AE+V + + PQ + +D EE +K T+P+ + + K V K + P
Sbjct: 841 EELKAEEVDVTKDIKPQLELIED-----EEKLKETEPVEAYVIQKEREVTKGPAESPDEG 895
Query: 1326 VKYPE---------KESEPSEK-----IQKFTK-----DVSHEIIQHEVKSSKNSA---- 1362
+ E +E EP EK I+KF + S E +E K+ A
Sbjct: 896 ITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPE 955
Query: 1363 ----------SSEKGKTKDRDYSVLEKEN--PEKRKN--STQPEKESNLDRLNEQGNFKS 1408
+S+ T+D + + E + EKR++ S E ++D E+G
Sbjct: 956 EDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKG---E 1012
Query: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS 1468
QS +EA DK + R +++ P + + DY + E +P+
Sbjct: 1013 AEQSEEEADEEDKAEDAR---EEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPT 1069
Query: 1469 RNKDSASGQKNKPREERDLPKKGTGDSKKSNS-SPSRDRKPHDHKATYDTKRPNEETKSV 1527
+ + S + D G +S+ + S +R+ +P + AT + E S
Sbjct: 1070 KQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISS- 1128
Query: 1528 DKNPCKDRE--KHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDK-STVKPKPQL 1584
+ P + + V+ N E + + +N T+ E + + K + V P
Sbjct: 1129 EPTPMDEMSTPRDVMSDETNNEETESPSQEFVN--ITKYESSLYSQEYSKPADVTPLNGF 1186
Query: 1585 SHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLD 1644
S S+ +A DYN S S + EE + S L+D + K S
Sbjct: 1187 SEGSK---------TDATDGKDYNASASTISPPSSMEEDKFSRSA-LRDAYCSEVKAS-- 1234
Query: 1645 TAAVVQVGISRNQSHS-SPSVSPSRSHSP 1672
T ++ IS S SPS SPS S SP
Sbjct: 1235 TTLDIKDSISAVSSEKVSPSKSPSLSPSP 1263
Score = 51.2 bits (121), Expect = 9e-06
Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 8/197 (4%)
Query: 1561 ETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKE 1620
+T++++ + + K KP P S S + T E + + +S+ V VK+
Sbjct: 532 QTKLKQRADSRESLKPAAKPLPSKSVRKE-SKEETPEVTKVNHVEKPPKVESKEKVMVKK 590
Query: 1621 EESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPS-GSQTRS 1679
++ I + K + EK S + + V+ ++ Q+ V P + + +T+
Sbjct: 591 DKP---IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQA---TDVKPKAAKEKTVKKETKV 644
Query: 1680 HSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN 1739
+ + K+ KK++K KK +K KK + + E++K +K + KK+ K+
Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Query: 1740 KDKEKEKEKDDQKVKSV 1756
KE +KE ++ K V
Sbjct: 705 PPKEVKKEVKKEEKKEV 721
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/180 (22%), Positives = 75/180 (41%), Gaps = 6/180 (3%)
Query: 1573 IDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE-SSGNISKDL 1631
+ K + + P+++ + + E+ E +E+ SV E+E S +
Sbjct: 557 VRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPV 616
Query: 1632 KDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQD 1691
K ++ EK + A + + + ++ P P + + E +
Sbjct: 617 KAEVAEKQATDVKPKAAKEKTVKK-ETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 1692 SK---KKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEK 1748
K KK+ KKE KK +K K+ KK K E++K K + KK+ K+ K+ +KE +K
Sbjct: 676 KKEEVKKEVKKEIKKEEK-KEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKK 734
Score = 43.5 bits (101), Expect = 0.002
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 944 PSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK-----RKNDGSAVSKKE 998
P D + V E + E K++ +KD +E+ K K G KTK +K+DG +
Sbjct: 2212 PRHPDVSMVDPEALAIEQNLGKAL-KKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAA 2270
Query: 999 NIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAH 1058
+ KPA + R SP+ + ++KA + T T K++ +KD++ +
Sbjct: 2271 S-PKPAGLKESSDKVSRVASPKKKESVEKAAKPT-TTPEVKAARGEEKDKETKNAANASA 2328
Query: 1059 SKSAK 1063
SKSAK
Sbjct: 2329 SKSAK 2333
Score = 38.5 bits (88), Expect = 0.058
Identities = 105/520 (20%), Positives = 179/520 (34%), Gaps = 114/520 (21%)
Query: 866 EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEE----SEGFLNPELLE 921
EK D +D E+ SE + K + GEE S +P E
Sbjct: 916 EKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDE 975
Query: 922 TSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAK 981
S K+ + E + + S DD +E MD E+I K +E+ + E D+
Sbjct: 976 ESAKAEADAYIREKRES----VASGDDRA---EEDMD-EAIE-KGEAEQSEEEADEEDKA 1026
Query: 982 GDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERE-------------RSPRSEPPIKKA 1028
D + + + + ++ ++ E E + +SP EP
Sbjct: 1027 EDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIH 1086
Query: 1029 KEETP---KTDNTKSSSSSQKDEKITGTPRKAHSKSAKE-HQETKPVKEEKVKKDYSKDV 1084
E P +++ T S +++D+ T +++S E E P+ E +D D
Sbjct: 1087 DETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDE 1146
Query: 1085 KSEKLT----------TKEEKAKKPNEKNKPLDN---KGEKRKRKTEEKGVDKDFESSSM 1131
+ + T TK E + E +KP D G KT+ KD+ +S+
Sbjct: 1147 TNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATD-GKDYNASAS 1205
Query: 1132 KISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAK-----KIKLNRETGKKIG 1186
IS P ME D K R+ +D A K ++ + +K+
Sbjct: 1206 TIS-----------PPSSMEED--KFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVS 1252
Query: 1187 STENISNTKEPSEKLEST---------------------------SSKVKQEKVKGKVR- 1218
+++ S + P LE T S +V QE V+
Sbjct: 1253 PSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCAS 1312
Query: 1219 ------------RKVTGTEGSSSTLVDYTSTSSTG----------GSPV--RKSEEKTDT 1254
+ VTG+ G + T S+ PV S+ K +
Sbjct: 1313 PEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDEN 1372
Query: 1255 KRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFES 1294
+R + M+E D+ +P E V+ ++ P + +ES
Sbjct: 1373 ERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYES 1412
Score = 35.4 bits (80), Expect = 0.49
Identities = 59/267 (22%), Positives = 99/267 (37%), Gaps = 47/267 (17%)
Query: 1497 KSNSSPSRDRKPHDHKATYDTKRPNEETKS---VDKN-PCKDREKHVLEARN--NKESSG 1550
KS S++ P K + K P E+K V K+ P K K + + +KE
Sbjct: 555 KSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEP- 613
Query: 1551 NKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFE-PDYNE 1609
+P + +V ++Q T VKPK + + + + E + E P
Sbjct: 614 -------SPVKAEVAEKQATD------VKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEV 660
Query: 1610 SDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRS 1669
+ E +K+EE K K+++ ++ K+ + + + P +
Sbjct: 661 AKKEDKTPIKKEE------KPKKEEVKKEVKKEI-----------KKEEKKEPKKEVKKE 703
Query: 1670 HSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKH 1729
P E + KK++K+ KK+ KK K K +E + + K
Sbjct: 704 TPPK------EVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKP 757
Query: 1730 KHKKKKSKKNKDK---EKEKEKDDQKV 1753
K KK+ KD K KEK KV
Sbjct: 758 KVPKKEESVKKDSVAAGKPKEKGKIKV 784
Score = 33.1 bits (74), Expect = 2.4
Identities = 58/237 (24%), Positives = 79/237 (33%), Gaps = 28/237 (11%)
Query: 904 KRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPS---------RDDATPVRD 954
K K E S F+NP LE S EPT E P + D TP
Sbjct: 2091 KHPKTELSPSFINPNPLEWFA-SEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTS 2149
Query: 955 EPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIV--KPAKGPQEKVD 1012
A S T V + + + P D D S + V K P V
Sbjct: 2150 VSESAPSQTDSDVPPETE---ECPSITADANIDSEDESETIPTDKTVTYKHMDPPPAPVQ 2206
Query: 1013 GERERSPRSEPPIKKAKEETPKTDNT-----KSSSSSQKDEKITGTPRKAHSKSAKEHQE 1067
+R SPR P + E + K + K GT K+ S K +
Sbjct: 2207 -DRSPSPR-HPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGK 2264
Query: 1068 TKPVKEE------KVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTE 1118
+KP+ K D V S K EKA KP + +GE++ ++T+
Sbjct: 2265 SKPLAASPKPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETK 2321
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 102 bits (254), Expect = 3e-21
Identities = 199/960 (20%), Positives = 364/960 (37%), Gaps = 154/960 (16%)
Query: 594 PAGYSVPPPGFPPAPANLSTPWVSS-------GVQTAHSNTIPTTQAPPLSRE----EFY 642
P S PP + P PW S +T H I +T + +E Y
Sbjct: 609 PLSDSPPPSRWKPG----QKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSY 664
Query: 643 REQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSH----SRSYSRSPP 698
++ + E +S YS S RSS + +SRS S+RSRSYSRS++RS S S SRSP
Sbjct: 665 HKREKNSESDQSTYSKYS-DRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPS 723
Query: 699 YPRRGRGKSRNYRSRSRSHGY--------HRSRSRSPPYRRYHSRSRSPQAFRGQSPNKR 750
R K ++ SRS Y R++ R + +S S + +
Sbjct: 724 SRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHS 783
Query: 751 NVPQGETEREYFNRYREVPPPYDMKAYYGRS--VDFRDPFEKERYREWERKYREWYEKYY 808
+G +Y E D + +S + EKE+ + ER + + ++
Sbjct: 784 KYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK--QEKN 841
Query: 809 KGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVG----GQSHRSRNIGSNY 864
+G R + + + + L ++RN ++ +R++Y G +S+ R++ N
Sbjct: 842 RGEEKSKSERECPHSKKRTLKENLSDHLRNG--SKPKRKNYAGSKWDSESNSERDVTKN- 898
Query: 865 PEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 924
++ D+ S +KE A D + + H K ++ +
Sbjct: 899 ----------SKNDSHPSSDKEEGEATSDSESEVSEIHIK---------------VKPTT 933
Query: 925 KSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984
KS T + ++ ++ R D+E S + + K ++ K +K +
Sbjct: 934 KSSTNTSLPDDN--------GAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSK-EN 984
Query: 985 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1044
KR++ K + +K K + K +R+++ +PP++ +EE + D+ K +
Sbjct: 985 LKREH----TKKVKEKLKGKKDKKHKAP-KRKQAFHWQPPLEFGEEEEEEIDD-KQVTQE 1038
Query: 1045 QKDEKIT---GTPRKAHSKSAKEHQETKPVKEE--KVKKDYSKDVKSEKLTTKEEKAKKP 1099
K++K++ T + K+ K +E K + V D + K + + A
Sbjct: 1039 SKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNT 1098
Query: 1100 NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDR 1159
E L N + E+ V E +E+ + SP K++
Sbjct: 1099 EENVACLQN------IQHVEESVPNGVEDVLQTDDNMEICTPDRSSP--------AKVEE 1144
Query: 1160 TPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRR 1219
T L P I L ++ T+ P ++ S + + KV G+V
Sbjct: 1145 TSPLGNARLDTPDINIVLKQDMA-----------TEHPQAEVVKQESSMSESKVLGEV-- 1191
Query: 1220 KVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN--------NDNTA 1271
G + SSS S +S G S +K + + K + N T+
Sbjct: 1192 ---GKQDSSS-----ASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATS 1243
Query: 1272 PAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEK 1331
A +V ++ VP+ K + ++KS + +P S+ V K + + + P
Sbjct: 1244 SAVEVKVLTTVPEMK-----PQGLRIEIKSKNKV----RPGSLFDEV-RKTARLNRRPRN 1293
Query: 1332 ESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQP 1391
+ S++ D S + +S S S + K++ R SV + + ++ST
Sbjct: 1294 QESSSDEQTPSRDDDS------QSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSS 1347
Query: 1392 EKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRA-SSNKDFTPNRDKKTDYDTREYSS 1450
+ + R +G + RT + S R+ S++ + +R + + YD S
Sbjct: 1348 YRSRSYSRSRSRGWY-------SRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSR 1400
Query: 1451 SKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHD 1510
S D +R S SR++ S S + + R + G +S+ S S R P +
Sbjct: 1401 SYTYDSYYSRSR---SRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Score = 95.5 bits (236), Expect = 4e-19
Identities = 182/922 (19%), Positives = 358/922 (38%), Gaps = 110/922 (11%)
Query: 866 EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRK 925
+K + +G + N+ S + S + + + ++ +KH++R P++ + ++
Sbjct: 190 KKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRR-----------PKVKRSKKR 238
Query: 926 SREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKT 985
+E + EE P A + +++ +SV KRE KP + ++
Sbjct: 239 RKEASSSEE---------PRNKHAMNPKGHSERSDTNEKRSVDSSAKRE--KPVVRPEEI 287
Query: 986 KRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETP-------KTDNT 1038
+ + +++ V A+ P+ K+ +P + K+ + T
Sbjct: 288 PPVPENRFLLRRDMPVVTAE-PEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPR 346
Query: 1039 KSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKS----EKLTTKEE 1094
S S D+ + TP + + P E+ K D D S E+ ++
Sbjct: 347 SRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRS 406
Query: 1095 KAKKPNEKNKPLD---NKGEKRKRKTEEKGVDKDFESSSMKISKLEVTE---IVKPSPKR 1148
++ N L + G +KR+ E+K K + + T+ I+ PS
Sbjct: 407 RSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIE 466
Query: 1149 KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
+ T +M + ++++ S S+ ++ K S +++ ++ S + S
Sbjct: 467 SSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSK--SDKDVQSSLTHSSRDSYRSKSH 524
Query: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
Q +G R + S S + +SS G R S+ + R + E
Sbjct: 525 SQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASK----SPRKTASQLSENKPV 580
Query: 1269 NTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKY 1328
T P + ++ E+V QP+ + P VI + P + K
Sbjct: 581 KTEPLRATM----------------AQNENVV-VQPVVAENIP--VIPLSDSPPPSRWKP 621
Query: 1329 PEKESEPS-EKIQKFTKDVSHEI-IQH-----EVKSSKNSASSEKG-KTKDRDYSVLEKE 1380
+K +PS E+IQ+ +H + IQ +K + +S+S K K + D S K
Sbjct: 622 GQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKY 681
Query: 1381 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1440
+ ++S + S+ R + +S S +S H +R+ S++ + N+
Sbjct: 682 SDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASS-------HSRSRSPSSRSHSRNKYSD 734
Query: 1441 TDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNS 1500
+R S + + +R+ S K+S S +K+ E+ L K K
Sbjct: 735 HSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYV----KGRD 790
Query: 1501 SPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKH-VLEARNNKESSGNKLLYILNP 1559
S RK + +++ D +E++ +++EK +E +NK+ N
Sbjct: 791 RSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEK--------NR 842
Query: 1560 PETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVK 1619
E + + E+ K T+K LS R S R+ + + DSESN
Sbjct: 843 GEEKSKSERECPHSKKRTLKEN--LSDHLRNGSKPKRKNYAGS------KWDSESNSERD 894
Query: 1620 EEESSGNISKDLKDKIV-EKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR 1678
++S N S DK E +S + + + + S+ + P + + S+ R
Sbjct: 895 VTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQR 954
Query: 1679 SHSSSASSAESQDSKKKKKKKEKKKH-KKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSK 1737
+ S+S S +S+ + K +K KH K ++H K +++ +K +KHK K+K
Sbjct: 955 T-STSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQA 1013
Query: 1738 KNKD------KEKEKEKDDQKV 1753
+ +E+E+E DD++V
Sbjct: 1014 FHWQPPLEFGEEEEEEIDDKQV 1035
Score = 83.6 bits (205), Expect = 2e-15
Identities = 231/1243 (18%), Positives = 427/1243 (34%), Gaps = 189/1243 (15%)
Query: 599 VPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREE--FYREQRRLKEESKSPY 656
V P PP P N V TA AP +S ++ + R++K Y
Sbjct: 282 VRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRY 341
Query: 657 SGSSYSRSSYTYSKSRSGST---------RSRSYSRSFSRSHSRSYSRSPPYPRRGRGKS 707
SRS S T R R+Y S+ S P R +S
Sbjct: 342 HTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERS 401
Query: 708 RNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYRE 767
+ RSRS S+ + S + + +H + R + + + K+ Q R + R
Sbjct: 402 LSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKK---QKHCRRHKQTKKRR 458
Query: 768 VPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFS 827
+ P D+++ + + ++ER ++ S+ R+
Sbjct: 459 ILIPSDIESSKSSTRRMKSSCDRER----------------SSRSSSLSSHHSSKRDWSK 502
Query: 828 PERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKES 887
++ + S T R+ Y +S + GS+ S H ++S+ K
Sbjct: 503 SDKDV-----QSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSH-----SRSRSKSR 552
Query: 888 ENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRD 947
++ + K RK + E L + E V+ +++ V+P D
Sbjct: 553 SSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSD 612
Query: 948 DATPVRDEP--------------MDAESITFKSV-------------SEKDKRERDKPKA 980
P R +P M A++ + S +R+K
Sbjct: 613 SPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSE 672
Query: 981 KGDKTKRK-NDGSAVSKKENIVKPAKGPQEKVDGERERS-----PRSEPPIKKAKEETPK 1034
T K +D S+ S + + ++ R RS RS P ++
Sbjct: 673 SDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKY 732
Query: 1035 TDNTKSSSSS-----------------QKDEKITGTPRKAHSKSAKEHQETKPVK----- 1072
+D+++ S SS + K K HS S+++ +K VK
Sbjct: 733 SDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRS 792
Query: 1073 -------EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKD 1125
E + DYS D + + + +K + + +++ R E+ +++
Sbjct: 793 SCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERE 852
Query: 1126 FESSSMKISKLEVTEIVK--PSPKRK----MEPDTE-KMDRTPEKDKISLSAPAKKIKLN 1178
S + K +++ ++ PKRK + D+E +R K+ + S P+ +
Sbjct: 853 CPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEG 912
Query: 1179 RETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTS 1238
T I +P+ K ST++ + + K ++ T T S + + S +
Sbjct: 913 EATSDSESEVSEIHIKVKPTTK-SSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSN--SEN 969
Query: 1239 STGGSPVRKSEEKTDTKRTVIKTMEE-----YNNDNTAPAEDVIIMIQVPQSKWDKDDFE 1293
+ G K K + KR K ++E + + AP Q P +F
Sbjct: 970 NRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPL------EFG 1023
Query: 1294 SEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQH 1353
EEE+ + ++ K V +N T NI+K EK SE + T VS ++ Q
Sbjct: 1024 EEEEEEIDDKQVTQESKEKKVSENNETIKDNILK-TEKSSEEDLSGKHDTVTVSSDLDQF 1082
Query: 1354 EVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLS--Q 1411
SK S S LN + N L Q
Sbjct: 1083 TKDDSKLSISP---------------------------------TALNTEENVACLQNIQ 1109
Query: 1412 SSKEARTSDKHDSTRASSNKDF-TPNRDKKTDYDTREYSSSKRRD--EKNELTRRKDSPS 1468
+E+ + D + N + TP+R + + R D + N + ++ +
Sbjct: 1110 HVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMATE 1169
Query: 1469 RNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVD 1528
+ Q++ E + L + G DS ++ + + + A + +D
Sbjct: 1170 HPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVA------EKSQINLID 1223
Query: 1529 KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS 1588
K + L A N SS ++ + PE + + +I +K K ++ S
Sbjct: 1224 KKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRI-------EIKSKNKVRPGS 1276
Query: 1589 RLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV 1648
D R+T P ES S+ ++++S + K K++ +
Sbjct: 1277 LF--DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRS--- 1331
Query: 1649 VQVGISRNQSHSSPSVSPSRSHSPSGS-------QTRSHSSSASSAESQ--DSKKKKKKK 1699
V SR++S SS S SRS+S S S +TRS SSS S +S S+ + +
Sbjct: 1332 VSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSS 1391
Query: 1700 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDK 1742
H + + + ++ + + + + +S + +
Sbjct: 1392 SYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSR 1434
Score = 81.6 bits (200), Expect = 6e-15
Identities = 224/1130 (19%), Positives = 389/1130 (34%), Gaps = 205/1130 (18%)
Query: 649 KEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFS---RSHSRSYSRSPPYPRRGRG 705
+E S S SS+ S +SKS S ++S S +SHS+SYSR G
Sbjct: 481 RERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSR-------GSS 533
Query: 706 KSRNYRSRSRSHGYHRSRSRSPPYRRYHSR-SRSPQAFRGQSPNKRNVPQGETEREYFNR 764
+SR S+S SH RS+SRS + R S+SP+ Q + V
Sbjct: 534 RSRT-ASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQN 592
Query: 765 YREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRE 824
V P + A + D R++ ++ ++ YE+ + A
Sbjct: 593 ENVVVQP--VVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKA------------ 638
Query: 825 NFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKE 884
LP+ S ++ ++ S+ R EK S D Q +K +
Sbjct: 639 --KTTHLLPIQ---STYSLANIKETGSSSSYHKR-------EKNSESD---QSTYSKYSD 683
Query: 885 KESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR-KSREPTGVEENKTDSLFVL 943
+ SE++P + R R S + L +S +SR P+ ++
Sbjct: 684 RSSESSP-------RSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNK----- 731
Query: 944 PSRDDATPVRDEPMDAESITFKSVSEKDKRE---RDKPKAKGDKTKRKNDGSAVSKKENI 1000
D + S ++ S+S D R R + K + K S+ S+K
Sbjct: 732 --------YSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSS-SEKTLH 782
Query: 1001 VKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSK 1060
K KG + RS E++ + +++ S+Q+ EK G + H+K
Sbjct: 783 SKYVKGRDRSSCVRKYSESRSSLDYSSDSEQS----SVQATQSAQEKEK-QGQMERTHNK 837
Query: 1061 SAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK-RKRKTEE 1119
K E K E + + +K E L+ KP KN G K E
Sbjct: 838 QEKNRGEEKSKSERECPHSKKRTLK-ENLSDHLRNGSKPKRKNYA----GSKWDSESNSE 892
Query: 1120 KGVDKDFESSSMKISKLEVTEIVKPSPKR------KMEPDTEKMDRTPEKDKISLSAPAK 1173
+ V K+ ++ S S E E S K++P T+ T D + K
Sbjct: 893 RDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDD---NGAWK 949
Query: 1174 KIKLNRETGKKIGSTENISNTK-EPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLV 1232
K T GS N N + +P + + +K+E K KV+ K+ G
Sbjct: 950 SSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTK-KVKEKLKG--------- 999
Query: 1233 DYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKD-D 1291
K D K K + ++ W +
Sbjct: 1000 ------------------KKDKKHKAPKRKQAFH--------------------WQPPLE 1021
Query: 1292 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEII 1351
F EEE+ + ++ K V +N T NI+K EK SE + T VS ++
Sbjct: 1022 FGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILK-TEKSSEEDLSGKHDTVTVSSDLD 1080
Query: 1352 QHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLS- 1410
Q SK S S LN + N L
Sbjct: 1081 QFTKDDSKLSISPTA---------------------------------LNTEENVACLQN 1107
Query: 1411 -QSSKEARTSDKHDSTRASSNKDF-TPNRDKKTDYDTREYSSSKRRD--EKNELTRRKDS 1466
Q +E+ + D + N + TP+R + + R D + N + ++ +
Sbjct: 1108 IQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMA 1167
Query: 1467 PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526
+ Q++ E + L + G DS ++ + + + A +
Sbjct: 1168 TEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAE------KSQINL 1221
Query: 1527 VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH 1586
+DK + L A N SS ++ + PE + + +I +K K ++
Sbjct: 1222 IDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIE-------IKSKNKVRP 1274
Query: 1587 SSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTA 1646
S D R+T P ES S+ ++++S + K K++
Sbjct: 1275 GSLF--DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHR---- 1328
Query: 1647 AVVQVGISRNQSHSSPSVSPSRSHSPSGS-QTRSHSSSASSAESQDSKKKKKKKEKKKHK 1705
+R+ S+S S SRS S + S ++RS+S S S + + + + +K
Sbjct: 1329 -------TRSVSYSH---SRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYK 1378
Query: 1706 KHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKS 1755
H+ + + + + +S+ + + S+ ++ + +S
Sbjct: 1379 SHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRS 1428
Score = 76.6 bits (187), Expect = 2e-13
Identities = 202/1105 (18%), Positives = 395/1105 (35%), Gaps = 142/1105 (12%)
Query: 663 RSSYTYSKSRSGSTRSRSYSRSFSRS---HSRSYSRSPPYPRRGRGKSRNYRSRSRSHGY 719
R T+S+ S+ S S S S S S H RS RR + K R RS+
Sbjct: 189 RKKPTHSEGSDSSSNSSSSSESSSESELEHERS--------RRRKHKRRPKVKRSKKRRK 240
Query: 720 HRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYG 779
S S P R H+ + + R + KR+V + R E+PP + +
Sbjct: 241 EASSSEEP--RNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLR 298
Query: 780 RSVDFRD-----------PFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSP 828
R + P ++ + R+ + Y + R + ++
Sbjct: 299 RDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358
Query: 829 ERFLPLNIRNSPFTRGRR----EDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKE 884
P R R E + G S S + E+ ++ + N +
Sbjct: 359 SETPPHWKEEMQRLRAYRPPSGEKWSKGDK-LSDPCSSRWDERSLSQRSRSWSYNGYYSD 417
Query: 885 KESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLP 944
+ G K + +K K +K + + R+ P+ +E +K+ + +
Sbjct: 418 LSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKS 477
Query: 945 SRDDATPVRDEPMDAESITFKSVSEKDKR-ERDKPKAKGDKTKRKNDGSAVSKKENIVKP 1003
S D R + + + + S+ DK + + D + K+ + S+ + +
Sbjct: 478 SCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRT 537
Query: 1004 AKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAK 1063
A K+ + ++SSS S ++ + +PR K+A
Sbjct: 538 A---------------------SKSSSHSRSRSKSRSSSKSGHRKRASKSPR----KTAS 572
Query: 1064 EHQETKPVKEEKVKKDYSKD-------VKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK 1116
+ E KPVK E ++ +++ V +E + P + KP G+K +
Sbjct: 573 QLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKP----GQKPWKP 628
Query: 1117 TEEKGVDKDFES-------SSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS 1169
+ E+ + ++ S+ ++ ++ T KR+ ++++ + D+ S S
Sbjct: 629 SYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSES 688
Query: 1170 APAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSS 1229
+P + + +R + + S + S L S+ S+ + + R K + S
Sbjct: 689 SPRSRSRSSR--------SRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYS-DHSQCS 739
Query: 1230 TLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDV------IIMIQVP 1283
YTS SS G ++ + K +V +++ T ++ V + +
Sbjct: 740 RSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYS 799
Query: 1284 QSKWDKD-DFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKF 1342
+S+ D +SE+ V++TQ K + + + + N + EK E
Sbjct: 800 ESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKN--RGEEKSKSERECPHSK 857
Query: 1343 TKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNE 1402
+ + + H SK + G D + S E++ + KN + P + E
Sbjct: 858 KRTLKENLSDHLRNGSKPKRKNYAGSKWDSE-SNSERDVTKNSKNDSHPSSD------KE 910
Query: 1403 QGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRR----DEKN 1458
+G S S+S +T++S+N D + SSK+R D +
Sbjct: 911 EGEATSDSESEVSEIHIKVKPTTKSSTNTSLPD--------DNGAWKSSKQRTSTSDSEG 962
Query: 1459 ELTRRKDSPSRNKDSASGQKNKPREE--RDLPKKGTGDSKKSNSSPSRDRKPH------- 1509
+ +++ + + G K + E + + +K G K + +P R + H
Sbjct: 963 SCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEF 1022
Query: 1510 --DHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKE 1567
+ + D K+ +E+K +K ++ E ++SS L + + +
Sbjct: 1023 GEEEEEEIDDKQVTQESK--EKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLD 1080
Query: 1568 QITGQIDKSTVKPKPQ--------LSHSSRLSSDLTRETDEAAFEPDYNE---SDSESNV 1616
Q T K ++ P L + + + ++ D E D S
Sbjct: 1081 QFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPA 1140
Query: 1617 SVKEEESSGNISKDLKD-KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGS 1675
V+E GN D D IV K + + Q + + +S S+S S+ G
Sbjct: 1141 KVEETSPLGNARLDTPDINIVLKQDMATEHP---QAEVVKQES----SMSESKVLGEVGK 1193
Query: 1676 QTRSHSSSASSAESQDSKKKKKKKE 1700
Q S +S AS+ ES K+ +K +
Sbjct: 1194 QDSSSASLASAGESTGKKEVAEKSQ 1218
Score = 43.1 bits (100), Expect = 0.002
Identities = 77/347 (22%), Positives = 131/347 (37%), Gaps = 51/347 (14%)
Query: 1407 KSLSQSSKEARTSDKH-DSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD 1465
KS+ ++ R H + + +SSN + +++ E+ S+RR K + K
Sbjct: 179 KSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESEL---EHERSRRRKHKRR-PKVKR 234
Query: 1466 SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETK 1525
S R K+++S ++ PR + + KG + +N E +
Sbjct: 235 SKKRRKEASSSEE--PRNKHAMNPKGHSERSDTN-----------------------EKR 269
Query: 1526 SVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLS 1585
SVD + REK V+ N+ L + P E E + KP +S
Sbjct: 270 SVDSSA--KREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVS 327
Query: 1586 HSSRLSSDL------TRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKA 1639
S R T + E D ++S SE+ KEE + + K
Sbjct: 328 KSGRKIKGRGTIRYHTPPRSRSCSESDDDDS-SETPPHWKEEMQRLRAYRPPSGEKWSKG 386
Query: 1640 KESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKK- 1698
+ D + SR S RS S S + S S+A + ++K+KK
Sbjct: 387 DKLSDPCS------SRWDERSLSQ----RSRSWSYNGYYSDLSTARHSGHHKKRRKEKKV 436
Query: 1699 KEKKKHKKHKKHKKHKKHAGTEVELEKS-QKHKHKKKKSKKNKDKEK 1744
K KKK KK K ++HK+ + + + K ++ K + D+E+
Sbjct: 437 KHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRER 483
Score = 32.7 bits (73), Expect = 3.2
Identities = 15/62 (24%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 1691 DSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKK-KSKKNKDKEKEKEKD 1749
+ K+KK + + + +E+E E+S++ KHK++ K K++K + KE
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSS 245
Query: 1750 DQ 1751
++
Sbjct: 246 EE 247
Score = 32.0 bits (71), Expect = 5.5
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 617 SSGVQTAHSNTIPTTQAPPLSREEFYREQRRLK--EESKSPYSGSSYSRSSYTYSKSRSG 674
SS ++ S+ P +++ + + +Y R + S S + G SY+R S + S
Sbjct: 1383 SSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSD 1442
Query: 675 STRSRSYSRSFSRSHSRSYS 694
S RSYS S S S YS
Sbjct: 1443 SESDRSYSHHRSPSESSRYS 1462
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 101 bits (251), Expect = 7e-21
Identities = 135/602 (22%), Positives = 230/602 (38%), Gaps = 89/602 (14%)
Query: 1176 KLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTG--TEGSSSTLVD 1233
K +ET TE T+E +E+ E + + + ++ +G + G E S +
Sbjct: 449 KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 1234 YTSTSSTGGSPVR---------KSEEKTDTKRTV-IKTMEEYNNDNTAPAEDVIIMIQVP 1283
S SPV+ KS EK + K +K+ E+ + PA++
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS----PAKE-------- 556
Query: 1284 QSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFT 1343
++K + E+E+ KS + S K S K + P+ K PEK P
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE-AKSPEKAKSP-------- 607
Query: 1344 KDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQ 1403
VK S + K K+ S E ++PEK K+ T+ E +S
Sbjct: 608 -----------VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE------ 650
Query: 1404 GNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDK---KTDYDTREYSSSKRRDEKNEL 1460
K+ S +EA++ +K S + K +P + K K + + E + S ++E
Sbjct: 651 ---KAKSPEKEEAKSPEKAKSPVKAEAK--SPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 1461 TRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRP 1520
+ K S K+ +EE P+K K+ SP + + P K T D K P
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK-TLDVKSP 764
Query: 1521 NEETKS-------VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQI 1573
+T + DK P K + V E + E + + L PE ++ K++
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSP-VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV--- 820
Query: 1574 DKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1633
KS VK + + E ++A P E ++E+ ++ K+
Sbjct: 821 -KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879
Query: 1634 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSK 1693
VEK KES +V + ++ V +P+ + + +D+K
Sbjct: 880 PAVEKPKES-------KVEAKKEEAEDKKKVPTPEKEAPAKVEVK-----------EDAK 921
Query: 1694 KKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKV 1753
K+K + KK K K+ K A + + + K +K K + K K + K K+D K
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 1754 KS 1755
S
Sbjct: 982 LS 983
Score = 90.9 bits (224), Expect = 1e-17
Identities = 110/453 (24%), Positives = 174/453 (38%), Gaps = 48/453 (10%)
Query: 865 PEKLSARDGHNQK--DNTKSKEKESENAPGDGKG--------NKHKKHRKRRKGEESEGF 914
PEK A+ K + KS KE +P + K + K K E
Sbjct: 567 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Query: 915 LNPELLETSRKSREPTGVEENKTDSLFVLPSRDDA-------TPVRDEPMDAESITFKSV 967
+P +++ K++ PT EE K+ P +++A +PV+ E E
Sbjct: 627 KSPAEVKSPEKAKSPTK-EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685
Query: 968 SEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGP--QEKVDGERERSPRSEP-- 1023
+E E+ K K + + S V ++ + AK P +E E+ +SP E
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745
Query: 1024 -PIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSK 1082
P K E KT + KS + ++ +P + AK + + EK K +
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 1083 DVKS-EKLTTKEEKAKKP-NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVT- 1139
D K+ EK K+E+ K P E+ KP + K ++ +K EE+ ++ K SK E
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 1140 --EIVKPSPKRKMEPDTE---------KMDRTPEKDKI---SLSAPAK-------KIKLN 1178
E KP + K EP E K + +K K+ APAK K K
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK 925
Query: 1179 RETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTS 1238
E KK +P+EK E+ K ++ K K + TE + D T +
Sbjct: 926 TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE-DDKTLSK 984
Query: 1239 STGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTA 1271
K+E+ + T + K E+ D A
Sbjct: 985 EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 89.4 bits (220), Expect = 3e-17
Identities = 140/633 (22%), Positives = 243/633 (38%), Gaps = 79/633 (12%)
Query: 601 PPGFPPAPANLSTPWVSSG-----VQTAHSNTI---PTTQAPPLSREEFYREQRRLKEES 652
P G P P+ + V S V+ + T+ T+ ++ E E++ KEE
Sbjct: 423 PEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEE 482
Query: 653 KSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRS 712
G + +++S + ++S + ++SP
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP--------------- 527
Query: 713 RSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPY 772
+ + + ++SP + +++SP +SP + P E+E EV P
Sbjct: 528 -AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP----EKEEAKSPAEVKSPE 582
Query: 773 DMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAG-AQPRPSANRENFSPERF 831
K+ P ++E E K E + K A A+ + E SP
Sbjct: 583 KAKS----------PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 832 LPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAP 891
SP +E+ + +S PEK A+ K K++ K E A
Sbjct: 633 KSPEKAKSP----TKEEAKSPEKAKS-------PEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 892 GDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDA-T 950
K K ++ K E +PE K++ P EE K+ P +++A T
Sbjct: 682 SPVKAEA--KSPEKAKSPVKEEAKSPE------KAKSPVK-EEAKSPEKAKSPVKEEAKT 732
Query: 951 PVRDE-PMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGP-- 1007
P + + P+ E+ + + +K + K+ KT K + A S + + AK P
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE--ARSPADKFPEKAKSPVK 790
Query: 1008 QEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK---DEKITGTPRKAHSKSAKE 1064
+E E+ +SP E K ++E PK + KS ++ + K+ P+KA + A
Sbjct: 791 EEVKSPEKAKSPLKEDA-KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 1065 HQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDK 1124
+T+ K+ K ++ K+ K+ K+E A + KP ++K E +K + E+K
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE-----KPKESKVEAKKEEAEDKKKVP 904
Query: 1125 DFESSSMKISKLEVTEIVKPSPKR---KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRET 1181
E + +K+EV E KP K K EPD K + + +AP KK +
Sbjct: 905 TPEKEAP--AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962
Query: 1182 GKKIGSTENISNTKEPSEKLESTSSKVKQEKVK 1214
K + + KE + L SK K EK +
Sbjct: 963 KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Score = 84.7 bits (208), Expect = 7e-16
Identities = 101/460 (21%), Positives = 201/460 (43%), Gaps = 36/460 (7%)
Query: 1310 KPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKD--VSHEIIQHEVKSSKNSASSEK- 1366
K SV ++ K +K EK + + +++ T++ V+ E+ + E K +K E+
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 1367 -GKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST 1425
G+ ++ + E ++P + + PEKE+ + K ++S EA++ +K ++
Sbjct: 488 GGEEEEAEGGEEETKSPPAEE-AASPEKEA-------KSPVKEEAKSPAEAKSPEKEEAK 539
Query: 1426 RASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD--SPSRNKDSASGQKNKPRE 1483
+ K +P + K + + + EK E + SP + K A + P E
Sbjct: 540 SPAEVK--SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 1484 ERDLPKKGTGDSKKSNSSPSRDRKP--HDHKATYDTKRPNE---ETKSVDKNPCKDREKH 1538
+ P+K K+ SP+ + P + K+ + K P + TK K+P K +
Sbjct: 598 AKS-PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 1539 VLEARNNKESSGNKLLYILNPPETQ--VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTR 1596
EA++ +++ +P + + V+ E + + KS VK + + ++
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 1597 ETDEAAFEPDYNESDS--ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGIS 1654
++ E A P E+ + ++ VKEE S K K EKAK +LD + +
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE-----KAKSPEKAK-TLDVKSPEAKTPA 770
Query: 1655 RNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHK 1714
+ ++ S P ++ SP + +S A S +D+K +K+ KK+ K ++ K
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKS-PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 1715 KHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754
EV++++ K ++K K +EK+ K ++ K
Sbjct: 830 PQ---EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866
Score = 80.9 bits (198), Expect = 1e-14
Identities = 138/661 (20%), Positives = 252/661 (38%), Gaps = 111/661 (16%)
Query: 995 SKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTP 1054
S+KE ++ + + +V E +E K+AKEE K + ++ E+ T +P
Sbjct: 450 SEKETVIVEEQTEETQVTEEV-----TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP 504
Query: 1055 RKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG---E 1111
A ++ E + PVKEE +E + ++E+AK P E P K E
Sbjct: 505 -PAEEAASPEKEAKSPVKEEAKSP-------AEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 1112 KRKRKTEEKGVDKDFESSSMKISKLEVTEI-VKPSPKRKMEPDTEKMDRTPEKDKISLSA 1170
+ K E K +K+ S ++ E + K K E + + ++P K++ A
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616
Query: 1171 PAKK-IKLNRETGKKIGSTENI-SNTKEPSEKLESTSSKVKQE-----KVKGKVRRKVTG 1223
AK +K ++ ++ S E S TKE ++ E S K+E K K V+ +
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676
Query: 1224 TEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVP 1283
E + S + + SPV++ + + ++ +K + +P ++
Sbjct: 677 PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE-------- 728
Query: 1284 QSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKES--EPSEKIQK 1341
++K + +E+ KS + S K K + K S K P KE P++K +
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKA----KTLDVK-SPEAKTPAKEEARSPADKFPE 783
Query: 1342 FTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLN 1401
K ++ EVKS + + S K D EKE P+K + + ++E
Sbjct: 784 KAKSP----VKEEVKSPEKAKSPLK-----EDAKAPEKEIPKKEEVKSPVKEEEK----- 829
Query: 1402 EQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELT 1461
Q K K + +A + TP ++K +D K E
Sbjct: 830 --------PQEVKVKEPPKKAEEEKAPA----TPKTEEK-------------KDSKKEEA 864
Query: 1462 RRKDSPS-RNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRP 1520
+K++P + ++ KP+E + KK + KK +P ++
Sbjct: 865 PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP------------- 911
Query: 1521 NEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKP 1580
K K K +EK + + ++ + P EK++ +K K
Sbjct: 912 ---AKVEVKEDAKPKEKTEVAKKEPDDAKAKE-------PSKPAEKKEAAP--EKKDTKE 959
Query: 1581 KPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK 1640
+ + ++ + D+ + ++ +E K E+SS KD K EKA
Sbjct: 960 EKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE-----KAEKSSSTDQKDSKPP--EKAT 1012
Query: 1641 E 1641
E
Sbjct: 1013 E 1013
Score = 59.7 bits (143), Expect = 2e-08
Identities = 73/316 (23%), Positives = 133/316 (42%), Gaps = 24/316 (7%)
Query: 1455 DEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKAT 1514
+E+ E T+ + + ++ + ++ EE ++ G +++ S P+ + + +A
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 1515 YDTKRPNEETKSVD--KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQV-EKEQITG 1571
K EE KS K+P K+ K E ++ +++ +PPE + EKE+
Sbjct: 518 SPVK---EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 1572 QID-KSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDS--ESNVSVKEEESSGNIS 1628
+ KS K K ++ S ++ E A P E+ S E+ VKEE S
Sbjct: 575 PAEVKSPEKAKSPAKEEAK--SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS---- 628
Query: 1629 KDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSAS--- 1685
+ K EKAK T + + SP ++ SP ++ +S + S
Sbjct: 629 -PAEVKSPEKAKSP--TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685
Query: 1686 -SAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVE--LEKSQKHKHKKKKSKKNKDK 1742
A+S + K K+E K +K K K + + + + +++ K K K K + K
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745
Query: 1743 EKEKEKDDQKVKSVTV 1758
EK K +K K++ V
Sbjct: 746 SPEKAKSPEKAKTLDV 761
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 99.8 bits (247), Expect = 2e-20
Identities = 197/968 (20%), Positives = 382/968 (39%), Gaps = 151/968 (15%)
Query: 855 HRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGF 914
H S + G KL R G N K E+ + A + K R+ ++ E +
Sbjct: 233 HDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLK--REVPLSDDDESY 290
Query: 915 LNPELLETSRKSREPTGVEEN-----KTDSLF-----VLPSRDDATPVRDE----PMDAE 960
+ E +S P+ V+EN + DSL +LPS+ DE D E
Sbjct: 291 TDSE----EAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDE 346
Query: 961 SITF----KSVSEKDKRERDKPKAKGDKTKRKNDGSAVSK--KENIVKPAKGPQEKVDGE 1014
I + + K++R+ ++P+A+ K + + K K KP++ +
Sbjct: 347 EINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESS 406
Query: 1015 RERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEE 1074
E + +++ I + P+T N S ++K+ ++G EH++ VK +
Sbjct: 407 DEEALQNKK-ISTSCSVIPETSN--SDMQTKKEYVVSG-----------EHKQKGKVKRK 452
Query: 1075 KVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLD-NKGEKRKRKTEEKG-VDKDF------ 1126
K+ +K+ ++++L K+EK K N + L N G KT E+G K F
Sbjct: 453 L--KNQNKNKENQEL--KQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDT 508
Query: 1127 --------------------ESSSMKISKLEVTEIVKP-SPKRKMEPDTEKMDRT----- 1160
E S + + + P S + ++PD + D T
Sbjct: 509 SLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFL 568
Query: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENIS-NTKEPSEKLESTSSKVKQEKVKGKVRR 1219
PE + +K K ++ + G N ++ S E++ +K+ +GK +
Sbjct: 569 PESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLK 628
Query: 1220 KVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIM 1279
K K EK K+ + E+Y ++A +++
Sbjct: 629 K---------------------HKLKHKEREKEKHKKEIEGEKEKYKTKDSA--KELQRS 665
Query: 1280 IQVPQSKWDKDDFESEEED---VKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS 1336
++ + W ++ F+S+E + + ++ K + + KN+ S K+ KE
Sbjct: 666 VEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFK 725
Query: 1337 EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESN 1396
E+ K K+ + ++K K + KD +++ L E+ EKE +
Sbjct: 726 EERDKIKKESEKSFREEKIKDLKEERENIP-TDKDSEFTSLGMSAIEESIGLHLVEKEID 784
Query: 1397 LDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDE 1456
+++ ++ + K S+ E R+ K K F ++KK + E+ S K +
Sbjct: 785 IEK--QEKHIKE-SKEKPEKRSQIKEKDIEKMERKTF--EKEKKIKH---EHKSEK---D 833
Query: 1457 KNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYD 1516
K +L+ D S K +E + K K + SR++ H D
Sbjct: 834 KLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKH----D 889
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS 1576
++P +E ++ + +EKH++E + NK+S ++ Y + EK++ + +KS
Sbjct: 890 KEKPEKE-----RHLAESKEKHLME-KKNKQSDNSE--YSKSEKGKNKEKDRELDKKEKS 941
Query: 1577 TVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNIS------KD 1630
K +++S + + ++ + D N++ E +S+KE+ + KD
Sbjct: 942 RDKESINITNSKHI------QEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKD 995
Query: 1631 LKDKIVEKAKESLDTAAVVQVG----ISRNQSHSSPSVSP-SRSHSPSGSQTRSHSSSAS 1685
KDK +++ KE +Q+ + P SP S+ P + + +
Sbjct: 996 KKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQT 1055
Query: 1686 SAESQDSKKKKKKKE-KKKHKKHKKHKKHKKHAG---TEVELEKSQKHKHKKKKSKKNKD 1741
S E S K + ++ KKHK+ K K+ ++ E++++ +K KH +S KNK+
Sbjct: 1056 SFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTES-KNKE 1114
Query: 1742 KEKEKEKD 1749
+ K +
Sbjct: 1115 LTRSKSSE 1122
Score = 97.8 bits (242), Expect = 8e-20
Identities = 179/882 (20%), Positives = 350/882 (39%), Gaps = 94/882 (10%)
Query: 883 KEKESENAPGDGKGNKHKKHRKR--RKGEESEGFLNPELLETSRKSREPTGVEENK-TDS 939
KE+ EN P K + K K K +S+ +L +S +S + ++ K + S
Sbjct: 360 KEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTS 419
Query: 940 LFVLP--SRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKK 997
V+P S D ++ + E V K K + + + K++ +G ++
Sbjct: 420 CSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKE--NQELKQEKEGKENTRI 477
Query: 998 ENI-----VKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITG 1052
N+ + ++ +E+ + + SP+ + + T K+ S ++ +
Sbjct: 478 TNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQ 537
Query: 1053 TPRKAHSKSAKEHQETKP--VKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG 1110
K +P V+ + + ++ + S K +EK+K ++K+ L+ G
Sbjct: 538 EHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSK--HQKDFHLEF-G 594
Query: 1111 EKRKRKTEEKGVDKDFESSSMKISKL--EVTEIVKPSPKRK-MEPDTEKMDRTPEKDKIS 1167
EK K +++ FE+S + K+ E + K K K E + K + EK+K
Sbjct: 595 EKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYK 654
Query: 1168 LSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGS 1227
AK+++ + E ++ EN + E + + + + K K+ + + + +
Sbjct: 655 TKDSAKELQRSVEFDREFWK-ENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKST 713
Query: 1228 SSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKW 1287
V ++K EK+ + + EE N T S++
Sbjct: 714 KEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDK-----------DSEF 762
Query: 1288 DKDDFESEEEDV--KSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKD 1345
+ EE + + + K IK KP + EK+ E E+ + F K+
Sbjct: 763 TSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMER-KTFEKE 821
Query: 1346 VSHEIIQHEVKSSKN----SASSEKGKTKDRDYSV-LEK--ENPEKRKNSTQPEKESNLD 1398
I+HE KS K+ S +K K KD+ YS EK + EK KN+ +K + +
Sbjct: 822 KK---IKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE 878
Query: 1399 RLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKR-RDEK 1457
+ E+ + K KE ++H S K ++K++D EYS S++ ++++
Sbjct: 879 KSREKMDRKH----DKEKPEKERH--LAESKEKHLMEKKNKQSD--NSEYSKSEKGKNKE 930
Query: 1458 NELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKA-TYD 1516
+ K SR+K+S + +K +E G+ + S K D T D
Sbjct: 931 KDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPD 990
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS 1576
K +++ K +D+ +D+ K ++ N LL + + +
Sbjct: 991 GKEKDKKDKDIDRYKERDKHKDKIQI--------NSLLKLKSEAD--------------- 1027
Query: 1577 TVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIV 1636
KPKP+ SS S D TR ++ D ++ E +S+K+ E K K+KI
Sbjct: 1028 --KPKPK---SSPASKD-TRPKEKRLVNDDLMQTSFERMLSLKDLEIE-QWHKKHKEKIK 1080
Query: 1637 EKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK 1696
+K KE L +++ I + H+P+ S+ + + S SS + K+K
Sbjct: 1081 QKEKERLRNRNCLELKIKDKEK---------TKHTPTESKNKELTRSKSSEVTDAYTKEK 1131
Query: 1697 KKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK 1738
+ K+ ++ K+ G + + ++ + +++K
Sbjct: 1132 QPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENEK 1173
Score = 67.8 bits (164), Expect = 9e-11
Identities = 194/977 (19%), Positives = 349/977 (35%), Gaps = 147/977 (15%)
Query: 882 SKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLF 941
+K +SEN+ D N +K R+ ++ + +E S S+E K F
Sbjct: 7 TKPIQSENSDSDS--NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPF 64
Query: 942 VLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIV 1001
+ +P R+E D S+ +K +K K K + +K+ ++ +
Sbjct: 65 TI------SPSRNEERD---------SDTEKEGPEKKKTKKEAGNKKSTPVSILFGYPLS 109
Query: 1002 KPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPR-KAHSK 1060
+ + R+ SP S P + TP T SSSS QKD+ R +
Sbjct: 110 ERKQMALLMQMTARDNSPDSTP--NHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLH 167
Query: 1061 SAKEHQETKPVKE------EKVKKDYS-------------KDVKSEKLTTKEEKAKKPNE 1101
A + K VKE KD++ DV + + + +
Sbjct: 168 MAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLD 227
Query: 1102 KNKPLDNKGEKRKR---KTEEKGVDKDFESSSMKISKLEV--TEIVKPSPKRK--MEPDT 1154
+ PL + R K + F+++ ++V TE ++ KR+ + D
Sbjct: 228 DDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSDDD 287
Query: 1155 EKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEP-----------SEKLES 1203
E + E ++ S+ + I E I ++ I +K P + E
Sbjct: 288 ESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEE 347
Query: 1204 TSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTME 1263
+ + + K +RK E + L + P +K R + + E
Sbjct: 348 INKMIDDRHILRKEQRKENEPEAEKTHLF---AKQEKAFYPKSFKSKKQKPSRVLYSSTE 404
Query: 1264 EYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1323
+ + + +P++ D ++++E V S + GK +KN +
Sbjct: 405 SSDEEALQNKKISTSCSVIPET--SNSDMQTKKEYVVSGEH-KQKGKVKRKLKNQNKNKE 461
Query: 1324 NIVKYPEKESEPSEKIQKFT-----------------------KDVSHEIIQH--EVKSS 1358
N EKE + + +I T KD + + H KS
Sbjct: 462 NQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSP 521
Query: 1359 KNSAS-SEKGKTKDRDYSVLEKENPEKRKNSTQPE----KESNLDRLNEQGNFKSLSQSS 1413
K+S SEK T + +P + S QP+ + + L E + KS
Sbjct: 522 KHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKE 581
Query: 1414 KEARTSDKHDSTRASSN-----KDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS 1468
K D H SN +D +P + +D ++ + +K++L ++
Sbjct: 582 KSKHQKDFHLEFGEKSNAKIKDEDHSPTFE-NSDCTLKKMDKEGKTLKKHKLKHKEREKE 640
Query: 1469 RNKDSASGQKNKPREE---RDLPKKGTGDSK-------KSNSSPSRDRKPHDHKATYDTK 1518
++K G+K K + + ++L + D + KS+ + T + K
Sbjct: 641 KHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKK 700
Query: 1519 RPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTV 1578
E+ DK+ +EKHV + RN KE I E +E+I ++
Sbjct: 701 SKLEKNIKDDKS---TKEKHVSKERNFKEERDK----IKKESEKSFREEKIKDLKEEREN 753
Query: 1579 KPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVS-VKEEESSGNISKDLKDKIVE 1637
P + S + L E+ E D E +KE + +K+K +E
Sbjct: 754 IPTDKDSEFTSLGMSAIEES--IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIE 811
Query: 1638 K------------------AKESLDTAAVVQVGISRNQ--SHSSPSVSPSRSHSPSGSQT 1677
K K+ LD + V +++ SH + S + +
Sbjct: 812 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAI 871
Query: 1678 RSHSSSASSAESQDSKKKKKKKEKKKH-----KKHKKHKKHKKHAGTEVELEKSQKHKHK 1732
+ S E D K K+K EK++H +KH KK+K+ + E KS+K K+K
Sbjct: 872 KKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNS--EYSKSEKGKNK 929
Query: 1733 KKKSKKNKDKEKEKEKD 1749
+K + +K KEK ++K+
Sbjct: 930 EKDRELDK-KEKSRDKE 945
Score = 64.7 bits (156), Expect = 8e-10
Identities = 119/563 (21%), Positives = 210/563 (37%), Gaps = 117/563 (20%)
Query: 790 KERYREWERKYREWYEKYYKGYAAGAQPRPSANREN-FSPERFLPLNIRNSPFTRGRRED 848
KER +E +K E ++ YK + + + S + F E F F ED
Sbjct: 635 KEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENF---------FKSDETED 685
Query: 849 YVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKG 908
H S + EK S + N KD+ +KEK K K+ R + K
Sbjct: 686 LFLNMEHESLTL-----EKKSKLE-KNIKDDKSTKEKHVS------KERNFKEERDKIK- 732
Query: 909 EESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVS 968
+ESE E ++ ++ RE +++ + + + +++ + + + I +
Sbjct: 733 KESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLH---LVEKEIDIEKQE 789
Query: 969 EKDKRERDKPKAKG---DKTKRKNDGSAVSKKENIVKPAKGPQEK------VDGERERSP 1019
+ K ++KP+ + +K K + K++ I K ++K VD +E+
Sbjct: 790 KHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDK 849
Query: 1020 RSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKD 1079
+K +E K+ NT + + EK + K ++H + KP KE + +
Sbjct: 850 LYSHHTEKCHKEGEKSKNTAAIKKTDDREK-------SREKMDRKHDKEKPEKERHLAES 902
Query: 1080 YSKDV--KSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK--------TEEKGVDKDFESS 1129
K + K K + E +K KNK D + +K+++ T K + ++ +SS
Sbjct: 903 KEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSS 962
Query: 1130 SMKISK------LEVTEIVKPSP--------KRKMEPDTEK-MDRTPEKDKISLSAPAKK 1174
+ +K L + E K P K K + D ++ +R KDKI +++
Sbjct: 963 IVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINS---L 1019
Query: 1175 IKLNRETGKKIGSTENISNTKEPSEK------LESTS--------------------SKV 1208
+KL E K + S P EK L TS K+
Sbjct: 1020 LKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKI 1079
Query: 1209 KQE-------------KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGG--------SPVRK 1247
KQ+ K+K K + K T TE + L S+ T V
Sbjct: 1080 KQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN 1139
Query: 1248 SEEKTDTKRTVIKTMEEYNNDNT 1270
+ DTK + + +DN+
Sbjct: 1140 RSQSVDTKNVMTLGKSSFVSDNS 1162
Score = 57.0 bits (136), Expect = 2e-07
Identities = 143/766 (18%), Positives = 282/766 (36%), Gaps = 111/766 (14%)
Query: 1077 KKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKL 1136
K ++K ++SE + +KP + + K E V K+ + S KL
Sbjct: 3 KSGFTKPIQSENSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKL 62
Query: 1137 EVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKK------------------IKLN 1178
T SP R E D++ PEK K A KK L
Sbjct: 63 PFTI----SPSRNEERDSDTEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLM 118
Query: 1179 RETGK--KIGSTENISNTKEPSEKLESTSSKVKQEKV-----KGKVRRKVTGTEGSSSTL 1231
+ T + ST N + P++K +SS +++KV +G+ + G +
Sbjct: 119 QMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQV 178
Query: 1232 VDYTSTSS-------TGGSPVRK--SEEKTDTKRTVIKTMEEYNN---DNTAPAED---- 1275
+ S + G +P+ + + D + +I + N D+ P D
Sbjct: 179 KELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASS 238
Query: 1276 -----VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKN-----------VS 1319
V ++++ + + + DV T+ + + K + + S
Sbjct: 239 GHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQS 298
Query: 1320 TKPSNIVKYPEKESE------PSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRD 1373
PS++ + + E+E S++I + + ++E K + E K D D
Sbjct: 299 VNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDD---EEINKMID-D 354
Query: 1374 YSVLEKENPEKRKNSTQPEKE---SNLDRLNEQGNFKSLSQ-------SSKEARTSDKHD 1423
+L KE ++++N + EK + ++ +FKS Q SS E+ +
Sbjct: 355 RHILRKE--QRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQ 412
Query: 1424 STRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPRE 1483
+ + S++ P +EY S +K ++ R+ + ++NK++ ++ K +
Sbjct: 413 NKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGK 472
Query: 1484 ERDLPKKGTGDSKKSNSSPSRD----RKPHDHKATYDTKRPNEETKSVDKNPC--KDREK 1537
E T ++ S +R+ RK K + T K+ C +++
Sbjct: 473 ENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQS 532
Query: 1538 HVLEARNNKE--SSGNKLLYILNPPETQVEKEQITGQIDKSTVKP---KPQLSHSSRLSS 1592
L+ + K S G+ + L P + + + + S+VK K + H
Sbjct: 533 TPLKQEHTKTCLSPGSSEM-SLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHL 591
Query: 1593 DLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVG 1652
+ +++ + D++ + S+ ++K+ + G K K K E+ KE
Sbjct: 592 EFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIE---- 647
Query: 1653 ISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQD----------SKKKKKKKEKK 1702
+ + + + S + + S E++D + +KK K EK
Sbjct: 648 -GEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKN 706
Query: 1703 -KHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKE 1747
K K K K K + E +K +K K + +K KD ++E+E
Sbjct: 707 IKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERE 752
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 99.8 bits (247), Expect = 2e-20
Identities = 197/968 (20%), Positives = 382/968 (39%), Gaps = 151/968 (15%)
Query: 855 HRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGF 914
H S + G KL R G N K E+ + A + K R+ ++ E +
Sbjct: 256 HDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLK--REVPLSDDDESY 313
Query: 915 LNPELLETSRKSREPTGVEEN-----KTDSLF-----VLPSRDDATPVRDE----PMDAE 960
+ E +S P+ V+EN + DSL +LPS+ DE D E
Sbjct: 314 TDSE----EAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDE 369
Query: 961 SITF----KSVSEKDKRERDKPKAKGDKTKRKNDGSAVSK--KENIVKPAKGPQEKVDGE 1014
I + + K++R+ ++P+A+ K + + K K KP++ +
Sbjct: 370 EINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESS 429
Query: 1015 RERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEE 1074
E + +++ I + P+T N S ++K+ ++G EH++ VK +
Sbjct: 430 DEEALQNKK-ISTSCSVIPETSN--SDMQTKKEYVVSG-----------EHKQKGKVKRK 475
Query: 1075 KVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLD-NKGEKRKRKTEEKG-VDKDF------ 1126
K+ +K+ ++++L K+EK K N + L N G KT E+G K F
Sbjct: 476 L--KNQNKNKENQEL--KQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDT 531
Query: 1127 --------------------ESSSMKISKLEVTEIVKP-SPKRKMEPDTEKMDRT----- 1160
E S + + + P S + ++PD + D T
Sbjct: 532 SLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFL 591
Query: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENIS-NTKEPSEKLESTSSKVKQEKVKGKVRR 1219
PE + +K K ++ + G N ++ S E++ +K+ +GK +
Sbjct: 592 PESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLK 651
Query: 1220 KVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIM 1279
K K EK K+ + E+Y ++A +++
Sbjct: 652 K---------------------HKLKHKEREKEKHKKEIEGEKEKYKTKDSA--KELQRS 688
Query: 1280 IQVPQSKWDKDDFESEEED---VKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS 1336
++ + W ++ F+S+E + + ++ K + + KN+ S K+ KE
Sbjct: 689 VEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFK 748
Query: 1337 EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESN 1396
E+ K K+ + ++K K + KD +++ L E+ EKE +
Sbjct: 749 EERDKIKKESEKSFREEKIKDLKEERENIP-TDKDSEFTSLGMSAIEESIGLHLVEKEID 807
Query: 1397 LDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDE 1456
+++ ++ + K S+ E R+ K K F ++KK + E+ S K +
Sbjct: 808 IEK--QEKHIKE-SKEKPEKRSQIKEKDIEKMERKTF--EKEKKIKH---EHKSEK---D 856
Query: 1457 KNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYD 1516
K +L+ D S K +E + K K + SR++ H D
Sbjct: 857 KLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKH----D 912
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS 1576
++P +E ++ + +EKH++E + NK+S ++ Y + EK++ + +KS
Sbjct: 913 KEKPEKE-----RHLAESKEKHLME-KKNKQSDNSE--YSKSEKGKNKEKDRELDKKEKS 964
Query: 1577 TVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNIS------KD 1630
K +++S + + ++ + D N++ E +S+KE+ + KD
Sbjct: 965 RDKESINITNSKHI------QEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKD 1018
Query: 1631 LKDKIVEKAKESLDTAAVVQVG----ISRNQSHSSPSVSP-SRSHSPSGSQTRSHSSSAS 1685
KDK +++ KE +Q+ + P SP S+ P + + +
Sbjct: 1019 KKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQT 1078
Query: 1686 SAESQDSKKKKKKKE-KKKHKKHKKHKKHKKHAG---TEVELEKSQKHKHKKKKSKKNKD 1741
S E S K + ++ KKHK+ K K+ ++ E++++ +K KH +S KNK+
Sbjct: 1079 SFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTES-KNKE 1137
Query: 1742 KEKEKEKD 1749
+ K +
Sbjct: 1138 LTRSKSSE 1145
Score = 97.8 bits (242), Expect = 8e-20
Identities = 179/882 (20%), Positives = 350/882 (39%), Gaps = 94/882 (10%)
Query: 883 KEKESENAPGDGKGNKHKKHRKR--RKGEESEGFLNPELLETSRKSREPTGVEENK-TDS 939
KE+ EN P K + K K K +S+ +L +S +S + ++ K + S
Sbjct: 383 KEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTS 442
Query: 940 LFVLP--SRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKK 997
V+P S D ++ + E V K K + + + K++ +G ++
Sbjct: 443 CSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKE--NQELKQEKEGKENTRI 500
Query: 998 ENI-----VKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITG 1052
N+ + ++ +E+ + + SP+ + + T K+ S ++ +
Sbjct: 501 TNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQ 560
Query: 1053 TPRKAHSKSAKEHQETKP--VKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG 1110
K +P V+ + + ++ + S K +EK+K ++K+ L+ G
Sbjct: 561 EHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSK--HQKDFHLEF-G 617
Query: 1111 EKRKRKTEEKGVDKDFESSSMKISKL--EVTEIVKPSPKRK-MEPDTEKMDRTPEKDKIS 1167
EK K +++ FE+S + K+ E + K K K E + K + EK+K
Sbjct: 618 EKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYK 677
Query: 1168 LSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGS 1227
AK+++ + E ++ EN + E + + + + K K+ + + + +
Sbjct: 678 TKDSAKELQRSVEFDREFWK-ENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKST 736
Query: 1228 SSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKW 1287
V ++K EK+ + + EE N T S++
Sbjct: 737 KEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDK-----------DSEF 785
Query: 1288 DKDDFESEEEDV--KSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKD 1345
+ EE + + + K IK KP + EK+ E E+ + F K+
Sbjct: 786 TSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMER-KTFEKE 844
Query: 1346 VSHEIIQHEVKSSKN----SASSEKGKTKDRDYSV-LEK--ENPEKRKNSTQPEKESNLD 1398
I+HE KS K+ S +K K KD+ YS EK + EK KN+ +K + +
Sbjct: 845 KK---IKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE 901
Query: 1399 RLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKR-RDEK 1457
+ E+ + K KE ++H S K ++K++D EYS S++ ++++
Sbjct: 902 KSREKMDRKH----DKEKPEKERH--LAESKEKHLMEKKNKQSD--NSEYSKSEKGKNKE 953
Query: 1458 NELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKA-TYD 1516
+ K SR+K+S + +K +E G+ + S K D T D
Sbjct: 954 KDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPD 1013
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS 1576
K +++ K +D+ +D+ K ++ N LL + + +
Sbjct: 1014 GKEKDKKDKDIDRYKERDKHKDKIQI--------NSLLKLKSEAD--------------- 1050
Query: 1577 TVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIV 1636
KPKP+ SS S D TR ++ D ++ E +S+K+ E K K+KI
Sbjct: 1051 --KPKPK---SSPASKD-TRPKEKRLVNDDLMQTSFERMLSLKDLEIE-QWHKKHKEKIK 1103
Query: 1637 EKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK 1696
+K KE L +++ I + H+P+ S+ + + S SS + K+K
Sbjct: 1104 QKEKERLRNRNCLELKIKDKEK---------TKHTPTESKNKELTRSKSSEVTDAYTKEK 1154
Query: 1697 KKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK 1738
+ K+ ++ K+ G + + ++ + +++K
Sbjct: 1155 QPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENEK 1196
Score = 68.6 bits (166), Expect = 5e-11
Identities = 199/994 (20%), Positives = 358/994 (36%), Gaps = 158/994 (15%)
Query: 882 SKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLF 941
+K +SEN+ D N +K R+ ++ + +E S S+E K F
Sbjct: 7 TKPIQSENSDSDS--NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPF 64
Query: 942 VL-PSRDDATPVRDEPMDAES------------ITFKSVSEKDKRERDKPKAKGDKTKRK 988
+ PSR++ RD D++ ++++ SEK+ E+ K K + K
Sbjct: 65 TISPSRNEE---RDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGNKKST 121
Query: 989 ND----GSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1044
G +S+++ + + R+ SP S P + TP T SSSS
Sbjct: 122 PVSILFGYPLSERKQMALLMQMTA------RDNSPDSTP--NHPSQTTPAQKKTPSSSSR 173
Query: 1045 QKDEKITGTPR-KAHSKSAKEHQETKPVKE------EKVKKDYS-------------KDV 1084
QKD+ R + A + K VKE KD++ DV
Sbjct: 174 QKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDV 233
Query: 1085 KSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR---KTEEKGVDKDFESSSMKISKLEV--T 1139
+ + + + + PL + R K + F+++ ++V T
Sbjct: 234 AKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAET 293
Query: 1140 EIVKPSPKRK--MEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEP 1197
E ++ KR+ + D E + E ++ S+ + I E I ++ I +K P
Sbjct: 294 EELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTP 353
Query: 1198 -----------SEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVR 1246
+ E + + + K +RK E + L + P
Sbjct: 354 LPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLF---AKQEKAFYPKS 410
Query: 1247 KSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPIS 1306
+K R + + E + + + +P++ D ++++E V S +
Sbjct: 411 FKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPET--SNSDMQTKKEYVVSGEH-K 467
Query: 1307 SVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFT----------------------- 1343
GK +KN + N EKE + + +I T
Sbjct: 468 QKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSP 527
Query: 1344 KDVSHEIIQH--EVKSSKNSAS-SEKGKTKDRDYSVLEKENPEKRKNSTQPE----KESN 1396
KD + + H KS K+S SEK T + +P + S QP+ +
Sbjct: 528 KDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTE 587
Query: 1397 LDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSN-----KDFTPNRDKKTDYDTREYSSS 1451
+ L E + KS K D H SN +D +P + +D ++
Sbjct: 588 SEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFE-NSDCTLKKMDKE 646
Query: 1452 KRRDEKNELTRRKDSPSRNKDSASGQKNKPREE---RDLPKKGTGDSK-------KSNSS 1501
+ +K++L ++ ++K G+K K + + ++L + D + KS+ +
Sbjct: 647 GKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDET 706
Query: 1502 PSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPE 1561
T + K E+ DK+ +EKHV + RN KE I E
Sbjct: 707 EDLFLNMEHESLTLEKKSKLEKNIKDDKS---TKEKHVSKERNFKEERDK----IKKESE 759
Query: 1562 TQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVS-VKE 1620
+E+I ++ P + S + L E+ E D E +KE
Sbjct: 760 KSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES--IGLHLVEKEIDIEKQEKHIKE 817
Query: 1621 EESSGNISKDLKDKIVEK------------------AKESLDTAAVVQVGISRNQ--SHS 1660
+ +K+K +EK K+ LD + V +++ SH
Sbjct: 818 SKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHH 877
Query: 1661 SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKH-----KKHKKHKKHKK 1715
+ S + + + S E D K K+K EK++H +KH KK+K+
Sbjct: 878 TEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQ 937
Query: 1716 HAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
+ E KS+K K+K+K + +K KEK ++K+
Sbjct: 938 SDNS--EYSKSEKGKNKEKDRELDK-KEKSRDKE 968
Score = 64.7 bits (156), Expect = 8e-10
Identities = 119/563 (21%), Positives = 210/563 (37%), Gaps = 117/563 (20%)
Query: 790 KERYREWERKYREWYEKYYKGYAAGAQPRPSANREN-FSPERFLPLNIRNSPFTRGRRED 848
KER +E +K E ++ YK + + + S + F E F F ED
Sbjct: 658 KEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENF---------FKSDETED 708
Query: 849 YVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKG 908
H S + EK S + N KD+ +KEK K K+ R + K
Sbjct: 709 LFLNMEHESLTL-----EKKSKLE-KNIKDDKSTKEKHVS------KERNFKEERDKIK- 755
Query: 909 EESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVS 968
+ESE E ++ ++ RE +++ + + + +++ + + + I +
Sbjct: 756 KESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLH---LVEKEIDIEKQE 812
Query: 969 EKDKRERDKPKAKG---DKTKRKNDGSAVSKKENIVKPAKGPQEK------VDGERERSP 1019
+ K ++KP+ + +K K + K++ I K ++K VD +E+
Sbjct: 813 KHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDK 872
Query: 1020 RSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKD 1079
+K +E K+ NT + + EK + K ++H + KP KE + +
Sbjct: 873 LYSHHTEKCHKEGEKSKNTAAIKKTDDREK-------SREKMDRKHDKEKPEKERHLAES 925
Query: 1080 YSKDV--KSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK--------TEEKGVDKDFESS 1129
K + K K + E +K KNK D + +K+++ T K + ++ +SS
Sbjct: 926 KEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSS 985
Query: 1130 SMKISK------LEVTEIVKPSP--------KRKMEPDTEK-MDRTPEKDKISLSAPAKK 1174
+ +K L + E K P K K + D ++ +R KDKI +++
Sbjct: 986 IVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINS---L 1042
Query: 1175 IKLNRETGKKIGSTENISNTKEPSEK------LESTS--------------------SKV 1208
+KL E K + S P EK L TS K+
Sbjct: 1043 LKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKI 1102
Query: 1209 KQE-------------KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGG--------SPVRK 1247
KQ+ K+K K + K T TE + L S+ T V
Sbjct: 1103 KQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN 1162
Query: 1248 SEEKTDTKRTVIKTMEEYNNDNT 1270
+ DTK + + +DN+
Sbjct: 1163 RSQSVDTKNVMTLGKSSFVSDNS 1185
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 98.2 bits (243), Expect = 6e-20
Identities = 198/910 (21%), Positives = 342/910 (37%), Gaps = 122/910 (13%)
Query: 882 SKEKESENAPGDGKGNKHKKHRKRR-KGEESEGFLNPELLETSRKSREPTGVEENKTDSL 940
SK +E NA + NK KK RK+ KG E + +S E + E+ DSL
Sbjct: 437 SKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSL 496
Query: 941 FVLPSRDDATPVRDEPMDAESITFKSVSE--KDKRERDKPKAKGDKTK--RKNDGSAVSK 996
+ V +P S++ S S ++ P TK R ++ +S
Sbjct: 497 GSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISS 556
Query: 997 K--ENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTP 1054
+ + + ++ E + S ++ K + ++ K +S S+K +
Sbjct: 557 PAWSEVSSLSDSTRTRLTSESDYSSEGSS-VESLKPVRKRQEHRKRASLSEKKSPFLSSA 615
Query: 1055 RKAHSKSAKEHQETKPVK-------EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLD 1107
A K KE + K K +EK + S+++K + T + E +K+ ++K L+
Sbjct: 616 EGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLE 675
Query: 1108 NKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDK-I 1166
N + K + D+D K+SK+++ E K + D + + R + +K I
Sbjct: 676 ND-LSTENKLKVLKHDRDHFKKEEKLSKMKLEE------KEWLFKDEKSLKRIKDTNKDI 728
Query: 1167 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEG 1226
S S +K + N+ E + KE S K E ++ +E+ K K + + + E
Sbjct: 729 SRSFREEKDRSNK--------AEKERSLKEKSPKEEKL--RLYKEERKKKSKDRPSKLEK 778
Query: 1227 SSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK 1286
+ D S K + K + +EY N N
Sbjct: 779 KNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQF--------------- 823
Query: 1287 WDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEK-IQKFTKD 1345
+ +D + D + + S + + K + S + Y + +S+ K I + K+
Sbjct: 824 LENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKE 883
Query: 1346 VSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGN 1405
S E + K + KDRDY L+K N EKRK T+ K
Sbjct: 884 DSKERRRDSRAREKRDYREPFFRKKDRDY--LDK-NSEKRKEQTEKHKSVP--------- 931
Query: 1406 FKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD 1465
LS+ K+ R S + R + + RD + +K + E +
Sbjct: 932 -GYLSEKDKKRRESAEAGRDRKDALESCKERRDGR----------AKPEEAHREELKECG 980
Query: 1466 SPSRNKDSASGQKNKPRE--ERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEE 1523
S KD + G K E ER P + K+ P ++RK Y K +++
Sbjct: 981 CESGFKDKSDGDFGKGLEPWERHHPAR----EKEKKDGPDKERKEKTKPERYKEKSSDKD 1036
Query: 1524 T--KSVDKNPCKDRE--KHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVK 1579
KS+ + KD+E K E ++ KE +T + ++ +D+ K
Sbjct: 1037 KSEKSILEKCQKDKEFDKCFKEKKDTKEKH----------KDTHGKDKERKASLDQG--K 1084
Query: 1580 PKPQLSHSSRLSSDLTRETDE----------AAFEPDYNESDSESNVS--VKEEESSGNI 1627
K + + +S D + + D+ A D +E D +S + K E+S
Sbjct: 1085 EKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLP 1144
Query: 1628 SKD-LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1686
D L++K E+ +E+ S SS P R R +A +
Sbjct: 1145 RTDGLQEK--EEGREAY---------ASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADA 1193
Query: 1687 AESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK----NKDK 1742
+ K +K KEKK + +K+K K A + +K K K +K KK +K K
Sbjct: 1194 GRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAK 1253
Query: 1743 EKEKEKDDQK 1752
K KEK D++
Sbjct: 1254 SKHKEKSDKE 1263
Score = 87.8 bits (216), Expect = 8e-17
Identities = 228/1216 (18%), Positives = 440/1216 (36%), Gaps = 147/1216 (12%)
Query: 607 APANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSYSRSSY 666
+P L P + S + + +++ ++ A + + + + ++ S ++S S
Sbjct: 505 SPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVS- 563
Query: 667 TYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRS 726
S S STR+R S S S S P +R + R S +S +
Sbjct: 564 ----SLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAV 619
Query: 727 PPYRRYHS---RSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVD 783
P + + ++ + + + ++ Q + + Y + D +
Sbjct: 620 PKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLS 679
Query: 784 F----------RDPFEKE-RYREWERKYREWYEKYYKGYAAGAQPRPSANRE-NFSPERF 831
RD F+KE + + + + +EW K K +R +R
Sbjct: 680 TENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRS 739
Query: 832 LPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAP 891
S + +E+ + + + P KL ++ + K++ SKEKE
Sbjct: 740 NKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKN--DLKEDKISKEKEKIFKE 797
Query: 892 GDGKGNKHKKHRKRRKGEE---SEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDD 948
K K K +R+ +E FL E + S + + +DS F D
Sbjct: 798 DKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDS 857
Query: 949 ----ATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPA 1004
T RD D+ + ++D +ER + +K + ++ + K +
Sbjct: 858 WDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNS 917
Query: 1005 KGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKI-TGTPRKAHSKSAK 1063
+ +E+ + + KK +E + K + S K+ + P +AH + K
Sbjct: 918 EKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELK 977
Query: 1064 EHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRK-RKTEEKGV 1122
E K+ K D+ K ++ + + A++ +K+ P + EK K + +EK
Sbjct: 978 ECGCESGFKD-KSDGDFGKGLEPWE---RHHPAREKEKKDGPDKERKEKTKPERYKEKSS 1033
Query: 1123 DKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETG 1182
DKD S+ EK + E DK K K G
Sbjct: 1034 DKDKSEKSI----------------------LEKCQKDKEFDKCFKEKKDTKEKHKDTHG 1071
Query: 1183 KKIGSTENISNTKEPSEK----LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTS 1238
K ++ KE EK + S K++ KGK + + + D S
Sbjct: 1072 KDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCM 1131
Query: 1239 STGGSPVRKSE-EKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEE 1297
+G S+ +TD + + E Y +D + D Q P+ + DK E
Sbjct: 1132 GSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDK----QHPERQKDK-----EPR 1182
Query: 1298 DVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKD-VSHEIIQHEV- 1355
D + + + G+ K K+ EK+ + S + K KD S + Q +
Sbjct: 1183 DRRKDRGAADAGR--------DKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKN 1234
Query: 1356 ------KSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSL 1409
K+ K A+ +K K+K ++ S +KE+ ++RK+S + E +L + L
Sbjct: 1235 KQKLPEKAEKKHAAEDKAKSKHKEKS--DKEHSKERKSSRSADAEKSL--------LEKL 1284
Query: 1410 SQSSKEARTSDKHDSTRASSNKDFTPNRDK------------KTDYDTREYSSSKRRDEK 1457
+ + D +D S+ FT + + D + S+ ++
Sbjct: 1285 EEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKL 1344
Query: 1458 NELTRRKDSPSRNKDSASGQKNKPREERDLPKKGT----GDSKKSNSSPSRDRKPHD-HK 1512
E R + S S +K S ++ K +E+ + +KG G S+K + +D D +
Sbjct: 1345 KEKERHRHSSSSSKKSHDRERAK-KEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYG 1403
Query: 1513 ATYDTKRPNEET--KSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQIT 1570
+Y+ K E+ K+++ + ++K+ E +K+ K L + KE+
Sbjct: 1404 VSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIE--KELKPYGSSAINILKEKKK 1461
Query: 1571 GQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKD 1630
+ + + + + L DE E + ++++S +
Sbjct: 1462 REKHREKWRDEKERHRDRHADGLLRHHRDELL-----RHHRDEQKPATRDKDSPPRV--- 1513
Query: 1631 LKDKIVE--------KAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1682
LKDK + K KE A + G S+ + V+PS+ ++ R
Sbjct: 1514 LKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLL 1573
Query: 1683 SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDK 1742
++ +K+ + ++HK+HK+ K + +K +H +S K K
Sbjct: 1574 GDGDLMMTSFERMLSQKDLEIEERHKRHKERMK---------QMEKLRH---RSGDPKLK 1621
Query: 1743 EKEKEKDDQKVKSVTV 1758
EK K DD + K + +
Sbjct: 1622 EKAKPADDGRKKGLDI 1637
Score = 82.8 bits (203), Expect = 3e-15
Identities = 166/839 (19%), Positives = 303/839 (36%), Gaps = 126/839 (15%)
Query: 982 GDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSS 1041
G T ++ S+ E P+ P VDG S + KAK P
Sbjct: 285 GKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEP-------- 336
Query: 1042 SSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEK--VKKDYSKDVKSEKLTTKEEKAKKP 1099
+K T + + + Q+ P ++K +KKDY K+ KS + + K
Sbjct: 337 ------QKATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKS 390
Query: 1100 NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKIS-----KLEVTEIVKPSPKRKMEPDT 1154
KN + K + ++ D E +S+ + +L I+ S R+
Sbjct: 391 YTKNNTIAPKKASHRILSD----TSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAK 446
Query: 1155 EKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVK 1214
++ ++ K K ++++ + + K S+E+ S + E E + S +K
Sbjct: 447 QQKEKNKVKKKRKKETKGREVRFGKRS-DKFCSSESESESSESGE--DDRDSLGSSGCLK 503
Query: 1215 GKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAE 1274
G + + S + + +STSS G S +K + T + + ++
Sbjct: 504 GS---PLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWS 560
Query: 1275 DVIIMIQVPQSK-WDKDDFESEEEDVKSTQP---------------------------IS 1306
+V + +++ + D+ SE V+S +P +
Sbjct: 561 EVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVP 620
Query: 1307 SVGKPASVIKNVSTKPSNIVKYP------------------EKESEPSEKIQKFTKDVSH 1348
+ K V+K TK + K E + S+K D+S
Sbjct: 621 KLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLST 680
Query: 1349 E----IIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKES---NLDRLN 1401
E +++H+ K K K +++++ ++++ ++ K++ + S DR N
Sbjct: 681 ENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSN 740
Query: 1402 EQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELT 1461
+ +SL + S + + R +KD +KK D + S K + K +
Sbjct: 741 KAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKE 800
Query: 1462 RRKDSPSRNKDSASGQ---KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHD-HKATYDT 1517
+ K +DSA + KN+ E D+K S S RDR D +++D
Sbjct: 801 KLKKEKVYREDSAFDEYCNKNQFLENE--------DTKFSLSDDQRDRWFSDLSDSSFDF 852
Query: 1518 KRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKST 1577
K + + V + R+ K S KL+ +++ + + +
Sbjct: 853 KGED------------SWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDY 900
Query: 1578 VKP---KPQLSHSSRLSSDLTRETDEAAFEPDY-NESDSESNVSVKEEESSGNISKDLKD 1633
+P K + + S +T++ P Y +E D K+ S +D KD
Sbjct: 901 REPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKD-------KKRRESAEAGRDRKD 953
Query: 1634 KIVEKAKESLDTAAVVQVGISRNQSH---SSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1690
+ E KE D A + S S G + A E +
Sbjct: 954 AL-ESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKK 1012
Query: 1691 DSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
D K++KEK K +++K+ K + + LEK QK K K K+ KD KEK KD
Sbjct: 1013 DG-PDKERKEKTKPERYKEKSSDKDKSEKSI-LEKCQKDKEFDKCFKEKKD-TKEKHKD 1068
Score = 55.5 bits (132), Expect = 5e-07
Identities = 97/394 (24%), Positives = 155/394 (39%), Gaps = 71/394 (18%)
Query: 1414 KEARTSDKHDSTRASSNKD---FTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRN 1470
K TS + ST +S +D F P+ + E+ + KN ++ +P ++
Sbjct: 286 KGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKD 345
Query: 1471 K----DSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526
+ + + P +++ L KK KSNS S P E KS
Sbjct: 346 EYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISI---------------PKMEVKS 390
Query: 1527 VDKN----PCKDREKHVLEARNNKESS-----GNKL---LYILNPPETQVEKEQITGQID 1574
KN P K + + + + +++S G KL + + P E Q +
Sbjct: 391 YTKNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKE 450
Query: 1575 KSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDK 1634
K+ VK K + R + +D+ +ES+SES+ S +++ S S LK
Sbjct: 451 KNKVKKKRKKETKGR-EVRFGKRSDKFCS----SESESESSESGEDDRDSLGSSGCLKGS 505
Query: 1635 -IVEKAKE---SLDTAAVVQVGIS----RNQSH----------------SSPSVSPSRSH 1670
+V K SL ++ G S +N SH SSP+ S S
Sbjct: 506 PLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSL 565
Query: 1671 SPSGSQTR-----SHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEK 1725
S S ++TR +SS SS ES +K+++ K+ KK G +L+K
Sbjct: 566 SDS-TRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDK 624
Query: 1726 SQK--HKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1757
K KHK K KNK+K + + K+KS T
Sbjct: 625 EGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFT 658
Score = 34.7 bits (78), Expect = 0.84
Identities = 87/439 (19%), Positives = 165/439 (37%), Gaps = 40/439 (9%)
Query: 1345 DVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQP--EKESNLDRLNE 1402
D E+ + K + G+ KD D EK+ PE+++ +P K L +
Sbjct: 46 DGGKEVRERASKRKLPFTAGANGEQKDSD---TEKQGPERKRIKKEPVTRKAGLLFGMGL 102
Query: 1403 QGNFKS--LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTR--EYSSSKRRDEKN 1458
G LS+ + A A+S D TP ++ + S+SK +D+ N
Sbjct: 103 SGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVN 162
Query: 1459 ELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTK 1518
+ R ++ + + + R ++L +G + K + + + ++ YD
Sbjct: 163 KRNERGET----RLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEA-CNRGYYDVA 217
Query: 1519 RPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLL--YILNPPETQVEKEQITGQIDKS 1576
+ + D + + +A NN KLL Y NP ++ + E +
Sbjct: 218 KQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSP 277
Query: 1577 T----VKPKPQLSHSSRLSSDLTRETDEAAFEP----DYNESDSESNVSVKEEESSGNIS 1628
T + K + S S++ + E D +F P D N +DSE +K + +
Sbjct: 278 TMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQ 337
Query: 1629 K---DLKDKIVEKAKESLDTAAVVQ-----VGISRNQSHSSPSVSPSRSHSPSGSQTR-- 1678
K +KD+ + D V R ++ S+ +S + S ++
Sbjct: 338 KATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTI 397
Query: 1679 -----SHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKK 1733
SH + +++ +D+ EK + H K + + +K +K+K KK
Sbjct: 398 APKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQK-EKNKVKK 456
Query: 1734 KKSKKNKDKEKEKEKDDQK 1752
K+ K+ K +E K K
Sbjct: 457 KRKKETKGREVRFGKRSDK 475
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 97.8 bits (242), Expect = 8e-20
Identities = 131/637 (20%), Positives = 257/637 (40%), Gaps = 107/637 (16%)
Query: 1016 ERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEK 1075
E P+S+ +KK +++ K+ ++ SSSSS D + S+S+ + +++ EEK
Sbjct: 176 ELIPKSK--VKKEEKKRHKSSSSSSSSSSDSDSS-------SDSQSSSDSSDSESATEEK 226
Query: 1076 VKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISK 1135
KK K K+ + KE+K +K ++K+ +++ E + + + ++
Sbjct: 227 SKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIP----- 281
Query: 1136 LEVTEIVKPSPKRKMEPDTEKMDRTPEKD---KISLSAPAKKIKLNRETGKKIGS----- 1187
E +++ SP + E + + +R E++ S A ++ L +G+KI
Sbjct: 282 -ENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRR 340
Query: 1188 --TENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1245
T + S +++ + E T +QE + + R +G + SPV
Sbjct: 341 YRTPSRSRSRDRFRRSE-TPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 1246 RKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPI 1305
R E K R V +S K++ E + +D KS
Sbjct: 400 RVKERKITDHR------------------------NVSESPNRKNEKEKKVKDHKS---- 431
Query: 1306 SSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSE 1365
++K +I + EK+ + K++K KS S S E
Sbjct: 432 -------------NSKERDIRRNSEKDDKYKNKVKK------------RAKSKSRSKSKE 466
Query: 1366 KGKTKDRDYSVLEKENPEKR----------KNSTQPEKESNLDRLNEQGNFKSLSQSSKE 1415
K K+K+RD N EKR +N + EK+S+ + +Q +S +S +
Sbjct: 467 KSKSKERDSK--HNRNEEKRMRSRSKGRDHENVKEKEKQSD-SKGKDQERSRSKEKSKQL 523
Query: 1416 ARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKR---RDEKNELTRRKDSPSRNKD 1472
S++HD +++ +R ++ D ++S + R R + +RR S + ++D
Sbjct: 524 ESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRD 583
Query: 1473 SASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPC 1532
+ ++ E++ ++G S++ + P R R + D+ R +E +S +N
Sbjct: 584 RSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS-RSSEREESQSRNKD 642
Query: 1533 KDREKHVLEARNNKESSGNKLLYIL----NPPETQVEKEQITGQIDKSTVKPKPQLSHSS 1588
K R + + + S K +Y N EK+ Q S +K Q S +
Sbjct: 643 KYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIK---QSSQDN 699
Query: 1589 RLSSDLTRETDE----AAFEPDYNESDSESNVSVKEE 1621
L S + + ++ ++ E + +S + N V E+
Sbjct: 700 ELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEK 736
Score = 83.6 bits (205), Expect = 2e-15
Identities = 132/621 (21%), Positives = 237/621 (38%), Gaps = 91/621 (14%)
Query: 855 HRSRNIGSNYPEKLSARDGHNQKDNTKSKEK-ESENAPGDGKGNKHKKHRKRRKGEESEG 913
H+S + S+ S+ D + D+ S + +SE+A + + KKHRK + + E
Sbjct: 191 HKSSSSSSS-----SSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKE- 244
Query: 914 FLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPM-DAESITFKSVSEKDK 972
+ RK + + E++ ++L P + P P+ + + KS + D+
Sbjct: 245 -------KKKRKKSKKSASSESEAENLEAQP-QSTVRPEEIPPIPENRFLMRKSPPKADE 296
Query: 973 RERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERE-RSP-RSEPPIKKAKE 1030
+ER + + ++ + S + ++ G + K G R R+P RS + +
Sbjct: 297 KERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRS 356
Query: 1031 ETP-----KTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVK 1085
ETP + + S + I G K+ KE+Q + PV+ VK
Sbjct: 357 ETPPHWRQEMQRAQRMRVSSGERWIKGD--KSELNEIKENQRS-PVR-----------VK 402
Query: 1086 SEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPS 1145
K+T ++ PN KN+ + K + K ++E+ + ++ E +K++ K
Sbjct: 403 ERKITDHRNVSESPNRKNEK-EKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461
Query: 1146 PKRKMEPDTEKMD----RTPEKDKISLS--APAKKIKLNRETGKKIGSTENISNTKEPSE 1199
K K + +++ D R EK S S + +K + G + S +KE S+
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK 521
Query: 1200 KLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVI 1259
+LES S++ K K K RR S S D T + S R+ D R V
Sbjct: 522 QLESKSNEHDHSKSKEKDRR-----AQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVR 576
Query: 1260 KTM----------------EEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ 1303
+EY + + + + P + D D +S++
Sbjct: 577 SRTHDRDRSRSKEYHRYREQEYRRRGRSRSRE----RRTPPGRSRSKDRRRRRRDSRSSE 632
Query: 1304 PISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS 1363
S + +N +K S+ KE+ SEK + ++K H NS++
Sbjct: 633 REESQSRNKDKYRNQESKSSH-----RKENSESEK-RMYSKSRDH-----------NSSN 675
Query: 1364 SEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHD 1423
+ + K DRD S K + N + N + + + + +Q SK H+
Sbjct: 676 NSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHE 735
Query: 1424 STRASSNKDFTPNRDKKTDYD 1444
NK F TD D
Sbjct: 736 -----KNKKFDHESSPGTDED 751
Score = 80.1 bits (196), Expect = 2e-14
Identities = 122/581 (20%), Positives = 215/581 (37%), Gaps = 76/581 (13%)
Query: 1206 SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEY 1265
SKVK+E+ K R K + + SSS+ D +S+ S S SE T+ K K
Sbjct: 181 SKVKKEEKK---RHKSSSSSSSSSSDSD-SSSDSQSSSDSSDSESATEEKSKKRKKKHRK 236
Query: 1266 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNI 1325
N+ + + K K E + QP S+V +P I
Sbjct: 237 NSRKHKKEKK-------KRKKSKKSASSESEAENLEAQPQSTV------------RPEEI 277
Query: 1326 VKYPEKE----SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKEN 1381
PE P + +K K+ E + + AS ++ R ++
Sbjct: 278 PPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRG 337
Query: 1382 PEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTS--------DKHDSTRASSNKDF 1433
P + + ++ R +++ Q ++ R S DK + N+
Sbjct: 338 PRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRS 397
Query: 1434 TPNRDKKTDYDTREYSSS-KRRDEKNELTRRKDSPSRNKD----SASGQKNKPREERDLP 1488
++ D R S S R++EK + + S S+ +D S K K + ++
Sbjct: 398 PVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAK 457
Query: 1489 KKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES 1548
K SK+ + S RD K + + + KR +K D K++EK ++E
Sbjct: 458 SKSRSKSKEKSKSKERDSKHNRN----EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQER 513
Query: 1549 SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN 1608
S +K E + E + + D S K K + + S D+T+ + YN
Sbjct: 514 SRSK--------EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKG------KHSYN 559
Query: 1609 ESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSR 1668
E + S + + D +D+ K + G SR++ +P P R
Sbjct: 560 SRTRERSRSRDRSRRVRSRTHD-RDRSRSKEYHRYREQEYRRRGRSRSRERRTP---PGR 615
Query: 1669 SHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQK 1728
S S + R S S+ ESQ K K + ++ K K++ + +K ++ S
Sbjct: 616 SRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSN 675
Query: 1729 HKHKKKKSK--------KNKDKEKE------KEKDDQKVKS 1755
+ +KK + K ++ E K K+D+K++S
Sbjct: 676 NSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS 716
Score = 75.1 bits (183), Expect = 6e-13
Identities = 109/554 (19%), Positives = 218/554 (39%), Gaps = 72/554 (12%)
Query: 625 SNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRS 684
S++ T+ R++ +R+ R ++ K S S SS + +++ +S
Sbjct: 217 SDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEE 276
Query: 685 FSRSHSRSY--SRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAF 742
+ +SPP + K R R R R + S+ Y+R +RS +
Sbjct: 277 IPPIPENRFLMRKSPP---KADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKI 333
Query: 743 RGQSPNKRNVPQGETEREYFNRYREVPPPY--------DMKAYYGRSVDFRDPFEKERYR 794
+G+ P + P R+ F R E PP + M+ G D E +
Sbjct: 334 KGRGPRRYRTPSRSRSRDRFRR-SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIK 392
Query: 795 EWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQS 854
E +R E+ + ++ S NR+N E+ + + NS +E + S
Sbjct: 393 ENQRSPVRVKERKITDHRNVSE---SPNRKN-EKEKKVKDHKSNS------KERDIRRNS 442
Query: 855 HRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGF 914
+ + ++ ++ K+ +KSKE++S++ N+ K+ R R KG + E
Sbjct: 443 EKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH-----NRNEEKRMRSRSKGRDHENV 497
Query: 915 LNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDK-- 972
E S+ + + K+ L + D + +++ A+S + + K K
Sbjct: 498 KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHS 557
Query: 973 -----RERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKK 1027
RER + + + + + + S+ + + + + R R R+ P +
Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSR 617
Query: 1028 AKEETPKTDNTKSSSSSQ---------KDEKITGTPRKAHSKSAK-------EHQETKPV 1071
+K+ + +++SS + ++++ + RK +S+S K +H +
Sbjct: 618 SKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNS 677
Query: 1072 KEEKVKKDYS-----------KDVKSEKLTTKEEK-----AKKPNEKNKPLDNK--GEKR 1113
+E+K +D S ++KS L KE++ +K N+K+K +N EK
Sbjct: 678 REKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKN 737
Query: 1114 KRKTEEK--GVDKD 1125
K+ E G D+D
Sbjct: 738 KKFDHESSPGTDED 751
Score = 71.6 bits (174), Expect = 6e-12
Identities = 84/445 (18%), Positives = 170/445 (38%), Gaps = 62/445 (13%)
Query: 1342 FTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLN 1401
F + +S + + E+++ K A+S K + R S E K K + +S+ +
Sbjct: 141 FGQVISGQEVVREIENQKTDAAS-KPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSS 199
Query: 1402 EQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELT 1461
+ S S S + +SD +T S K R KK ++R++ K++ +K++ +
Sbjct: 200 SSSDSDSSSDSQSSSDSSDSESATEEKSKK-----RKKKHRKNSRKHKKEKKKRKKSKKS 254
Query: 1462 RRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN 1521
+S + N ++ +P E +P+ K + ++RK + + + PN
Sbjct: 255 ASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPN 314
Query: 1522 EETKSVDKNPCKDREKHVLEARN-------NKESSGNKLLYILNPPETQVEKEQ------ 1568
+ S + R ++ R ++ S ++ PP + E ++
Sbjct: 315 SQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRV 374
Query: 1569 ------ITG---------QIDKSTVKPKPQ-LSHSSRLSSDLTRETDEAAFEPDYNESDS 1612
I G + +S V+ K + ++ +S R+ ++ D+ +
Sbjct: 375 SSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSK 434
Query: 1613 ESNV---SVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRS 1669
E ++ S K+++ + K K K K+KE S+++ S
Sbjct: 435 ERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEK-----------SKSKERDSKHNRNEEK 483
Query: 1670 HSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKH 1729
S S+ R H + + DSK K +++ + K K + K S +H
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESK-------------SNEH 530
Query: 1730 KHKKKKSKKNKDKEKEKEKDDQKVK 1754
H K K K + + + +E D K K
Sbjct: 531 DHSKSKEKDRRAQSRSRECDITKGK 555
Score = 71.2 bits (173), Expect = 8e-12
Identities = 134/662 (20%), Positives = 239/662 (36%), Gaps = 102/662 (15%)
Query: 647 RLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGK 706
++K+E K + SS S SS + S S S S S S S S + +S R
Sbjct: 182 KVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRK---------- 231
Query: 707 SRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYR 766
+ +R SR H + + + +S+ + ++ N PQ E
Sbjct: 232 -KKHRKNSRKHKKEKKKRK---------KSKKSASSESEAENLEAQPQSTVRPE------ 275
Query: 767 EVPPPYDMKAYYGRSVDFRDPFE-KERYREWERKYREWYEKYYKGYAAGAQPRPSANREN 825
E+PP + + +S D E K R RE ER+ N N
Sbjct: 276 EIPPIPENRFLMRKSPPKADEKERKNRERERERE---------------------CNPPN 314
Query: 826 FSPERFLPLNIRNSPFTR-GRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKE 884
P + R TR GR+ G + +R+ P + +RD + +
Sbjct: 315 SQPASYQ----RRLLVTRSGRKIKGRGPRRYRT-------PSRSRSRDRFRRSETPPHWR 363
Query: 885 KESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENK-TDSLFVL 943
+E + A + + + KG++SE L E R P V+E K TD V
Sbjct: 364 QEMQRA----QRMRVSSGERWIKGDKSE------LNEIKENQRSPVRVKERKITDHRNVS 413
Query: 944 PS----RDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKEN 999
S + V+D +++ + SEKD + ++K K + R KE
Sbjct: 414 ESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER 473
Query: 1000 IVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHS 1059
K + ++++ R RS + K KE K S S KD++ + + K+
Sbjct: 474 DSKHNRNEEKRM---RSRSKGRDHENVKEKE--------KQSDSKGKDQERSRSKEKSKQ 522
Query: 1060 KSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEE 1119
+K ++ +EK ++ S+ + + K + E+++ D R R+
Sbjct: 523 LESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD-----RSRRVRS 577
Query: 1120 KGVDKDFESSSMKISKLEVTEIVKPSPKRKME---PDTEKMDRTPEKDKISLSAPAKKIK 1176
+ D+D S S + + E + R E P + + + + ++
Sbjct: 578 RTHDRD-RSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREES 636
Query: 1177 LNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTS 1236
+R K S+ KE SE + SK + R K + S + + +S
Sbjct: 637 QSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSS 696
Query: 1237 TSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEE 1296
+ S + K++E + +V E+ N + D + K+D + +
Sbjct: 697 QDNELKSSMLKNKEDEKIRSSV----EKENQKSKGQEND---HVHEKNKKFDHESSPGTD 749
Query: 1297 ED 1298
ED
Sbjct: 750 ED 751
Score = 37.0 bits (84), Expect = 0.17
Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 36/138 (26%)
Query: 1620 EEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRS 1679
E + + SK + + E + + V + R++S SS S S S S S S SQ
Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQ--- 211
Query: 1680 HSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN 1739
SS+ S++S+ + ++K KK KKKH K +
Sbjct: 212 --SSSDSSDSESATEEKSKKRKKKH-------------------------------RKNS 238
Query: 1740 KDKEKEKEKDDQKVKSVT 1757
+ +KEK+K + KS +
Sbjct: 239 RKHKKEKKKRKKSKKSAS 256
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 97.4 bits (241), Expect = 1e-19
Identities = 208/939 (22%), Positives = 336/939 (35%), Gaps = 193/939 (20%)
Query: 657 SGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRS 716
S ++ S+S S+SRS S RSRS S S SRS SRS SRS R R S RSRS S
Sbjct: 2 SKTNKSKSGSRSSRSRSAS-RSRSRSFSKSRSRSRSLSRS-----RKRRLSSRSRSRSYS 55
Query: 717 HGYHRSRSRSPPYR----RYHSRS-RSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPP 771
++R R+ Y+ R H+R R P FRG+ N+ P G+ R + YR
Sbjct: 56 PAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGR--NRGFYPWGQYNRGGYGNYRS---- 109
Query: 772 YDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERF 831
W+ YR+ Y PR +R SP+R
Sbjct: 110 -----------------------NWQ-NYRQAY-----------SPRRGRSRSR-SPKRR 133
Query: 832 LPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESEN-- 889
P SP +R + S RSR S+ +R +++ + K K+ S++
Sbjct: 134 SP-----SPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSR 188
Query: 890 ---APGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSR 946
A GD +G++ K+ + G S+ + +S +P T S +
Sbjct: 189 PSQAAGDNQGDEAKE--QTFSGGTSQD-------TKASESSKPWPDATYGTGSASRASAV 239
Query: 947 DDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKG 1006
+ +P P + V + R PK + GS +
Sbjct: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299
Query: 1007 PQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGT--------PRKAH 1058
Q G SP + P+ K+ P T +T SS ++ G +K
Sbjct: 300 GQFD-HGSGSLSPSKKSPVGKS---PPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTE 355
Query: 1059 SKSAKEHQETKPVKEEKVKKDYSKD-------VKSEKLTTKEEKAK----KPNEKNKPLD 1107
+ KE ++T KE+ +K D +KS+ K + K + K L
Sbjct: 356 NGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLR 415
Query: 1108 NKGEKRK---RKTEEKGVDKDFESSSMKISKLE-----VTEIVKPSPKRKME-------- 1151
+ EK+ K E DKD ++ K S+ + +++++ + ++ E
Sbjct: 416 DDFEKKMADFHKEEMDDQDKD-KAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGL 474
Query: 1152 ----PDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSK 1207
P EK +T E ++ S +KK + GK+ +E P + T+ K
Sbjct: 475 VYAPPGKEKQRKTEELEEESFPERSKK----EDRGKR---SEGGHRGFVPEKNFRVTAYK 527
Query: 1208 VKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNN 1267
QEK RK + + + G P KS + V M+ ++
Sbjct: 528 AVQEKSSSPPPRKTSESR---------DKLGAKGDFPTGKSSFSITREAQVNVRMDSFDE 578
Query: 1268 DNTAP----AEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1323
D P A++ + + S + +F S + ++S Q
Sbjct: 579 DLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQ-------------------- 618
Query: 1324 NIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPE 1383
+ PSE + + H + +H SS G T ++ K E
Sbjct: 619 -------SQRSPSELFAQHIVTIVHHVKEHHFGSS--------GMTLHERFTKYLKRGTE 663
Query: 1384 KR--KNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1441
+ KN PE +D S S K D+ S R K + K
Sbjct: 664 QEAAKNKKSPEIHRRID--------ISPSTFRKHGLAHDEMKSPREPGYK--AEGKYKDD 713
Query: 1442 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK---- 1497
D R +++ ++ +L R K S + +S + + E+ + KG+ KK
Sbjct: 714 PVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRA 773
Query: 1498 ---SNSSPSRDRKPHDHKA---TYDTKRPNEETKSVDKN 1530
S SS S + H +KA T +T+ E T DK+
Sbjct: 774 RDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKS 812
Score = 77.4 bits (189), Expect = 1e-13
Identities = 151/764 (19%), Positives = 280/764 (36%), Gaps = 116/764 (15%)
Query: 1015 RERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQ--ETKPVK 1072
R RSP+ P +++ + +D + S S R + S+S+ H E+ K
Sbjct: 126 RSRSPKRRSPSPRSRSHSRNSDKSSSDRSR----------RSSSSRSSSNHSRVESSKRK 175
Query: 1073 EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMK 1132
K KK SKD + + DN+G++ K +T G +D ++S
Sbjct: 176 SAKEKKSSSKDSRPSQAAG---------------DNQGDEAKEQTFSGGTSQDTKASESS 220
Query: 1133 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK-------- 1184
+ T + + + +R+P +L +P + + + R + +
Sbjct: 221 KPWPDATYGTGSASRASAVSELSPRERSP-----ALKSPLQSVVVRRRSPRPSPVPKPSP 275
Query: 1185 -IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGS 1243
+ ST + +T +S + + + + G + G S ST ST GS
Sbjct: 276 PLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPP-----STGSTYGS 330
Query: 1244 PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ 1303
++ + + +EE +N E Q+ DK E +K
Sbjct: 331 SQKEESAASGGAAYTKRYLEEQKTENGKDKEQ-------KQTNTDK-------EKIKEKG 376
Query: 1304 PISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS 1363
S G +K+ S P + P + S+ S K K D ++ + +
Sbjct: 377 SFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQ-SPKRYKLRDDFEKKMADFHKEEMDDQ-- 433
Query: 1364 SEKGKTKDRDYSVLEKENPEKRK----NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTS 1419
+K K K R S + E K N Q E++S G ++ L +
Sbjct: 434 -DKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS--------GKWEGLVYAPPG---K 481
Query: 1420 DKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRR-DEKN-ELTRRKDSPSRNKDSASGQ 1477
+K T + F P R KK D R + EKN +T K + + S+S
Sbjct: 482 EKQRKTEELEEESF-PERSKKEDRGKRSEGGHRGFVPEKNFRVTAYK---AVQEKSSSPP 537
Query: 1478 KNKPREERD-LPKKGTGDSKKSNSSPSRDRKPHDHKATYDTK--RPNEETKSVDKNPCKD 1534
K E RD L KG + KS+ S +R+ + + ++D RP+ + ++ C+D
Sbjct: 538 PRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSG-LLAQERKLCRD 596
Query: 1535 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS------ 1588
L N KE + + ++Q ++ Q + V + S
Sbjct: 597 -----LVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLH 651
Query: 1589 -RLSSDLTRETDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESL 1643
R + L R T++ A + P+ + S + ++ + + K ++ + +
Sbjct: 652 ERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYK 711
Query: 1644 DTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1703
D +++ I R + H + +S S S +S S+++ +K +K
Sbjct: 712 DDPVDLRLDIERRKKHKERDLKRGKSRE-----------SVDSRDSSHSRERSAEKTEKT 760
Query: 1704 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKE 1747
HK KK KKH++ S + H K + ++ E+ +E
Sbjct: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREE 804
Score = 47.4 bits (111), Expect = 1e-04
Identities = 102/483 (21%), Positives = 170/483 (35%), Gaps = 49/483 (10%)
Query: 642 YREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPR 701
YR + ++ SP G S SRS K RS S RSRS+SR+ +S S
Sbjct: 107 YRSNWQNYRQAYSPRRGRSRSRS----PKRRSPSPRSRSHSRNSDKSSS----------D 152
Query: 702 RGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPN---KRNVPQGETE 758
R R +S + RS S S+ +S ++ S+ P G + K G T
Sbjct: 153 RSR-RSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTS 211
Query: 759 REYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPR 818
++ + E P+ Y S + RE + + PR
Sbjct: 212 QD--TKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSV---VVRRRSPR 266
Query: 819 PSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQ-SHRSRNIGSNYPEKLSARDGHNQK 877
PS + P P G + GQ H S ++ + +
Sbjct: 267 PSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGS 326
Query: 878 DNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESE-GFLNPELLETSRK-SREPTGVEEN 935
S+++ES + G ++ + +K G++ E N + + K S TG+ +
Sbjct: 327 TYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDG 386
Query: 936 KTDSLFVLPSRDDATPVRDEP-------MDAESITFKSVSEKDKRERDKPKAKGDKTKRK 988
K S P D P R D +++ ++DK KAKG K
Sbjct: 387 KMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEF 446
Query: 989 NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDE 1048
+D K ++ K +E+ G+ E + P KE+ KT+ + S ++ +
Sbjct: 447 DDEPKFMSK--VIGANKNQEEEKSGKWEGLVYAPP----GKEKQRKTEELEEESFPERSK 500
Query: 1049 KITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDN 1108
K +S H+ P K +V K+ + + +K +E L
Sbjct: 501 K-----EDRGKRSEGGHRGFVPEKNFRVTA-----YKAVQEKSSSPPPRKTSESRDKLGA 550
Query: 1109 KGE 1111
KG+
Sbjct: 551 KGD 553
Score = 34.7 bits (78), Expect = 0.84
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 18/101 (17%)
Query: 1661 SPSVSPSRSHSPS----GSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKH 1716
SP SRS SP ++RSHS ++ + S S++ + H +
Sbjct: 119 SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR---------- 168
Query: 1717 AGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1757
VE K + K KK SK ++ + + + K T
Sbjct: 169 ----VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQT 205
Score = 33.9 bits (76), Expect = 1.4
Identities = 51/247 (20%), Positives = 89/247 (36%), Gaps = 42/247 (17%)
Query: 649 KEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSR 708
+E S S S RS+ K+ GS + + + R+ RS S S S + + +
Sbjct: 738 RESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTE 797
Query: 709 NYRSRSRSH-GYHRSRSRSP----PYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFN 763
R S G+ +SR + P R R+R FR + R +G N
Sbjct: 798 ETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARG---RGWGRGNYSGNNNN 854
Query: 764 RYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANR 823
DF+ ++ R EW+ +Y +KYY +R
Sbjct: 855 NSNN---------------DFQ---KRNREEEWDPEYTPKSKKYYL----------HDDR 886
Query: 824 ENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYP-EKLSARDGHNQKDNTKS 882
E ++++ F RGR G R + + +K S +G + D + +
Sbjct: 887 EGEGSDKWVSRGRGRGAFPRGR-----GRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGT 941
Query: 883 KEKESEN 889
+ +E ++
Sbjct: 942 ENREEKD 948
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 97.1 bits (240), Expect = 1e-19
Identities = 120/547 (21%), Positives = 210/547 (38%), Gaps = 70/547 (12%)
Query: 1246 RKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMI----------QVPQSKWDKDDFESE 1295
RKS + T K ++ ND + P + I + Q P KW + F
Sbjct: 25 RKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAHKWIRHSFRK- 83
Query: 1296 EEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESE------PSEKIQK------FT 1343
+ PI + + + +++ T +++ K K+S+ P +K K T
Sbjct: 84 ---ILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYAT 140
Query: 1344 KDVSHEIIQ-----------------HEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK 1386
S +I++ HE + SK S SS + + ++ + K +K K
Sbjct: 141 NPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDK 200
Query: 1387 NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFT----PNRDKKTD 1442
++ K++N + L+ + N K + SK + + S N DF + D+ +
Sbjct: 201 KDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESIN 260
Query: 1443 YDT--REYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNS 1500
+D R YS + ++ + T+ KD+ K E + K DSKK
Sbjct: 261 FDAWLRNYSQNNSKNYSLKYTKYT-----KKDTKKNAKKSSDAESEDSKDAKKDSKKVKK 315
Query: 1501 SPSRDRKPHD-HKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNP 1559
+ +D K D K T T + ++K K+ KD++K +++K+ K P
Sbjct: 316 NVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKL---KKDDKKKDTKKY-----P 367
Query: 1560 PETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVK 1619
T E K L +S+ + D ++ + F D +ES+ ES S K
Sbjct: 368 ESTDTESGDA-----KDARNDSRNLKKASK-NDDKKKDAKKITFSTD-SESELESKESQK 420
Query: 1620 EEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRS 1679
+E+ SK K V+ +ES D + + + + S+ ++
Sbjct: 421 DEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKN 480
Query: 1680 HSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN 1739
S+ ++ + K KK KEKK KK K K T+ E ++S K K K
Sbjct: 481 AESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKG 540
Query: 1740 KDKEKEK 1746
D E E+
Sbjct: 541 SDTESEE 547
Score = 70.9 bits (172), Expect = 1e-11
Identities = 89/396 (22%), Positives = 150/396 (37%), Gaps = 77/396 (19%)
Query: 1425 TRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREE 1484
T A F KT EY SK DEK +KDS + A+ ++K E
Sbjct: 92 TAAREQTPFRHLYTSKTHLKKAEYKKSK--DEKGGTPLKKDSKKKGGSYATNPESKQIVE 149
Query: 1485 RDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARN 1544
++ D SS ++ K++ +T ++ +K+V KN C ++K +++N
Sbjct: 150 EKTKRQNEADKTPLKSSHENEQSKKS-KSSSETNPESQNSKTVSKN-CSQKDKK--DSKN 205
Query: 1545 NKESSGNKLLYILNPPETQVEKEQ---------------------ITGQID--------- 1574
+K+++ + L+ N P+ +++ + + GQ D
Sbjct: 206 SKKTN-TEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAW 264
Query: 1575 --------------KSTVKPKPQLSHSSRLSSDLTRETDEAA------------------ 1602
K T K +++ SSD E + A
Sbjct: 265 LRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKK 324
Query: 1603 -FEPDYNESDSESNVSVKEEESSGN----ISKDLKDKIVEKAKESLDTAAVVQVGISRNQ 1657
+ D +D+ES S E + + + KD K K +K ES DT + +RN
Sbjct: 325 DVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESG-DAKDARND 383
Query: 1658 SHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHA 1717
S + S + + + S S ES++S+K +KK +KK K K
Sbjct: 384 SRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKK-DKKDSKTDNKKSVKNDEE 442
Query: 1718 GTEVELE-KSQKHKHKKKKSKKNKDKEKEKEKDDQK 1752
T+ + E K K KK + K KD +K+ +K D K
Sbjct: 443 STDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAK 478
Score = 70.9 bits (172), Expect = 1e-11
Identities = 88/359 (24%), Positives = 145/359 (40%), Gaps = 41/359 (11%)
Query: 857 SRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNK--HKKHRKRRKGEESEGF 914
S+N NY K + + +KD K+ +K S+ D K K KK +K K ++ +
Sbjct: 269 SQNNSKNYSLKYTK---YTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKK-- 323
Query: 915 LNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRE 974
+ +K E T E + +D +D D + T K D
Sbjct: 324 ------KDVKKDTESTDAESGDSKDERKDTKKDKKKLKKD---DKKKDTKKYPESTDTES 374
Query: 975 RDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPK 1034
D A+ D K SK ++ K AK D E E + +K ++ K
Sbjct: 375 GDAKDARNDSRNLKK----ASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSK 430
Query: 1035 TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQE-TKPVKEEKVKKDYSKDVKSEKLTTK- 1092
TDN KS + ++ P+ K K+ ++ K K++ KKD K+ +S ++ +
Sbjct: 431 TDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDL 490
Query: 1093 EEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSS---------MKISKLEVTE-IV 1142
E K K + K K K K+ + + + D +F+ SS +K S E E +
Sbjct: 491 ELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLY 550
Query: 1143 KPSPKRKMEPD-----TEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKE 1196
KP K+K++ KM+ K +S +KK N E G+K ST + ++E
Sbjct: 551 KPGAKKKIDESDGTSANSKMEGLESKRGFRMS--SKKTTFN-EKGEK-ASTGRVPPSRE 605
Score = 70.1 bits (170), Expect = 2e-11
Identities = 114/539 (21%), Positives = 204/539 (37%), Gaps = 55/539 (10%)
Query: 1055 RKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNK-PLDNKGEKR 1113
+KA K +K+ + P+K++ KK S E EEK K+ NE +K PL + E
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170
Query: 1114 KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAK 1173
+ K + + + ES + K ++ K K + +TE + + + P K
Sbjct: 171 QSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLH--------TKNNPKK 222
Query: 1174 KIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVD 1233
+K ++ + I SE S V + G+ + + + L +
Sbjct: 223 DLKRSKTSNDPI------------SEICSENSLNVDFLMLVGQSDDESINFD---AWLRN 267
Query: 1234 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED---VIIMIQVPQSKWD-- 1288
Y+ +S S K DTK+ K+ + + D+ +D V ++ K D
Sbjct: 268 YSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVK 327
Query: 1289 KDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSH 1348
KD ++ E S K +K K + KYPE S + D
Sbjct: 328 KDTESTDAESGDSKDERKDTKKDKKKLKK-DDKKKDTKKYPESTDTESGDAKDARNDS-- 384
Query: 1349 EIIQHEVKSSKNSASSEKGK--TKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF 1406
++ K+SKN + K T D S E E+ E +K+ + +K+S D N
Sbjct: 385 ---RNLKKASKNDDKKKDAKKITFSTD-SESELESKESQKDEKKDKKDSKTDNKKSVKN- 439
Query: 1407 KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS 1466
+ S +A + K DS + ++ KK D K+ +KN + +S
Sbjct: 440 ---DEESTDADSEPKGDSKKGKKDEKKGKKDSKKDD--------KKKDAKKNAESTEMES 488
Query: 1467 PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526
K K K ++D+ K D++ +++ K +T E +S
Sbjct: 489 DLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEES 548
Query: 1527 VDKNPCKDR--EKHVLEARNNKESSGNKLLYILNPPET---QVEKEQITGQIDKSTVKP 1580
+ K K + E A + E +K + ++ +T + ++ TG++ S KP
Sbjct: 549 LYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKP 607
Score = 65.1 bits (157), Expect = 6e-10
Identities = 90/459 (19%), Positives = 182/459 (39%), Gaps = 49/459 (10%)
Query: 874 HNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVE 933
H T K+ E + + + G KK K++ G + NPE S++ E
Sbjct: 102 HLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYAT---NPE----SKQIVEEKTKR 154
Query: 934 ENKTDSLFVLPSRDD--------ATPVRDEPMDAESITFKSVSEKDKRE----------- 974
+N+ D + S ++ ++ E ++++++ K+ S+KDK++
Sbjct: 155 QNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVS-KNCSQKDKKDSKNSKKTNTEF 213
Query: 975 ---RDKPKAKGDKTKRKNDGSAVSKKEN------IVKPAKGPQEKVDGE---RERSPRSE 1022
++ PK ++K ND + EN ++ + E ++ + R S +
Sbjct: 214 LHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNS 273
Query: 1023 PPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSK 1082
+ K D K++ S E K SK K K VK++ KKD K
Sbjct: 274 KNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVK-----KNVKKDDKKKDVKK 328
Query: 1083 DVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIV 1142
D +S + + K ++ + K K + +K+ T++ D ES K ++ + +
Sbjct: 329 DTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLK 388
Query: 1143 KPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSE--- 1199
K S + D +K+ + + + S ++K + + K + +++ N +E ++
Sbjct: 389 KASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADS 448
Query: 1200 KLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSS--TGGSPVRKSEEKTDTKRT 1257
+ + S K K+++ KGK K + + + T S + S+EK +K+
Sbjct: 449 EPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKD 508
Query: 1258 VIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEE 1296
+ K + A ++ +K D ESEE
Sbjct: 509 IKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEE 547
Score = 54.7 bits (130), Expect = 8e-07
Identities = 69/280 (24%), Positives = 123/280 (43%), Gaps = 46/280 (16%)
Query: 1503 SRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET 1562
+R++ P H T T E K KD + +++K+ G+ Y NP
Sbjct: 94 AREQTPFRHLYTSKTHLKKAEYKK-----SKDEKGGTPLKKDSKKKGGS---YATNPESK 145
Query: 1563 QV--EKEQITGQIDKSTVKP--KPQLSHSSRLSSDLTRETDEA------AFEPDYNESDS 1612
Q+ EK + + DK+ +K + + S S+ SS+ E+ + + D +S +
Sbjct: 146 QIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKN 205
Query: 1613 ESNVSVKEEESSGNISKDLK------DKIVEKAKE-SLDTAAVVQVGISRNQSHSSPSVS 1665
+ + + N KDLK D I E E SL+ ++ VG S ++S + +
Sbjct: 206 SKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWL 265
Query: 1666 PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEK 1725
R++S + S +++S + +D+KK KK + + K KK K +++K
Sbjct: 266 --RNYSQNNS--KNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSK------KVKK 315
Query: 1726 SQKHKHKKKKSKK-----------NKDKEKEKEKDDQKVK 1754
+ K KKK KK +KD+ K+ +KD +K+K
Sbjct: 316 NVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLK 355
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 97.1 bits (240), Expect = 1e-19
Identities = 203/994 (20%), Positives = 368/994 (37%), Gaps = 155/994 (15%)
Query: 810 GYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLS 869
G+++ S++ N S +R + NS + R++ G + +SR+ P+ +S
Sbjct: 130 GHSSQRTSAGSSSGTNSSGQRHDRESYNNSG-SSSRKKGQHGSEHSKSRSSSPGKPQAVS 188
Query: 870 ARDGHNQKDNTK---SKEKESENAPGDGKGNKHKKHRKR-RKGEESEGFLNPELLETSRK 925
+ + + + + SKE + +P D N R G+ S P L+ S
Sbjct: 189 SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS 248
Query: 926 S-REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984
++PT +V P D + + +E + S S + KP +K
Sbjct: 249 MLQKPTA---------YVRPM--DGQESMEPKLSSEH--YSSQSHGNSMTELKPSSKAHL 295
Query: 985 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTK---SS 1041
TK K + A G VD + S PP A KT+ +K +
Sbjct: 296 TKLKIPSQPLDAS------ASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPT 349
Query: 1042 SSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNE 1101
SQ+ TG ++ + ++K + ++ +K S+D E+ K P
Sbjct: 350 KESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGS 409
Query: 1102 KNKPLDNKGEKRKRKTEEK----------GVDKDFESSSMKISKLEVTEIVKPSPKRKME 1151
++P + E ++ G D + ESSS E ++ P P+
Sbjct: 410 NSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPE---P 466
Query: 1152 PDTEK--MDRTPEKDKISLSAPAKKIKLN-------RETGKKIGSTENISNTKEPSEKLE 1202
P T K +D K +PA + N ++ G++ G+ + ++T P E
Sbjct: 467 PPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
Query: 1203 ST------------------------SSKVKQEKVKGKVRRKVT----------GTEGSS 1228
+T S Q + GK + K G + S
Sbjct: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586
Query: 1229 STLVDYTST-------SSTGGS--PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIM 1279
T VD S+ ++T GS P K E K+ + T K + + ++ + ++I
Sbjct: 587 ETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII-- 644
Query: 1280 IQVPQSKWDKDDFES---EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---- 1332
+ S D D+ ES + K + + KP+SV + S + E++
Sbjct: 645 -ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLS 703
Query: 1333 --SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQ 1390
SEP ++ K + + + K K + KG+ K+ V EK E +K ++
Sbjct: 704 PLSEPDDRYPLIVKIDLNLLTRIPGKPYKET-EPPKGEKKN----VPEKHTREAQKQAS- 757
Query: 1391 PEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST-RASSNKDFT--------------- 1434
EK SN + + + + SK+ +T DK+ + + SSN++ +
Sbjct: 758 -EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPA 816
Query: 1435 ---PNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1491
P++D KT++ +R+ + S+ K+ K++ +K+S+S K K E K
Sbjct: 817 GPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEG----KTS 872
Query: 1492 TGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSG- 1550
+ + +PS T D+ +P TK V + + ++ EA+ K ++
Sbjct: 873 SSSKEVKEKAPSSSSNCPPSAPTLDSSKPRR-TKLVFDDRNYSADHYLQEAKKLKHNADA 931
Query: 1551 -----NKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEP 1605
K +Y L+ + +E + + + P P S + L + + A P
Sbjct: 932 LSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLA--P 989
Query: 1606 DYNESDSESNVSVKEEES----------SGNISKDLKDKIVEKAKESLDTAAVVQVGISR 1655
D +D V ES N K K + E K S + + G+
Sbjct: 990 DATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKT-LTEHLKNSYNNSQAPSPGLGS 1048
Query: 1656 NQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAES 1689
VSP S SG+ + SS+++S S
Sbjct: 1049 KAVGMPSPVSPKLSPGNSGNYSSGASSASASGSS 1082
Score = 67.4 bits (163), Expect = 1e-10
Identities = 153/803 (19%), Positives = 280/803 (34%), Gaps = 88/803 (10%)
Query: 986 KRKNDGSAVSKKENIVKPA----------KGPQEKVDGERERSPRSEPPIKKAKEETPKT 1035
++++ GS S K V PA G Q +R + S + ++
Sbjct: 96 EQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRES 155
Query: 1036 DNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEK 1095
N SSS +K G HSKS + KP + +S+ ++ + + ++
Sbjct: 156 YNNSGSSSRKK-----GQHGSEHSKS-RSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQR 209
Query: 1096 AKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTE 1155
+K P + + D+ R + + + F S M S + + KP+ + E
Sbjct: 210 SKSPRDPDANWDSPS--RVPFSSGQHSTQSFPPSLMSKSN---SMLQKPTAYVRPMDGQE 264
Query: 1156 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1215
M+ K+S + + N T K S +++ K PS+ L++++S
Sbjct: 265 SME-----PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASG--DVSCVD 317
Query: 1216 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1275
++ +++T + T + + P E + T + YN T+
Sbjct: 318 EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT--GEQKRYNPSKTSNGHQ 375
Query: 1276 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1335
M++ +D + E+ D T P S+ G +++PS+ SE
Sbjct: 376 SKSMLKDDLKLSSSEDSDGEQ-DCDKTMPRSTPGS--------NSEPSH------HNSEG 420
Query: 1336 SEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK-------NS 1388
++ + + S S S+SS+ + + E E P K N
Sbjct: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK 480
Query: 1389 TQPEKESNLDRLNEQGNFKSLSQSSKEAR---TSDKH-DSTRASSNKDFTPNRDKKTDYD 1444
P K S ++ N S KE R T + + D++ TP RD KT
Sbjct: 481 VNPHKVSPASSVDS--NIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
Query: 1445 TREYSSSKRRD--EKNELTRR----KDSPSRNKDSASGQKN---KPREERDLPKKGTGDS 1495
E +++ + + T+R K P + + +A+ + K E + + S
Sbjct: 539 GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
Query: 1496 KKSNSSPSRDRKPHDHKATYDTKRPNEETK---SVDKNPCKDREKHVLEARNNKESSGNK 1552
+ ++ RKP+ K + + RP E K S K+ K RE + ++
Sbjct: 599 SRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESES 658
Query: 1553 LLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDS 1612
L PP +Q K + +++ VKP S + +E +E D
Sbjct: 659 L-----PPSSQTPKYP---ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDD 710
Query: 1613 ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSP 1672
+ VK I +L +I K + + + + + + + S
Sbjct: 711 RYPLIVK-------IDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQA---SEKV 760
Query: 1673 SGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHK 1732
S R H + + S+ K K + K HK + K+ A E +L S
Sbjct: 761 SNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVP 820
Query: 1733 KKKSKKNKDKEKEKEKDDQKVKS 1755
K K K +KS
Sbjct: 821 SKDPKTEHGSRKRTISQSSSLKS 843
Score = 64.7 bits (156), Expect = 8e-10
Identities = 144/742 (19%), Positives = 260/742 (35%), Gaps = 95/742 (12%)
Query: 1035 TDNTKSSSSSQKDEKITGTPRKAHSKS------AKEHQETKPVKEEKVKKDYSKDVKSEK 1088
++++KS SSS + + +HS+S +KEHQ +K ++ D V
Sbjct: 171 SEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSS 230
Query: 1089 ------------LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI--- 1133
++ +KP +P+D + + + E + +S ++
Sbjct: 231 GQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPS 290
Query: 1134 SKLEVTEIVKPSPK--RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENI 1191
SK +T++ PS D +D ++ S P I +T
Sbjct: 291 SKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT---------- 340
Query: 1192 SNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK 1251
+K P ES S + K K + S S L D SS+ S + +K
Sbjct: 341 EPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDK 400
Query: 1252 TDTKRTVIKTME--EYNNDNTAPAEDVIIMIQVPQSKWDKD-DFESEEEDVKSTQPISSV 1308
T + T E +N++ + D +S D + ES D ++ +P S
Sbjct: 401 TMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSA 460
Query: 1309 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQ--KFTKDVSHEIIQHEVKSSKNSASSEK 1366
PE E P+ K Q + V+ + N SS+
Sbjct: 461 S-------------------PEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG 501
Query: 1367 GKTKDRDY----SVLEKENPEKRKNSTQPEKESNLDRLNEQGNFK----SLSQSSKEART 1418
K + R+ S + P++ ++T + + +E G + + S S+ + RT
Sbjct: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
Query: 1419 SDKHDSTRASSNKDFTPNRDKKTDYDTR-EYSSSKRRDEKNELTRRKDSPSRNKDSASGQ 1477
K +A P K + +T + +SS T+ P+ K+S S
Sbjct: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSP 621
Query: 1478 KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKN--PCK-- 1533
+ P E+ K + S+KS D D + ++ K + N P K
Sbjct: 622 R--PTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPS 679
Query: 1534 --DREKHVLEARNNKESSGNKLLYILNPPE------TQVEKEQITGQIDKSTVKPKPQLS 1585
+ E R +LL L+ P+ +++ +T K + +P
Sbjct: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
Query: 1586 HSSRLSSDLTRETDEAAFEP--------DYNESDSESNVSVK----EEESSGN---ISKD 1630
+ TRE + A E NE D+ ++ S K ++ S+G+ +++
Sbjct: 740 EKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRE 799
Query: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1690
+ K K+ L + A H S + S+S S S + +S SS S
Sbjct: 800 SSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSS 859
Query: 1691 DSKKKKKKKEKKKHKKHKKHKK 1712
+ K+KK + K + +K
Sbjct: 860 STSKQKKTEGKTSSSSKEVKEK 881
Score = 35.0 bits (79), Expect = 0.64
Identities = 112/637 (17%), Positives = 216/637 (33%), Gaps = 59/637 (9%)
Query: 1142 VKPSPKRKMEPD--TEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSE 1199
V PS K P+ ++ + + K + PA +++ + S + T S
Sbjct: 82 VPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSS 141
Query: 1200 KLESTSSKVKQEKV---KGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKR 1256
++S + + G RK G GS + S SS+ G P S + R
Sbjct: 142 SGTNSSGQRHDRESYNNSGSSSRK-KGQHGSEHS----KSRSSSPGKPQAVSSLNSSHSR 196
Query: 1257 TVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDD---FESEEEDVKSTQPISSVGKPAS 1313
+ + ND+ + + P + WD F S + +S P S + K S
Sbjct: 197 S-------HGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP-SLMSKSNS 248
Query: 1314 VIKNVSTKPSNIVKYPEKESEPSEKIQ-KFTKDVSHEIIQHEVKSSKNS-------ASSE 1365
+++ KP+ V+ + + K+ + SH E+K S + S
Sbjct: 249 MLQ----KPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQP 304
Query: 1366 KGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST 1425
+ D S +++ E + P + E F ++ S+++ +
Sbjct: 305 LDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG-EQK 363
Query: 1426 RASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNEL--TRRKDSPSRNKDSASGQKNKPRE 1483
R + +K ++ K D + SSS+ D + + T + +P N + +
Sbjct: 364 RYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADN 423
Query: 1484 ERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEAR 1543
RD +G S S + D +A ++ + E + N + + + +
Sbjct: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ-LDNWLNKVN 482
Query: 1544 NNKESSGNKLLYILNPPETQVEK----EQITGQIDKSTVKPKPQLSHSSRLSSDLTRETD 1599
+K S + + N P +Q K EQ TG T PK S + S ++
Sbjct: 483 PHKVSPASSV--DSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
Query: 1600 EAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSH 1659
E+ +S ++S+ + + K + E+ + L + V ++ +
Sbjct: 541 ESG--RGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
Query: 1660 SSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGT 1719
S + S P+ ++SK + +KK K K
Sbjct: 599 SRHKAATKGSRKPN--------------IKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
Query: 1720 EVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
E + S + + K E + K SV
Sbjct: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV 681
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 94.4 bits (233), Expect = 9e-19
Identities = 185/882 (20%), Positives = 341/882 (38%), Gaps = 149/882 (16%)
Query: 956 PMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKG----PQEKV 1011
P A+SI K ++ E+ +PKA+ T ++ + KK +K +K PQ+ V
Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE---TEKKPPPIKDSKSLTAEPQKAV 1044
Query: 1012 -DGERERSPRSEPPIKKAKEET------PKTDNTKSSSSSQ------------------- 1045
+ E+SP+ E K E P NT + +Q
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 1046 ------KDEKITG-----------------TPRKAHSKSAKEHQETKPVKEEKVKKDYSK 1082
I+G +P ++S+ + P + K++
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 1083 DVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIV 1142
++EK+ ++ K EK P+ +K+ EE ++KD K +
Sbjct: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQ----EESKLEKD---------KASALQEK 1211
Query: 1143 KPSPK-RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKL 1201
KP P+ +K+ P+ EK+ +K + P + KK+ S +E L
Sbjct: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPE-------DKKLLPEAKTSAPEEQKHDL 1264
Query: 1202 ESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKT 1261
+ ++ +EK++G+V K T ++ G+P +E T +T+
Sbjct: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME----GLPSGTPQSLPKEDDKTTKTI--- 1317
Query: 1262 MEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTK 1321
E+ TA + V + + + DK D S ++ KS Q +S G + I + +
Sbjct: 1318 KEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP-KSPQGLSDTGYSSDGISSSLGE 1376
Query: 1322 PSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKEN 1381
+++ EK+ K F+++ S S+ S+ K + S+LE +
Sbjct: 1377 IPSLIPTDEKDILKGLKKDSFSQE------------SSPSSPSDLAKLESTVLSILEAQA 1424
Query: 1382 P----EKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNR 1437
EK + TQP + S ++ +Q +SLS++ E S++ KD T +
Sbjct: 1425 STLADEKSEKKTQPHEVSP-EQPKDQEKTQSLSETL-EITISEEEIKESQEERKD-TFKK 1481
Query: 1438 DKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK 1497
D + D SSK EK+E D +R + S +++ E +P++ S
Sbjct: 1482 DSQQDIP-----SSKDHKEKSEFV--DDITTRREPYDSVEESSESENSPVPQRKRRTSVG 1534
Query: 1498 SNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL 1557
S+SS D D++ EE + K + + E N+L I
Sbjct: 1535 SSSS--------DEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEIS 1586
Query: 1558 NPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLT-------RETDEAAFEPD---- 1606
+ E+Q +KE+ G+ K T +L+ S S D + D+ AF+
Sbjct: 1587 SSTESQ-KKEETKGK-GKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELK 1644
Query: 1607 YNESDSESNVSVKEEESSG-------NISKDLKDKIVEKA---KESL---DTAAVVQVGI 1653
Y E+ S+ + + G ++ + DK ++ K SL + + +
Sbjct: 1645 YRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESL 1704
Query: 1654 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKH 1713
+ + S S H+ S + S +S +S E DS KK E K+ +K +H
Sbjct: 1705 TDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRK----ARH 1760
Query: 1714 KKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKS 1755
+ H +E S + + +++ + K++EK++E + Q+ KS
Sbjct: 1761 RPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKS 1802
Score = 73.6 bits (179), Expect = 2e-12
Identities = 158/763 (20%), Positives = 291/763 (38%), Gaps = 100/763 (13%)
Query: 1002 KPAKGPQEKVDGERERSPRSEPP---IKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAH 1058
K A PQ K+ ++E+ ++E ++K KE ++ QK E+ K
Sbjct: 1147 KTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEE-----SKLE 1201
Query: 1059 SKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTE 1118
A QE KP+ EEK + EK+ ++E+K +K P D K + +
Sbjct: 1202 KDKASALQEKKPLPEEK-----KLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA 1256
Query: 1119 EKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISL-SAPAKKIKL 1177
+ D S ++I++ ++ V P ++ + KM+ P SL K K
Sbjct: 1257 PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKT 1316
Query: 1178 NRETGKK--IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTG--TEGSSSTLVD 1233
+E + + + KE +EK + S ++ K TG ++G SS+L +
Sbjct: 1317 IKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE 1376
Query: 1234 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFE 1293
S T + K +K + + + + A E ++ I Q+ D
Sbjct: 1377 IPSLIPTDEKDILKGLKKD----SFSQESSPSSPSDLAKLESTVLSILEAQASTLAD--- 1429
Query: 1294 SEEEDVKSTQPIS-SVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQ 1352
E+ K TQP S +P K S + + E+E + S Q+ KD + Q
Sbjct: 1430 --EKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKES---QEERKDTFKKDSQ 1484
Query: 1353 HEVKSSKN----SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1408
++ SSK+ S + T+ Y +E+ + + Q ++ +++ + +
Sbjct: 1485 QDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQE 1544
Query: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS 1468
SQ S E + S+++D + + D + + + SS +K E T+ K +
Sbjct: 1545 DSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKIT 1604
Query: 1469 RNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVD 1528
K R L +K S + R HD E+ ++ D
Sbjct: 1605 AGK------------HRRLTRK---SSTSIDEDAGRRHSWHD-----------EDDEAFD 1638
Query: 1529 KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS 1588
++P L+ R K +L+ + + ++ ST+ K S
Sbjct: 1639 ESP-------ELKYRETKSQESEELVVTGGGGLRRFKTIEL-----NSTIADKYSAESSQ 1686
Query: 1589 RLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV 1648
+ +S E EP E + ES E+ S G S L A +
Sbjct: 1687 KKTSLYFDE------EP---ELEMESLTDSPEDRSRGEGSSSL------HASSFTPGTSP 1731
Query: 1649 VQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK 1708
V S SSPS S ++ R H + E DS ++++ +E+++ K +
Sbjct: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIE--DSSEEEELREEEELLKEQ 1789
Query: 1709 KHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
+ ++ E+E+ Q+ K KKSKK+KD+ + + + ++
Sbjct: 1790 EKQR---------EIEQQQR-KSSSKKSKKDKDELRAQRRRER 1822
Score = 64.3 bits (155), Expect = 1e-09
Identities = 165/820 (20%), Positives = 294/820 (35%), Gaps = 127/820 (15%)
Query: 998 ENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKA 1057
+++ KPA + V E++++P ++ K+ K P TD SSS++ K + +
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD-----IPSS 781
Query: 1058 HSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKA-KKPNEKNKPLDNKGEKRKRK 1116
+S E + T P+K + K S EK++ + KA +P +K + + G + K
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841
Query: 1117 TEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIK 1176
+K VD + K E E K K +PD + M + + +
Sbjct: 842 -GQKQVD--------PVQKKE--EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
Query: 1177 LNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTS 1236
+++ K + S + QE V GK+ +S L+
Sbjct: 891 TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI---- 946
Query: 1237 TSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKW-DKDDFESE 1295
ST G P S+ + AP + Q P S+ K ++
Sbjct: 947 --STAGQPGPHSQ-----------------SGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Query: 1296 EEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS--EKIQKFTKDVSHEIIQH 1353
KS PA+ + + VK E E +P + + T + ++
Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT 1047
Query: 1354 EV-KSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLN----------- 1401
++ KS K ++ KT + ++ K+ P + + NL N
Sbjct: 1048 KLEKSPKPESTCPLCKT---ELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 1402 -------------EQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREY 1448
+ G+ + + + + S T +SS K P + K +E
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 1449 SSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPK-KGTGDSKKSNSSPSRDRK 1507
K EK L + K++ S K ++ +EE L K K + +K +
Sbjct: 1165 ---KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLI 1221
Query: 1508 PHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKE 1567
P + K + K+P E +K P + +K + EA K S+ + + L + Q+ +E
Sbjct: 1222 PEEEKIRSEEKKPLLE----EKKPTPEDKKLLPEA---KTSAPEEQKHDLLKSQVQIAEE 1274
Query: 1568 QITGQIDKSTVK--PKPQLSHS---SRLSSDLTRETDE------------AAFEPDYNES 1610
++ G++ TV+ +PQ S L +E D+ +PD E
Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334
Query: 1611 DSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSP---- 1666
E + KE++ S D K+ + L GIS + PS+ P
Sbjct: 1335 GKEK--TEKEDDKS-----DTSSSQQPKSPQGLSDTGYSSDGISSSLG-EIPSLIPTDEK 1386
Query: 1667 -----------SRSHSPSGSQ--TRSHSSSASSAESQDSKKKKKKKEKKKHKKH---KKH 1710
S+ SPS + S+ S E+Q S +K EKK ++
Sbjct: 1387 DILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQP 1446
Query: 1711 KKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDD 1750
K +K LE + + K+ ++ KD K+ + D
Sbjct: 1447 KDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486
Score = 61.2 bits (147), Expect = 8e-09
Identities = 116/574 (20%), Positives = 223/574 (38%), Gaps = 62/574 (10%)
Query: 977 KPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTD 1036
K K KT ++ + K + V+P K EK D + + S +P + +T +
Sbjct: 1308 KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
Query: 1037 NTKSSSSSQ------KDEK--ITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEK 1088
+ SSS + DEK + G + + S +E + P K++ ++++
Sbjct: 1368 DGISSSLGEIPSLIPTDEKDILKGLKKDSFS---QESSPSSPSDLAKLESTVLSILEAQA 1424
Query: 1089 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
T +EK++K K +P + E+ K + + + + + E + IS+ E+ E +
Sbjct: 1425 STLADEKSEK---KTQPHEVSPEQPKDQEKTQSLSETLE---ITISEEEIKE------SQ 1472
Query: 1149 KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
+ DT K D + I +++ +K ++I+ +EP + +E SS+
Sbjct: 1473 EERKDTFKKDSQQD------------IPSSKDHKEKSEFVDDITTRREPYDSVEE-SSES 1519
Query: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
+ V + RR G+ S +Y S G EE+ ++ +I+ + D
Sbjct: 1520 ENSPVPQRKRRTSVGSSSSD----EYKQEDSQG-----SGEEEDFIRKQIIEMSAD--ED 1568
Query: 1269 NTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKY 1328
+ +D I Q+ + + + EE K + GK + + ST
Sbjct: 1569 ASGSEDDEFIRNQLKEISSSTESQKKEETKGKGK---ITAGKHRRLTRKSSTSIDE--DA 1623
Query: 1329 PEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNS 1388
+ S E + F D S E+ E KS ++ G R + +E + K S
Sbjct: 1624 GRRHSWHDEDDEAF--DESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYS 1681
Query: 1389 TQPEKESNLDRLNEQG--NFKSLSQSSKEARTSDKHDSTRASS-NKDFTPNRDKKTDYDT 1445
+ ++ +E+ +SL+ S ++ + S ASS +P D D+
Sbjct: 1682 AESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDS 1741
Query: 1446 REYSSSKRRDEKNE--LTRRKDSPSRNKDSASGQKNKPREERDLPK---KGTGDSKKSNS 1500
S K+ + K + R P S ++ + REE +L K K ++
Sbjct: 1742 DSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRK 1801
Query: 1501 SPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKD 1534
S S+ K + +R +T + +P +D
Sbjct: 1802 SSSKKSKKDKDELRAQRRRERPKTPPSNLSPIED 1835
Score = 43.5 bits (101), Expect = 0.002
Identities = 71/305 (23%), Positives = 101/305 (33%), Gaps = 42/305 (13%)
Query: 332 LRKQLPPPP-PPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSN 390
++ LP P PPI P P +P + P + P P+ L
Sbjct: 294 VKPSLPSPSKPPIQQPTPG-----KPPAQQPGHEKSQP---GPAKPPAQPSGLTKPLAQQ 345
Query: 391 QSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGT 450
++ PPV ++ P P + + + G + S + P A LA G
Sbjct: 346 PGTVKPPVQPPGTTKPPAQP-----LGPAKPPAQQTGSEKPSSEQPGPKA-LAQPPGVGK 399
Query: 451 SSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNK 510
+ + QV GTP L Q GP + +PG G+
Sbjct: 400 TPAQQPGPAKPPTQQV---GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK-------- 448
Query: 511 LGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYP---P 567
P QQ G+ S ++ ++ + GP+ P P PPP P
Sbjct: 449 -----IPAQQAGPGKTSAQQT-----GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 568 PPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNT 627
PP P PP Q P P Q P S PP P A S S +A +T
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPG---STKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 628 IPTTQ 632
P +Q
Sbjct: 556 KPVSQ 560
Score = 43.5 bits (101), Expect = 0.002
Identities = 98/426 (23%), Positives = 140/426 (32%), Gaps = 92/426 (21%)
Query: 231 GKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTA--- 287
GK +PP + PS+ +P + +C +C V + C EC T
Sbjct: 564 GKPLQPPTV--SPSAKQPPSQGLP-KTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
Query: 288 --------LLESDEHTCPTCHQN-----DVSPDALIANKFLRQAVNNFKNETGYTKRLRK 334
L E E C C D++P L+ A T + K
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA------PVTTTSAVSK 674
Query: 335 QLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSL 394
P P P + Q L ++P ++ PL V + H +PS +
Sbjct: 675 SSPQPQQTSPKKDAAPK---QDLSKAPEPKKPPPL---VKQPTLHGSPSAKA-------- 720
Query: 395 APPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNK----ILPAAALASEHSKGT 450
P + S PAP + SV SE+ P D K + P L S S T
Sbjct: 721 KQPPEADSLSKPAPPKEP------SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 451 S----SIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWE 506
S + + EEK TP L S Q P TG RP +
Sbjct: 775 KPDIPSSKVQSQAEEKT-------TPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 507 HSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYP 566
++S P S ++G+ + Q+ + P T +
Sbjct: 828 SK-----IISHPGP---------SSESKGQKQVDPVQKKEEPKKAQTKM----------S 863
Query: 567 PPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPW-VSSGVQTAHS 625
P P P+P G P P PG P AG +VP P P P S + ++ G T
Sbjct: 864 PKPDAKPMPKGSPTP-------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 626 NTIPTT 631
+ PTT
Sbjct: 917 KSQPTT 922
Score = 41.6 bits (96), Expect = 0.007
Identities = 82/352 (23%), Positives = 113/352 (32%), Gaps = 74/352 (21%)
Query: 302 NDVSPDALIANKF-----LRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQP 356
N +S + + NKF + + + + T K ++K+ P I PP LQ
Sbjct: 161 NALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPP-------LQQ 213
Query: 357 LMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATV 416
PI +QQ P P+ T SISS + PP +G P P P
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGT--PKSISSQQPEKIKSQPPGTGKPIQGPTQTP------ 265
Query: 417 SISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLG 476
+D+ LP AS + I + G
Sbjct: 266 --------------QTDHAKLPLQRDASRPQTKQADI--------------------VRG 291
Query: 477 QSLLHGQLIPTTGPVRINT-ARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRG 535
+S+ P+ P++ T +P +PG E S PP Q + +
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTV 349
Query: 536 RHHSERSQRTQGPSLPATPVFVPV-----PPPPLYPPPPHTLPLPPGV---PPPQFSPQF 587
+ + T+ P+ P P P P P P L PPGV P Q P
Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 588 PP----GQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPP 635
PP G P P AP TP VQ IP QA P
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-----VQQPGPGKIPAQQAGP 456
Score = 40.0 bits (92), Expect = 0.020
Identities = 33/105 (31%), Positives = 43/105 (40%), Gaps = 27/105 (25%)
Query: 549 SLPATP--------VFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP 600
SLPA P + + PPP PPPP P PP PPP PP PPP P
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPP---PPPPPPPPPP-----PPPLPPPTS---P 2433
Query: 601 PPGFPP-------APANLSTPWVSSGVQTAHSNTIPTTQAPPLSR 638
P P +P +TP + V T + + + P++R
Sbjct: 2434 KPTILPKKKLTVASPVTTATP-LFDAVTTLETTAVLRSNGLPVTR 2477
Score = 38.9 bits (89), Expect = 0.045
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 12/86 (13%)
Query: 335 QLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIP-----VTSSSTHPAPSISSLTS 389
Q PPPPPP PPP P P + P S + P ++P V S T P ++T+
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK--PTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 390 NQSSLAPPVSGNP-----SSAPAPVP 410
+++ +G P ++AP PVP
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVP 2487
Score = 38.5 bits (88), Expect = 0.058
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 558 PVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVS 617
P PPPP PPPP P PP +PPP SP+ P P +V P P + +
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPT-SPK--PTILPKKKLTVASPVTTATPLFDAVTTLE 2463
Query: 618 SGVQTAHSNTIPTTQ----APP 635
+ SN +P T+ APP
Sbjct: 2464 T-TAVLRSNGLPVTRICTTAPP 2484
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/102 (27%), Positives = 36/102 (35%), Gaps = 10/102 (9%)
Query: 535 GRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPP 594
G + +Q PS + +P P P + + P PPP P PP PP
Sbjct: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP- 2422
Query: 595 AGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPL 636
PPP PP + T + A P T A PL
Sbjct: 2423 -----PPPPLPPPTSPKPTILPKKKLTVAS----PVTTATPL 2455
Score = 35.4 bits (80), Expect = 0.49
Identities = 63/283 (22%), Positives = 103/283 (36%), Gaps = 70/283 (24%)
Query: 855 HRSRNIGSNYPEKLSARDGHN--------QKDNTKSKEKESENAPGDGKGNKHKKHRKRR 906
HR + + S++P K S R K T + + PG K K R
Sbjct: 82 HRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSR 141
Query: 907 KGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS 966
+L E + S P + E ++L + S + + P D S + S
Sbjct: 142 T----------DLKEEHKSSMMPGFLSE--VNALSAVSSVVN----KFNPFDLISDSEAS 185
Query: 967 VSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIK 1026
E K+++ K +G K E I+KP Q +++ P +P
Sbjct: 186 QEETTKKQKVVQKEQG-------------KPEGIIKPPLQQQPPKPIPKQQGPGRDPL-- 230
Query: 1027 KAKEETPKTDNTKSSSSSQKDEKI--------------TGTPRKAHSKSAKEHQETKP-- 1070
+ D T S SSQ+ EKI T TP+ H+K + ++P
Sbjct: 231 -------QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQT 283
Query: 1071 -----VKEEKVKKDYSKDVKS--EKLTTKEEKAKKP-NEKNKP 1105
V+ E VK K ++ T + A++P +EK++P
Sbjct: 284 KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Score = 35.0 bits (79), Expect = 0.64
Identities = 51/222 (22%), Positives = 86/222 (38%), Gaps = 22/222 (9%)
Query: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPN 1100
SS K + T A SKS+ + Q+T P K+ K+D SK + +K K+P
Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK---PPPLVKQPT 711
Query: 1101 EKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRT 1160
P + + + K S + K V + KP + ++P T+ + +
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD-DKPKQPKMVKPTTDLVSSS 770
Query: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRK 1220
K + P+ K++ E + + +++ +PS+ T KV K R
Sbjct: 771 SATTKPDI--PSSKVQSQAE---EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR-- 823
Query: 1221 VTGTEGSSSTLVDYTSTSSTGG-----SPVRKSEE--KTDTK 1255
S S ++ + SS PV+K EE K TK
Sbjct: 824 ----PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861
Score = 32.7 bits (73), Expect = 3.2
Identities = 79/334 (23%), Positives = 110/334 (32%), Gaps = 77/334 (23%)
Query: 333 RKQLPPPPPPIPPPRPLIQRNLQPLMR-SPISRQQDPLMIPVTSSSTHPAPSISSLTSNQ 391
++ L P P PP PL++ QP + SP ++ + P P S + PAP ++
Sbjct: 691 KQDLSKAPEPKKPP-PLVK---QPTLHGSPSAKAKQP---PEADSLSKPAPPKEPSVPSE 743
Query: 392 SSLAPPVSGNP--------------SSAPAPVPDITATVSISVHSEKSDGPFRDS----- 432
AP P SS+ PDI ++ S EK+ P +
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
Query: 433 -------------DNKILPAAALASE--HSKGTSSIAITALMEEKGY-QVPVLGTPSLLG 476
D+K +P A S+ G SS E KG QV +
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS-------ESKGQKQVDPVQKKEEPK 856
Query: 477 QSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYR-SINRG 535
++ P P+ + P G RP G V PQQ + + R S+N G
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRP------TAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 536 R-HHSERSQRTQGPSLPATPVF------------------VPVPPPPLYPPPPHTLPLPP 576
+ +SQ T +F P P P P P
Sbjct: 911 SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970
Query: 577 GVPPPQFSPQFPPGQPPPA-GYSVPPPGFPPAPA 609
PP P GQ PPA S+P APA
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPA 1004
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 94.4 bits (233), Expect = 9e-19
Identities = 185/882 (20%), Positives = 341/882 (38%), Gaps = 149/882 (16%)
Query: 956 PMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKG----PQEKV 1011
P A+SI K ++ E+ +PKA+ T ++ + KK +K +K PQ+ V
Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE---TEKKPPPIKDSKSLTAEPQKAV 1044
Query: 1012 -DGERERSPRSEPPIKKAKEET------PKTDNTKSSSSSQ------------------- 1045
+ E+SP+ E K E P NT + +Q
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 1046 ------KDEKITG-----------------TPRKAHSKSAKEHQETKPVKEEKVKKDYSK 1082
I+G +P ++S+ + P + K++
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 1083 DVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIV 1142
++EK+ ++ K EK P+ +K+ EE ++KD K +
Sbjct: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQ----EESKLEKD---------KASALQEK 1211
Query: 1143 KPSPK-RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKL 1201
KP P+ +K+ P+ EK+ +K + P + KK+ S +E L
Sbjct: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPE-------DKKLLPEAKTSAPEEQKHDL 1264
Query: 1202 ESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKT 1261
+ ++ +EK++G+V K T ++ G+P +E T +T+
Sbjct: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME----GLPSGTPQSLPKEDDKTTKTI--- 1317
Query: 1262 MEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTK 1321
E+ TA + V + + + DK D S ++ KS Q +S G + I + +
Sbjct: 1318 KEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP-KSPQGLSDTGYSSDGISSSLGE 1376
Query: 1322 PSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKEN 1381
+++ EK+ K F+++ S S+ S+ K + S+LE +
Sbjct: 1377 IPSLIPTDEKDILKGLKKDSFSQE------------SSPSSPSDLAKLESTVLSILEAQA 1424
Query: 1382 P----EKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNR 1437
EK + TQP + S ++ +Q +SLS++ E S++ KD T +
Sbjct: 1425 STLADEKSEKKTQPHEVSP-EQPKDQEKTQSLSETL-EITISEEEIKESQEERKD-TFKK 1481
Query: 1438 DKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK 1497
D + D SSK EK+E D +R + S +++ E +P++ S
Sbjct: 1482 DSQQDIP-----SSKDHKEKSEFV--DDITTRREPYDSVEESSESENSPVPQRKRRTSVG 1534
Query: 1498 SNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL 1557
S+SS D D++ EE + K + + E N+L I
Sbjct: 1535 SSSS--------DEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEIS 1586
Query: 1558 NPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLT-------RETDEAAFEPD---- 1606
+ E+Q +KE+ G+ K T +L+ S S D + D+ AF+
Sbjct: 1587 SSTESQ-KKEETKGK-GKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELK 1644
Query: 1607 YNESDSESNVSVKEEESSG-------NISKDLKDKIVEKA---KESL---DTAAVVQVGI 1653
Y E+ S+ + + G ++ + DK ++ K SL + + +
Sbjct: 1645 YRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESL 1704
Query: 1654 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKH 1713
+ + S S H+ S + S +S +S E DS KK E K+ +K +H
Sbjct: 1705 TDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRK----ARH 1760
Query: 1714 KKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKS 1755
+ H +E S + + +++ + K++EK++E + Q+ KS
Sbjct: 1761 RPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKS 1802
Score = 73.6 bits (179), Expect = 2e-12
Identities = 158/763 (20%), Positives = 291/763 (38%), Gaps = 100/763 (13%)
Query: 1002 KPAKGPQEKVDGERERSPRSEPP---IKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAH 1058
K A PQ K+ ++E+ ++E ++K KE ++ QK E+ K
Sbjct: 1147 KTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEE-----SKLE 1201
Query: 1059 SKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTE 1118
A QE KP+ EEK + EK+ ++E+K +K P D K + +
Sbjct: 1202 KDKASALQEKKPLPEEK-----KLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA 1256
Query: 1119 EKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISL-SAPAKKIKL 1177
+ D S ++I++ ++ V P ++ + KM+ P SL K K
Sbjct: 1257 PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKT 1316
Query: 1178 NRETGKK--IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTG--TEGSSSTLVD 1233
+E + + + KE +EK + S ++ K TG ++G SS+L +
Sbjct: 1317 IKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE 1376
Query: 1234 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFE 1293
S T + K +K + + + + A E ++ I Q+ D
Sbjct: 1377 IPSLIPTDEKDILKGLKKD----SFSQESSPSSPSDLAKLESTVLSILEAQASTLAD--- 1429
Query: 1294 SEEEDVKSTQPIS-SVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQ 1352
E+ K TQP S +P K S + + E+E + S Q+ KD + Q
Sbjct: 1430 --EKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKES---QEERKDTFKKDSQ 1484
Query: 1353 HEVKSSKN----SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1408
++ SSK+ S + T+ Y +E+ + + Q ++ +++ + +
Sbjct: 1485 QDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQE 1544
Query: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS 1468
SQ S E + S+++D + + D + + + SS +K E T+ K +
Sbjct: 1545 DSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKIT 1604
Query: 1469 RNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVD 1528
K R L +K S + R HD E+ ++ D
Sbjct: 1605 AGK------------HRRLTRK---SSTSIDEDAGRRHSWHD-----------EDDEAFD 1638
Query: 1529 KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS 1588
++P L+ R K +L+ + + ++ ST+ K S
Sbjct: 1639 ESP-------ELKYRETKSQESEELVVTGGGGLRRFKTIEL-----NSTIADKYSAESSQ 1686
Query: 1589 RLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV 1648
+ +S E EP E + ES E+ S G S L A +
Sbjct: 1687 KKTSLYFDE------EP---ELEMESLTDSPEDRSRGEGSSSL------HASSFTPGTSP 1731
Query: 1649 VQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK 1708
V S SSPS S ++ R H + E DS ++++ +E+++ K +
Sbjct: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIE--DSSEEEELREEEELLKEQ 1789
Query: 1709 KHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
+ ++ E+E+ Q+ K KKSKK+KD+ + + + ++
Sbjct: 1790 EKQR---------EIEQQQR-KSSSKKSKKDKDELRAQRRRER 1822
Score = 64.3 bits (155), Expect = 1e-09
Identities = 165/820 (20%), Positives = 294/820 (35%), Gaps = 127/820 (15%)
Query: 998 ENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKA 1057
+++ KPA + V E++++P ++ K+ K P TD SSS++ K + +
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD-----IPSS 781
Query: 1058 HSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKA-KKPNEKNKPLDNKGEKRKRK 1116
+S E + T P+K + K S EK++ + KA +P +K + + G + K
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841
Query: 1117 TEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIK 1176
+K VD + K E E K K +PD + M + + +
Sbjct: 842 -GQKQVD--------PVQKKE--EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
Query: 1177 LNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTS 1236
+++ K + S + QE V GK+ +S L+
Sbjct: 891 TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI---- 946
Query: 1237 TSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKW-DKDDFESE 1295
ST G P S+ + AP + Q P S+ K ++
Sbjct: 947 --STAGQPGPHSQ-----------------SGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Query: 1296 EEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS--EKIQKFTKDVSHEIIQH 1353
KS PA+ + + VK E E +P + + T + ++
Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT 1047
Query: 1354 EV-KSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLN----------- 1401
++ KS K ++ KT + ++ K+ P + + NL N
Sbjct: 1048 KLEKSPKPESTCPLCKT---ELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 1402 -------------EQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREY 1448
+ G+ + + + + S T +SS K P + K +E
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 1449 SSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPK-KGTGDSKKSNSSPSRDRK 1507
K EK L + K++ S K ++ +EE L K K + +K +
Sbjct: 1165 ---KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLI 1221
Query: 1508 PHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKE 1567
P + K + K+P E +K P + +K + EA K S+ + + L + Q+ +E
Sbjct: 1222 PEEEKIRSEEKKPLLE----EKKPTPEDKKLLPEA---KTSAPEEQKHDLLKSQVQIAEE 1274
Query: 1568 QITGQIDKSTVK--PKPQLSHS---SRLSSDLTRETDE------------AAFEPDYNES 1610
++ G++ TV+ +PQ S L +E D+ +PD E
Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334
Query: 1611 DSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSP---- 1666
E + KE++ S D K+ + L GIS + PS+ P
Sbjct: 1335 GKEK--TEKEDDKS-----DTSSSQQPKSPQGLSDTGYSSDGISSSLG-EIPSLIPTDEK 1386
Query: 1667 -----------SRSHSPSGSQ--TRSHSSSASSAESQDSKKKKKKKEKKKHKKH---KKH 1710
S+ SPS + S+ S E+Q S +K EKK ++
Sbjct: 1387 DILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQP 1446
Query: 1711 KKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDD 1750
K +K LE + + K+ ++ KD K+ + D
Sbjct: 1447 KDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486
Score = 61.2 bits (147), Expect = 8e-09
Identities = 116/574 (20%), Positives = 223/574 (38%), Gaps = 62/574 (10%)
Query: 977 KPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTD 1036
K K KT ++ + K + V+P K EK D + + S +P + +T +
Sbjct: 1308 KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
Query: 1037 NTKSSSSSQ------KDEK--ITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEK 1088
+ SSS + DEK + G + + S +E + P K++ ++++
Sbjct: 1368 DGISSSLGEIPSLIPTDEKDILKGLKKDSFS---QESSPSSPSDLAKLESTVLSILEAQA 1424
Query: 1089 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
T +EK++K K +P + E+ K + + + + + E + IS+ E+ E +
Sbjct: 1425 STLADEKSEK---KTQPHEVSPEQPKDQEKTQSLSETLE---ITISEEEIKE------SQ 1472
Query: 1149 KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
+ DT K D + I +++ +K ++I+ +EP + +E SS+
Sbjct: 1473 EERKDTFKKDSQQD------------IPSSKDHKEKSEFVDDITTRREPYDSVEE-SSES 1519
Query: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
+ V + RR G+ S +Y S G EE+ ++ +I+ + D
Sbjct: 1520 ENSPVPQRKRRTSVGSSSSD----EYKQEDSQG-----SGEEEDFIRKQIIEMSAD--ED 1568
Query: 1269 NTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKY 1328
+ +D I Q+ + + + EE K + GK + + ST
Sbjct: 1569 ASGSEDDEFIRNQLKEISSSTESQKKEETKGKGK---ITAGKHRRLTRKSSTSIDE--DA 1623
Query: 1329 PEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNS 1388
+ S E + F D S E+ E KS ++ G R + +E + K S
Sbjct: 1624 GRRHSWHDEDDEAF--DESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYS 1681
Query: 1389 TQPEKESNLDRLNEQG--NFKSLSQSSKEARTSDKHDSTRASS-NKDFTPNRDKKTDYDT 1445
+ ++ +E+ +SL+ S ++ + S ASS +P D D+
Sbjct: 1682 AESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDS 1741
Query: 1446 REYSSSKRRDEKNE--LTRRKDSPSRNKDSASGQKNKPREERDLPK---KGTGDSKKSNS 1500
S K+ + K + R P S ++ + REE +L K K ++
Sbjct: 1742 DSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRK 1801
Query: 1501 SPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKD 1534
S S+ K + +R +T + +P +D
Sbjct: 1802 SSSKKSKKDKDELRAQRRRERPKTPPSNLSPIED 1835
Score = 43.5 bits (101), Expect = 0.002
Identities = 71/305 (23%), Positives = 101/305 (33%), Gaps = 42/305 (13%)
Query: 332 LRKQLPPPP-PPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSN 390
++ LP P PPI P P +P + P + P P+ L
Sbjct: 294 VKPSLPSPSKPPIQQPTPG-----KPPAQQPGHEKSQP---GPAKPPAQPSGLTKPLAQQ 345
Query: 391 QSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGT 450
++ PPV ++ P P + + + G + S + P A LA G
Sbjct: 346 PGTVKPPVQPPGTTKPPAQP-----LGPAKPPAQQTGSEKPSSEQPGPKA-LAQPPGVGK 399
Query: 451 SSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNK 510
+ + QV GTP L Q GP + +PG G+
Sbjct: 400 TPAQQPGPAKPPTQQV---GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK-------- 448
Query: 511 LGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYP---P 567
P QQ G+ S ++ ++ + GP+ P P PPP P
Sbjct: 449 -----IPAQQAGPGKTSAQQT-----GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 568 PPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNT 627
PP P PP Q P P Q P S PP P A S S +A +T
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPG---STKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 628 IPTTQ 632
P +Q
Sbjct: 556 KPVSQ 560
Score = 43.5 bits (101), Expect = 0.002
Identities = 98/426 (23%), Positives = 140/426 (32%), Gaps = 92/426 (21%)
Query: 231 GKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTA--- 287
GK +PP + PS+ +P + +C +C V + C EC T
Sbjct: 564 GKPLQPPTV--SPSAKQPPSQGLP-KTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
Query: 288 --------LLESDEHTCPTCHQN-----DVSPDALIANKFLRQAVNNFKNETGYTKRLRK 334
L E E C C D++P L+ A T + K
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA------PVTTTSAVSK 674
Query: 335 QLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSL 394
P P P + Q L ++P ++ PL V + H +PS +
Sbjct: 675 SSPQPQQTSPKKDAAPK---QDLSKAPEPKKPPPL---VKQPTLHGSPSAKA-------- 720
Query: 395 APPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNK----ILPAAALASEHSKGT 450
P + S PAP + SV SE+ P D K + P L S S T
Sbjct: 721 KQPPEADSLSKPAPPKEP------SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 451 S----SIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWE 506
S + + EEK TP L S Q P TG RP +
Sbjct: 775 KPDIPSSKVQSQAEEKT-------TPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 507 HSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYP 566
++S P S ++G+ + Q+ + P T +
Sbjct: 828 SK-----IISHPGP---------SSESKGQKQVDPVQKKEEPKKAQTKM----------S 863
Query: 567 PPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPW-VSSGVQTAHS 625
P P P+P G P P PG P AG +VP P P P S + ++ G T
Sbjct: 864 PKPDAKPMPKGSPTP-------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 626 NTIPTT 631
+ PTT
Sbjct: 917 KSQPTT 922
Score = 41.6 bits (96), Expect = 0.007
Identities = 82/352 (23%), Positives = 113/352 (32%), Gaps = 74/352 (21%)
Query: 302 NDVSPDALIANKF-----LRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQP 356
N +S + + NKF + + + + T K ++K+ P I PP LQ
Sbjct: 161 NALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPP-------LQQ 213
Query: 357 LMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATV 416
PI +QQ P P+ T SISS + PP +G P P P
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGT--PKSISSQQPEKIKSQPPGTGKPIQGPTQTP------ 265
Query: 417 SISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLG 476
+D+ LP AS + I + G
Sbjct: 266 --------------QTDHAKLPLQRDASRPQTKQADI--------------------VRG 291
Query: 477 QSLLHGQLIPTTGPVRINT-ARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRG 535
+S+ P+ P++ T +P +PG E S PP Q + +
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTV 349
Query: 536 RHHSERSQRTQGPSLPATPVFVPV-----PPPPLYPPPPHTLPLPPGV---PPPQFSPQF 587
+ + T+ P+ P P P P P P L PPGV P Q P
Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 588 PP----GQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPP 635
PP G P P AP TP VQ IP QA P
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-----VQQPGPGKIPAQQAGP 456
Score = 40.0 bits (92), Expect = 0.020
Identities = 33/105 (31%), Positives = 43/105 (40%), Gaps = 27/105 (25%)
Query: 549 SLPATP--------VFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP 600
SLPA P + + PPP PPPP P PP PPP PP PPP P
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPP---PPPPPPPPPP-----PPPLPPPTS---P 2433
Query: 601 PPGFPP-------APANLSTPWVSSGVQTAHSNTIPTTQAPPLSR 638
P P +P +TP + V T + + + P++R
Sbjct: 2434 KPTILPKKKLTVASPVTTATP-LFDAVTTLETTAVLRSNGLPVTR 2477
Score = 38.9 bits (89), Expect = 0.045
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 12/86 (13%)
Query: 335 QLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIP-----VTSSSTHPAPSISSLTS 389
Q PPPPPP PPP P P + P S + P ++P V S T P ++T+
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK--PTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 390 NQSSLAPPVSGNP-----SSAPAPVP 410
+++ +G P ++AP PVP
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVP 2487
Score = 38.5 bits (88), Expect = 0.058
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 558 PVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVS 617
P PPPP PPPP P PP +PPP SP+ P P +V P P + +
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPT-SPK--PTILPKKKLTVASPVTTATPLFDAVTTLE 2463
Query: 618 SGVQTAHSNTIPTTQ----APP 635
+ SN +P T+ APP
Sbjct: 2464 T-TAVLRSNGLPVTRICTTAPP 2484
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/102 (27%), Positives = 36/102 (35%), Gaps = 10/102 (9%)
Query: 535 GRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPP 594
G + +Q PS + +P P P + + P PPP P PP PP
Sbjct: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP- 2422
Query: 595 AGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPL 636
PPP PP + T + A P T A PL
Sbjct: 2423 -----PPPPLPPPTSPKPTILPKKKLTVAS----PVTTATPL 2455
Score = 35.4 bits (80), Expect = 0.49
Identities = 63/283 (22%), Positives = 103/283 (36%), Gaps = 70/283 (24%)
Query: 855 HRSRNIGSNYPEKLSARDGHN--------QKDNTKSKEKESENAPGDGKGNKHKKHRKRR 906
HR + + S++P K S R K T + + PG K K R
Sbjct: 82 HRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSR 141
Query: 907 KGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS 966
+L E + S P + E ++L + S + + P D S + S
Sbjct: 142 T----------DLKEEHKSSMMPGFLSE--VNALSAVSSVVN----KFNPFDLISDSEAS 185
Query: 967 VSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIK 1026
E K+++ K +G K E I+KP Q +++ P +P
Sbjct: 186 QEETTKKQKVVQKEQG-------------KPEGIIKPPLQQQPPKPIPKQQGPGRDPL-- 230
Query: 1027 KAKEETPKTDNTKSSSSSQKDEKI--------------TGTPRKAHSKSAKEHQETKP-- 1070
+ D T S SSQ+ EKI T TP+ H+K + ++P
Sbjct: 231 -------QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQT 283
Query: 1071 -----VKEEKVKKDYSKDVKS--EKLTTKEEKAKKP-NEKNKP 1105
V+ E VK K ++ T + A++P +EK++P
Sbjct: 284 KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Score = 35.0 bits (79), Expect = 0.64
Identities = 51/222 (22%), Positives = 86/222 (38%), Gaps = 22/222 (9%)
Query: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPN 1100
SS K + T A SKS+ + Q+T P K+ K+D SK + +K K+P
Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK---PPPLVKQPT 711
Query: 1101 EKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRT 1160
P + + + K S + K V + KP + ++P T+ + +
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD-DKPKQPKMVKPTTDLVSSS 770
Query: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRK 1220
K + P+ K++ E + + +++ +PS+ T KV K R
Sbjct: 771 SATTKPDI--PSSKVQSQAE---EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR-- 823
Query: 1221 VTGTEGSSSTLVDYTSTSSTGG-----SPVRKSEE--KTDTK 1255
S S ++ + SS PV+K EE K TK
Sbjct: 824 ----PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861
Score = 32.7 bits (73), Expect = 3.2
Identities = 79/334 (23%), Positives = 110/334 (32%), Gaps = 77/334 (23%)
Query: 333 RKQLPPPPPPIPPPRPLIQRNLQPLMR-SPISRQQDPLMIPVTSSSTHPAPSISSLTSNQ 391
++ L P P PP PL++ QP + SP ++ + P P S + PAP ++
Sbjct: 691 KQDLSKAPEPKKPP-PLVK---QPTLHGSPSAKAKQP---PEADSLSKPAPPKEPSVPSE 743
Query: 392 SSLAPPVSGNP--------------SSAPAPVPDITATVSISVHSEKSDGPFRDS----- 432
AP P SS+ PDI ++ S EK+ P +
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
Query: 433 -------------DNKILPAAALASE--HSKGTSSIAITALMEEKGY-QVPVLGTPSLLG 476
D+K +P A S+ G SS E KG QV +
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS-------ESKGQKQVDPVQKKEEPK 856
Query: 477 QSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYR-SINRG 535
++ P P+ + P G RP G V PQQ + + R S+N G
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRP------TAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 536 R-HHSERSQRTQGPSLPATPVF------------------VPVPPPPLYPPPPHTLPLPP 576
+ +SQ T +F P P P P P
Sbjct: 911 SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970
Query: 577 GVPPPQFSPQFPPGQPPPA-GYSVPPPGFPPAPA 609
PP P GQ PPA S+P APA
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPA 1004
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 92.4 bits (228), Expect = 3e-18
Identities = 167/770 (21%), Positives = 287/770 (37%), Gaps = 119/770 (15%)
Query: 996 KKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE---TPKTDNTKSSSSSQKDEKITG 1052
K+ I + +K D ++++ + E + K E +P+ ++S S ++ +
Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRR 191
Query: 1053 TPRKAHSKSAKEHQETK-----PVKEEKVKKDYSKDVKSEKLTTKEE-------KAKKPN 1100
+++HS+S + +++ P K+EK + VK ++ + +E K KP
Sbjct: 192 ERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE 251
Query: 1101 EKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRT 1160
+P + EK +K +EK +K S + T PS R P R+
Sbjct: 252 PIPEPKEPSPEKNSKKEKEK--EKTRPRSRSRSKSRSRTRSRSPSHTR---PRRRHRSRS 306
Query: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRK 1220
+P ++ R T + P + + S V++ RR
Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPR---------RMPPPPRHRRSRSPVRRR------RRS 351
Query: 1221 VTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMI 1280
GSSS+ S S P R S T+R +P
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP------- 404
Query: 1281 QVPQSKWDKDDFESEEEDVKSTQPISSVGKPA-SVIKNVSTK----PSNIVKYPEKESEP 1335
P K + + ++ S G+ + V K+ T+ PS K + E
Sbjct: 405 ATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSE 464
Query: 1336 SEKIQKFTKDVSHEIIQ--HEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEK 1393
SE+ K K + + +Q + + +SS+ G + S E E P++ K
Sbjct: 465 SEE-DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS-----SSSEDERPKR-----SHVK 513
Query: 1394 ESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKR 1453
+ R +S S S R K S R + +P ++ + +R
Sbjct: 514 NGEVGRRRRHSPSRSASPS---PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR 570
Query: 1454 RDEKNELTRRKDSPSRNKDSASGQKNKPREERDL-----PKKGTGD---SKKSNSSPSRD 1505
R RR SP + S S ++ P +R PK+ T K +SPS
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS-- 628
Query: 1506 RKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVE 1565
P + + P + + V K R L +++ K SS ++ P+
Sbjct: 629 --PPPKRRVSHSPPPKQRSSPVTK-----RRSPSLSSKHRKGSSPSRSTREARSPQPN-- 679
Query: 1566 KEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSG 1625
+ + P+P+ +S + R A+ P +S S S ++
Sbjct: 680 --------KRHSPSPRPRAPQTSSSPPPVRR---GASSSPQRRQSPSPSTRPIR------ 722
Query: 1626 NISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHS------------SP--SVSPSRSHS 1671
+S+ + K ++KA S +V +V SR+ S S SP S SPS + S
Sbjct: 723 RVSRTPEPKKIKKA-ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS 781
Query: 1672 PSGSQTRSHSSSAS-----SAESQDSKKKKKKKEKKKHKKHKKHKKHKKH 1716
P+ ++ S + S +++ + KKKKKK+ KKHKK KKHKKHKKH
Sbjct: 782 PAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKH 831
Score = 85.1 bits (209), Expect = 5e-16
Identities = 150/713 (21%), Positives = 244/713 (34%), Gaps = 137/713 (19%)
Query: 638 REEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSP 697
+ E R RR K S SP SS R S SRS R++S S S + P
Sbjct: 165 KRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 698 ----------------------------------PYPRRGRGKSRNY-----RSRSRSHG 718
P P + K + RSRSRS
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
Query: 719 YHRSRSRSP----PYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDM 774
R+RSRSP P RR+ SRSRS R SP +R P+ T R +PPP
Sbjct: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP------RRMPPP--- 335
Query: 775 KAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPL 834
R R P + R +G+ S++R P++ P
Sbjct: 336 ----PRHRRSRSPVRRRRRS--------------SASLSGSSSSSSSSRSRSPPKK--PP 375
Query: 835 NIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDG 894
+SP + RR R R + + ++++ +PG
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
Query: 895 KGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRD 954
G K KH+ K E P +E S EE+K + S R
Sbjct: 436 SG-KVTKHKGTEKRESPSPAPKPRKVELSES-------EEDKGGKMAAADSVQQRRQYRR 487
Query: 955 EPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGE 1014
+ + S + S S +D+R + G+ +R+ + S + K K + G
Sbjct: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR--GR 545
Query: 1015 RERSPRSEPPIKKAKEETP---------KTDNTKSSSSSQKDEKITGTPRKAHSKSAKEH 1065
R RSP S PP ++ + +P T + + S + + +PR+ + +
Sbjct: 546 RRRSP-SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY 604
Query: 1066 QETKPVKEEKV----------------KKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNK 1109
+ P K K+ S ++ ++ K + P+ +K K
Sbjct: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK--HRK 662
Query: 1110 GEKRKRKTEEKGVDKDFESSS---------MKISKLEVTEIVKPSPKRKMEPD-----TE 1155
G R T E + + S S V SP+R+ P
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIR 722
Query: 1156 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1215
++ RTPE KI +A + ++ +++ S+ ++S + EP+ K K
Sbjct: 723 RVSRTPEPKKIKKAASP-----SPQSVRRVSSSRSVSGSPEPAAK--------KPPAPPS 769
Query: 1216 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
V+ + T S + V + + SP R S+++ K+ K +++ D
Sbjct: 770 PVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD 822
Score = 64.7 bits (156), Expect = 8e-10
Identities = 150/800 (18%), Positives = 288/800 (36%), Gaps = 81/800 (10%)
Query: 862 SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEE-----SEGFLN 916
S+ ++ +R +K + S + S + K + + R R K +
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
Query: 917 PELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDK-RER 975
PEL E S K +EP+ E T + +P + + P EP ++ + EK + R R
Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVP-KPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR 279
Query: 976 DKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKT 1035
+ K++ R + ++ + P+ + R SPR P ++ P
Sbjct: 280 SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM---PPPP 336
Query: 1036 DNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEK 1095
+ +S S ++ + + + + S S+ + P K K+ S K+ +L+
Sbjct: 337 RHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP--KRTSSPPRKTRRLSPSASP 394
Query: 1096 AKKPNEKNKPLDNKGEKR-------KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
++ + + P + R +T + V +S K++K + TE + SP
Sbjct: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTE-KRESPSP 453
Query: 1149 KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
+P ++ + E+DK A A ++ R+ ++ + + S + SE S V
Sbjct: 454 APKPRKVELSES-EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
Query: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
K +V G+ RR S S TS G R+S T+R +
Sbjct: 513 KNGEV-GRRRRHSPSRSASPSPRKRQKETSPRGRR--RRSPSPPPTRRRRSPSPAPPPRR 569
Query: 1269 NTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKY 1328
P P + + + PI P+ K + P
Sbjct: 570 RRTPTPPPRRRTPSPPPR------RRSPSPRRYSPPIQRRYSPSPPPKRRTASPP---PP 620
Query: 1329 PEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENP---EKR 1385
P++ + PS + + VSH K R V ++ +P K
Sbjct: 621 PKRRASPSPPPK---RRVSH-----------------SPPPKQRSSPVTKRRSPSLSSKH 660
Query: 1386 KNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDT 1445
+ + P + + R + S S + +TS R ++ +P R + T
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS--SPQRRQSPSPST 718
Query: 1446 REYSSSKRRDEKNELTR-RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSR 1504
R R E ++ + SP + +S + E K S + SPS
Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778
Query: 1505 DRKP--HDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET 1562
+ P KA T P+ S D+ ++K + ++ K+ K
Sbjct: 779 NWSPAVPVKKAKSPTPSPSPPRNS-DQEGGGKKKKKKKDKKHKKDKKHKK--------HK 829
Query: 1563 QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE 1622
+ +KE+ + V P + + ++ L +E AA EP E++SE+ E+
Sbjct: 830 KHKKEKAVAAAAAAAVTP----AAIAAATTTLAQEEPVAAPEPK-KETESEA------ED 878
Query: 1623 SSGNISKDLKDKIVEKAKES 1642
+ ++ K L++K + +++
Sbjct: 879 NLDDLEKHLREKALRSMRKA 898
Score = 61.6 bits (148), Expect = 6e-09
Identities = 136/586 (23%), Positives = 190/586 (32%), Gaps = 110/586 (18%)
Query: 517 PPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPP 576
PP R RS R R S + S +P PP PP T L P
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPP--KKPPKRTSSPPRKTRRLSP 390
Query: 577 GVPPPQFSPQ-FPPGQPPPAGYSVPPP--GFPPAPANLS-TPWVSSGVQTAHSNT----- 627
PP+ + PP PPP P P + +S +P +SG T H T
Sbjct: 391 SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450
Query: 628 ---IPTTQAPPLSREEFYR----------EQRRLKEESKSPYSGSSYSRSSYTYSKSRSG 674
P + LS E + +QRR S S S SS + +
Sbjct: 451 PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
Query: 675 STRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHS 734
++ R S SRS S SP R R K + R R R RS SPP R
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSP----RKRQKETSPRGRRR-------RSPSPPPTR--- 556
Query: 735 RSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYR 794
R RSP P +R P R PPP R P +
Sbjct: 557 RRRSPSP--APPPRRRRTPTPPPRRR-----TPSPPPRR-----------RSPSPRRYSP 598
Query: 795 EWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRG-RREDYVGGQ 853
+R+Y P P R SP P R SP RR +
Sbjct: 599 PIQRRY---------------SPSPPPKRRTASPPP--PPKRRASPSPPPKRRVSHSPPP 641
Query: 854 SHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEG 913
RS + LS++ ++K ++ S+ +P K +H + R + S
Sbjct: 642 KQRSSPVTKRRSPSLSSK---HRKGSSPSRSTREARSPQPNK--RHSPSPRPRAPQTSSS 696
Query: 914 FLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKR 973
P V + S P R + + + VS +
Sbjct: 697 ---------------PPPVRRGASSS-----------PQRRQSPSPSTRPIRRVSRTPEP 730
Query: 974 ERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSE----PPIKKAK 1029
++ K A + S+ S + AK P + +SP + P+KKAK
Sbjct: 731 KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK 790
Query: 1030 EETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEK 1075
TP ++S +K K H K K+H++ K K+EK
Sbjct: 791 SPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD-KKHKKHKKHKKEK 835
Score = 57.4 bits (137), Expect = 1e-07
Identities = 135/605 (22%), Positives = 201/605 (33%), Gaps = 134/605 (22%)
Query: 339 PPPPIPPPRPLIQRNLQPLMR--------------SPISRQQDPLMIPVTSSSTHP---- 380
PP +PPP P +R+ P+ R S SR + P P +S+ P
Sbjct: 328 PPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386
Query: 381 --APSISSLTSNQSSLAPPVSGNPSSAPAPVP---DITATVSISVHSEKSDGPF---RDS 432
+PS S + +PP + P + +P P + T +SV ++ G + +
Sbjct: 387 RLSPSASP-PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
Query: 433 DNKILPAAA--------LASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQL 484
+ + P+ A SE KG A ++ + + Y+ + S G S
Sbjct: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
Query: 485 IPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQR 544
P V+ G G + SP + R+ E S R +R
Sbjct: 506 RPKRSHVK-------NGEVGRRRRHSPSRSASPSPRKRQKETS------------PRGRR 546
Query: 545 TQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGF 604
+ PS P P P P PP P PP P+ PPP S P +
Sbjct: 547 RRSPSPP--PTRRRRSPSPAPPPRRRRTPTPP--------PRRRTPSPPPRRRSPSPRRY 596
Query: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSS---Y 661
P +P +TA + PP R +R S P SS
Sbjct: 597 SPPIQRRYSPSPPPKRRTA------SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650
Query: 662 SRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHR 721
RS SK R GS+ SRS + S ++ +S SP R R+ +
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP-------------RPRA-----PQ 692
Query: 722 SRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRS 781
+ S PP RR S SPQ + SP+ R + R P P +K S
Sbjct: 693 TSSSPPPVRR--GASSSPQRRQSPSPSTRPI----------RRVSRTPEPKKIKKAASPS 740
Query: 782 VDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPF 841
+ + + P P+A + P P+ SP
Sbjct: 741 -------------------PQSVRRVSSSRSVSGSPEPAAKKPPAPPS---PVQ-SQSPS 777
Query: 842 TRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKK 901
T V + S P R+ + K K+K+ + D K KHKK
Sbjct: 778 TNWSPAVPV-------KKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKK 830
Query: 902 HRKRR 906
H+K +
Sbjct: 831 HKKEK 835
Score = 51.6 bits (122), Expect = 7e-06
Identities = 127/639 (19%), Positives = 217/639 (33%), Gaps = 105/639 (16%)
Query: 629 PTTQAPPLSREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRS 688
P + PP R R R + S + SGSS S S SRS S + R+ S
Sbjct: 328 PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS-----SSSSRSRSPPKKPPKRTSSPP 382
Query: 689 H-SRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSP 747
+R S S PRR R R ++R P + +R+R + SP
Sbjct: 383 RKTRRLSPSASPPRR--------RHRPSPPATPPPKTRHSPTPQQSNRTRKSRV--SVSP 432
Query: 748 NKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYR-------EWERKY 800
+ + G+ + RE P P A R V+ + E + + + R+Y
Sbjct: 433 GRTS---GKVTKHKGTEKRESPSP----APKPRKVELSESEEDKGGKMAAADSVQQRRQY 485
Query: 801 REWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNI 860
R + + + S++ E+ P+R +++N R RR H
Sbjct: 486 RR------QNQQSSSDSGSSSSSEDERPKR---SHVKNGEVGRRRR--------HSPSRS 528
Query: 861 GSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELL 920
S P K ++ + + + + S + P R+RR +P
Sbjct: 529 ASPSPRK------RQKETSPRGRRRRSPSPP---------PTRRRR---------SPSPA 564
Query: 921 ETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKA 980
R+ R PT +T S P R +P R P +R P
Sbjct: 565 PPPRRRRTPTPPPRRRTPS--PPPRRRSPSPRRYSP------------PIQRRYSPSPPP 610
Query: 981 KGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKS 1040
K + S + P+ P+ +V RS P K+ S
Sbjct: 611 K------RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664
Query: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPN 1100
S S E + P K HS S + V++ S + ++ + P+
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS---------SSPQRRQSPS 715
Query: 1101 EKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRT 1160
+P+ + K +K +S S V+ +P+ K+ P + ++
Sbjct: 716 PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS 775
Query: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEK--VKGKVR 1218
P + S + P KK K + +++ K+ +K + K K+ K K K
Sbjct: 776 PSTN-WSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKE 834
Query: 1219 RKVTGTEGSSST--LVDYTSTSSTGGSPVRKSEEKTDTK 1255
+ V ++ T + +T+ PV E K +T+
Sbjct: 835 KAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETE 873
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 91.3 bits (225), Expect = 8e-18
Identities = 146/676 (21%), Positives = 261/676 (38%), Gaps = 109/676 (16%)
Query: 954 DEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDG 1013
D +DA + + ++E K K K K K+K D +++I+K + + G
Sbjct: 16 DIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQD----FDEDDILKELEELSLEAQG 71
Query: 1014 -ERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVK 1072
+ +R + P + +EE D K +K + K +K + KP
Sbjct: 72 IKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKV 131
Query: 1073 EEKVKKDYSKDVKSEKLTTKEE-KAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSM 1131
E D D KL K + KA+K N+K + + K+ E ++ ES
Sbjct: 132 EMYSGSDDDDDF--NKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDE 189
Query: 1132 KISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKD-KISLSAPAKKIKLNRETGK------- 1183
L+ + K + K K P+ E + + KI A K K RE K
Sbjct: 190 SDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAK 249
Query: 1184 --KIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTG 1241
K+ E + K+ K + + K ++E VK KV T TG
Sbjct: 250 LRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV-------------------TVDTG 290
Query: 1242 GSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKS 1301
P SEEK +T T E +N+ +D + K +K++ E E++ S
Sbjct: 291 VIPA--SEEKAET-----PTAAEDDNEGDKKKKD------KKKKKGEKEEKEKEKKKGPS 337
Query: 1302 TQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNS 1361
+ ++ + + +K + ++ E E+I++
Sbjct: 338 KATVKAMQEALAKLKEEEER---------QKREEEERIKRL------------------- 369
Query: 1362 ASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDK 1421
E+ + K ++ LE+E E++K Q EKE +RL ++G K L++S +EAR +
Sbjct: 370 ---EELEAKRKEEERLEQEKRERKK---QKEKERK-ERLKKEG--KLLTKSQREARARAE 420
Query: 1422 HDSTRASSNKDFTPNRD----KKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQ 1477
+ P++D K+ Y+ ++ ++ E E++ + + + G
Sbjct: 421 ATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV 480
Query: 1478 KNK--------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDK 1529
K P EE D G D ++ +S K +K + K EE + ++
Sbjct: 481 PEKEETPPPVEPEEEEDTEDAGL-DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEE 539
Query: 1530 NPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQ-IDKSTVKPKPQLSHSS 1588
+D E E ES G++ + + +V E+ +G+ +DK KP ++S S
Sbjct: 540 EEEEDEESEE-EEEEEGESEGSE----GDEEDEKVSDEKDSGKTLDK---KPSKEMSSDS 591
Query: 1589 RLSSDLTRETDEAAFE 1604
SD R +E A++
Sbjct: 592 EYDSDDDRTKEERAYD 607
Score = 87.4 bits (215), Expect = 1e-16
Identities = 138/619 (22%), Positives = 247/619 (39%), Gaps = 70/619 (11%)
Query: 888 ENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRD 947
E P KG K KK +K++ +E + L E S E G++ ++ +++ V P+ +
Sbjct: 34 EQEPQKSKGKK-KKEKKKQDFDEDD-----ILKELEELSLEAQGIKADR-ETVAVKPTEN 86
Query: 948 DATPV--RDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKN----DGSAVSKKEN-I 1000
+ +D+ + +S + D E + +K KT + GS N +
Sbjct: 87 NEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKL 146
Query: 1001 VKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSK 1060
K AKG +K + + + S E KK KE + N+ S + DE + K
Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIKERS--RINSSGESGDESDEFLQSR------K 198
Query: 1061 SAKEHQETKP---VKEEKVKKDYS---KDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK-- 1112
K++Q+ KP ++ D S K V +K KE + KK +E+ L EK
Sbjct: 199 GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258
Query: 1113 ----RKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISL 1168
+K ++++K + FE ++K SK+ V V P+ + K E T D K
Sbjct: 259 LETGKKDQSKQKESQRKFEEETVK-SKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKD 317
Query: 1169 SAPAKKIKLNRETGKKIG-STENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGS 1227
K K +E KK G S + +E KL+ + K+E+ + R + +
Sbjct: 318 KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK 377
Query: 1228 SSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQ-----V 1282
++ +K +E+ + + K + + + A AE + ++Q V
Sbjct: 378 EEERLEQEKRERKK----QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEV 433
Query: 1283 PQ--SKWDKDDFESEEEDVKSTQPISS--VGKPASVIKNVSTKPSNIVKYPEKESEPSEK 1338
P S K +++ K Q + S V + + V + PEKE P
Sbjct: 434 PSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV---PEKEETPPPV 490
Query: 1339 IQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKES--N 1396
+ +D + ++ E K + + KENPE+ + + E+E +
Sbjct: 491 EPEEEEDTEDAGLDDW---EAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 1397 LDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTD--YDT--------R 1446
+ E+G + ++ + SD+ DS + K P+++ +D YD+ R
Sbjct: 548 EEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKK---PSKEMSSDSEYDSDDDRTKEER 604
Query: 1447 EYSSSKRRDEKNELTRRKD 1465
Y +KRR EK L K+
Sbjct: 605 AYDKAKRRIEKRRLEHSKN 623
Score = 78.2 bits (191), Expect = 7e-14
Identities = 151/730 (20%), Positives = 261/730 (35%), Gaps = 148/730 (20%)
Query: 1034 KTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVK----EEKVKKDYSKD-----V 1084
K KS S++ D + + A + QE + K +EK K+D+ +D +
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 1085 KSEKLTTKEEKAKKPNEKNKPLDNKGE----KRKRKTEEKGVDKDFESSSMKISKLEVTE 1140
+ L + KA + KP +N E K K+K +KG + F+ + E E
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDS-----EELE 117
Query: 1141 IVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK 1200
K+ +P E + + D + K K + K GS E+ N+K
Sbjct: 118 DKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSK----- 172
Query: 1201 LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIK 1260
K+K + R +G G S D S G +K + K
Sbjct: 173 -----------KIKERSRINSSGESGDES---DEFLQSRKG--------QKKNQKNKPGP 210
Query: 1261 TMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVST 1320
+E N D+ A + + V Q K +K + E ++ D + +
Sbjct: 211 NIESGNEDDDASFK----IKTVAQKKAEKKERERKKRDEEKAK----------------- 249
Query: 1321 KPSNIVKYPEKES-EPSEKIQKFTKDVSHEIIQHEVKSSKN------SASSEKGKTKDRD 1373
+ K EKE E +K Q K+ + + VKS AS EK +T
Sbjct: 250 ----LRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA 305
Query: 1374 YSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDF 1433
E + +K K + EKE ++ ++G K+ ++ +EA K + R ++
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEK-EKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEE 364
Query: 1434 TPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG 1493
R ++ + +E + EK E ++K+ + + G K + +R+ +
Sbjct: 365 RIKRLEELEAKRKE--EERLEQEKRERKKQKEKERKERLKKEG-KLLTKSQREARARAEA 421
Query: 1494 DSKKSNSS----PSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARN----- 1544
K + PS+D P KRP E K K P + K V E+
Sbjct: 422 TLKLLQAQGVEVPSKDSLPK--------KRPIYEDKKRKKIPQQLESKEVSESMELCAAV 473
Query: 1545 --------NKESSGNKLLYILNPPETQVEKEQITGQI-----DKSTVKPKPQLSHSSRLS 1591
KE + PP + E+E+ T + + + +++
Sbjct: 474 EVMEQGVPEKEET---------PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVH 524
Query: 1592 SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQV 1651
++ +E E + E D ES +EE S D +D+ V K+S T
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTL----- 579
Query: 1652 GISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKK-EKKKHKKHKKH 1710
PS+ SS S +S D + K+++ +K K + K+
Sbjct: 580 -----------DKKPSK-----------EMSSDSEYDSDDDRTKEERAYDKAKRRIEKRR 617
Query: 1711 KKHKKHAGTE 1720
+H K+ TE
Sbjct: 618 LEHSKNVNTE 627
Score = 69.7 bits (169), Expect = 2e-11
Identities = 115/474 (24%), Positives = 183/474 (38%), Gaps = 78/474 (16%)
Query: 861 GSNYPEKLSARDGHNQKDNTKSKEK---ESENAPGDG--------KGNKHKKHRKRRKGE 909
G E L +R G QK N K+K ES N D + KK R+R+K +
Sbjct: 187 GDESDEFLQSRKG--QKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD 244
Query: 910 ESEGFLNP----ELLETSRKSR----------EPTGVEENKTDSLFVLPSRDDATPVRDE 955
E + L E LET +K + E V+ T V+P+ ++ +
Sbjct: 245 EEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKA---ET 301
Query: 956 PMDAESITFKSVSEKDKRERDKPKAKG-----DKTKRKNDGSAVSK--KENIVKPAKGPQ 1008
P AE +E DK+++DK K KG +K K+K A K +E + K + +
Sbjct: 302 PTAAEDD-----NEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE 356
Query: 1009 EKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQET 1068
+ E ER R E K KEE + + K QK+++ +K K +E
Sbjct: 357 RQKREEEERIKRLEELEAKRKEE-ERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREA 415
Query: 1069 KPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPL--DNKGEKRKRKTEEKGVDKDF 1126
+ E +K ++ V E +K K +P+ D K +K ++ E K V +
Sbjct: 416 RARAEATLKLLQAQGV--------EVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESM 467
Query: 1127 E-SSSMKI------SKLEVTEIVKPSPKRKME----PDTEKMDRTPEKDKISLSAPAKKI 1175
E +++++ K E V+P + E D E M E +K+ + ++
Sbjct: 468 ELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEV 527
Query: 1176 KLNRETGKKIGSTENISNTKEPSEKLESTS---------SKVKQEKVKGKVRRKVTGTEG 1226
K N E ++ E E E+ E S KV EK GK K E
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Query: 1227 SSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMI 1280
SS + D + K++ + + +R +E N NT II +
Sbjct: 588 SSDSEYDSDDDRTKEERAYDKAKRRIEKRR-----LEHSKNVNTEKLRAPIICV 636
Score = 67.4 bits (163), Expect = 1e-10
Identities = 85/410 (20%), Positives = 148/410 (36%), Gaps = 68/410 (16%)
Query: 1359 KNSASSEKGKTKDRDYSVLEKE--------NPEKRKNSTQPEKESNLDRLNEQGNFKSLS 1410
K SE D D L E E +K+ + +KE +E K L
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63
Query: 1411 QSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRN 1470
+ S EA+ T A P + + ++ +++ ++ +K +
Sbjct: 64 ELSLEAQGIKADRETVAVK-----PTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118
Query: 1471 KDSASGQKNKPREE-----------RDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR 1519
KDS S + KP+ E LPKK G ++KSN + D+ +K+
Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN-----SKK 173
Query: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVK 1579
E ++ D L++R GQ K
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRK--------------------------GQKKNQKNK 207
Query: 1580 PKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKA 1639
P P + + E D+A+F+ ++ ++ KE E + K + + K
Sbjct: 208 PGPNIESGN--------EDDDASFKI---KTVAQKKAEKKERERKKRDEEKAKLRKL-KE 255
Query: 1640 KESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSAS-SAESQDSKKKKKK 1698
KE L+T Q +Q S+ +G S + + +A D++ KKK
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKK 315
Query: 1699 KEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEK 1748
K+KKK K K+ K+ +K G K+ + K K ++ + K +E+E+
Sbjct: 316 KDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365
Score = 66.6 bits (161), Expect = 2e-10
Identities = 111/599 (18%), Positives = 226/599 (37%), Gaps = 82/599 (13%)
Query: 1179 RETGKKIGSTENISNTKEPSEKLESTSSKVKQE--KVKGKVRRKVTGTEGSSSTLVDYTS 1236
++ K ST++ + + ++E + +QE K KGK +++ + ++
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63
Query: 1237 TSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEE 1296
S + K D + +K E + T+ + QS D D E E+
Sbjct: 64 ELSLEAQGI-----KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118
Query: 1297 EDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVK 1356
+D KS + KP + + S + K P+K ++K K D S E + K
Sbjct: 119 KDSKSKK----TAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNK-KWDGSEEDEDNSKK 173
Query: 1357 SSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEA 1416
+ S + G++ D L+ +K+ +P ++ +FK + + K+A
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233
Query: 1417 RTSDKHDSTRASSNKDFTPNRDK------KTDYDTREYSSSKRRDE--KNELT------- 1461
++ R ++K K D ++ S K +E K+++T
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293
Query: 1462 ---RRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSS--PSRDRKPHDHKATYD 1516
+ ++P+ +D G K K +++ KKG + K+ PS+ +A
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKK---KKGEKEEKEKEKKKGPSKATVKAMQEALAK 350
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS 1576
K E K ++ K E+ LEA+ +E +L + Q EKE+ K
Sbjct: 351 LKEEEERQKREEEERIKRLEE--LEAKRKEEE---RLEQEKRERKKQKEKER------KE 399
Query: 1577 TVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVK----EEESSGNISKDLK 1632
+K + +L S+ + E + E S+ ++ K E++ I + L+
Sbjct: 400 RLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLE 459
Query: 1633 DKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDS 1692
K V ++ E V++ G+ + + P V P + + AS E++
Sbjct: 460 SKEVSESMELCAAVEVMEQGVPEKEE-TPPPVEPEEEEDTEDAGLDDWEAMASDEETE-- 516
Query: 1693 KKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
++E ++ H K+ ++ +++E+E+E+D++
Sbjct: 517 -----------------------------KVEGNKVHIEVKENPEEEEEEEEEEEEDEE 546
Score = 60.5 bits (145), Expect = 1e-08
Identities = 91/461 (19%), Positives = 189/461 (40%), Gaps = 52/461 (11%)
Query: 1286 KWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKD 1345
K K+ E +D +++ + A K + S K EK+ + ++ D
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDE-----DD 57
Query: 1346 VSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGN 1405
+ E+ + +++ A E K + + E + +K+K + +K+S D +E+
Sbjct: 58 ILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE 117
Query: 1406 FKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD 1465
K SK +T+ + S+ D N+ K + S+ K + + K
Sbjct: 118 DKD----SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173
Query: 1466 SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETK 1525
R++ ++SG+ +E +KG ++K+ P+ + D A++ K T
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIK-----TV 228
Query: 1526 SVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQI-TGQIDKSTVKPKPQL 1584
+ K K+RE+ + R+ +++ KL EKE++ TG+ D+S K +
Sbjct: 229 AQKKAEKKERER---KKRDEEKAKLRKLK----------EKEELETGKKDQSKQKESQRK 275
Query: 1585 SHSSRLSSDLTRET------DEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEK 1638
+ S +T +T +E A P E D+E + K+++ K+ K+K +K
Sbjct: 276 FEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG-EKEEKEKEKKK 334
Query: 1639 AKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKK 1698
S T +Q +++ + Q R E ++K+K+++
Sbjct: 335 GP-SKATVKAMQEALAKLKEEEE-------------RQKREEEERIKRLEELEAKRKEEE 380
Query: 1699 K---EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKS 1736
+ EK++ KK K+ ++ ++ L KSQ+ + ++
Sbjct: 381 RLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEA 421
Score = 42.4 bits (98), Expect = 0.004
Identities = 45/191 (23%), Positives = 82/191 (42%), Gaps = 8/191 (4%)
Query: 1575 KSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGN--ISKDLK 1632
KS K K + D+ +E +E + E ++D E+ V+VK E++ SKD K
Sbjct: 39 KSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRET-VAVKPTENNEEEFTSKDKK 97
Query: 1633 DKIVEKAKESLDT--AAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1690
K + K+S D + ++ S+++ + P V + + A+
Sbjct: 98 KKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKS 157
Query: 1691 DSKKKKKKKEKKKHKKHKKHKKHKK--HAGTEV-ELEKSQKHKHKKKKSKKNKDKEKEKE 1747
+ K ++++ KK K+ + +G E E +S+K + K +K+K + E E
Sbjct: 158 NKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNE 217
Query: 1748 KDDQKVKSVTV 1758
DD K TV
Sbjct: 218 DDDASFKIKTV 228
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 85.1 bits (209), Expect = 5e-16
Identities = 192/955 (20%), Positives = 345/955 (36%), Gaps = 171/955 (17%)
Query: 669 SKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR--S 726
S SRS S+RS+S S+S SRS SRS+SR + YRSRSR++ RSR R S
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSR-----------KKRYRSRSRTYSRSRSRDRMYS 52
Query: 727 PPYRRYHSRSRS---PQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVD 783
YRR + +R P +RG+ R QG R + YR V
Sbjct: 53 RDYRRDYRNNRGMRRPYGYRGRG---RGYYQGGGGRYHRGGYRPV--------------- 94
Query: 784 FRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTR 843
W ++ + G S R + S +R +R
Sbjct: 95 -------------------WNRRHSRSPRRGRSRSRSPKRRSVSSQR-----------SR 124
Query: 844 GR-REDYVGGQSHRSRNIGSNYP---EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKH 899
R R Y +S RS + S+ P +S R G +K K++ + E +P K +
Sbjct: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
Query: 900 KKHR----------KRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDA 949
K + K + G + P L R P + + PS+ +
Sbjct: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP-----HSPSPIATPPSQ--S 237
Query: 950 TPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKEN---------- 999
+ D PM + + K+ + + N S S +N
Sbjct: 238 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 297
Query: 1000 ----IVKPAKGPQEK--------VDGERERSPRSEPPIKKAKEETPKT-----DNTKSSS 1042
+ P P+++ DG + + ++ +K+ +E + NT+
Sbjct: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 357
Query: 1043 SSQKDEKITGTPR-KAHSKSAKEHQETKPVKEEKVKKDYSKDVKS-------EKLTTKEE 1094
+S++ G + + A ++ K ++K D + K ++
Sbjct: 358 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
Query: 1095 KAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSP---KRKME 1151
++ + +G K K K KG + K KL+ T V P K K +
Sbjct: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHK 477
Query: 1152 PDTEKMDRTPEKDKISLSAPAKKIKL------NRETGKKIGSTENISNTKEPSEKLESTS 1205
+ + +R K + K KL + K + + E + +E +++ +
Sbjct: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537
Query: 1206 SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTM 1262
S + +VK K+ ++L +ST V+K +E R++ IK
Sbjct: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLP 593
Query: 1263 EEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNV 1318
+ + + + + ++ ++ + ++ K + E K+T+ S+ K + + +
Sbjct: 594 QASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRI 653
Query: 1319 STKPSNIVKYPEKESEP---SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRD 1373
PS + K+ E E+ QK K + + ++H++ + S E+G +K
Sbjct: 654 DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG-- 711
Query: 1374 YSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDF 1433
+E+ RK P+ + +KS SK R D S+ +S++
Sbjct: 712 ----SRESSGSRKQEKTPK---------DYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
Query: 1434 TPNRDKKTDYDTREYSSSKRRDEKN-----ELTRRKDSPSRNKDSASGQKNKPREERDLP 1488
+R++K RE + K ++R + + ++D K R
Sbjct: 759 PSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF 818
Query: 1489 KKGTG--DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLE 1541
++G G + KKS SSP + HD K D +EE + KDR K E
Sbjct: 819 QRGRGRFNFKKSGSSP---KWTHD-KYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
Score = 76.3 bits (186), Expect = 3e-13
Identities = 145/748 (19%), Positives = 293/748 (39%), Gaps = 108/748 (14%)
Query: 1017 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
Query: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1126
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 148 ------YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFN 201
Query: 1127 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIG 1186
+SS+ SP+ P + TP S S +
Sbjct: 202 KSSATSGDIWPGLSAYDNSPR---SPHSPSPIATPPSQSSSCS-----------DAPMLS 247
Query: 1187 STENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVR 1246
+ + NT PS+ S ++ R +G+ G+ S+ + S P R
Sbjct: 248 TVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 296
Query: 1247 KSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDDF 1292
+S KT D R + + TA + +S+ + D
Sbjct: 297 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
Query: 1293 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSHE 1349
E+ +E + + S K S K+ + E +E +E ++F K V +
Sbjct: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLAD 416
Query: 1350 IIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSL 1409
K+ A++ T++ K + + + S +E N +L E G
Sbjct: 417 -------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNY-KLKETGYVVER 468
Query: 1410 SQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRKD 1465
++K+ + +S R + K+ K++ D +YS K D + + T R++
Sbjct: 469 PSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 528
Query: 1466 SPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYD 1516
SP R K AS P ++ + P T D +++ +K + ++ +D
Sbjct: 529 SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 588
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQIDK 1575
+ + +KS ++ + H++ ++ KE LN T +K +
Sbjct: 589 HIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLNERFTSYQK----ATEEH 640
Query: 1576 STVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDK 1634
ST + P++ +S S L + T A E + E + + + ++ + S ++ D+ +
Sbjct: 641 STRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDRR 698
Query: 1635 IVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAESQ 1690
E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 699 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
Query: 1691 DSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
S +++K+ +K++ ++ K H + K+++G
Sbjct: 759 PSSREEKESKKEREEEFKTHHEMKEYSG 786
Score = 63.9 bits (154), Expect = 1e-09
Identities = 153/715 (21%), Positives = 259/715 (36%), Gaps = 123/715 (17%)
Query: 649 KEESKSPYSGSSYSRS----SYTYSKSRSGSTRSRSYSRSFSRSHSRS---YSRSPPYPR 701
+ S+SP G S SRS S + +SRS S RS SRS S SRS YS+SP R
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
Query: 702 RGRGKSRNYRSRS--RSHGYHRSRSRSPPYRRY-HSRSRSPQAFRGQSPNKRNVPQGETE 758
RG + + ++ + +S+S+ P + H S S F S ++ G +
Sbjct: 157 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 216
Query: 759 REYFNRYREVPPPYDMKAYYGRSVDFRDPFE-----KERYREWERKYREWYEKYYKGYAA 813
+ R P P S K + + E+ G
Sbjct: 217 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 276
Query: 814 GAQPR--PSANRE-NFSPERFLPLNI---RNSP--FTRGRREDYVGGQSHRSRNIG---- 861
R PS N + P R P +N+P +RGR Y G + G
Sbjct: 277 NGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
Query: 862 --SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK-------KHRKRRKGEESE 912
++ ++ D N +D SKEK SE +G+ + K ++K +SE
Sbjct: 337 RFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
Query: 913 GFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS-VSEKD 971
G + E E R+ R+ ++ K+ F S + + E + +KS VS K
Sbjct: 397 GD-DTEETEDYRQFRKSVLADQGKS---FATASHRNT--------EEEGLKYKSKVSLKG 444
Query: 972 KRERD------------------KPKAKGDKTKRKNDGS-AVSKKENIVKPAKGPQEK-- 1010
RE D +P DK K ++ S ++ K+ P + EK
Sbjct: 445 NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
Query: 1011 ------------VDGERERSPRSEPPIK-------------KAKEETPKTDNTKSSSSSQ 1045
+D + + R E P++ K K D++ +S
Sbjct: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 564
Query: 1046 KDEKITGTPRKAHSKSAKEHQETK--------PVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
KD + T H S K+ QE + P + + + + + S KE+ K
Sbjct: 565 KDRLLAST--LVH--SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
Query: 1098 KP----NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD 1153
NE+ E+ + + + + + S + K +R + +
Sbjct: 621 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK----HTRLAGEERVFKEE 676
Query: 1154 TEKMDRTPEKDKISL--SAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1211
+K D+ D L ++ + ++E G GS E+ + K+ EK + K
Sbjct: 677 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQ--EKTPKDYKEYKSY 734
Query: 1212 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
K K +R+ + SSS+ S SS ++S+++ + + M+EY+
Sbjct: 735 KDDSKHKREQDHSRSSSSS----ASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
Score = 47.0 bits (110), Expect = 2e-04
Identities = 82/434 (18%), Positives = 168/434 (38%), Gaps = 60/434 (13%)
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
Query: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR----- 1469
+R+S + + S + + KK + + +E S K + ++ + PS
Sbjct: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEF 200
Query: 1470 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1519
NK SA S N PR T S+ S+ S + H K T
Sbjct: 201 NKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
Query: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1571
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
Query: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1630
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
Query: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1685
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
Query: 1686 SAESQDSKKKKKKKEKKKHKKHKKHKKHK----KHAGTEVELEKSQKHKHKKKKSKKNKD 1741
++ K K K K +++ ++ K K G VE + K KHK++ +
Sbjct: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI 486
Query: 1742 KEKEKEKDDQKVKS 1755
K++ + ++VKS
Sbjct: 487 TVKKETQSPEQVKS 500
Score = 31.6 bits (70), Expect = 7.1
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 1665 SPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
S SRSHS S S++RS SSS S + S KK+ + + + + + + + +
Sbjct: 4 SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSR 53
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 84.7 bits (208), Expect = 7e-16
Identities = 188/963 (19%), Positives = 352/963 (36%), Gaps = 191/963 (19%)
Query: 669 SKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR--S 726
S SRS S+RS+S S+S SRS SRS+SR + YRSRSR++ RSR R S
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSR-----------KKRYRSRSRTYSRSRSRDRMYS 52
Query: 727 PPYRRYHSRSRS---PQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVD 783
YRR + +R+ P +RG+ R QG R + YR V
Sbjct: 53 RDYRRDYRNNRAMRRPYGYRGRG---RGYYQGGGGRYHRGGYRPV--------------- 94
Query: 784 FRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTR 843
W ++ + G S R + S +R +R
Sbjct: 95 -------------------WNRRHSRSPRRGRSRSRSPKRRSVSSQR-----------SR 124
Query: 844 GR-REDYVGGQSHRSRNIGSNYP---EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKH 899
R R Y +S RS + S+ P +S R G +K K++ + E +P K +
Sbjct: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
Query: 900 KKHR----------KRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDA 949
K + K + G + P L R P + + PS+ +
Sbjct: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP-----HSPSPIATPPSQ--S 237
Query: 950 TPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKEN---------- 999
+ D PM + + K+ + + N S S +N
Sbjct: 238 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 297
Query: 1000 ----IVKPAKGPQEK--------VDGERERSPRSEPPIKKAKEETPKT-----DNTKSSS 1042
+ P P+++ DG + + ++ +K+ +E + NT+
Sbjct: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 357
Query: 1043 SSQK---------------------DEKITGTPRKAHSKSAKEHQETKPVKE--EKVKKD 1079
+S++ +K +G +K + + +ET+ ++ + V D
Sbjct: 358 ASKEKGSEKGRAEGEWEDQEALDYFSDKESG-KQKFNDSEGDDTEETEDYRQFRKSVLAD 416
Query: 1080 YSKDVKSEKLTTKEEKAKKPNEK-----NKPLDNKGEKRKRKTEEKGVDKDFESSSMKIS 1134
K + EE+ K K N+ D E++ K +E G + S++
Sbjct: 417 QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKH 476
Query: 1135 KLEVTEIVKPSPKRKME-PDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISN 1193
K E + + K++ + P+ K ++ KD S P K + + E +
Sbjct: 477 KEEDKNSERITVKKETQSPEQVKSEKL--KDLFDYSPPLH---------KNLDAREKSTF 525
Query: 1194 TKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTD 1253
+E +++ +S + +VK K+ ++L +ST V+K +E
Sbjct: 526 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE--- 582
Query: 1254 TKRTV---IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV----KSTQPIS 1306
R++ IK + + + + + ++ ++ + ++ K + E K+T+ S
Sbjct: 583 -FRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHS 641
Query: 1307 SVGKPASVIKNVSTKPSNIVKYPEKESEP---SEKIQKFTKDVSHEI--IQHEVKSSKNS 1361
+ K + + + PS + K E E+ QK K + + ++H++ +
Sbjct: 642 TRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE 701
Query: 1362 ASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDK 1421
S E+G +K +E+ RK P+ + +KS SK R D
Sbjct: 702 RSKERGDSKG------SRESRGSRKQEKTPK---------DYKEYKSYKDDSKHKREQDH 746
Query: 1422 HDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKN-----ELTRRKDSPSRNKDSASG 1476
S+ +S++ +R++K RE + K ++R + + ++D
Sbjct: 747 SLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVD 806
Query: 1477 QKNKPREERDLPKKGTG--DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKD 1534
K R ++G G + KKS SSP + + + + E K+ CK+
Sbjct: 807 YWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKE 866
Query: 1535 REK 1537
++
Sbjct: 867 EKE 869
Score = 73.6 bits (179), Expect = 2e-12
Identities = 144/748 (19%), Positives = 294/748 (39%), Gaps = 108/748 (14%)
Query: 1017 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
Query: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1126
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 148 ------YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFN 201
Query: 1127 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIG 1186
+SS+ SP+ P + TP S S +
Sbjct: 202 KSSATSGDIWPGLSAYDNSPR---SPHSPSPIATPPSQSSSCS-----------DAPMLS 247
Query: 1187 STENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVR 1246
+ + NT PS+ S ++ R +G+ G+ S+ + S P R
Sbjct: 248 TVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 296
Query: 1247 KSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDDF 1292
+S KT D R + + TA + +S+ + D
Sbjct: 297 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
Query: 1293 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSHE 1349
E+ +E + + S K S K+ + E +E +E ++F K V +
Sbjct: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLAD 416
Query: 1350 IIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSL 1409
K+ A++ T++ K + + + S +E N D+ E G
Sbjct: 417 -------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN-DKHKETGYVVER 468
Query: 1410 SQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRKD 1465
++K+ + +S R + K+ K++ D +YS K D + + T R++
Sbjct: 469 PSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 528
Query: 1466 SPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYD 1516
SP R K AS P ++ + P T D +++ +K + ++ +D
Sbjct: 529 SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 588
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQIDK 1575
+ + +KS ++ + H++ ++ KE L+ T +K +
Sbjct: 589 HIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLSERFTSYQK----ATEEH 640
Query: 1576 STVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDK 1634
ST + P++ +S S L ++T A E + E + + + ++ + S ++ D+ +
Sbjct: 641 STRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDHR 698
Query: 1635 IVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAESQ 1690
E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 699 RKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSS 758
Query: 1691 DSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
S +++K+ +K++ ++ K H + K+++G
Sbjct: 759 PSSREEKESKKEREEEFKTHHEMKEYSG 786
Score = 60.8 bits (146), Expect = 1e-08
Identities = 152/715 (21%), Positives = 260/715 (36%), Gaps = 123/715 (17%)
Query: 649 KEESKSPYSGSSYSRS----SYTYSKSRSGSTRSRSYSRSFSRSHSRS---YSRSPPYPR 701
+ S+SP G S SRS S + +SRS S RS SRS S SRS YS+SP R
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
Query: 702 RGRGKSRNYRSRS--RSHGYHRSRSRSPPYRRY-HSRSRSPQAFRGQSPNKRNVPQGETE 758
RG + + ++ + +S+S+ P + H S S F S ++ G +
Sbjct: 157 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 216
Query: 759 REYFNRYREVPPPYDMKAYYGRSVDFRDPFE-----KERYREWERKYREWYEKYYKGYAA 813
+ R P P S K + + E+ G
Sbjct: 217 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 276
Query: 814 GAQPR--PSANRE-NFSPERFLPLNI---RNSP--FTRGRREDYVGGQSHRSRNIG---- 861
R PS N + P R P +N+P +RGR Y G + G
Sbjct: 277 NGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
Query: 862 --SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK-------KHRKRRKGEESE 912
++ ++ D N +D SKEK SE +G+ + K ++K +SE
Sbjct: 337 RFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
Query: 913 GFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS-VSEKD 971
G + E E R+ R+ ++ K+ F S + + E + +KS VS K
Sbjct: 397 GD-DTEETEDYRQFRKSVLADQGKS---FATASHRNT--------EEEGLKYKSKVSLKG 444
Query: 972 KRERD------------------KPKAKGDKTKRKNDGS-AVSKKENIVKPAKGPQEK-- 1010
RE D +P DK K ++ S ++ K+ P + EK
Sbjct: 445 NRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
Query: 1011 ------------VDGERERSPRSEPPIK-------------KAKEETPKTDNTKSSSSSQ 1045
+D + + R E P++ K K D++ +S
Sbjct: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 564
Query: 1046 KDEKITGTPRKAHSKSAKEHQETK--------PVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
KD + T H S K+ QE + P + + + + + S KE+ K
Sbjct: 565 KDRLLAST--LVH--SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
Query: 1098 KP----NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD 1153
+E+ E+ + + + + + S + K + +R + +
Sbjct: 621 SAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK----DTRLAGEERVFKEE 676
Query: 1154 TEKMDRTPEKDKISL--SAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1211
+K D+ D L ++ + ++E G GS E+ + K+ EK + K
Sbjct: 677 NQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQ--EKTPKDYKEYKSY 734
Query: 1212 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
K K +R+ + SSS+ S SS ++S+++ + + M+EY+
Sbjct: 735 KDDSKHKREQDHSLSSSSS----ASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
Score = 48.9 bits (115), Expect = 4e-05
Identities = 84/435 (19%), Positives = 171/435 (39%), Gaps = 62/435 (14%)
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
Query: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR----- 1469
+R+S + + S + + KK + + +E S K + ++ + PS
Sbjct: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEF 200
Query: 1470 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1519
NK SA S N PR T S+ S+ S + H K T
Sbjct: 201 NKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
Query: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1571
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
Query: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1630
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
Query: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1685
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
Query: 1686 SAESQDSKKKKKKKEKKKHK-----KHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1740
++ K K K K ++ + +K+ KHK+ G VE + K KHK++ +
Sbjct: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKE-TGYVVERPSTTKDKHKEEDKNSER 485
Query: 1741 DKEKEKEKDDQKVKS 1755
K++ + ++VKS
Sbjct: 486 ITVKKETQSPEQVKS 500
Score = 31.6 bits (70), Expect = 7.1
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 1665 SPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
S SRSHS S S++RS SSS S + S KK+ + + + + + + + +
Sbjct: 4 SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSR 53
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 84.3 bits (207), Expect = 9e-16
Identities = 192/940 (20%), Positives = 333/940 (35%), Gaps = 149/940 (15%)
Query: 909 EESEGFLNPELLETSRKSREPTGVEENKTDSLF-VLPSRDDATPVRDEPMDAESITFKSV 967
E+SE + E S PT V + SL +L ++ ++P + P A + +
Sbjct: 543 EDSES--SSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 968 SEKDKRERDKPKAKGDKTKRKNDGSAVS-----------------KKENIVKPAKGPQEK 1010
+EK + + D + +A++ KK N AK +
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 1011 VDGERER------SPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKI-------------T 1051
V + R SP P + P D++ S S ++EK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 1052 GTPRKAHSKSAKEH--QETKPVKEEKVKKDYS--KDVKSEKLTTKEEKAKKPNEKNKPLD 1107
G KA S K Q T PV K + K K E + EE++ P
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 1108 NKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKIS 1167
K +K + + S+ IS K++ + R P+ +
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 1168 LSAPAKKIKLNR--------ETGKK--IGSTENISNTKEPSEKLESTSSKVKQEKVKGKV 1217
PA + + +TG + GS+E S+++E +E L K +++ +
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 1218 R-RKVTGTEGSSSTLVDYTSTSST-------GGSPVRKSEEKTD-----TKRTVIKTMEE 1264
K + +G++ T T S+ GS +S+ + T VIK
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 1265 YNNDNTAPAEDVIIMIQVP-----------QSKWDKDDFESEEEDV-KSTQPISS----- 1307
+ + N +PA Q +S ESE+EDV +TQ ++
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1308 ----------VGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKS 1357
+ AS+ S+K S+ + +K+ P+ ++ + Q
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ 1080
Query: 1358 SKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEAR 1417
+K + K K + + E+ + ++S+ S D QG + + +R
Sbjct: 1081 AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSR 1140
Query: 1418 TSDKHDSTRASSNKD--FTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRN----- 1470
T + T A S++D P++ + Y T + + + K + SPS +
Sbjct: 1141 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK-ATPKLDSSPSVSSTLAA 1199
Query: 1471 KDSASG-QKNKPREERDL--PKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSV 1527
KD G Q+ KP++ + PK G G S ++P + RKP P T ++
Sbjct: 1200 KDDPDGKQEAKPQQAAGMLSPKTG-GKEAASGTTPQKSRKPKKGAGN-----PQASTLAL 1253
Query: 1528 DKN----------PCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKST 1577
N P + + + E + +++ + K + + S
Sbjct: 1254 QSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG 1313
Query: 1578 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVE 1637
+P + S + E EA+ P+ + S+ K +++SG D+K+K
Sbjct: 1314 DQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKA--KRDKASG----DVKEK--- 1364
Query: 1638 KAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1697
K K SL G + + G Q+ + SKK+KK
Sbjct: 1365 KGKGSL--------GSQGAKDEPEEELQKGMGTVEGGDQS-----------NPKSKKEKK 1405
Query: 1698 KKEKKKHKKHKKHKKHK-KHAGTEVELEKSQKHKHKKKKS 1736
K +K+K K KK KK K K A T+ SQK K KKKK+
Sbjct: 1406 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1445
Score = 61.6 bits (148), Expect = 6e-09
Identities = 124/602 (20%), Positives = 218/602 (36%), Gaps = 102/602 (16%)
Query: 1147 KRKMEPDTE-KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTS 1205
KRK E D + +T D IS S +++ E + T + + +L ST+
Sbjct: 62 KRKAEEDAALQAKKTRVSDPISTSESSEE------------EEEAEAETAKATPRLASTN 109
Query: 1206 SKVKQEKVKGKVRRKV---TGTEGSSSTLVDYTSTSST------GGSPVRKSEEKTDTKR 1256
S V + ++ K T G + + + +T T G SP + +E +T
Sbjct: 110 SSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT-- 167
Query: 1257 TVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEED--------VKSTQPISS- 1307
T++ EE + A M+ Q+ +D S ++ VK Q +S
Sbjct: 168 TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS 227
Query: 1308 -----------------VGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKD----- 1345
VG +K + P+ K PE+ESE SE+ + ++
Sbjct: 228 VSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGT 287
Query: 1346 -----VSHEIIQHEVKSSKNSASSEKGKT---KDRDYSVLEKENPEKRKNSTQPEKESNL 1397
S +I+Q S+ + KG T + +V + K + ++ E +
Sbjct: 288 RSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESS 347
Query: 1398 DRLNEQGNFKSLSQSSKEARTSDKHDST---RASSNKDFTPNRDKKTDYDTREYSSSKRR 1454
D E K+L Q+ +TS ++ + S K P KT + + KR
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 1455 DEKNELTRRKDSPSRNKDSASGQKNKPR-EERDLPKKGTGDSKKSNSSPSRDRKPHDHKA 1513
++ + DS A P+ P K +S + ++P+ RK A
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAA 464
Query: 1514 TYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQI 1573
+ E+++S + DRE L A N ++ + P+ + G +
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDRE--ALAAMN-----AAQVKPLGKSPQVKPASTMGMGPL 517
Query: 1574 DKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1633
K P + S+ + + E DSES+ EESS + ++
Sbjct: 518 GKGAGPVPPGKVGPATPSAQVGKW-----------EEDSESS----SEESSDSSDGEVPT 562
Query: 1634 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSH---SSSASSAESQ 1690
+ ++SL I + + SSP+ P + P Q ++ +S SS ES
Sbjct: 563 AVAPAQEKSLG-------NILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 615
Query: 1691 DS 1692
DS
Sbjct: 616 DS 617
Score = 53.5 bits (127), Expect = 2e-06
Identities = 64/273 (23%), Positives = 107/273 (39%), Gaps = 34/273 (12%)
Query: 868 LSARDGHNQKDNTKSKEKESENAPGDG-----KGNKHKKHRKRRKGEESEGFLNPELLET 922
L+A+D + K K ++ +P G G +K RK +KG NP+
Sbjct: 1197 LAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAG-----NPQA--- 1248
Query: 923 SRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKG 982
++ N T L P P+ + + A + K ++E ++ER K
Sbjct: 1249 -----STLALQSNITQCLLGQP-----WPLNEAQVQASVV--KVLTELLEQERKKVVDTT 1296
Query: 983 DKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSS 1042
++ RK S K A+ P+ K + E + K T +S
Sbjct: 1297 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTST-------TSK 1349
Query: 1043 SSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEK 1102
K +K +G ++ K + Q K EE+++K ++ K +K KK ++K
Sbjct: 1350 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1409
Query: 1103 NKPLDNKGEKRKRKTEEKGVDKDFESSSMKISK 1135
K +K +K K+K +K KD ES S K K
Sbjct: 1410 RK--KDKEKKEKKKKAKKASTKDSESPSQKKKK 1440
Score = 50.1 bits (118), Expect = 2e-05
Identities = 157/868 (18%), Positives = 305/868 (35%), Gaps = 129/868 (14%)
Query: 921 ETSRKSREPTGVEE--NKTDSLFVLPSRDDAT-PVRDEPMDAESITFKSVSEKDKRERD- 976
++ RKS EP+ ++T+ +P+ A P A+S + + S D+ + +
Sbjct: 155 KSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214
Query: 977 KPKAKGDKTKRKNDGSAVSKKENIV-KPAKGPQEKVDGERERSPRSEPPIKKAKEETPKT 1035
KP K + K S+VS KE+ K A P + D + + PP K+AK+ ++
Sbjct: 215 KPSVKPAQVK----ASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEES 270
Query: 1036 DNTKSSSSSQKDEKI-TGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEE 1094
++++ S S+++ T + KA K + + P K K +
Sbjct: 271 ESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 1095 KAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDT 1154
KA KP E ++ + + +T ++S + K SP++ P
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP-- 388
Query: 1155 EKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSE--------KLESTSS 1206
P K + A AK RE + S E+ S + P++ ++ + S+
Sbjct: 389 ----APPGK---TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441
Query: 1207 KVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
K+ KG T G ++ V R S E++D+ R + M
Sbjct: 442 PAKESPRKGAAPAPPRKT-GPAAAQVQVGKQEEDS----RSSSEESDSDREALAAMN--- 493
Query: 1267 NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIV 1326
A V + + PQ K ST + +GK A + P+
Sbjct: 494 ------AAQVKPLGKSPQVK------------PASTMGMGPLGKGAGPVPPGKVGPAT-- 533
Query: 1327 KYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK 1386
PS ++ K+ +D S+S E + D + EK
Sbjct: 534 --------PSAQVGKWEED-------------SESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 1387 NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTR 1446
+ K ++ ++ K + D +S+ SS D +
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS--------DSADSEEAP 624
Query: 1447 EYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDR 1506
++ + ++ + K P + +AS + R P+K + + SSP+
Sbjct: 625 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA--- 681
Query: 1507 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEK 1566
T+RP E++ S +++ ++ + + +S G L + +
Sbjct: 682 ------VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-------QVKAAS 728
Query: 1567 EQITGQIDKSTV-----KPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEE 1621
+ G + + T K P ++ + + ++E + + S ++ SVK+
Sbjct: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 1622 ESSGNISK----------DLKDKIVEKAKESLDTAAVVQVGISRNQSHSS---------P 1662
++ N + K+V A ++ + RN +S+ P
Sbjct: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
Query: 1663 SVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVE 1722
SV + + + + +QT S SS E DS+++ + + K K H+ A
Sbjct: 849 SVGKAVA-TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK----PSGKTHQIRAALAPA 903
Query: 1723 LEKSQKHKHKKKKSKKNKDKEKEKEKDD 1750
E +K K + ++DD
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDD 931
Score = 48.9 bits (115), Expect = 4e-05
Identities = 53/260 (20%), Positives = 101/260 (38%), Gaps = 24/260 (9%)
Query: 1473 SASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDH----KATYDTKRPNEETKSVD 1528
S G+K K E+ L K T S ++S S + + KAT N D
Sbjct: 57 SELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGAD 116
Query: 1529 KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS 1588
P +EK A+ E +G + +P + ++G+ + + +P
Sbjct: 117 L-PSSMKEK----AKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSA------ 165
Query: 1589 RLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV 1648
++ L ET+E P + + VS + +SS + D+ + K S+ A V
Sbjct: 166 --NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV 223
Query: 1649 VQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK 1708
+S +S P+R +P+ + + +K+ KK +E+ + +
Sbjct: 224 KASSVSTKES-------PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG 276
Query: 1709 KHKKHKKHAGTEVELEKSQK 1728
+ + AGT +++ S+K
Sbjct: 277 SESEEEAPAGTRSQVKASEK 296
Score = 43.9 bits (102), Expect = 0.001
Identities = 133/721 (18%), Positives = 258/721 (35%), Gaps = 88/721 (12%)
Query: 1007 PQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQ 1066
P+E + E S SE AK + K+S +PRK + +
Sbjct: 335 PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKT 394
Query: 1067 ETKPVKEEKVKKDYSKDVKSEKLTTKEE--KAKKPNEKNKPLDNKGEKRKRKTEEKGVDK 1124
K + K++ SE+ ++EE KP+ K + K +
Sbjct: 395 GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 1125 DFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK 1184
+ ++++V K E D+ + D+ +L+A +N K
Sbjct: 455 PPRKTGPAAAQVQV---------GKQEEDSRSSSEESDSDREALAA------MNAAQVKP 499
Query: 1185 IGSTENISNTKEPSEKLESTSSKVKQEKVKGKV----------RRKVTGTEGSSSTLVDY 1234
+G K P K ST K G V +V E S + +
Sbjct: 500 LG--------KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
Query: 1235 TSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFES 1294
+S SS G P + + + +++ + P + + +QV K D+ ES
Sbjct: 552 SSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK-PMDNSES 610
Query: 1295 EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHE 1354
EE S+ S PA++ KP+ +K P+ ++ P + + V+ + +
Sbjct: 611 SEE---SSDSADSEEAPAAMTA-AQAKPA--LKIPQTKACPKKTNTTASAKVAPVRVGTQ 664
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
+A+S G + +V +S+ E +S ++ K
Sbjct: 665 APRKAGTATSPAGSSP----AVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRD-----EKNELTRRKDSPSR 1469
+ + S + P KT + + K+ D E+++ SP++
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 1470 NKDSA--SGQKNKPREERDLPKKG---------TGDSKKSNSSPSRDRKP--HDHKATYD 1516
K S + K P R KG T ++ SPS+ + P + +T
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKS 1576
+ P SV K + +E SG+ + E+ E+E T +
Sbjct: 841 ARGP-ASVPSVGKAVATAAQAQT----GPEEDSGS------SEEESDSEEEAET----LA 885
Query: 1577 TVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIV 1636
VKP + +H R + +E+ P S +++ SG+ S++
Sbjct: 886 QVKPSGK-THQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-- 942
Query: 1637 EKAKESLDTAAVVQ---VGISRNQSHSSPSVSPSRSH---SPSGSQTRSHSSSASSAESQ 1690
+A ++ +A V++ + + N+S + P+ +P+++ +P ++ ++ +SS+ES+
Sbjct: 943 GEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
Query: 1691 D 1691
D
Sbjct: 1003 D 1003
Score = 40.8 bits (94), Expect = 0.012
Identities = 112/626 (17%), Positives = 215/626 (34%), Gaps = 64/626 (10%)
Query: 921 ETSRKSREPTGVEENKTDSLFVLPS------RDDATPVRDEPMDAESITFKSVSEKDKRE 974
E S S E + EE V PS R P ++ P + T + +
Sbjct: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 925
Query: 975 RDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPK 1034
K G ++ + + K P VD R + + P + TP+
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1035 ----TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSK-DVKSEKL 1089
+++T SSSS+ +++ + + + + T P ++ S S K
Sbjct: 986 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 1045
Query: 1090 TTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK 1149
+++ KK +D+ G S + ++ KP
Sbjct: 1046 SSRISDGKKQEGPATQVDSA----------VGTLPATSPQSTSVQAKGTNKLRKPKL--- 1092
Query: 1150 MEPDTEKMDRTPEK--DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKL-ESTSS 1206
P+ ++ + PE D S + + + E + S + T +E L E T++
Sbjct: 1093 --PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAA 1150
Query: 1207 KVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSST-GGSPVRKSEEKTDTKRTVIKTM--- 1262
+ ++ V S S L Y + T S K+ K D+ +V T+
Sbjct: 1151 ESSEDDVVAP----------SQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAK 1200
Query: 1263 EEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKP-ASVIKNVSTK 1321
++ + A + M+ K + S KS +P G P AS + S
Sbjct: 1201 DDPDGKQEAKPQQAAGMLS---PKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1257
Query: 1322 PSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKEN 1381
++ P +E ++Q V E+++ E K ++ K + L +
Sbjct: 1258 TQCLLGQPWPLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1315
Query: 1382 PEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1441
P R ++ +K+ G S S ++ T+ K + R ++ D + K +
Sbjct: 1316 PAARTPRSKKKKKLGA------GEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGS 1369
Query: 1442 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDS---KKS 1498
S +DE E ++ D ++ + K +++ D KK KK+
Sbjct: 1370 ------LGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1423
Query: 1499 NSSPSRDRKPHDHKATYDTKRPNEET 1524
+ ++D + K K+ E+T
Sbjct: 1424 KKASTKDSESPSQKKKKKKKKTAEQT 1449
Score = 39.7 bits (91), Expect = 0.026
Identities = 89/383 (23%), Positives = 145/383 (37%), Gaps = 55/383 (14%)
Query: 926 SREPTGVEENKTDSLFV--LPSRDDATPVRDEPMDAE-SITFKSVSEKDKRERDKPKAK- 981
S + T V+ T+ L LP AT + D+E S S SE+D K+
Sbjct: 1073 SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAH 1132
Query: 982 --GDKTKRKN----DGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKT 1035
G R + +A S ++++V P+ Q + G +P P +A + TPK
Sbjct: 1133 TLGPTPSRTETLVEETAAESSEDDVVAPS---QSLLSGYM--TPGLTPANSQASKATPKL 1187
Query: 1036 DNTKSSSSS-----QKDEKITGTPRKAHSK-----SAKEHQE-TKPVKEEKVKKDYSKDV 1084
D++ S SS+ D K P++A KE T P K K KK
Sbjct: 1188 DSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQ 1247
Query: 1085 KSEKLTTKE------------EKAKKPNEKNKPLDNKGEKRKRK---TEEKGVDKDFESS 1129
S +A+ K L E+ ++K T ++ K +ES
Sbjct: 1248 ASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESR 1307
Query: 1130 SMKISKLEVTEIVKPSPKRKMEPDTE--KMDRTPEKDKISLSAPAKKIKLNRETGKKIG- 1186
K+S + S K+K E + +PEK + AK+ K + + +K G
Sbjct: 1308 KRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGK 1367
Query: 1187 -STENISNTKEPSEKLES----------TSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYT 1235
S + EP E+L+ ++ K K+EK K R+K + +
Sbjct: 1368 GSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKAS 1427
Query: 1236 STSSTGGSPVRKSEEKTDTKRTV 1258
+ S S +K ++K ++TV
Sbjct: 1428 TKDSESPSQKKKKKKKKTAEQTV 1450
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 83.6 bits (205), Expect = 2e-15
Identities = 186/948 (19%), Positives = 332/948 (35%), Gaps = 161/948 (16%)
Query: 669 SKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR--S 726
S SRS S+RS+S S+S SRS SRS+SR + YRSRSR++ RSR R S
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSR-----------KKRYRSRSRTYSRSRSRDRMYS 52
Query: 727 PPYRRYHSRSRS---PQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVD 783
YRR + +R+ P +RG+ R QG R + YR V
Sbjct: 53 RDYRRDYRNNRAMRRPYGYRGRG---RGYYQGGGGRYHRGGYRPV--------------- 94
Query: 784 FRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTR 843
W ++ + G S R + S +R +R
Sbjct: 95 -------------------WNRRHSRSPRRGRSRSRSPKRRSVSSQR-----------SR 124
Query: 844 GR-REDYVGGQSHRSRNIGSNYP---EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKH 899
R R Y +S RS + S+ P +S R G +K K++ + E +P K +
Sbjct: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEE 184
Query: 900 KKHRKRRKGEES---------------EGFLNPELLETSRKSREPTGVEENKTDSLFVLP 944
K ES G + S S P +++ S P
Sbjct: 185 PKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAP 244
Query: 945 SRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPA 1004
++ P S S+ +R G + S + + PA
Sbjct: 245 MLSTVHSAKNTP----SQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 1005 KGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKD-----EKITGTPRKAHS 1059
K + E RS +ET KT + ++ ++ ++A
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 1060 KSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNE------------------ 1101
+ E + E++ DY D +S K + + E
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 1102 ----KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSP---KRKMEPDT 1154
++ + +G K K K KG + K K + T V P K K + +
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
Query: 1155 EKMDRTPEKDKISLSAPAKKIKL------NRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
+ +R K + K KL + K + + E + +E +++ +S
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTMEEY 1265
+ +VK K+ ++L +ST V+K +E R++ IK +
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLPQAS 596
Query: 1266 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNVSTK 1321
+ + + + ++ ++ + ++ K + E K+T+ S+ K + + +
Sbjct: 597 KSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDIS 656
Query: 1322 PSNIVKYPEKESEP---SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRDYSV 1376
PS + K E E+ QK K + + ++H++ + S E+G +K
Sbjct: 657 PSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKG----- 711
Query: 1377 LEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPN 1436
+E+ RK P+ + +KS SK R D S+ +S++ +
Sbjct: 712 -SRESRGSRKQEKTPK---------DYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSS 761
Query: 1437 RDKKTDYDTREYSSSKRRDEKN-----ELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1491
R++K RE + K ++R + + ++D K R ++G
Sbjct: 762 REEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRG 821
Query: 1492 TG--DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREK 1537
G + KKS SSP + + + + E K+ CK+ ++
Sbjct: 822 RGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
Score = 72.8 bits (177), Expect = 3e-12
Identities = 144/748 (19%), Positives = 294/748 (39%), Gaps = 108/748 (14%)
Query: 1017 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
Query: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1126
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 148 ------YSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFN 201
Query: 1127 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIG 1186
+SS+ SP+ P + TP S S +
Sbjct: 202 KSSATCGDIWPGLSAYDXSPR---SPHSPSPIATPPSQSSSCS-----------DAPMLS 247
Query: 1187 STENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVR 1246
+ + NT PS+ S ++ R +G+ G+ S+ + S P R
Sbjct: 248 TVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 296
Query: 1247 KSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDDF 1292
+S KT D R + + TA + +S+ + D
Sbjct: 297 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
Query: 1293 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSHE 1349
E+ +E + + S K S K+ + E +E +E ++F K V +
Sbjct: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLAD 416
Query: 1350 IIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSL 1409
K+ A++ T++ K + + + S +E N D+ E G
Sbjct: 417 -------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN-DKHKETGYVVER 468
Query: 1410 SQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRKD 1465
++K+ + +S R + K+ K++ D +YS K D + + T R++
Sbjct: 469 PSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 528
Query: 1466 SPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYD 1516
SP R K AS P ++ + P T D +++ +K + ++ +D
Sbjct: 529 SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 588
Query: 1517 TKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQIDK 1575
+ + +KS ++ + H++ ++ KE L+ T +K +
Sbjct: 589 HIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLSERFTSYQK----ATEEH 640
Query: 1576 STVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDK 1634
ST + P++ +S S L ++T A E + E + + + ++ + S ++ D+ +
Sbjct: 641 STRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDHR 698
Query: 1635 IVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAESQ 1690
E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 699 RKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSS 758
Query: 1691 DSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
S +++K+ +K++ ++ K H + K+++G
Sbjct: 759 PSSREEKESKKEREEEFKTHHEMKEYSG 786
Score = 60.5 bits (145), Expect = 1e-08
Identities = 152/715 (21%), Positives = 260/715 (36%), Gaps = 123/715 (17%)
Query: 649 KEESKSPYSGSSYSRS----SYTYSKSRSGSTRSRSYSRSFSRSHSRS---YSRSPPYPR 701
+ S+SP G S SRS S + +SRS S RS SRS S SRS YS+SP R
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
Query: 702 RGRGKSRNYRSRS--RSHGYHRSRSRSPPYRRY-HSRSRSPQAFRGQSPNKRNVPQGETE 758
RG + + ++ + +S+S+ P + H S S F S ++ G +
Sbjct: 157 RGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSA 216
Query: 759 REYFNRYREVPPPYDMKAYYGRSVDFRDPFE-----KERYREWERKYREWYEKYYKGYAA 813
+ R P P S K + + E+ G
Sbjct: 217 YDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 276
Query: 814 GAQPR--PSANRE-NFSPERFLPLNI---RNSP--FTRGRREDYVGGQSHRSRNIG---- 861
R PS N + P R P +N+P +RGR Y G + G
Sbjct: 277 NGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
Query: 862 --SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK-------KHRKRRKGEESE 912
++ ++ D N +D SKEK SE +G+ + K ++K +SE
Sbjct: 337 RFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
Query: 913 GFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS-VSEKD 971
G + E E R+ R+ ++ K+ F S + + E + +KS VS K
Sbjct: 397 GD-DTEETEDYRQFRKSVLADQGKS---FATASHRNT--------EEEGLKYKSKVSLKG 444
Query: 972 KRERD------------------KPKAKGDKTKRKNDGS-AVSKKENIVKPAKGPQEK-- 1010
RE D +P DK K ++ S ++ K+ P + EK
Sbjct: 445 NRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
Query: 1011 ------------VDGERERSPRSEPPIK-------------KAKEETPKTDNTKSSSSSQ 1045
+D + + R E P++ K K D++ +S
Sbjct: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 564
Query: 1046 KDEKITGTPRKAHSKSAKEHQETK--------PVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
KD + T H S K+ QE + P + + + + + S KE+ K
Sbjct: 565 KDRLLAST--LVH--SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
Query: 1098 KP----NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD 1153
+E+ E+ + + + + + S + K + +R + +
Sbjct: 621 SAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK----DTRLAGEERVFKEE 676
Query: 1154 TEKMDRTPEKDKISL--SAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1211
+K D+ D L ++ + ++E G GS E+ + K+ EK + K
Sbjct: 677 NQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQ--EKTPKDYKEYKSY 734
Query: 1212 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
K K +R+ + SSS+ S SS ++S+++ + + M+EY+
Sbjct: 735 KDDSKHKREQDHSLSSSSS----ASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
Score = 45.1 bits (105), Expect = 6e-04
Identities = 85/435 (19%), Positives = 171/435 (39%), Gaps = 62/435 (14%)
Query: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
Query: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYS--SSKRRDEKNELTRRKDSPSR--- 1469
+R+S + + S + + KK + + +E S SK ++E + S S
Sbjct: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEF 200
Query: 1470 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1519
NK SA S PR T S+ S+ S + H K T
Sbjct: 201 NKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
Query: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1571
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
Query: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1630
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
Query: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1685
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
Query: 1686 SAESQDSKKKKKKKEKKKHK-----KHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1740
++ K K K K ++ + +K+ KHK+ G VE + K KHK++ +
Sbjct: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKE-TGYVVERPSTTKDKHKEEDKNSER 485
Query: 1741 DKEKEKEKDDQKVKS 1755
K++ + ++VKS
Sbjct: 486 ITVKKETQSPEQVKS 500
Score = 31.6 bits (70), Expect = 7.1
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 1665 SPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
S SRSHS S S++RS SSS S + S KK+ + + + + + + + +
Sbjct: 4 SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSR 53
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 82.4 bits (202), Expect = 4e-15
Identities = 157/771 (20%), Positives = 297/771 (38%), Gaps = 119/771 (15%)
Query: 1054 PRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKR 1113
P K +K KE + VKE KVK++ ++K K+ +EE+ P E+ KP++++ E++
Sbjct: 409 PEKVVNKQCKECEN---VKEIKVKEENETEIKEIKM--EEERNIIPREE-KPIEDEIERK 462
Query: 1114 KRKTEEKGVDKDF-ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPA 1172
+ G K+ ES + + I KP ++ + R E I + A
Sbjct: 463 ENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEE 522
Query: 1173 KKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLV 1232
+K K + K ++ P K ++K+K K+ ++ E S
Sbjct: 523 EKAKSGYDEWIKADKIVRPADKNVPKIK--------HRKKIKNKLDKEKDKDEKYSPKNC 574
Query: 1233 DYTSTSS----TGGSPVRKSE-EKTDTKRTVIKTMEEYNNDNTAPAEDVIIM-----IQV 1282
S T SP S+ + TD K N +TA + + I +Q
Sbjct: 575 KLRRLSKPPFQTNPSPEMVSKLDLTDAK-----------NSDTAHIKSIEITSILNGLQA 623
Query: 1283 PQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKF 1342
+S + +SE+ED + Q + + GK S I +++ ++++ KE + S + +
Sbjct: 624 SESSAE----DSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLI---SKEEQNSSSLLEE 676
Query: 1343 TKDVSHEIIQHEV-KSSKNSASSEKGKTKDRDYSVLE--KENPEKRKNSTQPEKESNLDR 1399
K + +I V KS + + ++D DY E K+ + +K++T + + R
Sbjct: 677 NKVHADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKR 736
Query: 1400 -----LNEQGNFKSLSQSSKEARTSDK-----HDSTRASSNKDFTPNRDKKTDYDTREYS 1449
N + K+ S KE + +K +S+ +SS++D + K T T++Y+
Sbjct: 737 GKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSSDEDEEETKAKMT--PTKKYN 794
Query: 1450 SSKRRDEK----------NELTRRKDSPSRNKDSASGQKNKPREERDL--------PKKG 1491
+ + + +E+ ++ N D Q ++ ++ +D+ PKK
Sbjct: 795 GLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDERL-QNSRAKDRKDVWSSIQGQWPKKT 853
Query: 1492 TGDSKKSNSSPSRDRKPH------------DHKATYDTKRPNEETK-----SVDKNPCKD 1534
+ + + + PH A ++ P+ E + +VD P ++
Sbjct: 854 LKELFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEE 913
Query: 1535 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQIT---GQIDKSTV------KPKPQLS 1585
+ V + + SSG+ + + PP T +T G +S+V P +
Sbjct: 914 KTVEVNDRKAEFPSSGSNSV-LNTPPTTPESPSSVTVTEGSRQQSSVTVSEPLAPNQEEV 972
Query: 1586 HSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDT 1645
S + +D T E D A E +S+ S+ + + S + S + + EKA
Sbjct: 973 RSIKSETDSTIEVDSVAGELQDLQSEGNSSPAGFDASVSSSSSNQPEPEHPEKACTGQKR 1032
Query: 1646 AAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHK 1705
Q G S ++ + ++ G T S S SA +K + K K
Sbjct: 1033 VKDAQGGGSSSKKQKRSHKATVVNNKKKGKGTNSSDSEELSAGESITKSQPVKSVSTGMK 1092
Query: 1706 KHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
H KS K KN DK+ + ++ ++ V
Sbjct: 1093 SHS---------------TKSPARTQSPGKCGKNGDKDPDLKEPSNRLPKV 1128
Score = 72.0 bits (175), Expect = 5e-12
Identities = 155/810 (19%), Positives = 309/810 (38%), Gaps = 103/810 (12%)
Query: 885 KESENAPGDGKGNKHKKHRKRRKGEESEGFLNPEL------LETSRKSREPTGVEENKTD 938
KE EN +++ K K EE + E +E + G ++N +
Sbjct: 418 KECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIERKENIKPSLGSKKNLLE 477
Query: 939 SLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKE 998
S+ ++ ++ +P D E++ K E K + ++ K K+ K +
Sbjct: 478 SIPTHSDQEKEVNIK-KPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGYDEWIKAD 536
Query: 999 NIVKPA----------KGPQEKVDGERER----SPR-------SEPPIK--KAKEETPKT 1035
IV+PA K + K+D E+++ SP+ S+PP + + E K
Sbjct: 537 KIVRPADKNVPKIKHRKKIKNKLDKEKDKDEKYSPKNCKLRRLSKPPFQTNPSPEMVSKL 596
Query: 1036 DNTKSSSSSQKDEK-------ITGTPRKAHSKSAKEHQETKPVKE------EKVKKDYSK 1082
D T + +S K + G S E ++ + ++ E+ K D+
Sbjct: 597 DLTDAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLT 656
Query: 1083 DVKSEKLTTKEEKAKKPNEKN---------KPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1133
+ +++ ++ +E+ + E+N KP+ E+ ++ E D D+E +
Sbjct: 657 NNRNDLISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTK 716
Query: 1134 SKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISN 1193
+ +V K + + +P ++ R + L + K + K+ EN SN
Sbjct: 717 KRKDVK---KDTTDKSSKPQIKRGKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSN 773
Query: 1194 TKEPSEKLESTSSKVKQEKVKG-KVRRKVTGTEG--SSSTLVDYTSTSSTGGSPVRKSEE 1250
+ ++ E+ + +K G + +RK T G S + V S R
Sbjct: 774 SSSDEDEEETKAKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDERLQNS 833
Query: 1251 KTDTKRTV---------IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKS 1301
+ ++ V KT++E +D+ A P+ ++ ++ E+ +S
Sbjct: 834 RAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAA-ASPPHPAPEEGVAEESLQTVAEE-ES 891
Query: 1302 TQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQ--HEVKSSK 1359
P + KP V NV +KP EK E +++ +F S+ ++ S
Sbjct: 892 CSPSVELEKPPPV--NVDSKP-----IEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPESP 944
Query: 1360 NSASSEKGKTKDRDYSVLEKENPEKRK-NSTQPEKESNLDRLNEQGNFKSLSQSSKEART 1418
+S + +G + +V E P + + S + E +S ++ + G + L +
Sbjct: 945 SSVTVTEGSRQQSSVTVSEPLAPNQEEVRSIKSETDSTIEVDSVAGELQDLQSEGNSSPA 1004
Query: 1419 SDKHDSTRASSNKDFTPNRDK-----KTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1473
+ +SSN+ + +K K D + SS ++ +++ K + NK
Sbjct: 1005 GFDASVSSSSSNQPEPEHPEKACTGQKRVKDAQGGGSSSKKQKRS----HKATVVNNKKK 1060
Query: 1474 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1533
G + EE + T + S S K H K+ T+ P + K+ DK+P
Sbjct: 1061 GKGTNSSDSEELSAGESIT--KSQPVKSVSTGMKSHSTKSPARTQSPGKCGKNGDKDP-- 1116
Query: 1534 DREKHVLEARNNKESSGNKLLYILNPPETQVEKEQIT------GQIDKSTVKPKPQLSHS 1587
L+ +N+ K + ++ E E+IT +I K + K +++
Sbjct: 1117 -----DLKEPSNRLPKVYKWSFQMSDLENMTSAERITILQEKLQEIRKHYLSLKSEVASI 1171
Query: 1588 SRLSSDLTRETDEAAFEPDYNESDSESNVS 1617
R L ++ E+A + S S S+++
Sbjct: 1172 DRRRKRLKKKERESAATSSSSSSPSSSSIT 1201
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 82.0 bits (201), Expect = 5e-15
Identities = 167/898 (18%), Positives = 330/898 (36%), Gaps = 153/898 (17%)
Query: 920 LETSRKSREPTGVEENKTDSLFVLPSRDDATPVRD-EPMDAESITFKSVSEKDKRERDKP 978
++T +E + ++ S+ VL + + +P + E+ S KD +
Sbjct: 497 MKTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTAL 556
Query: 979 KAKGDKTKRKNDGSAVSKKEN-------IVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1031
+ T + + S +KK+ + K K + +D + +R + K+ E
Sbjct: 557 SSTESCTMKGEEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLE 616
Query: 1032 TPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTT 1091
+ K + +++ +S I + A K E Q T V + VKK + +K + T
Sbjct: 617 SEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTVGGQSVKKVDLETLKEDSEFT 676
Query: 1092 KEEKAKKPNEKN----KPLDNKGEKRKRKTEEKGVDKDFESSS-------------MKIS 1134
K E N + +P + KG +K K + K V ++ ++S +K++
Sbjct: 677 KVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLT 736
Query: 1135 KLEVTEIVKP-SPKRKMEPDT--EKMDRTPEKDKIS--------LSAPAKKI------KL 1177
+ KP SP + +EP+ EK ++ EK + +S P K+ K
Sbjct: 737 IRISSRKKKPDSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKA 796
Query: 1178 NRETGKKIGSTENISNTKEPSEKLE-------STSSKVKQEKVKGKVRRKVTGTEGSSST 1230
+++ G+ E S + ++K E T+SKV + K KGKVR + T G
Sbjct: 797 DKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSRTRGRWK- 855
Query: 1231 LVDYTSTSSTGGSPVRKS------EEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQ 1284
Y+S + GS KS EE+ +++ ++ +E P +I++
Sbjct: 856 ---YSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEPCKKCGLPNHPELILLC--- 909
Query: 1285 SKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTK 1344
+ S + + P +I P+ E F
Sbjct: 910 ------------DSCDSGYHTACLRPPLMII-------------PDGEW--------FCP 936
Query: 1345 DVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK-----------NSTQPEK 1393
H+++ +++ + +D D ++ +KE E+RK N P++
Sbjct: 937 PCQHKLLCEKLEE----------QLQDLDVALKKKERAERRKERLVYVGISIENIIPPQE 986
Query: 1394 ESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKR 1453
+ E+ S+++ R S + + +F D+ + D +E
Sbjct: 987 PDFSEDQEEKKKDSKKSKANLLERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGG-- 1044
Query: 1454 RDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKA 1513
R KD ++ ++ ++ + + ++K+ + + RK
Sbjct: 1045 ------------GVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLN 1092
Query: 1514 TYDTKRPNEETKSVDKNPCKD--REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITG 1571
D+ +E +S D+ D +++ V+ N ES + PP
Sbjct: 1093 DLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEED-------PPSND------DS 1139
Query: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDL 1631
D + + + S R S L R+T + + D E +SE N +S + S D
Sbjct: 1140 DTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEEN----SRDSESDFSDDF 1195
Query: 1632 KDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQD 1691
D VE + Q+ N S S +S R H SS+ES++
Sbjct: 1196 SDDFVETRRRRSRRNQKRQI----NYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEE 1251
Query: 1692 SKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
S K ++ + K+ K+ + + + E ++ + + K S+K + + E++
Sbjct: 1252 SYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIETDEEE 1309
Score = 79.3 bits (194), Expect = 3e-14
Identities = 155/762 (20%), Positives = 285/762 (37%), Gaps = 118/762 (15%)
Query: 1030 EETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKS--- 1086
+ + + DN+ S S +DE+ T ++ + +E +E++ +K E+ D +
Sbjct: 215 KNSSQQDNSSRESPSLEDEE---TKKEEETPKQEEQKESEKMKSEEQPMDLENRSTANVL 271
Query: 1087 EKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSP 1146
E+ T K+EK + P+ K EK + EEK + K+ ES S K E VKP
Sbjct: 272 EETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKE-ESDSFK-------ENVKP-- 321
Query: 1147 KRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSS 1206
++ + ++ P+ K S+ P + E G NI ++ E +EK S
Sbjct: 322 ---IKVEVKECRADPKDTKSSMEKPVAQEPERIEFGG------NIKSSHEITEK-----S 367
Query: 1207 KVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
+ EK+K + K+ P++K E K +
Sbjct: 368 TEETEKLKNDQQAKI----------------------PLKKREIKL-------------S 392
Query: 1267 NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPAS-----------VI 1315
+D +P + + P ++ KD+ + EEE K I+++G V
Sbjct: 393 DDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVA 452
Query: 1316 KNVSTKPSNIVKYPEKESE--PSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKG----KT 1369
N T+P Y KE PS+ T+ E + + S K ++ K
Sbjct: 453 PNFKTEPIETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSMKTGELEKETAPLRKD 512
Query: 1370 KDRDYSVLEKENPEKR-KNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRAS 1428
D SVLE + + + + PE E++LD + S + S + K +
Sbjct: 513 ADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSPK 572
Query: 1429 SNKDFTP---------NRDKKT--DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQ 1477
+ KD P + KKT D D + S K+ L K +++
Sbjct: 573 TKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPS 632
Query: 1478 KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREK 1537
E+ +K + + +++ + K K +T + + E V+ + + +
Sbjct: 633 NIIDHCEKLASEKEVVECQSTSTVGGQSVK----KVDLETLKEDSEFTKVEMDNLDNAQT 688
Query: 1538 HVLEARNNKESS--GNKLLYILNPPE--TQVEKEQITGQIDKSTVKPKPQLSHSSRLSSD 1593
+E + + S +K Y L P E T E +IT + K +K ++S +
Sbjct: 689 SGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKP-- 746
Query: 1594 LTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI 1653
++ EP+ + +E KEEE + N+ + L+ + S TA V ++
Sbjct: 747 ---DSPPKVLEPENKQEKTE-----KEEEKT-NVGRTLR----RSPRISRPTAKVAEIRD 793
Query: 1654 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK-KKKEKKKHKKHKKHKK 1712
+ S + +T S + +SK K K K K + + +
Sbjct: 794 QKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSRTRGR 853
Query: 1713 HKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754
K + E E S+K ++ ++ + +E DD+ K
Sbjct: 854 WKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEPCK 895
Score = 77.0 bits (188), Expect = 1e-13
Identities = 163/779 (20%), Positives = 283/779 (36%), Gaps = 155/779 (19%)
Query: 1012 DGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPV 1071
D SP E K +EETPK + K S + +E+ E++ T V
Sbjct: 221 DNSSRESPSLEDEETKKEEETPKQEEQKESEKMKSEEQ----------PMDLENRSTANV 270
Query: 1072 KEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSM 1131
EE T K+EK + P+ K EK + EEK + K+ ES S
Sbjct: 271 LEE--------------TTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKE-ESDSF 315
Query: 1132 KISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENI 1191
K E VKP ++ + ++ P+ K S+ P + ++I NI
Sbjct: 316 K-------ENVKP-----IKVEVKECRADPKDTKSSMEKPV------AQEPERIEFGGNI 357
Query: 1192 SNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK 1251
++ E +EK S + EK+K + K+ P++K E K
Sbjct: 358 KSSHEITEK-----STEETEKLKNDQQAKI----------------------PLKKREIK 390
Query: 1252 TDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKP 1311
++D +P + + P ++ KD+ + EEE K I+++G
Sbjct: 391 -------------LSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHE 437
Query: 1312 AS-----------VIKNVSTKPSNIVKYPEKES--EPSEKIQKFTKDVSHEIIQHEVKSS 1358
V N T+P Y KE PS+ T+ E + + S
Sbjct: 438 GKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSM 497
Query: 1359 KNSASSEK----GKTKDRDYSVLEKENPEKR-KNSTQPEKESNLDRLNEQGNFKSLSQSS 1413
K ++ K D SVLE + + + + PE E++LD + S + S
Sbjct: 498 KTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALS 557
Query: 1414 KEARTSDKHDSTRASSNKDFTP---------NRDKKT--DYDTREYSSSKRRDEKNELTR 1462
+ K + + KD P + KKT D D + S K+ L
Sbjct: 558 STESCTMKGEEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLES 617
Query: 1463 RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNE 1522
K +++ E+ +K + + +++ + K K +T + +
Sbjct: 618 EKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTVGGQSVK----KVDLETLKEDS 673
Query: 1523 ETKSVDKNPCKDREKHVLEARNNKESS--GNKLLYILNPPE--TQVEKEQITGQIDKSTV 1578
E V+ + + + +E + + S +K Y L P E T E +IT + K +
Sbjct: 674 EFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGI 733
Query: 1579 KPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEK 1638
K ++S S ++ EP+ + +E KEEE + N+ + L+
Sbjct: 734 KLTIRIS-----SRKKKPDSPPKVLEPENKQEKTE-----KEEEKT-NVGRTLR----RS 778
Query: 1639 AKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKK 1698
+ S TA V ++ R+Q ++ G +++ + D K+ KK
Sbjct: 779 PRISRPTAKVAEI---RDQ----------KADKKRGEGEDEVEEESTALQKTDKKEILKK 825
Query: 1699 KEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHK-------KKKSKKNKDKEKEKEKDD 1750
EK + K K K K T K+ +KS ++E+EKE ++
Sbjct: 826 SEKDTNSKVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEE 884
Score = 66.6 bits (161), Expect = 2e-10
Identities = 161/838 (19%), Positives = 292/838 (34%), Gaps = 137/838 (16%)
Query: 868 LSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNP---ELLETSR 924
LS+ + K KS + + + P + + + K+ ++ L+P E+ +++
Sbjct: 556 LSSTESCTMKGEEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTL 615
Query: 925 KSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984
+S +P E +T + + E ++ +S + K + + K +
Sbjct: 616 ESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTVGGQSVKKVDLETLKEDSEF 675
Query: 985 TKRKNDGSAVSKKENIVKPA--KGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSS 1042
TK + D ++ I +P+ KG +K + + P +EET ++NT+ +S
Sbjct: 676 TKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVP---------EEETTASENTEITS 726
Query: 1043 SSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEK 1102
QK+ G S K+ ++ P E K K K E+ T ++
Sbjct: 727 ERQKE----GIKLTIRISSRKKKPDSPPKVLEPENKQ-EKTEKEEEKTNVGRTLRRSPRI 781
Query: 1103 NKPLDNKGEKRKRKTEEK---GVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDR 1159
++P E R +K ++K G D + E S + K + EI+K K E DT
Sbjct: 782 SRPTAKVAEIRDQKADKKRGEGED-EVEEESTALQKTDKKEILK-----KSEKDTNS--- 832
Query: 1160 TPEKDKISLSAPAKKIKLNRETGKKI-GSTENISNTKEPSEKLESTSSKVKQEKVKGKVR 1218
K+S P K+ R TG + G + SN + E +S+ ++E+ K
Sbjct: 833 -----KVSKVKPKGKV---RWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEK---- 880
Query: 1219 RKVTGTEGSSSTLVDYTSTSSTGGSP---------------------------------- 1244
E + L D G P
Sbjct: 881 ------ESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWF 934
Query: 1245 ---------VRKSEEKTDTKRTVIKTME--EYNNDNTAPAEDVIIMIQVPQSKWDKDDFE 1293
K EE+ +K E E + I I PQ +D E
Sbjct: 935 CPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQE 994
Query: 1294 SEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQH 1353
+++D K ++ A++++ ST+ + Y + E E I + +D E
Sbjct: 995 EKKKDSKKSK--------ANLLERRSTRTRKCISY--RFDEFDEAIDEAIEDDIKEADGG 1044
Query: 1354 EVKSSKNSASSEKGKTKDRDYSVLEKENPE-------------KRKNSTQPEKESNLDRL 1400
V K+ ++ + KD ++L++E E KR+ + +SNLD
Sbjct: 1045 GVGRGKDISTITGHRGKDIS-TILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEE 1103
Query: 1401 NEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNEL 1460
+ FK S E SD++ S +D N D TD+ +R R +
Sbjct: 1104 ESEDEFKISDGSQDEFVVSDENPD---ESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSR 1160
Query: 1461 TRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRP 1520
R+ +P + ++ RD + D R R + K + K
Sbjct: 1161 RLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKED 1220
Query: 1521 NEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQ------------ 1568
+E S K+ + +E + R S + N + ++ KE
Sbjct: 1221 SESDGS-QKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTD 1279
Query: 1569 --ITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS 1624
++ + KP R+ +D D A + + DS+ V E+ES+
Sbjct: 1280 EYSEADEEEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQEST 1337
Score = 57.4 bits (137), Expect = 1e-07
Identities = 149/789 (18%), Positives = 290/789 (36%), Gaps = 96/789 (12%)
Query: 876 QKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEEN 935
+ DN + + P + KG+ K K + L PE T+ ++ E T +
Sbjct: 679 EMDNLDNAQTSGIEEPSETKGSMQKSKFKYK--------LVPEEETTASENTEITSERQK 730
Query: 936 KTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDG-SAV 994
+ L + S P D+ + ++++K E+++ K +T R++ S
Sbjct: 731 EGIKLTIRISSRKKKP------DSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRP 784
Query: 995 SKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE----TPKTDNTKSSSSSQKDE-K 1049
+ K ++ K +++ +GE E S K K+E + K N+K S K + +
Sbjct: 785 TAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVR 844
Query: 1050 ITGTPRKAHSK-SAKEHQETKPVKEEKVKKDYSKDVKSEK--LTTKEEKAKKPNEKNKPL 1106
TG+ + K S+ + E ++ + ++ +SE+ L +E KK N P
Sbjct: 845 WTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEPCKKCGLPNHP- 903
Query: 1107 DNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1166
E + D S + L ++ P + P K+ ++++
Sbjct: 904 ------------ELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQL 951
Query: 1167 SLSAPAKKIKLNRETGKK----IG-STENISNTKEPSEKLESTSSKVKQEKVKGKV-RRK 1220
A K K E K+ +G S ENI +EP + K +K K + R+
Sbjct: 952 QDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKKSKANLLERR 1011
Query: 1221 VTGTEGSSSTLVDYTSTS-----------STGGSPVRKSEEKTDTK---RTVIKTMEEYN 1266
T T S D + + GG R + T T + + ++E
Sbjct: 1012 STRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEER 1071
Query: 1267 NDNTAPAEDVIIMIQVPQSKWDKD-DFESEEEDVKSTQPISSVGKPASVIKNVSTK---- 1321
+N P + + D D D +EE+ + IS + V+ + +
Sbjct: 1072 KENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEE 1131
Query: 1322 --PSN-----------IVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1368
PSN + ++P + S ++++ T + E +S +NS SE
Sbjct: 1132 DPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDF 1191
Query: 1369 TKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRAS 1428
+ D +E R+N +++ N +E + + KE R K + +
Sbjct: 1192 SDDFSDDFVETRRRRSRRNQ---KRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSE 1248
Query: 1429 SNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLP 1488
S + + + + S ++R + D ++ +K R E D
Sbjct: 1249 SEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIETD-E 1307
Query: 1489 KKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES 1548
++ ++ + P+RD +P P+E+ + + E+ E N
Sbjct: 1308 EESCDNAHGDANQPARDSQPR--------VLPSEQESTKKPYRIESDEEEDFE---NVGK 1356
Query: 1549 SGNKLLY-ILNPPETQVEK-----EQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAA 1602
G+ L Y +++ P T + E + G+ + + PK + S+ L+S+ T EA
Sbjct: 1357 VGSPLDYSLVDLPSTNGQSPGKAIENLIGKPTEKSQTPKDNSTASASLASNGTSGGQEAG 1416
Query: 1603 FEPDYNESD 1611
P+ E +
Sbjct: 1417 -APEEEEDE 1424
Score = 48.5 bits (114), Expect = 6e-05
Identities = 84/404 (20%), Positives = 145/404 (35%), Gaps = 50/404 (12%)
Query: 868 LSARDGHNQKD-NTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKS 926
+S GH KD +T E+ EN +K R+R +S+ L+ E E K
Sbjct: 1052 ISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKI 1111
Query: 927 REPTGVE-----ENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAK 981
+ + E EN +S PS DD+ D S + + R+ + + K
Sbjct: 1112 SDGSQDEFVVSDENPDESEEDPPSNDDSDT------DFCSRRLRRHPSRPMRQSRRLRRK 1165
Query: 982 GDKTKRKNDGSAVSKKENIVKPAKG-----PQEKVDGERERSPRSEPPIKKAKEETPKTD 1036
K K +D +EN + V+ R RS R++ KE++
Sbjct: 1166 TPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDG 1225
Query: 1037 NTKSSSSSQKDEKI-------TGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKL 1089
+ KS ++ ++ + + SK++++ + K K K+ S D SE
Sbjct: 1226 SQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEAD 1285
Query: 1090 TTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK 1149
+EE+ KP+ K E+ ++ S ++ E KP +
Sbjct: 1286 EEEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKP---YR 1342
Query: 1150 MEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVK 1209
+E D E+ + E K+GS + S PS +S +
Sbjct: 1343 IESDEEE---------------------DFENVGKVGSPLDYSLVDLPSTNGQSPGKAI- 1380
Query: 1210 QEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTD 1253
E + GK K + +S+ S ++GG EE+ D
Sbjct: 1381 -ENLIGKPTEKSQTPKDNSTASASLASNGTSGGQEAGAPEEEED 1423
Score = 37.4 bits (85), Expect = 0.13
Identities = 49/219 (22%), Positives = 86/219 (39%), Gaps = 18/219 (8%)
Query: 1540 LEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETD 1599
+E +++++ S K + + N E + QID +K Q +SSR S L E
Sbjct: 177 IEEQDDQDGSSWKCI-VRNRNELAETLALLKAQIDPVLLKNSSQQDNSSRESPSLEDEET 235
Query: 1600 EAAFEPDYNESDSESNVSVKEEE----SSGNISKDLKDKIVEKAKESLDTAAVVQVGISR 1655
+ E E ES EE+ + + + L++ V+K KE D +V++
Sbjct: 236 KKEEETPKQEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKE--DEKELVKL---- 289
Query: 1656 NQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
P + P + + + S + K + KE + K K K
Sbjct: 290 ------PVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVKECRADPKDTKSSMEKP 343
Query: 1716 HAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754
A +E K + ++K+ + E EK K+DQ+ K
Sbjct: 344 VAQEPERIEFGGNIKSSHEITEKSTE-ETEKLKNDQQAK 381
Score = 34.3 bits (77), Expect = 1.1
Identities = 33/126 (26%), Positives = 48/126 (38%), Gaps = 24/126 (19%)
Query: 643 REQRRLKEES-KSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPR 701
R+ RRL+ ++ K YS S S+ S S S +S F + R R
Sbjct: 1157 RQSRRLRRKTPKKKYSDDDEEEESEENSRD-SESDFSDDFSDDFVETRRRR-------SR 1208
Query: 702 RGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREY 761
R + + NY+ S S G +S R RR H KR + E+E Y
Sbjct: 1209 RNQKRQINYKEDSESDGSQKSLRRGKEIRRVH---------------KRRLSSSESEESY 1253
Query: 762 FNRYRE 767
++ E
Sbjct: 1254 LSKNSE 1259
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 82.0 bits (201), Expect = 5e-15
Identities = 93/384 (24%), Positives = 154/384 (40%), Gaps = 67/384 (17%)
Query: 1382 PEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1441
PE + E E + R+ E +F S + + +++++ S + + +R
Sbjct: 264 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTR--SKSRSSSK 321
Query: 1442 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSS 1501
+ R+ S SK R + +R + R S +++K RE R K + S
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR----------KSRSRS 371
Query: 1502 PSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPE 1561
SRD++ K T + + E K D+ ++REK E KE NK +
Sbjct: 372 HSRDKR----KDTREKIKEKERVKEKDREKEREREK---EREKEKERGKNK--------D 416
Query: 1562 TQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEE 1621
E+E+ D+ K K D RE ++ + E + E + KE+
Sbjct: 417 RDKEREK-----DREKDKEK-----------DREREREKEHEKDRDKEKEKEQD---KEK 457
Query: 1622 ESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHS 1681
E + SK++ +K + K SR S + SRS S + RS S
Sbjct: 458 EREKDRSKEIDEKRKKDKK-------------SRTPPRSYNASRRSRSSSRERRRRRSRS 504
Query: 1682 SSASSAESQDSKKKKKKKE--KKKHKKHKKHKKHKKHAGTEVELE------KSQKHKHKK 1733
SS S S+ K+K + + ++KK KK +K + H E E KS + K
Sbjct: 505 SSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGK 564
Query: 1734 KKSKKNKDKEKEKEKDDQKVKSVT 1757
+K +KN KEKE + + SV+
Sbjct: 565 EKLEKNSTSLKEKEHNKEPDSSVS 588
Score = 76.6 bits (187), Expect = 2e-13
Identities = 94/395 (23%), Positives = 159/395 (40%), Gaps = 43/395 (10%)
Query: 624 HSNTI---PTTQAPPLSREEFYREQRRLKEESK------SPYSGSSYSRS-----SYTYS 669
HSN P P + +E +R++E P SG S R S+T S
Sbjct: 255 HSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRS 314
Query: 670 KSRSG----STRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR 725
KSRS S R RS S+ SRSH+RS SR R R KS ++ RS+S +SRSR
Sbjct: 315 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKD---RRRSKS-PHKKRSKSRERRKSRSR 370
Query: 726 SPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFR 785
S HSR + R + K V + + E+E RE + + G++ D
Sbjct: 371 S------HSRDKRKDT-REKIKEKERVKEKDREKE-----REREKEREKEKERGKNKDRD 418
Query: 786 DPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGR 845
EK+R ++ E+ EK ++ + + + +R ++ + + R
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
Query: 846 REDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKR 905
S RSR+ S + +R +K+ +++S +P NK K R++
Sbjct: 479 TPPRSYNASRRSRS-SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537
Query: 906 RKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFK 965
+ SE + S + G E+ + +S + + P +S K
Sbjct: 538 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP--------DSSVSK 589
Query: 966 SVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENI 1000
V +KD ++ K + + + N+ + +K E +
Sbjct: 590 EVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV 624
Score = 70.5 bits (171), Expect = 1e-11
Identities = 85/446 (19%), Positives = 161/446 (36%), Gaps = 83/446 (18%)
Query: 1317 NVSTKPSNIVKYPEKESEPSEKIQKFTKD----VSHEIIQHEVKSSKNSASSEKGKTKDR 1372
N KP + P+ ++ E++ K ++ +S I KS++ + T+ +
Sbjct: 258 NAIVKPPEMT--PQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 315
Query: 1373 DYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKD 1432
S + + KR S + N R ++ +S S K +++ ++ S S ++D
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 375
Query: 1433 FTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGT 1492
+ K T +E K +D + E R K+ R K+ G KNK R+ K+
Sbjct: 376 ----KRKDTREKIKEKERVKEKDREKEREREKE---REKEKERG-KNKDRD-----KERE 422
Query: 1493 GDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNK 1552
D +K + +H+ D ++ E+ K ++ KDR K + E R + S
Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE--KDRSKEIDEKRKKDKKS--- 477
Query: 1553 LLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDS 1612
+ P+ ++SR S +RE +
Sbjct: 478 --------------------------RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRT 511
Query: 1613 ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSP 1672
+ K S S++ KDK EK ++ +
Sbjct: 512 SKTIKRKSSRSPSPRSRNKKDKKREKERDHI----------------------------- 542
Query: 1673 SGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHK 1732
S+ R S S +S + + K+K E K+ K K+H K + V E K +
Sbjct: 543 --SERRERERSTSMRKSSNDRDGKEKLE--KNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598
Query: 1733 KKKSKKNKDKEKEKEKDDQKVKSVTV 1758
+++K + + +++ K+ V
Sbjct: 599 TEENKIQHNGNCQLNEENLSTKTEAV 624
Score = 70.1 bits (170), Expect = 2e-11
Identities = 71/337 (21%), Positives = 136/337 (40%), Gaps = 20/337 (5%)
Query: 867 KLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKS 926
K + R G + +T+SK + S + K ++ KHR R + ++ K
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQ-SKHRSRSHNRSRSRQKDRRRSKSPHKK 357
Query: 927 REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK 986
R + E K+ S SRD R++ + E + K + +RER+K + K +
Sbjct: 358 RSKSR-ERRKSRSRS--HSRDKRKDTREKIKEKERV--KEKDREKEREREKEREKEKERG 412
Query: 987 RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK 1046
+ D +K+ K + + + E E+ E ++ KE+ + D +K +K
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 1047 DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPL 1106
+K + TP ++++ S + ++ + + + S+ + K ++ P +NK
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK- 531
Query: 1107 DNKGEKRKRKTEEKGVDKDFESSSMKIS-------KLEVTEIVKPSPKRKMEPDTEKMDR 1159
D K EK + E+ +++ +S K S KLE + EPD+
Sbjct: 532 DKKREKERDHISERR-ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 1160 TPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKE 1196
+KD AP + + G + EN+S E
Sbjct: 591 VDDKD-----APRTEENKIQHNGNCQLNEENLSTKTE 622
Score = 64.3 bits (155), Expect = 1e-09
Identities = 79/330 (23%), Positives = 129/330 (39%), Gaps = 47/330 (14%)
Query: 1001 VKPAKGPQEKVDGERERS-----PRSEPPIKKAKEETPKTDNTKS---SSSSQKDEKITG 1052
++P G + G R RS RS ++ + ++S S S QKD + +
Sbjct: 293 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 352
Query: 1053 TPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK 1112
+P K SKS + + +KD + +K EK KE+ +K E+ K + + E+
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK-EKERVKEKDREKEREREKEREKEKER 411
Query: 1113 RKRKTEEKGVDKDFESSSMKISKLE-VTEIVKPSPKRK-MEPDTEK---------MDRTP 1161
K K +K +KD E K + E E K K K E D EK +D
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471
Query: 1162 EKDKISLSAP-----------AKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQ 1210
+KDK S + P + + + R + S K S + S S+ K+
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK 531
Query: 1211 EKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNT 1270
+K + K R + S STS S R +EK + T +K E ++
Sbjct: 532 DKKREKERDHI------SERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Query: 1271 APAEDVIIMIQVPQSKWDKDDFESEEEDVK 1300
+ +++V DKD +EE ++
Sbjct: 586 SVSKEVD----------DKDAPRTEENKIQ 605
Score = 56.2 bits (134), Expect = 3e-07
Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 6/143 (4%)
Query: 1614 SNVSVKEEESSGNISKDLKDKIVEKAKE--SLDTAAVVQVGISRNQSHSSPSVSPSRSHS 1671
+N VK E + + ++++++ +E S +AA+ N+ S S +RS S
Sbjct: 257 NNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKS 316
Query: 1672 PSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKH 1731
S S++ S + S S + + ++K + + HKK K E +S+ H
Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK--SRERRKSRSRSHSR 374
Query: 1732 KKKKSKKNKDKEKE--KEKDDQK 1752
K+K + K KEKE KEKD +K
Sbjct: 375 DKRKDTREKIKEKERVKEKDREK 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.124 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,473,037
Number of Sequences: 37866
Number of extensions: 4941831
Number of successful extensions: 82598
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1005
Number of HSP's successfully gapped in prelim test: 2320
Number of HSP's that attempted gapping in prelim test: 25922
Number of HSP's gapped (non-prelim): 30074
length of query: 1758
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1642
effective length of database: 13,855,062
effective search space: 22750011804
effective search space used: 22750011804
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.