Guide to the Human Genome
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Search of human proteins with 33383237

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33383237 minichromosome maintenance complex component 10
isoform 1 [Homo sapiens]
         (875 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33383237 minichromosome maintenance complex component 10 isof...  1739   0.0  
gi|33383235 minichromosome maintenance complex component 10 isof...  1733   0.0  
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    47   1e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     46   1e-04
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]      44   7e-04
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]        44   7e-04
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]      44   7e-04
gi|217330641 IWS1 homolog [Homo sapiens]                               44   7e-04
gi|16445033 ACRC protein [Homo sapiens]                                44   7e-04
gi|21735548 centrosomal protein 2 [Homo sapiens]                       44   9e-04
gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]            44   9e-04
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]      43   0.001
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    43   0.001
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    43   0.001
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    43   0.001
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    43   0.001
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    43   0.001
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    43   0.001
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    43   0.001
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]      42   0.002
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]      42   0.002
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform...    42   0.002
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform...    42   0.002
gi|209862789 microtubule associated monoxygenase, calponin and L...    42   0.002
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    42   0.003
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             41   0.004
gi|164419758 bromodomain containing 2 [Homo sapiens]                   40   0.007
gi|4826806 bromodomain containing 2 [Homo sapiens]                     40   0.007
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             40   0.007
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           40   0.007

>gi|33383237 minichromosome maintenance complex component 10 isoform
           1 [Homo sapiens]
          Length = 875

 Score = 1739 bits (4505), Expect = 0.0
 Identities = 875/875 (100%), Positives = 875/875 (100%)

Query: 1   MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60
           MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
Sbjct: 1   MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60

Query: 61  DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120
           DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
Sbjct: 61  DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120

Query: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV 180
           NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV
Sbjct: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV 180

Query: 181 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE 240
           PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
Sbjct: 181 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE 240

Query: 241 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI 300
           TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
Sbjct: 241 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI 300

Query: 301 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK 360
           LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
Sbjct: 301 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK 360

Query: 361 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY 420
           PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
Sbjct: 361 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY 420

Query: 421 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK 480
           KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
Sbjct: 421 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK 480

Query: 481 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA 540
           KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
Sbjct: 481 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA 540

Query: 541 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS 600
           TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
Sbjct: 541 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS 600

Query: 601 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL 660
           RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
Sbjct: 601 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL 660

Query: 661 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR 720
           AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
Sbjct: 661 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR 720

Query: 721 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV 780
           EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
Sbjct: 721 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV 780

Query: 781 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK 840
           VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
Sbjct: 781 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK 840

Query: 841 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 875
           WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
Sbjct: 841 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 875


>gi|33383235 minichromosome maintenance complex component 10 isoform
           2 [Homo sapiens]
          Length = 874

 Score = 1733 bits (4489), Expect = 0.0
 Identities = 874/875 (99%), Positives = 874/875 (99%), Gaps = 1/875 (0%)

Query: 1   MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60
           MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
Sbjct: 1   MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60

Query: 61  DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120
           DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
Sbjct: 61  DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120

Query: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV 180
           NLQEQMKALQEQLKVTTIKQTASPARLQKSP EKSPRPPLKERRVQRIQESTCFSAELDV
Sbjct: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSP-EKSPRPPLKERRVQRIQESTCFSAELDV 179

Query: 181 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE 240
           PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
Sbjct: 180 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE 239

Query: 241 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI 300
           TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
Sbjct: 240 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI 299

Query: 301 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK 360
           LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
Sbjct: 300 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK 359

Query: 361 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY 420
           PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
Sbjct: 360 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY 419

Query: 421 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK 480
           KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
Sbjct: 420 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK 479

Query: 481 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA 540
           KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
Sbjct: 480 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA 539

Query: 541 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS 600
           TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
Sbjct: 540 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS 599

Query: 601 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL 660
           RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
Sbjct: 600 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL 659

Query: 661 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR 720
           AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
Sbjct: 660 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR 719

Query: 721 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV 780
           EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
Sbjct: 720 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV 779

Query: 781 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK 840
           VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
Sbjct: 780 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK 839

Query: 841 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 875
           WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
Sbjct: 840 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 874


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 35/229 (15%)

Query: 545 IMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPP 604
           I+    P IKS+ A+   K        +     E+     + S S + SP+  SS   PP
Sbjct: 245 ILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDS----VLSHSSLSSPSSTSSPEGPP 300

Query: 605 AQPPRTGSEFPRLEGAPAT-MTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAI 663
           A P +  S  P     P   +T K  +G  E             + KL    + ++L   
Sbjct: 301 APPKQHSSTSPFPTSTPLRRITKKFVKGSTE-------------KNKLRLQRDQERLGKQ 347

Query: 664 TKLRAKGQVLTKTNPNSIK-----KKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKK 718
            KLRA+ +   K    + +     KK+K+ +  L+ KER EK      + +DE E A K+
Sbjct: 348 LKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK------REKDEKEKAEKQ 401

Query: 719 RREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQME 767
           R   L     +E Q+ L+AK +     ++ E E + R  E  +K E+ E
Sbjct: 402 R---LKEERRKERQEALEAKLEEK---RKKEEEKRLREEEKRIKAEKAE 444



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 51/191 (26%), Positives = 84/191 (43%), Gaps = 28/191 (14%)

Query: 615 PRLEGAPAT-----MTPK--LGRGVLEGDDVLFYD-----------ESPPPRPK----LS 652
           P+++  PAT     MTP+  +     E D VL +            E PP  PK     S
Sbjct: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTS 310

Query: 653 ALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDEL 712
               +  L  ITK   KG   T+ N   +++ Q+     L+++   E+      +A+   
Sbjct: 311 PFPTSTPLRRITKKFVKGS--TEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAK 368

Query: 713 EPARKKRREQLAYLES---EEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEK 769
           E A+KK+ E+    E    E+ +K  K K++   + +E   E QE     L +K + EE+
Sbjct: 369 EEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428

Query: 770 MRNIREVKCRV 780
            R +RE + R+
Sbjct: 429 KR-LREEEKRI 438


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 7/134 (5%)

Query: 80  DMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIK 139
           + E +  EE+   +Q TE          +E   EE +EE    +E+ +  +E+ K    +
Sbjct: 451 EKETVIVEEQTEETQVTEE---VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE 507

Query: 140 QTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPD 199
           + ASP +  KSPV++  + P + +  ++  E     AE+  P   + K  A+    SPP+
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEK--EEAKSPAEVKSP--EKAKSPAKEEAKSPPE 563

Query: 200 PKSSSSRMTSAPSQ 213
            KS       +P++
Sbjct: 564 AKSPEKEEAKSPAE 577



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 34/155 (21%), Positives = 64/155 (41%), Gaps = 13/155 (8%)

Query: 103 APAPRREKTNEELQEELRNLQEQMKALQEQLKV-----TTIKQTASPARLQKSPVEKSPR 157
           A A   EK    ++EE ++ ++    ++E+ K      + +K+ A      KSPV++  +
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745

Query: 158 PPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPD----PKSSSSRMTSAPSQ 213
            P K +  ++ +     S E   PA    K  AR+P    P+    P     +       
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPA----KEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801

Query: 214 PLQTISRNKPSGITRGQIVGTPGSSGETTQPICVE 248
           PL+  ++     I + + V +P    E  Q + V+
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 4/127 (3%)

Query: 89  EVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQ 148
           E   S + E    PA A   EK    ++EE ++  E    ++E+ K  +  +  SP +  
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK--SPAEVKSPEK-A 638

Query: 149 KSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTP-KASPPDPKSSSSRM 207
           KSP ++  + P K +  ++ +  +   A+  V A  ++   A++P KA    P+ + S +
Sbjct: 639 KSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698

Query: 208 TSAPSQP 214
                 P
Sbjct: 699 KEEAKSP 705



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 26/151 (17%), Positives = 65/151 (43%), Gaps = 12/151 (7%)

Query: 47  DADGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAP 106
           +A    + + E+A      E +  ++  + L  D +    E+E+P  +  ++ V      
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK--APEKEIPKKEEVKSPV------ 824

Query: 107 RREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQ 166
                 EE  +E++  +   KA +E+   T   +    ++ +++P +++P+P ++E++  
Sbjct: 825 ----KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880

Query: 167 RIQESTCFSAELDVPALPRTKRVARTPKASP 197
            +++      E         K+V    K +P
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 33/150 (22%), Positives = 64/150 (42%), Gaps = 23/150 (15%)

Query: 57  EEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQ 116
           EEA   E  ++ ++ + L       +  + E + PA +   +     P    EK    ++
Sbjct: 742 EEAKSPEKAKSPEKAKTL-------DVKSPEAKTPAKEEARSPADKFP----EKAKSPVK 790

Query: 117 EELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSA 176
           EE+++ ++    L+E  K    K+      + KSPV++  +P     +  +++E    + 
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPE-KEIPKKEEV-KSPVKEEEKP-----QEVKVKEPPKKAE 843

Query: 177 ELDVPALPRTK-----RVARTPKASPPDPK 201
           E   PA P+T+     +    PK   P PK
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPKPK 873



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 45/193 (23%), Positives = 75/193 (38%), Gaps = 13/193 (6%)

Query: 590 EVESPAVPSSSRQPPAQPPRTGSEFPRLEG--APATMTPKLGRGVLEGDDVLFYDESPPP 647
           EV+SP    S  +  A+ P    E P+ E   +P     K     ++       +E  P 
Sbjct: 792 EVKSPEKAKSPLKEDAKAPE--KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849

Query: 648 RPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQ 707
            PK     ++KK  A  K   K +V  K  P   K K+   +   E  E  +K      +
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 909

Query: 708 AEDEL---EPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKE 764
           A  ++   E A+ K + ++A  E ++      AK+K      E +    E+      K +
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDD------AKAKEPSKPAEKKEAAPEKKDTKEEKAK 963

Query: 765 QMEEKMRNIREVK 777
           + EEK +   + K
Sbjct: 964 KPEEKPKTEAKAK 976


>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
          Length = 250

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 10/147 (6%)

Query: 643 ESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEVKE 696
           E   PRPKL+A  + E +K+    I K R    +  L     +  + ++K+ ++++ +KE
Sbjct: 27  EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKE 86

Query: 697 RVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EMQE 754
           R+EK    + +AE +   A K+R  Q    E +  ++   AK +    LK+ +A   M  
Sbjct: 87  RIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 144

Query: 755 RYFEPLVKKEQMEEKMRNIREVKCRVV 781
            Y   L K +Q   K +  RE+K +++
Sbjct: 145 NYSSYLAKADQKRGKKQTAREMKKKIL 171


>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
          Length = 258

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 10/147 (6%)

Query: 643 ESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEVKE 696
           E   PRPKL+A  + E +K+    I K R    +  L     +  + ++K+ ++++ +KE
Sbjct: 35  EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKE 94

Query: 697 RVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EMQE 754
           R+EK    + +AE +   A K+R  Q    E +  ++   AK +    LK+ +A   M  
Sbjct: 95  RIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 152

Query: 755 RYFEPLVKKEQMEEKMRNIREVKCRVV 781
            Y   L K +Q   K +  RE+K +++
Sbjct: 153 NYSSYLAKADQKRGKKQTAREMKKKIL 179


>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
          Length = 250

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 10/147 (6%)

Query: 643 ESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEVKE 696
           E   PRPKL+A  + E +K+    I K R    +  L     +  + ++K+ ++++ +KE
Sbjct: 27  EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKE 86

Query: 697 RVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EMQE 754
           R+EK    + +AE +   A K+R  Q    E +  ++   AK +    LK+ +A   M  
Sbjct: 87  RIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 144

Query: 755 RYFEPLVKKEQMEEKMRNIREVKCRVV 781
            Y   L K +Q   K +  RE+K +++
Sbjct: 145 NYSSYLAKADQKRGKKQTAREMKKKIL 171


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 55/231 (23%), Positives = 94/231 (40%), Gaps = 29/231 (12%)

Query: 2   DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADD 61
           ++E  NL+   +  EE     D +SE     + E  EP A      +D + E   +   D
Sbjct: 71  NDEPLNLNASDSESEELHRQKDSDSE-----SEERAEPPA------SDSENEDVNQHGSD 119

Query: 62  GETGETR----DEKENLATLFGDMEDLTDEE--EVPASQSTENRVLPAPAPRREKTNEEL 115
            E+ ETR     + EN   L G   D  +E+  + PAS S    +  +PA   E T + L
Sbjct: 120 SESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSE-TEDAL 178

Query: 116 QEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQ---RIQEST 172
           + ++ +  E  +  + Q   +  ++   P R+  S  E+ P+P + +   +   R Q S 
Sbjct: 179 KPQISD-SESEEPPRHQASDSENEEPPKP-RMSDSESEELPKPQVSDSESEEPPRHQASD 236

Query: 173 CFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKP 223
             + EL  P      R++ +    PP  ++S S     P   +       P
Sbjct: 237 SENEELPKP------RISDSESEDPPRHQASDSENEELPKPRISDSESEDP 281


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 42/208 (20%), Positives = 88/208 (42%), Gaps = 23/208 (11%)

Query: 17  ENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDGETGETRDEKENLAT 76
           ++  A D +S+++      + + +A D   D+  D E+  + +DD E  + + +  ++  
Sbjct: 260 DDSEAPDDSSDDSEAPDDSSDDSEASD---DSSDDSEASDDSSDDSEAPDDKSDDSDVP- 315

Query: 77  LFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNE-ELQEELRNLQEQMKALQEQLKV 135
                ED +D+ +VP   S +   L  P P  +  NE ++  +   L E   A+ +    
Sbjct: 316 -----EDKSDDSDVPDDNSDD---LEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSS 367

Query: 136 TTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRT-KRVARTPK 194
               +      L K P +    P + ER++   +E          P + ++ KR ++T  
Sbjct: 368 DDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEE--------PAPVVEQSGKRKSKTKT 419

Query: 195 -ASPPDPKSSSSRMTSAPSQPLQTISRN 221
              PP  + + ++    P +  QT ++N
Sbjct: 420 IVEPPRKRQTKTKNIVEPPRKRQTKTKN 447


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 4/149 (2%)

Query: 83  DLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTA 142
           DL + E+   +   +N  L A   + E+   ELQ +LR++QE+ + +Q++L  +  +Q A
Sbjct: 646 DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEA 705

Query: 143 SPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPDPKS 202
           +  +L++   E   +  +  R VQ  +      A L+V    R + V R  +      + 
Sbjct: 706 ATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEV----RLQAVERDRQDLAEQLQG 761

Query: 203 SSSRMTSAPSQPLQTISRNKPSGITRGQI 231
            SS      S   +   +N    +T+GQ+
Sbjct: 762 LSSAKELLESSLFEAQQQNSVIEVTKGQL 790


>gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]
          Length = 970

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 51/167 (30%), Positives = 78/167 (46%), Gaps = 35/167 (20%)

Query: 86  DEEEVPASQSTENRVLPAPAPRRE-KTNEELQ----EELRNLQEQMKALQEQLKVTTIKQ 140
           D E+     S + + +P    R++ KT EE Q    E++R  QE+++ALQ   K T I+ 
Sbjct: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ---KTTPIR- 523

Query: 141 TASPARLQKSPVEKSPRPPLKE--RRVQRIQESTCFSAELDVPALP---RTKRVARTPKA 195
             S A L+K P+E + RP  +E  RR QR +     +   + P+ P    T R A  P+ 
Sbjct: 524 --SQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRK 581

Query: 196 SP---PDPK---------SSSSRMTSAPSQP-------LQTISRNKP 223
           +P     PK         +S+SR+   P  P       ++T SR  P
Sbjct: 582 APVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAP 628



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 46/227 (20%), Positives = 88/227 (38%), Gaps = 28/227 (12%)

Query: 566 KQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPA--- 622
           K+  LE+  R S E   R  Q      SP +P+  R  P++PP   +  P  +   A   
Sbjct: 529 KKLPLEVTTRPSTEEPVRRPQRP---RSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI 585

Query: 623 TMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIK 682
           + TPKL       +        PP  P+       K    + K  ++   L +    S+ 
Sbjct: 586 SSTPKLPALAAREEASTSRLLQPPEAPR-------KPANTLVKTASRPAPLVQQLSPSLL 638

Query: 683 KKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQK--------- 733
              K P+++   K  ++   +  +++  +L PA   R+  +A  + EE ++         
Sbjct: 639 PNSKSPREVPSPKV-IKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERC 697

Query: 734 -----ILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIRE 775
                ++K + K +  L ++  E      +   K + +  ++R  RE
Sbjct: 698 KRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNRE 744


>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
          Length = 256

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 10/149 (6%)

Query: 641 YDESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEV 694
           ++    PRPKL+A  + E +K+    I K R    +  L     +  + ++K+ ++++ +
Sbjct: 31  HEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVAL 90

Query: 695 KERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EM 752
           KER+EK    + +AE +   A K+R  Q    E +  ++   AK +    LK+ +A   M
Sbjct: 91  KERIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSM 148

Query: 753 QERYFEPLVKKEQMEEKMRNIREVKCRVV 781
              Y   L K +Q   K +  RE+K +++
Sbjct: 149 GANYSSYLAKADQKRGKKQTAREMKKKIL 177


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 5/103 (4%)

Query: 522 LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQ 581
           ++ LPT    N++  +A A A GIM  P   ++++ A++ L  Q Q++    +++ ++ Q
Sbjct: 138 VLTLPTANLTNIQGLVAAAAAGGIMTLP---LQNLQATSSLNSQLQQLQLQLQQQQQQQQ 194

Query: 582 KRFLQSSSEVESPA--VPSSSRQPPAQPPRTGSEFPRLEGAPA 622
           ++   S+++   PA   PS S+Q P QP       P  +  PA
Sbjct: 195 QQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPA 237


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 58/230 (25%), Positives = 94/230 (40%), Gaps = 37/230 (16%)

Query: 2   DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDA------------- 48
           DE+ +    LTA+ EE   A+    E+      +  EP+A +E   A             
Sbjct: 464 DEKSEMEEALTAITEE--LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVK 521

Query: 49  DGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVL---PAPA 105
           + +GE   EE  + E  E    K + A   G  ++ + E+E    +  E           
Sbjct: 522 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 581

Query: 106 PRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKS-----PRPPL 160
            + EK  EE  EE+   +E    L    KV   ++  SP  + KSPVE+      P+ P+
Sbjct: 582 AKEEKKVEEKSEEVATKEE----LVADAKVEKPEKAKSP--VPKSPVEEKGKSPVPKSPV 635

Query: 161 KERRVQRIQESTC-FSAELDVPALPRTKR----VARTP---KASPPDPKS 202
           +E+    + +S      +  VP  P  ++    V+++P   KA  P PKS
Sbjct: 636 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 685



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 24/214 (11%)

Query: 2   DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADD 61
           +EEED  +       +++ A +  SE+     +E GE +  +   +A+G+     EE   
Sbjct: 536 EEEEDEGA-------KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 588

Query: 62  GETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAP-APRREKTNEELQEELR 120
            E  E    KE L       +    +  VP S   E    P P +P  EK    + +   
Sbjct: 589 EEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS-- 646

Query: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCF------ 174
            ++E+ K+   +  V    +    + + KSPVE+  + P+ +  V+  +           
Sbjct: 647 PVEEKGKSPVPKSPV----EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQK 702

Query: 175 -SAELDVPALPRTKRVAR---TPKASPPDPKSSS 204
              E +V   P+ ++V +    PK  P   K+ S
Sbjct: 703 EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES 736



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 35/176 (19%), Positives = 74/176 (42%), Gaps = 12/176 (6%)

Query: 586 QSSSEVESPAVPSSSRQPPAQPP---RTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYD 642
           +  S V    V    + P ++ P   +  S  P+     A    ++G+G  + ++     
Sbjct: 651 KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 710

Query: 643 ESPPPRP------KLSALAEAKKLAAITKLRAKGQVLTKTNPNSI---KKKQKDPQDILE 693
           E+P          K   + E KK  +  K  A  +V+T T    +   K+ +++ + + +
Sbjct: 711 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 770

Query: 694 VKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAE 749
            KE+ +      S+ E   + A+  R+E +A     E ++ ++ ++K  G  +E E
Sbjct: 771 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 826


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 58/230 (25%), Positives = 94/230 (40%), Gaps = 37/230 (16%)

Query: 2   DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDA------------- 48
           DE+ +    LTA+ EE   A+    E+      +  EP+A +E   A             
Sbjct: 88  DEKSEMEEALTAITEE--LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVK 145

Query: 49  DGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVL---PAPA 105
           + +GE   EE  + E  E    K + A   G  ++ + E+E    +  E           
Sbjct: 146 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 205

Query: 106 PRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKS-----PRPPL 160
            + EK  EE  EE+   +E    L    KV   ++  SP  + KSPVE+      P+ P+
Sbjct: 206 AKEEKKVEEKSEEVATKEE----LVADAKVEKPEKAKSP--VPKSPVEEKGKSPVPKSPV 259

Query: 161 KERRVQRIQESTC-FSAELDVPALPRTKR----VARTP---KASPPDPKS 202
           +E+    + +S      +  VP  P  ++    V+++P   KA  P PKS
Sbjct: 260 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 309



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 24/214 (11%)

Query: 2   DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADD 61
           +EEED  +       +++ A +  SE+     +E GE +  +   +A+G+     EE   
Sbjct: 160 EEEEDEGA-------KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 212

Query: 62  GETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAP-APRREKTNEELQEELR 120
            E  E    KE L       +    +  VP S   E    P P +P  EK    + +   
Sbjct: 213 EEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS-- 270

Query: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCF------ 174
            ++E+ K+   +  V    +    + + KSPVE+  + P+ +  V+  +           
Sbjct: 271 PVEEKGKSPVPKSPV----EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQK 326

Query: 175 -SAELDVPALPRTKRVAR---TPKASPPDPKSSS 204
              E +V   P+ ++V +    PK  P   K+ S
Sbjct: 327 EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES 360



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 35/176 (19%), Positives = 74/176 (42%), Gaps = 12/176 (6%)

Query: 586 QSSSEVESPAVPSSSRQPPAQPP---RTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYD 642
           +  S V    V    + P ++ P   +  S  P+     A    ++G+G  + ++     
Sbjct: 275 KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 334

Query: 643 ESPPPRP------KLSALAEAKKLAAITKLRAKGQVLTKTNPNSI---KKKQKDPQDILE 693
           E+P          K   + E KK  +  K  A  +V+T T    +   K+ +++ + + +
Sbjct: 335 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 394

Query: 694 VKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAE 749
            KE+ +      S+ E   + A+  R+E +A     E ++ ++ ++K  G  +E E
Sbjct: 395 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 450


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)

Query: 406  LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 465
            LR     +  V+ + KKL A+  +LQS  S G       R    L +++ +       V 
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1290

Query: 466  SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 521
            S +   + A   A K  K   +LS+ +     L+ +ETRQKL +  K     EE    ++
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1350

Query: 522  LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 571
             +D      +NL++H++      +  S K      S    L++ K+R            E
Sbjct: 1351 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409

Query: 572  MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 630
             +    ++++K   +   E++   V   + RQ  +   +   +F +L      ++ K   
Sbjct: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1466

Query: 631  GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 688
                     + DE    R +  A A  K+  A++  RA  + L        + K  + + 
Sbjct: 1467 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513

Query: 689  QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 748
            +D++  K+ V KN     +++  LE   ++ + QL  LE +E Q    AK +    ++  
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1572

Query: 749  EAEMQERYFEPLVKKEQMEEKMRNIR 774
            + + +    +   + EQ EEK R ++
Sbjct: 1573 KGQFER---DLQARDEQNEEKRRQLQ 1595



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)

Query: 656  EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 710
            E +K   +TKL+ K + +       +KK++K  Q++ ++K ++E +   F  Q  D    
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077

Query: 711  --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 761
              EL+    K+ E+    LA L+ E  QK    K      ++E E   +++QE       
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1132

Query: 762  KKEQMEEKMRNIRE 775
             + + E++ R++ E
Sbjct: 1133 ARNKAEKQKRDLGE 1146


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)

Query: 406  LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 465
            LR     +  V+ + KKL A+  +LQS  S G       R    L +++ +       V 
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1297

Query: 466  SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 521
            S +   + A   A K  K   +LS+ +     L+ +ETRQKL +  K     EE    ++
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1357

Query: 522  LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 571
             +D      +NL++H++      +  S K      S    L++ K+R            E
Sbjct: 1358 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1416

Query: 572  MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 630
             +    ++++K   +   E++   V   + RQ  +   +   +F +L      ++ K   
Sbjct: 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1473

Query: 631  GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 688
                     + DE    R +  A A  K+  A++  RA  + L        + K  + + 
Sbjct: 1474 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520

Query: 689  QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 748
            +D++  K+ V KN     +++  LE   ++ + QL  LE +E Q    AK +    ++  
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1579

Query: 749  EAEMQERYFEPLVKKEQMEEKMRNIR 774
            + + +    +   + EQ EEK R ++
Sbjct: 1580 KGQFER---DLQARDEQNEEKRRQLQ 1602



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)

Query: 656  EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 710
            E +K   +TKL+ K + +       +KK++K  Q++ ++K ++E +   F  Q  D    
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084

Query: 711  --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 761
              EL+    K+ E+    LA L+ E  QK    K      ++E E   +++QE       
Sbjct: 1085 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1139

Query: 762  KKEQMEEKMRNIRE 775
             + + E++ R++ E
Sbjct: 1140 ARNKAEKQKRDLGE 1153


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)

Query: 406  LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 465
            LR     +  V+ + KKL A+  +LQS  S G       R    L +++ +       V 
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1297

Query: 466  SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 521
            S +   + A   A K  K   +LS+ +     L+ +ETRQKL +  K     EE    ++
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1357

Query: 522  LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 571
             +D      +NL++H++      +  S K      S    L++ K+R            E
Sbjct: 1358 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1416

Query: 572  MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 630
             +    ++++K   +   E++   V   + RQ  +   +   +F +L      ++ K   
Sbjct: 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1473

Query: 631  GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 688
                     + DE    R +  A A  K+  A++  RA  + L        + K  + + 
Sbjct: 1474 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520

Query: 689  QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 748
            +D++  K+ V KN     +++  LE   ++ + QL  LE +E Q    AK +    ++  
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1579

Query: 749  EAEMQERYFEPLVKKEQMEEKMRNIR 774
            + + +    +   + EQ EEK R ++
Sbjct: 1580 KGQFER---DLQARDEQNEEKRRQLQ 1602



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)

Query: 656  EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 710
            E +K   +TKL+ K + +       +KK++K  Q++ ++K ++E +   F  Q  D    
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084

Query: 711  --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 761
              EL+    K+ E+    LA L+ E  QK    K      ++E E   +++QE       
Sbjct: 1085 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1139

Query: 762  KKEQMEEKMRNIRE 775
             + + E++ R++ E
Sbjct: 1140 ARNKAEKQKRDLGE 1153


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)

Query: 406  LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 465
            LR     +  V+ + KKL A+  +LQS  S G       R    L +++ +       V 
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1290

Query: 466  SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 521
            S +   + A   A K  K   +LS+ +     L+ +ETRQKL +  K     EE    ++
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1350

Query: 522  LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 571
             +D      +NL++H++      +  S K      S    L++ K+R            E
Sbjct: 1351 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409

Query: 572  MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 630
             +    ++++K   +   E++   V   + RQ  +   +   +F +L      ++ K   
Sbjct: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1466

Query: 631  GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 688
                     + DE    R +  A A  K+  A++  RA  + L        + K  + + 
Sbjct: 1467 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513

Query: 689  QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 748
            +D++  K+ V KN     +++  LE   ++ + QL  LE +E Q    AK +    ++  
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1572

Query: 749  EAEMQERYFEPLVKKEQMEEKMRNIR 774
            + + +    +   + EQ EEK R ++
Sbjct: 1573 KGQFER---DLQARDEQNEEKRRQLQ 1595



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)

Query: 656  EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 710
            E +K   +TKL+ K + +       +KK++K  Q++ ++K ++E +   F  Q  D    
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077

Query: 711  --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 761
              EL+    K+ E+    LA L+ E  QK    K      ++E E   +++QE       
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1132

Query: 762  KKEQMEEKMRNIRE 775
             + + E++ R++ E
Sbjct: 1133 ARNKAEKQKRDLGE 1146


>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
          Length = 262

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 49/217 (22%), Positives = 92/217 (42%), Gaps = 33/217 (15%)

Query: 569 MLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKL 628
           M +   ++ EE Q     +  E E+P  P    +P  + P+     P     P  + PK+
Sbjct: 1   MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPK-----PSRPVVPPLIPPKI 55

Query: 629 GRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDP 688
                EG+ V F D       K   L E + L  +                  ++++K+ 
Sbjct: 56  P----EGERVDFDDIHRKRMEK--DLLELQTLIDV----------------HFEQRKKEE 93

Query: 689 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQK---ILKAKSKHTGIL 745
           ++++ +KER+E+     S+  ++     +K RE+ A L  E+ +K     K +++     
Sbjct: 94  EELVALKERIERR---RSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKK 150

Query: 746 KEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVT 782
           K+  + M   +   LVK EQ   K +  RE+K R+++
Sbjct: 151 KKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILS 187


>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
          Length = 278

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 49/217 (22%), Positives = 92/217 (42%), Gaps = 33/217 (15%)

Query: 569 MLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKL 628
           M +   ++ EE Q     +  E E+P  P    +P  + P+     P     P  + PK+
Sbjct: 1   MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPK-----PSRPVVPPLIPPKI 55

Query: 629 GRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDP 688
                EG+ V F D       K   L E + L  +                  ++++K+ 
Sbjct: 56  P----EGERVDFDDIHRKRMEK--DLLELQTLIDV----------------HFEQRKKEE 93

Query: 689 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQK---ILKAKSKHTGIL 745
           ++++ +KER+E+     S+  ++     +K RE+ A L  E+ +K     K +++     
Sbjct: 94  EELVALKERIERR---RSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKK 150

Query: 746 KEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVT 782
           K+  + M   +   LVK EQ   K +  RE+K R+++
Sbjct: 151 KKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILS 187


>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
           [Homo sapiens]
          Length = 1814

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 65/340 (19%), Positives = 142/340 (41%), Gaps = 49/340 (14%)

Query: 490 LVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSP 549
           LV+   + +I+E +  L   +  + C +E K  M  P        ++++     G+  +P
Sbjct: 214 LVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQMACPD-------ENVSSGELRGLCAAP 266

Query: 550 KPAIKSISASALLKQQKQR---------MLEMRRRKSEEI---QKRFLQSSSEVESPAVP 597
           +   +  + +A ++ QK+R         + E  R K  EI   +K  L+    ++   + 
Sbjct: 267 REEKERETEAAQMEHQKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMA 326

Query: 598 SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEA 657
             S++   +     SE  +L  A A     L +   +        E        +AL+  
Sbjct: 327 LKSKEKKVE--ELNSEIEKLSAAFAKAREALQKAQTQ--------EFQGSEDYETALSGK 376

Query: 658 KKLAAITKLRAKGQVLTKTNPN-----SIKKKQKDPQDILEVKERVEKNTMFSSQAEDEL 712
           + L+A  +     Q LTK+  N     SIKK  ++  D+ + +ER+EK+   + + + + 
Sbjct: 377 EALSAALR----SQNLTKSTENHRLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKG 432

Query: 713 EPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEM--QERYFEPLVKK------- 763
           +   +  R ++  L +E  ++    ++++  +L E+  ++  QE+  + L +        
Sbjct: 433 DCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIKHLTESTNQKDVL 492

Query: 764 -EQMEEKMRNIREVKCRVVTCKTCAYTHFKLL-ETCVSEQ 801
            ++  EK   + +  C ++  +        L+ E C S+Q
Sbjct: 493 LQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQ 532



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 15/152 (9%)

Query: 71   KENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQ 130
            +E+L+     +E L  E    AS   EN  L      +E+ N++L +E+R   +++  +Q
Sbjct: 1481 RESLSRKTVSLEHLQREY---ASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQ 1537

Query: 131  EQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAE-------LDVPAL 183
            E++K+     + +   LQ   VE      L E   +R+++   +  E        D    
Sbjct: 1538 EEVKLRQQLLSQNDKLLQSLRVELKAYEKLDEEH-RRLRDGDKYPMESDNSFDLFDSSQA 1596

Query: 184  PRTKRVARTPKASPPDPKS----SSSRMTSAP 211
               K V+ TP  S  D  S    S S  TS P
Sbjct: 1597 VTPKSVSETPPLSGNDTDSLSCDSGSSATSTP 1628


>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
           [Homo sapiens]
          Length = 1893

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 65/340 (19%), Positives = 142/340 (41%), Gaps = 49/340 (14%)

Query: 490 LVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSP 549
           LV+   + +I+E +  L   +  + C +E K  M  P        ++++     G+  +P
Sbjct: 214 LVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQMACPD-------ENVSSGELRGLCAAP 266

Query: 550 KPAIKSISASALLKQQKQR---------MLEMRRRKSEEI---QKRFLQSSSEVESPAVP 597
           +   +  + +A ++ QK+R         + E  R K  EI   +K  L+    ++   + 
Sbjct: 267 REEKERETEAAQMEHQKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMA 326

Query: 598 SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEA 657
             S++   +     SE  +L  A A     L +   +        E        +AL+  
Sbjct: 327 LKSKEKKVE--ELNSEIEKLSAAFAKAREALQKAQTQ--------EFQGSEDYETALSGK 376

Query: 658 KKLAAITKLRAKGQVLTKTNPN-----SIKKKQKDPQDILEVKERVEKNTMFSSQAEDEL 712
           + L+A  +     Q LTK+  N     SIKK  ++  D+ + +ER+EK+   + + + + 
Sbjct: 377 EALSAALR----SQNLTKSTENHRLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKG 432

Query: 713 EPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEM--QERYFEPLVKK------- 763
           +   +  R ++  L +E  ++    ++++  +L E+  ++  QE+  + L +        
Sbjct: 433 DCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIKHLTESTNQKDVL 492

Query: 764 -EQMEEKMRNIREVKCRVVTCKTCAYTHFKLL-ETCVSEQ 801
            ++  EK   + +  C ++  +        L+ E C S+Q
Sbjct: 493 LQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQ 532



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 4/102 (3%)

Query: 71   KENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQ 130
            +E+L+     +E L  E    AS   EN  L      +E+ N++L +E+R   +++  +Q
Sbjct: 1481 RESLSRKTVSLEHLQREY---ASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQ 1537

Query: 131  EQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQEST 172
            E++K+     + +   LQ   VE      L E   +R++E++
Sbjct: 1538 EEVKLRQQLLSQNDKLLQSLRVELKAYEKLDEEH-RRLREAS 1578


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 76/323 (23%), Positives = 122/323 (37%), Gaps = 36/323 (11%)

Query: 3    EEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDG 62
            EEE+ ++  +       SA     +EN+     + EP        A+ +GE+  E+ D G
Sbjct: 1049 EEEERMAPAS-----ESSASGAPLDENDLEEDVDSEP--------AEIEGEA-AEDGDPG 1094

Query: 63   ETGETRDEKENLATLFGDME-------DLTDEEEVPASQSTENRVLPAPAPRREKTNEEL 115
            +TG   D+ ++ +    D +           E E+    S +   LPA    +E+   + 
Sbjct: 1095 DTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQA 1154

Query: 116  QEELRNLQEQMKALQEQLKVTTIKQTASP---ARLQKSPVEKS-PRPPLKERRVQRIQES 171
               +R+ QE           +T      P   A  +KSP E+  P P L + + +    S
Sbjct: 1155 TSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPS 1214

Query: 172  TCFSAELDVPALPRTKRVARTPKA-SPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQ 230
               +    + + P T   ARTP +   P P+   +  T  PS PL   S+ +PS      
Sbjct: 1215 DLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPS-PLPICSQPQPS---TEA 1270

Query: 231  IVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLE 290
             V +P  S    QP    A +   L    V S    K   G  L     + E + R  L 
Sbjct: 1271 TVPSPTQSPIRFQP--APAKTSTPLAPLPVQSQSDTKDRLGSPL----AVDEALRRSDLV 1324

Query: 291  EIDWVTFGVILKKVTPQSVNSGK 313
            E  W+    I + +    V+  K
Sbjct: 1325 EEFWMKSAEIRRSLGLTPVDRSK 1347


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 57/245 (23%), Positives = 97/245 (39%), Gaps = 35/245 (14%)

Query: 544 GIMGSPKPAIK-----SISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPA--- 595
           G   SPK  ++       S SA   + K    + +RR S E  K     +S   SPA   
Sbjct: 499 GTTASPKGRVRRKEEAKESPSAAGPEDKS---QSKRRASNE--KESAAPASPAPSPAPSP 553

Query: 596 --VPSSSRQPPAQPPRTGSEF--PRLEGAPATMT-PKLGRGVLEGDDVLFYDESPPPRPK 650
              P    QPPA+ P   +    P     P T + P  G    E    L  ++    R +
Sbjct: 554 TPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQ 613

Query: 651 LSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAED 710
                + ++L A    R + + L +      +++        E + R E+     +QAE 
Sbjct: 614 REREEQERRLQAERDKRMREEQLAREAEARAEREA-------EARRREEQEAREKAQAEQ 666

Query: 711 ELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKM 770
           E +   +K++E+      EE ++    + KH    ++ E E QER       ++++EE M
Sbjct: 667 EEQERLQKQKEEAEARSREEAERQRLEREKH---FQQQEQERQER-------RKRLEEIM 716

Query: 771 RNIRE 775
           +  R+
Sbjct: 717 KRTRK 721



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 39/182 (21%), Positives = 72/182 (39%), Gaps = 21/182 (11%)

Query: 51  DGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREK 110
           + E+  E   +    E ++ +E       + E L  ++E   ++S E     A   R E+
Sbjct: 639 EAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREE----AERQRLER 694

Query: 111 TNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVE----KSPRPPLKERRVQ 166
             +  Q++ +  QE+ K L+E +K T   + +   + Q S        SP P        
Sbjct: 695 -EKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEP-------- 745

Query: 167 RIQESTCFSAELDVPALPRTKRVARTPKASPPD---PKSSSSRMTSAPSQPLQTISRNKP 223
            ++     S  L   A+ + + + + P+ S P    P S  + +   P+      S N P
Sbjct: 746 -VKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGP 804

Query: 224 SG 225
           SG
Sbjct: 805 SG 806


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 10/127 (7%)

Query: 654 LAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELE 713
           + E +K A   KL+   + L       I +KQ  P++I E +ER EK      + E E E
Sbjct: 473 MEEQRKAACAEKLKRLDEKL------GILEKQPSPEEIRE-RER-EKEREREKELEKEQE 524

Query: 714 PARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNI 773
             R+K RE+    + E+ +++ K + K   + KE + E +E+  E   +KE+  +KM+  
Sbjct: 525 QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE-KEKELERQKEKEKELQKMKE- 582

Query: 774 REVKCRV 780
           +E +C +
Sbjct: 583 QEKECEL 589



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 13/102 (12%)

Query: 682 KKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESE---EFQKILKAK 738
           K+++KD +   E ++ +EK      + + E+E  RK+ +E+    + E   E QK +K +
Sbjct: 529 KEREKDRERQQEKEKELEKE----QEKQREMEKERKQEKEKELERQKEKEKELQK-MKEQ 583

Query: 739 SKHTGILKEAE-----AEMQERYFEPLVKKEQMEEKMRNIRE 775
            K   + KE E      E +E   EP+V+K++ E       E
Sbjct: 584 EKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 38/178 (21%), Positives = 72/178 (40%), Gaps = 4/178 (2%)

Query: 57  EEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQ 116
           EE  + E  + R+ ++ L        +   E++    Q  E  +      +RE   E  Q
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561

Query: 117 EELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEK-SPRPPLKERRVQRIQ-ESTCF 174
           E+ + L+ Q +  +E  K+   ++     + ++   EK  PR P  E  V++ + E++C 
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCN 621

Query: 175 SAELDVPALPRTKRVAR--TPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQ 230
             E  V     + R  +  TP     +P+S S    +  S   +   ++ P    R Q
Sbjct: 622 KEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQ 679



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 78  FGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTT 137
           F   + + DE+E+   +  +   + A   R  K  EE   E R ++EQ KA   + K+  
Sbjct: 432 FPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREE---EERRMEEQRKAACAE-KLKR 487

Query: 138 IKQTASPARLQKSPVEKSPRPPLKERRVQR 167
           + +       Q SP E   R   KER  ++
Sbjct: 488 LDEKLGILEKQPSPEEIREREREKEREREK 517


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 61/253 (24%), Positives = 91/253 (35%), Gaps = 53/253 (20%)

Query: 50  GDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRRE 109
           G  +S +E + +  + E+  E+E       + ED  DEEE  +  S              
Sbjct: 472 GLAKSSSESSSEESSSESSSEEE-------EEEDEEDEEEEESESSD------------- 511

Query: 110 KTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRP-PLKERRVQRI 168
            + EE    L  LQEQ++A+ EQL           A L + P+ K  R    KE++ +R 
Sbjct: 512 -SEEERAHRLAELQEQLRAVHEQL-----------AALSQGPISKPKRKREKKEKKKKRK 559

Query: 169 QESTCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITR 228
            E     A  D        +  R P+  PP PK S     S         S   PSG   
Sbjct: 560 AEKHRGRAGAD-----EDDKGPRAPR--PPQPKKSKKASGSGGGSAALGPSGFGPSG--- 609

Query: 229 GQIVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNK-------KMTGRKL---IRLS 278
           G     P  + +T  P     +        R  S +  +       K+ G KL   + + 
Sbjct: 610 GSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHII 669

Query: 279 QIKEKMAREKLEE 291
           Q +E   R+   E
Sbjct: 670 QAREPSLRDSNPE 682


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 61/253 (24%), Positives = 91/253 (35%), Gaps = 53/253 (20%)

Query: 50  GDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRRE 109
           G  +S +E + +  + E+  E+E       + ED  DEEE  +  S              
Sbjct: 472 GLAKSSSESSSEESSSESSSEEE-------EEEDEEDEEEEESESSD------------- 511

Query: 110 KTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRP-PLKERRVQRI 168
            + EE    L  LQEQ++A+ EQL           A L + P+ K  R    KE++ +R 
Sbjct: 512 -SEEERAHRLAELQEQLRAVHEQL-----------AALSQGPISKPKRKREKKEKKKKRK 559

Query: 169 QESTCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITR 228
            E     A  D        +  R P+  PP PK S     S         S   PSG   
Sbjct: 560 AEKHRGRAGAD-----EDDKGPRAPR--PPQPKKSKKASGSGGGSAALGPSGFGPSG--- 609

Query: 229 GQIVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNK-------KMTGRKL---IRLS 278
           G     P  + +T  P     +        R  S +  +       K+ G KL   + + 
Sbjct: 610 GSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHII 669

Query: 279 QIKEKMAREKLEE 291
           Q +E   R+   E
Sbjct: 670 QAREPSLRDSNPE 682


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/194 (23%), Positives = 84/194 (43%), Gaps = 13/194 (6%)

Query: 594 PAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSA 653
           PA P+ +  P + P    +  P     PA M       V     V     +  P      
Sbjct: 424 PAAPAMAPAPASAPAPASAPAPAPVPTPA-MVSAPSSTVNASASVKTSAGTTDPEEATRL 482

Query: 654 LAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKD-PQDILEVK--ERVEKNTMFSSQAED 710
           LAE ++LA   + R K +   +      ++K+++  Q + E +   R E++    ++   
Sbjct: 483 LAEKRRLAR--EQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAR 540

Query: 711 ELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQER--YF-----EPLVKK 763
           E E   +++ E+ A  E EE ++  + K +   + +EAE   QER  +F     E L +K
Sbjct: 541 EKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERK 600

Query: 764 EQMEEKMRNIREVK 777
           +++EE M+  R  +
Sbjct: 601 KRLEEIMKRTRRTE 614


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 71/326 (21%), Positives = 135/326 (41%), Gaps = 30/326 (9%)

Query: 485 TTLSNLVVKGTNLIIQET-RQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATAS 543
           T  +++++     IIQE  R K  I +KS    E+  ++ +L     R ++Q  +     
Sbjct: 557 TMETSMIMSNIQRIIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQ--SNLMME 614

Query: 544 GIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSS-EVESPAVPSSSRQ 602
               S + A ++  A  L  +Q+      + + +EE+     Q S  +++  A      +
Sbjct: 615 KRNNSLQTATENTQARVLHAEQE------KAKVTEELAAATAQVSHLQLKMTAHQKKETE 668

Query: 603 PPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAA 662
              Q   +  E   L G    +  KL       +      +S     K   L        
Sbjct: 669 LQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEE 728

Query: 663 ITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR-- 720
           +T LR + + L K   N  ++K+K  Q+  + +E +++      +  D+L    KK R  
Sbjct: 729 LTDLRVEKESLEK---NLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVS 785

Query: 721 ------EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIR 774
                 EQL+ +++ E Q   +AK +H  +L  A+ E  ++Y E   +++  ++K+  ++
Sbjct: 786 TDQAAAEQLSLVQA-ELQTQWEAKCEH--LLASAKDEHLQQYQEVCAQRDAYQQKLVQLQ 842

Query: 775 EVKCRVVTCKTCAYT-----HFKLLE 795
           E KC  +  +  A T     H K LE
Sbjct: 843 E-KCLALQAQITALTKQNEQHIKELE 867



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 20/71 (28%), Positives = 43/71 (60%), Gaps = 6/71 (8%)

Query: 109 EKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRI 168
           ++T+E+ Q + ++ ++  K L+  LKVT++++  +  R++K  +EK+    L ER+ +  
Sbjct: 698 QETSEQAQSKFKSEKQNRKQLE--LKVTSLEEELTDLRVEKESLEKN----LSERKKKSA 751

Query: 169 QESTCFSAELD 179
           QE +    E+D
Sbjct: 752 QERSQAEEEID 762



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 54  SYTEEADDGETGETRDEKEN-------LATLFGDMEDLTDEEEVPASQSTENRVLPAPAP 106
           S  +E  +    + + EK+N       + +L  ++ DL  E+E      +E +     A 
Sbjct: 695 SELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERK--KKSAQ 752

Query: 107 RREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPA 145
            R +  EE+ E  ++ QE++  L++ LK T +    + A
Sbjct: 753 ERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAA 791


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,049,461
Number of Sequences: 37866
Number of extensions: 1855014
Number of successful extensions: 13259
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 667
Number of HSP's that attempted gapping in prelim test: 10948
Number of HSP's gapped (non-prelim): 3003
length of query: 875
length of database: 18,247,518
effective HSP length: 111
effective length of query: 764
effective length of database: 14,044,392
effective search space: 10729915488
effective search space used: 10729915488
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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