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Search of human proteins with 32996737
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32996737 lin-9 homolog [Homo sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32996737 lin-9 homolog [Homo sapiens] 1123 0.0
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom... 37 0.048
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ... 37 0.048
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 37 0.048
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 35 0.18
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 35 0.18
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap... 35 0.18
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 35 0.24
gi|19924145 T-cell, immune regulator 1 isoform a [Homo sapiens] 34 0.40
gi|16262452 cingulin [Homo sapiens] 34 0.40
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 34 0.40
gi|4557701 keratin 17 [Homo sapiens] 33 0.69
gi|145046269 rotatin [Homo sapiens] 33 0.90
gi|146260271 hypothetical protein LOC129881 [Homo sapiens] 32 1.5
gi|22748943 hypothetical protein LOC145483 [Homo sapiens] 32 1.5
gi|51317366 myosin XVIIIB [Homo sapiens] 32 2.0
gi|45439327 periplakin [Homo sapiens] 32 2.0
gi|4503593 epidermal growth factor receptor pathway substrate 15... 31 2.6
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 31 2.6
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 31 2.6
gi|238908508 leucine-rich repeat and death domain-containing pro... 31 3.4
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 31 3.4
gi|26667230 eyes absent 2 isoform c [Homo sapiens] 30 4.5
gi|94557295 mitogen-activated protein kinase 8 interacting prote... 30 4.5
gi|94557297 mitogen-activated protein kinase 8 interacting prote... 30 4.5
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 30 4.5
gi|154689847 hypothetical protein LOC9851 [Homo sapiens] 30 4.5
gi|156546890 WW and C2 domain containing 2 [Homo sapiens] 30 4.5
gi|229577185 epidermal growth factor receptor pathway substrate ... 30 5.8
gi|150010604 kinesin family member 4B [Homo sapiens] 30 7.6
>gi|32996737 lin-9 homolog [Homo sapiens]
Length = 558
Score = 1123 bits (2904), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MHRGGQPLKKRRGSFKMAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKG 60
MHRGGQPLKKRRGSFKMAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKG
Sbjct: 1 MHRGGQPLKKRRGSFKMAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKG 60
Query: 61 RNTSSAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQK 120
RNTSSAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQK
Sbjct: 61 RNTSSAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQK 120
Query: 121 IGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWG 180
IGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWG
Sbjct: 121 IGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWG 180
Query: 181 KIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGT 240
KIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGT
Sbjct: 181 KIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGT 240
Query: 241 KVTARLRGVHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPHETMPIAA 300
KVTARLRGVHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPHETMPIAA
Sbjct: 241 KVTARLRGVHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPHETMPIAA 300
Query: 301 FGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLI 360
FGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLI
Sbjct: 301 FGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLI 360
Query: 361 QVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNK 420
QVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNK
Sbjct: 361 QVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNK 420
Query: 421 VLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLI 480
VLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLI
Sbjct: 421 VLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLI 480
Query: 481 SRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVEIHVAHIQSG 540
SRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVEIHVAHIQSG
Sbjct: 481 SRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVEIHVAHIQSG 540
Query: 541 LSQMGNLHAFAANNTNRD 558
LSQMGNLHAFAANNTNRD
Sbjct: 541 LSQMGNLHAFAANNTNRD 558
>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 37.0 bits (84), Expect = 0.048
Identities = 45/205 (21%), Positives = 71/205 (34%), Gaps = 23/205 (11%)
Query: 279 THTIPDYEVLSNEPHETMPIAAFGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSP 338
+HT+P + V + H A P+ + P H TP +P P
Sbjct: 416 SHTLPSHPVTPSSKHADSKPAPL----TPAYHTLPHPSHHGTPHTTINWGPLEPPKTPKP 471
Query: 339 WRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISI 398
W L P R S L K++ K + M K K P
Sbjct: 472 W-------SLSCLRPAPP------LRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDE 518
Query: 399 EFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEI 458
EF R +T LE + ++L ++ YC Q L + + + E ++I
Sbjct: 519 EFASRKSTAALEEDA------QILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKI 572
Query: 459 VRHANSSTGQPCVENENLTDLISRL 483
+ S GQ +E ++L D + L
Sbjct: 573 IVEETKSNGQTVIEEKSLVDTVYAL 597
>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 37.0 bits (84), Expect = 0.048
Identities = 45/205 (21%), Positives = 71/205 (34%), Gaps = 23/205 (11%)
Query: 279 THTIPDYEVLSNEPHETMPIAAFGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSP 338
+HT+P + V + H A P+ + P H TP +P P
Sbjct: 416 SHTLPSHPVTPSSKHADSKPAPL----TPAYHTLPHPSHHGTPHTTINWGPLEPPKTPKP 471
Query: 339 WRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISI 398
W L P R S L K++ K + M K K P
Sbjct: 472 W-------SLSCLRPAPP------LRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDE 518
Query: 399 EFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEI 458
EF R +T LE + ++L ++ YC Q L + + + E ++I
Sbjct: 519 EFASRKSTAALEEDA------QILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKI 572
Query: 459 VRHANSSTGQPCVENENLTDLISRL 483
+ S GQ +E ++L D + L
Sbjct: 573 IVEETKSNGQTVIEEKSLVDTVYAL 597
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 37.0 bits (84), Expect = 0.048
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 385 EAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQP 444
E EK S+S + R ++ LELE+LN L + K ++ E+A D+ + Q
Sbjct: 56 EIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKE--LEIAQDRNIAIQSQF 113
Query: 445 TDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRL 483
T + E E ++++R N Q E E LT+ + RL
Sbjct: 114 TRTKEELEAEKRDLIR-TNERLSQ---ELEYLTEDVKRL 148
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 356 VEFLIQVTRLSKILMIKKEHIKKLREMN-------TEAEKLKSYSMPISIEFQRRY---A 405
V+ L+QV+R + +M K+E + K+RE TE E L+S M ++ Q +
Sbjct: 834 VKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAET 893
Query: 406 TIVLELEQLNKDLNKVLHKVQQYCYEL 432
+ E E+L L ++++ C++L
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDL 920
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
Length = 2365
Score = 35.0 bits (79), Expect = 0.18
Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 410 ELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQP 469
++E L ++L + + Q C E+ ++ A++ RRC++E QE++RH G+
Sbjct: 2194 DVEALKRELQVLSEQYSQKCLEIGAL--MRQAEEREHTLRRCQQEGQELLRHNQELHGRL 2251
Query: 470 CVENENLTDLIS 481
E + L I+
Sbjct: 2252 SEEIDQLRGFIA 2263
>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo
sapiens]
Length = 652
Score = 35.0 bits (79), Expect = 0.18
Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 410 ELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQP 469
++E L ++L + + Q C E+ ++ A++ RRC++E QE++RH G+
Sbjct: 481 DVEALKRELQVLSEQYSQKCLEIGAL--MRQAEEREHTLRRCQQEGQELLRHNQELHGRL 538
Query: 470 CVENENLTDLIS 481
E + L I+
Sbjct: 539 SEEIDQLRGFIA 550
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 34.7 bits (78), Expect = 0.24
Identities = 59/316 (18%), Positives = 118/316 (37%), Gaps = 40/316 (12%)
Query: 191 RCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGTKVTARLRGVH 250
+C+ AF +E+ + + ++I+ LQ+ V + K L + V+ K ++
Sbjct: 797 KCNLAFQRDEK--VLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEK 854
Query: 251 DGLFTGQIDAVDTLNATYRVTFDRTGL------GTHTIPDYEVLSNEP------HETMPI 298
+ L Q D ++ NA + + L + T E+ + + HE +
Sbjct: 855 EAL---QSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP 911
Query: 299 AAFGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEF 358
++ R R + L +SP + NDPL KI
Sbjct: 912 LLEQKELRDRRAELI---LLKDSLAKSPSVKNDPLSSVKELEEKIE-------------- 954
Query: 359 LIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDL 418
L K K+E I K++ + +A+K S + + ++ E +QL+ +
Sbjct: 955 -----NLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASM 1009
Query: 419 NKVLHKVQQYCYELAP-DQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLT 477
++ + Y L ++ + D + E +++ R +ST Q N +
Sbjct: 1010 RDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNE 1069
Query: 478 DLISRLTAILLQIKCL 493
DL++R+ + K L
Sbjct: 1070 DLLARIETLQSNAKLL 1085
Score = 30.0 bits (66), Expect = 5.8
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 334 LGQSPWRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYS 393
L S + + SD E L +E L +L ++ +++ + K + + EAEKL+
Sbjct: 1054 LRNSTLQCETINSDNEDLLA-RIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQ 1112
Query: 394 MPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYEL 432
+ +AT V ELE+L L K ++Q+ EL
Sbjct: 1113 KI------KEHATTVNELEELQVQLQKEKKQLQKTMQEL 1145
>gi|19924145 T-cell, immune regulator 1 isoform a [Homo sapiens]
Length = 830
Score = 33.9 bits (76), Expect = 0.40
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 400 FQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIV 459
FQRR+ V E+L K + +V++ L P +G PA P D+ R +EE + +
Sbjct: 47 FQRRFVVDVRRCEELEKTFTFLQEEVRRAGLVLPPPKGRLPAPPPRDL-LRIQEETERLA 105
Query: 460 RHANSSTG 467
+ G
Sbjct: 106 QELRDVRG 113
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 33.9 bits (76), Expect = 0.40
Identities = 41/197 (20%), Positives = 80/197 (40%), Gaps = 21/197 (10%)
Query: 361 QVTRLSKILMIKKEHIKKL---REMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKD 417
QV L K L+ +E +K+L R+ A + + + + R A ELE+ N
Sbjct: 626 QVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQ 685
Query: 418 LNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLT 477
L K L +++Q C E + + + A+ +RR E ++ + EN+
Sbjct: 686 LQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVE---------TTLRETQEENDEFR 736
Query: 478 DLISRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDAS---------NISCFQN 528
I L L + + L +GG+ + L K ++ + +++ +
Sbjct: 737 RRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKR 796
Query: 529 NVEIHVAHIQSGLSQMG 545
+E + Q GL+++G
Sbjct: 797 ALEARLEEAQRGLARLG 813
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 33.9 bits (76), Expect = 0.40
Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 9/128 (7%)
Query: 364 RLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLH 423
R+S IL KE K + M K K+ P E+ R +T LE + ++L
Sbjct: 611 RMSYIL---KESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDA------QILK 661
Query: 424 KVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRL 483
++ YC QG + + + + E ++++ S GQ +E ++L D + L
Sbjct: 662 VIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYAL 721
Query: 484 TAILLQIK 491
+ ++K
Sbjct: 722 KDEVRELK 729
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 33.1 bits (74), Expect = 0.69
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 18/144 (12%)
Query: 380 REMNTEAEKLKSYSMPISIEFQRRYATIVLELEQ---LNKDLNKVLHKVQ-QYCYELAPD 435
RE+ T +E ++S IS E +R + +EL+ + L L + + +YC +L+
Sbjct: 284 REVATNSELVQSGKSEIS-ELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQI 342
Query: 436 QGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRLTAILLQIKCLAE 495
QGL + + + RCE E Q E + L D+ +RL + + L E
Sbjct: 343 QGLIGSVEEQLAQLRCEMEQQN-------------QEYKILLDVKTRLEQEIATYRRLLE 389
Query: 496 GGDLNSFEFKSLTDSLNDIKSTID 519
G D + ++K + +++ ++
Sbjct: 390 GEDAHLTQYKKEPVTTRQVRTIVE 413
>gi|145046269 rotatin [Homo sapiens]
Length = 2226
Score = 32.7 bits (73), Expect = 0.90
Identities = 20/69 (28%), Positives = 35/69 (50%)
Query: 364 RLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLH 423
RL + L+ ++ + L E + A L S MPIS+E+ + +V LEQLN + +
Sbjct: 482 RLLQTLLPVEKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIYK 541
Query: 424 KVQQYCYEL 432
+ + Y +
Sbjct: 542 RTAEAVYSI 550
>gi|146260271 hypothetical protein LOC129881 [Homo sapiens]
Length = 552
Score = 32.0 bits (71), Expect = 1.5
Identities = 20/90 (22%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 371 IKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCY 430
+ K+H+K+++E E E+ K Y + E +R+ A +E+ + + + +H+ ++
Sbjct: 214 LAKDHLKQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKKREEMHESRRRFL 273
Query: 431 ELAPDQGLQPADQPTDMRRRCEEEAQEIVR 460
E D+ + A + ++ +EE E +R
Sbjct: 274 EHMQDKHIIKA-----VEQQQQEEEDEKMR 298
>gi|22748943 hypothetical protein LOC145483 [Homo sapiens]
Length = 647
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 9/80 (11%)
Query: 118 SQKIGFRLRNLLKLPKAHKWCIYEWFYSN---IDKPLFEGDNDFCVCLKESFPNLKTRKL 174
S G +NL +L + +WC+ E + + D+ L E + D ESF K R +
Sbjct: 61 SDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDL-----ESFFQDKDRGM 115
Query: 175 TRVEWGKIRRLMGKPRRCSS 194
+V+ + R G RRCSS
Sbjct: 116 VQVQCPQALR-CGSTRRCSS 134
>gi|51317366 myosin XVIIIB [Homo sapiens]
Length = 2567
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/111 (22%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 360 IQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQL---NK 416
+Q+ R +++ ++ + K+ E ++A +S S +QRR + ++E+L
Sbjct: 1984 VQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREA 2043
Query: 417 DLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCE-EEAQEIVRHANSST 466
+ ++ ++++Y ELA + D T +RR + + A E V ++S T
Sbjct: 2044 EASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDT 2094
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 31.6 bits (70), Expect = 2.0
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 21/118 (17%)
Query: 357 EFLIQVTRLSKILMI---KKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQ 413
++ ++ +L +L + + H+ K + + A K+K ++ +F YA L+
Sbjct: 800 DYELEAEKLRSLLDLENGRSSHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQN 859
Query: 414 LNKDLN--------KVLHKVQQYCYELAPDQGLQPA-------DQPTDMRRRCEEEAQ 456
L LN +V H+ Q PD G++ A D+ T+ RR+ E E +
Sbjct: 860 LEFALNLLRQQPEVEVTHETLQ---RNRPDSGVEEAWKIRKELDEETERRRQLENEVK 914
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 22/195 (11%)
Query: 376 IKKLREMNTEAEKLKSYSMPISIEFQRRYATIVL----------ELEQLNKDLNKVL--- 422
IK+L +N E L+ + + + + TI E+++ N +L K+
Sbjct: 332 IKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK 391
Query: 423 HKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQ---EIVRHANSSTGQPCVENENLTDL 479
+VQ+ EL +Q Q +Q ++R++C EEAQ + S Q E L
Sbjct: 392 QQVQELLDEL-DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKA 450
Query: 480 ISRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQ-NNVEIHVAHIQ 538
L+ + + L E + + + L L D + I + + + ++E H
Sbjct: 451 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENH----N 506
Query: 539 SGLSQMGNLHAFAAN 553
S L+ + H+ N
Sbjct: 507 SQLNWCSSPHSILVN 521
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 31.2 bits (69), Expect = 2.6
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 442 DQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRLTAI------LLQIKCLAE 495
++ D++++ + AQE R S+T E+ NLT+ IS+ I LL +K ++E
Sbjct: 547 EERLDLKKKIRQMAQE--RGKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKNMSE 604
Query: 496 GGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVE 531
N F + L + D++ + + I+ FQN ++
Sbjct: 605 AQSKNEFLSRELIEKERDLERS--RTVIAKFQNKLK 638
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 31.2 bits (69), Expect = 2.6
Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 10/114 (8%)
Query: 5 GQPLKKRRGSFKMAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKG-RNT 63
G P KK K L P ++AKA S S+ +E+ +K PV KG +
Sbjct: 99 GPPAKKAAVPAKRVGL---PPGKAAAKASESSSSEESSDDDDEE--DQKKQPVQKGVKPQ 153
Query: 64 SSAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKA 117
+ A + P + +K S D D + P +NQ+ + P A P K A
Sbjct: 154 AKAAKAPPKKAKSS----DSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPA 203
>gi|238908508 leucine-rich repeat and death domain-containing
protein [Homo sapiens]
Length = 860
Score = 30.8 bits (68), Expect = 3.4
Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 494 AEGGDLNSFEFKSLTDS-LNDIKSTIDASNISCFQNNVEIHVAHIQSGLSQMGNL-HAFA 551
A+ GDL E SL ++ L+ + S I + N H++HI +SQ+GN+ F
Sbjct: 182 ADSGDLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFF 241
Query: 552 ANN 554
NN
Sbjct: 242 YNN 244
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 30.8 bits (68), Expect = 3.4
Identities = 18/100 (18%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 360 IQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDL- 418
+Q ++ + +E +KL+ + +++++ + + + ++F+ + + E E++N L
Sbjct: 263 LQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLA 322
Query: 419 NKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEI 458
N+ H Q + Q ++ ++ ++ EEE QE+
Sbjct: 323 NQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQEL 362
>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
Length = 514
Score = 30.4 bits (67), Expect = 4.5
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 287 VLSNEPHETMPIAAFGQKQRPSRFFMTPPRLHYTPPLQS---PIIDNDPLLGQSPWRSKI 343
VL +P M AA+GQ Q + P Y PP Q+ P P GQSP+ ++
Sbjct: 57 VLPRQPSTAM--AAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSP-TGQSPYTYQM 113
Query: 344 SGSDTETLGG 353
G+ GG
Sbjct: 114 HGTTGFYQGG 123
>gi|94557295 mitogen-activated protein kinase 8 interacting protein
3 isoform 2 [Homo sapiens]
Length = 1330
Score = 30.4 bits (67), Expect = 4.5
Identities = 19/81 (23%), Positives = 33/81 (40%)
Query: 21 DQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNTSSAVEMPFRNSKRSRLF 80
D++ + S+ A G+ SNT S TP+ + + +NSKR+R
Sbjct: 252 DEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREK 311
Query: 81 SDEDDRQINTRSPKRNQRVAM 101
D + ++ RN + M
Sbjct: 312 RDSRNMEVQVTQEMRNVSIGM 332
>gi|94557297 mitogen-activated protein kinase 8 interacting protein
3 isoform 1 [Homo sapiens]
Length = 1336
Score = 30.4 bits (67), Expect = 4.5
Identities = 19/81 (23%), Positives = 33/81 (40%)
Query: 21 DQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNTSSAVEMPFRNSKRSRLF 80
D++ + S+ A G+ SNT S TP+ + + +NSKR+R
Sbjct: 252 DEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRAREK 311
Query: 81 SDEDDRQINTRSPKRNQRVAM 101
D + ++ RN + M
Sbjct: 312 RDSRNMEVQVTQEMRNVSIGM 332
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 30.4 bits (67), Expect = 4.5
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 6/62 (9%)
Query: 368 ILMIKK--EHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKV 425
+L+ KK EH++KL E N E +K ++ I + + R+ L++E+L + L K ++
Sbjct: 542 VLLKKKLEEHLEKLHEANNELQKKRA----IIEDLEPRFNNSSLKIEELQEALRKKEEEM 597
Query: 426 QQ 427
+Q
Sbjct: 598 KQ 599
>gi|154689847 hypothetical protein LOC9851 [Homo sapiens]
Length = 967
Score = 30.4 bits (67), Expect = 4.5
Identities = 15/53 (28%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Query: 408 VLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVR 460
+LE+++L K+L+ +HK+++ + ++ L P D+ +R R +E+A R
Sbjct: 216 LLEVQRLQKELSSCIHKIEEVTKKDRLEEALDP-DEERRIRIRRQEQAARSAR 267
>gi|156546890 WW and C2 domain containing 2 [Homo sapiens]
Length = 1192
Score = 30.4 bits (67), Expect = 4.5
Identities = 26/126 (20%), Positives = 48/126 (38%), Gaps = 17/126 (13%)
Query: 344 SGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRR 403
+GS T G V + ++ + +E + + + E KL S + P +++ ++
Sbjct: 284 AGSQTSISGDIGVRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDSEAWPGALDIEKE 343
Query: 404 YATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHAN 463
++ E E+L K+L Q + P + D R E E Q +
Sbjct: 344 KLMLINEKEELLKEL-----------------QFVTPQKRTQDELERLEAERQRLEEELL 386
Query: 464 SSTGQP 469
S G P
Sbjct: 387 SVRGTP 392
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 30.0 bits (66), Expect = 5.8
Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 12/151 (7%)
Query: 410 ELEQLNKDLNKVL---HKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQ---EIVRHAN 463
E+++ N +L K+ +VQ+ EL +Q Q +Q ++R++C EEAQ +
Sbjct: 62 EVQRENTNLQKLQAQKQQVQELLDEL-DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELT 120
Query: 464 SSTGQPCVENENLTDLISRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNI 523
S Q E L L+ + + L E + + + L L D + I + +
Sbjct: 121 SQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 180
Query: 524 SCFQ-NNVEIHVAHIQSGLSQMGNLHAFAAN 553
+ ++E H S L+ + H+ N
Sbjct: 181 KLMEMKDLENH----NSQLNWCSSPHSILVN 207
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 29.6 bits (65), Expect = 7.6
Identities = 41/200 (20%), Positives = 84/200 (42%), Gaps = 20/200 (10%)
Query: 367 KILMIKKEHIKKLREMNTEAEKLKSYSMPIS---IEFQRRYATIVLELEQLNKDLNKVLH 423
+I M+K + ++ +R+M +AEK + + I+ + R EL +L ++ K
Sbjct: 639 EIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSS 698
Query: 424 KVQQYCYELAP-----DQGLQPADQPTDMRRRCEEEAQE----IVRHANSSTGQPCVENE 474
+++ E A LQ + TD R+ + +E VR+ + + V E
Sbjct: 699 VLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTE 758
Query: 475 ----NLTDLISR---LTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQ 527
+L DL+ L ++Q+K E + + + T SL+++ + S C
Sbjct: 759 EAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESE-DCIT 817
Query: 528 NNVEIHVAHIQSGLSQMGNL 547
+E ++ +Q+ +L
Sbjct: 818 KQIESLETEMELRSAQIADL 837
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,721,104
Number of Sequences: 37866
Number of extensions: 948063
Number of successful extensions: 3011
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 2983
Number of HSP's gapped (non-prelim): 61
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.